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Conserved domains on  [gi|186700616|ref|NP_071990|]
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phosphoribosyl pyrophosphate synthase-associated protein 1 [Rattus norvegicus]

Protein Classification

phosphoribosyl pyrophosphate synthase-associated protein( domain architecture ID 11226557)

phosphoribosyl pyrophosphate synthase-associated protein seems to play a negative regulatory role in 5-phosphoribose 1-diphosphate synthesis

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Pribosyl_synth pfam14572
Phosphoribosyl synthetase-associated domain; This family includes several examples of enzymes ...
 196-379 4.49e-107

Phosphoribosyl synthetase-associated domain; This family includes several examples of enzymes from class EC:2.7.6.1, phosphoribosyl-pyrophosphate transferase.


:

Pssm-ID: 434046  Cd Length: 184  Bit Score: 312.52  E-value: 4.49e-107
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 186700616  196 NYRNAVIVAKSPDAAKRAQSYAERLRLGLAVIHGEAQCTELDMDDGRHSPPMVKNATVHPGLELPLMMAKEKPPITVVGD 275
Cdd:pfam14572   1 DYRNAVIVARSPGSAKRATSFAERLRLGIAVIHGEQKEAESDEVDGRQSPPPYRSRTVSRSLGLPEIIPKEKPPMTVVGD 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 186700616  276 VGGRIAIIVDDIIDDVESFVAAAETLKERGAYKIYVMATHGILSAEAPRLIEESPIDEVVVTNTVPHELQKLQCPKIKTV 355
Cdd:pfam14572  81 VGGRIAIIVDDMIDDVDSFVAAAELLKERGAYKIYVMATHGLLSSDAPRLLEASPIDEVVVTNTIPHEIQKMQCHKIKTI 160

                         170       180
                  ....*....|....*....|....
gi 186700616  356 DISLILSEAIRRIHNGESMAYLFR 379
Cdd:pfam14572 161 DISQLIAEAIRRIHNGESMSYLFR 184
Pribosyltran_N pfam13793
N-terminal domain of ribose phosphate pyrophosphokinase; This family is frequently found ...
 38-155 1.48e-48

N-terminal domain of ribose phosphate pyrophosphokinase; This family is frequently found N-terminal to the Pribosyltran, pfam00156.


:

Pssm-ID: 433483 [Multi-domain]  Cd Length: 117  Bit Score: 160.28  E-value: 1.48e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 186700616   38 RVFSANStaaCTELAKRITERLGAELGKSVVYQETNGETRVEIKESVRGQDIFIIQTIPRDVNTAVMELLIMAYALKTAC 117
Cdd:pfam13793   2 KIFSGNS---NPELAEKIAKRLGIPLGKATVSRFSDGEIYVRIEESVRGKDVFIIQSTCPPVNDNLMELLIMIDALKRAS 78

                          90       100       110
                  ....*....|....*....|....*....|....*....
gi 186700616  118 ARNIIGVIPYFPYSKQSKM-RKRGSIVCKLLASMLAKAG 155
Cdd:pfam13793  79 AKRITAVIPYFGYARQDRKdKPREPITAKLVADLLEAAG 117
 
Name Accession Description Interval E-value
Pribosyl_synth pfam14572
Phosphoribosyl synthetase-associated domain; This family includes several examples of enzymes ...
 196-379 4.49e-107

Phosphoribosyl synthetase-associated domain; This family includes several examples of enzymes from class EC:2.7.6.1, phosphoribosyl-pyrophosphate transferase.


Pssm-ID: 434046  Cd Length: 184  Bit Score: 312.52  E-value: 4.49e-107
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 186700616  196 NYRNAVIVAKSPDAAKRAQSYAERLRLGLAVIHGEAQCTELDMDDGRHSPPMVKNATVHPGLELPLMMAKEKPPITVVGD 275
Cdd:pfam14572   1 DYRNAVIVARSPGSAKRATSFAERLRLGIAVIHGEQKEAESDEVDGRQSPPPYRSRTVSRSLGLPEIIPKEKPPMTVVGD 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 186700616  276 VGGRIAIIVDDIIDDVESFVAAAETLKERGAYKIYVMATHGILSAEAPRLIEESPIDEVVVTNTVPHELQKLQCPKIKTV 355
Cdd:pfam14572  81 VGGRIAIIVDDMIDDVDSFVAAAELLKERGAYKIYVMATHGLLSSDAPRLLEASPIDEVVVTNTIPHEIQKMQCHKIKTI 160

                         170       180
                  ....*....|....*....|....
gi 186700616  356 DISLILSEAIRRIHNGESMAYLFR 379
Cdd:pfam14572 161 DISQLIAEAIRRIHNGESMSYLFR 184
PrsA COG0462
Phosphoribosylpyrophosphate synthetase [Nucleotide transport and metabolism]; ...
 38-379 4.68e-99

Phosphoribosylpyrophosphate synthetase [Nucleotide transport and metabolism]; Phosphoribosylpyrophosphate synthetase is part of the Pathway/BioSystem: Histidine biosynthesis, Purine biosynthesis


Pssm-ID: 440230 [Multi-domain]  Cd Length: 311  Bit Score: 296.59  E-value: 4.68e-99
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 186700616  38 RVFSANSTAactELAKRITERLGAELGKSVVYQETNGETRVEIKESVRGQDIFIIQTIPRDVNTAVMELLIMAYALKTAC 117
Cdd:COG0462    5 KIFSGNANP---ELAEEIAEYLGVPLGKAEVRRFSDGEIYVRIEESVRGRDVFVIQSTSPPVNDNLMELLIMIDALKRAS 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 186700616 118 ARNIIGVIPYFPYSKQ-SKMRKRGSIVCKLLASMLAKAGLTHIITMDLHQKEIQGFFCFPVDNLRASPFLLQYIQEEipN 196
Cdd:COG0462   82 ARRITAVIPYYGYARQdRKFRPREPITAKLVADLLEAAGADRVLTVDLHAPQIQGFFDIPVDHLYAAPLLADYIKSK--D 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 186700616 197 YRNAVIVakSPDA--AKRAQSYAERLRLGLAVIHGEaqcteldmddgRHSPpmvKNATVHpglelplmmakekppiTVVG 274
Cdd:COG0462  160 LEDLVVV--SPDVggVKRARAFAKRLGAPLAIIDKR-----------RPGA---NEVEVM----------------NIIG 207

