NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|300796897|ref|NP_001178483|]
View 

purine-rich element-binding protein gamma [Rattus norvegicus]

Protein Classification

Pur family transcription activator( domain architecture ID 12058637)

Pur family transcription activator such as Pur-alpha (PurA), Pur-beta (PurB), and Pur-gamma (PurG), which bind preferentially to the single strand of the purine-rich element termed PUR, which is present at origins of replication and in gene flanking regions in a variety of eukaryotes from yeasts through humans

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
PurA pfam04845
PurA ssDNA and RNA-binding protein; This family represents most of the length of the protein.
 61-325 3.10e-122

PurA ssDNA and RNA-binding protein; This family represents most of the length of the protein.


:

Pssm-ID: 282672 [Multi-domain]  Cd Length: 219  Bit Score: 351.06  E-value: 3.10e-122
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 300796897   61 IQELASKRVDIQKKRFYLDVKQSSRGRFLKIAEVWIGRgrqdniRKSKLTLSLSVAAELKDCLGDFIEHYAHLGlkghRQ 140
Cdd:pfam04845   1 EQELASKRLDIQNKRFYLDVKQNTRGRFIKIAEVGAGG------RKSRITLSMSVAAEFKDELSKFSDHYAQLG----PS 70

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 300796897  141 EHGQSKEQvsrrrqkhsapsppvsvgseehPHSVLKTDYIERDNRKYYLDLKENQRGRFLRIRQTMMRGtgmigyfgHSL 220
Cdd:pfam04845  71 NGEHLPED----------------------GSSLLKSETLVRDNRKYYLDLKENQRGRFLRIAQTPMRG--------NPR 120

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 300796897  221 GQEQTIVLPAQGMIEFRDALVQLIEDYGEGDieerrgGDDDPLELPEGTSFRVDNKRFYFDVGSNKYGIFLKVSEVRPPY 300
Cdd:pfam04845 121 GQRQQIALPAQGMIEFRDALTDLIEDYGEGD------ENDIPQELPEGTSLTVDNKRFYFDVGSNKRGVFLRISEVKPNY 194

                         250       260
                  ....*....|....*....|....*
gi 300796897  301 RNTITVPFKAWTRFGENFIKYEEEM 325
Cdd:pfam04845 195 RNSITVPEKAWTRFRDIFDKYIEKM 219
 
Name Accession Description Interval E-value
PurA pfam04845
PurA ssDNA and RNA-binding protein; This family represents most of the length of the protein.
 61-325 3.10e-122

PurA ssDNA and RNA-binding protein; This family represents most of the length of the protein.


Pssm-ID: 282672 [Multi-domain]  Cd Length: 219  Bit Score: 351.06  E-value: 3.10e-122
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 300796897   61 IQELASKRVDIQKKRFYLDVKQSSRGRFLKIAEVWIGRgrqdniRKSKLTLSLSVAAELKDCLGDFIEHYAHLGlkghRQ 140
Cdd:pfam04845   1 EQELASKRLDIQNKRFYLDVKQNTRGRFIKIAEVGAGG------RKSRITLSMSVAAEFKDELSKFSDHYAQLG----PS 70

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 300796897  141 EHGQSKEQvsrrrqkhsapsppvsvgseehPHSVLKTDYIERDNRKYYLDLKENQRGRFLRIRQTMMRGtgmigyfgHSL 220
Cdd:pfam04845  71 NGEHLPED----------------------GSSLLKSETLVRDNRKYYLDLKENQRGRFLRIAQTPMRG--------NPR 120

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 300796897  221 GQEQTIVLPAQGMIEFRDALVQLIEDYGEGDieerrgGDDDPLELPEGTSFRVDNKRFYFDVGSNKYGIFLKVSEVRPPY 300
Cdd:pfam04845 121 GQRQQIALPAQGMIEFRDALTDLIEDYGEGD------ENDIPQELPEGTSLTVDNKRFYFDVGSNKRGVFLRISEVKPNY 194

                         250       260
                  ....*....|....*....|....*
gi 300796897  301 RNTITVPFKAWTRFGENFIKYEEEM 325
Cdd:pfam04845 195 RNSITVPEKAWTRFRDIFDKYIEKM 219
PUR smart00712
DNA/RNA-binding repeats in PUR-alpha/beta/gamma and in hypothetical proteins from spirochetes ...
 175-248 6.40e-18

DNA/RNA-binding repeats in PUR-alpha/beta/gamma and in hypothetical proteins from spirochetes and the Bacteroides-Cytophaga-Flexibacter bacteria;


Pssm-ID: 197840 [Multi-domain]  Cd Length: 63  Bit Score: 76.88  E-value: 6.40e-18
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 300796897   175 LKTDYIERDNRKYYLDLKENQRGRFLRIRQTMMRgtgmigyfghslGQEQTIVLPAQGMIEFRDALVQLIEDYG 248
Cdd:smart00712   2 LASKKLTVENKRFYFDVKENRRGRFLRISEVKNN------------GGRSSITVPEQGAAEFRDALTKLIEKYG 63
 
Name Accession Description Interval E-value
PurA pfam04845
PurA ssDNA and RNA-binding protein; This family represents most of the length of the protein.
 61-325 3.10e-122

PurA ssDNA and RNA-binding protein; This family represents most of the length of the protein.


