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Conserved domains on  [gi|573483789|gb|AHG02197|]
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cation:proton antiporter (plasmid) [Halostagnicola larsenii XH-48]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PRK12567 super family cl00676
putative monovalent cation/H+ antiporter subunit B; Reviewed
 1-151 2.28e-48

putative monovalent cation/H+ antiporter subunit B; Reviewed


The actual alignment was detected with superfamily member PRK12505:

Pssm-ID: 469874  Cd Length: 159  Bit Score: 153.81  E-value: 2.28e-48
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 573483789   1 MAERPNDT----YTESQVILTSVKIIAPFTLTYGMFMALHGADSPGGGFQGGAIIGVTILMIAFAFGIEPTRQWLSNSAI 76
Cdd:PRK12505   1 MSDREDTGlrtdYVESTIIMTTVRVVAPFVFTFGLFVMFHGADSPGGGFQGGVIVASVVLMLAFAFGIDATREWLDERLV 80

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 573483789  77 VGLVTGGVAIFVGIGLTTMLLGGDFLEYVRFESALgvpDGGKWSMEAIEIgGITLIVGGVVITLFFAMAAGFTPQ 151
Cdd:PRK12505  81 VAIAVGGVLAFAAIGLGTVLLGGAFLEYHLYPIIH---HASKYGIELVEL-GIGAIVASVIIGLFFLLAAGFGHA 151
 
Name Accession Description Interval E-value
PRK12505 PRK12505
putative monovalent cation/H+ antiporter subunit B; Reviewed
 1-151 2.28e-48

putative monovalent cation/H+ antiporter subunit B; Reviewed


Pssm-ID: 237120  Cd Length: 159  Bit Score: 153.81  E-value: 2.28e-48
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 573483789   1 MAERPNDT----YTESQVILTSVKIIAPFTLTYGMFMALHGADSPGGGFQGGAIIGVTILMIAFAFGIEPTRQWLSNSAI 76
Cdd:PRK12505   1 MSDREDTGlrtdYVESTIIMTTVRVVAPFVFTFGLFVMFHGADSPGGGFQGGVIVASVVLMLAFAFGIDATREWLDERLV 80

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 573483789  77 VGLVTGGVAIFVGIGLTTMLLGGDFLEYVRFESALgvpDGGKWSMEAIEIgGITLIVGGVVITLFFAMAAGFTPQ 151
Cdd:PRK12505  81 VAIAVGGVLAFAAIGLGTVLLGGAFLEYHLYPIIH---HASKYGIELVEL-GIGAIVASVIIGLFFLLAAGFGHA 151
MnhB pfam04039
Domain related to MnhB subunit of Na+/H+ antiporter; Possible subunit of Na+/H+ antiporter,. ...
 14-139 1.26e-25

Domain related to MnhB subunit of Na+/H+ antiporter; Possible subunit of Na+/H+ antiporter,. Predicted integral membrane protein, usually four transmembrane regions in this domain. Often found in bacterial NADH dehydrogenase subunit.


Pssm-ID: 461141 [Multi-domain]  Cd Length: 125  Bit Score: 94.46  E-value: 1.26e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 573483789   14 VILTSVKIIAPFTLTYGMFMALHGADSPGGGFQGGAIIGVTILMIAFAFGIEPTRqWLSNSAIVGLVTGGVAIFVGIGLT 93
Cdd:pfam04039   1 ILRTVARLLFPLILLFSLYLLLRGHNSPGGGFQGGLVAAAALILLYLAFGREELR-RLLPVDPLALEGLGLLLALLTGLL 79

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*.
gi 573483789   94 TMLLGGDFLEYVRFESALGVPDGGKWSMEAIEIGGITLIVGGVVIT 139
Cdd:pfam04039  80 GLLFGGPFLTSAFLYVHLPLLGGVHLGTALLFDIGVYLKVVGGLLL 125
MnhB COG2111
Multisubunit Na+/H+ antiporter, MnhB subunit [Inorganic ion transport and metabolism];
19-104 8.37e-06

Multisubunit Na+/H+ antiporter, MnhB subunit [Inorganic ion transport and metabolism];


Pssm-ID: 441714 [Multi-domain]  Cd Length: 750  Bit Score: 44.70  E-value: 8.37e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 573483789  19 VKIIAPFTLTYGMFMALHGADSPGGGFQGGAIIGVTILMIAFAFGIEPTRQWLSNSAIVgLVTGGVAIFVGIGLTTMLLG 98
Cdd:COG2111  621 TRVLLPGILGFSVYLFFRGHNAPGGGFTGGLVEALALILLYLALGRLWVEERLPVDALI-LIGVGLLLAALTGLAALLFG 699