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 186700616 275 DVGGRI----------AiivddiiddvESFVAAAETLKERGAYKIYVMATHGILSAEAPRLIEESPIDEVVVTNTVPHEL 344
Cdd:COG0462  208 DVEGKTciivddmidtG----------GTLVEAAEALKEAGAKSVYAAATHGVLSGPAVERLENSPIDELVVTDTIPLPE 277

                        330       340       350
                 ....*....|....*....|....*....|....*
gi 186700616 345 QKlQCPKIKTVDISLILSEAIRRIHNGESMAYLFR 379
Cdd:COG0462  278 EK-RCDKIKVLSVAPLLAEAIRRIHEGESVSSLFD 311
PRK01259 PRK01259
ribose-phosphate diphosphokinase;
37-379 1.26e-90

ribose-phosphate diphosphokinase;


Pssm-ID: 234929 [Multi-domain]  Cd Length: 309  Bit Score: 275.07  E-value: 1.26e-90
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 186700616  37 YRVFSANStaaCTELAKRITERLGAELGKSVVYQETNGETRVEIKESVRGQDIFIIQTIPRDVNTAVMELLIMAYALKTA 116
Cdd:PRK01259   1 MKLFAGNA---NPELAEKIAKYLGIPLGKASVGRFSDGEISVEINENVRGKDVFIIQSTCAPTNDNLMELLIMIDALKRA 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 186700616 117 CARNIIGVIPYFPYSKQS-KMRKRGSIVCKLLASMLAKAGLTHIITMDLHQKEIQGFFCFPVDNLRASPFLLQYIQEEip 195
Cdd:PRK01259  78 SAGRITAVIPYFGYARQDrKARSRVPITAKLVANLLETAGADRVLTMDLHADQIQGFFDIPVDNLYGSPILLEDIKQK-- 155

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 186700616 196 NYRNAVIVakSPD--AAKRAQSYAERLRLGLAVIhgeaqcteldmdDGRHSPPMVknATVhpglelplmmakekppITVV 273
Cdd:PRK01259 156 NLENLVVV--SPDvgGVVRARALAKRLDADLAII------------DKRRPRANV--SEV----------------MNII 203

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 186700616 274 GDVGGRIAIIVDDIIDDVESFVAAAETLKERGAYKIYVMATHGILSAEAPRLIEESPIDEVVVTNTVPHELQKLQCPKIK 353
Cdd:PRK01259 204 GDVEGRDCILVDDMIDTAGTLCKAAEALKERGAKSVYAYATHPVLSGGAIERIENSVIDELVVTDSIPLSEEAKKCDKIR 283

                        330       340
                 ....*....|....*....|....*.
gi 186700616 354 TVDISLILSEAIRRIHNGESMAYLFR 379
Cdd:PRK01259 284 VLSVAPLLAEAIRRISNEESVSSLFD 309
ribP_PPkin TIGR01251
ribose-phosphate pyrophosphokinase; Alternate name: phosphoribosylpyrophosphate synthetase In ...
 37-379 1.94e-87

ribose-phosphate pyrophosphokinase; Alternate name: phosphoribosylpyrophosphate synthetase In some systems, close homologs lacking enzymatic activity exist and perform regulatory functions. The model is designated subfamily rather than equivalog for this reason. [Purines, pyrimidines, nucleosides, and nucleotides, Purine ribonucleotide biosynthesis]


Pssm-ID: 273523 [Multi-domain]  Cd Length: 308  Bit Score: 266.84  E-value: 1.94e-87
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 186700616   37 YRVFSANSTAactELAKRITERLGAELGKSVVYQETNGETRVEIKESVRGQDIFII-QTIPRDVNTAVMELLIMAYALKT 115
Cdd:TIGR01251   1 MKIFSGSSNQ---ELAQKVAKNLGLPLGDVEVKRFPDGELYVRINESVRGKDVFIIqQSTSAPVNDNLMELLIMIDALKR 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 186700616  116 ACARNIIGVIPYFPYSKQSKMRKRG-SIVCKLLASMLAKAGLTHIITMDLHQKEIQGFFCFPVDNLRASPFLLQYIQEEI 194
Cdd:TIGR01251  78 ASAKSITAVIPYYGYARQDKKFKSRePISAKLVANLLETAGADRVLTVDLHSPQIQGFFDVPVDNLYASPVLAEYLKKKI 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 186700616  195 PNyrNAVIVakSPD--AAKRAQSYAERLRLGLAVIHGEaqcteldmddgRHSPPmvKNATVHPglelplmmakekppitV 272
Cdd:TIGR01251 158 LD--NPVVV--SPDagGVERAKKVADALGCPLAIIDKR-----------RISAT--NEVEVMN----------------L 204

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 186700616  273 VGDVGGRIAIIVDDIIDDVESFVAAAETLKERGAYKIYVMATHGILSAEAPRLIEESPIDEVVVTNTVPHElqkLQCPKI 352
Cdd:TIGR01251 205 VGDVEGKDVVIVDDIIDTGGTIAKAAEILKSAGAKRVIAAATHGVFSGPAIERIANAGVEEVIVTNTIPHE---KHKPKV 281

                         330       340
                  ....*....|....*....|....*..
gi 186700616  353 KTVDISLILSEAIRRIHNGESMAYLFR 379
Cdd:TIGR01251 282 SVISVAPLIAEAIRRIHNNESVSSLFD 308
Pribosyltran_N pfam13793
N-terminal domain of ribose phosphate pyrophosphokinase; This family is frequently found ...
 38-155 1.48e-48

N-terminal domain of ribose phosphate pyrophosphokinase; This family is frequently found N-terminal to the Pribosyltran, pfam00156.


