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Conserved domains on  [gi|157820121|ref|NP_001103100|]
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solute carrier family 12 member 6 [Rattus norvegicus]

Protein Classification

solute carrier family 12 protein( domain architecture ID 11489985)

solute carrier family 12 protein similar to Arabidopsis thaliana cation-chloride cotransporter 1, which mediates both potassium-chloride and sodium-chloride cotransports and is involved in plant development and Cl(-) homeostasis

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
2a30 TIGR00930
K-Cl cotransporter; [Transport and binding proteins, Other]
109-1150 0e+00

K-Cl cotransporter; [Transport and binding proteins, Other]


:

Pssm-ID: 273347 [Multi-domain]  Cd Length: 953  Bit Score: 1353.23  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157820121   109 HKKARNAYLNNSNYEEGDEYFDKNLALFEEEMDTRPKVSSLLNRMANYTNLTQGAKEHEEAENITEGKKKP-TKSPQMGT 187
Cdd:TIGR00930    1 NTVDAVPRIEHYRNSEGQGGPKRNRPSLEELHDLLDKVVSLLGPLADYTNNGQGMKEHEEAEDAEGTKEKPpAGAVKFGW 80
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157820121   188 FMGVYLPCLQNIFGVILFLRLTWVVGTAGVLQAFAIVLICCCCTMLTAISMSAIATNGVVPAGGSYFMISRALGPEFGGA 267
Cdd:TIGR00930   81 VMGVLVPCLLNIWGVILFLRLSWIVGQAGIGLSLLIILLCCCVTTITGLSMSAIATNGVVKGGGAYYLISRSLGPEFGGS 160
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157820121   268 VGLCFYLGTTFAAAMYILGAIEIFLvyivpraAIFRSDdALKESAAMLNNMRVYGTAFLVLMVLVVFIGVRYVNKFASLF 347
Cdd:TIGR00930  161 IGLIFAFANAVAVAMYVVGFAETVL-------DLLREN-GSKIMVDPINDIRIYGTVTVVVLLGISFAGMEWENKAQVLF 232
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157820121   348 LACVIVSILAIYAGAIKSSFAPPHFPVCMLGNRTlssrhldicsktkevnnmtipsklwgffcnssqffnatcdeyFVHN 427
Cdd:TIGR00930  233 LVIVLLSILNIFVGTIIPAFDKPAKGFFGLGNEI------------------------------------------FSEN 270
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157820121   428 NvtsIQGIPGLASGiitenlwsnylpkgeiiekpsakssdvlgnlnheyvladittsFTLLVGIFFPSVTGIMAGSNRSG 507
Cdd:TIGR00930  271 F---IPGIPGPEGG-------------------------------------------FFSLFGIFFPSVTGILAGANISG 304
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157820121   508 DLKDAQKSIPIGTILAILTTSFVYLSNVVLFGACIEGVVLRDKFGDAVK---------------------GNLVVGTLSW 566
