|
Name |
Accession |
Description |
Interval |
E-value |
| PLN02461 |
PLN02461 |
Probable pyruvate kinase |
1-512 |
0e+00 |
|
Probable pyruvate kinase
Pssm-ID: 215255 [Multi-domain] Cd Length: 511 Bit Score: 1097.33 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2277069460 1 MANIDIEGLLKEHLDYEEgRVPKTKIVCTLGPASRSVPMLEKLLRAGMNVARFNFSHGTHEYHQETLNNLRIAMQNTNIL 80
Cdd:PLN02461 1 MANIDIEGILKGLPADGL-RRPKTKIVCTLGPASRSVPMLEKLLRAGMNVARFNFSHGSHEYHQETLDNLRQAMANTGIL 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2277069460 81 SAVMLDTKGPEIRTGFLKDGKPIQLKEGQEITITTDYSIKGDTDTISMSYKKLPVDVKPGNTILCADGTITLTVLSCDPQ 160
Cdd:PLN02461 80 CAVMLDTKGPEIRTGFLKDGKPVQLKQGQEITITTDYSIKGDENMIAMSYKKLAVDVKPGSVILCADGTITLTVLSCDVE 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2277069460 161 AGTVRCRCENTAVLGERKNVNLPGVVVDLPTLTEKDEEDILEWGVPNNIDMIALSFVRKGSDLVHVRKVLGPHAKHIQLM 240
Cdd:PLN02461 160 AGTVRCRCENSAMLGERKNVNLPGVVVDLPTLTEKDKEDILQWGVPNKIDFIALSFVRKGSDLVEVRKVLGEHAKSILLI 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2277069460 241 SKVENQEGVINFDEILRETDSFMVARGDLGMEIPVEKIFLAQKMMIYKCNLVGKPVVTATQMLESMIKSPRPTRAEATDV 320
Cdd:PLN02461 240 SKVENQEGLDNFDDILAESDAFMVARGDLGMEIPIEKIFLAQKMMIYKCNLAGKPVVTATQMLESMIKSPRPTRAEATDV 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2277069460 321 ANAVLDGTDCVMLSGESAAGAYPELAVKIMRRICIEAESSLDYGAIFKDMIRSIPLPMSPLESLASSAVRTANKAKAKLI 400
Cdd:PLN02461 320 ANAVLDGTDCVMLSGETAAGAYPELAVKTMARICREAEASLDYGALFKEIMRSAPLPMSPLESLASSAVRTANKVKASLI 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2277069460 401 VVLTRGGTTAKLVAKYRPAVPILSVVVPVLTTDSFDWACSDETPARHSLIYRGLIPLLAEGSAKATDAESTEVILEAALK 480
Cdd:PLN02461 400 VVLTRGGTTARLVAKYRPAVPILSVVVPEITTDSFDWSCSDEAPARHSLIYRGLIPVLAEGSAKATDSESTEEILEAAIE 479
|
490 500 510
....*....|....*....|....*....|..
gi 2277069460 481 SATARGLCKPGDAVVALHRIGAASVIKICIVK 512
Cdd:PLN02461 480 HAKKKGLCKPGDSVVALHRIGGASVIKILTVK 511
|
|
| Pyruvate_Kinase |
cd00288 |
Pyruvate kinase (PK): Large allosteric enzyme that regulates glycolysis through binding of ... |
22-511 |
0e+00 |
|
Pyruvate kinase (PK): Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low affinity T state. PK exists as several different isozymes, depending on organism and tissue type. In mammals, there are four PK isozymes: R, found in red blood cells, L, found in liver, M1, found in skeletal muscle, and M2, found in kidney, adipose tissue, and lung. PK forms a homotetramer, with each subunit containing three domains. The T state to R state transition of PK is more complex than in most allosteric enzymes, involving a concerted rotation of all 3 domains of each monomer in the homotetramer.
Pssm-ID: 238178 [Multi-domain] Cd Length: 480 Bit Score: 739.13 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2277069460 22 PKTKIVCTLGPASRSVPMLEKLLRAGMNVARFNFSHGTHEYHQETLNNLRIAMQNTNILSAVMLDTKGPEIRTGFLKDGK 101
Cdd:cd00288 2 RRTKIVCTIGPATDSVENLKKLIKAGMNVARMNFSHGSHEYHQSRIDNVREAAEKTGGPVAIALDTKGPEIRTGLFKGGK 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2277069460 102 PIQLKEGQEITITTDYS-IKGDTDTISMSYKKLPVDVKPGNTILCADGTITLTVLSCDPQAgTVRCRCENTAVLGERKNV 180
Cdd:cd00288 82 DISLKAGDKFLVTTDPAaKKGTKEKIYVDYKNLTKDVSPGNTILVDDGLLSLKVLSKDDDK-TLVCEVLNGGVLGSRKGV 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2277069460 181 NLPGVVVDLPTLTEKDEEDILeWGVPNNIDMIALSFVRKGSDLVHVRKVLGPHAKHIQLMSKVENQEGVINFDEILRETD 260
Cdd:cd00288 161 NLPGTDVDLPALSEKDKADLR-FGVEQGVDMIFASFVRKASDVLEIREVLGEKGKDIKIIAKIENQEGVNNFDEILEASD 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2277069460 261 SFMVARGDLGMEIPVEKIFLAQKMMIYKCNLVGKPVVTATQMLESMIKSPRPTRAEATDVANAVLDGTDCVMLSGESAAG 340
Cdd:cd00288 240 GIMVARGDLGVEIPAEEVFLAQKMLIAKCNLAGKPVITATQMLESMIYNPRPTRAEVSDVANAVLDGTDCVMLSGETAKG 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2277069460 341 AYPELAVKIMRRICIEAESSLDYGAIFKDMIRSIPLPMSPLESLASSAVRTANKAKAKLIVVLTRGGTTAKLVAKYRPAV 420
Cdd:cd00288 320 KYPVEAVKAMARICLEAEKALSHRVLFNEMRRLTPRPTSTTEAVAMSAVRAAFELGAKAIVVLTTSGRTARLVSKYRPNA 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2277069460 421 PILSVVVpvlttdsfdwacsDETPARHSLIYRGLIPLLAEgSAKATDAESTEVILEAALKSATARGLCKPGDAVVALHRI 500
Cdd:cd00288 400 PIIAVTR-------------NEQTARQLHLYRGVYPVLFE-EPKPGWQEDTDARLKAAVNVAKEKGLLKKGDLVVVVQGW 465
|
490
....*....|....*
gi 2277069460 501 ----GAASVIKICIV 511
Cdd:cd00288 466 pvgsGSTNTMRILTV 480
|
|
| PykF |
COG0469 |
Pyruvate kinase [Carbohydrate transport and metabolism]; Pyruvate kinase is part of the ... |
23-511 |
0e+00 |
|
Pyruvate kinase [Carbohydrate transport and metabolism]; Pyruvate kinase is part of the Pathway/BioSystem: Glycolysis
Pssm-ID: 440237 [Multi-domain] Cd Length: 471 Bit Score: 620.90 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2277069460 23 KTKIVCTLGPASRSVPMLEKLLRAGMNVARFNFSHGTHEYHQETLNNLRIAMQNTNILSAVMLDTKGPEIRTGFLKDGkP 102
Cdd:COG0469 4 RTKIVATLGPASDSPEVLRKLIEAGMDVARLNFSHGDHEEHRERIELIREAAKELGRPVAILLDLQGPKIRTGKFKEG-P 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2277069460 103 IQLKEGQEITITTDySIKGDTDTISMSYKKLPVDVKPGNTILCADGTITLTVLSCDPQAgtVRCRCENTAVLGERKNVNL 182
Cdd:COG0469 83 VELKKGDTFTLTTD-DVEGDAERVSVTYPELPEDVKPGDRILLDDGKIELRVEEVEGDE--VVCEVVNGGVLSSRKGVNL 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2277069460 183 PGVVVDLPTLTEKDEEDIlEWGVPNNIDMIALSFVRKGSDLVHVRKVLGPHAKHIQLMSKVENQEGVINFDEILRETDSF 262
Cdd:COG0469 160 PGVGLSLPALTEKDREDL-KFALELGVDFIALSFVRSAEDVLEARELLEEAGGRAPIIAKIEKPEAVENLDEIIEASDGI 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2277069460 263 MVARGDLGMEIPVEKIFLAQKMMIYKCNLVGKPVVTATQMLESMIKSPRPTRAEATDVANAVLDGTDCVMLSGESAAGAY 342
Cdd:COG0469 239 MVARGDLGVEIPLEEVPLIQKRIIRKARRAGKPVITATQMLESMIENPRPTRAEVSDVANAVLDGTDAVMLSGETAVGKY 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2277069460 343 PELAVKIMRRICIEAESSLDYGAIFKDmiRSIPLPMSPLESLASSAVRTANKAKAKLIVVLTRGGTTAKLVAKYRPAVPI 422
Cdd:COG0469 319 PVEAVETMARIAEEAEKSLDYRRILDR--LRDEPERTITDAIARAAVELAEDLGAKAIVAFTESGSTARRISRYRPKVPI 396
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2277069460 423 LSVvvpvlttdsfdwaCSDETPARHSLIYRGLIPLLAEgsakatDAESTEVILEAALKSATARGLCKPGDAVV-----AL 497
Cdd:COG0469 397 LAL-------------TPNERTARRLALVWGVYPVLVD------DVESTDEMIEEAVEALLEEGLVKPGDLVVitagvPV 457
|
490
....*....|....
