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Conserved domains on  [gi|312434031|ref|NP_001182487|]
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leucine-rich repeat-containing protein 58 [Rattus norvegicus]

Protein Classification

leucine-rich repeat domain-containing protein( domain architecture ID 11469232)

leucine-rich repeat (LRR) domain-containing protein may participate in protein-protein interactions

Gene Ontology:  GO:0005515
PubMed:  11751054|7583641|14747988
SCOP:  4003523

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
4-242 2.47e-34

Leucine-rich repeat (LRR) protein [Transcription];


:

Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 130.82  E-value: 2.47e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312434031   4 AALGEAELNWSRLSVSAEALESELEARAEERRGSREALLRLLLPYNRLTSLPRALGSGFPHLQLLDVSGNaltalgPELL 83
Cdd:COG4886   37 LLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSLLLLGLTDLGDLTNLTELDLSGN------EELS 110

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312434031  84 TLSGLRTLLARNNRLGgpgSLPKGLGQsplCRSLQVLNLSGNCFQELPASLLELRALQTLSLGGNQLQSIPAEIENLQSL 163
Cdd:COG4886  111 NLTNLESLDLSGNQLT---DLPEELAN---LTNLKELDLSNNQLTDLPEPLGNLTNLKSLDLSNNQLTDLPEELGNLTNL 184

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 312434031 164 ECLYLGGNFIKEIPPELANLPSLNYLVLCDNKIQSVPPQLSQLHSLRSLSLHNNLLTYLPrEILNLIHLEELSLRGNPL 242
Cdd:COG4886  185 KELDLSNNQITDLPEPLGNLTNLEELDLSGNQLTDLPEPLANLTNLETLDLSNNQLTDLP-ELGNLTNLEELDLSNNQL 262
 
Name Accession Description Interval E-value
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
4-242 2.47e-34

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 130.82  E-value: 2.47e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312434031   4 AALGEAELNWSRLSVSAEALESELEARAEERRGSREALLRLLLPYNRLTSLPRALGSGFPHLQLLDVSGNaltalgPELL 83
Cdd:COG4886   37 LLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSLLLLGLTDLGDLTNLTELDLSGN------EELS 110

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312434031  84 TLSGLRTLLARNNRLGgpgSLPKGLGQsplCRSLQVLNLSGNCFQELPASLLELRALQTLSLGGNQLQSIPAEIENLQSL 163
Cdd:COG4886  111 NLTNLESLDLSGNQLT---DLPEELAN---LTNLKELDLSNNQLTDLPEPLGNLTNLKSLDLSNNQLTDLPEELGNLTNL 184

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 312434031 164 ECLYLGGNFIKEIPPELANLPSLNYLVLCDNKIQSVPPQLSQLHSLRSLSLHNNLLTYLPrEILNLIHLEELSLRGNPL 242
Cdd:COG4886  185 KELDLSNNQITDLPEPLGNLTNLEELDLSGNQLTDLPEPLANLTNLETLDLSNNQLTDLP-ELGNLTNLEELDLSNNQL 262
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 61-242 2.41e-18

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 86.83  E-value: 2.41e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312434031  61 GFPHLQLLDVSGNALTALGPE--LLTLSGLRTLLARNNRLGGP---GSLPkGL-----------GQSP----LCRSLQVL 120
Cdd:PLN00113  91 RLPYIQTINLSNNQLSGPIPDdiFTTSSSLRYLNLSNNNFTGSiprGSIP-NLetldlsnnmlsGEIPndigSFSSLKVL 169

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312434031 121 NLSGNCFQ-ELPASLLELRALQTLSLGGNQLQ-SIPAEIENLQSLECLYLG-GNFIKEIPPELANLPSLNYLVLC-DNKI 196
Cdd:PLN00113 170 DLGGNVLVgKIPNSLTNLTSLEFLTLASNQLVgQIPRELGQMKSLKWIYLGyNNLSGEIPYEIGGLTSLNHLDLVyNNLT 249

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*..
gi 312434031 197 QSVPPQLSQLHSLRSLSLHNNLLT-YLPREILNLIHLEELSLRGNPL 242
Cdd:PLN00113 250 GPIPSSLGNLKNLQYLFLYQNKLSgPIPPSIFSLQKLISLDLSDNSL 296
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 113-242 2.43e-12

