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Conserved domains on  [gi|74762241|sp|Q5T764|]
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RecName: Full=Interferon-induced protein with tetratricopeptide repeats 1B; AltName: Full=Interferon-induced protein with tetratricopeptide repeats 1-like protein

Protein Classification

tetratricopeptide repeat protein( domain architecture ID 18414217)

tetratricopeptide repeat (TPR) protein may adopt a right-handed helical structure with an amphipathic channel and may function as an interaction scaffold in the formation of multi-protein complexes; similar to Homo sapiens Interferon-induced protein with tetratricopeptide repeats 1

CATH:  1.25.40.10
Gene Ontology:  GO:0005515
PubMed:  30708253|10517866
SCOP:  3001345

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 156-425 1.32e-15

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


:

Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 76.69  E-value: 1.32e-15
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74762241 156 NYERAKTCFEKALEGNPENPEFNTGYAITVYRLDKFNTAsgrnkafsLHVLKRAVRLNPDDVYIRVLLALKLQDEGQEAE 235
Cdd:COG2956  23 QPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRA--------IRIHQKLLERDPDRAEALLELAQDYLKAGLLDR 94

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74762241 236 GEKYIEEALTSISSQAYVFQYAAKFYRRKGSVDKALELLKMALETTPTSAFLHHQMGLCYRAQmiqikeatnwqprGQdr 315
Cdd:COG2956  95 AEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQ-------------GD-- 159

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74762241 316 etvdrlVQLAICKFEKTIMLKRTFEMAYVDLAETYAEIGHHRKAEEHFQKGLRmkifEDQLKQEIHYHYGRFQEHHGKsQ 395
Cdd:COG2956 160 ------YDEAIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALE----QDPDYLPALPRLAELYEKLGD-P 228

                       250       260       270
                ....*....|....*....|....*....|
gi 74762241 396 DKAITHYLKGLKIEKMSHSREKLLNALEKL 425
Cdd:COG2956 229 EEALELLRKALELDPSDDLLLALADLLERK 258
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
51-244 6.79e-12

Tetratricopeptide (TPR) repeat [General function prediction only];


:

Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 65.41  E-value: 6.79e-12
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74762241  51 NVGIHNLLAYVKHLKGQNEEALVSLKKAEDLiqkehanqaDIRSLVTWGNFAWVYYHMGRLAEAQTYLDKVENTCKKFAN 130
Cdd:COG0457   7 DAEAYNNLGLAYRRLGRYEEAIEDYEKALEL---------DPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAE 77

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74762241 131 pSRYRMecpevdceeGWALAKCGgkNYERAKTCFEKALEGNPENPEFNTGYAITVYRLDKFNTAsgrnkafsLHVLKRAV 210
Cdd:COG0457  78 -ALNNL---------GLALQALG--RYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEA--------IEAYERAL 137

                       170       180       190
                ....*....|....*....|....*....|....
gi 74762241 211 RLNPDDVYIRVLLALKLQDEGQEAEGEKYIEEAL 244
Cdd:COG0457 138 ELDPDDADALYNLGIALEKLGRYEEALELLEKLE 171
 
Name Accession Description Interval E-value
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 156-425 1.32e-15

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 76.69  E-value: 1.32e-15
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74762241 156 NYERAKTCFEKALEGNPENPEFNTGYAITVYRLDKFNTAsgrnkafsLHVLKRAVRLNPDDVYIRVLLALKLQDEGQEAE 235
Cdd:COG2956  23 QPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRA--------IRIHQKLLERDPDRAEALLELAQDYLKAGLLDR 94

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74762241 236 GEKYIEEALTSISSQAYVFQYAAKFYRRKGSVDKALELLKMALETTPTSAFLHHQMGLCYRAQmiqikeatnwqprGQdr 315
Cdd:COG2956  95 AEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQ-------------GD-- 159

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74762241 316 etvdrlVQLAICKFEKTIMLKRTFEMAYVDLAETYAEIGHHRKAEEHFQKGLRmkifEDQLKQEIHYHYGRFQEHHGKsQ 395
Cdd:COG2956 160 ------YDEAIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALE----QDPDYLPALPRLAELYEKLGD-P 228