gi 2277069460 498 HRIGAASVIKICIV 511
Cdd:COG0469 458 GVPGTTNTLKVHRV 471
|
|
| PK |
pfam00224 |
Pyruvate kinase, barrel domain; This domain of the is actually a small beta-barrel domain ... |
22-367 |
0e+00 |
|
Pyruvate kinase, barrel domain; This domain of the is actually a small beta-barrel domain nested within a larger TIM barrel. The active site is found in a cleft between the two domains.
Pssm-ID: 395168 [Multi-domain] Cd Length: 348 Bit Score: 583.56 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2277069460 22 PKTKIVCTLGPASRSVPMLEKLLRAGMNVARFNFSHGTHEYHQETLNNLRIAMQNTNILSAVMLDTKGPEIRTGFLKDG- 100
Cdd:pfam00224 2 RRTKIVCTIGPASNSVENLEKLIEAGANVARMNFSHGSHEYHQSRIDNVREAEEKTGGTVAIALDTKGPEIRTGNTKDGk 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2277069460 101 KPIQLKEGQEITITTDYSIKG--DTDTISMSYKKLPVDVKPGNTILCADGTITLTVLSCDPqAGTVRCRCENTAVLGERK 178
Cdd:pfam00224 82 KDIELKAGDEMIVSTDAKYKGacDDEMIYVDYKNIVKDVSVGGTILVDDGLLSLKVLSKDD-DKTLVVEVLNGGVIGSRK 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2277069460 179 NVNLPGVVVDLPTLTEKDEEDIlEWGVPNNIDMIALSFVRKGSDLVHVRKVLGPHAKHIQLMSKVENQEGVINFDEILRE 258
Cdd:pfam00224 161 GVNLPGTDVDLPALSEKDKADL-RFGVKNGVDMIFASFVRKASDVLEIREVLGEAGKNIQIIAKIENQEGVNNFDEILEA 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2277069460 259 TDSFMVARGDLGMEIPVEKIFLAQKMMIYKCNLVGKPVVTATQMLESMIKSPRPTRAEATDVANAVLDGTDCVMLSGESA 338
Cdd:pfam00224 240 TDGIMVARGDLGIEIPAEEVFLAQKMLIAKCNLAGKPVITATQMLESMIYNPRPTRAEVSDVANAVLDGTDCVMLSGETA 319
|
330 340
....*....|....*....|....*....
gi 2277069460 339 AGAYPELAVKIMRRICIEAESSLDYGAIF 367
Cdd:pfam00224 320 KGNYPVEAVRMMHEICLEAEKALPHRNLF 348
|
|
| pyruv_kin |
TIGR01064 |
pyruvate kinase; This enzyme is a homotetramer. Some forms are active only in the presence of ... |
23-505 |
0e+00 |
|
pyruvate kinase; This enzyme is a homotetramer. Some forms are active only in the presence of fructose-1,6-bisphosphate or similar phosphorylated sugars. [Energy metabolism, Glycolysis/gluconeogenesis]
Pssm-ID: 273424 [Multi-domain] Cd Length: 472 Bit Score: 553.04 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2277069460 23 KTKIVCTLGPASRSVPMLEKLLRAGMNVARFNFSHGTHEYHQETLNNLRIAMQNTNILSAVMLDTKGPEIRTGFLKDGkP 102
Cdd:TIGR01064 2 RTKIVCTIGPATNSPEMLKKLLDAGMNVARLNFSHGSHEEHGKRIENVREAAEKLGRPVAILLDTKGPEIRTGEIKGG-E 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2277069460 103 IQLKEGQEITITTDYSIK-GDTDTISMSYKKLPVDVKPGNTILCADGTITLTVLSCDPQagTVRCRCENTAVLGERKNVN 181
Cdd:TIGR01064 81 VKLKKGDKVIITTDDIKGeGDEEKVYVDYKGLTKDVVEGDKILVDDGKISLVVVSVEGD--KVICEVLNGGTLKSKKGVN 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2277069460 182 LPGVVVDLPTLTEKDEEDIlEWGVPNNIDMIALSFVRKGSDLVHVRKVLGPH-AKHIQLMSKVENQEGVINFDEILRETD 260
Cdd:TIGR01064 159 LPGADVDLPALSEKDKKDL-KFGVEQGVDMVAASFVRTAEDVLEVREVLGEKgAKDVKIIAKIENQEGVDNIDEIAEASD 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2277069460 261 SFMVARGDLGMEIPVEKIFLAQKMMIYKCNLVGKPVVTATQMLESMIKSPRPTRAEATDVANAVLDGTDCVMLSGESAAG 340
Cdd:TIGR01064 238 GIMVARGDLGVEIPAEEVPIAQKKMIRKCNRAGKPVITATQMLDSMIKNPRPTRAEVSDVANAVLDGTDAVMLSGETAKG 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2277069460 341 AYPELAVKIMRRICIEAESSLDYGAIFKDMIRSIPLPMSPLESLASSAVRTANKAKAKLIVVLTRGGTTAKLVAKYRPAV 420
Cdd:TIGR01064 318 KYPVEAVQMMAKIAKEAEKALAYLTNFNDRKNSDPKPSTITEAIALSAVEAAEKLDAKAIVVLTESGRTARLLSKYRPNA 397
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2277069460 421 PILSVVVpvlttdsfdwacSDETPARHSLiYRGLIPLLAEGsakatDAESTEVILEAALKSATARGLCKPGDAVVALHRI 500
Cdd:TIGR01064 398 PIIAVTP------------NERVARQLAL-YWGVFPFLVDE-----EPSDTDARVNKALELLKEKGIVKKGDLVVVIQGG 459
|
....*
gi 2277069460 501 GAASV 505
Cdd:TIGR01064 460 PIGGE 464
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PLN02461 |
PLN02461 |
Probable pyruvate kinase |
1-512 |
0e+00 |
|
Probable pyruvate kinase
Pssm-ID: 215255 [Multi-domain] Cd Length: 511 Bit Score: 1097.33 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2277069460 1 MANIDIEGLLKEHLDYEEgRVPKTKIVCTLGPASRSVPMLEKLLRAGMNVARFNFSHGTHEYHQETLNNLRIAMQNTNIL 80
Cdd:PLN02461 1 MANIDIEGILKGLPADGL-RRPKTKIVCTLGPASRSVPMLEKLLRAGMNVARFNFSHGSHEYHQETLDNLRQAMANTGIL 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2277069460 81 SAVMLDTKGPEIRTGFLKDGKPIQLKEGQEITITTDYSIKGDTDTISMSYKKLPVDVKPGNTILCADGTITLTVLSCDPQ 160
Cdd:PLN02461 80 CAVMLDTKGPEIRTGFLKDGKPVQLKQGQEITITTDYSIKGDENMIAMSYKKLAVDVKPGSVILCADGTITLTVLSCDVE 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2277069460 161 AGTVRCRCENTAVLGERKNVNLPGVVVDLPTLTEKDEEDILEWGVPNNIDMIALSFVRKGSDLVHVRKVLGPHAKHIQLM 240
Cdd:PLN02461 160 AGTVRCRCENSAMLGERKNVNLPGVVVDLPTLTEKDKEDILQWGVPNKIDFIALSFVRKGSDLVEVRKVLGEHAKSILLI 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2277069460 241 SKVENQEGVINFDEILRETDSFMVARGDLGMEIPVEKIFLAQKMMIYKCNLVGKPVVTATQMLESMIKSPRPTRAEATDV 320
Cdd:PLN02461 240 SKVENQEGLDNFDDILAESDAFMVARGDLGMEIPIEKIFLAQKMMIYKCNLAGKPVVTATQMLESMIKSPRPTRAEATDV 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2277069460 321 ANAVLDGTDCVMLSGESAAGAYPELAVKIMRRICIEAESSLDYGAIFKDMIRSIPLPMSPLESLASSAVRTANKAKAKLI 400
Cdd:PLN02461 320 ANAVLDGTDCVMLSGETAAGAYPELAVKTMARICREAEASLDYGALFKEIMRSAPLPMSPLESLASSAVRTANKVKASLI 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2277069460 401 VVLTRGGTTAKLVAKYRPAVPILSVVVPVLTTDSFDWACSDETPARHSLIYRGLIPLLAEGSAKATDAESTEVILEAALK 480
Cdd:PLN02461 400 VVLTRGGTTARLVAKYRPAVPILSVVVPEITTDSFDWSCSDEAPARHSLIYRGLIPVLAEGSAKATDSESTEEILEAAIE 479
|
490 500 510
....*....|....*....|....*....|..
