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Conserved domains on  [gi|62078839|ref|NP_001014075|]
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leucine-rich repeat-containing protein 26 precursor [Rattus norvegicus]

Protein Classification

leucine-rich repeat domain-containing protein( domain architecture ID 11469232)

leucine-rich repeat (LRR) domain-containing protein may participate in protein-protein interactions

Gene Ontology:  GO:0005515
PubMed:  11751054|7583641|14747988
SCOP:  4003523

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
76-205 2.55e-14

Leucine-rich repeat (LRR) protein [Transcription];


:

Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 73.43  E-value: 2.55e-14
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62078839  76 QVRSLLLDRNRVSTLPPgAFADAGALLYLVLRENRLRSVHArAFWGLGVLQRLDLSSNQLETLsPGTFTPLRALSFLSLA 155
Cdd:COG4886 114 NLESLDLSGNQLTDLPE-ELANLTNLKELDLSNNQLTDLPE-PLGNLTNLKSLDLSNNQLTDL-PEELGNLTNLKELDLS 190

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|
gi 62078839 156 GNRLALLePSILGPLPLLRVLSLQDNSLSALEAGLLNsLPALDVLRLHGN 205
Cdd:COG4886 191 NNQITDL-PEPLGNLTNLEELDLSGNQLTDLPEPLAN-LTNLETLDLSNN 238
PCC super family cl28216
polycystin cation channel protein; The Polycystin Cation Channel (PCC) Family (TC 1.A.5) ...
 178-295 5.16e-05

polycystin cation channel protein; The Polycystin Cation Channel (PCC) Family (TC 1.A.5) Polycystin is a huge protein of 4303aas. Its repeated leucine-rich (LRR) segment is found in many proteins. It contains 16 polycystic kidney disease (PKD) domains, one LDL-receptor class A domain, one C-type lectin family domain, and 16-18 putative TMSs in positions between residues 2200 and 4100. Polycystin-L has been shown to be a cation (Na+, K+ and Ca2+) channel that is activated by Ca2+. Two members of the PCC family (polycystin 1 and 2) are mutated in autosomal dominant polycystic kidney disease, and polycystin-L is deleted in mice with renal and retinal defects. Note: this model is restricted to the amino half.


The actual alignment was detected with superfamily member TIGR00864:

Pssm-ID: 188093 [Multi-domain]  Cd Length: 2740  Bit Score: 45.07  E-value: 5.16e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62078839    178 LQDNSLSALEAGLLNSLPALDVLRLHGNPWACSCALRPLCTWLRKHPRPTSETETLLCVSP------KLQTLNLLTDFPD 251
Cdd:TIGR00864    2 ISNNKISTIEEGICANLCNLSEIDLSGNPFECDCGLARLPRWAEEKGVKVRQPEAALCAGPgalagqPLLGIPLLDSGCD 81

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|..
gi 62078839    252 NAFKQC-----TQSLAARDLAVVYALGPASFL---ASLAICLALGSVLTACG 295
Cdd:TIGR00864   82 EEYVAClkdnsSGGGAARSELVIFSAAHEGLFqpeACNAFCFSAGHGLAALG 133
 
Name Accession Description Interval E-value
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
76-205 2.55e-14

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 73.43  E-value: 2.55e-14
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62078839  76 QVRSLLLDRNRVSTLPPgAFADAGALLYLVLRENRLRSVHArAFWGLGVLQRLDLSSNQLETLsPGTFTPLRALSFLSLA 155
Cdd:COG4886 114 NLESLDLSGNQLTDLPE-ELANLTNLKELDLSNNQLTDLPE-PLGNLTNLKSLDLSNNQLTDL-PEELGNLTNLKELDLS 190

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|
gi 62078839 156 GNRLALLePSILGPLPLLRVLSLQDNSLSALEAGLLNsLPALDVLRLHGN 205
Cdd:COG4886 191 NNQITDL-PEPLGNLTNLEELDLSGNQLTDLPEPLAN-LTNLETLDLSNN 238
LRR_8 pfam13855
Leucine rich repeat;
76-135 1.75e-13