                       250       260       270
                ....*....|....*....|....*....|
gi 74762241 396 DKAITHYLKGLKIEKMSHSREKLLNALEKL 425
Cdd:COG2956 229 EEALELLRKALELDPSDDLLLALADLLERK 258
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
51-244 6.79e-12

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 65.41  E-value: 6.79e-12
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74762241  51 NVGIHNLLAYVKHLKGQNEEALVSLKKAEDLiqkehanqaDIRSLVTWGNFAWVYYHMGRLAEAQTYLDKVENTCKKFAN 130
Cdd:COG0457   7 DAEAYNNLGLAYRRLGRYEEAIEDYEKALEL---------DPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAE 77

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74762241 131 pSRYRMecpevdceeGWALAKCGgkNYERAKTCFEKALEGNPENPEFNTGYAITVYRLDKFNTAsgrnkafsLHVLKRAV 210
Cdd:COG0457  78 -ALNNL---------GLALQALG--RYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEA--------IEAYERAL 137

                       170       180       190
                ....*....|....*....|....*....|....
gi 74762241 211 RLNPDDVYIRVLLALKLQDEGQEAEGEKYIEEAL 244
Cdd:COG0457 138 ELDPDDADALYNLGIALEKLGRYEEALELLEKLE 171
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 36-298 6.79e-12

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 67.80  E-value: 6.79e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74762241    36 ENRIWEEIQFLD---TKY--NVGIHNLLAYVKHLKGQNEEALVSLKKAEDL---IQKEHANQADIRslvtwgnfawvyYH 107
Cdd:TIGR02917 172 ENRFDEARALIDevlTADpgNVDALLLKGDLLLSLGNIELALAAYRKAIALrpnNIAVLLALATIL------------IE 239

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74762241   108 MGRLAEAQTYLDKVEntcKKFAN-PSRYRMEcpevdceegwALAKCGGKNYERAKTCFEKALEGNPENPEFNTGYAITVY 186
Cdd:TIGR02917 240 AGEFEEAEKHADALL---KKAPNsPLAHYLK----------ALVDFQKKNYEDARETLQDALKSAPEYLPALLLAGASEY 306

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74762241   187 RLDKFNTAsgrnkafsLHVLKRAVRLNPDDVYIRVLLALKLQDEGQEAEGEKYIEEALTSISSQAYVFQYAAKFYRRKGS 266
Cdd:TIGR02917 307 QLGNLEQA--------YQYLNQILKYAPNSHQARRLLASIQLRLGRVDEAIATLSPALGLDPDDPAALSLLGEAYLALGD 378

                         250       260       270
                  ....*....|....*....|....*....|..
gi 74762241   267 VDKALELLKMALETTPTSAFLHHQMGLCYRAQ 298
Cdd:TIGR02917 379 FEKAAEYLAKATELDPENAAARTQLGISKLSQ 410
TPR_12 pfam13424
Tetratricopeptide repeat;
54-127 4.05e-04

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 38.91  E-value: 4.05e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 74762241    54 IHNLLAYVKHLKGQNEEALVSLKKAEDLIQKEHANQADIRsLVTWGNFAWVYYHMGRLAEAQTYLDKVENTCKK 127
Cdd:pfam13424   5 ALNNLAAVLRRLGRYDEALELLEKALEIARRLLGPDHPLT-ATTLLNLGRLYLELGRYEEALELLERALALAEK 77
 
Name Accession Description Interval E-value
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 156-425 1.32e-15

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 76.69  E-value: 1.32e-15
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74762241 156 NYERAKTCFEKALEGNPENPEFNTGYAITVYRLDKFNTAsgrnkafsLHVLKRAVRLNPDDVYIRVLLALKLQDEGQEAE 235
Cdd:COG2956  23 QPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRA--------IRIHQKLLERDPDRAEALLELAQDYLKAGLLDR 94

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74762241 236 GEKYIEEALTSISSQAYVFQYAAKFYRRKGSVDKALELLKMALETTPTSAFLHHQMGLCYRAQmiqikeatnwqprGQdr 315
Cdd:COG2956  95 AEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQ-------------GD-- 159