Pssm-ID: 433483 [Multi-domain]  Cd Length: 117  Bit Score: 160.28  E-value: 1.48e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 186700616   38 RVFSANStaaCTELAKRITERLGAELGKSVVYQETNGETRVEIKESVRGQDIFIIQTIPRDVNTAVMELLIMAYALKTAC 117
Cdd:pfam13793   2 KIFSGNS---NPELAEKIAKRLGIPLGKATVSRFSDGEIYVRIEESVRGKDVFIIQSTCPPVNDNLMELLIMIDALKRAS 78

                          90       100       110
                  ....*....|....*....|....*....|....*....
gi 186700616  118 ARNIIGVIPYFPYSKQSKM-RKRGSIVCKLLASMLAKAG 155
Cdd:pfam13793  79 AKRITAVIPYFGYARQDRKdKPREPITAKLVADLLEAAG 117
 
Name Accession Description Interval E-value
Pribosyl_synth pfam14572
Phosphoribosyl synthetase-associated domain; This family includes several examples of enzymes ...
 196-379 4.49e-107

Phosphoribosyl synthetase-associated domain; This family includes several examples of enzymes from class EC:2.7.6.1, phosphoribosyl-pyrophosphate transferase.


Pssm-ID: 434046  Cd Length: 184  Bit Score: 312.52  E-value: 4.49e-107
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 186700616  196 NYRNAVIVAKSPDAAKRAQSYAERLRLGLAVIHGEAQCTELDMDDGRHSPPMVKNATVHPGLELPLMMAKEKPPITVVGD 275
Cdd:pfam14572   1 DYRNAVIVARSPGSAKRATSFAERLRLGIAVIHGEQKEAESDEVDGRQSPPPYRSRTVSRSLGLPEIIPKEKPPMTVVGD 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 186700616  276 VGGRIAIIVDDIIDDVESFVAAAETLKERGAYKIYVMATHGILSAEAPRLIEESPIDEVVVTNTVPHELQKLQCPKIKTV 355
Cdd:pfam14572  81 VGGRIAIIVDDMIDDVDSFVAAAELLKERGAYKIYVMATHGLLSSDAPRLLEASPIDEVVVTNTIPHEIQKMQCHKIKTI 160

                         170       180
                  ....*....|....*....|....
gi 186700616  356 DISLILSEAIRRIHNGESMAYLFR 379
Cdd:pfam14572 161 DISQLIAEAIRRIHNGESMSYLFR 184
PrsA COG0462
Phosphoribosylpyrophosphate synthetase [Nucleotide transport and metabolism]; ...
 38-379 4.68e-99

Phosphoribosylpyrophosphate synthetase [Nucleotide transport and metabolism]; Phosphoribosylpyrophosphate synthetase is part of the Pathway/BioSystem: Histidine biosynthesis, Purine biosynthesis


Pssm-ID: 440230 [Multi-domain]  Cd Length: 311  Bit Score: 296.59  E-value: 4.68e-99
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 186700616  38 RVFSANSTAactELAKRITERLGAELGKSVVYQETNGETRVEIKESVRGQDIFIIQTIPRDVNTAVMELLIMAYALKTAC 117
Cdd:COG0462    5 KIFSGNANP---ELAEEIAEYLGVPLGKAEVRRFSDGEIYVRIEESVRGRDVFVIQSTSPPVNDNLMELLIMIDALKRAS 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 186700616 118 ARNIIGVIPYFPYSKQ-SKMRKRGSIVCKLLASMLAKAGLTHIITMDLHQKEIQGFFCFPVDNLRASPFLLQYIQEEipN 196
Cdd:COG0462   82 ARRITAVIPYYGYARQdRKFRPREPITAKLVADLLEAAGADRVLTVDLHAPQIQGFFDIPVDHLYAAPLLADYIKSK--D 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 186700616 197 YRNAVIVakSPDA--AKRAQSYAERLRLGLAVIHGEaqcteldmddgRHSPpmvKNATVHpglelplmmakekppiTVVG 274
Cdd:COG0462  160 LEDLVVV--SPDVggVKRARAFAKRLGAPLAIIDKR-----------RPGA---NEVEVM----------------NIIG 207

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 186700616 275 DVGGRI----------AiivddiiddvESFVAAAETLKERGAYKIYVMATHGILSAEAPRLIEESPIDEVVVTNTVPHEL 344
Cdd:COG0462  208 DVEGKTciivddmidtG----------GTLVEAAEALKEAGAKSVYAAATHGVLSGPAVERLENSPIDELVVTDTIPLPE 277

                        330       340       350
                 ....*....|....*....|....*....|....*
gi 186700616 345 QKlQCPKIKTVDISLILSEAIRRIHNGESMAYLFR 379
Cdd:COG0462  278 EK-RCDKIKVLSVAPLLAEAIRRIHEGESVSSLFD 311
PRK01259 PRK01259
ribose-phosphate diphosphokinase;
37-379 1.26e-90

ribose-phosphate diphosphokinase;