Cdd:TIGR00930  305 DLKDPQKAIPKGTLLAILTTTVVYLGSVVLFGACVVRDATGDKNDTLVTnctsaacfsecahntcsyglmNNLQVMSLVS 384
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157820121   567 PSPWVIVIGSFFSTCGAGLQSLTGAPRLLQAIAKDNIIPFLRVFGHSKA-NGEPTWALLLTAAIAELGILIASLDLVAPI 645
Cdd:TIGR00930  385 PFPPLITAGIFSATLSSALASLVSAPRLFQALCKDNIYPFLQFFGKGYGkNGEPLRAYLLTAFIAEGFILIAELNTIAPI 464
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157820121   646 LSMFFLMCYLFVNLACALQTLLRTPHWRPRFRYYHWALSFMGMSICLALMFISSWYYAIVAMVIAGMIYKYIEYQGAEKE 725
Cdd:TIGR00930  465 ISNFFLASYALINFSCFHASLLRSPGWRPRFKYYHWWLSLLGASLCCAIMFLISWWAALVAMVIALFLYKYVTYKKPDVN 544
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157820121   726 WGDGIRGLSLSAARFALLRLEEGPPHTKNWRPQLLVLLKLDedlhVKHPRLLTFASQLKAGKGLTIVGSVIVGNFLENYG 805
Cdd:TIGR00930  545 WGSSTQALSYSLALYSLLRLEEVEDHVKNWRPQCLVLTGPP----VCRPALLDFASQFTKGKGLMICGSVIQGPRLECVK 620
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157820121   806 DALAAEQTIKHLMEAEKVKGFCQLVVAAKLKEGISHLIQSCGLGGMKHNTVVMGWPNGWRQSEdARAWKTFIGTVRVTTA 885
Cdd:TIGR00930  621 EAQAAEAKIQTWLEKNKVKAFYAVVVADDLREGVRHLIQASGLGRMKPNTLVMGYKKDWRQAE-PRAWETYIGIIHDAFD 699
                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157820121   886 AHLALLVAKNVSFFPSNV--------------------------------------EQFSEGNIDVWWIVHDGGMLMLLP 927
Cdd:TIGR00930  700 AHLAVVVVRNSEGLPISVlqvqeelendcsedsielndgkistqpdmhleastqfqKKQGKGTIDVWWLVDDGGLTLLLP 779
                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157820121   928 FLLKQHKVWRKCSIRIFTVAQLEDNSIQMKKDLATFLYHLRIEAEVEVVEMhdsDISAytYERTLMMEQRSQMLRHMRLS 1007
Cdd:TIGR00930  780 YLLTTKKVWKKCKIRIFVGAQKDDRSEQEKKDMATLLYKFRIDAEVIVVLM---DINA--KPQTESMEAFEEMIRPFRLH 854
                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157820121  1008 KTERDREAqlvKDRnsmlrltsigsdedeetetyqekvHMTWTKDKYMASrgqkvksmegfQDLlnmrpdQSNVRRMHTA 1087
Cdd:TIGR00930  855 KTEKDREA---KDP------------------------KMTWTKPWKITD-----------AEL------QSNVRKSYRQ 890
                         1050      1060      1070      1080      1090      1100
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 157820121  1088 VKLNEVIVNKSHEAKLVLLNMPGPPRNPEGDENYMEFLEVLTEGLERVLLVRGGGSEVITIYS 1150
Cdd:TIGR00930  891 VRLNELLLEYSRDAALVVLSLPVPRKGSIPDELYMAWLEVLSEDLPPVLLVRGNHRNVLTFYS 953
 
