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Conserved domains on  [gi|2459702587|gb|KAJ6987454|]
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zinc finger CCCH domain-containing protein 37-like [Populus alba x Populus x berolinensis]

Protein Classification

zinc finger CCCH domain-containing protein( domain architecture ID 10457906)

zinc finger CCCH domain-containing protein similar to Homo sapiens proline-rich protein 3 (PRR3)

CATH:  4.10.1000.10
Gene Ontology:  GO:0046872|GO:0003676
PubMed:  12665246|27990022
SCOP:  3001741

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
zf-CCCH pfam00642
Zinc finger C-x8-C-x5-C-x3-H type (and similar);
415-440 2.17e-08

Zinc finger C-x8-C-x5-C-x3-H type (and similar);


:

Pssm-ID: 459885 [Multi-domain]  Cd Length: 27  Bit Score: 49.88  E-value: 2.17e-08
                          10        20
                  ....*....|....*....|....*.
gi 2459702587 415 PGQAECDFYMKTGECKFGETCKFHHP 440
Cdd:pfam00642   1 YKTELCRFFLRTGYCKYGDRCKFAHG 26
zf-CCCH pfam00642
Zinc finger C-x8-C-x5-C-x3-H type (and similar);
253-279 4.79e-08

Zinc finger C-x8-C-x5-C-x3-H type (and similar);


:

Pssm-ID: 459885 [Multi-domain]  Cd Length: 27  Bit Score: 48.73  E-value: 4.79e-08
                          10        20
                  ....*....|....*....|....*..
gi 2459702587 253 PSEPPCAFYMKTGICKFGATCKFHHPK 279
Cdd:pfam00642   1 YKTELCRFFLRTGYCKYGDRCKFAHGQ 27
zf-CCCH pfam00642
Zinc finger C-x8-C-x5-C-x3-H type (and similar);
472-493 1.35e-07

Zinc finger C-x8-C-x5-C-x3-H type (and similar);


:

Pssm-ID: 459885 [Multi-domain]  Cd Length: 27  Bit Score: 47.57  E-value: 1.35e-07
                          10        20
                  ....*....|....*....|..
gi 2459702587 472 CPYYMKTGTCKYGATCKFDHPP 493
Cdd:pfam00642   6 CRFFLRTGYCKYGDRCKFAHGQ 27
zf-CCCH pfam00642
Zinc finger C-x8-C-x5-C-x3-H type (and similar);
333-359 2.52e-07

Zinc finger C-x8-C-x5-C-x3-H type (and similar);


:

Pssm-ID: 459885 [Multi-domain]  Cd Length: 27  Bit Score: 46.80  E-value: 2.52e-07
                          10        20
                  ....*....|....*....|....*..
gi 2459702587 333 PGEVDCPFYLKTGSCKYGATCRYNHPE 359
Cdd:pfam00642   1 YKTELCRFFLRTGYCKYGDRCKFAHGQ 27
zf-CCCH pfam00642
Zinc finger C-x8-C-x5-C-x3-H type (and similar);
207-233 2.38e-06

Zinc finger C-x8-C-x5-C-x3-H type (and similar);


:

Pssm-ID: 459885 [Multi-domain]  Cd Length: 27  Bit Score: 44.11  E-value: 2.38e-06
                          10        20
                  ....*....|....*....|....*..
gi 2459702587 207 PGVPDCPYFLKTQRCKYGVNCKFNHPK 233
Cdd:pfam00642   1 YKTELCRFFLRTGYCKYGDRCKFAHGQ 27
zf-CCCH pfam00642
Zinc finger C-x8-C-x5-C-x3-H type (and similar);
155-181 1.00e-05

Zinc finger C-x8-C-x5-C-x3-H type (and similar);


:

Pssm-ID: 459885 [Multi-domain]  Cd Length: 27  Bit Score: 42.18  E-value: 1.00e-05
                          10        20
                  ....*....|....*....|....*..
gi 2459702587 155 PGEKDCAYYMLTRTCKFGDTCKFDHPV 181
Cdd:pfam00642   1 YKTELCRFFLRTGYCKYGDRCKFAHGQ 27
 
Name Accession Description Interval E-value
zf-CCCH pfam00642
Zinc finger C-x8-C-x5-C-x3-H type (and similar);
415-440 2.17e-08

Zinc finger C-x8-C-x5-C-x3-H type (and similar);