gi 2277069460 481 SATARGLCKPGDAVVALHRIGAASVIKICIVK 512
Cdd:PLN02461 480 HAKKKGLCKPGDSVVALHRIGGASVIKILTVK 511
|
|
| Pyruvate_Kinase |
cd00288 |
Pyruvate kinase (PK): Large allosteric enzyme that regulates glycolysis through binding of ... |
22-511 |
0e+00 |
|
Pyruvate kinase (PK): Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low affinity T state. PK exists as several different isozymes, depending on organism and tissue type. In mammals, there are four PK isozymes: R, found in red blood cells, L, found in liver, M1, found in skeletal muscle, and M2, found in kidney, adipose tissue, and lung. PK forms a homotetramer, with each subunit containing three domains. The T state to R state transition of PK is more complex than in most allosteric enzymes, involving a concerted rotation of all 3 domains of each monomer in the homotetramer.
Pssm-ID: 238178 [Multi-domain] Cd Length: 480 Bit Score: 739.13 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2277069460 22 PKTKIVCTLGPASRSVPMLEKLLRAGMNVARFNFSHGTHEYHQETLNNLRIAMQNTNILSAVMLDTKGPEIRTGFLKDGK 101
Cdd:cd00288 2 RRTKIVCTIGPATDSVENLKKLIKAGMNVARMNFSHGSHEYHQSRIDNVREAAEKTGGPVAIALDTKGPEIRTGLFKGGK 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2277069460 102 PIQLKEGQEITITTDYS-IKGDTDTISMSYKKLPVDVKPGNTILCADGTITLTVLSCDPQAgTVRCRCENTAVLGERKNV 180
Cdd:cd00288 82 DISLKAGDKFLVTTDPAaKKGTKEKIYVDYKNLTKDVSPGNTILVDDGLLSLKVLSKDDDK-TLVCEVLNGGVLGSRKGV 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2277069460 181 NLPGVVVDLPTLTEKDEEDILeWGVPNNIDMIALSFVRKGSDLVHVRKVLGPHAKHIQLMSKVENQEGVINFDEILRETD 260
Cdd:cd00288 161 NLPGTDVDLPALSEKDKADLR-FGVEQGVDMIFASFVRKASDVLEIREVLGEKGKDIKIIAKIENQEGVNNFDEILEASD 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2277069460 261 SFMVARGDLGMEIPVEKIFLAQKMMIYKCNLVGKPVVTATQMLESMIKSPRPTRAEATDVANAVLDGTDCVMLSGESAAG 340
Cdd:cd00288 240 GIMVARGDLGVEIPAEEVFLAQKMLIAKCNLAGKPVITATQMLESMIYNPRPTRAEVSDVANAVLDGTDCVMLSGETAKG 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2277069460 341 AYPELAVKIMRRICIEAESSLDYGAIFKDMIRSIPLPMSPLESLASSAVRTANKAKAKLIVVLTRGGTTAKLVAKYRPAV 420
Cdd:cd00288 320 KYPVEAVKAMARICLEAEKALSHRVLFNEMRRLTPRPTSTTEAVAMSAVRAAFELGAKAIVVLTTSGRTARLVSKYRPNA 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2277069460 421 PILSVVVpvlttdsfdwacsDETPARHSLIYRGLIPLLAEgSAKATDAESTEVILEAALKSATARGLCKPGDAVVALHRI 500
Cdd:cd00288 400 PIIAVTR-------------NEQTARQLHLYRGVYPVLFE-EPKPGWQEDTDARLKAAVNVAKEKGLLKKGDLVVVVQGW 465
|
490
....*....|....*
gi 2277069460 501 ----GAASVIKICIV 511
Cdd:cd00288 466 pvgsGSTNTMRILTV 480
|
|
| PykF |
COG0469 |
Pyruvate kinase [Carbohydrate transport and metabolism]; Pyruvate kinase is part of the ... |
23-511 |
0e+00 |
|
Pyruvate kinase [Carbohydrate transport and metabolism]; Pyruvate kinase is part of the Pathway/BioSystem: Glycolysis
Pssm-ID: 440237 [Multi-domain] Cd Length: 471 Bit Score: 620.90 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2277069460 23 KTKIVCTLGPASRSVPMLEKLLRAGMNVARFNFSHGTHEYHQETLNNLRIAMQNTNILSAVMLDTKGPEIRTGFLKDGkP 102
Cdd:COG0469 4 RTKIVATLGPASDSPEVLRKLIEAGMDVARLNFSHGDHEEHRERIELIREAAKELGRPVAILLDLQGPKIRTGKFKEG-P 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2277069460 103 IQLKEGQEITITTDySIKGDTDTISMSYKKLPVDVKPGNTILCADGTITLTVLSCDPQAgtVRCRCENTAVLGERKNVNL 182
Cdd:COG0469 83 VELKKGDTFTLTTD-DVEGDAERVSVTYPELPEDVKPGDRILLDDGKIELRVEEVEGDE--VVCEVVNGGVLSSRKGVNL 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2277069460 183 PGVVVDLPTLTEKDEEDIlEWGVPNNIDMIALSFVRKGSDLVHVRKVLGPHAKHIQLMSKVENQEGVINFDEILRETDSF 262
Cdd:COG0469 160 PGVGLSLPALTEKDREDL-KFALELGVDFIALSFVRSAEDVLEARELLEEAGGRAPIIAKIEKPEAVENLDEIIEASDGI 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2277069460 263 MVARGDLGMEIPVEKIFLAQKMMIYKCNLVGKPVVTATQMLESMIKSPRPTRAEATDVANAVLDGTDCVMLSGESAAGAY 342
Cdd:COG0469 239 MVARGDLGVEIPLEEVPLIQKRIIRKARRAGKPVITATQMLESMIENPRPTRAEVSDVANAVLDGTDAVMLSGETAVGKY 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2277069460 343 PELAVKIMRRICIEAESSLDYGAIFKDmiRSIPLPMSPLESLASSAVRTANKAKAKLIVVLTRGGTTAKLVAKYRPAVPI 422
Cdd:COG0469 319 PVEAVETMARIAEEAEKSLDYRRILDR--LRDEPERTITDAIARAAVELAEDLGAKAIVAFTESGSTARRISRYRPKVPI 396
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2277069460 423 LSVvvpvlttdsfdwaCSDETPARHSLIYRGLIPLLAEgsakatDAESTEVILEAALKSATARGLCKPGDAVV-----AL 497
Cdd:COG0469 397 LAL-------------TPNERTARRLALVWGVYPVLVD------DVESTDEMIEEAVEALLEEGLVKPGDLVVitagvPV 457
|
490
....*....|....
gi 2277069460 498 HRIGAASVIKICIV 511
Cdd:COG0469 458 GVPGTTNTLKVHRV 471
|
|
| PK |
pfam00224 |
Pyruvate kinase, barrel domain; This domain of the is actually a small beta-barrel domain ... |
22-367 |
0e+00 |
|
Pyruvate kinase, barrel domain; This domain of the is actually a small beta-barrel domain nested within a larger TIM barrel. The active site is found in a cleft between the two domains.