Name Accession Description Interval E-value
2a30 TIGR00930
K-Cl cotransporter; [Transport and binding proteins, Other]
109-1150 0e+00

K-Cl cotransporter; [Transport and binding proteins, Other]


Pssm-ID: 273347 [Multi-domain]  Cd Length: 953  Bit Score: 1353.23  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157820121   109 HKKARNAYLNNSNYEEGDEYFDKNLALFEEEMDTRPKVSSLLNRMANYTNLTQGAKEHEEAENITEGKKKP-TKSPQMGT 187
Cdd:TIGR00930    1 NTVDAVPRIEHYRNSEGQGGPKRNRPSLEELHDLLDKVVSLLGPLADYTNNGQGMKEHEEAEDAEGTKEKPpAGAVKFGW 80
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157820121   188 FMGVYLPCLQNIFGVILFLRLTWVVGTAGVLQAFAIVLICCCCTMLTAISMSAIATNGVVPAGGSYFMISRALGPEFGGA 267
Cdd:TIGR00930   81 VMGVLVPCLLNIWGVILFLRLSWIVGQAGIGLSLLIILLCCCVTTITGLSMSAIATNGVVKGGGAYYLISRSLGPEFGGS 160
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157820121   268 VGLCFYLGTTFAAAMYILGAIEIFLvyivpraAIFRSDdALKESAAMLNNMRVYGTAFLVLMVLVVFIGVRYVNKFASLF 347
Cdd:TIGR00930  161 IGLIFAFANAVAVAMYVVGFAETVL-------DLLREN-GSKIMVDPINDIRIYGTVTVVVLLGISFAGMEWENKAQVLF 232
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157820121   348 LACVIVSILAIYAGAIKSSFAPPHFPVCMLGNRTlssrhldicsktkevnnmtipsklwgffcnssqffnatcdeyFVHN 427
Cdd:TIGR00930  233 LVIVLLSILNIFVGTIIPAFDKPAKGFFGLGNEI------------------------------------------FSEN 270
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157820121   428 NvtsIQGIPGLASGiitenlwsnylpkgeiiekpsakssdvlgnlnheyvladittsFTLLVGIFFPSVTGIMAGSNRSG 507
Cdd:TIGR00930  271 F---IPGIPGPEGG-------------------------------------------FFSLFGIFFPSVTGILAGANISG 304
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157820121   508 DLKDAQKSIPIGTILAILTTSFVYLSNVVLFGACIEGVVLRDKFGDAVK---------------------GNLVVGTLSW 566
Cdd:TIGR00930  305 DLKDPQKAIPKGTLLAILTTTVVYLGSVVLFGACVVRDATGDKNDTLVTnctsaacfsecahntcsyglmNNLQVMSLVS 384
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157820121   567 PSPWVIVIGSFFSTCGAGLQSLTGAPRLLQAIAKDNIIPFLRVFGHSKA-NGEPTWALLLTAAIAELGILIASLDLVAPI 645
Cdd:TIGR00930  385 PFPPLITAGIFSATLSSALASLVSAPRLFQALCKDNIYPFLQFFGKGYGkNGEPLRAYLLTAFIAEGFILIAELNTIAPI 464
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157820121   646 LSMFFLMCYLFVNLACALQTLLRTPHWRPRFRYYHWALSFMGMSICLALMFISSWYYAIVAMVIAGMIYKYIEYQGAEKE 725
Cdd:TIGR00930  465 ISNFFLASYALINFSCFHASLLRSPGWRPRFKYYHWWLSLLGASLCCAIMFLISWWAALVAMVIALFLYKYVTYKKPDVN 544
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157820121   726 WGDGIRGLSLSAARFALLRLEEGPPHTKNWRPQLLVLLKLDedlhVKHPRLLTFASQLKAGKGLTIVGSVIVGNFLENYG 805
Cdd:TIGR00930  545 WGSSTQALSYSLALYSLLRLEEVEDHVKNWRPQCLVLTGPP----VCRPALLDFASQFTKGKGLMICGSVIQGPRLECVK 620
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157820121   806 DALAAEQTIKHLMEAEKVKGFCQLVVAAKLKEGISHLIQSCGLGGMKHNTVVMGWPNGWRQSEdARAWKTFIGTVRVTTA 885
Cdd:TIGR00930  621 EAQAAEAKIQTWLEKNKVKAFYAVVVADDLREGVRHLIQASGLGRMKPNTLVMGYKKDWRQAE-PRAWETYIGIIHDAFD 699
                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157820121   886 AHLALLVAKNVSFFPSNV--------------------------------------EQFSEGNIDVWWIVHDGGMLMLLP 927
Cdd:TIGR00930  700 AHLAVVVVRNSEGLPISVlqvqeelendcsedsielndgkistqpdmhleastqfqKKQGKGTIDVWWLVDDGGLTLLLP 779
                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157820121   928 FLLKQHKVWRKCSIRIFTVAQLEDNSIQMKKDLATFLYHLRIEAEVEVVEMhdsDISAytYERTLMMEQRSQMLRHMRLS 1007
Cdd:TIGR00930  780 YLLTTKKVWKKCKIRIFVGAQKDDRSEQEKKDMATLLYKFRIDAEVIVVLM---DINA--KPQTESMEAFEEMIRPFRLH 854
                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157820121  1008 KTERDREAqlvKDRnsmlrltsigsdedeetetyqekvHMTWTKDKYMASrgqkvksmegfQDLlnmrpdQSNVRRMHTA 1087
Cdd:TIGR00930  855 KTEKDREA---KDP------------------------KMTWTKPWKITD-----------AEL------QSNVRKSYRQ 890
                         1050      1060      1070      1080      1090      1100
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 157820121  1088 VKLNEVIVNKSHEAKLVLLNMPGPPRNPEGDENYMEFLEVLTEGLERVLLVRGGGSEVITIYS 1150
Cdd:TIGR00930  891 VRLNELLLEYSRDAALVVLSLPVPRKGSIPDELYMAWLEVLSEDLPPVLLVRGNHRNVLTFYS 953
AA_permease pfam00324
Amino acid permease;
190-760 1.76e-48

Amino acid permease;