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74762241 316 etvdrlVQLAICKFEKTIMLKRTFEMAYVDLAETYAEIGHHRKAEEHFQKGLRmkifEDQLKQEIHYHYGRFQEHHGKsQ 395
Cdd:COG2956 160 ------YDEAIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALE----QDPDYLPALPRLAELYEKLGD-P 228

                       250       260       270
                ....*....|....*....|....*....|
gi 74762241 396 DKAITHYLKGLKIEKMSHSREKLLNALEKL 425
Cdd:COG2956 229 EEALELLRKALELDPSDDLLLALADLLERK 258
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 143-291 8.05e-14

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 73.87  E-value: 8.05e-14
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74762241 143 CEEGWALAKCGgkNYERAKTCFEKALEGNPENPEFNTGYAITVYRLDKFNTAsgrnkafsLHVLKRAVRLNPDDVYIRVL 222
Cdd:COG3914  82 ELAALLLQALG--RYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEA--------LAALRRALALNPDFAEAYLN 151

                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 74762241 223 LALKLQDEGQEAEGEKYIEEALTSISSQAYVFQYAAKFYRRKGSVDKALELLKMALETTPTSAFLHHQM 291
Cdd:COG3914 152 LGEALRRLGRLEEAIAALRRALELDPDNAEALNNLGNALQDLGRLEEAIAAYRRALELDPDNADAHSNL 220
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
146-298 9.86e-14

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 70.81  E-value: 9.86e-14
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74762241 146 GWALAKCGgkNYERAKTCFEKALEGNPENPEFNTGYAITVYRLDKFNTAsgrnkafsLHVLKRAVRLNPDDVYIRVLLAL 225
Cdd:COG0457  15 GLAYRRLG--RYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEA--------LADYEQALELDPDDAEALNNLGL 84

                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 74762241 226 KLQDEGQEAEGEKYIEEALTSISSQAYVFQYAAKFYRRKGSVDKALELLKMALETTPTSAFLHHQMGLCYRAQ 298
Cdd:COG0457  85 ALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKL 157
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
210-470 2.13e-12

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 66.95  E-value: 2.13e-12
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74762241 210 VRLNPDDVYIRVLLALKLQDEGQEAEGEKYIEEALTSISSQAYVFQYAAKFYRRKGSVDKALELLKMALETTPTSAFLHH 289
Cdd:COG0457   1 LELDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALN 80

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74762241 290 QMGLCYRAQmiqikeatnwqprGQDREtvdrlvqlAICKFEKTIMLKRTFEMAYVDLAETYAEIGHHRKAEEHFQKGLRM 369
Cdd:COG0457  81 NLGLALQAL-------------GRYEE--------ALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALEL 139

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74762241 370 kifeDQLKQEIHYHYGRFQEHHGKsQDKAITHYLKGLKIEKMSHSREKLLNALEKLAKRCIHQNVRVVESVSLLGLIHKL 449
Cdd:COG0457 140 ----DPDDADALYNLGIALEKLGR-YEEALELLEKLEAAALAALLAAALGEAALALAAAEVLLALLLALEQALRKKLAIL 214

                       250       260
                ....*....|....*....|.
gi 74762241 450 KGEVSDALLCYERALRLAADL 470
Cdd:COG0457 215 TLAALAELLLLALALLLALRL 235
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 155-298 5.04e-12

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 66.29  E-value: 5.04e-12
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74762241 155 KNYERAKTCFEKALEGNPENPEFNTGYAITVYRLDKFNTAsgrnkafsLHVLKRAVRLNPDDVYIRVLLALKLQDEGQEA 234
Cdd:COG2956  90 GLLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKA--------IEVLERLLKLGPENAHAYCELAELYLEQGDYD 161

                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 74762241 235 EGEKYIEEALTSISSQAYVFQYAAKFYRRKGSVDKALELLKMALETTPTSAFLHHQMGLCYRAQ 298
Cdd:COG2956 162 EAIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKL 225
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 155-282 5.59e-12

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 63.29  E-value: 5.59e-12
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74762241 155 KNYERAKTCFEKALEGNPENPEFNTGYAITVYRLDKFNTAsgrnkafsLHVLKRAVRLNPDDVYIRVLLALKLQDEGQEA 234
Cdd:COG4783  18 GDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEA--------IVLLHEALELDPDEPEARLNLGLALLKAGDYD 89