Pssm-ID: 234929 [Multi-domain]  Cd Length: 309  Bit Score: 275.07  E-value: 1.26e-90
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 186700616  37 YRVFSANStaaCTELAKRITERLGAELGKSVVYQETNGETRVEIKESVRGQDIFIIQTIPRDVNTAVMELLIMAYALKTA 116
Cdd:PRK01259   1 MKLFAGNA---NPELAEKIAKYLGIPLGKASVGRFSDGEISVEINENVRGKDVFIIQSTCAPTNDNLMELLIMIDALKRA 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 186700616 117 CARNIIGVIPYFPYSKQS-KMRKRGSIVCKLLASMLAKAGLTHIITMDLHQKEIQGFFCFPVDNLRASPFLLQYIQEEip 195
Cdd:PRK01259  78 SAGRITAVIPYFGYARQDrKARSRVPITAKLVANLLETAGADRVLTMDLHADQIQGFFDIPVDNLYGSPILLEDIKQK-- 155

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 186700616 196 NYRNAVIVakSPD--AAKRAQSYAERLRLGLAVIhgeaqcteldmdDGRHSPPMVknATVhpglelplmmakekppITVV 273
Cdd:PRK01259 156 NLENLVVV--SPDvgGVVRARALAKRLDADLAII------------DKRRPRANV--SEV----------------MNII 203

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 186700616 274 GDVGGRIAIIVDDIIDDVESFVAAAETLKERGAYKIYVMATHGILSAEAPRLIEESPIDEVVVTNTVPHELQKLQCPKIK 353
Cdd:PRK01259 204 GDVEGRDCILVDDMIDTAGTLCKAAEALKERGAKSVYAYATHPVLSGGAIERIENSVIDELVVTDSIPLSEEAKKCDKIR 283

                        330       340
                 ....*....|....*....|....*.
gi 186700616 354 TVDISLILSEAIRRIHNGESMAYLFR 379
Cdd:PRK01259 284 VLSVAPLLAEAIRRISNEESVSSLFD 309
ribP_PPkin TIGR01251
ribose-phosphate pyrophosphokinase; Alternate name: phosphoribosylpyrophosphate synthetase In ...
 37-379 1.94e-87

ribose-phosphate pyrophosphokinase; Alternate name: phosphoribosylpyrophosphate synthetase In some systems, close homologs lacking enzymatic activity exist and perform regulatory functions. The model is designated subfamily rather than equivalog for this reason. [Purines, pyrimidines, nucleosides, and nucleotides, Purine ribonucleotide biosynthesis]


Pssm-ID: 273523 [Multi-domain]  Cd Length: 308  Bit Score: 266.84  E-value: 1.94e-87
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 186700616   37 YRVFSANSTAactELAKRITERLGAELGKSVVYQETNGETRVEIKESVRGQDIFII-QTIPRDVNTAVMELLIMAYALKT 115
Cdd:TIGR01251   1 MKIFSGSSNQ---ELAQKVAKNLGLPLGDVEVKRFPDGELYVRINESVRGKDVFIIqQSTSAPVNDNLMELLIMIDALKR 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 186700616  116 ACARNIIGVIPYFPYSKQSKMRKRG-SIVCKLLASMLAKAGLTHIITMDLHQKEIQGFFCFPVDNLRASPFLLQYIQEEI 194
Cdd:TIGR01251  78 ASAKSITAVIPYYGYARQDKKFKSRePISAKLVANLLETAGADRVLTVDLHSPQIQGFFDVPVDNLYASPVLAEYLKKKI 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 186700616  195 PNyrNAVIVakSPD--AAKRAQSYAERLRLGLAVIHGEaqcteldmddgRHSPPmvKNATVHPglelplmmakekppitV 272
Cdd:TIGR01251 158 LD--NPVVV--SPDagGVERAKKVADALGCPLAIIDKR-----------RISAT--NEVEVMN----------------L 204

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 186700616  273 VGDVGGRIAIIVDDIIDDVESFVAAAETLKERGAYKIYVMATHGILSAEAPRLIEESPIDEVVVTNTVPHElqkLQCPKI 352
Cdd:TIGR01251 205 VGDVEGKDVVIVDDIIDTGGTIAKAAEILKSAGAKRVIAAATHGVFSGPAIERIANAGVEEVIVTNTIPHE---KHKPKV 281

                         330       340
                  ....*....|....*....|....*..
gi 186700616  353 KTVDISLILSEAIRRIHNGESMAYLFR 379
Cdd:TIGR01251 282 SVISVAPLIAEAIRRIHNNESVSSLFD 308
PRK03092 PRK03092
ribose-phosphate diphosphokinase;
51-378 9.76e-67

ribose-phosphate diphosphokinase;


Pssm-ID: 179535 [Multi-domain]  Cd Length: 304  Bit Score: 213.66  E-value: 9.76e-67
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 186700616  51 LAKRITERLGAELGKSVVYQETNGETRVEIKESVRGQDIFIIQTIPRDVNTAVMELLIMAYALKTACARNIIGVIPYFPY 130
Cdd:PRK03092   1 LAEEVAKELGVEVTPTTAYDFANGEIYVRFEESVRGCDAFVLQSHTAPINKWLMEQLIMIDALKRASAKRITVVLPFYPY 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 186700616 131 SKQSKM-RKRGSIVCKLLASMLAKAGLTHIITMDLHQKEIQGFFCFPVDNLRASPFLLQYIQEEIPNyRNAVIVakSPDA 209
Cdd:PRK03092  81 ARQDKKhRGREPISARLVADLFKTAGADRIMTVDLHTAQIQGFFDGPVDHLFAMPLLADYVRDKYDL-DNVTVV--SPDA 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 186700616 210 A--KRAQSYAERL-RLGLAVIHgeaqcteldmddGRHSPPMVKNATVHpglelplmmakekppiTVVGDVGGRIAIIVDD 286
Cdd:PRK03092 158 GrvRVAEQWADRLgGAPLAFIH------------KTRDPTVPNQVVAN----------------RVVGDVEGRTCVLVDD 209