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 65.58  E-value: 2.43e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312434031 113 LCRSLQVLNLSGNCFQELPaSLLELRALQTLSLGGNQLQSIPaEIENLQSLECLYLGGNFIKEI---------------- 176
Cdd:cd21340   22 LCKNLKVLYLYDNKITKIE-NLEFLTNLTHLYLQNNQIEKIE-NLENLVNLKKLYLGGNRISVVeglenltnleelhien 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312434031 177 ---PPE---------LANL-PSLNYLVLCDNKIQSVPPqLSQLHSLRSLSLHNNLLTYLpREILNLI----HLEELSLRG 239
Cdd:cd21340  100 qrlPPGekltfdprsLAALsNSLRVLNISGNNIDSLEP-LAPLRNLEQLDASNNQISDL-EELLDLLsswpSLRELDLTG 177


                 ...
gi 312434031 240 NPL 242
Cdd:cd21340  178 NPV 180
LRR_8 pfam13855
Leucine rich repeat;
184-242 5.03e-07

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 46.36  E-value: 5.03e-07
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 312434031  184 PSLNYLVLCDNKIQSVPPQ-LSQLHSLRSLSLHNNLLTYL-PREILNLIHLEELSLRGNPL 242
Cdd:pfam13855   1 PNLRSLDLSNNRLTSLDDGaFKGLSNLKVLDLSNNLLTTLsPGAFSGLPSLRYLDLSGNRL 61
 
Name Accession Description Interval E-value
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
4-242 2.47e-34

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 130.82  E-value: 2.47e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312434031   4 AALGEAELNWSRLSVSAEALESELEARAEERRGSREALLRLLLPYNRLTSLPRALGSGFPHLQLLDVSGNaltalgPELL 83
Cdd:COG4886   37 LLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSLLLLGLTDLGDLTNLTELDLSGN------EELS 110

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312434031  84 TLSGLRTLLARNNRLGgpgSLPKGLGQsplCRSLQVLNLSGNCFQELPASLLELRALQTLSLGGNQLQSIPAEIENLQSL 163
Cdd:COG4886  111 NLTNLESLDLSGNQLT---DLPEELAN---LTNLKELDLSNNQLTDLPEPLGNLTNLKSLDLSNNQLTDLPEELGNLTNL 184

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 312434031 164 ECLYLGGNFIKEIPPELANLPSLNYLVLCDNKIQSVPPQLSQLHSLRSLSLHNNLLTYLPrEILNLIHLEELSLRGNPL 242
Cdd:COG4886  185 KELDLSNNQITDLPEPLGNLTNLEELDLSGNQLTDLPEPLANLTNLETLDLSNNQLTDLP-ELGNLTNLEELDLSNNQL 262
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
39-282 3.09e-33

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 127.74  E-value: 3.09e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312434031  39 EALLRLLLPYNRLTSLPRALGSgFPHLQLLDVSGNALTALGPELLTLSGLRTLLARNNRLGgpgSLPKGLGQsplCRSLQ 118
Cdd:COG4886  113 TNLESLDLSGNQLTDLPEELAN-LTNLKELDLSNNQLTDLPEPLGNLTNLKSLDLSNNQLT---DLPEELGN---LTNLK 185

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312434031 119 VLNLSGNCFQELPASLLELRALQTLSLGGNQLQSIPAEIENLQSLECLYLGGNFIKEIPpELANLPSLNYLVLCDNKIQS 198
Cdd:COG4886  186 ELDLSNNQITDLPEPLGNLTNLEELDLSGNQLTDLPEPLANLTNLETLDLSNNQLTDLP-ELGNLTNLEELDLSNNQLTD 264

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312434031 199 VPPqLSQLHSLRSLSLHNNLLTYLPREILNLIHLEELSLRGNPLVVRFVRDLTYDPPTLLELAARTIKIRSISYTPYDLP 278
Cdd:COG4886  265 LPP-LANLTNLKTLDLSNNQLTDLKLKELELLLGLNSLLLLLLLLNLLELLILLLLLTTLLLLLLLLKGLLVTLTTLALS 343


                 ....
gi 312434031 279 GNLL 282
Cdd:COG4886  344 LSLL 347
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 61-242 2.41e-18