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 64.47  E-value: 1.75e-13
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 62078839    76 QVRSLLLDRNRVSTLPPGAFADAGALLYLVLRENRLRSVHARAFWGLGVLQRLDLSSNQL 135
Cdd:pfam13855   2 NLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
PRK15370 PRK15370
type III secretion system effector E3 ubiquitin transferase SlrP;
64-252 1.05e-08

type III secretion system effector E3 ubiquitin transferase SlrP;


Pssm-ID: 185268 [Multi-domain]  Cd Length: 754  Bit Score: 56.63  E-value: 1.05e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62078839   64 LALPAVPAGLSWQVRSLLLDRNRVSTLPPGAFADagaLLYLVLRENRLRSVHARAfwgLGVLQRLDLSSNQLETLspgtf 143
Cdd:PRK15370 188 LGLTTIPACIPEQITTLILDNNELKSLPENLQGN---IKTLYANSNQLTSIPATL---PDTIQEMELSINRITEL----- 256

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62078839  144 tPLR---ALSFLSLAGNRLALLEPSilgpLPL-LRVLSLQDNSLSALEAGL-------------LNSLPA-----LDVLR 201
Cdd:PRK15370 257 -PERlpsALQSLDLFHNKISCLPEN----LPEeLRYLSVYDNSIRTLPAHLpsgithlnvqsnsLTALPEtlppgLKTLE 331

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 62078839  202 LHGNPWAC-SCALRPLCTWLR-KHPRPTSETETLlcvSPKLQTL----NLLTDFPDN 252
Cdd:PRK15370 332 AGENALTSlPASLPPELQVLDvSKNQITVLPETL---PPTITTLdvsrNALTNLPEN 385
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 125-206 1.30e-05

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 45.55  E-value: 1.30e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62078839 125 LQRLDLSSNQLETLSPgtftplralsflslagnrlallepsiLGPLPLLRVLSLQDNSLSALE--AGLLNSLPALDVLRL 202
Cdd:cd21340 122 LRVLNISGNNIDSLEP--------------------------LAPLRNLEQLDASNNQISDLEelLDLLSSWPSLRELDL 175


                ....
gi 62078839 203 HGNP 206
Cdd:cd21340 176 TGNP 179
PCC TIGR00864
polycystin cation channel protein; The Polycystin Cation Channel (PCC) Family (TC 1.A.5) ...
 178-295 5.16e-05

polycystin cation channel protein; The Polycystin Cation Channel (PCC) Family (TC 1.A.5) Polycystin is a huge protein of 4303aas. Its repeated leucine-rich (LRR) segment is found in many proteins. It contains 16 polycystic kidney disease (PKD) domains, one LDL-receptor class A domain, one C-type lectin family domain, and 16-18 putative TMSs in positions between residues 2200 and 4100. Polycystin-L has been shown to be a cation (Na+, K+ and Ca2+) channel that is activated by Ca2+. Two members of the PCC family (polycystin 1 and 2) are mutated in autosomal dominant polycystic kidney disease, and polycystin-L is deleted in mice with renal and retinal defects. Note: this model is restricted to the amino half.


Pssm-ID: 188093 [Multi-domain]  Cd Length: 2740  Bit Score: 45.07  E-value: 5.16e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62078839    178 LQDNSLSALEAGLLNSLPALDVLRLHGNPWACSCALRPLCTWLRKHPRPTSETETLLCVSP------KLQTLNLLTDFPD 251
Cdd:TIGR00864    2 ISNNKISTIEEGICANLCNLSEIDLSGNPFECDCGLARLPRWAEEKGVKVRQPEAALCAGPgalagqPLLGIPLLDSGCD 81

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|..
gi 62078839    252 NAFKQC-----TQSLAARDLAVVYALGPASFL---ASLAICLALGSVLTACG 295
Cdd:TIGR00864   82 EEYVAClkdnsSGGGAARSELVIFSAAHEGLFqpeACNAFCFSAGHGLAALG 133
LRRCT smart00082
Leucine rich repeat C-terminal domain;
205-258 8.59e-04

Leucine rich repeat C-terminal domain;