Pssm-ID: 395168 [Multi-domain] Cd Length: 348 Bit Score: 583.56 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2277069460 22 PKTKIVCTLGPASRSVPMLEKLLRAGMNVARFNFSHGTHEYHQETLNNLRIAMQNTNILSAVMLDTKGPEIRTGFLKDG- 100
Cdd:pfam00224 2 RRTKIVCTIGPASNSVENLEKLIEAGANVARMNFSHGSHEYHQSRIDNVREAEEKTGGTVAIALDTKGPEIRTGNTKDGk 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2277069460 101 KPIQLKEGQEITITTDYSIKG--DTDTISMSYKKLPVDVKPGNTILCADGTITLTVLSCDPqAGTVRCRCENTAVLGERK 178
Cdd:pfam00224 82 KDIELKAGDEMIVSTDAKYKGacDDEMIYVDYKNIVKDVSVGGTILVDDGLLSLKVLSKDD-DKTLVVEVLNGGVIGSRK 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2277069460 179 NVNLPGVVVDLPTLTEKDEEDIlEWGVPNNIDMIALSFVRKGSDLVHVRKVLGPHAKHIQLMSKVENQEGVINFDEILRE 258
Cdd:pfam00224 161 GVNLPGTDVDLPALSEKDKADL-RFGVKNGVDMIFASFVRKASDVLEIREVLGEAGKNIQIIAKIENQEGVNNFDEILEA 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2277069460 259 TDSFMVARGDLGMEIPVEKIFLAQKMMIYKCNLVGKPVVTATQMLESMIKSPRPTRAEATDVANAVLDGTDCVMLSGESA 338
Cdd:pfam00224 240 TDGIMVARGDLGIEIPAEEVFLAQKMLIAKCNLAGKPVITATQMLESMIYNPRPTRAEVSDVANAVLDGTDCVMLSGETA 319
|
330 340
....*....|....*....|....*....
gi 2277069460 339 AGAYPELAVKIMRRICIEAESSLDYGAIF 367
Cdd:pfam00224 320 KGNYPVEAVRMMHEICLEAEKALPHRNLF 348
|
|
| PTZ00066 |
PTZ00066 |
pyruvate kinase; Provisional |
2-508 |
0e+00 |
|
pyruvate kinase; Provisional
Pssm-ID: 173361 [Multi-domain] Cd Length: 513 Bit Score: 574.79 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2277069460 2 ANIDIEGLLKEhLDYEEGRVPKTKIVCTLGPASRSVPMLEKLLRAGMNVARFNFSHGTHEYHQETLNNLRIAM-QNTNIL 80
Cdd:PTZ00066 19 TNISLDKILEP-ISDNDLRQKKTHIVCTMGPACKNVETLVKLIDAGMNICRFNFSHGDHESHKKTLNNVREAAkARPNAN 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2277069460 81 SAVMLDTKGPEIRTGFLKDGKPIQLKEGQEITITTDYSIKGDTDTISMSYKKLPVDVKPGNTILCADGTITLTVLSCDPQ 160
Cdd:PTZ00066 98 LGILLDTKGPEIRTGFLKNHKPITLKEGQTLKITTDYTFLGDETCISCSYKKLPQSVKVGNIILIADGSLSCKVLEVHDD 177
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2277069460 161 agTVRCRCENTAVLGERKNVNLPGVVVDLPTLTEKDEEDILEWGVPNNIDMIALSFVRKGSDLVHVRKVLGPHAKHIQLM 240
Cdd:PTZ00066 178 --YIITKVLNNATIGERKNMNLPGVKVELPVIGEKDKNDILNFAIPMGCDFIALSFVQSADDVRLCRQLLGERGRHIKII 255
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2277069460 241 SKVENQEGVINFDEILRETDSFMVARGDLGMEIPVEKIFLAQKMMIYKCNLVGKPVVTATQMLESMIKSPRPTRAEATDV 320
Cdd:PTZ00066 256 PKIENIEGLINFDEILAESDGIMVARGDLGMEIPPEKVFLAQKMMISKCNVAGKPVITATQMLESMIKNPRPTRAESTDV 335
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2277069460 321 ANAVLDGTDCVMLSGESAAGAYPELAVKIMRRICIEAESSLDYGAIFKDMIRSIPLPMSPLESLASSAVRTANKAKAKLI 400
Cdd:PTZ00066 336 ANAVLDGTDCVMLSGETANGKFPVEAVNIMAKICFEAETCIDYRVLYHAIHLAVPTPVSVQEAVARSAVETAEDINAKLI 415
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2277069460 401 VVLTRGGTTAKLVAKYRPAVPILsvvvpvlttdsfdwACS-DETPARHSLIYRGLIpllaegSAKATDAESTEVILEAAL 479
Cdd:PTZ00066 416 IALTETGNTARLISKYRPSCTIL--------------ALSaSPSVVKSLSVARGVT------TYVVNSFQGTDVVIRNAI 475
|
490 500 510
....*....|....*....|....*....|....
