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Conserved domains on  [gi|159163021|pdb|1SRZ|A]
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Chain A, Gamma-aminobutyric acid type B receptor, subunit 1

Protein Classification

CCP domain-containing protein( domain architecture ID 10442273)

CCP domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Sushi pfam00084
Sushi repeat (SCR repeat);
15-65 1.70e-10

Sushi repeat (SCR repeat);


:

Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 50.58  E-value: 1.70e-10
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|..
1SRZ_A        15 LENGKVflTGGDLPALDGARVEFRCDPDFHLVGSSRSVCSQ-GQWSTPKPHC 65
Cdd:pfam00084  7 IPNGKV--SATKNEYNYGASVSYECDPGYRLVGSPTITCQEdGTWSPPFPEC 56
 
Name Accession Description Interval E-value
Sushi pfam00084
Sushi repeat (SCR repeat);
15-65 1.70e-10

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 50.58  E-value: 1.70e-10
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|..
1SRZ_A        15 LENGKVflTGGDLPALDGARVEFRCDPDFHLVGSSRSVCSQ-GQWSTPKPHC 65
Cdd:pfam00084  7 IPNGKV--SATKNEYNYGASVSYECDPGYRLVGSPTITCQEdGTWSPPFPEC 56
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 14-66 3.10e-09

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 47.46  E-value: 3.10e-09
                       10        20        30        40        50
               ....*....|....*....|....*....|....*....|....*....|....
1SRZ_A      14 TLENGKVFLTGGDLPAldGARVEFRCDPDFHLVGSSRSVC-SQGQWSTPKPHCQ 66
Cdd:cd00033  6 VPENGTVTGSKGSYSY--GSTVTYSCNEGYTLVGSSTITCtENGGWSPPPPTCE 57
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 14-65 9.15e-09

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 46.37  E-value: 9.15e-09
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
1SRZ_A         14 TLENGKVFLTGGDLPAldGARVEFRCDPDFHLVGSSRSVC-SQGQWSTPKPHC 65
Cdd:smart00032  6 DIENGTVTSSSGTYSY--GDTVTYSCDPGYTLIGSSTITClENGTWSPPPPTC 56
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 31-67 8.59e-06

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 41.18  E-value: 8.59e-06
                         10        20        30
                 ....*....|....*....|....*....|....*..
1SRZ_A        31 DGARVEFRCDPDFHLVGSSRSVCSQGQWSTPkPHCQV 67
Cdd:PHA02927 168 DGSVVTYSCNSGYSLIGNSGVLCSGGEWSDP-PTCQI 203
 
Name Accession Description Interval E-value
Sushi pfam00084
Sushi repeat (SCR repeat);
15-65 1.70e-10

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 50.58  E-value: 1.70e-10
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|..
1SRZ_A        15 LENGKVflTGGDLPALDGARVEFRCDPDFHLVGSSRSVCSQ-GQWSTPKPHC 65
Cdd:pfam00084  7 IPNGKV--SATKNEYNYGASVSYECDPGYRLVGSPTITCQEdGTWSPPFPEC 56
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 14-66 3.10e-09

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 47.46  E-value: 3.10e-09
                       10        20        30        40        50
               ....*....|....*....|....*....|....*....|....*....|....
1SRZ_A      14 TLENGKVFLTGGDLPAldGARVEFRCDPDFHLVGSSRSVC-SQGQWSTPKPHCQ 66
Cdd:cd00033  6 VPENGTVTGSKGSYSY--GSTVTYSCNEGYTLVGSSTITCtENGGWSPPPPTCE 57
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 14-65 9.15e-09

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 46.37  E-value: 9.15e-09
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
1SRZ_A         14 TLENGKVFLTGGDLPAldGARVEFRCDPDFHLVGSSRSVC-SQGQWSTPKPHC 65
Cdd:smart00032  6 DIENGTVTSSSGTYSY--GDTVTYSCDPGYTLIGSSTITClENGTWSPPPPTC 56
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 31-67 8.59e-06

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 41.18  E-value: 8.59e-06
                         10        20        30
                 ....*....|....*....|....*....|....*..
1SRZ_A        31 DGARVEFRCDPDFHLVGSSRSVCSQGQWSTPkPHCQV 67
Cdd:PHA02927 168 DGSVVTYSCNSGYSLIGNSGVLCSGGEWSDP-PTCQI 203
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 15-66 6.65e-03

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 32.70  E-value: 6.65e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
1SRZ_A        15 LENGKVFLTGGDLpaldGARVEFRCDPDFHLVGSSRSVCSQGQ-----WSTPKPHCQ 66
Cdd:PHA02927  92 IDNGQLDIGGVDF----GSSITYSCNSGYQLIGESKSYCELGStgsmvWNPEAPICE 144
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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