Pssm-ID: 214507 [Multi-domain]  Cd Length: 51  Bit Score: 36.64  E-value: 8.59e-04
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....
gi 62078839    205 NPWACSCALRPLCTWLRKHPRpTSETETLLCVSPKLQTLNLLTDfpDNAFKQCT 258
Cdd:smart00082   1 NPFICDCELRWLLRWLQANEH-LQDPVDLRCASPSSLRGPLLEL--LHSEFKCP 51
 
Name Accession Description Interval E-value
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
76-205 2.55e-14

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 73.43  E-value: 2.55e-14
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62078839  76 QVRSLLLDRNRVSTLPPgAFADAGALLYLVLRENRLRSVHArAFWGLGVLQRLDLSSNQLETLsPGTFTPLRALSFLSLA 155
Cdd:COG4886 114 NLESLDLSGNQLTDLPE-ELANLTNLKELDLSNNQLTDLPE-PLGNLTNLKSLDLSNNQLTDL-PEELGNLTNLKELDLS 190

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|
gi 62078839 156 GNRLALLePSILGPLPLLRVLSLQDNSLSALEAGLLNsLPALDVLRLHGN 205
Cdd:COG4886 191 NNQITDL-PEPLGNLTNLEELDLSGNQLTDLPEPLAN-LTNLETLDLSNN 238
LRR_8 pfam13855
Leucine rich repeat;
76-135 1.75e-13

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 64.47  E-value: 1.75e-13
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 62078839    76 QVRSLLLDRNRVSTLPPGAFADAGALLYLVLRENRLRSVHARAFWGLGVLQRLDLSSNQL 135
Cdd:pfam13855   2 NLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
LRR_8 pfam13855
Leucine rich repeat;
103-159 1.09e-12

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 62.16  E-value: 1.09e-12
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 62078839   103 YLVLRENRLRSVHARAFWGLGVLQRLDLSSNQLETLSPGTFTPLRALSFLSLAGNRL 159
Cdd:pfam13855   5 SLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
94-205 2.73e-11

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 64.18  E-value: 2.73e-11
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62078839  94 AFADAGALLYLVLRENRLRSVhARAFWGLGVLQRLDLSSNQLETLsPGTFTPLRALSFLSLAGNRLALLePSILGPLPLL 173
Cdd:COG4886 108 ELSNLTNLESLDLSGNQLTDL-PEELANLTNLKELDLSNNQLTDL-PEPLGNLTNLKSLDLSNNQLTDL-PEELGNLTNL 184

                        90       100       110
                ....*....|....*....|....*....|..
gi 62078839 174 RVLSLQDNSLSALEAGLLNsLPALDVLRLHGN 205
Cdd:COG4886 185 KELDLSNNQITDLPEPLGN-LTNLEELDLSGN 215
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
110-206 4.21e-10

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 60.33  E-value: 4.21e-10
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62078839 110 RLRSVHARAFWGLGVLQRLDLSSNQLETLsPGTFTPLRALSFLSLAGNRLALLePSILGPLPLLRVLSLQDNSLSALEAG 189
Cdd:COG4886 100 ELDLSGNEELSNLTNLESLDLSGNQLTDL-PEELANLTNLKELDLSNNQLTDL-PEPLGNLTNLKSLDLSNNQLTDLPEE 177

                        90
                ....*....|....*..
gi 62078839 190 LLNsLPALDVLRLHGNP 206
Cdd:COG4886 178 LGN-LTNLKELDLSNNQ 193
PRK15370 PRK15370
type III secretion system effector E3 ubiquitin transferase SlrP;
64-252 1.05e-08

type III secretion system effector E3 ubiquitin transferase SlrP;


Pssm-ID: 185268 [Multi-domain]  Cd Length: 754  Bit Score: 56.63  E-value: 1.05e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62078839   64 LALPAVPAGLSWQVRSLLLDRNRVSTLPPGAFADagaLLYLVLRENRLRSVHARAfwgLGVLQRLDLSSNQLETLspgtf 143
Cdd:PRK15370 188 LGLTTIPACIPEQITTLILDNNELKSLPENLQGN---IKTLYANSNQLTSIPATL---PDTIQEMELSINRITEL----- 256