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 186700616 287 IIDDVESFVAAAETLKERGAYKIYVMATHGILSAEAPRLIEESPIDEVVVTNTVPHELQKlQCPKIKTVDISLILSEAIR 366
Cdd:PRK03092 210 MIDTGGTIAGAVRALKEAGAKDVIIAATHGVLSGPAAERLKNCGAREVVVTDTLPIPEEK-RFDKLTVLSIAPLLARAIR 288

                        330
                 ....*....|..
gi 186700616 367 RIHNGESMAYLF 378
Cdd:PRK03092 289 EVFEDGSVTSLF 300
PRK02269 PRK02269
ribose-phosphate diphosphokinase;
38-378 2.04e-65

ribose-phosphate diphosphokinase;


Pssm-ID: 167353 [Multi-domain]  Cd Length: 320  Bit Score: 210.80  E-value: 2.04e-65
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 186700616  38 RVFSANSTaacTELAKRITERLGAELGKSVVYQETNGETRVEIKESVRGQDIFIIQTIPRDVNTAVMELLIMAYALKTAC 117
Cdd:PRK02269   7 KLFALSSN---KELAEKVAQEIGIELGKSSVRQFSDGEIQVNIEESIRGHHVFILQSTSSPVNDNLMEILIMVDALKRAS 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 186700616 118 ARNIIGVIPYFPYSKQS-KMRKRGSIVCKLLASMLAKAGLTHIITMDLHQKEIQGFFCFPVDNLRASPFLLQYIQEEIPN 196
Cdd:PRK02269  84 AESINVVMPYYGYARQDrKARSREPITSKLVANMLEVAGVDRLLTVDLHAAQIQGFFDIPVDHLMGAPLIADYFDRRGLV 163

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 186700616 197 YRNAVIVakSPDAA--KRAQSYAERLRLGLAVIhgeaqcteldmdDGRHSPPMVKNATVhpglelplmmakekppITVVG 274
Cdd:PRK02269 164 GDDVVVV--SPDHGgvTRARKLAQFLKTPIAII------------DKRRSVDKMNTSEV----------------MNIIG 213

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 186700616 275 DVGGRIAIIVDDIIDDVESFVAAAETLKERGAYKIYVMATHGILSAEAPRLIEESPIDEVVVTNTVPHELQKLqCPKIKT 354
Cdd:PRK02269 214 NVKGKKCILIDDMIDTAGTICHAADALAEAGATEVYASCTHPVLSGPALDNIQKSAIEKLVVLDTIYLPEERL-IDKIEQ 292

                        330       340
                 ....*....|....*....|....
gi 186700616 355 VDISLILSEAIRRIHNGESMAYLF 378
Cdd:PRK02269 293 ISIADLLGEAIIRIHEKRPLSPLF 316
PRK04923 PRK04923
ribose-phosphate diphosphokinase;
39-378 1.50e-64

ribose-phosphate diphosphokinase;


Pssm-ID: 179893 [Multi-domain]  Cd Length: 319  Bit Score: 208.63  E-value: 1.50e-64
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 186700616  39 VFSANstaACTELAKRITERLGAELGKSVVYQETNGETRVEIKESVRGQDIFIIQTIPRDVNTAVMELLIMAYALKTACA 118
Cdd:PRK04923   9 VFSGN---ANKPLAQSICKELGVRMGKALVTRFSDGEVQVEIEESVRRQEVFVIQPTCAPSAENLMELLVLIDALKRASA 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 186700616 119 RNIIGVIPYFPYSKQSK-MRK-RGSIVCKLLASMLAKAGLTHIITMDLHQKEIQGFFCFPVDNLRASPFLLQYIQEEIpN 196
Cdd:PRK04923  86 ASVTAVIPYFGYSRQDRrMRSsRVPITAKVAAKMISAMGADRVLTVDLHADQIQGFFDVPVDNVYASPLLLADIWRAY-G 164

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 186700616 197 YRNAVIVAKSPDAAKRAQSYAERL-RLGLAVIhgeaqcteldmdDGRHspPMVKNATVhpglelplmmakekppITVVGD 275
Cdd:PRK04923 165 TDNLIVVSPDVGGVVRARAVAKRLdDADLAII------------DKRR--PRANVATV----------------MNIIGD 214

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 186700616 276 VGGRIAIIVDDIIDDVESFVAAAETLKERGAYKIYVMATHGILSAEAPRLIEESPIDEVVVTNTVPHELQKLQCPKIKTV 355
Cdd:PRK04923 215 VQGKTCVLVDDLVDTAGTLCAAAAALKQRGALKVVAYITHPVLSGPAVDNINNSQLDELVVTDTIPLSEAARACAKIRQL 294

                        330       340
                 ....*....|....*....|...
gi 186700616 356 DISLILSEAIRRIHNGESMAYLF 378
Cdd:PRK04923 295 SVAELLAETIRRIAFGESVSSLY 317
PLN02369 PLN02369
ribose-phosphate pyrophosphokinase
 50-379 6.91e-64

ribose-phosphate pyrophosphokinase


Pssm-ID: 215209 [Multi-domain]  Cd Length: 302  Bit Score: 206.08  E-value: 6.91e-64
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 186700616  50 ELAKRITERLGAELGKSVVYQETNGETRVEIKESVRGQDIFIIQTIPRDVNTAVMELLIMAYALKTACARNIIGVIPYFP 129
Cdd:PLN02369   2 ALSQEIACYLGLELGKITIKRFADGEIYVQLQESVRGCDVFLVQPTCPPANENLMELLIMIDACRRASAKRITAVIPYFG 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 186700616 130 YSKQS-KMRKRGSIVCKLLASMLAKAGLTHIITMDLHQKEIQGFFCFPVDNLRASPFLLQYIQEEIPNYRNAVIVakSPD 208
Cdd:PLN02369  82 YARADrKTQGRESIAAKLVANLITEAGADRVLACDLHSGQSMGYFDIPVDHVYGQPVILDYLASKTISSPDLVVV--SPD 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 186700616 209 AAK--RAQSYAERLR-LGLAVIhgeaqcteldmDDGRHSPPMVKnatvhpglelplmmakekpPITVVGDVGGRIAIIVD 285
Cdd:PLN02369 160 VGGvaRARAFAKKLSdAPLAIV-----------DKRRQGHNVAE-------------------VMNLIGDVKGKVAIMVD 209

