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Conserved domains on  [gi|573483785|gb|AHG02193|]
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cation:proton antiporter (plasmid) [Halostagnicola larsenii XH-48]

Protein Classification

monovalent cation/H+ antiporter subunit E( domain architecture ID 10014033)

monovalent cation/H+ antiporter subunit E similar to Na+/H+ antiporter subunit E, which is part of a Na+/H+ prokaryotic antiporter complex that consists of seven subunits (MrpABCDEFG) and is involved in Na+ execretion

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PRK12652 PRK12652
monovalent cation/H+ antiporter subunit E;
1-341 0e+00

monovalent cation/H+ antiporter subunit E;


:

Pssm-ID: 237160 [Multi-domain]  Cd Length: 357  Bit Score: 506.21  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 573483785   1 MATNQILVPLSDTVTVRQTVGYAVQSALEDSDELVCHLVVALPQDGTDPTGESSIEEAEQLLERATSWVHEDAG--SATV 78
Cdd:PRK12652   3 MAANRLLVPVADSVTVRQTVAYAVESAEEAAETPTVHLVAAASGRAVDPEGQDELAAAEELLERVEVWATEDLGddASSV 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 573483785  79 SVETSILGSTEYLFGPRQFAEAFVAYADEHGLDCIVLDPEYRPGVTAPMLQPLERELSNVGLEYDEAPVDRPAQHARLVV 158
Cdd:PRK12652  83 TIETALLGTDEYLFGPGDYAEVLIAYAEEHGIDRVVLDPEYNPGGTAPMLQPLERELARAGITYEEAPVERPTRRGRLVR 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 573483785 159 QESFDRMFALFWISYAFYLVLGDPTYWFDLVTGAAVAGIVAVSLSSITFTVAPDRIQSPLRTVRFVLYVPYLAYEIVKAN 238
Cdd:PRK12652 163 AATLDKFAALFGASFGFYLLLGDPLYWFDLLTGAVTALIVAVLLAHVTFSRPPSLRRTPLRVLRFLLYVPYLLWEIVKAN 242

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 573483785 239 LAISVVILRPSMPIEPTVTRLEARVGGGLPLLALANSITLTPGTLTVRANDQRLIVHTLIPSAREDLFGGSLERAVRFVF 318
Cdd:PRK12652 243 VAIAYVILHPSLPIDPTMVRVRAAVRSGLPLTTLANSITLTPGTLTVDVDDRHLLVHSLTPSAREDLFDGGLERAVRFVF 322

                        330       340
                 ....*....|....*....|...
gi 573483785 319 YGRDSASIPTPEERGDAEIVGGD 341
Cdd:PRK12652 323 YGRAAARIPSPAERGDTPDLSVP 345
 
Name Accession Description Interval E-value
PRK12652 PRK12652
monovalent cation/H+ antiporter subunit E;
1-341 0e+00

monovalent cation/H+ antiporter subunit E;


Pssm-ID: 237160 [Multi-domain]  Cd Length: 357  Bit Score: 506.21  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 573483785   1 MATNQILVPLSDTVTVRQTVGYAVQSALEDSDELVCHLVVALPQDGTDPTGESSIEEAEQLLERATSWVHEDAG--SATV 78
Cdd:PRK12652   3 MAANRLLVPVADSVTVRQTVAYAVESAEEAAETPTVHLVAAASGRAVDPEGQDELAAAEELLERVEVWATEDLGddASSV 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 573483785  79 SVETSILGSTEYLFGPRQFAEAFVAYADEHGLDCIVLDPEYRPGVTAPMLQPLERELSNVGLEYDEAPVDRPAQHARLVV 158
Cdd:PRK12652  83 TIETALLGTDEYLFGPGDYAEVLIAYAEEHGIDRVVLDPEYNPGGTAPMLQPLERELARAGITYEEAPVERPTRRGRLVR 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 573483785 159 QESFDRMFALFWISYAFYLVLGDPTYWFDLVTGAAVAGIVAVSLSSITFTVAPDRIQSPLRTVRFVLYVPYLAYEIVKAN 238
Cdd:PRK12652 163 AATLDKFAALFGASFGFYLLLGDPLYWFDLLTGAVTALIVAVLLAHVTFSRPPSLRRTPLRVLRFLLYVPYLLWEIVKAN 242