Pssm-ID: 459885 [Multi-domain]  Cd Length: 27  Bit Score: 49.88  E-value: 2.17e-08
                          10        20
                  ....*....|....*....|....*.
gi 2459702587 415 PGQAECDFYMKTGECKFGETCKFHHP 440
Cdd:pfam00642   1 YKTELCRFFLRTGYCKYGDRCKFAHG 26
zf-CCCH pfam00642
Zinc finger C-x8-C-x5-C-x3-H type (and similar);
253-279 4.79e-08

Zinc finger C-x8-C-x5-C-x3-H type (and similar);


Pssm-ID: 459885 [Multi-domain]  Cd Length: 27  Bit Score: 48.73  E-value: 4.79e-08
                          10        20
                  ....*....|....*....|....*..
gi 2459702587 253 PSEPPCAFYMKTGICKFGATCKFHHPK 279
Cdd:pfam00642   1 YKTELCRFFLRTGYCKYGDRCKFAHGQ 27
zf-CCCH pfam00642
Zinc finger C-x8-C-x5-C-x3-H type (and similar);
472-493 1.35e-07

Zinc finger C-x8-C-x5-C-x3-H type (and similar);


Pssm-ID: 459885 [Multi-domain]  Cd Length: 27  Bit Score: 47.57  E-value: 1.35e-07
                          10        20
                  ....*....|....*....|..
gi 2459702587 472 CPYYMKTGTCKYGATCKFDHPP 493
Cdd:pfam00642   6 CRFFLRTGYCKYGDRCKFAHGQ 27
zf-CCCH pfam00642
Zinc finger C-x8-C-x5-C-x3-H type (and similar);
333-359 2.52e-07

Zinc finger C-x8-C-x5-C-x3-H type (and similar);


Pssm-ID: 459885 [Multi-domain]  Cd Length: 27  Bit Score: 46.80  E-value: 2.52e-07
                          10        20
                  ....*....|....*....|....*..
gi 2459702587 333 PGEVDCPFYLKTGSCKYGATCRYNHPE 359
Cdd:pfam00642   1 YKTELCRFFLRTGYCKYGDRCKFAHGQ 27
zf-CCCH pfam00642
Zinc finger C-x8-C-x5-C-x3-H type (and similar);
207-233 2.38e-06

Zinc finger C-x8-C-x5-C-x3-H type (and similar);


Pssm-ID: 459885 [Multi-domain]  Cd Length: 27  Bit Score: 44.11  E-value: 2.38e-06
                          10        20
                  ....*....|....*....|....*..
gi 2459702587 207 PGVPDCPYFLKTQRCKYGVNCKFNHPK 233
Cdd:pfam00642   1 YKTELCRFFLRTGYCKYGDRCKFAHGQ 27
zf-CCCH pfam00642
Zinc finger C-x8-C-x5-C-x3-H type (and similar);
155-181 1.00e-05

Zinc finger C-x8-C-x5-C-x3-H type (and similar);


Pssm-ID: 459885 [Multi-domain]  Cd Length: 27  Bit Score: 42.18  E-value: 1.00e-05
                          10        20
                  ....*....|....*....|....*..
gi 2459702587 155 PGEKDCAYYMLTRTCKFGDTCKFDHPV 181
Cdd:pfam00642   1 YKTELCRFFLRTGYCKYGDRCKFAHGQ 27
ZnF_C3H1 smart00356
zinc finger;
414-440 4.14e-04

zinc finger;


Pssm-ID: 214632 [Multi-domain]  Cd Length: 27  Bit Score: 37.61  E-value: 4.14e-04
                           10        20
                   ....*....|....*....|....*..
gi 2459702587  414 RPGQAECDFYmKTGECKFGETCKFHHP 440
Cdd:smart00356   1 KYKTELCKFF-KRGYCPRGDRCKFAHP 26
ZnF_C3H1 smart00356
zinc finger;
332-359 4.22e-04

zinc finger;


Pssm-ID: 214632 [Multi-domain]  Cd Length: 27  Bit Score: 37.61  E-value: 4.22e-04
                           10        20
                   ....*....|....*....|....*...
gi 2459702587  332 RPGEVDCPFYlKTGSCKYGATCRYNHPE 359
Cdd:smart00356   1 KYKTELCKFF-KRGYCPRGDRCKFAHPL 27
ZnF_C3H1 smart00356
zinc finger;
252-279 8.07e-04

zinc finger;


