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Conserved domains on  [gi|1173909449|gb|OQR74492|]
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39S ribosomal protein L44 [Tropilaelaps mercedesae]

Protein Classification

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
DSRM_MRPL44 cd19874
double-stranded RNA binding motif of mitochondrial 39S ribosomal protein L44 (MRPL44) and ...
199-282 4.33e-37

double-stranded RNA binding motif of mitochondrial 39S ribosomal protein L44 (MRPL44) and similar proteins; MRPL44 (also known as L44mt, MRP-L44, or mitochondrial large ribosomal subunit protein mL44) is a component of the 39S subunit of mitochondrial ribosome. It may play a role in the assembly/stability of nascent mitochondrial polypeptides exiting the ribosome. MRPL44 contains a RNase III-like domain and a double-stranded RNA binding motif (DSRM). DSRM is not sequence specific, but highly specific for dsRNAs of various origin and structure.


:

Pssm-ID: 380703  Cd Length: 84  Bit Score: 127.71  E-value: 4.33e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1173909449 199 CGKDVFDLWNPKDVTHMLNTLLQQQKLPPYEARLIGETGRNTLESLFYVGVYAGGKQLGKGAGSTQAQALDVAVRDALRR 278
Cdd:cd19874     1 VGKDLNEIWTPANPMGLLVEILQKRGLPPPEPRLIRQSGANTVLPVYFVGLYSDKKLIGEGPGESILIAEEMAARDALRR 80

                  ....
gi 1173909449 279 AFGV 282
Cdd:cd19874    81 LFGT 84
 
Name Accession Description Interval E-value
DSRM_MRPL44 cd19874
double-stranded RNA binding motif of mitochondrial 39S ribosomal protein L44 (MRPL44) and ...
199-282 4.33e-37

double-stranded RNA binding motif of mitochondrial 39S ribosomal protein L44 (MRPL44) and similar proteins; MRPL44 (also known as L44mt, MRP-L44, or mitochondrial large ribosomal subunit protein mL44) is a component of the 39S subunit of mitochondrial ribosome. It may play a role in the assembly/stability of nascent mitochondrial polypeptides exiting the ribosome. MRPL44 contains a RNase III-like domain and a double-stranded RNA binding motif (DSRM). DSRM is not sequence specific, but highly specific for dsRNAs of various origin and structure.


Pssm-ID: 380703  Cd Length: 84  Bit Score: 127.71  E-value: 4.33e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1173909449 199 CGKDVFDLWNPKDVTHMLNTLLQQQKLPPYEARLIGETGRNTLESLFYVGVYAGGKQLGKGAGSTQAQALDVAVRDALRR 278
Cdd:cd19874     1 VGKDLNEIWTPANPMGLLVEILQKRGLPPPEPRLIRQSGANTVLPVYFVGLYSDKKLIGEGPGESILIAEEMAARDALRR 80

                  ....
gi 1173909449 279 AFGV 282
Cdd:cd19874    81 LFGT 84
DSRM smart00358
Double-stranded RNA binding motif;
216-277 9.64e-04

Double-stranded RNA binding motif;


Pssm-ID: 214634 [Multi-domain]  Cd Length: 67  Bit Score: 37.24  E-value: 9.64e-04
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1173909449  216 LNTLLQQQKLPP-YEarLIGETGrNTLESLFYVGVYAGGKQLGKGAGSTQAQALDVAVRDALR 277
Cdd:smart00358   5 LQELAQKRKLPPeYE--LVKEEG-PDHAPRFTVTVKVGGKRTGEGEGSSKKEAKQRAAEAALR 64
 
Name Accession Description Interval E-value
DSRM_MRPL44 cd19874
double-stranded RNA binding motif of mitochondrial 39S ribosomal protein L44 (MRPL44) and ...
199-282 4.33e-37

double-stranded RNA binding motif of mitochondrial 39S ribosomal protein L44 (MRPL44) and similar proteins; MRPL44 (also known as L44mt, MRP-L44, or mitochondrial large ribosomal subunit protein mL44) is a component of the 39S subunit of mitochondrial ribosome. It may play a role in the assembly/stability of nascent mitochondrial polypeptides exiting the ribosome. MRPL44 contains a RNase III-like domain and a double-stranded RNA binding motif (DSRM). DSRM is not sequence specific, but highly specific for dsRNAs of various origin and structure.