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 573483785 239 LAISVVILRPSMPIEPTVTRLEARVGGGLPLLALANSITLTPGTLTVRANDQRLIVHTLIPSAREDLFGGSLERAVRFVF 318
Cdd:PRK12652 243 VAIAYVILHPSLPIDPTMVRVRAAVRSGLPLTTLANSITLTPGTLTVDVDDRHLLVHSLTPSAREDLFDGGLERAVRFVF 322

                        330       340
                 ....*....|....*....|...
gi 573483785 319 YGRDSASIPTPEERGDAEIVGGD 341
Cdd:PRK12652 323 YGRAAARIPSPAERGDTPDLSVP 345
MnhE COG1863
Multisubunit Na+/H+ antiporter, MnhE subunit [Inorganic ion transport and metabolism];
162-319 5.79e-35

Multisubunit Na+/H+ antiporter, MnhE subunit [Inorganic ion transport and metabolism];


Pssm-ID: 441468  Cd Length: 162  Bit Score: 125.28  E-value: 5.79e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 573483785 162 FDRMFALFWISYAFYLVLGDPTYWFDLVTGAAVAGIVAVslssITFTVAPDRIQSPLRTVRFVLYVPYLAYEIVKANLAI 241
Cdd:COG1863    4 LLPHLLLSLLLALVWLLLSGSFSPGNLLLGLLLALLVLL----LFRRLPPPRLPYLRRPLRLLRLLLYFLWDIVVANIDV 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 573483785 242 SVVILRPSMPIEPTVTRLEARVGGGLPLLALANSITLTPGTLTVRANDQR--LIVHTLIPSAREDL---FGGSLERAVRF 316
Cdd:COG1863   80 ARRVLRPRLPIRPGIVAVPLRLRSDLGITLLANSITLTPGTLTVDVDDDRrtLYVHALDVDDPEALieeIKGRYERRLLE 159


                 ...
gi 573483785 317 VFY 319
Cdd:COG1863  160 IFE 162
MNHE pfam01899
Na+/H+ ion antiporter subunit; Subunit of a Na+/H+ Prokaryotic antiporter complex.
 169-317 1.11e-29

Na+/H+ ion antiporter subunit; Subunit of a Na+/H+ Prokaryotic antiporter complex.


Pssm-ID: 460378  Cd Length: 150  Bit Score: 111.01  E-value: 1.11e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 573483785  169 FWISYAFYLVLGDPTYWFDLVTGAAVAGIVAVSLSSITftvaPDRIQSPLRTVRFVLYVPYLAYEIVKANLAISVVILRP 248
Cdd:pfam01899   1 NLLLAVVWLLLTGSFSPGNLLLGLLLGLLVLLLLRRLL----PPRPPPRRPPLGLLRLLLYFLWEIVKANIQVARLVLRP 76

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 573483785  249 SMPIEPTVTRLEARVGGGLPLLALANSITLTPGTLTVRANDQR--LIVHTL---IPSAREDLFGGSLERAVRFV 317
Cdd:pfam01899  77 KPPIRPGIVAVPLRLRSDLALTLLANSITLTPGTLVVDVDRDRrvLYVHVLdvdDEEAARREIKGRLERRLLEI 150
USP-like cd00293
universal stress protein (USP) and similar proteins; The universal stress protein (USP) is a ...
 6-115 2.13e-03

universal stress protein (USP) and similar proteins; The universal stress protein (USP) is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. USP enhances the rate of cell survival during prolonged exposure to such conditions, and may provide a general "stress endurance" activity. The crystal structure of Haemophilus influenzae Usp reveals an alpha/beta fold similar to that of the Methanococcus jannaschii MJ0577 protein, which binds ATP, although USP lacks ATP-binding activity.


Pssm-ID: 467483 [Multi-domain]  Cd Length: 135  Bit Score: 37.71  E-value: 2.13e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 573483785   6 ILVPLSDTVTVRQTVGYAVQSALEDSDELvcHLVVALP-------QDGTDPTGESSIEEAEQLLERATSWVHEDAgsatV 78
Cdd:cd00293    2 ILVAVDGSEESERALEWALELAKRPGAEL--TLLHVVDpppssslSGGLEELADELKEEAEELLEEAKKLAEEAG----V 75

                         90       100       110
                 ....*....|....*....|....*....|....*..
gi 573483785  79 SVETSILgsteylFGPRqfAEAFVAYADEHGLDCIVL 115
Cdd:cd00293   76 EVETIVV------EGDP--AEAILEEAKELGADLIVM 104
 
Name Accession Description Interval E-value
PRK12652 PRK12652
monovalent cation/H+ antiporter subunit E;
1-341 0e+00

monovalent cation/H+ antiporter subunit E;


Pssm-ID: 237160 [Multi-domain]  Cd Length: 357  Bit Score: 506.21  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 573483785   1 MATNQILVPLSDTVTVRQTVGYAVQSALEDSDELVCHLVVALPQDGTDPTGESSIEEAEQLLERATSWVHEDAG--SATV 78
Cdd:PRK12652   3 MAANRLLVPVADSVTVRQTVAYAVESAEEAAETPTVHLVAAASGRAVDPEGQDELAAAEELLERVEVWATEDLGddASSV 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 573483785  79 SVETSILGSTEYLFGPRQFAEAFVAYADEHGLDCIVLDPEYRPGVTAPMLQPLERELSNVGLEYDEAPVDRPAQHARLVV 158
Cdd:PRK12652  83 TIETALLGTDEYLFGPGDYAEVLIAYAEEHGIDRVVLDPEYNPGGTAPMLQPLERELARAGITYEEAPVERPTRRGRLVR 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 573483785 159 QESFDRMFALFWISYAFYLVLGDPTYWFDLVTGAAVAGIVAVSLSSITFTVAPDRIQSPLRTVRFVLYVPYLAYEIVKAN 238
Cdd:PRK12652 163 AATLDKFAALFGASFGFYLLLGDPLYWFDLLTGAVTALIVAVLLAHVTFSRPPSLRRTPLRVLRFLLYVPYLLWEIVKAN 242

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 573483785 239 LAISVVILRPSMPIEPTVTRLEARVGGGLPLLALANSITLTPGTLTVRANDQRLIVHTLIPSAREDLFGGSLERAVRFVF 318
Cdd:PRK12652 243 VAIAYVILHPSLPIDPTMVRVRAAVRSGLPLTTLANSITLTPGTLTVDVDDRHLLVHSLTPSAREDLFDGGLERAVRFVF 322

                        330       340
                 ....*....|....*....|...
gi 573483785 319 YGRDSASIPTPEERGDAEIVGGD 341
Cdd:PRK12652 323 YGRAAARIPSPAERGDTPDLSVP 345
MnhE COG1863
Multisubunit Na+/H+ antiporter, MnhE subunit [Inorganic ion transport and metabolism];
162-319 5.79e-35

Multisubunit Na+/H+ antiporter, MnhE subunit [Inorganic ion transport and metabolism];


Pssm-ID: 441468  Cd Length: 162  Bit Score: 125.28  E-value: 5.79e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 573483785 162 FDRMFALFWISYAFYLVLGDPTYWFDLVTGAAVAGIVAVslssITFTVAPDRIQSPLRTVRFVLYVPYLAYEIVKANLAI 241
Cdd:COG1863    4 LLPHLLLSLLLALVWLLLSGSFSPGNLLLGLLLALLVLL----LFRRLPPPRLPYLRRPLRLLRLLLYFLWDIVVANIDV 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 573483785 242 SVVILRPSMPIEPTVTRLEARVGGGLPLLALANSITLTPGTLTVRANDQR--LIVHTLIPSAREDL---FGGSLERAVRF 316
Cdd:COG1863   80 ARRVLRPRLPIRPGIVAVPLRLRSDLGITLLANSITLTPGTLTVDVDDDRrtLYVHALDVDDPEALieeIKGRYERRLLE 159


                 ...
gi 573483785 317 VFY 319
Cdd:COG1863  160 IFE 162
MNHE pfam01899
Na+/H+ ion antiporter subunit; Subunit of a Na+/H+ Prokaryotic antiporter complex.
 169-317 1.11e-29

Na+/H+ ion antiporter subunit; Subunit of a Na+/H+ Prokaryotic antiporter complex.