Pssm-ID: 214632 [Multi-domain]  Cd Length: 27  Bit Score: 36.84  E-value: 8.07e-04
                           10        20
                   ....*....|....*....|....*...
gi 2459702587  252 RPSEPPCAFYmKTGICKFGATCKFHHPK 279
Cdd:smart00356   1 KYKTELCKFF-KRGYCPRGDRCKFAHPL 27
ZnF_C3H1 smart00356
zinc finger;
206-233 1.43e-03

zinc finger;


Pssm-ID: 214632 [Multi-domain]  Cd Length: 27  Bit Score: 36.07  E-value: 1.43e-03
                           10        20
                   ....*....|....*....|....*...
gi 2459702587  206 RPGVPDCPYFlKTQRCKYGVNCKFNHPK 233
Cdd:smart00356   1 KYKTELCKFF-KRGYCPRGDRCKFAHPL 27
ZnF_C3H1 smart00356
zinc finger;
472-493 1.50e-03

zinc finger;


Pssm-ID: 214632 [Multi-domain]  Cd Length: 27  Bit Score: 36.07  E-value: 1.50e-03
                           10        20
                   ....*....|....*....|..
gi 2459702587  472 CPYYmKTGTCKYGATCKFDHPP 493
Cdd:smart00356   7 CKFF-KRGYCPRGDRCKFAHPL 27
 
Name Accession Description Interval E-value
zf-CCCH pfam00642
Zinc finger C-x8-C-x5-C-x3-H type (and similar);
415-440 2.17e-08

Zinc finger C-x8-C-x5-C-x3-H type (and similar);


Pssm-ID: 459885 [Multi-domain]  Cd Length: 27  Bit Score: 49.88  E-value: 2.17e-08
                          10        20
                  ....*....|....*....|....*.
gi 2459702587 415 PGQAECDFYMKTGECKFGETCKFHHP 440
Cdd:pfam00642   1 YKTELCRFFLRTGYCKYGDRCKFAHG 26
zf-CCCH pfam00642
Zinc finger C-x8-C-x5-C-x3-H type (and similar);
253-279 4.79e-08

Zinc finger C-x8-C-x5-C-x3-H type (and similar);


Pssm-ID: 459885 [Multi-domain]  Cd Length: 27  Bit Score: 48.73  E-value: 4.79e-08
                          10        20
                  ....*....|....*....|....*..
gi 2459702587 253 PSEPPCAFYMKTGICKFGATCKFHHPK 279
Cdd:pfam00642   1 YKTELCRFFLRTGYCKYGDRCKFAHGQ 27
zf-CCCH pfam00642
Zinc finger C-x8-C-x5-C-x3-H type (and similar);
472-493 1.35e-07

Zinc finger C-x8-C-x5-C-x3-H type (and similar);


Pssm-ID: 459885 [Multi-domain]  Cd Length: 27  Bit Score: 47.57  E-value: 1.35e-07
                          10        20
                  ....*....|....*....|..
gi 2459702587 472 CPYYMKTGTCKYGATCKFDHPP 493
Cdd:pfam00642   6 CRFFLRTGYCKYGDRCKFAHGQ 27
zf-CCCH pfam00642
Zinc finger C-x8-C-x5-C-x3-H type (and similar);
333-359 2.52e-07

Zinc finger C-x8-C-x5-C-x3-H type (and similar);


Pssm-ID: 459885 [Multi-domain]  Cd Length: 27  Bit Score: 46.80  E-value: 2.52e-07
                          10        20
                  ....*....|....*....|....*..
gi 2459702587 333 PGEVDCPFYLKTGSCKYGATCRYNHPE 359
Cdd:pfam00642   1 YKTELCRFFLRTGYCKYGDRCKFAHGQ 27
zf-CCCH pfam00642
Zinc finger C-x8-C-x5-C-x3-H type (and similar);
207-233 2.38e-06

Zinc finger C-x8-C-x5-C-x3-H type (and similar);


Pssm-ID: 459885 [Multi-domain]  Cd Length: 27  Bit Score: 44.11  E-value: 2.38e-06
                          10        20
                  ....*....|....*....|....*..
gi 2459702587 207 PGVPDCPYFLKTQRCKYGVNCKFNHPK 233
Cdd:pfam00642   1 YKTELCRFFLRTGYCKYGDRCKFAHGQ 27
zf-CCCH pfam00642
Zinc finger C-x8-C-x5-C-x3-H type (and similar);
155-181 1.00e-05

Zinc finger C-x8-C-x5-C-x3-H type (and similar);