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62078839  144 tPLR---ALSFLSLAGNRLALLEPSilgpLPL-LRVLSLQDNSLSALEAGL-------------LNSLPA-----LDVLR 201
Cdd:PRK15370 257 -PERlpsALQSLDLFHNKISCLPEN----LPEeLRYLSVYDNSIRTLPAHLpsgithlnvqsnsLTALPEtlppgLKTLE 331

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 62078839  202 LHGNPWAC-SCALRPLCTWLR-KHPRPTSETETLlcvSPKLQTL----NLLTDFPDN 252
Cdd:PRK15370 332 AGENALTSlPASLPPELQVLDvSKNQITVLPETL---PPTITTLdvsrNALTNLPEN 385
LRR_8 pfam13855
Leucine rich repeat;
125-183 4.15e-08

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 49.06  E-value: 4.15e-08
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 62078839   125 LQRLDLSSNQLETLSPGTFTPLRALSFLSLAGNRLALLEPSILGPLPLLRVLSLQDNSL 183
Cdd:pfam13855   3 LRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 74-224 5.06e-06

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 48.31  E-value: 5.06e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62078839   74 SWQVRSLLLDRNRVSTLPPGAFADAGALLYLVLRENRLRSVHARAFWGLGVLQRLDLSSNQLETLSPGTFTPLRALSFLS 153
Cdd:PLN00113 474 SKRLENLDLSRNQFSGAVPRKLGSLSELMQLKLSENKLSGEIPDELSSCKKLVSLDLSHNQLSGQIPASFSEMPVLSQLD 553

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62078839  154 LAGNRLALLEPSILGPLPLLRVLSLQDNSLSAleagllnSLP------ALDVLRLHGNPWACS----CALRPlCTWLRKH 223
Cdd:PLN00113 554 LSQNQLSGEIPKNLGNVESLVQVNISHNHLHG-------SLPstgaflAINASAVAGNIDLCGgdttSGLPP-CKRVRKT 625


                 .
gi 62078839  224 P 224
Cdd:PLN00113 626 P 626
LRR_8 pfam13855
Leucine rich repeat;
147-206 5.10e-06

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 43.28  E-value: 5.10e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 62078839   147 RALSFLSLAGNRLALLEPSILGPLPLLRVLSLQDNSLSALEAGLLNSLPALDVLRLHGNP 206
Cdd:pfam13855   1 PNLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNR 60
PLN03150 PLN03150
hypothetical protein; Provisional
 125-204 5.48e-06

hypothetical protein; Provisional


Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 47.89  E-value: 5.48e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62078839  125 LQRLDLSSNQLETLSPGTFTPLRALSFLSLAGNRLALLEPSILGPLPLLRVLSLQDNSLSALEAGLLNSLPaldvlrLHG 204
Cdd:PLN03150 444 LQSINLSGNSIRGNIPPSLGSITSLEVLDLSYNSFNGSIPESLGQLTSLRILNLNGNSLSGRVPAALGGRL------LHR 517
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 125-206 1.30e-05

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 45.55  E-value: 1.30e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62078839 125 LQRLDLSSNQLETLSPgtftplralsflslagnrlallepsiLGPLPLLRVLSLQDNSLSALE--AGLLNSLPALDVLRL 202
Cdd:cd21340 122 LRVLNISGNNIDSLEP--------------------------LAPLRNLEQLDASNNQISDLEelLDLLSSWPSLRELDL 175


                ....
gi 62078839 203 HGNP 206
Cdd:cd21340 176 TGNP 179
PCC TIGR00864
polycystin cation channel protein; The Polycystin Cation Channel (PCC) Family (TC 1.A.5) ...
 178-295 5.16e-05

polycystin cation channel protein; The Polycystin Cation Channel (PCC) Family (TC 1.A.5) Polycystin is a huge protein of 4303aas. Its repeated leucine-rich (LRR) segment is found in many proteins. It contains 16 polycystic kidney disease (PKD) domains, one LDL-receptor class A domain, one C-type lectin family domain, and 16-18 putative TMSs in positions between residues 2200 and 4100. Polycystin-L has been shown to be a cation (Na+, K+ and Ca2+) channel that is activated by Ca2+. Two members of the PCC family (polycystin 1 and 2) are mutated in autosomal dominant polycystic kidney disease, and polycystin-L is deleted in mice with renal and retinal defects. Note: this model is restricted to the amino half.