Pssm-ID: 460378  Cd Length: 150  Bit Score: 111.01  E-value: 1.11e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 573483785  169 FWISYAFYLVLGDPTYWFDLVTGAAVAGIVAVSLSSITftvaPDRIQSPLRTVRFVLYVPYLAYEIVKANLAISVVILRP 248
Cdd:pfam01899   1 NLLLAVVWLLLTGSFSPGNLLLGLLLGLLVLLLLRRLL----PPRPPPRRPPLGLLRLLLYFLWEIVKANIQVARLVLRP 76

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 573483785  249 SMPIEPTVTRLEARVGGGLPLLALANSITLTPGTLTVRANDQR--LIVHTL---IPSAREDLFGGSLERAVRFV 317
Cdd:pfam01899  77 KPPIRPGIVAVPLRLRSDLALTLLANSITLTPGTLVVDVDRDRrvLYVHVLdvdDEEAARREIKGRLERRLLEI 150
PRK12651 PRK12651
Na+/H+ antiporter subunit E;
164-318 7.52e-18

Na+/H+ antiporter subunit E;


Pssm-ID: 237159  Cd Length: 158  Bit Score: 79.50  E-value: 7.52e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 573483785 164 RMFALFWISYAFYLVLGDPTYWFDLVTGAaVAGIVAVSLSSITFtvapdRIQSPLRTVRFVL-YVPYLAYEIVKANLAIS 242
Cdd:PRK12651   3 FQLLLNIILAVLWLFLTGSFSLGNFIIGF-ILGLFVLFLFRRLL-----PARFYLRRIYKLIkLVPIFLKELIKANIDVA 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 573483785 243 VVILRPSMPIEPTVTRLEARVGGGLPLLALANSITLTPGTLT--VRANDQRLIVHTL-IPSARE--DLFGGSLERAVRFV 317
Cdd:PRK12651  77 KIVLKPKLNIEPGIVAVPTDLKTDWEITLLANLITLTPGTLTldVSDDRKKLYIHAIdVKDKEEeiREIKDSFEKILLEV 156


                 .
gi 573483785 318 F 318
Cdd:PRK12651 157 F 157
PRK08965 PRK08965
putative monovalent cation/H+ antiporter subunit E; Reviewed
 164-318 2.74e-14

putative monovalent cation/H+ antiporter subunit E; Reviewed


Pssm-ID: 181598  Cd Length: 162  Bit Score: 69.43  E-value: 2.74e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 573483785 164 RMFALFWIS---YAFYLVLGDPTYWFDLVTGAAVAGIVAVSLSSitFTVAPDRIQSPLRTVRFVLYVpylAYEIVKANLA 240
Cdd:PRK08965   4 RLLPQPLLSlwlALVWLLLNGSFSLGNLLLGLLLGLLIPLLLAL--LVPLEGRLRRPLALLRLLLVV---LYDLVVSNIQ 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 573483785 241 ISVVILRPSMPIEPTVTRLEARVGGGLPLLALANSITLTPGTLTVRANDQR--LIVHTL---IPSAREDLFGGSLERAVR 315
Cdd:PRK08965  79 VAWLILRPGPRPRPGFVAVPLRLRSDLALTLLANIITLTPGTVVVEISRDRrtLYVHVLdldDPEALIREIKQRYERLLM 158


                 ...
gi 573483785 316 FVF 318
Cdd:PRK08965 159 EIF 161
PRK06580 PRK06580
putative monovalent cation/H+ antiporter subunit E; Reviewed
 221-315 4.32e-12

putative monovalent cation/H+ antiporter subunit E; Reviewed


Pssm-ID: 180628  Cd Length: 103  Bit Score: 61.81  E-value: 4.32e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 573483785 221 VRFVLYVPYLAYEIVKANLAISVVILRPSMPIEPTVTRLEARVGGGLPLLALANSITLTPGTLTVRANDQRLIVHTLIPS 300
Cdd:PRK06580   7 IKFILYFPWLLLEIWKSAFSVIKIIWQRKIGIEPVFEWVDAEGLEEIGEIIYGNSITLTPGTVTLDINNNMLLVHALNKS 86