Pssm-ID: 459885 [Multi-domain]  Cd Length: 27  Bit Score: 42.18  E-value: 1.00e-05
                          10        20
                  ....*....|....*....|....*..
gi 2459702587 155 PGEKDCAYYMLTRTCKFGDTCKFDHPV 181
Cdd:pfam00642   1 YKTELCRFFLRTGYCKYGDRCKFAHGQ 27
ZnF_C3H1 smart00356
zinc finger;
414-440 4.14e-04

zinc finger;


Pssm-ID: 214632 [Multi-domain]  Cd Length: 27  Bit Score: 37.61  E-value: 4.14e-04
                           10        20
                   ....*....|....*....|....*..
gi 2459702587  414 RPGQAECDFYmKTGECKFGETCKFHHP 440
Cdd:smart00356   1 KYKTELCKFF-KRGYCPRGDRCKFAHP 26
ZnF_C3H1 smart00356
zinc finger;
332-359 4.22e-04

zinc finger;


Pssm-ID: 214632 [Multi-domain]  Cd Length: 27  Bit Score: 37.61  E-value: 4.22e-04
                           10        20
                   ....*....|....*....|....*...
gi 2459702587  332 RPGEVDCPFYlKTGSCKYGATCRYNHPE 359
Cdd:smart00356   1 KYKTELCKFF-KRGYCPRGDRCKFAHPL 27
ZnF_C3H1 smart00356
zinc finger;
252-279 8.07e-04

zinc finger;


Pssm-ID: 214632 [Multi-domain]  Cd Length: 27  Bit Score: 36.84  E-value: 8.07e-04
                           10        20
                   ....*....|....*....|....*...
gi 2459702587  252 RPSEPPCAFYmKTGICKFGATCKFHHPK 279
Cdd:smart00356   1 KYKTELCKFF-KRGYCPRGDRCKFAHPL 27
ZnF_C3H1 smart00356
zinc finger;
206-233 1.43e-03

zinc finger;


Pssm-ID: 214632 [Multi-domain]  Cd Length: 27  Bit Score: 36.07  E-value: 1.43e-03
                           10        20
                   ....*....|....*....|....*...
gi 2459702587  206 RPGVPDCPYFlKTQRCKYGVNCKFNHPK 233
Cdd:smart00356   1 KYKTELCKFF-KRGYCPRGDRCKFAHPL 27
ZnF_C3H1 smart00356
zinc finger;
472-493 1.50e-03

zinc finger;


Pssm-ID: 214632 [Multi-domain]  Cd Length: 27  Bit Score: 36.07  E-value: 1.50e-03
                           10        20
                   ....*....|....*....|..
gi 2459702587  472 CPYYmKTGTCKYGATCKFDHPP 493
Cdd:smart00356   7 CKFF-KRGYCPRGDRCKFAHPL 27
zf_CCCH_4 pfam18345
Zinc finger domain; This is a zinc finger domain found in Zinc finger CCCH-type with G patch ...
 472-491 2.01e-03

Zinc finger domain; This is a zinc finger domain found in Zinc finger CCCH-type with G patch domain-containing proteins such as ZIP. Functional studies indicate that ZIP specifically targets EGFR and represses its transcription, and that the zinc finger and the coiled-coil domains are central to that process.


Pssm-ID: 465719 [Multi-domain]  Cd Length: 19  Bit Score: 35.47  E-value: 2.01e-03
                          10        20
                  ....*....|....*....|
gi 2459702587 472 CPYYMKtGTCKYGATCKFDH 491
Cdd:pfam18345   1 CKFFLK-GRCRYGDKCRFAH 19
zf_CCCH_4 pfam18345
Zinc finger domain; This is a zinc finger domain found in Zinc finger CCCH-type with G patch ...
 338-357 8.67e-03

Zinc finger domain; This is a zinc finger domain found in Zinc finger CCCH-type with G patch domain-containing proteins such as ZIP. Functional studies indicate that ZIP specifically targets EGFR and represses its transcription, and that the zinc finger and the coiled-coil domains are central to that process.


Pssm-ID: 465719 [Multi-domain]  Cd Length: 19  Bit Score: 33.93  E-value: 8.67e-03
                          10        20
                  ....*....|....*....|
gi 2459702587 338 CPFYLKtGSCKYGATCRYNH 357
Cdd:pfam18345   1 CKFFLK-GRCRYGDKCRFAH 19
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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