                        90       100       110       120
                ....*....|....*....|....*....|....*....|....*...
gi 74762241 235 EGEKYIEEALTSISSQAYVFQYAAKFYRRKGSVDKALELLKMALETTP 282
Cdd:COG4783  90 EALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALELDP 137
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
51-244 6.79e-12

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 65.41  E-value: 6.79e-12
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74762241  51 NVGIHNLLAYVKHLKGQNEEALVSLKKAEDLiqkehanqaDIRSLVTWGNFAWVYYHMGRLAEAQTYLDKVENTCKKFAN 130
Cdd:COG0457   7 DAEAYNNLGLAYRRLGRYEEAIEDYEKALEL---------DPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAE 77

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74762241 131 pSRYRMecpevdceeGWALAKCGgkNYERAKTCFEKALEGNPENPEFNTGYAITVYRLDKFNTAsgrnkafsLHVLKRAV 210
Cdd:COG0457  78 -ALNNL---------GLALQALG--RYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEA--------IEAYERAL 137

                       170       180       190
                ....*....|....*....|....*....|....
gi 74762241 211 RLNPDDVYIRVLLALKLQDEGQEAEGEKYIEEAL 244
Cdd:COG0457 138 ELDPDDADALYNLGIALEKLGRYEEALELLEKLE 171
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 36-298 6.79e-12

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 67.80  E-value: 6.79e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74762241    36 ENRIWEEIQFLD---TKY--NVGIHNLLAYVKHLKGQNEEALVSLKKAEDL---IQKEHANQADIRslvtwgnfawvyYH 107
Cdd:TIGR02917 172 ENRFDEARALIDevlTADpgNVDALLLKGDLLLSLGNIELALAAYRKAIALrpnNIAVLLALATIL------------IE 239

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74762241   108 MGRLAEAQTYLDKVEntcKKFAN-PSRYRMEcpevdceegwALAKCGGKNYERAKTCFEKALEGNPENPEFNTGYAITVY 186
Cdd:TIGR02917 240 AGEFEEAEKHADALL---KKAPNsPLAHYLK----------ALVDFQKKNYEDARETLQDALKSAPEYLPALLLAGASEY 306

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74762241   187 RLDKFNTAsgrnkafsLHVLKRAVRLNPDDVYIRVLLALKLQDEGQEAEGEKYIEEALTSISSQAYVFQYAAKFYRRKGS 266
Cdd:TIGR02917 307 QLGNLEQA--------YQYLNQILKYAPNSHQARRLLASIQLRLGRVDEAIATLSPALGLDPDDPAALSLLGEAYLALGD 378

                         250       260       270
                  ....*....|....*....|....*....|..
gi 74762241   267 VDKALELLKMALETTPTSAFLHHQMGLCYRAQ 298
Cdd:TIGR02917 379 FEKAAEYLAKATELDPENAAARTQLGISKLSQ 410
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 222-474 2.59e-11

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 63.98  E-value: 2.59e-11
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74762241 222 LLALKLQDEGQEAEGEKYIEEALTSISSQAYVFQYAAKFYRRKGSVDKALELLKMALETTPTSAFLHHQMGLCYRAQmiq 301
Cdd:COG2956  13 FKGLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKA--- 89

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74762241 302 ikeatnwqprgqdretvdRLVQLAICKFEKTIMLKRTFEMAYVDLAETYAEIGHHRKAEEHFQKGLRMKifedqlKQEIH 381
Cdd:COG2956  90 ------------------GLLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLG------PENAH 145

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74762241 382 YHYGRFQEHHGKSQ-DKAITHYLKGLKIEKMS----------HSREKLLNALEKLAKRCIHQNVRVVESVSLLGLIHKLK 450
Cdd:COG2956 146 AYCELAELYLEQGDyDEAIEALEKALKLDPDCarallllaelYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKL 225

                       250       260
                ....*....|....*....|....
gi 74762241 451 GEVSDALLCYERALRLAADLNPIF 474
Cdd:COG2956 226 GDPEEALELLRKALELDPSDDLLL 249
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
168-432 2.68e-11