gi 2277069460 480 KSATARGLCKPGDAVVALHRI-----GAASVIKI 508
Cdd:PTZ00066 476 ALAKERGLVESGDSAIAVHGVkeevaGSSNLMKV 509
|
|
| pyruv_kin |
TIGR01064 |
pyruvate kinase; This enzyme is a homotetramer. Some forms are active only in the presence of ... |
23-505 |
0e+00 |
|
pyruvate kinase; This enzyme is a homotetramer. Some forms are active only in the presence of fructose-1,6-bisphosphate or similar phosphorylated sugars. [Energy metabolism, Glycolysis/gluconeogenesis]
Pssm-ID: 273424 [Multi-domain] Cd Length: 472 Bit Score: 553.04 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2277069460 23 KTKIVCTLGPASRSVPMLEKLLRAGMNVARFNFSHGTHEYHQETLNNLRIAMQNTNILSAVMLDTKGPEIRTGFLKDGkP 102
Cdd:TIGR01064 2 RTKIVCTIGPATNSPEMLKKLLDAGMNVARLNFSHGSHEEHGKRIENVREAAEKLGRPVAILLDTKGPEIRTGEIKGG-E 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2277069460 103 IQLKEGQEITITTDYSIK-GDTDTISMSYKKLPVDVKPGNTILCADGTITLTVLSCDPQagTVRCRCENTAVLGERKNVN 181
Cdd:TIGR01064 81 VKLKKGDKVIITTDDIKGeGDEEKVYVDYKGLTKDVVEGDKILVDDGKISLVVVSVEGD--KVICEVLNGGTLKSKKGVN 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2277069460 182 LPGVVVDLPTLTEKDEEDIlEWGVPNNIDMIALSFVRKGSDLVHVRKVLGPH-AKHIQLMSKVENQEGVINFDEILRETD 260
Cdd:TIGR01064 159 LPGADVDLPALSEKDKKDL-KFGVEQGVDMVAASFVRTAEDVLEVREVLGEKgAKDVKIIAKIENQEGVDNIDEIAEASD 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2277069460 261 SFMVARGDLGMEIPVEKIFLAQKMMIYKCNLVGKPVVTATQMLESMIKSPRPTRAEATDVANAVLDGTDCVMLSGESAAG 340
Cdd:TIGR01064 238 GIMVARGDLGVEIPAEEVPIAQKKMIRKCNRAGKPVITATQMLDSMIKNPRPTRAEVSDVANAVLDGTDAVMLSGETAKG 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2277069460 341 AYPELAVKIMRRICIEAESSLDYGAIFKDMIRSIPLPMSPLESLASSAVRTANKAKAKLIVVLTRGGTTAKLVAKYRPAV 420
Cdd:TIGR01064 318 KYPVEAVQMMAKIAKEAEKALAYLTNFNDRKNSDPKPSTITEAIALSAVEAAEKLDAKAIVVLTESGRTARLLSKYRPNA 397
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2277069460 421 PILSVVVpvlttdsfdwacSDETPARHSLiYRGLIPLLAEGsakatDAESTEVILEAALKSATARGLCKPGDAVVALHRI 500
Cdd:TIGR01064 398 PIIAVTP------------NERVARQLAL-YWGVFPFLVDE-----EPSDTDARVNKALELLKEKGIVKKGDLVVVIQGG 459
|
....*
gi 2277069460 501 GAASV 505
Cdd:TIGR01064 460 PIGGE 464
|
|
| PLN02765 |
PLN02765 |
pyruvate kinase |
24-508 |
0e+00 |
|
pyruvate kinase
Pssm-ID: 215409 [Multi-domain] Cd Length: 526 Bit Score: 530.40 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2277069460 24 TKIVCTLGPASRSVPMLEKLLRAGMNVARFNFSHGTHEYHQETLNNLRIAMQNTNILSAVMLDTKGPEIRTgFLKDGKPI 103
Cdd:PLN02765 30 TKIVGTLGPKSRSVEVIEACLKAGMSVARFDFSWGDAEYHQETLENLKIAVKNTKKLCAVMLDTVGPELQV-INKTEKPI 108
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2277069460 104 QLKEGQEITITTDYSIKGDTDTISMSYKKLPVDVKPGNTILCADGTIT--------LTVLscDPQAGTVRCRCENTAVL- 174
Cdd:PLN02765 109 SLKAGNTVTLTPDQSKEASSEVLPINFPGLAKAVKPGDTIFVGQYLFTgsettsvwLEVD--EVKGDDVVCTVKNSATLa 186
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2277069460 175 GERKNVNLPGVVVDLPTLTEKDEEDILEWGVPNNIDMIALSFVRKGSDLVHVRKVLGPHAKH-IQLMSKVENQEGVINFD 253
Cdd:PLN02765 187 GSLFTLHVSQVRIDLPTLSEKDKEVISTWGVPNKIDFLSLSYTRHAEDVREAREFLSSLGLSqTQIFAKIENVEGLTHFD 266
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2277069460 254 EILRETDSFMVARGDLGMEIPVEKIFLAQKMMIYKCNLVGKPVVTaTQMLESMIKSPRPTRAEATDVANAVLDGTDCVML 333
Cdd:PLN02765 267 EILQEADGIILSRGNLGIDLPPEKVFLFQKAALYKCNMAGKPAVV-TRVVDSMTDNLRPTRAEATDVANAVLDGADAILL 345
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2277069460 334 SGESAAGAYPELAVKIMRRICIEAESSLDYGAIFKDMIRSIPLPMSPLESLASSAVRTANKAKAKLIVVLTRGGTTAKLV 413
Cdd:PLN02765 346 GAETLRGLYPVETISTVGRICAEAEKVFNQDLYFKKTVKYVGEPMSHLESIASSAVRAAIKVKASVIIVFTSSGRAARLI 425
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2277069460 414 AKYRPAVPILSVVVPVLTTDSFDWACSDETPARHSLIYRGLIPLLAEGSAKATDAEST-EVILEAALKSATARGLCKPGD 492
Cdd:PLN02765 426 AKYRPTMPVLSVVIPRLKTNQLKWSFTGAFQARQCLIVRGLFPMLADPRHSAESTSATnESVLKVALDHGKAAGVIKSHD 505
|
490
....*....|....*.
gi 2277069460 493 AVVALHRIGAASVIKI 508
Cdd:PLN02765 506 RVVVCQKVGDSSVVKI 521
|
|
| PRK05826 |
PRK05826 |
pyruvate kinase; Provisional |
23-495 |
0e+00 |
|
pyruvate kinase; Provisional
Pssm-ID: 235619 [Multi-domain] Cd Length: 465 Bit Score: 523.18 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2277069460 23 KTKIVCTLGPASRSVPMLEKLLRAGMNVARFNFSHGTHEYHQETLNNLRIAMQNTNILSAVMLDTKGPEIRTGFLKDGkP 102
Cdd:PRK05826 5 RTKIVATLGPASDSPENLEKLIEAGVNVVRLNFSHGSHEEHGKRAALVREIAAKLGRPVAILLDLKGPKIRVGKFKEG-K 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2277069460 103 IQLKEGQEITITTDYSIKGDTDTISMSYKKLPVDVKPGNTILCADGTITLTVLSCDPQagTVRCRCENTAVLGERKNVNL 182
Cdd:PRK05826 84 ITLKTGDKFTLDTDQKEEGDKERVGVDYKGLPKDVKPGDILLLDDGKLQLKVVEVDGD--EVETEVKNGGPLSNNKGINI 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2277069460 183 PGVVVDLPTLTEKDEEDIlEWGVPNNIDMIALSFVRKGSDLVHVRKVLGPH-AKHIQLMSKVENQEGVINFDEILRETDS 261
Cdd:PRK05826 162 PGGGLSLPALTEKDKADI-KFAAEQGVDYIAVSFVRSAEDVEEARRLLREAgCPHAKIIAKIERAEAVDNIDEIIEASDG 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2277069460 262 FMVARGDLGMEIPVEKIFLAQKMMIYKCNLVGKPVVTATQMLESMIKSPRPTRAEATDVANAVLDGTDCVMLSGESAAGA 341
Cdd:PRK05826 241 IMVARGDLGVEIPDEEVPGLQKKIIRKAREAGKPVITATQMLESMIENPRPTRAEVSDVANAVLDGTDAVMLSGETAAGK 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2277069460 342 YPELAVKIMRRICIEAESSLDYGAIFKDMIRSIplpMSPLESLASSAVRTANKAK-AKLIVVLTRGGTTAKLVAKYRPAV 420