Pssm-ID: 366028 [Multi-domain]  Cd Length: 467  Bit Score: 180.21  E-value: 1.76e-48
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157820121   190 GVYLPCLQNIFGVILFLRLTWVVGTAGVLQAFAIVLICCCCTMLTAISMSAIATNGVVpAGGSYFMISRALGPEFGGAVG 269
Cdd:pfam00324    1 HVQMIALGGVIGTGLFVGSGSVLGQAGPAGALLGYLISGVVIFLVMLSLGEISTNGPV-SGGFYTYASRFLGPSLGFATG 79
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157820121   270 L--CFYLGTTFAAAmyiLGAIEIFLVYIVPRAAIfrsddalkesaamlNNMRVYGTAFLVLMVLVVFIGVRYVNKFASLF 347
Cdd:pfam00324   80 WnyWLSWITVLALE---LTAASILIQFWELVPDI--------------PYLWVWGAVFLVLLTIINLVGVKWYGEAEFWF 142
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157820121   348 LACVIVSILAIYAGAI--KSSFAPPHFPVcmlgnrtlssrhldicsktkevnnmtipsklwgffcnSSQFFNATCDEYFV 425
Cdd:pfam00324  143 ALIKIIAIIGFIIVGIilLSGGNPNDGAI-------------------------------------FRYLGDNGGKNNFP 185
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157820121   426 HNNVTSIqgipglASGIItenlwsnylpkgeiiekpsakssdvlgnlnheyvladittsftllvgIFFPSVTGIMAGSNR 505
Cdd:pfam00324  186 PGFGKGF------ISVFV-----------------------------------------------IAFFAFTGIELVGIA 212
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157820121   506 SGDLKDAQKSIPIGTILAILTTSFVYLSNVVLFGACIEG--VVLRDKFGDAVKGNLVVGTLSWPS--PWVIVIGSFFSTC 581
Cdd:pfam00324  213 AGEVKNPEKSIPKAILQVIWRITIFYILSLLAIGLLVPWndPGLLNDSASAASPFVIFFKFLGISglAPLINAVILTAAL 292
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157820121   582 GAGLQSLTGAPRLLQAIAKDNIIPFlrVFGHSKANGEPTWALLLTAAIAELGILIASldLVAPILSMFFLMCYLFVNLAC 661
Cdd:pfam00324  293 SAANSSLYSGSRMLYSLARDGLAPK--FLKKVDKRGVPLRAILVSMVISLLALLLAS--LNPAIVFNFLLAISGLSGLIV 368
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157820121   662 ALQTLLRTPHWRPRFRYYHWALSFMGMSICLALMFISSWYYAIVAMVIAGMIYKYIEYQGAEKEWGDGIRGLSLSAARFA 741
Cdd:pfam00324  369 WGLISLSHLRFRKAFKYQGRSIDELPFKAPLGPLGVILGLAAIIIILIIQFLYAFLPVPGGPKNWGAGSFAAAYLIVLLF 448
                          570
                   ....*....|....*....
gi 157820121   742 LLRLEEGPPHTKNWRPQLL 760
Cdd:pfam00324  449 LIILIGVKLHVKNWKPQLL 467
PotE COG0531
Serine transporter YbeC, amino acid:H+ symporter family [Amino acid transport and metabolism];
198-720 6.58e-36

Serine transporter YbeC, amino acid:H+ symporter family [Amino acid transport and metabolism];


Pssm-ID: 440297 [Multi-domain]  Cd Length: 438  Bit Score: 142.34  E-value: 6.58e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157820121  198 NIFGVILFLRLTWVVGTAG--VLQAFAIVLICCcctMLTAISMSAIATNgvVP-AGGSYFMISRALGPEFGGAVGLCFYL 274
Cdd:COG0531    25 AIIGAGIFVLPGLAAGLAGpaAILAWLIAGLLA---LLVALSYAELASA--FPrAGGAYTYARRALGPLLGFLAGWALLL 99
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157820121  275 GTTFAAAMYILGAIEiFLVYIVPRAAIFrsddalkesaamlnnmrVYGTAFLVLMVLVVFIGVRYVNKFASLFLACVIVS 354
Cdd:COG0531   100 SYVLAVAAVAVAFGG-YLSSLFPAGGSV-----------------LIALVLILLLTLLNLRGVKESAKVNNILTVLKLLV 161
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157820121  355 ILAIYAGAIkSSFAPPHFpvcmlgnrtlssrhldicsktkevnnmtipsklwgffcnsSQFFNATcdeyfvhnnvtsiQG 434
Cdd:COG0531   162 LLLFIVVGL-FAFDPANF----------------------------------------TPFLPAG-------------GG 187
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157820121  435 IPGLASGIitenlwsnylpkgeiiekpsakssdvlgnlnheyvladittsftllvGIFFPSVTGIMAGSNRSGDLKDAQK 514
Cdd:COG0531   188 LSGVLAAL-----------------------------------------------ALAFFAFTGFEAIANLAEEAKNPKR 220
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157820121  515 SIPIGTILAILTTSFVYlsnvVLFGACIEGVVLRDKFGDAVKGNLVVGTLSWPSP--WVIVIGSFFSTCGAGLQSLTGAP 592
Cdd:COG0531   221 NIPRAIILSLLIVGVLY----ILVSLALTGVVPYDELAASGAPLADAAEAVFGPWgaILIALGALLSLLGALNASILGAS 296
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157820121  593 RLLQAIAKDNIIPflRVFGH-SKANGEPTWALLLTAAIAELGILI--ASLDLVAPILSMFFLMCYLFVNLAcALQTLLRT 669
Cdd:COG0531   297 RLLYAMARDGLLP--KVFAKvHPRFGTPVNAILLTGVIALLLLLLgaASFTALASLASVGVLLAYLLVALA-VIVLRRRR 373
                         490       500       510       520       530
                  ....*....|....*....|....*....|....*....|....*....|....
gi 157820121  670 PHWRPRFRYYHWALSFMGMSICLALMFIS---SWYYAIVAMVIAGMIYKYIEYQ 720
Cdd:COG0531   374 PDLPRPFRVPLPLIPILGILLCLFLLYLLgpgALLIGLVLLAIGLLLYLLYRRR 427
 