                         90
                 ....*....|....*
gi 573483785 301 AREDLFGGSLERAVR 315
Cdd:PRK06580  87 SITDLQRGIMIKKIK 101
PRK08383 PRK08383
putative monovalent cation/H+ antiporter subunit E; Reviewed
 169-315 1.49e-10

putative monovalent cation/H+ antiporter subunit E; Reviewed


Pssm-ID: 181407  Cd Length: 168  Bit Score: 59.05  E-value: 1.49e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 573483785 169 FWISYAFYLVLGDPTYWF-----DLVTGAAVAGIVAVSLSSITFTVApDRIQSPLRTVRFVLY-VPYLAYEIVKANLAIS 242
Cdd:PRK08383   7 FIWSYVLWLVLTAGSKGLlwspeELIAGLIFAAIVGYATRNIIGEKA-TRFLNPIRWLLFIAYaFGPLFWGMVKANLDVA 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 573483785 243 VVILrpSMPIEPTVTRLEARVGGGLPLLALANSITLTPGTLTVRANDQR--LIVHTL-IPSARE-----DLFGGSLERAV 314
Cdd:PRK08383  86 YRVI--TGKIRPGIVKVPVDLENDAQYTILSNSITLTPGTLTIEACPEEkaLYVHWInVPEGLEkpessEPVSGPFEKWA 163


                 .
gi 573483785 315 R 315
Cdd:PRK08383 164 R 164
PRK08382 PRK08382
putative monovalent cation/H+ antiporter subunit E; Reviewed
 166-319 3.14e-06

putative monovalent cation/H+ antiporter subunit E; Reviewed


Pssm-ID: 169415  Cd Length: 201  Bit Score: 47.09  E-value: 3.14e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 573483785 166 FALFWIS-YAFYLVLGDPTYWFDLVTGAAVAGIVAvslsSITFTVAPDRIQSPLRTVR-----FVLYVP-YL---AYEIV 235
Cdd:PRK08382  35 FVLTWLIlLAFWVIISGDLSPRGLILGALTTLIIA----SYMRDFLTEDIRRSGHLLWkilyfALIYLPqYLiimAFRLL 110

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 573483785 236 KANLAISV-VILrpsMPIEPTVTRLEARVGGGLPLLALANSITLTPGTLTV----RANDQRLIVH-----TLIPSAREDL 305
Cdd:PRK08382 111 ESNLKVAKhVIF---MDINPGIVKIKTDLHSDTGITILANSITLTPGTLTLdvvkKLGETYLYVHwidveTLNREKAGEK 187

                        170
                 ....*....|....
gi 573483785 306 FGGSLERAVRFVFY 319
Cdd:PRK08382 188 IKGDIEEWLKKIFW 201
PRK06279 PRK06279
putative monovalent cation/H+ antiporter subunit E; Reviewed
 226-305 5.58e-06

putative monovalent cation/H+ antiporter subunit E; Reviewed


Pssm-ID: 180506 [Multi-domain]  Cd Length: 100  Bit Score: 44.27  E-value: 5.58e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 573483785 226 YVPYLAYEIVKANLAISVVILRPSmpIEPTVTRLEARVGGGLPLLALANSITLTPGTLTVRAN--DQRLIVHTLIPSARE 303
Cdd:PRK06279   9 YLIVLIKAIIEAWIDVVKRSLNGK--IDPEVIEIETEINRPVGQVLLANSITLTPGTLTIDLDseERILKVASISPRSRD 86


                 ..
gi 573483785 304 DL 305
Cdd:PRK06279  87 DI 88
PRK12654 PRK12654
monovalent cation/H+ antiporter subunit E;
224-285 3.42e-04

monovalent cation/H+ antiporter subunit E;


Pssm-ID: 237161  Cd Length: 151  Bit Score: 40.67  E-value: 3.42e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 573483785 224 VLYVPYLAYEIVKANLAISVVILRPSMPIEPTVTRLEARVGGGLPLLALANSITLTPGTLTV 285
Cdd:PRK12654   5 LKYAPWLIGQIFVAGFSLIKDAFKGDKNFNPVVVRYPLRVTKDWQITALAASITATPGTLSL 66
UspA COG0589
Nucleotide-binding universal stress protein, UspA family [Signal transduction mechanisms];
6-115 1.04e-03

Nucleotide-binding universal stress protein, UspA family [Signal transduction mechanisms];


Pssm-ID: 440354  Cd Length: 136  Bit Score: 38.75  E-value: 1.04e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 573483785   6 ILVPLSDTVTVRQTVGYAVQSALEDSDELVChLVVALPQDGTDPTGESSIEEAEQLLERATSWVHEDAGSATVSVETSIL 85
Cdd:COG0589    5 ILVPTDGSEEAERALEYAAELAKALGAELHL-LHVVDPPPSAAAGPEELEEELREEAEEALEEAAERLEEAGVEVETVVR 83

