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Conserved domains on  [gi|187608312|ref|NP_775749|]
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cyclin N-terminal domain-containing protein 1 isoform 1 [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
CYCLIN_CNTD1 cd20541
cyclin box found in Cyclin N-terminal domain-containing protein 1 (CNTD1) and similar proteins; ...
 50-177 1.90e-50

cyclin box found in Cyclin N-terminal domain-containing protein 1 (CNTD1) and similar proteins; CNTD1 is a cyclin-related protein critical for meiotic crossover maturation and deselection of excess precrossover sites. CNTD1 contains one cyclin box. The cyclin box is a protein binding domain.


:

Pssm-ID: 410244  Cd Length: 127  Bit Score: 163.92  E-value: 1.90e-50
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187608312  50 FREPQIVEFVFLLSEQWCLEKSVSYQAVEILERFMVKQAENICRQATIQPRdNKRESQNWRALKQQLVNKFTLRLVSCVQ 129
Cdd:cd20541    1 FKTGRLVEFVFLLCEKLGLPPEVKYLAVELFDRFMSRHIEELYKSVRESNK-IKGKKEEWKEVESRLSKQLPLRLVSCVQ 79

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*...
gi 187608312 130 LASKLSFRNKIISNITVLNFLQALGYLHTKEELLESELDVLKSLNFRI 177
Cdd:cd20541   80 LASKLSSHYKIVSANKAKNFLQSLGHPYTKSSILKSELRVLKTLNFRV 127
 
Name Accession Description Interval E-value
CYCLIN_CNTD1 cd20541
cyclin box found in Cyclin N-terminal domain-containing protein 1 (CNTD1) and similar proteins; ...
 50-177 1.90e-50

cyclin box found in Cyclin N-terminal domain-containing protein 1 (CNTD1) and similar proteins; CNTD1 is a cyclin-related protein critical for meiotic crossover maturation and deselection of excess precrossover sites. CNTD1 contains one cyclin box. The cyclin box is a protein binding domain.


Pssm-ID: 410244  Cd Length: 127  Bit Score: 163.92  E-value: 1.90e-50
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187608312  50 FREPQIVEFVFLLSEQWCLEKSVSYQAVEILERFMVKQAENICRQATIQPRdNKRESQNWRALKQQLVNKFTLRLVSCVQ 129
Cdd:cd20541    1 FKTGRLVEFVFLLCEKLGLPPEVKYLAVELFDRFMSRHIEELYKSVRESNK-IKGKKEEWKEVESRLSKQLPLRLVSCVQ 79

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*...
gi 187608312 130 LASKLSFRNKIISNITVLNFLQALGYLHTKEELLESELDVLKSLNFRI 177
Cdd:cd20541   80 LASKLSSHYKIVSANKAKNFLQSLGHPYTKSSILKSELRVLKTLNFRV 127
 
Name Accession Description Interval E-value
CYCLIN_CNTD1 cd20541
cyclin box found in Cyclin N-terminal domain-containing protein 1 (CNTD1) and similar proteins; ...
 50-177 1.90e-50

cyclin box found in Cyclin N-terminal domain-containing protein 1 (CNTD1) and similar proteins; CNTD1 is a cyclin-related protein critical for meiotic crossover maturation and deselection of excess precrossover sites. CNTD1 contains one cyclin box. The cyclin box is a protein binding domain.


Pssm-ID: 410244  Cd Length: 127  Bit Score: 163.92  E-value: 1.90e-50
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187608312  50 FREPQIVEFVFLLSEQWCLEKSVSYQAVEILERFMVKQAENICRQATIQPRdNKRESQNWRALKQQLVNKFTLRLVSCVQ 129
Cdd:cd20541    1 FKTGRLVEFVFLLCEKLGLPPEVKYLAVELFDRFMSRHIEELYKSVRESNK-IKGKKEEWKEVESRLSKQLPLRLVSCVQ 79

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*...
gi 187608312 130 LASKLSFRNKIISNITVLNFLQALGYLHTKEELLESELDVLKSLNFRI 177
Cdd:cd20541   80 LASKLSSHYKIVSANKAKNFLQSLGHPYTKSSILKSELRVLKTLNFRV 127
CYCLIN_CCNJ-like_rpt1 cd20528
first cyclin box found in cyclin-J (CCNJ) family; The CCNJ family includes two cyclins, CCNJ ...
 53-175 5.37e-03

first cyclin box found in cyclin-J (CCNJ) family; The CCNJ family includes two cyclins, CCNJ and CCNJ-like. CCNJ may regulate the cell cycle or transcription. Members of this family contain two cyclin boxes. This model corresponds to the first one. The cyclin box is a protein binding domain.


Pssm-ID: 410231 [Multi-domain]  Cd Length: 103  Bit Score: 36.04  E-value: 5.37e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187608312  53 PQIVEFVFLLSEQWCLEKSVSYQAVEILERFMvkqaenicRQATIQPRdnkresqnwralkqqlvnkfTLRLV--SCVQL 130
Cdd:cd20528    8 RYLVDWLAVVSERLKLSDTTLHLAVYLLDRFM--------DRYDISED--------------------QLHLValTCLLL 59

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*.
gi 187608312 131 ASKLSFRNKIISNITVLN-FLQALGYlhTKEELLESELDVLKSLNF 175
Cdd:cd20528   60 AAKFEELDDNIPKISDLNrYLCNSVY--SKQEYLQMELLILEFFQW 103
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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