Name Accession Description Interval E-value
2a30 TIGR00930
K-Cl cotransporter; [Transport and binding proteins, Other]
109-1150 0e+00

K-Cl cotransporter; [Transport and binding proteins, Other]


Pssm-ID: 273347 [Multi-domain]  Cd Length: 953  Bit Score: 1353.23  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157820121   109 HKKARNAYLNNSNYEEGDEYFDKNLALFEEEMDTRPKVSSLLNRMANYTNLTQGAKEHEEAENITEGKKKP-TKSPQMGT 187
Cdd:TIGR00930    1 NTVDAVPRIEHYRNSEGQGGPKRNRPSLEELHDLLDKVVSLLGPLADYTNNGQGMKEHEEAEDAEGTKEKPpAGAVKFGW 80
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157820121   188 FMGVYLPCLQNIFGVILFLRLTWVVGTAGVLQAFAIVLICCCCTMLTAISMSAIATNGVVPAGGSYFMISRALGPEFGGA 267
Cdd:TIGR00930   81 VMGVLVPCLLNIWGVILFLRLSWIVGQAGIGLSLLIILLCCCVTTITGLSMSAIATNGVVKGGGAYYLISRSLGPEFGGS 160
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157820121   268 VGLCFYLGTTFAAAMYILGAIEIFLvyivpraAIFRSDdALKESAAMLNNMRVYGTAFLVLMVLVVFIGVRYVNKFASLF 347
Cdd:TIGR00930  161 IGLIFAFANAVAVAMYVVGFAETVL-------DLLREN-GSKIMVDPINDIRIYGTVTVVVLLGISFAGMEWENKAQVLF 232
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157820121   348 LACVIVSILAIYAGAIKSSFAPPHFPVCMLGNRTlssrhldicsktkevnnmtipsklwgffcnssqffnatcdeyFVHN 427
Cdd:TIGR00930  233 LVIVLLSILNIFVGTIIPAFDKPAKGFFGLGNEI------------------------------------------FSEN 270
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157820121   428 NvtsIQGIPGLASGiitenlwsnylpkgeiiekpsakssdvlgnlnheyvladittsFTLLVGIFFPSVTGIMAGSNRSG 507
Cdd:TIGR00930  271 F---IPGIPGPEGG-------------------------------------------FFSLFGIFFPSVTGILAGANISG 304
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157820121   508 DLKDAQKSIPIGTILAILTTSFVYLSNVVLFGACIEGVVLRDKFGDAVK---------------------GNLVVGTLSW 566
Cdd:TIGR00930  305 DLKDPQKAIPKGTLLAILTTTVVYLGSVVLFGACVVRDATGDKNDTLVTnctsaacfsecahntcsyglmNNLQVMSLVS 384
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157820121   567 PSPWVIVIGSFFSTCGAGLQSLTGAPRLLQAIAKDNIIPFLRVFGHSKA-NGEPTWALLLTAAIAELGILIASLDLVAPI 645
Cdd:TIGR00930  385 PFPPLITAGIFSATLSSALASLVSAPRLFQALCKDNIYPFLQFFGKGYGkNGEPLRAYLLTAFIAEGFILIAELNTIAPI 464
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157820121   646 LSMFFLMCYLFVNLACALQTLLRTPHWRPRFRYYHWALSFMGMSICLALMFISSWYYAIVAMVIAGMIYKYIEYQGAEKE 725
Cdd:TIGR00930  465 ISNFFLASYALINFSCFHASLLRSPGWRPRFKYYHWWLSLLGASLCCAIMFLISWWAALVAMVIALFLYKYVTYKKPDVN 544
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157820121   726 WGDGIRGLSLSAARFALLRLEEGPPHTKNWRPQLLVLLKLDedlhVKHPRLLTFASQLKAGKGLTIVGSVIVGNFLENYG 805
Cdd:TIGR00930  545 WGSSTQALSYSLALYSLLRLEEVEDHVKNWRPQCLVLTGPP----VCRPALLDFASQFTKGKGLMICGSVIQGPRLECVK 620
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157820121   806 DALAAEQTIKHLMEAEKVKGFCQLVVAAKLKEGISHLIQSCGLGGMKHNTVVMGWPNGWRQSEdARAWKTFIGTVRVTTA 885
Cdd:TIGR00930  621 EAQAAEAKIQTWLEKNKVKAFYAVVVADDLREGVRHLIQASGLGRMKPNTLVMGYKKDWRQAE-PRAWETYIGIIHDAFD 699
                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157820121   886 AHLALLVAKNVSFFPSNV--------------------------------------EQFSEGNIDVWWIVHDGGMLMLLP 927
Cdd:TIGR00930  700 AHLAVVVVRNSEGLPISVlqvqeelendcsedsielndgkistqpdmhleastqfqKKQGKGTIDVWWLVDDGGLTLLLP 779
                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157820121   928 FLLKQHKVWRKCSIRIFTVAQLEDNSIQMKKDLATFLYHLRIEAEVEVVEMhdsDISAytYERTLMMEQRSQMLRHMRLS 1007
Cdd:TIGR00930  780 YLLTTKKVWKKCKIRIFVGAQKDDRSEQEKKDMATLLYKFRIDAEVIVVLM---DINA--KPQTESMEAFEEMIRPFRLH 854
                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157820121  1008 KTERDREAqlvKDRnsmlrltsigsdedeetetyqekvHMTWTKDKYMASrgqkvksmegfQDLlnmrpdQSNVRRMHTA 1087
Cdd:TIGR00930  855 KTEKDREA---KDP------------------------KMTWTKPWKITD-----------AEL------QSNVRKSYRQ 890
                         1050      1060      1070      1080      1090      1100
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 157820121  1088 VKLNEVIVNKSHEAKLVLLNMPGPPRNPEGDENYMEFLEVLTEGLERVLLVRGGGSEVITIYS 1150
Cdd:TIGR00930  891 VRLNELLLEYSRDAALVVLSLPVPRKGSIPDELYMAWLEVLSEDLPPVLLVRGNHRNVLTFYS 953
AA_permease pfam00324
Amino acid permease;
190-760 1.76e-48