                         90       100       110
                 ....*....|....*....|....*....|
gi 573483785  86 gsteylFGPrqFAEAFVAYADEHGLDCIVL 115
Cdd:COG0589   84 ------EGD--PAEAILEAAEELDADLIVM 105
PRK12596 PRK12596
putative monovalent cation/H+ antiporter subunit E; Reviewed
 197-318 1.15e-03

putative monovalent cation/H+ antiporter subunit E; Reviewed


Pssm-ID: 105779  Cd Length: 171  Bit Score: 39.19  E-value: 1.15e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 573483785 197 IVAVSLSSITFTVAPDR--IQSPlRTVRFVLYVpyLAYEIVKANLAISVVILRPSMPIEPTVTRLEARVGGGLPLLALAN 274
Cdd:PRK12596  34 VIAFGACRVMMALEPQKnhIRSP-RMMIWLLYA--ASIDVLRSNIAVVRLILSPGRQRHPGFVVIPLELQNRTALAVLAC 110

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*....
gi 573483785 275 SITLTPGTLTVRANDQR--LIVHTL---IPSAREDLFGGSLERAVRFVF 318
Cdd:PRK12596 111 MITASPGTAWVDYNAARgiLTIHVLdleDAETWRHLIKERYERPLIEIF 159
USP-like cd00293
universal stress protein (USP) and similar proteins; The universal stress protein (USP) is a ...
 6-115 2.13e-03

universal stress protein (USP) and similar proteins; The universal stress protein (USP) is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. USP enhances the rate of cell survival during prolonged exposure to such conditions, and may provide a general "stress endurance" activity. The crystal structure of Haemophilus influenzae Usp reveals an alpha/beta fold similar to that of the Methanococcus jannaschii MJ0577 protein, which binds ATP, although USP lacks ATP-binding activity.


Pssm-ID: 467483 [Multi-domain]  Cd Length: 135  Bit Score: 37.71  E-value: 2.13e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 573483785   6 ILVPLSDTVTVRQTVGYAVQSALEDSDELvcHLVVALP-------QDGTDPTGESSIEEAEQLLERATSWVHEDAgsatV 78
Cdd:cd00293    2 ILVAVDGSEESERALEWALELAKRPGAEL--TLLHVVDpppssslSGGLEELADELKEEAEELLEEAKKLAEEAG----V 75

                         90       100       110
                 ....*....|....*....|....*....|....*..
gi 573483785  79 SVETSILgsteylFGPRqfAEAFVAYADEHGLDCIVL 115
Cdd:cd00293   76 EVETIVV------EGDP--AEAILEEAKELGADLIVM 104
USP_At3g01520-like cd23659
universal stress protein At3g01520 and similar proteins; This subfamily includes plant and ...
 6-115 2.54e-03

universal stress protein At3g01520 and similar proteins; This subfamily includes plant and fungal proteins of unknown function, including Arabidopsis thaliana At3g01520. A. thaliana contains 44 USP domain-containing proteins; the USP domain is found either in a small protein with unknown physiological function or as an N-terminal portion of a multi-domain protein, usually a protein kinase. The gene At3g01520 of Arabidopsis thaliana encodes a 175-residue universal stress protein (USP)-like protein which is widely found in the genomes of bacteria, as well as fungi, protozoa, and plants. The bound AMP and conservation of residues in the ATP-binding loop suggest that the protein At3g01520 belongs to the ATP-binding USP subfamily. Universal stress proteins (USPs) are small cytoplasmic bacterial proteins whose expression is enhanced when the cell is exposed to stress agents. USP enhances the rate of cell survival during prolonged exposure to such conditions, and may provide a general "stress endurance" activity.


Pssm-ID: 467505  Cd Length: 143  Bit Score: 37.60  E-value: 2.54e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 573483785   6 ILVPLSDTVTVRQTVGYAVQSALEDSDELVC-HlVVALPQDGTDPTG----------ESSIEEAEQLLERATSWVHEDAG 74
Cdd:cd23659    3 VLIAVDGSEESEYALEWALENLHRPGDEVVLlH-VIEPPSLPAASLGsgseewealeEEAREKAEKLLEKYEKKLKEEKG 81

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|.
gi 573483785  75 satVSVETsilgstEYLFGPRqfAEAFVAYADEHGLDCIVL 115
Cdd:cd23659   82 ---IKVKV------EVVAGDP--GEVICKAAEELKADLIVM 111
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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