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 186700616 286 DIIDDVESFVAAAETLKERGAYKIYVMATHGILSAEAPRLIEESPIDEVVVTNTVPHELQKlQCPKIKTVDISLILSEAI 365
Cdd:PLN02369 210 DMIDTAGTITKGAALLHQEGAREVYACATHAVFSPPAIERLSSGLFQEVIVTNTIPVSEKN-YFPQLTVLSVANLLGETI 288

                        330
                 ....*....|....
gi 186700616 366 RRIHNGESMAYLFR 379
Cdd:PLN02369 289 WRVHDDCSVSSIFD 302
PRK02458 PRK02458
ribose-phosphate pyrophosphokinase; Provisional
 29-379 3.59e-61

ribose-phosphate pyrophosphokinase; Provisional


Pssm-ID: 235039 [Multi-domain]  Cd Length: 323  Bit Score: 199.97  E-value: 3.59e-61
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 186700616  29 AMNAARTGYRVFSANSTaacTELAKRITERLGAELGKSVVYQETNGETRVEIKESVRGQDIFIIQTIPRDVNTAVMELLI 108
Cdd:PRK02458   2 TERYADKQIKLFSLNSN---LEIAEKIAQAAGVPLGKLSSRQFSDGEIMINIEESVRGDDIYIIQSTSFPVNDHLWELLI 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 186700616 109 MAYALKTACARNIIGVIPYFPYSKQSKMRK-RGSIVCKLLASMLAKAGLTHIITMDLHQKEIQGFFCFPVDNLRASPFLL 187
Cdd:PRK02458  79 MIDACKRASANTVNVVLPYFGYARQDRIAKpREPITAKLVANMLVKAGVDRVLTLDLHAVQVQGFFDIPVDNLFTVPLFA 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 186700616 188 QYIQEEIPNYRNAVIVAKSPDAAKRAQSYAERLRLGLAVIhgeaqctELDMDDGrhsppmvknatvhpglelplmmakEK 267
Cdd:PRK02458 159 KHYCKKGLSGSDVVVVSPKNSGIKRARSLAEYLDAPIAII-------DYAQDDS------------------------ER 207

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 186700616 268 PPITVVGDVGGRIAIIVDDIIDDVESFVAAAETLKERGAYKIYVMATHGILSAEAPRLIEESPIDEVVVTNTVpheLQKL 347
Cdd:PRK02458 208 EEGYIIGDVAGKKAILIDDILNTGKTFAEAAKIVEREGATEIYAVASHGLFAGGAAEVLENAPIKEILVTDSV---ATKE 284

                        330       340       350
                 ....*....|....*....|....*....|...
gi 186700616 348 QCPK-IKTVDISLILSEAIRRIHNGESMAYLFR 379
Cdd:PRK02458 285 RVPKnVTYLSASELIADAIIRIHERKPLSPLFA 317
PRK02812 PRK02812
ribose-phosphate pyrophosphokinase; Provisional
 38-379 4.58e-55

ribose-phosphate pyrophosphokinase; Provisional


Pssm-ID: 235072 [Multi-domain]  Cd Length: 330  Bit Score: 184.18  E-value: 4.58e-55
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 186700616  38 RVFSANSTAActeLAKRITERLGAELGKSVVYQETNGETRVEIKESVRGQDIFIIQTIPRDVNTAVMELLIMAYALKTAC 117
Cdd:PRK02812  23 RLFSGSSNPA---LAQEVARYLGMDLGPMIRKRFADGELYVQIQESIRGCDVYLIQPTCAPVNDHLMELLIMVDACRRAS 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 186700616 118 ARNIIGVIPYFPYSKQS-KMRKRGSIVCKLLASMLAKAGLTHIITMDLHQKEIQGFFCFPVDNLRASPFLLQYIQEEipN 196
Cdd:PRK02812 100 ARQITAVIPYYGYARADrKTAGRESITAKLVANLITKAGADRVLAMDLHSAQIQGYFDIPCDHVYGSPVLLDYLASK--N 177

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 186700616 197 YRNAVIVakSPD--AAKRAQSYAERLRLG-LAVIhgeaqcteldmdDGRHSPPMVKNAtvhpglelplmmakekppITVV 273
Cdd:PRK02812 178 LEDIVVV--SPDvgGVARARAFAKKLNDApLAII------------DKRRQAHNVAEV------------------LNVI 225

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 186700616 274 GDVGGRIAIIVDDIIDDVESFVAAAETLKERGAYKIYVMATHGILSAEAPRLIEESPIDEVVVTNTVPHElQKLQCPKIK 353
Cdd:PRK02812 226 GDVKGKTAILVDDMIDTGGTICEGARLLRKEGAKQVYACATHAVFSPPAIERLSSGLFEEVIVTNTIPVP-EERRFPQLK 304