Amino acid permease;


Pssm-ID: 366028 [Multi-domain]  Cd Length: 467  Bit Score: 180.21  E-value: 1.76e-48
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157820121   190 GVYLPCLQNIFGVILFLRLTWVVGTAGVLQAFAIVLICCCCTMLTAISMSAIATNGVVpAGGSYFMISRALGPEFGGAVG 269
Cdd:pfam00324    1 HVQMIALGGVIGTGLFVGSGSVLGQAGPAGALLGYLISGVVIFLVMLSLGEISTNGPV-SGGFYTYASRFLGPSLGFATG 79
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157820121   270 L--CFYLGTTFAAAmyiLGAIEIFLVYIVPRAAIfrsddalkesaamlNNMRVYGTAFLVLMVLVVFIGVRYVNKFASLF 347
Cdd:pfam00324   80 WnyWLSWITVLALE---LTAASILIQFWELVPDI--------------PYLWVWGAVFLVLLTIINLVGVKWYGEAEFWF 142
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157820121   348 LACVIVSILAIYAGAI--KSSFAPPHFPVcmlgnrtlssrhldicsktkevnnmtipsklwgffcnSSQFFNATCDEYFV 425
Cdd:pfam00324  143 ALIKIIAIIGFIIVGIilLSGGNPNDGAI-------------------------------------FRYLGDNGGKNNFP 185
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157820121   426 HNNVTSIqgipglASGIItenlwsnylpkgeiiekpsakssdvlgnlnheyvladittsftllvgIFFPSVTGIMAGSNR 505
Cdd:pfam00324  186 PGFGKGF------ISVFV-----------------------------------------------IAFFAFTGIELVGIA 212
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157820121   506 SGDLKDAQKSIPIGTILAILTTSFVYLSNVVLFGACIEG--VVLRDKFGDAVKGNLVVGTLSWPS--PWVIVIGSFFSTC 581
Cdd:pfam00324  213 AGEVKNPEKSIPKAILQVIWRITIFYILSLLAIGLLVPWndPGLLNDSASAASPFVIFFKFLGISglAPLINAVILTAAL 292
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157820121   582 GAGLQSLTGAPRLLQAIAKDNIIPFlrVFGHSKANGEPTWALLLTAAIAELGILIASldLVAPILSMFFLMCYLFVNLAC 661
Cdd:pfam00324  293 SAANSSLYSGSRMLYSLARDGLAPK--FLKKVDKRGVPLRAILVSMVISLLALLLAS--LNPAIVFNFLLAISGLSGLIV 368
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157820121   662 ALQTLLRTPHWRPRFRYYHWALSFMGMSICLALMFISSWYYAIVAMVIAGMIYKYIEYQGAEKEWGDGIRGLSLSAARFA 741
Cdd:pfam00324  369 WGLISLSHLRFRKAFKYQGRSIDELPFKAPLGPLGVILGLAAIIIILIIQFLYAFLPVPGGPKNWGAGSFAAAYLIVLLF 448
                          570
                   ....*....|....*....
gi 157820121   742 LLRLEEGPPHTKNWRPQLL 760
Cdd:pfam00324  449 LIILIGVKLHVKNWKPQLL 467
PotE COG0531
Serine transporter YbeC, amino acid:H+ symporter family [Amino acid transport and metabolism];
198-720 6.58e-36