                 ....*.
gi 573483789  99 GDFLEY 104
Cdd:COG2111  700 GPFLTS 705
 
Name Accession Description Interval E-value
PRK12505 PRK12505
putative monovalent cation/H+ antiporter subunit B; Reviewed
 1-151 2.28e-48

putative monovalent cation/H+ antiporter subunit B; Reviewed


Pssm-ID: 237120  Cd Length: 159  Bit Score: 153.81  E-value: 2.28e-48
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 573483789   1 MAERPNDT----YTESQVILTSVKIIAPFTLTYGMFMALHGADSPGGGFQGGAIIGVTILMIAFAFGIEPTRQWLSNSAI 76
Cdd:PRK12505   1 MSDREDTGlrtdYVESTIIMTTVRVVAPFVFTFGLFVMFHGADSPGGGFQGGVIVASVVLMLAFAFGIDATREWLDERLV 80

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 573483789  77 VGLVTGGVAIFVGIGLTTMLLGGDFLEYVRFESALgvpDGGKWSMEAIEIgGITLIVGGVVITLFFAMAAGFTPQ 151
Cdd:PRK12505  81 VAIAVGGVLAFAAIGLGTVLLGGAFLEYHLYPIIH---HASKYGIELVEL-GIGAIVASVIIGLFFLLAAGFGHA 151
MnhB pfam04039
Domain related to MnhB subunit of Na+/H+ antiporter; Possible subunit of Na+/H+ antiporter,. ...
 14-139 1.26e-25

Domain related to MnhB subunit of Na+/H+ antiporter; Possible subunit of Na+/H+ antiporter,. Predicted integral membrane protein, usually four transmembrane regions in this domain. Often found in bacterial NADH dehydrogenase subunit.


Pssm-ID: 461141 [Multi-domain]  Cd Length: 125  Bit Score: 94.46  E-value: 1.26e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 573483789   14 VILTSVKIIAPFTLTYGMFMALHGADSPGGGFQGGAIIGVTILMIAFAFGIEPTRqWLSNSAIVGLVTGGVAIFVGIGLT 93
Cdd:pfam04039   1 ILRTVARLLFPLILLFSLYLLLRGHNSPGGGFQGGLVAAAALILLYLAFGREELR-RLLPVDPLALEGLGLLLALLTGLL 79

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*.
gi 573483789   94 TMLLGGDFLEYVRFESALGVPDGGKWSMEAIEIGGITLIVGGVVIT 139
Cdd:pfam04039  80 GLLFGGPFLTSAFLYVHLPLLGGVHLGTALLFDIGVYLKVVGGLLL 125
PRK12508 PRK12508
Na(+)/H(+) antiporter subunit B;
14-145 2.40e-18

Na(+)/H(+) antiporter subunit B;


Pssm-ID: 183563  Cd Length: 139  Bit Score: 76.19  E-value: 2.40e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 573483789  14 VILTSVKIIAPFTLTYGMFMALHGADSPGGGFQGGAIIGVTILMIAFAFGIEPTRQWLSNSAIVGLVTGGVAIFVGIGLT 93
Cdd:PRK12508   6 ILRTITKLMIPVIILFGLYVQFHGDYGPGGGFQAGVIVASAIILYSMLFGLSATLKAVPPSFVRLMAALGVLIYGGTGIA 85

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|..
gi 573483789  94 TMLLGGDFLEYvrFESALGVPDGGKWSMEAIEIgGITLIVGGVVITLFFAMA 145
Cdd:PRK12508  86 SMLLGGNFLSY--DVLIFDSVTGQHLGIFLVEL-GVGLTVCSSMLIIYFAFA 134
PRK12507 PRK12507
putative monovalent cation/H+ antiporter subunit B; Reviewed
 3-146 9.40e-18

putative monovalent cation/H+ antiporter subunit B; Reviewed


Pssm-ID: 237121 [Multi-domain]  Cd Length: 332  Bit Score: 78.17  E-value: 9.40e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 573483789   3 ERPNDTYTESQVILTSV-KIIAPFTLTYGMFMALHGADSPGGGFQGGAIIGVTILMIAFAFGIEPTRQWLSNSAIVGLVT 81
Cdd:PRK12507 187 DEGSSGHSQHYPILKYIsKFLIPYIILFSLYVQFHGEFSPGGGFQAGVIFASAIILYAMLYGLRKASRYFPPNVLILIAA 266