                        330       340
                 ....*....|....*....|....*.
gi 186700616 354 TVDISLILSEAIRRIHNGESMAYLFR 379
Cdd:PRK02812 305 VLSVANMLGEAIWRIHEESSVSSMFR 330
PTZ00145 PTZ00145
phosphoribosylpyrophosphate synthetase; Provisional
 39-378 9.35e-54

phosphoribosylpyrophosphate synthetase; Provisional


Pssm-ID: 240290 [Multi-domain]  Cd Length: 439  Bit Score: 183.92  E-value: 9.35e-54
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 186700616  39 VFSANSTAActeLAKRITERLGAELGKSVVYQETNGETRVEIKESVRGQDIFIIQTIPRDVNTAVMELLIMAYALKTACA 118
Cdd:PTZ00145 122 LFSGSSNPL---LSKNIADHLGTILGRVHLKRFADGEVSMQFLESIRGKDVYIIQPTCPPVNENLIELLLMISTCRRASA 198

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 186700616 119 RNIIGVIPYFPYSKQS-KMRKRGSIVCKLLASMLAKAGLTHIITMDLHQKEIQGFFC--FPVDNLRASPFLLQYIQEEiP 195
Cdd:PTZ00145 199 KKITAVIPYYGYARQDrKLSSRVPISAADVARMIEAMGVDRVVAIDLHSGQIQGFFGprVPVDNLEAQLIGLDYFTKK-D 277

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 186700616 196 NYRnAVIVakSPDAAK--RAQSYAERLrlglaVIHGEAQCTeLDMddgrhsppMVKNATvhpglelplmMAKEKPPITVV 273
Cdd:PTZ00145 278 LYK-PVIV--SPDAGGvyRARKFQDGL-----NHRGISDCG-IAM--------LIKQRT----------KPNEIEKMDLV 330

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 186700616 274 GDVGGRIAIIVDDIIDDVESFVAAAETLKERGAYKIYVMATHGILSAEAPRLIEESPIDEVVVTNTVPHELQKLQCPKIK 353
Cdd:PTZ00145 331 GNVYDSDVIIVDDMIDTSGTLCEAAKQLKKHGARRVFAFATHGLFSGPAIERIEASPLEEVVVTDTVKSNKNIDSCKKIT 410

                        330       340
                 ....*....|....*....|....*
gi 186700616 354 TVDISLILSEAIRRIHNGESMAYLF 378
Cdd:PTZ00145 411 KLSVSVLVADAIRRIHQKESLNDLF 435
PRK00553 PRK00553
ribose-phosphate pyrophosphokinase; Provisional
 30-378 1.31e-50

ribose-phosphate pyrophosphokinase; Provisional


Pssm-ID: 179062 [Multi-domain]  Cd Length: 332  Bit Score: 172.79  E-value: 1.31e-50
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 186700616  30 MNAARTGYRVFSANSTaacTELAKRITERLGAELGKSVVYQETNGETRVEIKESVRGQDIFIIQTIPRDVNTAVMELLIM 109
Cdd:PRK00553   3 LSIDKSNHVIFSLSKA---KKLVDSICRKLSMKPGEIVIQKFADGETYIRFDESVRNKDVVIFQSTCSPVNDSLMELLIA 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 186700616 110 AYALKTACARNIIGVIPYFPYSKQS-KMRKRGSIVCKLLASMLAKAGLTHIITMDLHQKEIQGFFCFPVDNLRASPFLLQ 188
Cdd:PRK00553  80 IDALKRGSAKSITAILPYYGYARQDrKTAGREPITSKLVADLLTKAGVTRVTLTDIHSDQTQGFFDIPVDILRTYHVFLS 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 186700616 189 YIQEEIpNYRNAVIVakSPD--AAKRAQSYAERLRLGLAVIhgeaqcteldmdDGRHSPPMVKNAtvhpglelplmmake 266
Cdd:PRK00553 160 RVLELL-GKKDLVVV--SPDygGVKRARLIAESLELPLAII------------DKRRPKHNVAES--------------- 209

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 186700616 267 kppITVVGDVGGRIAIIVDDIIDDVESFVAAAETLKERGAYKIYVMATHGILSAEAPRLIEES----PIDEVVVTNTVPH 342
Cdd:PRK00553 210 ---INVLGEVKNKNCLIVDDMIDTGGTVIAAAKLLKKQKAKKVCVMATHGLFNKNAIQLFDEAfkkkLIDKLFVSNSIPQ 286

                        330       340       350
                 ....*....|....*....|....*....|....*.
gi 186700616 343 ELQKlQCPKIKTVDISLILSEAIRRIHNGESMAYLF 378
Cdd:PRK00553 287 TKFE-KKPQFKVVDLAHLYEEVLLCYANGGSISAIY 321
Pribosyltran_N pfam13793
N-terminal domain of ribose phosphate pyrophosphokinase; This family is frequently found ...
 38-155 1.48e-48

N-terminal domain of ribose phosphate pyrophosphokinase; This family is frequently found N-terminal to the Pribosyltran, pfam00156.


Pssm-ID: 433483 [Multi-domain]  Cd Length: 117  Bit Score: 160.28  E-value: 1.48e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 186700616   38 RVFSANStaaCTELAKRITERLGAELGKSVVYQETNGETRVEIKESVRGQDIFIIQTIPRDVNTAVMELLIMAYALKTAC 117
Cdd:pfam13793   2 KIFSGNS---NPELAEKIAKRLGIPLGKATVSRFSDGEIYVRIEESVRGKDVFIIQSTCPPVNDNLMELLIMIDALKRAS 78