Serine transporter YbeC, amino acid:H+ symporter family [Amino acid transport and metabolism];


Pssm-ID: 440297 [Multi-domain]  Cd Length: 438  Bit Score: 142.34  E-value: 6.58e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157820121  198 NIFGVILFLRLTWVVGTAG--VLQAFAIVLICCcctMLTAISMSAIATNgvVP-AGGSYFMISRALGPEFGGAVGLCFYL 274
Cdd:COG0531    25 AIIGAGIFVLPGLAAGLAGpaAILAWLIAGLLA---LLVALSYAELASA--FPrAGGAYTYARRALGPLLGFLAGWALLL 99
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157820121  275 GTTFAAAMYILGAIEiFLVYIVPRAAIFrsddalkesaamlnnmrVYGTAFLVLMVLVVFIGVRYVNKFASLFLACVIVS 354
Cdd:COG0531   100 SYVLAVAAVAVAFGG-YLSSLFPAGGSV-----------------LIALVLILLLTLLNLRGVKESAKVNNILTVLKLLV 161
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157820121  355 ILAIYAGAIkSSFAPPHFpvcmlgnrtlssrhldicsktkevnnmtipsklwgffcnsSQFFNATcdeyfvhnnvtsiQG 434
Cdd:COG0531   162 LLLFIVVGL-FAFDPANF----------------------------------------TPFLPAG-------------GG 187
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157820121  435 IPGLASGIitenlwsnylpkgeiiekpsakssdvlgnlnheyvladittsftllvGIFFPSVTGIMAGSNRSGDLKDAQK 514
Cdd:COG0531   188 LSGVLAAL-----------------------------------------------ALAFFAFTGFEAIANLAEEAKNPKR 220
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157820121  515 SIPIGTILAILTTSFVYlsnvVLFGACIEGVVLRDKFGDAVKGNLVVGTLSWPSP--WVIVIGSFFSTCGAGLQSLTGAP 592
Cdd:COG0531   221 NIPRAIILSLLIVGVLY----ILVSLALTGVVPYDELAASGAPLADAAEAVFGPWgaILIALGALLSLLGALNASILGAS 296
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157820121  593 RLLQAIAKDNIIPflRVFGH-SKANGEPTWALLLTAAIAELGILI--ASLDLVAPILSMFFLMCYLFVNLAcALQTLLRT 669
Cdd:COG0531   297 RLLYAMARDGLLP--KVFAKvHPRFGTPVNAILLTGVIALLLLLLgaASFTALASLASVGVLLAYLLVALA-VIVLRRRR 373
                         490       500       510       520       530
                  ....*....|....*....|....*....|....*....|....*....|....
gi 157820121  670 PHWRPRFRYYHWALSFMGMSICLALMFIS---SWYYAIVAMVIAGMIYKYIEYQ 720
Cdd:COG0531   374 PDLPRPFRVPLPLIPILGILLCLFLLYLLgpgALLIGLVLLAIGLLLYLLYRRR 427
SLC12 pfam03522
Solute carrier family 12;
774-1150 4.84e-30

Solute carrier family 12;