Cdd:PRK05826 321 YPVEAVEAMARICKGAEKEFSINLSKHRLDRQF---DRIDEAIAMSAMYAANHLKgVKAIVALTESGRTARLISRFRPGA 397
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2277069460 421 PILSVvvpvlttdsfdwaCSDETPARHSLIYRGLIPLLAEGSAkatdaeSTEVILEAALKSATARGLCKPGDAVV 495
Cdd:PRK05826 398 PIFAV-------------TRDEKTQRRLALYRGVYPVLFDSAA------DTDDAAEEALRLLLEKGLVESGDLVV 453
|
|
| PRK09206 |
PRK09206 |
pyruvate kinase PykF; |
23-495 |
0e+00 |
|
pyruvate kinase PykF;
Pssm-ID: 181699 [Multi-domain] Cd Length: 470 Bit Score: 517.30 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2277069460 23 KTKIVCTLGPASRSVPMLEKLLRAGMNVARFNFSHGTHEYHQETLNNLRIAMQNTNILSAVMLDTKGPEIRTGFLKDGKP 102
Cdd:PRK09206 3 KTKIVCTIGPKTESEEMLTKLLDAGMNVMRLNFSHGDYAEHGQRIKNLRNVMSKTGKKAAILLDTKGPEIRTMKLEGGND 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2277069460 103 IQLKEGQEITITTDYSIKGDTDTISMSYKKLPVDVKPGNTILCADGTITLTVLSCdpQAGTVRCRCENTAVLGERKNVNL 182
Cdd:PRK09206 83 VSLKAGQTFTFTTDKSVVGNKERVAVTYEGFTADLSVGNTVLVDDGLIGMEVTAI--TGNEVICKVLNNGDLGENKGVNL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2277069460 183 PGVVVDLPTLTEKDEEDiLEWGVPNNIDMIALSFVRKGSDLVHVRKVLGPH-AKHIQLMSKVENQEGVINFDEILRETDS 261
Cdd:PRK09206 161 PGVSIALPALAEKDKQD-LIFGCEQGVDFVAASFIRKRSDVLEIREHLKAHgGENIQIISKIENQEGLNNFDEILEASDG 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2277069460 262 FMVARGDLGMEIPVEKIFLAQKMMIYKCNLVGKPVVTATQMLESMIKSPRPTRAEATDVANAVLDGTDCVMLSGESAAGA 341
Cdd:PRK09206 240 IMVARGDLGVEIPVEEVIFAQKMMIEKCNRARKVVITATQMLDSMIKNPRPTRAEAGDVANAILDGTDAVMLSGESAKGK 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2277069460 342 YPELAVKIMRRICIEAESSLDygaiFKDMIRSIPLPMSPLESLASSAVRTANKAKAKLIVVLTRGGTTAKLVAKYRPAVP 421
Cdd:PRK09206 320 YPLEAVSIMATICERTDRVMN----SRLESNNDNRKLRITEAVCRGAVETAEKLDAPLIVVATQGGKSARSVRKYFPDAT 395
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2277069460 422 ILSvvvpvLTTdsfdwacsDETPARHSLIYRGLIPLLAEGSAkatdaeSTEVILEAALKSATARGLCKPGDAVV 495
Cdd:PRK09206 396 ILA-----LTT--------NEKTARQLVLSKGVVPQLVKEIA------STDDFYRLGKELALQSGLAQKGDVVV 450
|
|
| PRK06354 |
PRK06354 |
pyruvate kinase; Provisional |
23-495 |
1.05e-158 |
|
pyruvate kinase; Provisional
Pssm-ID: 235784 [Multi-domain] Cd Length: 590 Bit Score: 463.63 E-value: 1.05e-158
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2277069460 23 KTKIVCTLGPASRSVPMLEKLLRAGMNVARFNFSHGTHEYHQETLNNLRIAMQNTNILSAVMLDTKGPEIRTGFLKDGkP 102
Cdd:PRK06354 9 RTKIVATIGPASESPEKLRQLIEAGATTARLNFSHGDHEEHGARIKNIREASKKLGKTVGILQDLQGPKIRLGRFEDG-P 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2277069460 103 IQLKEGQEITITTDySIKGDTDTISMSYKKLPVDVKPGNTILCADGTITLTVLSCDPQAGTVRCRCENTAVLGERKNVNL 182
Cdd:PRK06354 88 IELKTGDEFILTSR-EVLGTQEKFSVTYDGLADEVPVGSRILLDDGLIELEVEEVDKADGELHCKVLVGGVLSNKKGVNF 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2277069460 183 PGVVVDLPTLTEKDEEDI---LEWGVpnniDMIALSFVRKGSDLVHVRKVLGPH-AKHIQLMSKVENQEGVINFDEILRE 258
Cdd:PRK06354 167 PGVSLSLPAITEKDREDLifgLEQGV----DWIALSFVRNPSDVLEIRELIEEHnGKHIPIIAKIEKQEAIDNIDAILEL 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2277069460 259 TDSFMVARGDLGMEIPVEKIFLAQKMMIYKCNLVGKPVVTATQMLESMIKSPRPTRAEATDVANAVLDGTDCVMLSGESA 338
Cdd:PRK06354 243 CDGLMVARGDLGVEIPAEEVPLLQKRLIKKANRLGKPVITATQMLDSMQRNPRPTRAEASDVANAILDGTDAVMLSNETA 322
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2277069460 339 AGAYPELAVKIMRRICIEAESSLDYGAIF---KDMIRSIPlpmsplESLASSAVRTANKAKAKLIVVLTRGGTTAKLVAK 415
Cdd:PRK06354 323 AGDYPVEAVQTMATIAVRIEKDLPYRDILskrPEFTTTIT------NAISQAVSHIALQLDAAAIVTLTKSGATARNVSK 396
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2277069460 416 YRPAVPILSVVvpvlttdsfdwacSDETPARH-SLIYrGLIPLLAEgsakatDAESTEVILEAALKSATARGLCKPGDAV 494
Cdd:PRK06354 397 YRPKTPILAVT-------------PNESVARRlQLVW-GVTPLLVL------DAPSTDETFDAAINVAQESGLLKQGDLV 456
|
.
gi 2277069460 495 V 495
Cdd:PRK06354 457 V 457
|
|
| PTZ00300 |
PTZ00300 |
pyruvate kinase; Provisional |
48-498 |
8.27e-144 |
|
pyruvate kinase; Provisional
Pssm-ID: 140321 [Multi-domain] Cd Length: 454 Bit Score: 421.00 E-value: 8.27e-144
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2277069460 48 MNVARFNFSHGTHEYHQETLNNLRIAMQNTNILSAVMLDTKGPEIRTGFLKDGKPIqLKEGQEITITTD--YSIKGDTDT 125
Cdd:PTZ00300 1 MSVARMNFSHGSHEYHQTTINNVRQAAAELGVNIAIALDTKGPEIRTGLFVGGEAV-MERGATCYVTTDpaFADKGTKDK 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2277069460 126 ISMSYKKLPVDVKPGNTILCADGTITLTVLSCDPQAgTVRCRCENTAVLGERKNVNLPGVVVDLPTLTEKDEEDiLEWGV 205
Cdd:PTZ00300 80 FYIDYQNLSKVVRPGGYIYIDDGILILHVQSHEDEQ-TLKCTVTNAHTISDRRGVNLPGCDVDLPAVSAKDCAD-LQFGV 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2277069460 206 PNNIDMIALSFVRKGSDLVHVRKVLGPHAKHIQLMSKVENQEGVINFDEILRETDSFMVARGDLGMEIPVEKIFLAQKMM 285
Cdd:PTZ00300 158 EQGVDMIFASFIRSAEQVGEVRKALGAKGGDIMIICKIENHQGVQNIDSIIEESDGIMVARGDLGVEIPAEKVVVAQKIL 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2277069460 286 IYKCNLVGKPVVTATQMLESMIKSPRPTRAEATDVANAVLDGTDCVMLSGESAAGAYPELAVKIMRRICIEAESSLDYGA 365
Cdd:PTZ00300 238 ISKCNVAGKPVICATQMLESMTYNPRPTRAEVSDVANAVFNGADCVMLSGETAKGKYPNEVVQYMARICLEAQSAVNEYV 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2277069460 366 IFKDMIRSIPLPMSPLESLASSAVRTANKAKAKLIVVLTRGGTTAKLVAKYRPAVPILSVVVPVLTtdsfdwacsdetpA 445
Cdd:PTZ00300 318 FFNSIKKLQPIPMSAEEAVCSSAVNSVYETKAKALVVLSNTGRSARLVAKYRPNCPIVCVTTRLQT-------------C 384
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|...