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 86.83  E-value: 2.41e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312434031  61 GFPHLQLLDVSGNALTALGPE--LLTLSGLRTLLARNNRLGGP---GSLPkGL-----------GQSP----LCRSLQVL 120
Cdd:PLN00113  91 RLPYIQTINLSNNQLSGPIPDdiFTTSSSLRYLNLSNNNFTGSiprGSIP-NLetldlsnnmlsGEIPndigSFSSLKVL 169

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312434031 121 NLSGNCFQ-ELPASLLELRALQTLSLGGNQLQ-SIPAEIENLQSLECLYLG-GNFIKEIPPELANLPSLNYLVLC-DNKI 196
Cdd:PLN00113 170 DLGGNVLVgKIPNSLTNLTSLEFLTLASNQLVgQIPRELGQMKSLKWIYLGyNNLSGEIPYEIGGLTSLNHLDLVyNNLT 249

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*..
gi 312434031 197 QSVPPQLSQLHSLRSLSLHNNLLT-YLPREILNLIHLEELSLRGNPL 242
Cdd:PLN00113 250 GPIPSSLGNLKNLQYLFLYQNKLSgPIPPSIFSLQKLISLDLSDNSL 296
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 62-242 6.20e-16

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 79.51  E-value: 6.20e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312434031  62 FPHLQLLDVSGNALTA-LGPELLTLSGLRTLLARNNRLGGPgsLPKGLgqSPLCRSLQVLNLSGNCFQ-ELPASLLELra 139
Cdd:PLN00113  68 SSRVVSIDLSGKNISGkISSAIFRLPYIQTINLSNNQLSGP--IPDDI--FTTSSSLRYLNLSNNNFTgSIPRGSIPN-- 141

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312434031 140 LQTLSLGGNQLQ-SIPAEIENLQSLECLYLGGNFIK-EIPPELANLPSLNYLVLCDNK-IQSVPPQLSQLHSLRSLSL-H 215
Cdd:PLN00113 142 LETLDLSNNMLSgEIPNDIGSFSSLKVLDLGGNVLVgKIPNSLTNLTSLEFLTLASNQlVGQIPRELGQMKSLKWIYLgY 221

                        170       180
                 ....*....|....*....|....*..
gi 312434031 216 NNLLTYLPREILNLIHLEELSLRGNPL 242
Cdd:PLN00113 222 NNLSGEIPYEIGGLTSLNHLDLVYNNL 248
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 113-242 2.43e-12

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 65.58  E-value: 2.43e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312434031 113 LCRSLQVLNLSGNCFQELPaSLLELRALQTLSLGGNQLQSIPaEIENLQSLECLYLGGNFIKEI---------------- 176
Cdd:cd21340   22 LCKNLKVLYLYDNKITKIE-NLEFLTNLTHLYLQNNQIEKIE-NLENLVNLKKLYLGGNRISVVeglenltnleelhien 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312434031 177 ---PPE---------LANL-PSLNYLVLCDNKIQSVPPqLSQLHSLRSLSLHNNLLTYLpREILNLI----HLEELSLRG 239
Cdd:cd21340  100 qrlPPGekltfdprsLAALsNSLRVLNISGNNIDSLEP-LAPLRNLEQLDASNNQISDL-EELLDLLsswpSLRELDLTG 177


                 ...
gi 312434031 240 NPL 242
Cdd:cd21340  178 NPV 180
PRK15387 PRK15387
type III secretion system effector E3 ubiquitin transferase SspH2;
44-254 3.12e-12

type III secretion system effector E3 ubiquitin transferase SspH2;


Pssm-ID: 185285 [Multi-domain]  Cd Length: 788  Bit Score: 67.88  E-value: 3.12e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312434031  44 LLLPYNRLTSLPrALGsgfPHLQLLDVSGNALTALG---PELLTLS--------------GLRTLLARNNRLGGPGSLPK 106
Cdd:PRK15387 227 LVIPDNNLTSLP-ALP---PELRTLEVSGNQLTSLPvlpPGLLELSifsnplthlpalpsGLCKLWIFGNQLTSLPVLPP 302

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312434031 107 GLgqsplcrslQVLNLSGNCFQELPASLLEL-----------------RALQTLSLGGNQLQSIP---AEIENL------ 160
Cdd:PRK15387 303 GL---------QELSVSDNQLASLPALPSELcklwaynnqltslptlpSGLQELSVSDNQLASLPtlpSELYKLwaynnr 373