Pssm-ID: 460955  Cd Length: 414  Bit Score: 124.27  E-value: 4.84e-30
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157820121   774 PRLLTFASQLKAGKGLTIVGSVIVGNFLENYGDALAAEqtIKHLMEAEKVKGFCQLVVAAKLKEGISHLIQSCGLGGMKH 853
Cdd:pfam03522    2 PALVDFAHLITKNVSLMICGHVVKGRLSQKLRSELQKK--AYRWLRKRKIKAFYALVDGDNLREGAQALLQASGLGKLKP 79
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157820121   854 NTVVMGWPNGWRQSE------------DA--------------------------------------------------- 870
Cdd:pfam03522   80 NILLMGYKSDWRTCDkeeleeyfnvihDAfdlqyavailrlpegldvshllqdqdteelglgdetnssyaeqsseeqsts 159
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157820121   871 --RAWKTFIGTVRVTTAAHLALLV-------------------AKNVSFFPSNVE--------QF----SEGNIDVWWIV 917
Cdd:pfam03522  160 nsKQDDDKSKLSKKDSNLSLSPDKstknpsgkdssksdklkkkSPSIILRTASNEkeilnnitQFqkkqKKGTIDVWWLY 239
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157820121   918 HDGGMLMLLPFLLKQHKVWRKCSIRIFTVAQLEDNSIQMKKDLATFLYHLRIE-AEVEVVemhdSDISAYTYERTLMMEQ 996
Cdd:pfam03522  240 DDGGLTLLLPYILSTRSKWSDCKLRVFALGNRKDELEEEQRNMASLLSKFRIDySDLTVI----PDITKKPKKETKKFFD 315
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157820121   997 rsQMLRHMRLSKTERDREaqlvkdrnSMLRLTsigsdeDEETETYQEKVHmtwtkdkymasrgqkvksmegfqdlLNMRp 1076
Cdd:pfam03522  316 --ELIEPFRLHEDDKEEE--------SAEKIT------DSELEALKEKTN-------------------------RQLR- 353
                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 157820121  1077 dqsnvrrmhtavkLNEVIVNKSHEAKLVLLNMPGPPRNPEGDENYMEFLEVLTEGLERVLLVRGGGSEVITIYS 1150
Cdd:pfam03522  354 -------------LRELLLEHSSDANLIVMTLPMPRKGTVSAPLYMAWLETLTKDLPPFLLVRGNQTSVLTFYS 414
AA_permease_2 pfam13520
Amino acid permease;
476-717 7.24e-15

Amino acid permease;


Pssm-ID: 404414 [Multi-domain]  Cd Length: 427  Bit Score: 78.12  E-value: 7.24e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157820121   476 YVLADITTSFTLLVGIFFPSVTGIMAGSNRSGDLKdaQKSIPIGTILAILTTSFVY-LSNVVLFGAC-IEGVVLRDKFGD 553
Cdd:pfam13520  181 TFFPDGWPGVFAGFLGVLWSFTGFESAANVSEEVK--KRNVPKAIFIGVIIVGVLYiLVNIAFFGVVpDDEIALSSGLGQ 258
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157820121   554 ---AVKGNLVVGTLSWpspwVIVIGSFFSTCGAGLQSLTGAPRLLQAIAKDNIIPFLRVFGHSKANGEPTWALLLTAAIA 630
Cdd:pfam13520  259 vaaLLFQAVGGKWGAI----IVVILLALSLLGAVNTAIVGASRLLYALARDGVLPFSRFFAKVNKFGSPIRAIILTAILS 334
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157820121   631 ELGILIASLDLVAPI----LSMFFLMCYLFVNLACALqtLLRTPHWRPRFRYYHWALSFMGMsICLALMFISSWYYAIVA 706
Cdd:pfam13520  335 LILLLLFLLSPAAYNallsLSAYGYLLSYLLPIIGLL--ILRKKRPDLGRIPGRWPVAIFGI-LFSLFLIVALFFPPVGP 411
                          250
                   ....*....|.
gi 157820121   707 MVIAGMIYKYI 717
Cdd:pfam13520  412 ATGSSLNYAII 422
2A0308 TIGR00911
L-type amino acid transporter; [Transport and binding proteins, Amino acids, peptides and ...
507-706 6.31e-05

L-type amino acid transporter; [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273332 [Multi-domain]  Cd Length: 501  Bit Score: 47.05  E-value: 6.31e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157820121   507 GDLKDAQKSIPIGTILAILTTSFVY-LSNVVLFGACIEGVVLRDKFGDAVKGNLVVGTLSWPSPwvIVIGsfFSTCGAGL 585
Cdd:TIGR00911  259 EEVKNPYRTLPIAIIISMPIVTFIYvLTNIAYFTVLSPEELLASLAVAVDFGERLLGVMSWAMP--ALVG--LSCFGSVN 334
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157820121   586 QSLTGAPRLLQAIAKDNIIPFLRVFGHSKANgEPTWALLLTAAIAELGILIASLDLVAPILSMFFlmcYLFVNLACALQT 665
Cdd:TIGR00911  335 GSLFSSSRLFFVGGREGHLPSLLSMIHVKRL-TPLPSLLIVCTLTLLMLFSGDIYSLINLISFAN---WLFNALAVAGLL 410
                          170       180       190       200
                   ....*....|....*....|....*....|....*....|...
gi 157820121   666 LLR--TPHWRPRFRyyhwalsfmgMSICLALMFISSWYYAIVA 706
Cdd:TIGR00911  411 WLRykRPEMNRPIK----------VPLFFPVFFLLSCLFLIIL 443
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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