gi 2277069460 446 RHSLIYRGLIPLLAEGSAKATDaESTEVILEAALKSATARGLCKPGDAVVALH 498
Cdd:PTZ00300 385 RQLNITQGVESVFFDAERLGHD-EGKEQRVAMGVGFAKSKGYVQSGDLMVVVH 436
|
|
| PRK06247 |
PRK06247 |
pyruvate kinase; Provisional |
23-495 |
3.27e-134 |
|
pyruvate kinase; Provisional
Pssm-ID: 180487 [Multi-domain] Cd Length: 476 Bit Score: 396.99 E-value: 3.27e-134
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2277069460 23 KTKIVCTLGPASRSVPMLEKLLRAGMNVARFNFSHGTHEYHQETLNNLRIAMQNTNILSAVMLDTKGPEIRTGFLKDGkP 102
Cdd:PRK06247 6 RVKILATLGPASSSEDMIRKLVEAGADVFRLNFSHGDHDDHRELYKRIREVEDETGRPIGILADLQGPKLRLGRFADG-K 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2277069460 103 IQLKEGQEITITTDySIKGDTDTISMSYKKLPVDVKPGNTILCADGTITLTVLSCDPQAgtVRCRCENTAVLGERKNVNL 182
Cdd:PRK06247 85 VQLANGQTFRLDVD-DAPGDHDRVSLPHPEIAAALKPGDRLLVDDGKVRLVVEACDGDD--VVCRVVEGGPVSDRKGVSL 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2277069460 183 PGVVVDLPTLTEKDEEDiLEWGVPNNIDMIALSFVRKGSDLVHVRKVLGPHAKhiqLMSKVENQEGVINFDEILRETDSF 262
Cdd:PRK06247 162 PGTVLSVSALTEKDRAD-LEFALELGVDWVALSFVQRPEDVEEVRKIIGGRVP---VMAKIEKPQAIDRLEAIVEASDAI 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2277069460 263 MVARGDLGMEIPVEKIFLAQKMMIYKCNLVGKPVVTATQMLESMIKSPRPTRAEATDVANAVLDGTDCVMLSGESAAGAY 342
Cdd:PRK06247 238 MVARGDLGVEVPLEQVPLIQKRIIRAARRAGKPVVVATQMLESMIENPVPTRAEVSDVATAVLDGADAVMLSAETASGKY 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2277069460 343 PELAVKIMRRICIEAESSLDYGAIfkdmirsIPLPMSPLESLASSAV-----RTANKAKAKLIVVLTRGGTTAKLVAKYR 417
Cdd:PRK06247 318 PVEAVRTMARIIRQVERDPTYPPL-------IHAQRPQPEATKRDAIsyaarDIAERLDLAALVAYTSSGDTALRAARER 390
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2277069460 418 PAVPILsVVVPVLTTDSfdwacsdetpaRHSLIYrGLIPLLAEgsakatDAESTEVILEAALKSATARGLCKPGDAVV 495
Cdd:PRK06247 391 PPLPIL-ALTPNPETAR-----------RLALTW-GVHCVVVD------DARDTDDMVRRADRIALAEGFYKRGDRVV 449
|
|
| PLN02623 |
PLN02623 |
pyruvate kinase |
23-494 |
4.53e-102 |
|
pyruvate kinase
Pssm-ID: 215334 [Multi-domain] Cd Length: 581 Bit Score: 318.03 E-value: 4.53e-102
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2277069460 23 KTKIVCTLGPASRSVPMLEKLLRAGMNVARFNFSHGTHEYHQETLNNLR-IAMQNTNILSAVMLDTKGPEIRTGFLKdgK 101
Cdd:PLN02623 111 KTKIVCTIGPSTNTREMIWKLAEAGMNVARLNMSHGDHASHQKVIDLVKeYNAQSKDNVIAIMLDTKGPEVRSGDLP--Q 188
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2277069460 102 PIQLKEGQEITITTDYSIkGDTDTISMSYKKLPVDVKPGNTILCADGTITLTVLScdPQAGTVRCRCENTAVLGERKNVN 181
Cdd:PLN02623 189 PIMLEEGQEFTFTIKRGV-STEDCVSVNYDDFVNDVEVGDMLLVDGGMMSLAVKS--KTSDSVKCEVVDGGELKSRRHLN 265
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2277069460 182 LPGVVVDLPTLTEKDEEDIlEWGVPNNIDMIALSFVrKGSDLVH-VRKVLGPHAKHIQLMSKVENQEGVINFDEILRETD 260
Cdd:PLN02623 266 VRGKSATLPSITEKDWEDI-KFGVENKVDFYAVSFV-KDAQVVHeLKDYLKSCNADIHVIVKIESADSIPNLHSIITASD 343
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2277069460 261 SFMVARGDLGMEIPVEKIFLAQKMMIYKCNLVGKPVVTATQMLESMIKSPRPTRAEATDVANAVLDGTDCVMLSGESAAG 340
Cdd:PLN02623 344 GAMVARGDLGAELPIEEVPLLQEEIIRRCRSMGKPVIVATNMLESMIVHPTPTRAEVSDIAIAVREGADAVMLSGETAHG 423
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2277069460 341 AYPELAVKIMRRICIEAESSLDYGAIFKDMIRSIPLPMSplESLASSAVRTANKAKAKlIVVLTRGGTTAKLVAKYRPAV 420
Cdd:PLN02623 424 KFPLKAVKVMHTVALRTEATLPEGTTPPNLGQAFKNHMS--EMFAFHATMMANTLGTS-IIVFTRTGFMAILLSHYRPSG 500
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2277069460 421 PIlsvvvpvlttdsfdWACSDETPARHSL-IYRGLIPLLAEGSakaTDAESTeviLEAALKSATARGLCKPGDAV 494
Cdd:PLN02623 501 TI--------------FAFTNEKRIQQRLaLYQGVCPIYMQFS---DDAEET---FARALSLLLNKGMVKEGEEV 555
|
|
| PLN02762 |
PLN02762 |
pyruvate kinase complex alpha subunit |
23-507 |
6.36e-90 |
|
pyruvate kinase complex alpha subunit
Pssm-ID: 215407 [Multi-domain] Cd Length: 509 Bit Score: 284.33 E-value: 6.36e-90
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2277069460 23 KTKIVCTLGPASRSVPMLEKLLRAGMNVARFNFSHGTHEYHQETLNNLRIAMQNTNILSAVMLDTKGPEIRTGFLKDGKP 102
Cdd:PLN02762 26 RTKLVCTIGPACCGFEQLEALAMGGMNVARLNMCHGTREWHRDVIRRVRRLNEEKGFAVAVMMDTEGSEIHMGDLGGASS 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2277069460 103 IQLKEGQEITITTDysiKGDTD----TISMSYKKLPVDVKPGNTILCADGTITLTVLscDPQAGTVRCRCENTAVLGERK 178
Cdd:PLN02762 106 AKAEDGEEWTFTVR---KFDGSrpefTIQVNYDGFAEDVKVGDELVVDGGMVRFEVI--EKIGPDVKCKCTDPGLLLPRA 180
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2277069460 179 NVNL--PGVVVD-----LPTLTEKDEEDIlEWGVPNNIDMIALSFVRKGSDLVHVRKVLGPHA--KHIQLMSKVENQEGV 249
Cdd:PLN02762 181 NLTFwrDGSLVRernamLPTISSKDWLDI-DFGISEGVDFIAVSFVKSAEVIKHLKSYIAARSrdSDIGVIAKIESLDSL 259
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2277069460 250 INFDEILRETDSFMVARGDLGMEIPVEKIFLAQKMMIYKCNLVGKPVVTATQMLESMIKSPRPTRAEATDVANAVLDGTD 329
Cdd:PLN02762 260 KNLEEIIRASDGAMVARGDLGAQIPLEQVPSVQEKIVRLCRQLNKPVIVASQLLESMIEYPTPTRAEVADVSEAVRQRAD 339
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2277069460 330 CVMLSGESAAGAYPELAVKIMRRICIEAES----SLDYGAIFKDMIrSIPLPMSPLESLASSAVRTANKAKAKLIVVLTR 405
Cdd:PLN02762 340 ALMLSGESAMGLYPEKALSVLRSVSLRMELwsreEKRHEALELPQL-SSSLSDRISEEICNSAAKMANNLGVDAIFVYTK 418
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2277069460 406 GGTTAKLVAKYRPAVPIlsvvvpvlttdsfdWACSDETPARHSL-IYRGLIPLLAEGSakaTDAESTeviLEAALKSATA 484
Cdd:PLN02762 419 HGHMASLLSRNRPDCPI--------------FAFTDTTSVRRRLnLQWGLIPFRLDFS---DDMESN---LNKTFSLLKA 478
|
490 500
....*....|....*....|...