Pssm-ID: 188093 [Multi-domain]  Cd Length: 2740  Bit Score: 45.07  E-value: 5.16e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62078839    178 LQDNSLSALEAGLLNSLPALDVLRLHGNPWACSCALRPLCTWLRKHPRPTSETETLLCVSP------KLQTLNLLTDFPD 251
Cdd:TIGR00864    2 ISNNKISTIEEGICANLCNLSEIDLSGNPFECDCGLARLPRWAEEKGVKVRQPEAALCAGPgalagqPLLGIPLLDSGCD 81

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|..
gi 62078839    252 NAFKQC-----TQSLAARDLAVVYALGPASFL---ASLAICLALGSVLTACG 295
Cdd:TIGR00864   82 EEYVAClkdnsSGGGAARSELVIFSAAHEGLFqpeACNAFCFSAGHGLAALG 133
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 85-199 6.02e-05

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 44.84  E-value: 6.02e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62078839   85 NRVSTLPPGAFADAGALLYLVLRENRLRSVHARAFWGLGVLQRLDLSSNQLETLSPGTFTPLRALSFLSLAGNRLALLEP 164
Cdd:PLN00113 246 NNLTGPIPSSLGNLKNLQYLFLYQNKLSGPIPPSIFSLQKLISLDLSDNSLSGEIPELVIQLQNLEILHLFSNNFTGKIP 325

                         90       100       110
                 ....*....|....*....|....*....|....*...
gi 62078839  165 SILGPLPLLRVLSLQDNSLSA---LEAGLLNSLPALDV 199
Cdd:PLN00113 326 VALTSLPRLQVLQLWSNKFSGeipKNLGKHNNLTVLDL 363
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 118-205 3.15e-04

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 42.53  E-value: 3.15e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62078839  118 AFWGLGVLQRLDLSSNQLETLSPGT-FTPLRALSFLSLAGNRLALLEPSilGPLPLLRVLSLQDNSLSA---LEAGLLNS 193
Cdd:PLN00113  88 AIFRLPYIQTINLSNNQLSGPIPDDiFTTSSSLRYLNLSNNNFTGSIPR--GSIPNLETLDLSNNMLSGeipNDIGSFSS 165

                         90
                 ....*....|..
gi 62078839  194 LPALDvlrLHGN 205
Cdd:PLN00113 166 LKVLD---LGGN 174
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 77-183 4.88e-04

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 42.14  E-value: 4.88e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62078839   77 VRSLLLDRNRVS-TLPPGAFADAGALLYLVLRENRLRSVHARAFwgLGVLQRLDLSSNQLETLSPGTFTPLRALSFLSLA 155
Cdd:PLN00113  95 IQTINLSNNQLSgPIPDDIFTTSSSLRYLNLSNNNFTGSIPRGS--IPNLETLDLSNNMLSGEIPNDIGSFSSLKVLDLG 172

                         90       100
                 ....*....|....*....|....*...
gi 62078839  156 GNRLALLEPSILGPLPLLRVLSLQDNSL 183
Cdd:PLN00113 173 GNVLVGKIPNSLTNLTSLEFLTLASNQL 200
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
66-205 5.56e-04

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 41.46  E-value: 5.56e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62078839  66 LPAVPAGLSwQVRSLLLDRNRVSTLPpgAFADAGALLYLVLRENRLRSVHARAfwGLGVLQRLDLSSNQLETLSPGTFTP 145
Cdd:COG4886 220 LPEPLANLT-NLETLDLSNNQLTDLP--ELGNLTNLEELDLSNNQLTDLPPLA--NLTNLKTLDLSNNQLTDLKLKELEL 294

                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|
gi 62078839 146 LRALSFLSLAGNRLALLEPSILGPLPLLRVLSLQDNSLSALEAGLLNSLPALDVLRLHGN 205
Cdd:COG4886 295 LLGLNSLLLLLLLLNLLELLILLLLLTTLLLLLLLLKGLLVTLTTLALSLSLLALLTLLL 354
LRRCT smart00082
Leucine rich repeat C-terminal domain;
205-258 8.59e-04