Pssm-ID: 282672 [Multi-domain]  Cd Length: 219  Bit Score: 351.06  E-value: 3.10e-122
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 300796897   61 IQELASKRVDIQKKRFYLDVKQSSRGRFLKIAEVWIGRgrqdniRKSKLTLSLSVAAELKDCLGDFIEHYAHLGlkghRQ 140
Cdd:pfam04845   1 EQELASKRLDIQNKRFYLDVKQNTRGRFIKIAEVGAGG------RKSRITLSMSVAAEFKDELSKFSDHYAQLG----PS 70

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 300796897  141 EHGQSKEQvsrrrqkhsapsppvsvgseehPHSVLKTDYIERDNRKYYLDLKENQRGRFLRIRQTMMRGtgmigyfgHSL 220
Cdd:pfam04845  71 NGEHLPED----------------------GSSLLKSETLVRDNRKYYLDLKENQRGRFLRIAQTPMRG--------NPR 120

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 300796897  221 GQEQTIVLPAQGMIEFRDALVQLIEDYGEGDieerrgGDDDPLELPEGTSFRVDNKRFYFDVGSNKYGIFLKVSEVRPPY 300
Cdd:pfam04845 121 GQRQQIALPAQGMIEFRDALTDLIEDYGEGD------ENDIPQELPEGTSLTVDNKRFYFDVGSNKRGVFLRISEVKPNY 194

                         250       260
                  ....*....|....*....|....*
gi 300796897  301 RNTITVPFKAWTRFGENFIKYEEEM 325
Cdd:pfam04845 195 RNSITVPEKAWTRFRDIFDKYIEKM 219
PUR smart00712
DNA/RNA-binding repeats in PUR-alpha/beta/gamma and in hypothetical proteins from spirochetes ...
 175-248 6.40e-18

DNA/RNA-binding repeats in PUR-alpha/beta/gamma and in hypothetical proteins from spirochetes and the Bacteroides-Cytophaga-Flexibacter bacteria;


Pssm-ID: 197840 [Multi-domain]  Cd Length: 63  Bit Score: 76.88  E-value: 6.40e-18
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 300796897   175 LKTDYIERDNRKYYLDLKENQRGRFLRIRQTMMRgtgmigyfghslGQEQTIVLPAQGMIEFRDALVQLIEDYG 248
Cdd:smart00712   2 LASKKLTVENKRFYFDVKENRRGRFLRISEVKNN------------GGRSSITVPEQGAAEFRDALTKLIEKYG 63
PUR smart00712
DNA/RNA-binding repeats in PUR-alpha/beta/gamma and in hypothetical proteins from spirochetes ...
 265-325 2.76e-16

DNA/RNA-binding repeats in PUR-alpha/beta/gamma and in hypothetical proteins from spirochetes and the Bacteroides-Cytophaga-Flexibacter bacteria;


Pssm-ID: 197840 [Multi-domain]  Cd Length: 63  Bit Score: 72.26  E-value: 2.76e-16
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 300796897   265 LPEGTSFRVDNKRFYFDVGSNKYGIFLKVSEVRP-PYRNTITVPFKAWTRFGENFIKYEEEM 325
Cdd:smart00712   1 ELASKKLTVENKRFYFDVKENRRGRFLRISEVKNnGGRSSITVPEQGAAEFRDALTKLIEKY 62
PUR smart00712
DNA/RNA-binding repeats in PUR-alpha/beta/gamma and in hypothetical proteins from spirochetes ...
 63-131 5.04e-16

DNA/RNA-binding repeats in PUR-alpha/beta/gamma and in hypothetical proteins from spirochetes and the Bacteroides-Cytophaga-Flexibacter bacteria;


Pssm-ID: 197840 [Multi-domain]  Cd Length: 63  Bit Score: 71.49  E-value: 5.04e-16
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 300796897    63 ELASKRVDIQKKRFYLDVKQSSRGRFLKIAEVWIGRGRqdnirkSKLTLSLSVAAELKDCLGDFIEHYA 131
Cdd:smart00712   1 ELASKKLTVENKRFYFDVKENRRGRFLRISEVKNNGGR------SSITVPEQGAAEFRDALTKLIEKYG 63
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH