|
Name |
Accession |
Description |
Interval |
E-value |
| Cys_Met_Meta_PP |
pfam01053 |
Cys/Met metabolism PLP-dependent enzyme; This family includes enzymes involved in cysteine and ... |
18-394 |
0e+00 |
|
Cys/Met metabolism PLP-dependent enzyme; This family includes enzymes involved in cysteine and methionine metabolism. The following are members: Cystathionine gamma-lyase, Cystathionine gamma-synthase, Cystathionine beta-lyase, Methionine gamma-lyase, OAH/OAS sulfhydrylase, O-succinylhomoserine sulfhydrylase All of these members participate is slightly different reactions. All these enzymes use PLP (pyridoxal-5'-phosphate) as a cofactor.
Pssm-ID: 395837 [Multi-domain] Cd Length: 376 Bit Score: 590.74 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 18 ATQAIHVGQEPEQwSSRAVVLPISLATTFKQDSPGQSSGFVYSRSGNPTRNCLEKAVAALDGAKHCLTFASGLAATT-TI 96
Cdd:pfam01053 1 DTLAVHAGQRPDP-QTGAVSVPIYLTSTYVFDFAGEEGGYDYSRSGNPTRDVLEERIAALEGGAAALAFSSGMAAITaAI 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 97 THLLKAGDEVICMDEVYGGTNRYFRRVASEFGLKISFVDCSKTKLLEAAITPQTKLVWIETPTNPTLKLADIKACAQIVH 176
Cdd:pfam01053 80 LALLKAGDHIVATDDLYGGTYRLFNKVLPRFGIEVTFVDTSDPEDLEAAIKPNTKAVYLETPTNPLLKVVDIEAIAKLAK 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 177 KHKdIILVVDNTFMSAYFQRPLALGADICMCSATKYMNGHSDVVMGLVSVNSDDLNERLRFLQNSLGAVPSPFDCYLCCR 256
Cdd:pfam01053 160 KHG-ILVVVDNTFASPYLQRPLDLGADIVVHSATKYIGGHSDVVGGVIVVNGEELGKELYFLQNATGAVLSPFDAWLLLR 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 257 GLKTLQIRMEKHFRNGMAVARFLESNPRVEKVIYPGLPSHPQHELAKRQCTGCPGMVSFYIKGTLQHAQVFLKNIKLFAL 336
Cdd:pfam01053 239 GLKTLGLRMEQHQENAQKVAEFLESHPKVEKVYYPGLPSHPGHELAKRQMKGFGGMLSFELKGGLEAAKKFLDNLKLFSL 318
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*...
gi 1938958469 337 AESLGGYESLAELPAIMTHASVPEKDRATLGISDTLIRLSVGLEDEKDLLEDLGQALK 394
Cdd:pfam01053 319 AVSLGGVESLISHPATMTHASIPPEEREAAGITDDLIRLSVGIEDVDDLIADLKQALE 376
|
|
| MetC |
COG0626 |
Cystathionine beta-lyase/cystathionine gamma-synthase [Amino acid transport and metabolism]; ... |
15-396 |
0e+00 |
|
Cystathionine beta-lyase/cystathionine gamma-synthase [Amino acid transport and metabolism]; Cystathionine beta-lyase/cystathionine gamma-synthase is part of the Pathway/BioSystem: Methionine biosynthesis
Pssm-ID: 440391 [Multi-domain] Cd Length: 389 Bit Score: 587.79 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 15 QHFATQAIHVGQEPEqWSSRAVVLPISLATTFKQDSPGQ--------SSGFVYSRSGNPTRNCLEKAVAALDGAKHCLTF 86
Cdd:COG0626 1 MGPATRAVHAGRDPD-PQTGAVSPPIYLTSTFVFPSAEAlaarfageEGGYIYSRYGNPTRRALEEALAALEGGEAALAF 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 87 ASGLAA-TTTITHLLKAGDEVICMDEVYGGTNRYFRRVASEFGLKISFVDCSKTKLLEAAITPQTKLVWIETPTNPTLKL 165
Cdd:COG0626 80 ASGMAAiSAVLLALLKAGDHVVASDDLYGGTRRLLDKVLARFGIEVTFVDPTDLAAVEAAIRPNTKLVFLETPSNPTLEV 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 166 ADIKACAQIVHKHkDIILVVDNTFMSAYFQRPLALGADICMCSATKYMNGHSDVVMGLVSVNSDDLNERLRFLQNSLGAV 245
Cdd:COG0626 160 VDIAAIAAIAHAA-GALLVVDNTFATPLLQRPLELGADIVVHSATKYLGGHSDVLGGAVVGRDEELAERLRFLQNALGAV 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 246 PSPFDCYLCCRGLKTLQIRMEKHFRNGMAVARFLESNPRVEKVIYPGLPSHPQHELAKRQCTGCPGMVSFYIKGTLQHAQ 325
Cdd:COG0626 239 LSPFDAWLLLRGLKTLALRMERHCENALAVAEWLEAHPAVARVYYPGLPSHPGHELAKRQMSGFGGMLSFELKGGREAAR 318
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1938958469 326 VFLKNIKLFALAESLGGYESLAELPAIMTHASVPEKDRATLGISDTLIRLSVGLEDEKDLLEDLGQALKAA 396
Cdd:COG0626 319 RFLDALKLFTLAVSLGGVESLITHPATMTHRSLPPEERAALGITDGLVRLSVGLEDVDDLIADLEQALAAL 389
|
|
| CGS_like |
cd00614 |
CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed ... |
35-394 |
0e+00 |
|
CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of antimicrobials and herbicides. This subgroup also includes cystathionine gamma-lyases (CGL), O-acetylhomoserine sulfhydrylases and O-acetylhomoserine thiol lyases. CGL's are very similar to CGS's. Members of this group are widely distributed among all three forms of life.
Pssm-ID: 99738 [Multi-domain] Cd Length: 369 Bit Score: 556.82 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 35 AVVLPISLATTFKQDSP--------GQSSGFVYSRSGNPTRNCLEKAVAALDGAKHCLTFASGLAA-TTTITHLLKAGDE 105
Cdd:cd00614 2 AVAPPIYQTSTFVFPSPaeaadlfaLREGGYIYSRIGNPTVDALEKKLAALEGGEAALAFSSGMAAiSTVLLALLKAGDH 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 106 VICMDEVYGGTNRYFRRVASEFGLKISFVDCSKTKLLEAAITPQTKLVWIETPTNPTLKLADIKACAQIVHKHkDIILVV 185
Cdd:cd00614 82 VVASDDLYGGTYRLFERLLPKLGIEVTFVDPDDPEALEAAIKPETKLVYVESPTNPTLKVVDIEAIAELAHEH-GALLVV 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 186 DNTFMSAYFQRPLALGADICMCSATKYMNGHSDVVMGLVSVNSDDLNERLRFLQNSLGAVPSPFDCYLCCRGLKTLQIRM 265
Cdd:cd00614 161 DNTFATPYLQRPLELGADIVVHSATKYIGGHSDVIAGVVVGSGEALIQRLRFLRLALGTILSPFDAWLLLRGLKTLPLRM 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 266 EKHFRNGMAVARFLESNPRVEKVIYPGLPSHPQHELAKRQCTGCPGMVSFYIKGTLQHAQVFLKNIKLFALAESLGGYES 345
Cdd:cd00614 241 ERHSENALKVAEFLEKHPKVERVYYPGLPSHPQHELAKKQMSGYGGVFSFELKGGLEAAKKFLNALKLFSLAVSLGGVES 320
|
330 340 350 360
....*....|....*....|....*....|....*....|....*....
gi 1938958469 346 LAELPAIMTHASVPEKDRATLGISDTLIRLSVGLEDEKDLLEDLGQALK 394
Cdd:cd00614 321 LVEHPASMTHSQLPPEERAAAGITPGLVRLSVGIEDVEDLIADLEQALK 369
|
|
| PRK07811 |
PRK07811 |
cystathionine gamma-synthase; Provisional |
12-395 |
6.90e-172 |
|
cystathionine gamma-synthase; Provisional
Pssm-ID: 236104 [Multi-domain] Cd Length: 388 Bit Score: 485.30 E-value: 6.90e-172
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 12 PSFQHFATQAIHVGQEPEQWSSrAVVLPISLATTFKQDSPGQ-SSGFVYSRSGNPTRNCLEKAVAALDGAKHCLTFASGL 90
Cdd:PRK07811 8 HANQGFATRAIHAGYEPDPATG-AVNPPIYASSTFAQDGVGGlRGGYEYARTGNPTRTALEEQLAALEGGAYGRAFSSGM 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 91 AAT-TTITHLLKAGDEVICMDEVYGGTNRYFRRVASEFGLKISFVDCSKTKLLEAAITPQTKLVWIETPTNPTLKLADIK 169
Cdd:PRK07811 87 AATdCLLRAVLRPGDHIVIPNDAYGGTFRLIDKVFTRWGVEYTPVDLSDLDAVRAAITPRTKLIWVETPTNPLLSITDIA 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 170 ACAQIVHKHkDIILVVDNTFMSAYFQRPLALGADICMCSATKYMNGHSDVVMGLVSVNSDDLNERLRFLQNSLGAVPSPF 249
Cdd:PRK07811 167 ALAELAHDA-GAKVVVDNTFASPYLQQPLALGADVVVHSTTKYIGGHSDVVGGALVTNDEELDEAFAFLQNGAGAVPGPF 245
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 250 DCYLCCRGLKTLQIRMEKHFRNGMAVARFLESNPRVEKVIYPGLPSHPQHELAKRQCTGCPGMVSFYIKGTLQHAQVFLK 329
Cdd:PRK07811 246 DAYLTLRGLKTLAVRMDRHSENAEAVAEFLAGHPEVSTVLYPGLPSHPGHEVAARQMRGFGGMVSVRLAGGEEAARDFCA 325
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1938958469 330 NIKLFALAESLGGYESLAELPAIMTHASVPEkdrATLGISDTLIRLSVGLEDEKDLLEDLGQALKA 395
Cdd:PRK07811 326 RTKVFTLAESLGGVESLIEHPSAMTHASTAG---SQLEVPDDLVRLSVGIEDVADLLADLEQALGQ 388
|
|
| PRK07671 |
PRK07671 |
bifunctional cystathionine gamma-lyase/homocysteine desulfhydrase; |
19-394 |
9.63e-158 |
|
bifunctional cystathionine gamma-lyase/homocysteine desulfhydrase;
Pssm-ID: 181076 [Multi-domain] Cd Length: 377 Bit Score: 448.79 E-value: 9.63e-158
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 19 TQAIHVGQEPEQwSSRAVVLPISLATTFKQDSPGQSSGFVYSRSGNPTRNCLEKAVAALDGAKHCLTFASGLAATTTITH 98
Cdd:PRK07671 5 TKLIHGGIIGDP-STGAVSVPIYQVSTYKQEAVGKHQGYEYSRTGNPTRAALEELIAVLEGGHAGFAFGSGMAAITAVMM 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 99 LLKAGDEVICMDEVYGGTNRYFRRVASEFGLKISFVDCSKTKLLEAAITPQTKLVWIETPTNPTLKLADIKACAQIVHKH 178
Cdd:PRK07671 84 LFSSGDHVILTDDVYGGTYRVMTKVLNRFGIEHTFVDTSNLEEVEEAIRPNTKAIYVETPTNPLLKITDIKKISTIAKEK 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 179 kDIILVVDNTFMSAYFQRPLALGADICMCSATKYMNGHSDVVMGLVSVNSDDLNERLRFLQNSLGAVPSPFDCYLCCRGL 258
Cdd:PRK07671 164 -GLLTIVDNTFMTPYWQSPISLGADIVLHSATKYLGGHSDVVAGLVVVNSPELAEDLHFVQNSTGGILGPQDSWLLLRGL 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 259 KTLQIRMEKHFRNGMAVARFLESNPRVEKVIYPGLPSHPQHELAKRQCTGCPGMVSFYIkGTLQHAQVFLKNIKLFALAE 338
Cdd:PRK07671 243 KTLGIRMEEHETNSRAIAEFLNNHPAVNKVYYPGLPSHPNHELAKEQANGFGGMISFDV-GSEETANKVLERLQYFTLAE 321
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*.
gi 1938958469 339 SLGGYESLAELPAIMTHASVPEKDRATLGISDTLIRLSVGLEDEKDLLEDLGQALK 394
Cdd:PRK07671 322 SLGAVESLISIPSQMTHASIPADRRKELGITDGLIRISVGIEDGEDLIEDLAQALA 377
|
|
| PRK06176 |
PRK06176 |
cystathionine gamma-synthase; |
16-395 |
1.07e-143 |
|
cystathionine gamma-synthase;
Pssm-ID: 180443 [Multi-domain] Cd Length: 380 Bit Score: 413.52 E-value: 1.07e-143
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 16 HFATQAIHvGQEPEQWSSRAVVLPISLATTFKQDSPGQSSGFVYSRSGNPTRNCLEKAVAALDGAKHCLTFASGLAATTT 95
Cdd:PRK06176 2 RMQTKLIH-GGISEDTTTGAVSVPIYQTSTYRQDAIGRPKGYEYSRSGNPTRFALEELIADLEGGVKGFAFASGLAGIHA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 96 ITHLLKAGDEVICMDEVYGGTNRYFRRVASEFGLKISFVDCSKTKLLEAAITPQTKLVWIETPTNPTLKLADIKACAQIV 175
Cdd:PRK06176 81 VFSLFQSGDHVLLGDDVYGGTFRLFDKVLVKNGLSCTIIDTSDLSQIKKAIKPNTKALYLETPSNPLLKITDLAQCASVA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 176 HKHkDIILVVDNTFMSAYFQRPLALGADICMCSATKYMNGHSDVVMGLVSVNSDDLNERLRFLQNSLGAVPSPFDCYLCC 255
Cdd:PRK06176 161 KDH-GLLTIVDNTFATPYYQNPLLLGADIVVHSGTKYLGGHSDVVAGLVTTNNEALAQEIAFFQNAIGGVLGPQDSWLLQ 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 256 RGLKTLQIRMEKHFRNGMAVARFLESNPRVEKVIYPGLPSHPQHELAKRQCTGCPGMVSFYIKGTLQhAQVFLKNIKLFA 335
Cdd:PRK06176 240 RGIKTLGLRMEAHQKNALCVAEFLEKHPKVEKVYYPGLPTHPNHELAKKQMRGFSGMLSFTLKNDSE-AVAFVESLKLFI 318
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 336 LAESLGGYESLAELPAIMTHASVPEKDRATLGISDTLIRLSVGLEDEKDLLEDLGQALKA 395
Cdd:PRK06176 319 LGESLGGVESLVGIPAFMTHACIPKEQREAAGIRDGLVRLSVGIEHEQDLLEDLEQAFAK 378
|
|
| cysta_beta_ly_E |
TIGR01329 |
cystathionine beta-lyase, eukaryotic; This model represents cystathionine beta-lyase ... |
18-396 |
6.10e-134 |
|
cystathionine beta-lyase, eukaryotic; This model represents cystathionine beta-lyase (alternate name: beta-cystathionase), one of several pyridoxal-dependent enzymes of cysteine, methionine, and homocysteine metabolism. This enzyme is involved in the biosynthesis of Met from Cys.
Pssm-ID: 273557 [Multi-domain] Cd Length: 378 Bit Score: 388.42 E-value: 6.10e-134
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 18 ATQAIHVGQEPEQWSsrAVVLPISLATTFKQDSPGQSSGFVYSRSGNPTRNCLEKAVAALDGAKHCLTFASGLAATTTIT 97
Cdd:TIGR01329 2 STLLVNTDNKNDPYD--ASSMPIYQTATFKQPLAIENGPYDYTRSGNPTRTALESLLAKLDKADRAFAFSSGMAALDVIT 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 98 HLLKAGDEVICMDEVYGGTNRYFRRVASEFGLKISFVDCSKTKLLEAAITPQTKLVWIETPTNPTLKLADIKACAQIVHK 177
Cdd:TIGR01329 80 RLLNNGDEIIAGDDLYGGTDRLLTQVVPRSGVVVVHVDTTDLDKVKAALGPKTKLVLLESPTNPLQKIVDIRKISEMAHA 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 178 HkDIILVVDNTFMSAYFQRPLALGADICMCSATKYMNGHSDVVMGLVSVNSDDLNERLRFLQNSLGAVPSPFDCYLCCRG 257
Cdd:TIGR01329 160 Q-NALVVVDNTMMSPLLCNPLELGADIVYHSATKFLAGHSDVMAGVLAVKGEEIAKKVYFLQNSTGSGLAPFDCWLLLRG 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 258 LKTLQIRMEKHFRNGMAVARFLESNPRVEKVIYPGLPSHPQHELAKRQCTGcPGMVSFYIKGTLQHAQVFLKNIKLFALA 337
Cdd:TIGR01329 239 IKTLAIRIEKQQENARAIAMFLSTHPRVKKVRYAGLPSHPGFHLHFSQAKG-AGSVLSFETGSVALSKRLVEATKLFSIT 317
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*....
gi 1938958469 338 ESLGGYESLAELPAIMTHASVPEKDRATLGISDTLIRLSVGLEDEKDLLEDLGQALKAA 396
Cdd:TIGR01329 318 VSFGSVNSLISMPCFMSHASIPAEVREERGLPEDLVRLSVGIEDVDDLISDLDIAFVTA 376
|
|
| PRK06234 |
PRK06234 |
methionine gamma-lyase; Provisional |
17-393 |
6.80e-131 |
|
methionine gamma-lyase; Provisional
Pssm-ID: 168478 [Multi-domain] Cd Length: 400 Bit Score: 381.48 E-value: 6.80e-131
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 17 FATQAIHVGQEPE-QWSSRAVvlPISLATTFKQDSP--------GQSSGFVYSRSGNPTRNCLEKAVAALDGAKHCLTFA 87
Cdd:PRK06234 9 FATKAIHGGHIGDkQFGSLAT--PIYQTSTFIFDSAeqggrrfaGEESGYIYSRLGNPTSTEVENKLALLEGGEAAVVAA 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 88 SGLAA-TTTITHLLKAGDEVICMDEVYGGTNRYFRRVASEFGLKISFVDCSKTKLLEAAITPQTKLVWIETPTNPTLKLA 166
Cdd:PRK06234 87 SGMGAiSSSLWSALKAGDHVVASDTLYGCTFALLNHGLTRYGVEVTFVDTSNLEEVRNALKANTKVVYLETPANPTLKVT 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 167 DIKACAQIVHKH-KDIILVVDNTFMSAYFQRPLALGADICMCSATKYMNGHSDVVMGLVSVNSDDLNE-RLRFLQNSLGA 244
Cdd:PRK06234 167 DIKAISNIAHENnKECLVFVDNTFCTPYIQRPLQLGADVVVHSATKYLNGHGDVIAGFVVGKEEFINQvKLFGIKDMTGS 246
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 245 VPSPFDCYLCCRGLKTLQIRMEKHFRNGMAVARFLESNPRVEKVIYPGLPSHPQHELAKRQCTGCPGMVSFYIKGTLQHA 324
Cdd:PRK06234 247 VIGPFEAFLIIRGMKTLQIRMEKHCKNAMKVAKFLESHPAVEKVYYPGLESFEYYELAKKQMSLPGAMISFELKGGVEEG 326
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1938958469 325 QVFLKNIKLFALAESLGGYESLAELPAIMTHASVPEKDRATLGISDTLIRLSVGLEDEKDLLEDLGQAL 393
Cdd:PRK06234 327 KVVMNNVKLATLAVSLGDAETLIQHPASMTHSPYTAEERKEAGISDGLVRLSVGLEDVDDIIADLKQAL 395
|
|
| O_succ_thio_ly |
TIGR02080 |
O-succinylhomoserine (thiol)-lyase; This family consists of O-succinylhomoserine (thiol)-lyase, ... |
35-396 |
1.56e-127 |
|
O-succinylhomoserine (thiol)-lyase; This family consists of O-succinylhomoserine (thiol)-lyase, one of three different enzymes designated cystathionine gamma-synthase and involved in methionine biosynthesis. In all three cases, sulfur is added by transsulfuration from Cys to yield cystathionine rather than by a sulfhydrylation step that uses H2S directly and bypasses cystathionine. [Amino acid biosynthesis, Aspartate family]
Pssm-ID: 131135 Cd Length: 382 Bit Score: 372.21 E-value: 1.56e-127
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 35 AVVLPISLATTFKQDSPGQSSGFVYSRSGNPTRNCLEKAVAALDGAKHCLTFASGLAATTTI-THLLKAGDEVICMDEVY 113
Cdd:TIGR02080 21 CVVPPIYLSTTYNFTGFNEPRAYDYSRSGNPTRDLLQQALAELEGGAGAVVTNTGMSAIHLVtTALLGPDDLLVAPHDCY 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 114 GGTNRYFRRVASEFGLKISFVDCSKTKLLEAAITPQTKLVWIETPTNPTLKLADIKACAQIVHKhKDIILVVDNTFMSAY 193
Cdd:TIGR02080 101 GGTYRLLNALAKKGCFRVLFVDQGDEQALRAALAQKPKLVLIETPSNPLLRVVDIAKICHLAKA-VGAVVVVDNTFLSPA 179
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 194 FQRPLALGADICMCSATKYMNGHSDVVMGLVSVNSDDLNERLRFLQNSLGAVPSPFDCYLCCRGLKTLQIRMEKHFRNGM 273
Cdd:TIGR02080 180 LQNPLALGADLVLHSCTKYLNGHSDVIAGAVIAKDPQVAEELAWWANNLGVTGGAFDSYLTLRGLRTLVARMRLQQRNAQ 259
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 274 AVARFLESNPRVEKVIYPGLPSHPQHELAKRQCTGCPGMVSFYIKGTLQHAQVFLKNIKLFALAESLGGYESLAELPAIM 353
Cdd:TIGR02080 260 AIVEYLQTQPLVKKIYYPGLPDHPGHEIAARQQKGFGAMLSFELKGGEQTVRRFLGGLSLFTLAESLGGVESLIAHPATM 339
|
330 340 350 360
....*....|....*....|....*....|....*....|...
gi 1938958469 354 THASVPEKDRATLGISDTLIRLSVGLEDEKDLLEDLGQALKAA 396
Cdd:TIGR02080 340 THAAMGPEARAEAGISDTLLRLSVGLEDADDLIADLEQGLRAA 382
|
|
| MET17 |
COG2873 |
O-acetylhomoserine/O-acetylserine sulfhydrylase, pyridoxal phosphate-dependent [Amino acid ... |
12-396 |
5.75e-127 |
|
O-acetylhomoserine/O-acetylserine sulfhydrylase, pyridoxal phosphate-dependent [Amino acid transport and metabolism]; O-acetylhomoserine/O-acetylserine sulfhydrylase, pyridoxal phosphate-dependent is part of the Pathway/BioSystem: Methionine biosynthesis
Pssm-ID: 442120 [Multi-domain] Cd Length: 428 Bit Score: 372.44 E-value: 5.75e-127
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 12 PSFQHFATQAIHVGQEPEQwSSRAVVLPISLATTFKQDSP--------GQSSGFVYSRSGNPTRNCLEKAVAALDGAKHC 83
Cdd:COG2873 3 EKKYGFETLALHAGQEPDP-TTGARAVPIYQTTSYVFDDAehaadlfaLKEPGNIYTRIMNPTTDVLEKRIAALEGGVAA 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 84 LTFASGLAATT-TITHLLKAGDEVICMDEVYGGTNRYFRRVASEFGLKISFVDCSKTKLLEAAITPQTKLVWIETPTNPT 162
Cdd:COG2873 82 LATASGQAAITlAILNLAEAGDHIVASSSLYGGTYNLFAHTLPRLGIEVRFVDPDDPEAFEAAIDPNTKAIFGETIGNPA 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 163 LKLADIKACAQIVHKHkDIILVVDNTFMSAYFQRPLALGADICMCSATKYMNGHSDVVMGLVsVNS-----------DDL 231
Cdd:COG2873 162 LDVLDIEAIAEIAHEH-GVPLIVDNTFATPYLCRPIEHGADIVVHSATKYIGGHGTSIGGVI-VDGgnfdwaangkfPEL 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 232 NE-----------------------RLRFLQNsLGAVPSPFDCYLCCRGLKTLQIRMEKHFRNGMAVARFLESNPRVEKV 288
Cdd:COG2873 240 TEpdpsyhglvyteafgnaafitkaRVQLLRD-LGAALSPFNAFLLLQGLETLSLRMERHVENALKVAEFLEAHPKVAWV 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 289 IYPGLPSHPQHELAKRQCT-GCPGMVSFYIKGTLQHAQVFLKNIKLFALAESLGGYESLAELPAIMTHASVPEKDRATLG 367
Cdd:COG2873 319 NYPGLPSHPYHELAQKYLPkGAGGVLTFGLKGGREAGKKFIDSLKLFSHLANIGDAKSLVIHPASTTHSQLSEEEQAAAG 398
|
410 420
....*....|....*....|....*....
gi 1938958469 368 ISDTLIRLSVGLEDEKDLLEDLGQALKAA 396
Cdd:COG2873 399 VTPDLIRLSVGIEDIDDIIADLDQALAAA 427
|
|
| met_gam_lyase |
TIGR01328 |
methionine gamma-lyase; This model describes a methionine gamma-lyase subset of a family of ... |
15-395 |
7.51e-126 |
|
methionine gamma-lyase; This model describes a methionine gamma-lyase subset of a family of PLP-dependent trans-sulfuration enzymes. The member from the parasite Trichomonas vaginalis is described as catalyzing alpha gamma- and alpha-beta eliminations and gamma-replacement reactions on methionine, cysteine, and some derivatives. Likewise, the enzyme from Pseudomonas degrades cysteine as well as methionine. [Energy metabolism, Amino acids and amines]
Pssm-ID: 130395 [Multi-domain] Cd Length: 391 Bit Score: 368.45 E-value: 7.51e-126
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 15 QHFATQAIHVGQEPEQwSSRAVVLPISLATTFKQDS--------PGQSSGFVYSRSGNPTRNCLEKAVAALDGAKHCLTF 86
Cdd:TIGR01328 2 MTFATRAIHAGYPPKD-QFGALTPPIYQTSTFVFDSceqggnrfAGQESGYIYSRLGNPTVSNLEGRIAFLEGTEAAVAT 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 87 ASGLAA-TTTITHLLKAGDEVICMDEVYGGTNRYFRRVASEFGLKISFVDCSKTKLLEAAITPQTKLVWIETPTNPTLKL 165
Cdd:TIGR01328 81 SSGMGAiAATLLTILKAGDHLISDECLYGCTFALLEHALTKFGIQVDFINMAIPEEVKAHIKDNTKIVYFETPANPTMKL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 166 ADIKACAQIVHKhKDIILVVDNTFMSAYFQRPLALGADICMCSATKYMNGHSDVVMGLVSVNSDDLNE-RLRFLQNSLGA 244
Cdd:TIGR01328 161 IDMERVCRDAHS-QGVKVIVDNTFATPMLTNPVALGVDVVVHSATKYIGGHGDVVAGLICGKAELLQQiRMVGIKDMTGS 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 245 VPSPFDCYLCCRGLKTLQIRMEKHFRNGMAVARFLESNPRVEKVIYPGLPSHPQHELAKRQCTGCPGMVSFYIKGTLQHA 324
Cdd:TIGR01328 240 VISPFDAWLILRGLKTLNIRMKRHSENAMKVAEYLKSHPAVEKVYYPGFEDHPGHDIAAKQMRMGGGMITFELKGGFAGA 319
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1938958469 325 QVFLKNIKLFALAESLGGYESLAELPAIMTHASVPEKDRATLGISDTLIRLSVGLEDEKDLLEDLGQALKA 395
Cdd:TIGR01328 320 KKLLNNLKLIRLAVSLGDAETLIQHPASMTHAVVPKEEREAAGITDGMIRLSVGLEDADDLIADLKQALDA 390
|
|
| PRK08247 |
PRK08247 |
methionine biosynthesis PLP-dependent protein; |
35-396 |
2.45e-124 |
|
methionine biosynthesis PLP-dependent protein;
Pssm-ID: 181320 [Multi-domain] Cd Length: 366 Bit Score: 363.64 E-value: 2.45e-124
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 35 AVVLPISLATTFKQDSPGQSSGFVYSRSGNPTRNCLEKAVAALDGAKHCLTFASGLAATTTITHLLKAGDEVICMDEVYG 114
Cdd:PRK08247 22 TVNPPVYFSTAYRHEGIGESTGFDYSRTGNPTRGVLEQAIADLEGGDQGFACSSGMAAIQLVMSLFRSGDELIVSSDLYG 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 115 GTNRYFRRVASEFGLKISFVDCSKTKLLEAAITPQTKLVWIETPTNPTLKLADIKACAQIVHKHkDIILVVDNTFMSAYF 194
Cdd:PRK08247 102 GTYRLFEEHWKKWNVRFVYVNTASLKAIEQAITPNTKAIFIETPTNPLMQETDIAAIAKIAKKH-GLLLIVDNTFYTPVL 180
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 195 QRPLALGADICMCSATKYMNGHSDVVMGLVSVNSDDLNERLRFLQNSLGAVPSPFDCYLCCRGLKTLQIRMEKHFRNGMA 274
Cdd:PRK08247 181 QRPLEEGADIVIHSATKYLGGHNDVLAGLVVAKGQELCERLAYYQNAAGAVLSPFDSWLLIRGMKTLALRMRQHEENAKA 260
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 275 VARFLESNPRVEKVIYPGlpshpqhelakrqcTGcpGMVSFYIKgtlQHAQV--FLKNIKLFALAESLGGYESLAELPAI 352
Cdd:PRK08247 261 IAAFLNEQPGVTDVLYPG--------------RG--GMLSFRLQ---DEEWVnpFLKSLKLITFAESLGGVESFITYPAT 321
|
330 340 350 360
....*....|....*....|....*....|....*....|....
gi 1938958469 353 MTHASVPEKDRATLGISDTLIRLSVGLEDEKDLLEDLGQALKAA 396
Cdd:PRK08247 322 QTHADIPEEIRIANGVCNRLLRFSVGIENVEDLIADLKQAFKQV 365
|
|
| PRK08064 |
PRK08064 |
cystathionine beta-lyase MetC; |
35-398 |
1.03e-123 |
|
cystathionine beta-lyase MetC;
Pssm-ID: 236146 [Multi-domain] Cd Length: 390 Bit Score: 362.94 E-value: 1.03e-123
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 35 AVVLPISLATTFKQDSPGQSSGFVYSRSGNPTRNCLEKAVAALDGAKHCLTFASGLAATTTITHLLKAGDEVICMDEVYG 114
Cdd:PRK08064 24 AVNVPIYHASTFHQFDFDTFGKYDYSRSGNPTREALEDIIAELEGGTKGFAFASGMAAISTAFLLLSKGDHVLISEDVYG 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 115 GTNRYFRRVASEFGLKISFVDCSKTKLLEAAITPQTKLVWIETPTNPTLKLADIKACAQIVHKHkDIILVVDNTFMSAYF 194
Cdd:PRK08064 104 GTYRMITEVLSRFGIEHTFVDMTNLEEVAQNIKPNTKLFYVETPSNPLLKVTDIRGVVKLAKAI-GCLTFVDNTFLTPLL 182
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 195 QRPLALGADICMCSATKYMNGHSDVVMGLVSVNSDDLNERLRFLQNSLGAVPSPFDCYLCCRGLKTLQIRMEKHFRNGMA 274
Cdd:PRK08064 183 QKPLDLGADVVLHSATKFLAGHSDVLAGLAVVKDEELAQKLYFLQNSFGAVLGVQDCWLVLRGLKTLHVRLEHSSETANK 262
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 275 VARFLESNPRVEKVIYPGLPSHPQHELAKRQCTGCPGMVSFYIkGTLQHAQVFLKNIKLFALAESLGGYESLAELPAIMT 354
Cdd:PRK08064 263 IALYLQEHPKVQNVYYPGLQTHLGFDIQQSQATSAGAVLSFTL-QSEEAVRQFVSHVKLPVFAVSLGAVESILSYPAKMS 341
|
330 340 350 360
....*....|....*....|....*....|....*....|....
gi 1938958469 355 HASVPEKDRATLGISDTLIRLSVGLEDEKDLLEDLGQALKAAHP 398
Cdd:PRK08064 342 HAAMPKEERDERGITDGLLRLSVGLENVDDLIADFEQALSYVEE 385
|
|
| PRK07503 |
PRK07503 |
methionine gamma-lyase; Provisional |
17-397 |
6.96e-123 |
|
methionine gamma-lyase; Provisional
Pssm-ID: 181005 [Multi-domain] Cd Length: 403 Bit Score: 361.43 E-value: 6.96e-123
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 17 FATQAIHVGQEPEQwSSRAVVLPISLATTFKQDS--------PGQSSGFVYSRSGNPTRNCLEKAVAALDGAKHCLTFAS 88
Cdd:PRK07503 10 FSTRAIHHGYDPLD-HGGALVPPVYLTATFAFPTaeygaecfAGEEEGHFYSRISNPTLALLEQRMASLEGGEAAVALAS 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 89 GLAA-TTTITHLLKAGDEVICMDEVYGGTNRYFRRVASEFGLKISFVDCSKTKLLEAAITPQTKLVWIETPTNPTLKLAD 167
Cdd:PRK07503 89 GMGAiTATLWTLLRPGDEVIVDQTLYGCTFAFLHHGLGEFGVTVRHVDLTDPAALKAAISDKTRMVYFETPANPNMRLVD 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 168 IKACAQIVHKHkDIILVVDNTFMSAYFQRPLALGADICMCSATKYMNGHSDVVMGLVSVNSDDLNE-RLRFLQNSLGAVP 246
Cdd:PRK07503 169 IAAVAEIAHGA-GAKVVVDNTYCTPYLQRPLELGADLVVHSATKYLGGHGDITAGLVVGGKALADRiRLEGLKDMTGAVM 247
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 247 SPFDCYLCCRGLKTLQIRMEKHFRNGMAVARFLESNPRVEKVIYPGLPSHPQHELAKRQCTGCPGMVSFYIKGTLQHAQV 326
Cdd:PRK07503 248 SPFDAFLLMRGLKTLALRMDRHCASAQAVAEWLARHPAVELVHYPGLPSFAQHALAQRQMALPGGMIAFELKGGIAAGRR 327
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1938958469 327 FLKNIKLFALAESLGGYESLAELPAIMTHASVPEKDRATLGISDTLIRLSVGLEDEKDLLEDLGQALKAAH 397
Cdd:PRK07503 328 FMNALQLFARAVSLGDAESLAQHPASMTHSTYTPEERAEHGISEGLVRLSVGLEDVADILADLAQALDACA 398
|
|
| PLN02509 |
PLN02509 |
cystathionine beta-lyase |
35-398 |
8.09e-120 |
|
cystathionine beta-lyase
Pssm-ID: 178125 [Multi-domain] Cd Length: 464 Bit Score: 355.88 E-value: 8.09e-120
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 35 AVVLPISLATTFKQDSPGQSSGFVYSRSGNPTRNCLEKAVAALDGAKHCLTFASGLAATTTITHLLKAGDEVICMDEVYG 114
Cdd:PLN02509 103 AMSTPLYQTATFKQPSAIENGPYDYTRSGNPTRDALESLLAKLDKADRAFCFTSGMAALSAVTHLIKNGEEIVAGDDVYG 182
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 115 GTNRYFRRVASEFGLKISFVDCSKTKLLEAAITPQTKLVWIETPTNPTLKLADIKACAQIVHKHKDIILVvDNTFMSAYF 194
Cdd:PLN02509 183 GSDRLLSQVVPRSGVVVKRVNTTNLDEVAAAIGPQTKLVWLESPTNPRQQISDIRKIAEMAHAQGALVLV-DNSIMSPVL 261
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 195 QRPLALGADICMCSATKYMNGHSDVVMGLVSVNSDDLNERLRFLQNSLGAVPSPFDCYLCCRGLKTLQIRMEKHFRNGMA 274
Cdd:PLN02509 262 SRPLELGADIVMHSATKFIAGHSDVMAGVLAVKGEKLAKEVYFLQNSEGSGLAPFDCWLCLRGIKTMALRIEKQQENARK 341
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 275 VARFLESNPRVEKVIYPGLPSHPQHELAKRQCTGCPGMVSFyIKGTLQHAQVFLKNIKLFALAESLGGYESLAELPAIMT 354
Cdd:PLN02509 342 IAMYLSSHPRVKKVYYAGLPDHPGHHLHFSQAKGAGSVFSF-ITGSVALSKHLVETTKYFSIAVSFGSVKSLISMPCFMS 420
|
330 340 350 360
....*....|....*....|....*....|....*....|....
gi 1938958469 355 HASVPEKDRATLGISDTLIRLSVGLEDEKDLLEDLGQALKAAHP 398
Cdd:PLN02509 421 HASIPAEVREARGLTEDLVRISAGIEDVDDLISDLDIAFRTGPL 464
|
|
| PRK06767 |
PRK06767 |
methionine gamma-lyase; Provisional |
15-394 |
9.24e-116 |
|
methionine gamma-lyase; Provisional
Pssm-ID: 180685 [Multi-domain] Cd Length: 386 Bit Score: 342.59 E-value: 9.24e-116
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 15 QHFATQAIHVGQEPEQWSSrAVVLPISLATTFKQDS--------PGQSSGFVYSRSGNPTRNCLEKAVAALDGAKHCLTF 86
Cdd:PRK06767 4 KHMETALIHHGYTSEEHKG-SLTPPLFQTSTFTFETaqqgeasfAGVDPSYIYSRLGNPTVKLFEERMAVLEGGEEALAF 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 87 ASGLAA-TTTITHLLKAGDEVICMDEVYGGTNRYFRRVASEFGLKISFVDCSKTKLLEAAITPQTKLVWIETPTNPTLKL 165
Cdd:PRK06767 83 GSGMAAiSATLIGFLKAGDHIICSNGLYGCTYGFLEVLEEKFMITHSFCDMETEADIENKIRPNTKLIFVETPINPTMKL 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 166 ADIKACAQiVHKHKDIILVVDNTFMSAYFQRPLALGADICMCSATKYMNGHSDVVMGLVSVNSDDLNERLRFLQNSLGAV 245
Cdd:PRK06767 163 IDLKQVIR-VAKRNGLLVIVDNTFCSPYLQRPLELGCDAVVHSATKYIGGHGDVVAGVTICKTRALAEKIRPMRKDIGGI 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 246 PSPFDCYLCCRGLKTLQIRMEKHFRNGMAVARFLESNPRVEKVIYpglpshPQHELAKRQCTGCPGMVSFYIKGTLQHAQ 325
Cdd:PRK06767 242 MAPFDAWLLLRGLKTLAVRMDRHCDNAEKIVSFLKNHDAVEGVWY------PEGELASRQMKRGGGVISFSIKGGKEETQ 315
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1938958469 326 VFLKNIKLFALAESLGGYESLAELPAIMTHASVPEKDRATLGISDTLIRLSVGLEDEKDLLEDLGQALK 394
Cdd:PRK06767 316 AFINDLHFITIAVSLGDTETLIQHPATMTHAAIPAELRQEMGIYDNLIRLSVGLESWEDIVSDLEQALK 384
|
|
| PRK08133 |
PRK08133 |
O-succinylhomoserine sulfhydrylase; Validated |
16-395 |
3.28e-112 |
|
O-succinylhomoserine sulfhydrylase; Validated
Pssm-ID: 181244 [Multi-domain] Cd Length: 390 Bit Score: 333.51 E-value: 3.28e-112
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 16 HFATQAIHVGQE--PEQWSSRAVVLPISL--------ATTFKqdspGQSSGFVYSRSGNPTRNCLEKAVAALDGAKHCLT 85
Cdd:PRK08133 6 GFDTLAVRAGQLrsPFGEHSEALFLTSSFvfesaaeaAARFA----GEEPGNIYSRFTNPTVTMFQERLAALEGAEACVA 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 86 FASGLAA-TTTITHLLKAGDEVICMDEVYGGTNRYFRRVASEFGLKISFVDCSKTKLLEAAITPQTKLVWIETPTNPTLK 164
Cdd:PRK08133 82 TASGMAAiLAVVMALLQAGDHVVSSRSLFGSTVSLFEKIFARFGIETTFVDLTDLDAWRAAVRPNTKLFFLETPSNPLTE 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 165 LADIKACAQIVHKHkDIILVVDNTFMSAYFQRPLALGADICMCSATKYMNGHSDVVMGLVSVNSDDLNERLRFLQnSLGA 244
Cdd:PRK08133 162 LADIAALAEIAHAA-GALLVVDNCFCTPALQQPLKLGADVVIHSATKYLDGQGRVLGGAVVGSKELMEEVFGFLR-TAGP 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 245 VPSPFDCYLCCRGLKTLQIRMEKHFRNGMAVARFLESNPRVEKVIYPGLPSHPQHELAKRQCTGCPGMVSFYIKGTLQHA 324
Cdd:PRK08133 240 TLSPFNAWVFLKGLETLSLRMEAHSANALALAEWLEAHPGVERVFYPGLPSHPQHELAKRQQKGGGAIVSFEVKGGREAA 319
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1938958469 325 QVFLKNIKLFALAESLGGYESLAELPAIMTHASVPEKDRATLGISDTLIRLSVGLEDEKDLLEDLGQALKA 395
Cdd:PRK08133 320 WRVIDATRLISITANLGDTKTTITHPATTTHGRLSPEARAAAGITEGLIRVAVGLEDVADIKADLARGLAA 390
|
|
| PRK08574 |
PRK08574 |
cystathionine gamma-synthase family protein; |
18-395 |
1.36e-111 |
|
cystathionine gamma-synthase family protein;
Pssm-ID: 236298 [Multi-domain] Cd Length: 385 Bit Score: 332.03 E-value: 1.36e-111
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 18 ATQAIHVGQEPEQWssRAVVLPISLATTFKQDSPGQSS--GFV--YSRSGNPTRNCLEKAVAALDGAKHCLTFASGLAAT 93
Cdd:PRK08574 4 GTDAVRGYRGSDPY--GSLQPPIYLTALFRQEGEAYPSdrGFDlkYSREENPTLRPLEEALAKLEGGVDALAFNSGMAAI 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 94 TTI-THLLKAGDEVICMDEVYGGTNRYFRRVaSEFGLKISFVDCSKTKLLEAAITPQTKLVWIETPTNPTLKLAD----I 168
Cdd:PRK08574 82 STLfFSLLKAGDRVVLPMEAYGTTLRLLKSL-EKFGVKVVLAYPSTEDIIEAIKEGRTKLVFIETMTNPTLKVIDvpevA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 169 KACaqivhKHKDIILVVDNTFMSAYFQRPLALGADICMCSATKYMNGHSDVVMGLVSVNSDDLNERLRFLQNSLGAVPSP 248
Cdd:PRK08574 161 KAA-----KELGAILVVDNTFATPLLYRPLRHGADFVVHSLTKYIAGHNDVVGGVAVAWSGEFLEELWEWRRRLGTIMQP 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 249 FDCYLCCRGLKTLQIRMEKHFRNGMAVARFLESNPRVEKVIYPGLPSHPQHELAKRqCTGCP---GMVSFYIKGTLQHAQ 325
Cdd:PRK08574 236 FEAYLVLRGLKTLEVRFERQCRNAMAIAEFLSEHPKVAEVYYPGLPSDPYHGVAKR-LFGKDlygGVVSFRVKGGRDAVL 314
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 326 VFLKNIKLFALAESLGGYESLAELPAIMTHASVPEKDRATLGISDTLIRLSVGLEDEKDLLEDLGQALKA 395
Cdd:PRK08574 315 KFLRSLKLIKPSPSLGGVESLATYPVKSAASPIPEEDRKALGITEDLVRLSVGLEDVEDLIEDLDQALGS 384
|
|
| PRK08249 |
PRK08249 |
cystathionine gamma-synthase family protein; |
16-396 |
4.70e-108 |
|
cystathionine gamma-synthase family protein;
Pssm-ID: 236202 [Multi-domain] Cd Length: 398 Bit Score: 323.23 E-value: 4.70e-108
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 16 HFATQAIHVGqEPEQWSSRAVVLPISLATTFKQD--------SPGQSSGFVYSRSGNPTRNCLEKAVAALDGAKHCLTFA 87
Cdd:PRK08249 8 GVGTKAVWAG-EKEYLPYGATQVPVVLSVAYGYDdidewydvALGKKPGHIYSRNTNPTVQAFEEKVRILEGAEAATAFS 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 88 SGLAA-TTTITHLLKAGDEVICMDEVYGGTNRYFRRVASEFGLKISFVDCSKTKLLEAAITPQTKLVWIETPTNPTLKLA 166
Cdd:PRK08249 87 TGMAAiSNTLYTFLKPGDRVVSIKDTYGGTNKIFTEFLPRMGVDVTLCETGDHEQIEAEIAKGCDLLYLETPTNPTLKIV 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 167 DIKACAQIVHKHKDIIlVVDNTFMSAYFQRPLALGADICMCSATKYMNGHSDVvMGLVSVNSDDLNERLRFLQNSLGAVP 246
Cdd:PRK08249 167 DIERLAAAAKKVGALV-VVDNTFATPINQNPLALGADLVIHSATKFLSGHADA-LGGVVCGSKELMEQVYHYREINGATM 244
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 247 SPFDCYLCCRGLKTLQIRMEKHFRNGMAVARFLESNPRVEKVIYPGLPSHPQHELAKRQCTGCPGMVSFYIKGTLQHAQV 326
Cdd:PRK08249 245 DPMSAYLILRGMKTLKLRVRQQQESAMALAKYLQTHPKVEAVYYPGLETHPNHEIAKAQMRGFGGILSFVLKGGMDTVKR 324
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 327 FLKNIKLFALAESLGGYESLAELPAIMTHASVPEKDRATLGISDTLIRLSVGLEDEKDLLEDLGQALKAA 396
Cdd:PRK08249 325 LLPKLRYAHRAANLGAVETIYGPARTTSHVENTLEERAALGIPEGLVRISVGIEDTEDLIADLEQAFAHL 394
|
|
| OAH_OAS_sulfhy |
TIGR01326 |
OAH/OAS sulfhydrylase; This model describes a distinct clade of the Cys/Met metabolism ... |
16-394 |
3.35e-107 |
|
OAH/OAS sulfhydrylase; This model describes a distinct clade of the Cys/Met metabolism pyridoxal phosphate-dependent enzyme superfamily. Members include examples of OAH/OAS sulfhydrylase, an enzyme with activity both as O-acetylhomoserine (OAH) sulfhydrylase (EC 2.5.1.49) and O-acetylserine (OAS) sulphydrylase (EC 2.5.1.47). An alternate name for OAH sulfhydrylase is homocysteine synthase. This model is designated subfamily because it may or may not have both activities. [Amino acid biosynthesis, Aspartate family, Amino acid biosynthesis, Serine family]
Pssm-ID: 273555 [Multi-domain] Cd Length: 418 Bit Score: 321.62 E-value: 3.35e-107
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 16 HFATQAIHVGQEPE-QWSSRAVvlPISLATTFKQDSPGQSS--------GFVYSRSGNPTRNCLEKAVAALDGAKHCLTF 86
Cdd:TIGR01326 1 HFETLQLHAGQEPDpTTGSRAV--PIYQTTSYVFDSTEHAAalfglqepGNIYSRLMNPTTDVLEQRIAALEGGVAALAV 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 87 ASGLAATT-TITHLLKAGDEVICMDEVYGGTNRYFRRVASEFGLKISFVDCSKTKLLEAAITPQTKLVWIETPTNPTLKL 165
Cdd:TIGR01326 79 ASGQAAITyAILNLAGAGDNIVSSSYLYGGTYNLFSHTLKRLGIEVRFVDPDDPESLEKAIDENTKAVFAETIGNPQINV 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 166 ADIKACAQIVHKHKdIILVVDNTFMSAYFQRPLALGADICMCSATKYMNGHSdVVMGLVSVNSDDL---NER-------- 234
Cdd:TIGR01326 159 LDIEAIAEVAHRHG-IPLIVDNTFATPYLCRPIKHGADIVVHSATKYIGGHG-TAIGGVIVDGGKFdwnNGRfplfttpd 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 235 -----LRF----------------LQNSLGAVPSPFDCYLCCRGLKTLQIRMEKHFRNGMAVARFLESNPRVEKVIYPGL 293
Cdd:TIGR01326 237 psyhgLVFtetlgnpafilkarvqLLRDLGAALSPFNAFLLLQGLETLSLRMERHVENALKVAEFLESHPDVAWVNYPGL 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 294 PSHPQHELAKRQCTGCPGMV-SFYIKGTLQHAQVFLKNIKLFALAESLGGYESLAELPAIMTHASVPEKDRATLGISDTL 372
Cdd:TIGR01326 317 ASHPHHALAKKYLPKGFGAVlSFEIKGGREAGKKFIDALKLASHLANVGDAKSLVIHPASTTHSQLSEEEQLKAGVTPGL 396
|
410 420
....*....|....*....|..
gi 1938958469 373 IRLSVGLEDEKDLLEDLGQALK 394
Cdd:TIGR01326 397 IRLSVGIENIDDIIADLEQALE 418
|
|
| PRK08776 |
PRK08776 |
O-succinylhomoserine (thiol)-lyase; |
16-396 |
3.66e-106 |
|
O-succinylhomoserine (thiol)-lyase;
Pssm-ID: 181554 [Multi-domain] Cd Length: 405 Bit Score: 318.86 E-value: 3.66e-106
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 16 HFATQAIHVGQEPEQwSSRAVVLPISLATTFKQDSPGQSSGFVYSRSGNPTRNCLEKAVAALDGAKHCLTFASGLAATTT 95
Cdd:PRK08776 12 SAATAAVRAGIDRDT-AYGAVTPPIVLSSNFSFDGFGNKRQYDYTRSGNPTRDLLGEALAELEGGAGGVITATGMGAINL 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 96 ITH-LLKAGDEVICMDEVYGGTNRYFRRVASEFGLKISFVDCSKTKLLEAAITPQTKLVWIETPTNPTLKLADIKACAQI 174
Cdd:PRK08776 91 VLNaLLQPGDTLVVPHDAYGGSWRLFNALAKKGHFALITADLTDPRSLADALAQSPKLVLIETPSNPLLRITDLRFVIEA 170
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 175 VHKhKDIILVVDNTFMSAYFQRPLALGADICMCSATKYMNGHSDVVMGLVSVNSDDLNERLRFLQNSLGAVPSPFDCYLC 254
Cdd:PRK08776 171 AHK-VGALTVVDNTFLSPALQKPLEFGADLVLHSTTKYINGHSDVVGGAVVARDAELHQQLVWWANALGLTGSPFDAFLT 249
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 255 CRGLKTLQIRMEKHFRNGMAVARFLESNPRVEKVIYPGLPSHPQHELAKRQCTGCPGMVSFYIKGTLQHAQVFLKNIKLF 334
Cdd:PRK08776 250 LRGLRTLDARLRVHQENADAIAALLDGHAAVNQVYYPGLASHPGHALAARQQKGFGAMLSFELEGGEAAVRAFVDGLRYF 329
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1938958469 335 ALAESLGGYESLAELPAIMTHASVPEKDRATLGISDTLIRLSVGLEDEKDLLEDLGQALKAA 396
Cdd:PRK08776 330 TLAESLGGVESLIAHPASMTHAAMTAEARAAAGISDGLLRLSVGIESAEDLLIDLRAGLARA 391
|
|
| PRK08861 |
PRK08861 |
O-succinylhomoserine (thiol)-lyase; |
18-396 |
4.09e-105 |
|
O-succinylhomoserine (thiol)-lyase;
Pssm-ID: 181567 [Multi-domain] Cd Length: 388 Bit Score: 315.30 E-value: 4.09e-105
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 18 ATQAIHVGQEPEQwSSRAVVLPISLATTFKQDSPGQSSGFVYSRSGNPTRNCLEKAVAALDGAKHCLTFASGLAATTT-I 96
Cdd:PRK08861 7 ATIAVRTGIESDS-QYHAVVPPIYLSTNYGFPAFGEVPKYDYTRSGNPNRGLLEQTLSELESGKGAVVTNCGTSALNLwV 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 97 THLLKAGDEVICMDEVYGGTNRYFRRVASEFGLKISFVDCSKTKLLEAAITPQTKLVWIETPTNPTLKLADIkacAQIVH 176
Cdd:PRK08861 86 SALLGPDDLIVAPHDCYGGTYRLFNTRANKGDFKVQFVDQSDAAALDAALAKKPKLILLETPSNPLVRVVDI---AELCQ 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 177 KHKDI--ILVVDNTFMSAYFQRPLALGADICMCSATKYMNGHSDVVMGLVSVNSDDLNERLRFLQNSLGAVPSPFDCYLC 254
Cdd:PRK08861 163 KAKAVgaLVAVDNTFLTPVLQKPLELGADFVIHSTTKYINGHSDVIGGVLITKTKEHAEELAWWGNCIGATGTPFDSYMT 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 255 CRGLKTLQIRMEKHFRNGMAVARFLESNPRVEKVIYPGLPSHPQHELAKRQCTGCPGMVSFYIKGTLQHAQVFLKNIKLF 334
Cdd:PRK08861 243 LRGIRTLGARMRVHEESAQQILAYLQTQSLVGTIYHPSLPEHPGHEIAKKQQSGFGSMLSFEFAGSFEQLKVFVKALALF 322
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1938958469 335 ALAESLGGYESLAELPAIMTHASVPEKDRATLGISDTLIRLSVGLEDEKDLLEDLGQALKAA 396
Cdd:PRK08861 323 SLAESLGGVESLICHPASMTHRAMGEEALAEAGVSQQLLRLSVGLEDAQDLIADLDQAFAKA 384
|
|
| PRK06434 |
PRK06434 |
cystathionine gamma-lyase; Validated |
14-395 |
2.14e-103 |
|
cystathionine gamma-lyase; Validated
Pssm-ID: 102374 [Multi-domain] Cd Length: 384 Bit Score: 311.07 E-value: 2.14e-103
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 14 FQHFATQAIHVGQ--EPEQWSsraVVLPISLATTF------KQDSPGQSSG--FVYSRSGNPTRNCLEKAVAALDGAKHC 83
Cdd:PRK06434 6 LNGFNTRAVQSGElrDPRFGN---VTTPIFETSTFvypnseKEAYMDSTRGmpYIYTRWGNPTVQAFEEKYAVLENAEHA 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 84 LTFASGLAA-TTTITHLLKAGDEVICMDEVYGGTNRYFRRVASEFGLKISFVDCSKTKLLEaaITPQT-KLVWIETPTNP 161
Cdd:PRK06434 83 LSFSSGMGAiTSAILSLIKKGKRILSISDLYGQTFYFFNKVLKTLGIHVDYIDTDRLNSLD--FDPSNyDLIYAESITNP 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 162 TLKLADIKACAQIVHKHKdiiLVVDNTFMSAYFQRPLALGADICMCSATKYMNGHSDVVMGLVSVNSDDLNERLRFLQNS 241
Cdd:PRK06434 161 TLKVPDIKNVSSFCHEND---VIVDATFASPYNQNPLDLGADVVIHSATKYISGHSDVVMGVAGTNNKSIFNNLVERRKT 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 242 LGAVPSPFDCYLCCRGLKTLQIRMEKHFRNGMAVARFLESNPRVEKVIYPGLpshpqhELAKRQCTGCPGMVSFYIKgTL 321
Cdd:PRK06434 238 LGSNPDPIQAYLALRGLKTLGLRMEKHNKNGMELARFLRDSKKISNVYYPDT------EIGKKVLRGFGGMLSFELR-SM 310
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1938958469 322 QHAQVFLKNIKLFALAESLGGYESLAELPAIMTHASVPEKDRATLGISDTLIRLSVGLEDEKDLLEDLGQALKA 395
Cdd:PRK06434 311 EDVHKFIRNLEIPMVAASLGGVESLITLPVETSHSSLSPEERERLGISDNLVRFSIGIEDIDDLIKDIENALSK 384
|
|
| PRK08045 |
PRK08045 |
cystathionine gamma-synthase; Provisional |
18-396 |
1.31e-102 |
|
cystathionine gamma-synthase; Provisional
Pssm-ID: 169194 [Multi-domain] Cd Length: 386 Bit Score: 309.13 E-value: 1.31e-102
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 18 ATQAIHVG-QEPEQWSsrAVVLPISLATTFKQDSPGQSSGFVYSRSGNPTRNCLEKAVAALDGAKHCLTFASGLAATTTI 96
Cdd:PRK08045 6 ATIAVRSGlNDDEQYG--CVVPPIHLSSTYNFTGFNEPRAHDYSRRGNPTRDVVQRALAELEGGAGAVLTNTGMSAIHLV 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 97 -THLLKAGDEVICMDEVYGGTNRYFRRVASEFGLKISFVDCSKTKLLEAAITPQTKLVWIETPTNPTLKLADIKACAQIV 175
Cdd:PRK08045 84 tTVFLKPGDLLVAPHDCYGGSYRLFDSLAKRGCYRVLFVDQGDEQALRAALAEKPKLVLVESPSNPLLRVVDIAKICHLA 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 176 HKhKDIILVVDNTFMSAYFQRPLALGADICMCSATKYMNGHSDVVMGLVSVNSDDLNERLRFLQNSLGAVPSPFDCYLCC 255
Cdd:PRK08045 164 RE-AGAVSVVDNTFLSPALQNPLALGADLVLHSCTKYLNGHSDVVAGVVIAKDPDVVTELAWWANNIGVTGGAFDSYLLL 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 256 RGLKTLQIRMEKHFRNGMAVARFLESNPRVEKVIYPGLPSHPQHELAKRQCTGCPGMVSFYIKGTLQHAQVFLKNIKLFA 335
Cdd:PRK08045 243 RGLRTLVPRMELAQRNAQAIVKYLQTQPLVKKLYHPSLPENQGHEIAARQQKGFGAMLSFELDGDEQTLRRFLGGLSLFT 322
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1938958469 336 LAESLGGYESLAELPAIMTHASVPEKDRATLGISDTLIRLSVGLEDEKDLLEDLGQALKAA 396
Cdd:PRK08045 323 LAESLGGVESLISHAATMTHAGMAPEARAAAGISETLLRISTGIEDGEDLIADLENGFRAA 383
|
|
| O_suc_HS_sulf |
TIGR01325 |
O-succinylhomoserine sulfhydrylase; This model describes O-succinylhomoserine sulfhydrylase, ... |
18-393 |
3.18e-102 |
|
O-succinylhomoserine sulfhydrylase; This model describes O-succinylhomoserine sulfhydrylase, one of several related pyridoxal phosphate-dependent enzymes of cysteine and methionine metabolism. This enzyme is part of an alternative pathway of homocysteine biosynthesis, a step in methionine biosynthesis. [Amino acid biosynthesis, Aspartate family]
Pssm-ID: 188131 Cd Length: 381 Bit Score: 307.93 E-value: 3.18e-102
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 18 ATQAIHVGQEPEQWSSRAVVLpiSLATTFKQDS--------PGQSSGFVYSRSGNPTRNCLEKAVAALDGAKHCLTFASG 89
Cdd:TIGR01325 1 ATLAVRGGMLRSGFEETAEAL--YLTSGYVYDSaavaakrfAGELPGFVYSRYGNPTVSVFEERLALLEGAEAAVATASG 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 90 LAAT-TTITHLLKAGDEVICMDEVYGGTNRYFRRVASEFGLKISFVDCSKTKLLEAAITPQTKLVWIETPTNPTLKLADI 168
Cdd:TIGR01325 79 MAAIfAALMALLGAGDHVVASRSLFGSCFVVCSEILPRFGVQTVFVDGTDLSAWEAALKPNTKAVFVETPSNPLQELVDI 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 169 KACAQIVHKhKDIILVVDNTFMSAYFQRPLALGADICMCSATKYMNGHSDVVMGLVSVNSDDLNERLRFLQNSLGAVPSP 248
Cdd:TIGR01325 159 AAVAELAHA-AGAKVVVDNVFATPLLQQPLKLGADVVVYSATKHIDGQGRVLGGAILGSEEYMDEPVQKLLRHTGPAMSP 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 249 FDCYLCCRGLKTLQIRMEKHFRNGMAVARFLESNPRVEKVIYPGLPSHPQHELAKRQCTGCPGMVSFYIKGTlQHAQVFL 328
Cdd:TIGR01325 238 FNAWVLLKGLETLAIRVQHQNASALAIAEWLNGHPSVQWVYYPGLPSHPQHELAKRQMSGGGTVVTFDLDCR-QAAFKVL 316
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1938958469 329 KNIKLFALAESLGGYESLAELPAIMTHASVPEKDRATLGISDTLIRLSVGLEDEKDLLEDLGQAL 393
Cdd:TIGR01325 317 DAMRLVDISNNLGDAKSTITHPATTTHRRMGPEERAAAGIGDGLVRLSVGLEDVDDLIADIDRAL 381
|
|
| PRK07269 |
PRK07269 |
cystathionine gamma-synthase; Reviewed |
16-395 |
9.76e-101 |
|
cystathionine gamma-synthase; Reviewed
Pssm-ID: 235983 Cd Length: 364 Bit Score: 303.28 E-value: 9.76e-101
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 16 HFATQAIHVGQEPEQwSSRAVVLPISLATTFKQDSPGQSSGFVYSRSGNPTRNCLEKAVAALDGAKHCLTFASGLAATTT 95
Cdd:PRK07269 6 HINTILAQAGIKSDE-ATGALVTPLHFSTTYQHPEFGQSTGFDYTRTKNPTRAKLEETLAAIESADYALATSSGMSAIVL 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 96 ITHLLKAGDEVICMDEVYGGTNRYFRRVASEFglKISFVDCSKTKLLEAAITPQTKLVWIETPTNPTLKLADIKACAQIV 175
Cdd:PRK07269 85 AFSVFPVGSKVVAVRDLYGGSFRWFNQQEKEG--RFHFTYANTEEELIAAIEEDTDIVYIETPTNPLMVEFDIEKVAKLA 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 176 HKhKDIILVVDNTFMSAYFQRPLALGADICMCSATKYMNGHSDVVMGLVSVNSDDLNERLRFLQNSLGAVPSPFDCYLCC 255
Cdd:PRK07269 163 HA-KGAKVIVDNTFYSPIYQRPIELGADIVLHSATKYLSGHNDVLAGVVVTNDLELYEKLFYNLNTTGAVLSPFDSYLLM 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 256 RGLKTLQIRMEKHFRNGMAVARFLESNPRVEKVIYPGLpshpqhelakrqctgcPGMVSFYI--KGTLQHaqvFLKNIKL 333
Cdd:PRK07269 242 RGLKTLSLRMERSTANAQEVVAFLKKSPAVKEVLYTGK----------------GGMISFKVadETRIPH---ILNSLKV 302
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1938958469 334 FALAESLGGYESLAELPAIMTHASVPEKDRATLGISDTLIRLSVGLEDEKDLLEDLGQALKA 395
Cdd:PRK07269 303 FTFAESLGGVESLITYPTTQTHADIPAEVRHSYGLTDDLLRLSIGIEDARDLIADLKQALEG 364
|
|
| PRK07049 |
PRK07049 |
cystathionine gamma-synthase family protein; |
16-396 |
5.81e-96 |
|
cystathionine gamma-synthase family protein;
Pssm-ID: 180809 [Multi-domain] Cd Length: 427 Bit Score: 293.50 E-value: 5.81e-96
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 16 HFATQAIHVGQEPEqWSSRAVVLPISLATTF------------------KQDSPGQSSGFVYSRSGNPTRNCLEKAVAAL 77
Cdd:PRK07049 17 HPETQMLNYGYDPE-LSEGAVKPPVFLTSTFvfrsaedgrdffdyvsgrKEPPAGEGAGLVYSRFNHPNSEIVEDRLAVY 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 78 DGAKHCLTFASGLAA-TTTITHLLKAGDEVICMDEVYGGTNRYFRRVASEFGLK-ISFVDCSKTKLLEAAITP-----QT 150
Cdd:PRK07049 96 EGAESAALFSSGMSAiATTLLAFVRPGDVILHSQPLYGGTETLLAKTFRNFGVGaVGFADGLSEAAIGAAAEAaaakgRV 175
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 151 KLVWIETPTNPTLKLADIKACAQIV------HKHKDIIlVVDNTFMSAYFQRPLALGADICMCSATKYMNGHSDVVMGLV 224
Cdd:PRK07049 176 SLILIETPANPTNSLVDVAAVRRVAdaiearQGHRPII-ACDNTLLGPVFQKPLEHGADLSVYSLTKYVGGHSDLVAGAV 254
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 225 sVNSDDLNERLRFLQNSLGAVPSPFDCYLCCRGLKTLQIRMEKHFRNGMAVARFLESNPRVEKVIYPGL--PSHPQHELA 302
Cdd:PRK07049 255 -LGRKALIRQVRALRSAIGTQLDPHSCWMLGRSLETLVLRMERANRNARAVAEFLRDHPKVEKLHYLPFldPDSAYGAVY 333
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 303 KRQCTGCPGMVSFYIKGTLQHAQVFLKNIKLFALAESLGGYESLAELPAIMTHASVPEKDRATLGISDTLIRLSVGLEDE 382
Cdd:PRK07049 334 KRQCTGAGSTFSFDIKGGQAAAFRFLNALQIFKLAVSLGGTESLASHPASMTHSGVPADVRERIGVLESTIRLSIGIEHP 413
|
410
....*....|....
gi 1938958469 383 KDLLEDLGQALKAA 396
Cdd:PRK07049 414 DDLIADLAQALDAA 427
|
|
| PRK06460 |
PRK06460 |
hypothetical protein; Provisional |
18-393 |
6.10e-92 |
|
hypothetical protein; Provisional
Pssm-ID: 235807 [Multi-domain] Cd Length: 376 Bit Score: 281.33 E-value: 6.10e-92
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 18 ATQAIHVGQEPEqwsSRAVVLPISLATTFkqDSPGqSSGFVYSRSGNPTRNCLEKAVAALDGAKHCLTFASGLAA-TTTI 96
Cdd:PRK06460 4 ATRTVREDIDEA---TGAITTPIYQTTAY--HYPE-GEKYRYSREANPTVLELTKKIVELENAEMGVAFSSGMGAiSTTA 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 97 THLLKAGDEVICMDEVYGGTNRYFRRVASEFGLKISFVDCSKTKLLEAAITPQTKLVWIETPTNPTLKLADIKACAQIVh 176
Cdd:PRK06460 78 LALLKPGNSVLVHRDMFGRSYRFFTDYLKNWGVNVDASNPGSDNIIEKAKSKRYDVVFVENITNPLLRVVDITELSKVC- 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 177 KHKDIILVVDNTFMSAYFQRPLALGADICMCSATKYMNGHSDVVMGLVSVNSDDLNeRLRFLQNSLGAVPSPFDCYLCCR 256
Cdd:PRK06460 157 KENGSILIVDATFSTPINQKPLELGADIVVHSASKFLAGHNDVIAGLAAGYGKLLN-VIDQMRRTLGTSLDPHAAYLTLR 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 257 GLKTLQIRMEKHFRNGMAVARFLESNPRVEKVIYPGLPSHPQHELAKRQCTGCPGMVSFYIKGTLQHAQVFLKNIKLFAL 336
Cdd:PRK06460 236 GIKTLKIRMDVINRNAEQIAEFLEGHPKVVKVYYPGLKSHVDYEIARRVLKGFGGVLSFEVNGGQESALKVMKSLKLIIP 315
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*..
gi 1938958469 337 AESLGGYESLAELPAIMTHASVPEKDRATLGISDTLIRLSVGLEDEKDLLEDLGQAL 393
Cdd:PRK06460 316 AQTLGGVNSVISHPATMSHRTLSLEERKIVGITDSLLRLSVGIEDVNDLIEDLDRAL 372
|
|
| PRK08248 |
PRK08248 |
homocysteine synthase; |
19-396 |
3.59e-91 |
|
homocysteine synthase;
Pssm-ID: 236201 [Multi-domain] Cd Length: 431 Bit Score: 281.35 E-value: 3.59e-91
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 19 TQAIHVGQEPEQWS-SRAVVLPISLATTFKQDSPG------QSSGFVYSRSGNPTRNCLEKAVAALDGAKHCLTFASGLA 91
Cdd:PRK08248 11 TLAIHAGQEIDPTTgSRAVPIYQTTSYGFRDSEHAanlfslKEFGNIYTRIMNPTTDVFEKRIAALEGGIGALAVSSGQA 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 92 ATT-TITHLLKAGDEVICMDEVYGGTNRYFRRVASEFGLKISFVDCSKTKLLEAAITPQTKLVWIETPTNPTLKLADIKA 170
Cdd:PRK08248 91 AITySILNIASAGDEIVSSSSLYGGTYNLFAHTLPKLGITVKFVDPSDPENFEAAITDKTKALFAETIGNPKGDVLDIEA 170
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 171 CAQIVHKHkDIILVVDNTFMSAYFQRPLALGADICMCSATKYMNGHSDVVMGLVS------------------------- 225
Cdd:PRK08248 171 VAAIAHEH-GIPLIVDNTFASPYLLRPIEHGADIVVHSATKFIGGHGTSIGGVIVdsgkfdwkgsgkfpgltepdpsyhg 249
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 226 -VNSDDLNE-------RLRFLQNsLGAVPSPFDCYLCCRGLKTLQIRMEKHFRNGMAVARFLESNPRVEKVIYPGLPSHP 297
Cdd:PRK08248 250 lVYTDAVGEaayitkaRVQLLRD-LGAALSPFNSFLLLQGLETLHLRMERHSENALAVAKFLEEHEAVEWVSYPGLPSHP 328
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 298 QHELAKRQC-TGCPGMVSFYIKGTLQHAQVFLKNIKLFALAESLGGYESLAELPAIMTHASVPEKDRATLGISDTLIRLS 376
Cdd:PRK08248 329 SYELAKKYLpKGQGAILTFGIKGGVEAGKKLIDSVKLFSHLANVGDSKSLIIHPASTTHQQLSEEEQLAAGVTPGLVRLS 408
|
410 420
....*....|....*....|
gi 1938958469 377 VGLEDEKDLLEDLGQALKAA 396
Cdd:PRK08248 409 VGTEAIDDILDDLRQAIRQS 428
|
|
| PRK07582 |
PRK07582 |
cystathionine gamma-lyase; Validated |
18-396 |
5.64e-89 |
|
cystathionine gamma-lyase; Validated
Pssm-ID: 236061 Cd Length: 366 Bit Score: 273.41 E-value: 5.64e-89
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 18 ATQAIHVGQePEQWSSRAVVLPISLATTFKQDSPGQSSGFVYSRSGNPTRNCLEKAVAALDGAkHCLTFASGLAA-TTTI 96
Cdd:PRK07582 5 GTRSVHAGG-PEAVPGEPVLPGPVFAAPYHLSPGEPTGPDTYGRASNPTWRALEAALGELEGA-EALVFPSGMAAiTAVL 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 97 THLLKAGDEVICMDEVYGGTNRYFRRVASEFGLKISFVDCSKtkLLEAAITPqTKLVWIETPTNPTLKLADIKACAQIVH 176
Cdd:PRK07582 83 RALLRPGDTVVVPADGYYQVRALAREYLAPLGVTVREAPTAG--MAEAALAG-ADLVLAETPSNPGLDVCDLAALAAAAH 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 177 KHKdIILVVDNTFMSAYFQRPLALGADICMCSATKYMNGHSDVVMGLVSVNSDDLNERLRFLQNSLGAVPSPFDCYLCCR 256
Cdd:PRK07582 160 AAG-ALLVVDNTTATPLGQRPLELGADLVVASDTKALTGHSDLLLGYVAGRDPELMAAVERWRLLAGAIPGPFEAWLAHR 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 257 GLKTLQIRMEKHFRNGMAVARFLESNPRVEKVIYPGLPSHPQHELAKRQCTGCPGMVSFYIkGTLQHAQVFLKNIKLFAL 336
Cdd:PRK07582 239 SLGTLGLRFARQCANALAVAELLAGHPAVRGVRYPGLPGDPAHEVAARQMRRFGGLVSFEL-ADAAAAERFVAASRLVVA 317
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1938958469 337 AESLGGYESLAElpaimthasvpekDRATLG--ISDTLIRLSVGLEDEKDLLEDLGQALKAA 396
Cdd:PRK07582 318 ATSFGGVHTSAD-------------RRARWGdaVPEGFVRLSCGIEDTDDLVADLERALDAL 366
|
|
| PRK07504 |
PRK07504 |
O-succinylhomoserine sulfhydrylase; Reviewed |
12-396 |
7.04e-89 |
|
O-succinylhomoserine sulfhydrylase; Reviewed
Pssm-ID: 168979 [Multi-domain] Cd Length: 398 Bit Score: 274.32 E-value: 7.04e-89
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 12 PSFQHF--ATQAIHVGQEPEQW--SSRAvvlpISLATTFKQDSP--------GQSSGFVYSRSGNPTRNCLEKAVAALDG 79
Cdd:PRK07504 4 EMARKWrpATRLVHSGTLRSQFgeTSEA----LFLTQGFVYDTAeaaearfkGEDPGFIYSRYSNPTVDMFEKRMCALEG 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 80 AKHCLTFASGLAA-TTTITHLLKAGDEVICMDEVYGGTNRYFRRVASEFGLKISFVDCSKTKLLEAAITPQTKLVWIETP 158
Cdd:PRK07504 80 AEDARATASGMAAvTAAILCQVKAGDHVVAARALFGSCRYVVETLLPRYGIESTLVDGLDLDNWEKAVRPNTKVFFLESP 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 159 TNPTLKLADIKACAQIVHKHkDIILVVDNTFMSAYFQRPLALGADICMCSATKYMNGHSDVVMGLVSVNSDDLNERLRFL 238
Cdd:PRK07504 160 TNPTLEVIDIAAVAKIANQA-GAKLVVDNVFATPLFQKPLELGAHIVVYSATKHIDGQGRCLGGVVLSDKAWIEEHLQDY 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 239 QNSLGAVPSPFDCYLCCRGLKTLQIRMEKHFRNGMAVARFLESNPRVEKVIYPGLPSHPQHELAKRQCTGCPGMVSFYIK 318
Cdd:PRK07504 239 FRHTGPSLSPFNAWTLLKGLETLPVRVRQQTESAAAIADFLAGHPKVARVIYPGRADHPQADIIAKQMTGGSTLVAFELK 318
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1938958469 319 GTLQHAQVFLKNIKLFALAESLGGYESLAELPAIMTHASVPEKDRATLGISDTLIRLSVGLEDEKDLLEDLGQALKAA 396
Cdd:PRK07504 319 GGKEAAFRFLNALKIVRISNNLGDAKSLITHPATTTHKNLSPEARAELGISEGFLRLSAGLEDTDDLIEDLAAALKKV 396
|
|
| PRK08134 |
PRK08134 |
O-acetylhomoserine aminocarboxypropyltransferase; Validated |
12-396 |
3.42e-88 |
|
O-acetylhomoserine aminocarboxypropyltransferase; Validated
Pssm-ID: 236159 Cd Length: 433 Bit Score: 273.54 E-value: 3.42e-88
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 12 PSFQHFATQAIHVGQEPEQWS-SRAVvlPISLATTFKQDSPGQSS--------GFVYSRSGNPTRNCLEKAVAALDGAKH 82
Cdd:PRK08134 4 MSPPGFDTLALHAGAAPDPATgARAV--PIHLTTSFVFRDSDHAAalfnleraGHVYSRISNPTVAVLEERVAALEGGVG 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 83 CLTFASGLAA-TTTITHLLKAGDEVICMDEVYGGTNRYFRRVASEFGLKISFVDCSKTKLLEAAITPQTKLVWIETPTNP 161
Cdd:PRK08134 82 AIATASGQAAlHLAIATLMGAGSHIVASSALYGGSHNLLHYTLRRFGIETTFVKPGDIDGWRAAIRPNTRLLFGETLGNP 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 162 TLKLADIKACAQIVHKHKdIILVVDNTFMSAYFQRPLALGADICMCSATKYMNGHSDVVMGLV----------------- 224
Cdd:PRK08134 162 GLEVLDIPTVAAIAHEAG-VPLLVDSTFTTPYLLRPFEHGADLVYHSATKFLGGHGTAIGGVLvdggrfdweasgkfpel 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 225 ----------------SVNSDDLNERLRFLQNsLGAVPSPFDCYLCCRGLKTLQIRMEKHFRNGMAVARFLESNPRVEKV 288
Cdd:PRK08134 241 tepyagfhgmvfaeesTVAAFLLRARREGLRD-FGACLSPMNAWQLLQGIETLPLRMERHVANTRKVVAFLASHPAVARV 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 289 IYPGLPSHPQHELAKRQC-TGCPGMVSFYIKGTLQHAQVFLKNIKLFALAESLGGYESLAELPAIMTHASVPEKDRATLG 367
Cdd:PRK08134 320 AHPELESHPDHALAKRLLpRGAGSVFSFDLKGGRAAGRKFIESLKLFSHLANVGDARSLVIHPASTTHFRMDAAALAAAG 399
|
410 420
....*....|....*....|....*....
gi 1938958469 368 ISDTLIRLSVGLEDEKDLLEDLGQALKAA 396
Cdd:PRK08134 400 IGEGTIRLSIGLEDADDLIDDLKRALKAA 428
|
|
| PRK06084 |
PRK06084 |
bifunctional O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase; |
19-396 |
5.96e-84 |
|
bifunctional O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase;
Pssm-ID: 180392 [Multi-domain] Cd Length: 425 Bit Score: 262.53 E-value: 5.96e-84
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 19 TQAIHVGQEPEQwSSRAVVLPISLATTFKQDSPGQSS--------GFVYSRSGNPTRNCLEKAVAALDGAKHCLTFASGL 90
Cdd:PRK06084 5 TLAIHAGYSPDP-TTKAVAVPIYQTTSYAFDDTQHGAdlfdlkvpGNIYTRIMNPTNDVLEQRVAALEGGVGALAVASGM 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 91 AATT-TITHLLKAGDEVICMDEVYGGTNRYFRRVASEFGLKISFVDCSKTKLLEAAITPQTKLVWIETPTNPTLKLADIK 169
Cdd:PRK06084 84 AAITyAIQTIAEAGDNIVSVAKLYGGTYNLLAHTLPRIGIETRFAAHDDIAALEALIDERTKAVFCESIGNPAGNIIDIQ 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 170 ACAQIVHKHkDIILVVDNTFMSAYFQRPLALGADICMCSATKYMNGHSDVVMGLVsVNSDDL-----NERLRFLQN---- 240
Cdd:PRK06084 164 ALADAAHRH-GVPLIVDNTVATPVLCRPFEHGADIVVHSLTKYIGGHGTSIGGIV-VDSGKFpwaehKERFALLNTpdps 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 241 -------------------------SLGAVPSPFDCYLCCRGLKTLQIRMEKHFRNGMAVARFLESNPRVEKVIYPGLPS 295
Cdd:PRK06084 242 yhgvtyteafgpaafigrcrvvplrNMGAALSPFNAFLILQGLETLALRMERHTENALKVARYLQQHPQVAWVKYAGLPD 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 296 HPQHELAKRQCTGCP-GMVSFYIKGTLQHAQVFLKNIKLFALAESLGGYESLAELPAIMTHASVPEKDRATLGISDTLIR 374
Cdd:PRK06084 322 HPEHELARRYMGGKPaSILSFGIKGGQAAGARFIDALKLVVRLVNIGDAKSLACHPASTTHRQLNDEELEKAGVSRDMVR 401
|
410 420
....*....|....*....|..
gi 1938958469 375 LSVGLEDEKDLLEDLGQALKAA 396
Cdd:PRK06084 402 LSIGIEHIDDIIADLAQALDAS 423
|
|
| PRK05968 |
PRK05968 |
hypothetical protein; Provisional |
17-396 |
4.88e-83 |
|
hypothetical protein; Provisional
Pssm-ID: 168320 [Multi-domain] Cd Length: 389 Bit Score: 258.86 E-value: 4.88e-83
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 17 FATQAIHVGQEPEQWSSRAVVLPISLATTFKQDS--------PGQSSGFVYSRSGNPTRNCLEKAVAALDGAKHCLTFAS 88
Cdd:PRK05968 7 PFDLAALITAHDEGNAFDAVVPPIFQTSLFTFDSydemedvyAGEKVRPIYSRGDNPTVRAFEEMLAKLEGAEDARGFAS 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 89 GLAA-TTTITHLLKAGDEVICMDEVYGGTNRYFRRVASEFGLKISFVDCSKTKLLEAAItPQTKLVWIETPTNPTLKLAD 167
Cdd:PRK05968 87 GMAAiSSTVLSFVEPGDRIVAVRHVYPDAFRLFETILKRMGVEVDYVDGRDEEAVAKAL-PGAKLLYLESPTSWVFELQD 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 168 IKACAQIVHKHkDIILVVDNTFMSAYFQRPLALGADICMCSATKYMNGHSDVVMGLVsVNSDDLNERLRFLQNS-LGAVP 246
Cdd:PRK05968 166 VAALAALAKRH-GVVTMIDNSWASPVFQRPITLGVDLVIHSASKYLGGHSDTVAGVV-AGSKEHIARINAEAYPyLGAKL 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 247 SPFDCYLCCRGLKTLQIRMEKHFRNGMAVARFLESNPRVEKVIYPGLPSHPQHELakrqcTGCPGMVSFYIKGTLqHAQV 326
Cdd:PRK05968 244 SPFEAWLLLRGLRTLPLRMKAHEASALEIARRLKAHPVVERVCHPALANHPPAGL-----SGTSGLFSFIFREGI-DVRA 317
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1938958469 327 FLKNIKLFALAESLGGYESLAeLPAIMTHASVPEKDR-ATLGISDTLIRLSVGLEDEKDLLEDLGQALKAA 396
Cdd:PRK05968 318 FADALKLFRLGVSWGGHESLV-VPAEVVLQQKAQPNSaARFGVSPRSVRLHVGLEGTEALWADLEQALAAA 387
|
|
| PRK05939 |
PRK05939 |
cystathionine gamma-synthase family protein; |
42-396 |
5.05e-83 |
|
cystathionine gamma-synthase family protein;
Pssm-ID: 235650 [Multi-domain] Cd Length: 397 Bit Score: 259.23 E-value: 5.05e-83
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 42 LATTFKqdspGQSSGFVYSRSGNPTRNCLEKAVAALDGAKHCLTFASGLAA-TTTITHLLKAGDEVICMDEVYGGTNRYF 120
Cdd:PRK05939 28 LIDVFQ----GKKPGFTYARQGTPTTAALEAKITKMEGGVGTVCFATGMAAiAAVFLTLLRAGDHLVSSQFLFGNTNSLF 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 121 RRVAsEFGLKISFVDCSKTKLLEAAITPQTKLVWIETPTNPTLKLADIKACAQIVHKHKdIILVVDNTFMSAYFQRPLAL 200
Cdd:PRK05939 104 GTLR-GLGVEVTMVDATDVQNVAAAIRPNTRMVFVETIANPGTQVADLAGIGALCRERG-LLYVVDNTMTSPWLFRPKDV 181
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 201 GADICMCSATKYMNGHSDVVMGLVS----------VNSDDLNER---------------LRflqnSLGAVPSPFDCYLCC 255
Cdd:PRK05939 182 GASLVINSLSKYIAGHGNALGGAVTdtglfdwsayPNIFPAYRKgdpqqwgltqirkkgLR----DMGATLSSEAAHRIA 257
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 256 RGLKTLQIRMEKHFRNGMAVARFLESNPRVEKVIYPGLPSHPQHELAKRQCTGCPGMVSFYIKGTLQHAQvFLKNIKLFA 335
Cdd:PRK05939 258 IGAETLALRVDRSCSNALALAQFLEAHPKVARVYYPGLASHPQHARATELFRHYGGLLSFELADGIDCFD-FLNRLKLVI 336
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1938958469 336 LAESLGGYESLAeLPAIMT--HASVPEKdRATLGISDTLIRLSVGLEDEKDLLEDLGQALKAA 396
Cdd:PRK05939 337 KATHLGDTRTLV-IPVAPTiyYEMGAER-RASMGIADSLIRVSVGIEDEADLIADFEQALDAT 397
|
|
| PRK07812 |
PRK07812 |
O-acetylhomoserine aminocarboxypropyltransferase; Validated |
16-398 |
1.66e-82 |
|
O-acetylhomoserine aminocarboxypropyltransferase; Validated
Pssm-ID: 236105 Cd Length: 436 Bit Score: 258.91 E-value: 1.66e-82
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 16 HFATQAIHVGQEPEQwSSRAVVLPISLATTFKQDSPGQSS--------GFVYSRSGNPTRNCLEKAVAALDGAKHCLTFA 87
Cdd:PRK07812 13 SFETKQIHAGQTPDP-ATNARALPIYQTTSYTFDDTDHAAalfglaepGNIYTRIMNPTQDVVEQRIAALEGGVAALLLA 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 88 SGLAATT-TITHLLKAGDEVICMDEVYGGTNRYFRRVASEFGLKISFV-DCSKTKLLEAAITPQTKLVWIETPTNPTLKL 165
Cdd:PRK07812 92 SGQAAETfAILNLAGAGDHIVSSPRLYGGTYNLFHYTLPKLGIEVSFVeDPDDLDAWRAAVRPNTKAFFAETISNPQIDV 171
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 166 ADIKACAQIVHKHkDIILVVDNTFMSAYFQRPLALGADICMCSATKYMNGHSDVVMGLV--------------SVNSDD- 230
Cdd:PRK07812 172 LDIPGVAEVAHEA-GVPLIVDNTIATPYLIRPLEHGADIVVHSATKYLGGHGTAIAGVIvdggtfdwtqgrfpGFTTPDp 250
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 231 ----------------LNERLRFLQNsLGAVPSPFDCYLCCRGLKTLQIRMEKHFRNGMAVARFLESNPRVEKVIYPGLP 294
Cdd:PRK07812 251 syhgvvfaelgppayaLKARVQLLRD-LGSAISPFNAFLIAQGLETLSLRIERHVANAQRVAEFLEARDEVASVNYAGLP 329
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 295 SHPQHELAKRQC-TGCPGMVSFYIKGTLQHAQVFLKNIKLFALAESLGGYESLAELPAIMTHASVPEKDRATLGISDTLI 373
Cdd:PRK07812 330 SSPWYERAKRLApKGTGAVLSFELAGGVEAGKAFVNALTLHSHVANIGDVRSLVIHPASTTHSQLTPEEQLATGVTPGLV 409
|
410 420
....*....|....*....|....*
gi 1938958469 374 RLSVGLEDEKDLLEDLGQALKAAHP 398
Cdd:PRK07812 410 RLAVGIEGIDDILADLEAGFAAAKA 434
|
|
| PRK05994 |
PRK05994 |
O-acetylhomoserine aminocarboxypropyltransferase; Validated |
17-396 |
2.20e-82 |
|
O-acetylhomoserine aminocarboxypropyltransferase; Validated
Pssm-ID: 180344 [Multi-domain] Cd Length: 427 Bit Score: 258.49 E-value: 2.20e-82
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 17 FATQAIHVGQEPEQwSSRAVVLPISLATTFKQDSPG--------QSSGFVYSRSGNPTRNCLEKAVAALDGAKHCLTFAS 88
Cdd:PRK05994 8 FATLAVHAGAQPDP-TTGARATPIYQTTSFVFNDADhaaslfglQAFGNIYTRITNPTNAVLEERVAALEGGTAALAVAS 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 89 GLAATTTITH-LLKAGDEVICMDEVYGGTNRYFRRVASEFGLKISFVDCSKTKLLEAAITPQTKLVWIETPTNPTLKLAD 167
Cdd:PRK05994 87 GHAAQFLVFHtLLQPGDEFIAARKLYGGSINQFGHAFKSFGWQVRWADADDPASFERAITPRTKAIFIESIANPGGTVTD 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 168 IKACAQIVHKHKdIILVVDNTFMSAYFQRPLALGADICMCSATKYMNGHSDVVMGL-VSVNSDDLNERLRF--------- 237
Cdd:PRK05994 167 IAAIAEVAHRAG-LPLIVDNTLASPYLIRPIEHGADIVVHSLTKFLGGHGNSMGGIiVDGGTFDWSKSGKYpmlseprpe 245
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 238 -----LQNS-----------------LGAVPSPFDCYLCCRGLKTLQIRMEKHFRNGMAVARFLESNPRVEKVIYPGLPS 295
Cdd:PRK05994 246 yhglvLHETfgnfafaiaarvlglrdLGPAISPFNAFLILTGIETLPLRMQRHSDNALAVAEWLKGHPKVSWVNYAGLPD 325
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 296 HPQHELAKRQCTGCPGMV-SFYIKGTLQHAQVFLKNIKLFALAESLGGYESLAELPAIMTHASVPEKDRATLGISDTLIR 374
Cdd:PRK05994 326 DPYHALAQKYSPKGAGAVfTFGLKGGYEAGVKLVSSLKLFSHLANIGDTRSLVIHPASTTHRQLTDEQKVAAGAGPDVVR 405
|
410 420
....*....|....*....|..
gi 1938958469 375 LSVGLEDEKDLLEDLGQALKAA 396
Cdd:PRK05994 406 LSIGIEDVDDIIADLEQALAKA 427
|
|
| PRK07810 |
PRK07810 |
O-succinylhomoserine sulfhydrylase; Provisional |
11-394 |
3.29e-79 |
|
O-succinylhomoserine sulfhydrylase; Provisional
Pssm-ID: 236103 [Multi-domain] Cd Length: 403 Bit Score: 249.65 E-value: 3.29e-79
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 11 LPSFQHFATQAIHVGQEPEQWSSRAVvlPISLATTFKQDSP--------GQSSGFVYSRSGNPTRNCLEKAVAALDGAKH 82
Cdd:PRK07810 10 LPDGVSQATIGVRGGLLRSGFEETAE--ALYLTSGYVYESAaaaeaaftGELDRFVYSRYGNPTVSMFEERLRLIEGAEA 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 83 CLTFASGLAAT-TTITHLLKAGDEVICMDEVYGGTNRYFRRVASEFGLKISFVDCSKTKLLEAAITPQTKLVWIETPTNP 161
Cdd:PRK07810 88 CFATASGMSAVfTALGALLGAGDRLVAARSLFGSCFVVCNEILPRWGVETVFVDGEDLSQWEEALSVPTQAVFFETPSNP 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 162 TLKLADIKACAQIVHKHKDIIlVVDNTFMSAYFQRPLALGADICMCSATKYMNGHSDVVMGLVSVNSDDLNERLRFLQNS 241
Cdd:PRK07810 168 MQSLVDIAAVSELAHAAGAKV-VLDNVFATPLLQRGLPLGADVVVYSGTKHIDGQGRVLGGAILGDREYIDGPVQKLMRH 246
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 242 LGAVPSPFDCYLCCRGLKTLQIRMEKHFRNGMAVARFLESNPRVEKVIYPGLPSHPQHELAKRQCTGCPGMVSFYIKGTL 321
Cdd:PRK07810 247 TGPALSAFNAWVLLKGLETLALRVRHSNASALRIAEFLEGHPAVRWVRYPFLPSHPQYDLAKRQMSGGGTVVTFELDAPE 326
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1938958469 322 ----QHAQVFLKNIKLFALAESLGGYESLAELPAIMTHASVPEKDRATLGISDTLIRLSVGLEDEKDLLEDLGQALK 394
Cdd:PRK07810 327 daakKRAFEVLDKLRVIDISNNLGDAKSLITHPATTTHRAMGPEGRAAIGLGDGVVRLSVGLEDTDDLIADLDRALG 403
|
|
| cysta_beta_ly_B |
TIGR01324 |
cystathionine beta-lyase, bacterial; This model represents cystathionine beta-lyase (alternate ... |
19-396 |
2.86e-78 |
|
cystathionine beta-lyase, bacterial; This model represents cystathionine beta-lyase (alternate name: beta-cystathionase), one of several pyridoxal-dependent enzymes of cysteine, methionine, and homocysteine metabolism. This enzyme is involved in the biosynthesis of Met from Cys. [Amino acid biosynthesis, Aspartate family]
Pssm-ID: 130391 [Multi-domain] Cd Length: 377 Bit Score: 246.33 E-value: 2.86e-78
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 19 TQAIHVGQEPEQwSSRAVVLPISLATTFKQDSPGQSSG----FVYSRSGNPTRNCLEKAVAALDGAKHCLTFASGLAATT 94
Cdd:TIGR01324 1 TRLIHSGRQPRF-SQGSVNPPLQRASTVLFDSHAAQRRakgeLTYGRRGTLTHFALQDAMCELEGGAGCYLYPSGLAAVT 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 95 -TITHLLKAGDEVICMDEVYGGTNRYFRRVASEFGLKISFVDCSKTKLLEAAITPQTKLVWIETPTNPTLKLADIKACAQ 173
Cdd:TIGR01324 80 nSILAFVKAGDHVLMVDSAYEPTRYFCDIVLKRMGVDITYYDPLIGEDIATLIQPNTKVLFLEAPSSITFEIQDIPAIAK 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 174 IVHKhKDIILVVDNTFMSAYFQRPLALGADICMCSATKYMNGHSDVVMGLVSVNsDDLNERLRFLQNSLGAVPSPFDCYL 253
Cdd:TIGR01324 160 AARN-PGIVIMIDNTWAAGLLFKPLEHGVDISIQAGTKYLVGHSDIMIGTVVAN-ARTWDQLREHSYLMGQMVDADDAYT 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 254 CCRGLKTLQIRMEKHFRNGMAVARFLESNPRVEKVIYPGLPSHPQHELAKRQCTGCPGMVSFYIKGTLQHAQ-VFLKNIK 332
Cdd:TIGR01324 238 TLRGLRTLGVRLKQHQESSLAIAKWLSEQPEVARVLHPALPSCPGHEFWKRDFSGSSGLFSFVLQRLTQKQVhAFLDHLQ 317
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1938958469 333 LFALAESLGGYESLAeLPAIMTHASVPEKDRATLGisdTLIRLSVGLEDEKDLLEDLGQALKAA 396
Cdd:TIGR01324 318 LFGLGYSWGGYESLA-LCNQPELGHRPNIKRNLEG---PLIRVHIGLENVDDLKADLKAGFEAI 377
|
|
| PRK07050 |
PRK07050 |
cystathionine beta-lyase; Provisional |
16-396 |
7.49e-78 |
|
cystathionine beta-lyase; Provisional
Pssm-ID: 180810 [Multi-domain] Cd Length: 394 Bit Score: 245.79 E-value: 7.49e-78
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 16 HFATQAIH-VGQEPEQWSS------RA--VVLPiSLATTFKQDSpGQSSGFVYSRSGNPTRNCLEKAVAALDGAKHCLTF 86
Cdd:PRK07050 9 ALQTRIVQpDDQIPPGFRSfvtpvaRAstVVFP-DLATMRALDW-RQDVQWRYGLHATPTSLALAQRLAEIEGGRHALLQ 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 87 ASGLAATTTITH-LLKAGDEVICMDEVYGGTNRYFRRVASEFGLKISFVDCSKTKLLEAAITPQTKLVWIETPTNPTLKL 165
Cdd:PRK07050 87 PSGLAAISLVYFgLVKAGDDVLIPDNAYGPNRDHGEWLARDFGITVRFYDPLIGAGIADLIQPNTRLIWLEAPGSVTMEV 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 166 ADIKACAQIVHKHkDIILVVDNTFMSAYFQRPLALGADICMCSATKYMNGHSDVVMGLVSVNSDDLNERLRFLQNSLGAV 245
Cdd:PRK07050 167 PDVPAITAAARAR-GVVTAIDNTYSAGLAFKPFEHGVDISVQALTKYQSGGSDVLMGATITADAELHAKLKLARMRLGIG 245
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 246 PSPFDCYLCCRGLKTLQIRMEKHFRNGMAVARFLESNPRVEKVIYPGLPSHPQHELAKRQCTGCPGMVSFYIKGTLQHAQ 325
Cdd:PRK07050 246 VSADDCSLVLRGLPSLQVRLAAHDRSALEVAEWLKARPEIATVLHPALPDCPGHAFWMRDFTGAGGLFSVVFDERYSPAQ 325
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1938958469 326 V--FLKNIKLFALAESLGGYESLAeLPaimthASVPEKDRATLGISDTLIRLSVGLEDEKDLLEDLGQALKAA 396
Cdd:PRK07050 326 VdaFVEALELFAIGWSWGGACSLA-MP-----YDVASMRTAKWPHRGTLVRLYIGLEDEADLIADLEQALEAA 392
|
|
| PRK05967 |
PRK05967 |
cystathionine beta-lyase; Provisional |
52-396 |
1.60e-76 |
|
cystathionine beta-lyase; Provisional
Pssm-ID: 235657 [Multi-domain] Cd Length: 395 Bit Score: 242.41 E-value: 1.60e-76
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 52 GQSSGFVYSRSGNPTRNCLEKAVAALDGAKHCLTFASGLAATTT-ITHLLKAGDEVICMDEVYGGTNRYFRRVASEFGLK 130
Cdd:PRK05967 51 TRGQKYTYGTRGTPTTDALCKAIDALEGSAGTILVPSGLAAVTVpFLGFLSPGDHALIVDSVYYPTRHFCDTMLKRLGVE 130
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 131 ISFVDCSKTKLLEAAITPQTKLVWIETPTNPTLKLADIKACAQIVHKHkDIILVVDNTFMSAYFQRPLALGADICMCSAT 210
Cdd:PRK05967 131 VEYYDPEIGAGIAKLMRPNTKVVHTEAPGSNTFEMQDIPAIAEAAHRH-GAIVMMDNTWATPLYFRPLDFGVDISIHAAT 209
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 211 KYMNGHSDVVMGLVSVNSDDLnERLRFLQNSLGAVPSPFDCYLCCRGLKTLQIRMEKHFRNGMAVARFLESNPRVEKVIY 290
Cdd:PRK05967 210 KYPSGHSDILLGTVSANEKCW-PQLLEAHGTLGLCAGPDDTYQILRGLRTMGIRLEHHRKSALEIARWLEGRPDVARVLH 288
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 291 PGLPSHPQHELAKRQCTGCPGMVSFYIKGTL----QHAQVFLKNIKLFALAESLGGYESLAelpaimTHASVPEKDRATL 366
Cdd:PRK05967 289 PALPSFPGHEIWKRDFSGASGIFSFVLAAGPekgkAKAHAFLDALEIFGLGYSWGGYESLA------LHVKLGDRTVAKA 362
|
330 340 350
....*....|....*....|....*....|
gi 1938958469 367 GISDTLIRLSVGLEDEKDLLEDLGQALKAA 396
Cdd:PRK05967 363 PYAGPVIRLQIGLEDVPDLKADLERGFAAA 392
|
|
| PRK05613 |
PRK05613 |
O-acetylhomoserine/O-acetylserine sulfhydrylase; |
17-395 |
8.06e-73 |
|
O-acetylhomoserine/O-acetylserine sulfhydrylase;
Pssm-ID: 168128 [Multi-domain] Cd Length: 437 Bit Score: 234.00 E-value: 8.06e-73
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 17 FATQAIHVGQePEQWSSRAVVLPISLATTFKQDSPGQSS--------GFVYSRSGNPTRNCLEKAVAALDGAKHCLTFAS 88
Cdd:PRK05613 14 FETRSIHAGQ-SVDSDTSARNLPIYQTTSYVFDSAEHAKqrfaledlGPIYSRLTNPTVEALENRIASLEGGVHAVAFAS 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 89 GLAATT-TITHLLKAGDEVICMDEVYGGTNRYFRRVASEFGLKISFV-DCSKTKLLEAAITPQTKLVWIETPTNPTLKLA 166
Cdd:PRK05613 93 GQAAETaAILNLAGAGDHIVTSPRLYGGTETLFLVTLNRLGIEVTFVeNPDDPESWQAAVQPNTKAFFGETFANPQADVL 172
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 167 DIKACAQIVHKHKdIILVVDNTFMSAYFQRPLALGADICMCSATKYMNGHSDVVMGLV--------SVNSD--------- 229
Cdd:PRK05613 173 DIPAVAEVAHRNQ-VPLIVDNTIATAALVRPLELGADVVVASLTKFYTGNGSGLGGVLidggkfdwTVERDgkpvfpyfv 251
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 230 ------------DLNE-------RLRFLQNSlGAVPSPFDCYLCCRGLKTLQIRMEKHFRNGMAVARFLESNPRVEKVIY 290
Cdd:PRK05613 252 tpdpayhglkyaDLGApafglkaRAGLLRDT-GATLSPFNAWVTAQGLDTLSLRLERHNENAIKVAEFLNNHEKVAKVNF 330
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 291 PGLPSHPQHELAKRQCTGCPGMV-SFYIKGTLQHAQVFLKNIKLFALAESLGGYESLAELPAIMTHASVPEKDRATLGIS 369
Cdd:PRK05613 331 AGLKDSPWYATKEKLGLKYTGSVlSFDIKGGKDEAWAFIDALKLHSNLANIGDVRSLVVHPATTTHSQSDEAGLARAGIT 410
|
410 420
....*....|....*....|....*.
gi 1938958469 370 DTLIRLSVGLEDEKDLLEDLGQALKA 395
Cdd:PRK05613 411 QATVRLSVGIEDIDDIIADLEGGFAA 436
|
|
| PRK09028 |
PRK09028 |
cystathionine beta-lyase; Provisional |
18-389 |
9.22e-69 |
|
cystathionine beta-lyase; Provisional
Pssm-ID: 181615 [Multi-domain] Cd Length: 394 Bit Score: 222.30 E-value: 9.22e-69
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 18 ATQAIHVGQEpEQWSSRAVVLPISLATTFKQDSPGQ---------SSGFVYSRSGNPTRNCLEKAVAALDGAKHCLTFAS 88
Cdd:PRK09028 6 ATKIVSAGRD-KKWTKGVINPPVFRASTVVFDTVAEmrhaaknraNGEMFYGRRGTPTHFAFQAAIVELEGGAGTALYPS 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 89 GLAA-TTTITHLLKAGDEVICMDEVYGGTNRYFRRVASEFGLKISFVDCSKTKLLEAAITPQTKLVWIETPTNPTLKLAD 167
Cdd:PRK09028 85 GAAAiSNALLSFLKAGDHLLMVDSCYEPTRDLCDKILKGFGIETTYYDPMIGEGIRELIRPNTKVLFLESPGSITMEVQD 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 168 IKACAQIVHKHkDIILVVDNTFMSAYFQRPLALGADICMCSATKYMNGHSDVVMGlVSVNSDDLNERLRFLQNSLGAVPS 247
Cdd:PRK09028 165 VPTLSRIAHEH-DIVVMLDNTWASPINSRPFEMGVDISIQAATKYIVGHSDVMLG-TATANEKHWDQLREHSYLMGQCTS 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 248 PFDCYLCCRGLKTLQIRMEKHFRNGMAVARFLESNPRVEKVIYPGLPSHPQHELAKRQCTGCPGMVSFYIK-GTLQHAQV 326
Cdd:PRK09028 243 PDDVYLAMRGLRTLGVRLAQHEKNALKVANWLATRPEVDHVRHPAFETCPGHEFFKRDFSGSNGLFSFVLKqGDPKAVTA 322
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1938958469 327 FLKNIKLFALAESLGGYESLaelpaIMTHASVPEKDRAT-LGISDTLIRLSVGLEDEKDLLEDL 389
Cdd:PRK09028 323 LVEGMQHFKMGFSWGGFESL-----ILGVFGINKLRTATnWDFSKPLIRLHIGLEDVDDLIADL 381
|
|
| PRK08114 |
PRK08114 |
cystathionine beta-lyase; Provisional |
15-389 |
7.03e-61 |
|
cystathionine beta-lyase; Provisional
Pssm-ID: 181231 [Multi-domain] Cd Length: 395 Bit Score: 201.86 E-value: 7.03e-61
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 15 QHFATQAIHVGQEPE--QWSSRAVVLPISlATTF------KQDSPGQSSG-FVYSRSGNPTRNCLEKAVAALDGAKHCLT 85
Cdd:PRK08114 4 KKLDTQLVNAGRSKKytQGSVNSVIQRAS-SLVFdsveakKHATRNRANGeLFYGRRGTLTHFSLQEAMCELEGGAGCAL 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 86 FASGLAA-TTTITHLLKAGDEVICMDEVYGGTNRYFRRVASEFGLKISFVDCSKTKLLEAAITPQTKLVWIETPTNPTLK 164
Cdd:PRK08114 83 YPCGAAAvANAILAFVEQGDHVLMTGTAYEPTQDFCSKILSKLGVTTTWFDPLIGADIAKLIQPNTKVVFLESPGSITME 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 165 LADIKACAQIVH-KHKDIILVVDNTFMSAYFQRPLALGADICMCSATKYMNGHSDVVMGlVSVNSDDLNERLRflQNS-- 241
Cdd:PRK08114 163 VHDVPAIVAAVRsVNPDAVIMIDNTWAAGVLFKALDFGIDISIQAGTKYLVGHSDAMIG-TAVANARCWEQLR--ENSyl 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 242 LGAVPSPFDCYLCCRGLKTLQIRMEKHFRNGMAVARFLESNPRVEKVIYPGLPSHPQHELAKRQCTGCPGMVSFYIKGTL 321
Cdd:PRK08114 240 MGQMVDADTAYMTSRGLRTLGVRLRQHEESSLKVAEWLAEHPEVARVNHPALPGCKGHEFWKRDFTGSSGLFSFVLKKKL 319
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1938958469 322 QHAQV--FLKNIKLFALAESLGGYESLaelpaIMthASVPEKDRA-----TLGISDTLIRLSVGLEDEKDLLEDL 389
Cdd:PRK08114 320 TDEQLanYLDNFSLFSMAYSWGGFESL-----IL--ANQPEEIAAirpagEVDFTGTLIRLHIGLEDVDDLIADL 387
|
|
| PRK06702 |
PRK06702 |
bifunctional O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase; |
18-393 |
8.46e-57 |
|
bifunctional O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase;
Pssm-ID: 102505 [Multi-domain] Cd Length: 432 Bit Score: 192.19 E-value: 8.46e-57
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 18 ATQAIHVGQEPEQWSSRavVLPISLATTFKQDSPG--------QSSGFVYSRSGNPTRNCLEKAVAALDGAKHCLTFASG 89
Cdd:PRK06702 8 GTICVQGGYTPKNGEPR--VLPLYQSTTYKYDTSDdlaalfnlEAEGYIYTRIGNPTLAAFEQKLAELEGGVGAVATASG 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 90 LAATT-TITHLLKAGDEVICMDEVYGGTNRYFRRVASEFGLKISFVDCSKT-KLLEAAITPQTKLVWIETPTNPTLKLAD 167
Cdd:PRK06702 86 QAAIMlAVLNICSSGDHLLCSSTVYGGTFNLFGVSLRKLGIDVTFFNPNLTaDEIVALANDKTKLVYAESLGNPAMNVLN 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 168 IKACAQIVhKHKDIILVVDNTFMSAYFQRPLALGADICMCSATKYMNGHSDVVMGLVS---------------VNSDDLN 232
Cdd:PRK06702 166 FKEFSDAA-KELEVPFIVDNTLATPYLCQAFEHGANIIVHSTTKYIDGHASSLGGIVIdggnfdwtngkypelVEPDPSY 244
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 233 ERLRFLQN----------------SLGAVPSPFDCYLCCRGLKTLQIRMEKHFRNGMAVARFLESNPRVEKVIYPGLPSH 296
Cdd:PRK06702 245 HGVSYVQNfgaaayivkarvqllrDYGNCMSPFNAYISNIGLETLHLRMERHSENALAVAKWLADHERIEWVNYPGLDSN 324
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 297 PQHELAKRQCT-GCPGMVSFYIKGTLQHAQVFLKNIKLFALAESLGGYESLAELPAIMTHASVPEKDRATLGISDTLIRL 375
Cdd:PRK06702 325 ENYSLAQKYLKkGASGVLTFGIKGGLEAAKEFIANVKLATLVTHVADARTCVIHPASTTHRQLSAEDQRLAGVTSDLIRL 404
|
410
....*....|....*...
gi 1938958469 376 SVGLEDEKDLLEDLGQAL 393
Cdd:PRK06702 405 SVGIEDVSDIIADLEAAL 422
|
|
| PLN02242 |
PLN02242 |
methionine gamma-lyase |
57-394 |
9.23e-55 |
|
methionine gamma-lyase
Pssm-ID: 215134 Cd Length: 418 Bit Score: 186.51 E-value: 9.23e-55
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 57 FVYSRSGNPTRNCLEKAVAALDGAKHCLTFASGLAA-TTTITHLLKAGDEVICMDEVYGGTNRYFRR-VASEFGLKISFV 134
Cdd:PLN02242 68 YIYSRHFNPTVLNLGRQMAALEGTEAAYCTASGMSAiSSVLLQLCSSGGHVVASNTLYGGTHALLAHfLPRKCNITTTFV 147
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 135 DCSKTKLLEAAITP-QTKLVWIETPTNPTLKLADIKACAQIVHKhKDIILVVDNTFmSAYFQRPLALGADICMCSATKYM 213
Cdd:PLN02242 148 DITDLEAVKKAVVPgKTKVLYFESISNPTLTVADIPELARIAHE-KGVTVVVDNTF-APMVLSPARLGADVVVHSISKFI 225
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 214 NGHSDVVMGLVSVNSDDLNERLRFLQNS---LGAVPSPFDCYLCCRGLKTLQIRMEKHFRNGMAVARFLESNPRveKVIY 290
Cdd:PLN02242 226 SGGADIIAGAVCGPAELVNSMMDLHHGAlmlLGPTMNPKVAFELSERLPHLSLRMKEHCRRAMEYAKRMKELGL--KVIY 303
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 291 PGLPSHPQHELAKRQ---CTGCPGMVSFYIkGTLQHAQVF---LKNIKLFAL-AESLGGYESLAELPAIMTHASVPEKDR 363
Cdd:PLN02242 304 PGLEDHPQHALLKSMankGYGFGGLLCLDM-DTEERANRLmryLQNSTQFGFmAVSLGYYETLMSCSGSSTSSELDPEEK 382
|
330 340 350
....*....|....*....|....*....|....*
gi 1938958469 364 ATLGISDTLIRLSVG----LEDEKDLLEDLGQALK 394
Cdd:PLN02242 383 AAAGISPGLVRMSVGytgtLEQRWSQFEKALSAMK 417
|
|
| AAT_I |
cd01494 |
Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP) ... |
70-215 |
7.30e-14 |
|
Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the substrate in four kinds of reactions (1) transamination (movement of amino groups), (2) racemization (redistribution of enantiomers), (3) decarboxylation (removing COOH groups), and (4) various side-chain reactions depending on the enzyme involved. Pyridoxal phosphate (PLP) dependent enzymes were previously classified into alpha, beta and gamma classes, based on the chemical characteristics (carbon atom involved) of the reaction they catalyzed. The availability of several structures allowed a comprehensive analysis of the evolutionary classification of PLP dependent enzymes, and it was found that the functional classification did not always agree with the evolutionary history of these enzymes. Structure and sequence analysis has revealed that the PLP dependent enzymes can be classified into four major groups of different evolutionary origin: aspartate aminotransferase superfamily (fold type I), tryptophan synthase beta superfamily (fold type II), alanine racemase superfamily (fold type III), and D-amino acid superfamily (fold type IV) and Glycogen phophorylase family (fold type V).
Pssm-ID: 99742 [Multi-domain] Cd Length: 170 Bit Score: 68.95 E-value: 7.30e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 70 LEKAVAAL--DGAKHCLTFASGLAATTTITH-LLKAGDEVICMDEVYGGTNRyfrRVASEFGLKISFVD--------CSK 138
Cdd:cd01494 5 LEEKLARLlqPGNDKAVFVPSGTGANEAALLaLLGPGDEVIVDANGHGSRYW---VAAELAGAKPVPVPvddagyggLDV 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 139 TKLLEAAITPQTKLVWIETPTNPTLKLADIKACAQIVHKHkDIILVVDNTF----MSAYFQRPLALGADICMCSATKYMN 214
Cdd:cd01494 82 AILEELKAKPNVALIVITPNTTSGGVLVPLKEIRKIAKEY-GILLLVDAASaggaSPAPGVLIPEGGADVVTFSLHKNLG 160
|
.
gi 1938958469 215 G 215
Cdd:cd01494 161 G 161
|
|
| WecE |
COG0399 |
dTDP-4-amino-4,6-dideoxygalactose transaminase [Cell wall/membrane/envelope biogenesis]; |
70-240 |
3.77e-11 |
|
dTDP-4-amino-4,6-dideoxygalactose transaminase [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440168 Cd Length: 364 Bit Score: 63.93 E-value: 3.77e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 70 LEKAVAALDGAKHCLTFASGLAATTTITHLL--KAGDEVICmdevyggTNRYFrrVAS-----EFGLKISFVDCSK---- 138
Cdd:COG0399 35 FEEEFAAYLGVKHAVAVSSGTAALHLALRALgiGPGDEVIT-------PAFTF--VATanailYVGATPVFVDIDPdtyn 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 139 --TKLLEAAITPQTKLVwIetPT----NPtlklADIKACAQIVHKHkDIILVVDN--TFMSAYFQRPLALGADICMCS-- 208
Cdd:COG0399 106 idPEALEAAITPRTKAI-I--PVhlygQP----ADMDAIMAIAKKH-GLKVIEDAaqALGATYKGKKVGTFGDAGCFSfy 177
|
170 180 190
....*....|....*....|....*....|....*
gi 1938958469 209 ATK---YMNGhsdvvmGLVSVNSDDLNERLRFLQN 240
Cdd:COG0399 178 PTKnltTGEG------GAVVTNDEELAERARSLRN 206
|
|
| AAT_like |
cd00609 |
Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent ... |
99-306 |
2.99e-10 |
|
Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the substrate in four kinds of reactions (1) transamination (movement of amino groups), (2) racemization (redistribution of enantiomers), (3) decarboxylation (removing COOH groups), and (4) various side-chain reactions depending on the enzyme involved. Pyridoxal phosphate (PLP) dependent enzymes were previously classified into alpha, beta and gamma classes, based on the chemical characteristics (carbon atom involved) of the reaction they catalyzed. The availability of several structures allowed a comprehensive analysis of the evolutionary classification of PLP dependent enzymes, and it was found that the functional classification did not always agree with the evolutionary history of these enzymes. The major groups in this CD corresponds to Aspartate aminotransferase a, b and c, Tyrosine, Alanine, Aromatic-amino-acid, Glutamine phenylpyruvate, 1-Aminocyclopropane-1-carboxylate synthase, Histidinol-phosphate, gene products of malY and cobC, Valine-pyruvate aminotransferase and Rhizopine catabolism regulatory protein.
Pssm-ID: 99734 [Multi-domain] Cd Length: 350 Bit Score: 61.20 E-value: 2.99e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 99 LLKAGDEVICMDEVYGGtnryFRRVASEFGLKISFVDCSK-------TKLLEAAITPQTKLVWIETPTNPT---LKLADI 168
Cdd:cd00609 79 LLNPGDEVLVPDPTYPG----YEAAARLAGAEVVPVPLDEeggflldLELLEAAKTPKTKLLYLNNPNNPTgavLSEEEL 154
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 169 KACAQIVHKHkDIILVVDNT---FMSAYFQRPLALGAD-----ICMCSATKYMNghsdvVMGL----VSVNSDDLNERLR 236
Cdd:cd00609 155 EELAELAKKH-GILIISDEAyaeLVYDGEPPPALALLDayervIVLRSFSKTFG-----LPGLrigyLIAPPEELLERLK 228
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 237 FLQNSLGAVPSPFDCYLCCRGLKTLQIRMEKHF----RNGMAVARFLESNPRVEKV-------IYPGLPSHPQHELAKRQ 305
Cdd:cd00609 229 KLLPYTTSGPSTLSQAAAAAALDDGEEHLEELReryrRRRDALLEALKELGPLVVVkpsggffLWLDLPEGDDEEFLERL 308
|
.
gi 1938958469 306 C 306
Cdd:cd00609 309 L 309
|
|
| AHBA_syn |
cd00616 |
3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal ... |
70-240 |
1.04e-09 |
|
3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary metabolites. Some well studied proteins in this CD are AHBA_synthase, protein product of pleiotropic regulatory gene degT, Arnb aminotransferase and pilin glycosylation protein. The prototype of this family, the AHBA_synthase, is a dimeric PLP dependent enzyme. AHBA_syn is the terminal enzyme of 3-amino-5-hydroxybenzoic acid (AHBA) formation which is involved in the biosynthesis of ansamycin antibiotics, including rifamycin B. Some members of this CD are involved in 4-amino-6-deoxy-monosaccharide D-perosamine synthesis. Perosamine is an important element in the glycosylation of several cell products, such as antibiotics and lipopolysaccharides of gram-positive and gram-negative bacteria. The pilin glycosylation protein encoded by gene pglA, is a galactosyltransferase involved in pilin glycosylation. Additionally, this CD consists of ArnB (PmrH) aminotransferase, a 4-amino-4-deoxy-L-arabinose lipopolysaccharide-modifying enzyme. This CD also consists of several predicted pyridoxal phosphate-dependent enzymes apparently involved in regulation of cell wall biogenesis. The catalytic lysine which is present in all characterized PLP dependent enzymes is replaced by histidine in some members of this CD.
Pssm-ID: 99740 [Multi-domain] Cd Length: 352 Bit Score: 59.48 E-value: 1.04e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 70 LEKAVAALDGAKHCLTFASGLAATTTITHLL--KAGDEVICmdevyggTNRYFrrVAS-----EFGLKISFVDCSKT--- 139
Cdd:cd00616 23 FEKAFAEYLGVKYAVAVSSGTAALHLALRALgiGPGDEVIV-------PSFTF--VATanailLLGATPVFVDIDPDtyn 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 140 ---KLLEAAITPQTKLVwieTPTNPTLKLADIKACAQIVHKHkDIILVVDN--TFMSAYFQRPLALGADICMCS--ATK- 211
Cdd:cd00616 94 idpELIEAAITPRTKAI---IPVHLYGNPADMDAIMAIAKRH-GLPVIEDAaqALGATYKGRKVGTFGDAGAFSfhPTKn 169
|
170 180 190
....*....|....*....|....*....|.
gi 1938958469 212 --YMNGhsdvvmGLVSVNSDDLNERLRFLQN 240
Cdd:cd00616 170 ltTGEG------GAVVTNDEELAERARLLRN 194
|
|
| PRK09082 |
PRK09082 |
methionine aminotransferase; Validated |
65-186 |
4.06e-09 |
|
methionine aminotransferase; Validated
Pssm-ID: 181642 [Multi-domain] Cd Length: 386 Bit Score: 58.00 E-value: 4.06e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 65 PTRNCLEKAVAALDG----AKHCLTFASGlaAT----TTITHLLKAGDEVICMDEVY----------GGTnryFRRVASE 126
Cdd:PRK09082 71 ALREAIAAKTARLYGrqydADSEITVTAG--ATealfAAILALVRPGDEVIVFDPSYdsyapaielaGGR---AVRVALQ 145
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1938958469 127 FGlkiSF-VDCSKtklLEAAITPQTKLVWIETPTNPT---LKLADIKACAQIVHKHkDIILVVD 186
Cdd:PRK09082 146 PP---DFrVDWQR---FAAAISPRTRLIILNTPHNPSgtvWSAADMRALWQLIAGT-DIYVLSD 202
|
|
| AspB |
COG0436 |
Aspartate/methionine/tyrosine aminotransferase [Amino acid transport and metabolism]; ... |
74-187 |
4.35e-09 |
|
Aspartate/methionine/tyrosine aminotransferase [Amino acid transport and metabolism]; Aspartate/methionine/tyrosine aminotransferase is part of the Pathway/BioSystem: Isoleucine, leucine, valine biosynthesis
Pssm-ID: 440205 [Multi-domain] Cd Length: 387 Bit Score: 57.83 E-value: 4.35e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 74 VAALDGAKHCLTFAsgLAAtttithLLKAGDEVICMDEVYGgTNRYFRRVAsefGLKISFVDCSKT-------KLLEAAI 146
Cdd:COG0436 93 ILVTNGAKEALALA--LLA------LLNPGDEVLVPDPGYP-SYRAAVRLA---GGKPVPVPLDEEngflpdpEALEAAI 160
|
90 100 110 120
....*....|....*....|....*....|....*....|....
gi 1938958469 147 TPQTKLVWIETPTNPT---LKLADIKACAQIVHKHkDIILVVDN 187
Cdd:COG0436 161 TPRTKAIVLNSPNNPTgavYSREELEALAELAREH-DLLVISDE 203
|
|
| DegT_DnrJ_EryC1 |
pfam01041 |
DegT/DnrJ/EryC1/StrS aminotransferase family; The members of this family are probably all ... |
70-240 |
2.01e-08 |
|
DegT/DnrJ/EryC1/StrS aminotransferase family; The members of this family are probably all pyridoxal-phosphate-dependent aminotransferase enzymes with a variety of molecular functions. The family includes StsA, StsC and StsS. The aminotransferase activity was demonstrated for purified StsC protein as the L-glutamine:scyllo-inosose aminotransferase EC:2.6.1.50, which catalyzes the first amino transfer in the biosynthesis of the streptidine subunit of streptomycin.
Pssm-ID: 395827 Cd Length: 360 Bit Score: 55.37 E-value: 2.01e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 70 LEKAVAALDGAKHCLTFASGLAATTTITHLLKA--GDEVICMDEVYGGTNryfrRVASEFGLKISFVD------CSKTKL 141
Cdd:pfam01041 29 FERAFAAYLGVKHAIAVSSGTAALHLALRALGVgpGDEVITPSFTFVATA----NAALRLGAKPVFVDidpdtyNIDPEA 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 142 LEAAITPQTKLVwieTPTNPTLKLADIKACAQIVHKHkDIILVVD--NTFMSAYFQRPLALGADICMCS--ATKYM---N 214
Cdd:pfam01041 105 IEAAITPRTKAI---IPVHLYGQPADMDAIRAIAARH-GLPVIEDaaHALGATYQGKKVGTLGDAATFSfhPTKNLttgE 180
|
170 180
....*....|....*....|....*.
gi 1938958469 215 GhsdvvmGLVSVNSDDLNERLRFLQN 240
Cdd:pfam01041 181 G------GAVVTNDPELAEKARVLRN 200
|
|
| YnbB |
COG4100 |
Cystathionine beta-lyase family protein involved in aluminum resistance [Inorganic ion ... |
54-205 |
2.22e-08 |
|
Cystathionine beta-lyase family protein involved in aluminum resistance [Inorganic ion transport and metabolism, General function prediction only];
Pssm-ID: 443276 Cd Length: 409 Bit Score: 55.50 E-value: 2.22e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 54 SSGFVYSRSGnptRNCLEKAVAALDGAKHCL---TFASGL-AATTTITHLLKAGDEVIC--------MDEVYGGTNRYfr 121
Cdd:COG4100 49 TTGYGYDDIG---RDTLERVYADVFGAEDALvrpQIVSGThAIALALFGVLRPGDELLSitgkpydtLEEVIGIRGEG-- 123
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 122 rVAS--EFGLKISFVDCSKT-----KLLEAAITPQTKLVWIETPT----NPTLKLADIKACAQIVHKHK-DIILVVDNtf 189
Cdd:COG4100 124 -QGSlkEFGISYRQVPLTEDgkidlEAIKKAINEKTKMVLIQRSRgyswRPSLTIEEIGEIIKFVKSINpDVICFVDN-- 200
|
170 180
....*....|....*....|.
gi 1938958469 190 msAY--F---QRPLALGADIC 205
Cdd:COG4100 201 --CYgeFvetREPTEVGADLM 219
|
|
| PRK15407 |
PRK15407 |
lipopolysaccharide biosynthesis protein RfbH; Provisional |
71-187 |
5.09e-07 |
|
lipopolysaccharide biosynthesis protein RfbH; Provisional
Pssm-ID: 237960 Cd Length: 438 Bit Score: 51.42 E-value: 5.09e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 71 EKAVAALDGAKHCLTFASG----LAATTTIT-HLL-----KAGDEVICmdevyggtnryfrrVASEF----------GLK 130
Cdd:PRK15407 69 EKKLAEFLGVRYALLVNSGssanLLAFSALTsPKLgdralKPGDEVIT--------------VAAGFpttvnpiiqnGLV 134
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1938958469 131 ISFVDCS------KTKLLEAAITPQTKLVWI-ETPTNPTlklaDIKACAQIVHKHkDIILVVDN 187
Cdd:PRK15407 135 PVFVDVElptyniDASLLEAAVSPKTKAIMIaHTLGNPF----DLAAVKAFCDKH-NLWLIEDN 193
|
|
| PRK05764 |
PRK05764 |
aspartate aminotransferase; Provisional |
79-186 |
1.31e-06 |
|
aspartate aminotransferase; Provisional
Pssm-ID: 235596 Cd Length: 393 Bit Score: 50.12 E-value: 1.31e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 79 GAKHCLTFAsgLAAtttithLLKAGDEVI-------CMDEV---YGGTNRyFRRVASEFGLKISFVDcsktklLEAAITP 148
Cdd:PRK05764 99 GAKQALYNA--FMA------LLDPGDEVIipapywvSYPEMvklAGGVPV-FVPTGEENGFKLTVEQ------LEAAITP 163
|
90 100 110 120
....*....|....*....|....*....|....*....|.
gi 1938958469 149 QTKLVWIETPTNPT---LKLADIKACAQIVHKHkDIILVVD 186
Cdd:PRK05764 164 KTKALILNSPSNPTgavYSPEELEAIADVAVEH-DIWVLSD 203
|
|
| Aminotran_1_2 |
pfam00155 |
Aminotransferase class I and II; |
70-186 |
1.72e-06 |
|
Aminotransferase class I and II;
Pssm-ID: 395103 [Multi-domain] Cd Length: 351 Bit Score: 49.61 E-value: 1.72e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 70 LEKAVAALDGAKHCLTFASGLAATTT----------ITHLLKAGDEVICMDEVYGGTNRYFRRVasefGLKISFVDCSKT 139
Cdd:pfam00155 44 LREALAKFLGRSPVLKLDREAAVVFGsgaganiealIFLLANPGDAILVPAPTYASYIRIARLA----GGEVVRYPLYDS 119
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*..
gi 1938958469 140 KL-------LEAAITPQTKLVWIETPTNPT---LKLADIKACAQIVHKHKdIILVVD 186
Cdd:pfam00155 120 NDfhldfdaLEAALKEKPKVVLHTSPHNPTgtvATLEELEKLLDLAKEHN-ILLLVD 175
|
|
| PRK07777 |
PRK07777 |
putative succinyldiaminopimelate transaminase DapC; |
91-199 |
1.05e-05 |
|
putative succinyldiaminopimelate transaminase DapC;
Pssm-ID: 236095 [Multi-domain] Cd Length: 387 Bit Score: 47.34 E-value: 1.05e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 91 AATTTITHLLKAGDEVICMDEVY----------GGTNRYFRRVASEFGLKISfVDCsktklLEAAITPQTKLVWIETPTN 160
Cdd:PRK07777 97 AIAAAVLGLVEPGDEVLLIEPYYdsyaaviamaGAHRVPVPLVPDGRGFALD-LDA-----LRAAVTPRTRALIVNSPHN 170
|
90 100 110 120
....*....|....*....|....*....|....*....|....*.
gi 1938958469 161 PT---LKLADIKACAQIVHKHkDIILVVDNTFMSAYF----QRPLA 199
Cdd:PRK07777 171 PTgtvLTAAELAAIAELAVEH-DLLVITDEVYEHLVFdgarHLPLA 215
|
|
| HisC |
COG0079 |
Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase [Amino acid ... |
96-190 |
2.78e-05 |
|
Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase [Amino acid transport and metabolism]; Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase is part of the Pathway/BioSystem: Cobalamine/B12 biosynthesis
Pssm-ID: 439849 [Multi-domain] Cd Length: 341 Bit Score: 45.89 E-value: 2.78e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 96 ITHLLKA----GDEVICMD---EVYggtnryfRRVASEFGLKISFVDCSKT-----KLLEAAITPQTKLVWIETPTNPT- 162
Cdd:COG0079 78 IQLLARAflgpGDEVLVPEptfSEY-------PIAARAAGAEVVEVPLDEDfsldlDALLAAITERTDLVFLCNPNNPTg 150
|
90 100 110
....*....|....*....|....*....|
gi 1938958469 163 --LKLADIKACAQIVhkHKDIILVVDNTFM 190
Cdd:COG0079 151 tlLPREELEALLEAL--PADGLVVVDEAYA 178
|
|
| PRK07683 |
PRK07683 |
aminotransferase A; Validated |
99-197 |
6.67e-05 |
|
aminotransferase A; Validated
Pssm-ID: 236075 Cd Length: 387 Bit Score: 44.71 E-value: 6.67e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 99 LLKAGDEVICMDEVYGGTNRYFRRVasefGLKISFVDCSKT------KLLEAAITPQTKLVWIETPTNPTLKLADIKACA 172
Cdd:PRK07683 109 ILEPGTEVILPAPIYPGYEPIIRLC----GAKPVFIDTRSTgfrltaEALENAITEKTRCVVLPYPSNPTGVTLSKEELQ 184
|
90 100
....*....|....*....|....*..
gi 1938958469 173 QIVH--KHKDIILVVDNTFMSAYFQRP 197
Cdd:PRK07683 185 DIADvlKDKNIFVLSDEIYSELVYEQP 211
|
|
| PRK06107 |
PRK06107 |
aspartate transaminase; |
79-189 |
1.14e-04 |
|
aspartate transaminase;
Pssm-ID: 180403 Cd Length: 402 Bit Score: 43.96 E-value: 1.14e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 79 GAKHCLTFAsgLAATttithlLKAGDEVIC----------MDEVYGGTNryfrrvasefglkiSFVDCSKT---KL---- 141
Cdd:PRK06107 101 GAKQAIFLA--LMAT------LEAGDEVIIpapywvsypdMVLANDGTP--------------VIVACPEEqgfKLtpea 158
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|.
gi 1938958469 142 LEAAITPQTKLVWIETPTNPT---LKLADIKACAQIVHKHKDIILVVDNTF 189
Cdd:PRK06107 159 LEAAITPRTRWLILNAPSNPTgavYSRAELRALADVLLRHPHVLVLTDDIY 209
|
|
| PRK07309 |
PRK07309 |
pyridoxal phosphate-dependent aminotransferase; |
91-186 |
1.30e-04 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 235985 Cd Length: 391 Bit Score: 43.94 E-value: 1.30e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 91 AATTTITHLLKAGDEVICMDEVYGGtnryFRRVASEFGLKISFVDCSKT------KLLEAAITPQ---TKLVWIETPTNP 161
Cdd:PRK07309 103 ALSASLTAILEPGDKVLLPAPAYPG----YEPIVNLVGAEIVEIDTTENdfvltpEMLEKAILEQgdkLKAVILNYPANP 178
|
90 100
....*....|....*....|....*...
gi 1938958469 162 T---LKLADIKACAQIVHKHkDIILVVD 186
Cdd:PRK07309 179 TgvtYSREQIKALADVLKKY-DIFVISD 205
|
|
| PRK08912 |
PRK08912 |
aminotransferase; |
70-186 |
3.19e-04 |
|
aminotransferase;
Pssm-ID: 181580 Cd Length: 387 Bit Score: 42.65 E-value: 3.19e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 70 LEKAVAALDGAKHCLTF--------ASGL--AATTTITHLLKAGDEVICMDEVY----------GGTNRYFRRVASEFGL 129
Cdd:PRK08912 68 LRQAVAAHYARFQGLDLdpetevmvTSGAteALAAALLALVEPGDEVVLFQPLYdaylplirraGGVPRLVRLEPPHWRL 147
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 130 KisfvdcskTKLLEAAITPQTKLVWIETPTNPTLKL---ADIKACAQIVHKHkDIILVVD 186
Cdd:PRK08912 148 P--------RAALAAAFSPRTKAVLLNNPLNPAGKVfprEELALLAEFCQRH-DAVAICD 198
|
|
| PRK06836 |
PRK06836 |
pyridoxal phosphate-dependent aminotransferase; |
96-186 |
4.81e-04 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 180720 Cd Length: 394 Bit Score: 42.10 E-value: 4.81e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 96 ITHLLKA----GDEVICMD----------EVYGGTNRYFRRVASEFGLKIsfvdcsktKLLEAAITPQTKLVWIETPTNP 161
Cdd:PRK06836 109 LNVALKAilnpGDEVIVFApyfveyrfyvDNHGGKLVVVPTDTDTFQPDL--------DALEAAITPKTKAVIINSPNNP 180
|
90 100 110
....*....|....*....|....*....|....
gi 1938958469 162 T--------LK-LADIKACAQIVHKHkDIILVVD 186
Cdd:PRK06836 181 TgvvyseetLKaLAALLEEKSKEYGR-PIYLISD 213
|
|
| PRK07682 |
PRK07682 |
aminotransferase; |
142-186 |
6.02e-04 |
|
aminotransferase;
Pssm-ID: 181082 [Multi-domain] Cd Length: 378 Bit Score: 41.64 E-value: 6.02e-04
10 20 30 40
....*....|....*....|....*....|....*....|....*...
gi 1938958469 142 LEAAITPQTKLVWIETPTNPT---LKLADIKACAQIVHKHkDIILVVD 186
Cdd:PRK07682 147 IEAAITAKTKAILLCSPNNPTgavLNKSELEEIAVIVEKH-DLIVLSD 193
|
|
| PRK06348 |
PRK06348 |
pyridoxal phosphate-dependent aminotransferase; |
140-197 |
1.02e-03 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 180537 Cd Length: 384 Bit Score: 40.86 E-value: 1.02e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1938958469 140 KLLEAAITPQTKLVWIETPTNPT---LKLADIKACAQIVHKHkDIILVVDNTFMSAYFQRP 197
Cdd:PRK06348 153 KKLEALITSKTKAIILNSPNNPTgavFSKETLEEIAKIAIEY-DLFIISDEVYDGFSFYED 212
|
|
| PRK12414 |
PRK12414 |
putative aminotransferase; Provisional |
95-189 |
1.34e-03 |
|
putative aminotransferase; Provisional
Pssm-ID: 183514 Cd Length: 384 Bit Score: 40.54 E-value: 1.34e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 95 TITHLLKAGDEVICMDEVYGGTNRYFR-RVASEFGLKISF----VDCSKtklLEAAITPQTKLVWIETPTNPT---LKLA 166
Cdd:PRK12414 106 AISALVHPGDEVIYFEPSFDSYAPIVRlQGATPVAIKLSPedfrVNWDE---VAAAITPRTRMIIVNTPHNPSatvFSAA 182
|
90 100
....*....|....*....|...
gi 1938958469 167 DIKACAQIVhKHKDIILVVDNTF 189
Cdd:PRK12414 183 DLARLAQLT-RNTDIVILSDEVY 204
|
|
| PRK06108 |
PRK06108 |
pyridoxal phosphate-dependent aminotransferase; |
142-194 |
2.77e-03 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 180404 Cd Length: 382 Bit Score: 39.54 E-value: 2.77e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*.
gi 1938958469 142 LEAAITPQTKLVWIETPTNPT---LKLADIKACAQIVHKHkDIILVVDNTFMSAYF 194
Cdd:PRK06108 151 LLAAITPRTRALFINSPNNPTgwtASRDDLRAILAHCRRH-GLWIVADEVYERLYY 205
|
|
| CsdA |
COG0520 |
Selenocysteine lyase/Cysteine desulfurase [Amino acid transport and metabolism]; |
100-186 |
8.92e-03 |
|
Selenocysteine lyase/Cysteine desulfurase [Amino acid transport and metabolism];
Pssm-ID: 440286 [Multi-domain] Cd Length: 396 Bit Score: 37.81 E-value: 8.92e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938958469 100 LKAGDEVIcmdevyggTNRY--------FRRVASEFGLKISFVDCSKT-----KLLEAAITPQTKLV---WIetpTNPTL 163
Cdd:COG0520 100 LKPGDEIL--------ITEMehhsnivpWQELAERTGAEVRVIPLDEDgeldlEALEALLTPRTKLVavtHV---SNVTG 168
|
90 100
....*....|....*....|...
gi 1938958469 164 KLADIKACAQIVHKHkDIILVVD 186
Cdd:COG0520 169 TVNPVKEIAALAHAH-GALVLVD 190
|
|
| |