Pssm-ID: 380703  Cd Length: 84  Bit Score: 127.71  E-value: 4.33e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1173909449 199 CGKDVFDLWNPKDVTHMLNTLLQQQKLPPYEARLIGETGRNTLESLFYVGVYAGGKQLGKGAGSTQAQALDVAVRDALRR 278
Cdd:cd19874     1 VGKDLNEIWTPANPMGLLVEILQKRGLPPPEPRLIRQSGANTVLPVYFVGLYSDKKLIGEGPGESILIAEEMAARDALRR 80

                  ....
gi 1173909449 279 AFGV 282
Cdd:cd19874    81 LFGT 84
DSRM_MRPL3_like cd19873
double-stranded RNA binding motif of Saccharomyces cerevisiae mitochondrial 54S ribosomal ...
201-281 5.20e-15

double-stranded RNA binding motif of Saccharomyces cerevisiae mitochondrial 54S ribosomal protein L3 (MRPL3) and similar proteins; MRPL3 (also called mitochondrial large ribosomal subunit protein mL44) is a component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain. MRPL3 contains a RNase III-like domain and a double-stranded RNA binding motif (DSRM). DSRM is not sequence specific, but highly specific for dsRNAs of various origin and structure.


Pssm-ID: 380702  Cd Length: 84  Bit Score: 69.17  E-value: 5.20e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1173909449 201 KDVFDLWNPKdvtHMLNTLLQQQKLPPYEARLIGETGRNTLESLFYVGVYAGGKQLGKGAGSTQAQALDVAVRDALRRAF 280
Cdd:cd19873     6 SDLIKLENPK---RTLSALLKREGLEPPVSRLLKESGRASHTPTFVVGVYSGSQKLGEGAGSSIKMAEIRAARDALRKHY 82

                  .
gi 1173909449 281 G 281
Cdd:cd19873    83 L 83
DSRM_mL44_subfamily cd20315
double-stranded RNA binding motif of mL44 subfamily proteins; The mitochondrion-specific ...
210-280 1.40e-12

double-stranded RNA binding motif of mL44 subfamily proteins; The mitochondrion-specific ribosomal protein mL44 subfamily is composed of mitochondrial 54S ribosomal protein L3 (MRPL3) and mitochondrial 39S ribosomal protein L44 (MRPL44). MRPL3 (also known as mitochondrial large ribosomal subunit protein mL44) is a component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain. MRPL44 (also called L44mt, MRP-L44, or mitochondrial large ribosomal subunit protein mL44) is a component of the 39S subunit of mitochondrial ribosome. It may play a role in the assembly/stability of nascent mitochondrial polypeptides exiting the ribosome. Members of this family contain a RNase III-like domain and a double-stranded RNA binding motif (DSRM). DSRM is not sequence specific, but highly specific for dsRNAs of various origin and structure.


Pssm-ID: 380747  Cd Length: 71  Bit Score: 62.13  E-value: 1.40e-12
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1173909449 210 KDVTHMLNTLLQQQKLPPYEARLIGETGRNTLESLFYVGVYAGGKQLGKGAGSTQAQALDVAVRDALRRAF 280
Cdd:cd20315     1 ENPTRELAEILRREGIEKPVSRLIAESGRLTKSPVYIVGVYCDEETIGEGYGYSIKEAKAEAATDALMKLF 71
DSRM smart00358
Double-stranded RNA binding motif;
216-277 9.64e-04

Double-stranded RNA binding motif;


Pssm-ID: 214634 [Multi-domain]  Cd Length: 67  Bit Score: 37.24  E-value: 9.64e-04
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1173909449  216 LNTLLQQQKLPP-YEarLIGETGrNTLESLFYVGVYAGGKQLGKGAGSTQAQALDVAVRDALR 277
Cdd:smart00358   5 LQELAQKRKLPPeYE--LVKEEG-PDHAPRFTVTVKVGGKRTGEGEGSSKKEAKQRAAEAALR 64
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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