Leucine rich repeat C-terminal domain;


Pssm-ID: 214507 [Multi-domain]  Cd Length: 51  Bit Score: 36.64  E-value: 8.59e-04
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....
gi 62078839    205 NPWACSCALRPLCTWLRKHPRpTSETETLLCVSPKLQTLNLLTDfpDNAFKQCT 258
Cdd:smart00082   1 NPFICDCELRWLLRWLQANEH-LQDPVDLRCASPSSLRGPLLEL--LHSEFKCP 51
PLN03150 PLN03150
hypothetical protein; Provisional
 75-174 9.35e-04

hypothetical protein; Provisional


Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 40.95  E-value: 9.35e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62078839   75 WQVRSLLLDRNRVSTLPPGAFADAGALLYLVLRENRLRSVHARAFWGLGVLQRLDLSSNQLETLSPGTFTPLRALSFLSL 154
Cdd:PLN03150 418 WFIDGLGLDNQGLRGFIPNDISKLRHLQSINLSGNSIRGNIPPSLGSITSLEVLDLSYNSFNGSIPESLGQLTSLRILNL 497

                         90       100
                 ....*....|....*....|
gi 62078839  155 AGNRLALLEPSILGPLPLLR 174
Cdd:PLN03150 498 NGNSLSGRVPAALGGRLLHR 517
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 76-184 1.66e-03

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 40.22  E-value: 1.66e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62078839   76 QVRSLLLDRNRVSTLPPGAFAdAGALLYLVLRENRLRSVHARAFWGLGVLQRLDLSSNQLETLSPGTFTPLRALSFLSLA 155
Cdd:PLN00113 453 SLQMLSLARNKFFGGLPDSFG-SKRLENLDLSRNQFSGAVPRKLGSLSELMQLKLSENKLSGEIPDELSSCKKLVSLDLS 531

                         90       100
                 ....*....|....*....|....*....
gi 62078839  156 GNRLALLEPSILGPLPLLRVLSLQDNSLS 184
Cdd:PLN00113 532 HNQLSGQIPASFSEMPVLSQLDLSQNQLS 560
PLN03150 PLN03150
hypothetical protein; Provisional
 124-205 1.82e-03

hypothetical protein; Provisional


Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 40.18  E-value: 1.82e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62078839  124 VLQRLDLSSNQLETLSPGTFTPLRALSFLSLAGNRLALLEPSILGPLPLLRVLSLQDNSLSALEAGLLNSLPALDVLRLH 203
Cdd:PLN03150 419 FIDGLGLDNQGLRGFIPNDISKLRHLQSINLSGNSIRGNIPPSLGSITSLEVLDLSYNSFNGSIPESLGQLTSLRILNLN 498


                 ..
gi 62078839  204 GN 205
Cdd:PLN03150 499 GN 500
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 121-205 3.16e-03

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 39.45  E-value: 3.16e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62078839  121 GLGVLQRLDLSSNQLETLSPGTFTPLRALSFLSLAGNRLA-LLEPSILGpLPLLRVLSLQDNSLSALEAGLLNSLPALDV 199
Cdd:PLN00113 234 GLTSLNHLDLVYNNLTGPIPSSLGNLKNLQYLFLYQNKLSgPIPPSIFS-LQKLISLDLSDNSLSGEIPELVIQLQNLEI 312


                 ....*.
gi 62078839  200 LRLHGN 205
Cdd:PLN00113 313 LHLFSN 318
LRR_4 pfam12799
Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a ...
 171-206 6.47e-03

Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a number of proteins with diverse functions and cellular locations. These repeats are usually involved in protein-protein interactions. Each Leucine Rich Repeat is composed of a beta-alpha unit. These units form elongated non-globular structures. Leucine Rich Repeats are often flanked by cysteine rich domains.


Pssm-ID: 463713 [Multi-domain]  Cd Length: 44  Bit Score: 34.14  E-value: 6.47e-03
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 62078839   171 PLLRVLSLQDNSLSALEagLLNSLPALDVLRLHGNP 206
Cdd:pfam12799   1 PNLEVLDLSNNQITDIP--PLAKLPNLETLDLSGNN 34
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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