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 573483789  82 GGVAIFVGIGLTTMLLGGDFLEYvrfeSALGVPDGGKWSMEAIEI----GGITLIVGGVVITLFFAMAA 146
Cdd:PRK12507 267 LGVAIYAIVGVISLFNGGNFLDY----YSLTNFINDPLLGQHIGIliveIGVGLTVAAIMYLIYNVFAG 331
PRK08387 PRK08387
putative monovalent cation/H+ antiporter subunit B; Reviewed
 12-114 1.53e-13

putative monovalent cation/H+ antiporter subunit B; Reviewed


Pssm-ID: 169420  Cd Length: 131  Bit Score: 63.67  E-value: 1.53e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 573483789  12 SQVILTSVKIIAPFTLTYGMFMALHGADSPGGGFQGGAIIGVTILMIAFAFGIEPTRQWLSNSAIVGLVTGGVAIFVGIG 91
Cdd:PRK08387   2 SLVVRTTTKLVAPFLVTYAAYLMLYGHLSPGGGFQAGVILAVAVILLITSHGYKKVRKRFRKRTVSLLESSSGLFIVGLG 81

                         90       100
                 ....*....|....*....|...
gi 573483789  92 LTTMLLGGDFLEYVRFESALGVP 114
Cdd:PRK08387  82 IAGLLFGLFFLNFLRPSGGIVMP 104
PRK12509 PRK12509
Na+/H+ antiporter subunit B;
14-145 1.52e-09

Na+/H+ antiporter subunit B;


Pssm-ID: 237122 [Multi-domain]  Cd Length: 137  Bit Score: 53.06  E-value: 1.52e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 573483789  14 VIL-TSVKIIAPFTLTYGMFMALHGADSPGGGFQGGAIIGVTILMIAFAFGIEPTRQWLSNSAIvGLVTGGVAIFVGIGL 92
Cdd:PRK12509   4 LILaTASRFLLPLLLLFSVFLLLRGHNEPGGGFIGGLVAAAAFALYLIANGIAAARRLLRVDPL-RLLAAGLLVAVLSGL 82

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|...
gi 573483789  93 TTMLLGGDFLEYVRFEsaLGVPDGGKWSMEAIEIGGITLIVGGVVITLFFAMA 145
Cdd:PRK12509  83 PALFMGLPFLTALWWK--LPLPLIGKVGTPLLFDVGVYLLVLGSTLTIVFSLA 133
PRK12567 PRK12567
putative monovalent cation/H+ antiporter subunit B; Reviewed
 12-98 1.71e-09

putative monovalent cation/H+ antiporter subunit B; Reviewed


Pssm-ID: 237140 [Multi-domain]  Cd Length: 218  Bit Score: 54.52  E-value: 1.71e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 573483789  12 SQVILTSVKIIAPFTLTYGMFMALHGADSPGGGFQGGAIIGVTILMIAFAFGIEPTRQWLSNSAIVGLVTGGVAIFVGIG 91
Cdd:PRK12567  89 DVPLRVLARLLAPFILLFGIYLAIHGHLTPGGGFAAGVAGGTAILLLALSSSPEEMEHIYERWRAKVWEKLAGLVFVLLG 168


                 ....*..
gi 573483789  92 LTTMLLG 98
Cdd:PRK12567 169 LIGLAGG 175
PRK08386 PRK08386
putative monovalent cation/H+ antiporter subunit B; Reviewed
 12-92 6.38e-09

putative monovalent cation/H+ antiporter subunit B; Reviewed


Pssm-ID: 236256  Cd Length: 151  Bit Score: 51.64  E-value: 6.38e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 573483789  12 SQVILTSVKIIAPFTLTYGMFMALHGADSPGGGFQGGAIIGVTILMIAFAFGIEPTRQWLSNSAIVGLVTGGVAIFVGIG 91
Cdd:PRK08386   4 GLIVKTAARAIIPLIGIFGAYIVLHGHLTPGGGFQGGATIAGGGALFLVAFGLDEVKKRFNKTLYSALEGLGGLVFLGAA 83