                          90       100       110
                  ....*....|....*....|....*....|....*....
gi 186700616  118 ARNIIGVIPYFPYSKQSKM-RKRGSIVCKLLASMLAKAG 155
Cdd:pfam13793  79 AKRITAVIPYFGYARQDRKdKPREPITAKLVADLLEAAG 117
PRK00934 PRK00934
ribose-phosphate pyrophosphokinase; Provisional
 51-347 3.69e-35

ribose-phosphate pyrophosphokinase; Provisional


Pssm-ID: 234868 [Multi-domain]  Cd Length: 285  Bit Score: 130.42  E-value: 3.69e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 186700616  51 LAKRITERLGAELgksvVYQETN----GETRVEIKESVRGQDIFIIQTIPRDvNTAVMELLIMAYALKTACARNIIGVIP 126
Cdd:PRK00934  11 LASEVARLLNTEL----ALVETKrfpdGELYVRILGEIDGEDVVIISTTYPQ-DENLVELLLLIDALRDEGAKSITLVIP 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 186700616 127 YFPYSKQSKMRKRG-SIVCKLLASMLAKAGlTHIITMDLHQKEIQGFFCFPVDNLRASPFLLQYIQEEIpnyRNAVIVAk 205
Cdd:PRK00934  86 YLGYARQDKRFKPGePISARAIAKIISAYY-DRIITINIHEPSILEFFPIPFINLDAAPLIAEYIGDKL---DDPLVLA- 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 186700616 206 sPD--AAKRAQSYAERLrlGLAVIHGEAQcteldmddgRHSPPMVKNATVHpglelplMMAKEKPpITVVGDV---GGRI 280
Cdd:PRK00934 161 -PDkgALELAKEAAEIL--GCEYDYLEKT---------RISPTEVEIAPKN-------LDVKGKD-VLIVDDIistGGTM 220

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 186700616 281 AIivddiiddvesfvaAAETLKERGAYKIYVMATHGILSAEAPRLIEESPIDEVVVTNTVPHELQKL 347
Cdd:PRK00934 221 AT--------------AIKILKEQGAKKVYVACVHPVLVGDAILKLYNAGVDEIIVTDTLESEVSKI 273
PRK06827 PRK06827
phosphoribosylpyrophosphate synthetase; Provisional
 73-380 3.58e-31

phosphoribosylpyrophosphate synthetase; Provisional


Pssm-ID: 180714 [Multi-domain]  Cd Length: 382  Bit Score: 121.98  E-value: 3.58e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 186700616  73 NGETRVEIKESVRGQDIFIIQ--------------TIPRDVNTAVMEL--LIMAYALKtacARNIIGVIPYFPYSKQSKM 136
Cdd:PRK06827  64 NGEAKGEILESVRGKDIYILQdvgnysvtynmfgeKNHMSPDDHFQDLkrTIDAIRGK---ARRITVIMPFLYESRQHKR 140

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 186700616 137 RKRGSIVCKLLASMLAKAGLTHIITMDLHQKEIQGFF-CFPVDNLRASPFLLQYIQEEIPNYR----NAVIVakSPD--A 209
Cdd:PRK06827 141 KGRESLDCALALQELEELGVDNIITFDAHDPRIENAIpLMGFENLYPSYQIIKALLKNEKDLEidkdHLMVI--SPDtgA 218

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 186700616 210 AKRAQSYAERLRLGLAVIHGEaqcteldmddgRHSPPMVKNatvhpglelplmmakeKPPITVV----GDVGGRIAIIVD 285
Cdd:PRK06827 219 MDRAKYYASVLGVDLGLFYKR-----------RDYSRVVNG----------------RNPIVAHeflgRDVEGKDVLIVD 271

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 186700616 286 DIIDDVESFVAAAETLKERGAYKIYVMATHGiLSAEAPRLI----EESPIDEVVVTNTVPHELQKLQCPKIKTVDISLIL 361
Cdd:PRK06827 272 DMIASGGSMIDAAKELKSRGAKKIIVAATFG-FFTNGLEKFdkayEEGYFDRIIGTNLVYHPEELLSKPWYIEVDMSKLI 350

                        330
                 ....*....|....*....
gi 186700616 362 SEAIRRIHNGESMAYLFRN 380
Cdd:PRK06827 351 ARIIDALNHDVSLSKLLDP 369
PRK07199 PRK07199
ribose-phosphate diphosphokinase;
48-367 1.21e-13

ribose-phosphate diphosphokinase;


Pssm-ID: 235960 [Multi-domain]  Cd Length: 301  Bit Score: 70.74  E-value: 1.21e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 186700616  48 CTELAKRITERLGAELGKSVVYQETNGETRVEIKESVRGQDIFIIQTIPRDvNTAVMELLIMAYALKTACARNIIGVIPY 127
Cdd:PRK07199  11 NEAAAGRLAAALGVEVGRIELHRFPDGESYVRLDSPVAGRTVVLVCSLDRP-DEKLLPLLFAAEAARELGARRVGLVAPY 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 186700616 128 FPYSKQSKMRKRGSIVC-KLLASMLAkAGLTHIITMD--LHQ-KEIQGFFCFPVDNLRASPFLLQYIQEEIPnyrNAVIV 203
Cdd:PRK07199  90 LAYMRQDIAFHPGEAISqRHFARLLS-GSFDRLVTVDphLHRyPSLSEVYPIPAVVLSAAPAIAAWIRAHVP---RPLLI 165

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 186700616 204 AksPDAAKR--AQSYAERLRLGLAVihgeaqCTELdmddgRHSPPMVK----NATVHPGlelplmmakeKPPItVVGDV- 276
Cdd:PRK07199 166 G--PDEESEqwVAAVAERAGAPHAV------LRKT-----RHGDRDVEislpDAAPWAG----------RTPV-LVDDIv 221

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 186700616 277 -GGRiaiivddiiddveSFVAAAETLKERGAYKIYVMATHGILSAEAPRLIEESPIDEVVVTNTVPHElqklqcpkIKTV 355
Cdd:PRK07199 222 sTGR-------------TLIEAARQLRAAGAASPDCVVVHALFAGDAYSALAAAGIARVVSTDTVPHP--------SNAI 280

                        330
                 ....*....|..
gi 186700616 356 DISLILSEAIRR 367
Cdd:PRK07199 281 SLAPLLAEALRR 292
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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