gi 2277069460 485 RGLCKPGDAVVALHRIGAASVIK 507
Cdd:PLN02762 479 RGMIKSGDLVIAVSDLTPSSMLQ 501
|
|
| PRK06739 |
PRK06739 |
pyruvate kinase; Validated |
27-358 |
3.24e-86 |
|
pyruvate kinase; Validated
Pssm-ID: 180676 [Multi-domain] Cd Length: 352 Bit Score: 269.51 E-value: 3.24e-86
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2277069460 27 VCTLGPASRSVPMLEKLLRAGMNVARFNFSHGTHEYHQETLNNLRIAMQNTNILSavmlDTKGPEIRTGFLKdGKPIQLK 106
Cdd:PRK06739 6 ICTIGPASNNKETLAQLINNGMKIVRLNLSHGTHESHKDIIRLVKSLDDSIKILG----DVQGPKIRLGEIK-GEQITLQ 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2277069460 107 EGQEITITTDySIKGDTDTISMSYKKLPVDVKPGNTILCADGTITLTV--LSCDpqagTVRCRCENTAVLGERKNVNLPG 184
Cdd:PRK06739 81 AGDSFILHTQ-PVTGSSTEASVDYEGIANDVKVGSRILMNDGEVELIVekVSTD----KIETKVKTGGNISSHKGVNLPG 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2277069460 185 VVVDLPTLTEKDEEDIlEWGVPNNIDMIALSFVRKGSDLVHVRKVLGPHAKHI-QLMSKVENQEGVINFDEILRETDSFM 263
Cdd:PRK06739 156 AIVRLPAITEKDKKDI-QFLLEEDVDFIACSFVRKPSHIKEIRDFIQQYKETSpNLIAKIETMEAIENFQDICKEADGIM 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2277069460 264 VARGDLGMEIPVEKIFLAQKMMIYKCNLVGKPVVTATQMLESMIKSPRPTRAEATDVANAVLDGTDCVMLSGESAAGAYP 343
Cdd:PRK06739 235 IARGDLGVELPYQFIPLLQKMMIQECNRTNTYVITATQMLQSMVDHSIPTRAEVTDVFQAVLDGTNAVMLSAESASGEHP 314
|
330
....*....|....*
gi 2277069460 344 ELAVKIMRRICIEAE 358
Cdd:PRK06739 315 IESVSTLRLVSEFAE 329
|
|
| PykA2 |
COG3848 |
Phosphohistidine swiveling domain of PEP-utilizing enzymes [Signal transduction mechanisms]; |
288-495 |
1.26e-42 |
|
Phosphohistidine swiveling domain of PEP-utilizing enzymes [Signal transduction mechanisms];
Pssm-ID: 443058 Cd Length: 321 Bit Score: 154.29 E-value: 1.26e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2277069460 288 KCNLVGKPVVTATQMLESMIKSPRPTRAEATDVANAVLDGTDCVMLSGESAAGAYPELAVKIMRRICIEAESSLDYGAIF 367
Cdd:COG3848 1 KCNAAGKPVITATQMLDSMMRNPRPTRAEAADVANAIFDGTDAIMLSGETAAGKYPVEAVVTMVRIAERAEEDLEYREQR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2277069460 368 KDmiRSIPLPMSPLESLASSAVRTANKAKAKLIVVLTRGGTTAKLVAKYRPAVPILSVvvpvltTDSfdwacsdETPARH 447
Cdd:COG3848 81 VP--RAKESSTTITDAISHAVATTAADLGAAAIITATESGATARMVSKYRPKAPIIAV------TPS-------ERVARQ 145
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 2277069460 448 SLIYRGLIPLLAEgsakatDAESTEVILEAALKSATARGLCKPGDAVV 495
Cdd:COG3848 146 LSLVWGVYPLLVE------ESASTDEMFAVAVALALEAGLVKDGDLVV 187
|
|
| PRK08187 |
PRK08187 |
pyruvate kinase; Validated |
22-353 |
2.77e-39 |
|
pyruvate kinase; Validated
Pssm-ID: 236178 Cd Length: 493 Bit Score: 149.01 E-value: 2.77e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2277069460 22 PKTKIVCTLGPASRSVP--MLEkLLRAGMNVARFNFSHGTHEYHQETLNNLRIAMQNTNILSAVMLDTKGPEIRTG--FL 97
Cdd:PRK08187 133 RRTRIMVTLPSEAADDPdfVLR-LAERGMDCARINCAHDDPAAWQAMIGHLRQAERATGRRCKILMDLAGPKIRTGavAG 211
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2277069460 98 KDGKPiQLKEGQEITITTDYSIKGDTDT---ISMSYKKLPVDVKPGNTILCADGTITLTVLSCDPQAgtVRCRCENTAVL 174
Cdd:PRK08187 212 PLGKT-RLYTGDRLALVAQGPPRRIDEEhfqVTCTLPEILARLAVGARVWIDDGKLGARVERVGPGG--ALLEVTHARPK 288
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2277069460 175 GER----KNVNLPGVVVDLPTLTEKDEEDiLEWgVPNNIDMIALSFVRKGSDLVHVRKVLGPH----AKHIQLMSKVENQ 246
Cdd:PRK08187 289 GLKlkpeKGLNFPDTALDLPALTEKDRAD-LDF-VARHADLVGYSFVQSPGDVEALQAALAARrpddWRKLGLVLKIETP 366
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2277069460 247 EGVINFDEIL-----RETDSFMVARGDLGMEIPVEKIFLAQKMMIYKCNLVGKPVVTATQMLESMIKSPRPTRAEATDVA 321
Cdd:PRK08187 367 RAVANLPELIvqaagRQPFGVMIARGDLAVEIGFERLAEMQEEILWLCEAAHVPVIWATQVLEGLVKKGLPSRAEMTDAA 446
|
330 340 350
....*....|....*....|....*....|..
gi 2277069460 322 NAvlDGTDCVMLSgesaAGAYPELAVKIMRRI 353
Cdd:PRK08187 447 MA--ARAECVMLN----KGPYLVEAVTFLDDL 472
|
|
| PRK14725 |
PRK14725 |
pyruvate kinase; Provisional |
102-353 |
7.95e-29 |
|
pyruvate kinase; Provisional
Pssm-ID: 237804 Cd Length: 608 Bit Score: 120.44 E-value: 7.95e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2277069460 102 PIQLKEGQEITITTDySIKGDTD-------TISMSYKKLPVDVKPGNTILCADGTITLTVLSCDPQAGTVR---CRcENT 171
Cdd:PRK14725 332 KLRLKVGDRLVLTRD-DAPGDPAqgdappaRISCTLPEAFRAARVGERVWFDDGKIGAVVVKVEADEVELRithAR-PGG 409
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2277069460 172 AVLGERKNVNLPGVVVDLPTLTEKDEEDILEwgVPNNIDMIALSFVRKGSDLVHVRKVLGPH-AKHIQLMSKVENQEGVI 250
Cdd:PRK14725 410 SKLKAGKGINLPDSHLPLPALTDKDLEDLAF--VAKHADIVALSFVRSPEDVRLLLDALEKLgADDLGVVLKIETRRAFE 487
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2277069460 251 NFDEILRETDSF-----MVARGDLGMEIPVEKIFLAQKMMIYKCNLVGKPVVTATQMLESMIKSPRPTRAEATDVANAVL 325
Cdd:PRK14725 488 NLPRILLEAMRHprfgvMIARGDLAVEVGFERLAEVQEEILWLCEAAHVPVIWATQVLESLAKKGLPSRAEITDAAMALR 567
|
250 260
....*....|....*....|....*...
gi 2277069460 326 dgTDCVMLSgesaAGAYPELAVKIMRRI 353
Cdd:PRK14725 568 --AECVMLN----KGPHIVEAVRVLDDI 589
|
|
| PK_C |
pfam02887 |
Pyruvate kinase, alpha/beta domain; As well as being found in pyruvate kinase this family is ... |
382-508 |
1.32e-25 |
|
Pyruvate kinase, alpha/beta domain; As well as being found in pyruvate kinase this family is found as an isolated domain in some bacterial proteins.
Pssm-ID: 460738 [Multi-domain] Cd Length: 114 Bit Score: 101.02 E-value: 1.32e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2277069460 382 ESLASSAVRTANKAKAKLIVVLTRGGTTAKLVAKYRPAVPILSVVVPVLTtdsfdwacsdetpARHSLIYRGLIPLLAEg 461
Cdd:pfam02887 1 EAIAHAAVEAAEELGAKAIVVLTESGYTARLISRYRPGVPIIAVTPNELT-------------ARQLALYWGVYPVLFD- 66
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|..
gi 2277069460 462 sakatDAESTEVILEAALKSATARGLCKPGDAVVALHRI-----GAASVIKI 508
Cdd:pfam02887 67 -----EAETTDEMLRRAVKVAKEAGLVKKGDLVVITAGVpfgvsGTTNTLKV 113
|
|
| |