                 .
gi 573483789  92 L 92
Cdd:PRK08386  84 M 84
PRK06281 PRK06281
putative monovalent cation/H+ antiporter subunit B; Reviewed
 22-102 1.18e-07

putative monovalent cation/H+ antiporter subunit B; Reviewed


Pssm-ID: 180508  Cd Length: 154  Bit Score: 48.60  E-value: 1.18e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 573483789  22 IAPFTLTYGMFMALHGADSPGGGFQGGAIIGVTILMIAFAFGIEPTRQWLSNSAIVGLVTGGVAIFVGIGLTTMLLGGDF 101
Cdd:PRK06281  12 IAIFIMCLGIMTILGGHITPGGGFQGGAMIAAGFILCIVVYGLEKSPFNFSHEFMSIMESFGALGYVGLGLCGLFFSGSF 91


                 .
gi 573483789 102 L 102
Cdd:PRK06281  92 L 92
MnhB COG2111
Multisubunit Na+/H+ antiporter, MnhB subunit [Inorganic ion transport and metabolism];
19-104 8.37e-06

Multisubunit Na+/H+ antiporter, MnhB subunit [Inorganic ion transport and metabolism];


Pssm-ID: 441714 [Multi-domain]  Cd Length: 750  Bit Score: 44.70  E-value: 8.37e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 573483789  19 VKIIAPFTLTYGMFMALHGADSPGGGFQGGAIIGVTILMIAFAFGIEPTRQWLSNSAIVgLVTGGVAIFVGIGLTTMLLG 98
Cdd:COG2111  621 TRVLLPGILGFSVYLFFRGHNAPGGGFTGGLVEALALILLYLALGRLWVEERLPVDALI-LIGVGLLLAALTGLAALLFG 699


                 ....*.
gi 573483789  99 GDFLEY 104
Cdd:COG2111  700 GPFLTS 705
PRK12574 PRK12574
monovalent cation/H+ antiporter subunit B;
11-89 2.12e-05

monovalent cation/H+ antiporter subunit B;


Pssm-ID: 183603 [Multi-domain]  Cd Length: 141  Bit Score: 41.95  E-value: 2.12e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 573483789  11 ESQVILTSV-KIIAPFTLTYGMFMALHGADSPGGGFQGGAIIGVTILMIAFAFGIEPT--------RQWLSNSAIVGLVT 81
Cdd:PRK12574   3 ENDVVLKTVtKIVVFILLTFGFYLFLAGHNNPGGGFIGGLIFSSAFILMFLAFGVEEVleslpidfRKLMIIGLLLSSIT 82


                 ....*...
gi 573483789  82 GGVAIFVG 89
Cdd:PRK12574  83 AIIPMFFG 90
PRK12573 PRK12573
Na(+)/H(+) antiporter subunit B;
14-102 8.58e-05

Na(+)/H(+) antiporter subunit B;


Pssm-ID: 183602 [Multi-domain]  Cd Length: 140  Bit Score: 40.25  E-value: 8.58e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 573483789  14 VIL-TSVKIIAPFTLTYGMFMALHGADSPGGGFQGGAIIGVTILMIAFAFGIEPTRQWL--SNSAIVGLvtgGVAIFVGI 90
Cdd:PRK12573   6 LILrTVAKIVTFIILLFSVFLFLAGHNEPGGGFIGGLITASALVILLLAFDIKTVRRALpfDFKILAGI---GLLFAIAT 82

                         90
                 ....*....|..
gi 573483789  91 GLTTMLLGGDFL 102
Cdd:PRK12573  83 GLASIFFGVPFL 94
PRK12579 PRK12579
putative monovalent cation/H+ antiporter subunit B; Reviewed
 19-102 2.68e-04

putative monovalent cation/H+ antiporter subunit B; Reviewed


Pssm-ID: 183607 [Multi-domain]  Cd Length: 258  Bit Score: 39.70  E-value: 2.68e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 573483789  19 VKIIA-PFT---LTYGMFMALHGADSPGGGFQGGAIIGVTILMIAFAFGIEpTRQWLSNSAIVGLVTGGVAIFVGIGLTT 94
Cdd:PRK12579 112 IKVLAmPMSillMALGIITILGGHITPGGGFQGGALIAAAYILSIVAFGSK-SPLWFKHHFLEKLEAFGALLFMLLGVLG 190


                 ....*...
gi 573483789  95 MLLGGDFL 102
Cdd:PRK12579 191 MFVSGYYL 198
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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