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312434031 161 --------QSLECLYLGGNFIKEIPPelanLPS-LNYLVLCDNKIQSVPPQLSqlhSLRSLSLHNNLLTYLPREILNLIH 231
Cdd:PRK15387 374 ltslpalpSGLKELIVSGNRLTSLPV----LPSeLKELMVSGNRLTSLPMLPS---GLLSLSVYRNQLTRLPESLIHLSS 446

                        250       260
                 ....*....|....*....|....*.
gi 312434031 232 LEELSLRGNPL---VVRFVRDLTYDP 254
Cdd:PRK15387 447 ETTVNLEGNPLserTLQALREITSAP 472
PRK15370 PRK15370
type III secretion system effector E3 ubiquitin transferase SlrP;
40-208 5.11e-12

type III secretion system effector E3 ubiquitin transferase SlrP;


Pssm-ID: 185268 [Multi-domain]  Cd Length: 754  Bit Score: 67.03  E-value: 5.11e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312434031  40 ALLRLLLPYNRLTSLPRALGSGfphLQLLDVSGNALTALgPELLTlSGLRTLLARNNRLGG-PGSLPKGlgqsplcrsLQ 118
Cdd:PRK15370 263 ALQSLDLFHNKISCLPENLPEE---LRYLSVYDNSIRTL-PAHLP-SGITHLNVQSNSLTAlPETLPPG---------LK 328

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312434031 119 VLNLSGNCFQELPASLLElrALQTLSLGGNQLQSIPAEIEnlQSLECLYLGGNFIKEIPpelANLP-SLNYLVLCDNKIQ 197
Cdd:PRK15370 329 TLEAGENALTSLPASLPP--ELQVLDVSKNQITVLPETLP--PTITTLDVSRNALTNLP---ENLPaALQIMQASRNNLV 401

                        170
                 ....*....|.
gi 312434031 198 SVPPQLSQLHS 208
Cdd:PRK15370 402 RLPESLPHFRG 412
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
41-267 2.60e-11

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 64.57  E-value: 2.60e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312434031  41 LLRLLLPYNRLTSLPRALGsGFPHLQLLDVSGNALTALGPELLTLSGLRTLLARNNRLGgpgSLPkGLGQSPlcrSLQVL 120
Cdd:COG4886  184 LKELDLSNNQITDLPEPLG-NLTNLEELDLSGNQLTDLPEPLANLTNLETLDLSNNQLT---DLP-ELGNLT---NLEEL 255

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312434031 121 NLSGNCFQELPaSLLELRALQTLSLGGNQLQSIpaEIENLQSLECLYLGGNFIKEIPPELANLPSLNYLVLCDNKIQSVP 200
Cdd:COG4886  256 DLSNNQLTDLP-PLANLTNLKTLDLSNNQLTDL--KLKELELLLGLNSLLLLLLLLNLLELLILLLLLTTLLLLLLLLKG 332

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 312434031 201 PQLSQLHSLRSLSLHNNLLTYLPREILNLIHLEELSLRGNPLVVRFVRDLTYDPPTLLELAARTIKI 267
Cdd:COG4886  333 LLVTLTTLALSLSLLALLTLLLLLNLLSLLLTLLLTLGLLGLLEATLLTLALLLLTLLLLLLTTTAG 399
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 35-242 3.54e-10

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 61.40  E-value: 3.54e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312434031  35 RGSREALLRLLLPYNRLT-SLPRALGSgFPHLQLLDVSGNALTALGPELLT-LSGLRTLLARNNRLggPGSLPKGLGQsp 112
Cdd:PLN00113 136 RGSIPNLETLDLSNNMLSgEIPNDIGS-FSSLKVLDLGGNVLVGKIPNSLTnLTSLEFLTLASNQL--VGQIPRELGQ-- 210

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312434031 113 lCRSLQVL-----NLSG--------------------NCFQELPASLLELRALQTLSLGGNQLQ---------------- 151
Cdd:PLN00113 211 -MKSLKWIylgynNLSGeipyeiggltslnhldlvynNLTGPIPSSLGNLKNLQYLFLYQNKLSgpippsifslqklisl 289

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312434031 152 ---------SIPAEIENLQSLECLYL-GGNFIKEIPPELANLPSLNYLVLCDNKIQ-SVPPQLSQLHSLRSLSLHNNLLT 220
Cdd:PLN00113 290 dlsdnslsgEIPELVIQLQNLEILHLfSNNFTGKIPVALTSLPRLQVLQLWSNKFSgEIPKNLGKHNNLTVLDLSTNNLT 369

                        250       260
                 ....*....|....*....|...
gi 312434031 221 -YLPREILNLIHLEELSLRGNPL 242
Cdd:PLN00113 370 gEIPEGLCSSGNLFKLILFSNSL 392
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 44-242 1.42e-09

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 59.86  E-value: 1.42e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312434031  44 LLLPYNRLT-SLPRALGSGfPHLQLLDVSGNALTALGPELLTLSG-LRTLLARNNRLggPGSLPKGLGQsplCRSLQVLN 121
Cdd:PLN00113 337 LQLWSNKFSgEIPKNLGKH-NNLTVLDLSTNNLTGEIPEGLCSSGnLFKLILFSNSL--EGEIPKSLGA---CRSLRRVR 410

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312434031 122 LSGNCFQ-ELPASLLELRALQTLSLGGNQLQ-SIPAEIENLQSLECLYLGGN------------------------FIKE 175
Cdd:PLN00113 411 LQDNSFSgELPSEFTKLPLVYFLDISNNNLQgRINSRKWDMPSLQMLSLARNkffgglpdsfgskrlenldlsrnqFSGA 490

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 312434031 176 IPPELANLPSLNYLVLCDNKIQSV-PPQLSQLHSLRSLSL-HNNLLTYLPREILNLIHLEELSLRGNPL 242
Cdd:PLN00113 491 VPRKLGSLSELMQLKLSENKLSGEiPDELSSCKKLVSLDLsHNQLSGQIPASFSEMPVLSQLDLSQNQL 559
PLN03210 PLN03210
Resistant to P. syringae 6; Provisional
 42-237 5.99e-09

Resistant to P. syringae 6; Provisional


Pssm-ID: 215633 [Multi-domain]  Cd Length: 1153  Bit Score: 57.96  E-value: 5.99e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312434031   42 LRLLlpynRLTSLP-RALGSGF--PHLQLLDVSGNALTALGPELLTLSGLRTLLARnnrlggpGSlpKGLGQSP---LCR 115
Cdd:PLN03210  591 LRLL----RWDKYPlRCMPSNFrpENLVKLQMQGSKLEKLWDGVHSLTGLRNIDLR-------GS--KNLKEIPdlsMAT 657

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312434031  116 SLQVLNLSgNC--FQELPASLLELRALQTLSLGG-NQLQSIPAEIeNLQSLECL---------------------YLGGN 171
Cdd:PLN03210  658 NLETLKLS-DCssLVELPSSIQYLNKLEDLDMSRcENLEILPTGI-NLKSLYRLnlsgcsrlksfpdistniswlDLDET 735

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 312434031  172 FIKEIPPELaNLPSLNYLVLCDNK-------IQSVPPQLSQL-HSLRSLSLHNN-LLTYLPREILNLIHLEELSL 237
Cdd:PLN03210  736 AIEEFPSNL-RLENLDELILCEMKseklwerVQPLTPLMTMLsPSLTRLFLSDIpSLVELPSSIQNLHKLEHLEI 809
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
36-257 3.10e-08

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 54.94  E-value: 3.10e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312434031  36 GSREALLRLLLPYNRLTSLPRALGsGFPHLQLLDVSGNALTALgPELLTLSGLRTLLARNNRLggpgslpKGLGQSPLCR 115
Cdd:COG4886  202 GNLTNLEELDLSGNQLTDLPEPLA-NLTNLETLDLSNNQLTDL-PELGNLTNLEELDLSNNQL-------TDLPPLANLT 272

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312434031 116 SLQVLNLSGNCFQELPASLLELRALQTLSLGGNQLQSIPAEIENLQSLECLYLGGNFIKEIPPELANLPSLNYLVLCDNK 195
Cdd:COG4886  273 NLKTLDLSNNQLTDLKLKELELLLGLNSLLLLLLLLNLLELLILLLLLTTLLLLLLLLKGLLVTLTTLALSLSLLALLTL 352

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 312434031 196 IQSVPPQLSQLHSLRSLSLHNNLLTYLPREILNLIHLEELSLRGNPLVVRFVRDLTYDPPTL 257
Cdd:COG4886  353 LLLLNLLSLLLTLLLTLGLLGLLEATLLTLALLLLTLLLLLLTTTAGVLLLTLALLDAVNTE 414
PLN03150 PLN03150
hypothetical protein; Provisional
 153-220 5.31e-08

hypothetical protein; Provisional


Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 54.44  E-value: 5.31e-08
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312434031 153 IPAEIENLQSLECLYLGGNFIK-EIPPELANLPSLNYLVLCDNKIQ-SVPPQLSQLHSLRSLSLHNNLLT 220
Cdd:PLN03150 434 IPNDISKLRHLQSINLSGNSIRgNIPPSLGSITSLEVLDLSYNSFNgSIPESLGQLTSLRILNLNGNSLS 503
PRK15370 PRK15370
type III secretion system effector E3 ubiquitin transferase SlrP;
10-257 1.06e-07

type III secretion system effector E3 ubiquitin transferase SlrP;


Pssm-ID: 185268 [Multi-domain]  Cd Length: 754  Bit Score: 53.55  E-value: 1.06e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312434031  10 ELNWSRLSVSAEALESELEARAEERRgsREAL----LRLLLPYNRLTSLPRALgsgfphlqlldvsgnaltalgPELLTl 85
Cdd:PRK15370 147 ELIWSEWVKEAPAKEAANREEAVQRM--RDCLknnkTELRLKILGLTTIPACI---------------------PEQIT- 202

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312434031  86 sglrTLLARNNRLGgpgSLPKglgqsplcrslqvlNLSGNcfqelpasllelraLQTLSLGGNQLQSIPAEIENlqSLEC 165
Cdd:PRK15370 203 ----TLILDNNELK---SLPE--------------NLQGN--------------IKTLYANSNQLTSIPATLPD--TIQE 245

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312434031 166 LYLGGNFIKEIPpelANLPS-LNYLVLCDNKIQSVPPQLSQlhSLRSLSLHNNLLTYLPREILNLIhlEELSLRGNplvv 244
Cdd:PRK15370 246 MELSINRITELP---ERLPSaLQSLDLFHNKISCLPENLPE--ELRYLSVYDNSIRTLPAHLPSGI--THLNVQSN---- 314

                        250
                 ....*....|...
gi 312434031 245 rfvrDLTYDPPTL 257
Cdd:PRK15370 315 ----SLTALPETL 323
LRR_8 pfam13855
Leucine rich repeat;
184-242 5.03e-07

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 46.36  E-value: 5.03e-07
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 312434031  184 PSLNYLVLCDNKIQSVPPQ-LSQLHSLRSLSLHNNLLTYL-PREILNLIHLEELSLRGNPL 242
Cdd:pfam13855   1 PNLRSLDLSNNRLTSLDDGaFKGLSNLKVLDLSNNLLTTLsPGAFSGLPSLRYLDLSGNRL 61
LRR_8 pfam13855
Leucine rich repeat;
161-219 6.36e-07

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 45.98  E-value: 6.36e-07
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 312434031  161 QSLECLYLGGNFIKEIPPE-LANLPSLNYLVLCDNKIQSVPPQ-LSQLHSLRSLSLHNNLL 219
Cdd:pfam13855   1 PNLRSLDLSNNRLTSLDDGaFKGLSNLKVLDLSNNLLTTLSPGaFSGLPSLRYLDLSGNRL 61
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 65-242 1.57e-06

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 50.23  E-value: 1.57e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312434031  65 LQLLDVSGNALTALGPELLT-LSGLRTLLARNNRLGGpgSLPKGLGQSplcRSLQVLNLSGNCFQ-ELPASLLELRALQT 142
Cdd:PLN00113 310 LEILHLFSNNFTGKIPVALTsLPRLQVLQLWSNKFSG--EIPKNLGKH---NNLTVLDLSTNNLTgEIPEGLCSSGNLFK 384

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312434031 143 LSLGGNQLQS-IPAEIENLQSLECLYLGGN-FIKEIPPELANLPSLNYLVLCDNKIQ--------SVP------------ 200
Cdd:PLN00113 385 LILFSNSLEGeIPKSLGACRSLRRVRLQDNsFSGELPSEFTKLPLVYFLDISNNNLQgrinsrkwDMPslqmlslarnkf 464

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*..
gi 312434031 201 ----PQLSQLHSLRSLSLHNNLLT-YLPREILNLIHLEELSLRGNPL 242
Cdd:PLN00113 465 fgglPDSFGSKRLENLDLSRNQFSgAVPRKLGSLSELMQLKLSENKL 511
PLN03150 PLN03150
hypothetical protein; Provisional
 115-184 3.45e-06

hypothetical protein; Provisional


Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 49.04  E-value: 3.45e-06
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 312434031 115 RSLQVLNLSGNCFQ-ELPASLLELRALQTLSLGGNQLQ-SIPAEIENLQSLECLYLGGNFIK-EIPPELANLP 184
Cdd:PLN03150 442 RHLQSINLSGNSIRgNIPPSLGSITSLEVLDLSYNSFNgSIPESLGQLTSLRILNLNGNSLSgRVPAALGGRL 514
LRR_8 pfam13855
Leucine rich repeat;
138-196 3.85e-05

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 40.97  E-value: 3.85e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 312434031  138 RALQTLSLGGNQLQSIPAEI-ENLQSLECLYLGGNFIKEIPPE-LANLPSLNYLVLCDNKI 196
Cdd:pfam13855   1 PNLRSLDLSNNRLTSLDDGAfKGLSNLKVLDLSNNLLTTLSPGaFSGLPSLRYLDLSGNRL 61
LRR_8 pfam13855
Leucine rich repeat;
43-98 5.99e-05

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 40.59  E-value: 5.99e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 312434031   43 RLLLPYNRLTSLPRALGSGFPHLQLLDVSGNALTALGPELLT-LSGLRTLLARNNRL 98
Cdd:pfam13855   5 SLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSgLPSLRYLDLSGNRL 61
PRK15370 PRK15370
type III secretion system effector E3 ubiquitin transferase SlrP;
40-112 2.18e-04

type III secretion system effector E3 ubiquitin transferase SlrP;


Pssm-ID: 185268 [Multi-domain]  Cd Length: 754  Bit Score: 43.15  E-value: 2.18e-04
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 312434031  40 ALLRLLLPYNRLTSLPRALGsgfPHLQLLDVSGNALTALgPELLTlSGLRTLLA-RNNRLGGPGSLPKGLGQSP 112
Cdd:PRK15370 347 ELQVLDVSKNQITVLPETLP---PTITTLDVSRNALTNL-PENLP-AALQIMQAsRNNLVRLPESLPHFRGEGP 415
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 51-131 5.40e-04

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 40.92  E-value: 5.40e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312434031  51 LTSLPRALGSGFPHLQLLDVSGNALTALGPeLLTLSGLRTLLARNNRLGGPGSLPKGLGQsplCRSLQVLNLSGNCFQEL 130
Cdd:cd21340  108 LTFDPRSLAALSNSLRVLNISGNNIDSLEP-LAPLRNLEQLDASNNQISDLEELLDLLSS---WPSLRELDLTGNPVCKK 183


                 .
gi 312434031 131 P 131
Cdd:cd21340  184 P 184
PLN03150 PLN03150
hypothetical protein; Provisional
 60-157 9.79e-04

hypothetical protein; Provisional


Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 40.95  E-value: 9.79e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312434031  60 SGFPHLQLLDVSGNALTalgpelltlsglrtllarnnrlggpGSLPKGLGQSPlcrSLQVLNLSGNCFQ-ELPASLLELR 138
Cdd:PLN03150 439 SKLRHLQSINLSGNSIR-------------------------GNIPPSLGSIT---SLEVLDLSYNSFNgSIPESLGQLT 490

                         90       100
                 ....*....|....*....|
gi 312434031 139 ALQTLSLGGNQLQS-IPAEI 157
Cdd:PLN03150 491 SLRILNLNGNSLSGrVPAAL 510
LRR_8 pfam13855
Leucine rich repeat;
115-171 1.73e-03

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 36.35  E-value: 1.73e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 312434031  115 RSLQVLNLSGNCFQELPASLLE-LRALQTLSLGGNQLQSI-PAEIENLQSLECLYLGGN 171
Cdd:pfam13855   1 PNLRSLDLSNNRLTSLDDGAFKgLSNLKVLDLSNNLLTTLsPGAFSGLPSLRYLDLSGN 59
LRR_8 pfam13855
Leucine rich repeat;
86-150 1.89e-03

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 36.35  E-value: 1.89e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 312434031   86 SGLRTLLARNNRLGG-PGSLPKGLgqsplcRSLQVLNLSGNCFQEL-PASLLELRALQTLSLGGNQL 150
Cdd:pfam13855   1 PNLRSLDLSNNRLTSlDDGAFKGL------SNLKVLDLSNNLLTTLsPGAFSGLPSLRYLDLSGNRL 61
RNA1 COG5238
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ...
 38-217 1.90e-03

Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];


Pssm-ID: 444072 [Multi-domain]  Cd Length: 434  Bit Score: 40.16  E-value: 1.90e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312434031  38 REALLRLLLPYNRLTSLpraLGSGFPHLQLLDVSGNALTALGPELLTLSGLRtllarNNRLGGPG--SLPKGLGQSPLCR 115
Cdd:COG5238  140 RINLIQVLKDPLGGNAV---HLLGLAARLGLLAAISMAKALQNNSVETVYLG-----CNQIGDEGieELAEALTQNTTVT 211

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312434031 116 SLQvlnLSGNCFQELPAS-----LLELRALQTLSLGGNQL--QSIPAEIENLQ---SLECLYLGGNFIKE-----IPPEL 180
Cdd:COG5238  212 TLW---LKRNPIGDEGAEilaeaLKGNKSLTTLDLSNNQIgdEGVIALAEALKnntTVETLYLSGNQIGAegaiaLAKAL 288

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|..
gi 312434031 181 ANLPSLNYLVLCDNKI-----QSVPPQLSQLHSLRSLSLHNN 217
Cdd:COG5238  289 QGNTTLTSLDLSVNRIgdegaIALAEGLQGNKTLHTLNLAYN 330
LRR_RI cd00116
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ...
 54-206 1.95e-03

Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).


Pssm-ID: 238064 [Multi-domain]  Cd Length: 319  Bit Score: 39.65  E-value: 1.95e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312434031  54 LPRALGSGFPHLQLLDVSGNALT-----ALGPELLTLSGLRTLLARNNRLGGPG--SLPKGLGQSPlcrSLQVLNLSGNC 126
Cdd:cd00116  128 LAKGLKDLPPALEKLVLGRNRLEgasceALAKALRANRDLKELNLANNGIGDAGirALAEGLKANC---NLEVLDLNNNG 204

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312434031 127 FQELPASLLE-----LRALQTLSLGGNQLQSI------PAEIENLQSLECLYLGGNFIKEIPPE-----LANLPSLNYLV 190
Cdd:cd00116  205 LTDEGASALAetlasLKSLEVLNLGDNNLTDAgaaalaSALLSPNISLLTLSLSCNDITDDGAKdlaevLAEKESLLELD 284

                        170
                 ....*....|....*.
gi 312434031 191 LCDNKIQSVPPQLSQL 206
Cdd:cd00116  285 LRGNKFGEEGAQLLAE 300
LRR_RI cd00116
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ...
 1-240 8.96e-03

Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).


Pssm-ID: 238064 [Multi-domain]  Cd Length: 319  Bit Score: 37.72  E-value: 8.96e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312434031   1 MEEAALGEAELNWSRLSVSAEALESelearaeerrgsREALLRLLLPYNRLTSLPRALGSgfphlqlldvsgnaltaLGP 80
Cdd:cd00116   25 LQVLRLEGNTLGEEAAKALASALRP------------QPSLKELCLSLNETGRIPRGLQS-----------------LLQ 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312434031  81 ELLTLSGLRTLLARNNRLG--GPGSLPKGLGQSPL------------------CRSLQVL------------NLSGNCFQ 128
Cdd:cd00116   76 GLTKGCGLQELDLSDNALGpdGCGVLESLLRSSSLqelklnnnglgdrglrllAKGLKDLppaleklvlgrnRLEGASCE 155

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312434031 129 ELPASLLELRALQTLSLGGNQL--QSIPA-----------EIENLQSLECLYLGGNFIKEIPPELANLPSLNylvLCDNK 195
Cdd:cd00116  156 ALAKALRANRDLKELNLANNGIgdAGIRAlaeglkancnlEVLDLNNNGLTDEGASALAETLASLKSLEVLN---LGDNN 232

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 312434031 196 IQSVPPQ------LSQLHSLRSLSLHNNLLTY-----LPREILNLIHLEELSLRGN 240
Cdd:cd00116  233 LTDAGAAalasalLSPNISLLTLSLSCNDITDdgakdLAEVLAEKESLLELDLRGN 288
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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