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 63.49  E-value: 2.68e-11
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74762241 168 LEGNPENPEFNTGYAITVYRLDKFNTAsgrnkafsLHVLKRAVRLNPDDVYIRVLLALKLQDEGQEAEGEKYIEEALTSI 247
Cdd:COG0457   1 LELDPDDAEAYNNLGLAYRRLGRYEEA--------IEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELD 72

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74762241 248 SSQAYVFQYAAKFYRRKGSVDKALELLKMALETTPTSAFLHHQMGLCYRAQmiqikeatnwqprGQDREtvdrlvqlAIC 327
Cdd:COG0457  73 PDDAEALNNLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLEL-------------GRYDE--------AIE 131

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74762241 328 KFEKTIMLKRTFEMAYVDLAETYAEIGHHRKAEEHFQKGLRMKIFEDQLKQEIHYHYGRFQEHHGKSQDKAITHYLKGLK 407
Cdd:COG0457 132 AYERALELDPDDADALYNLGIALEKLGRYEEALELLEKLEAAALAALLAAALGEAALALAAAEVLLALLLALEQALRKKL 211

                       250       260
                ....*....|....*....|....*
gi 74762241 408 IEKMSHSREKLLNALEKLAKRCIHQ 432
Cdd:COG0457 212 AILTLAALAELLLLALALLLALRLA 236
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 50-321 3.18e-11

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 65.40  E-value: 3.18e-11
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74762241  50 YNVGIHNLLAYVKHLKGQNEEALVSLKKAEDLIQKEHANQADIRSLvtwgnFAWVYYHMGRLAEAQTYLDKVENtckkfA 129
Cdd:COG3914  38 AAALGLALLLLAALAEAAAAALLALAAGEAAAAAAALLLLAALLEL-----AALLLQALGRYEEALALYRRALA-----L 107

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74762241 130 NPSryrmeCPEVDCEEGWALAKCGgkNYERAKTCFEKALEGNPENPEFNTGYAITVYRLDKFNTAsgrnkafsLHVLKRA 209
Cdd:COG3914 108 NPD-----NAEALFNLGNLLLALG--RLEEALAALRRALALNPDFAEAYLNLGEALRRLGRLEEA--------IAALRRA 172

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74762241 210 VRLNPDDVYIRVLLALKLQDEGQEAEGEKYIEEALTSISSQAYVFQYAAKFYRRKGSVDKALELLK-----MALETTPTS 284
Cdd:COG3914 173 LELDPDNAEALNNLGNALQDLGRLEEAIAAYRRALELDPDNADAHSNLLFALRQACDWEVYDRFEEllaalARGPSELSP 252

                       250       260       270       280
                ....*....|....*....|....*....|....*....|....*.
gi 74762241 285 AFLHHQMGL-------CYR--AQMIQIKEATNWQPRGQDRETVDRL 321
Cdd:COG3914 253 FALLYLPDDdpaellaLARawAQLVAAAAAPELPPPPNPRDPDRKL 298
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
89-279 7.63e-11

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 62.33  E-value: 7.63e-11
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74762241  89 QADIRSLVTWGNFAWVYYHMGRLAEAQTYLDKVENTCKKFANPSRYRmecpevdceeGWALAKCGgkNYERAKTCFEKAL 168
Cdd:COG0457   2 ELDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNL----------GLAYLRLG--RYEEALADYEQAL 69

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74762241 169 EGNPENPEFNTGYAITVYRLDKFNTAsgrnkafsLHVLKRAVRLNPDDVYIRVLLALKLQDEGQEAEGEKYIEEALTSIS 248
Cdd:COG0457  70 ELDPDDAEALNNLGLALQALGRYEEA--------LEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDP 141

                       170       180       190
                ....*....|....*....|....*....|.
gi 74762241 249 SQAYVFQYAAKFYRRKGSVDKALELLKMALE 279
Cdd:COG0457 142 DDADALYNLGIALEKLGRYEEALELLEKLEA 172
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 155-368 1.22e-10

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 62.05  E-value: 1.22e-10
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74762241 155 KNYERAKTCFEKALEGNPENPEFNTGYAITVYRLDKFNTAsgrnkafsLHVLKRAVRLNPDDVYIRVLLALKLQDEGQEA 234
Cdd:COG2956  56 GEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGLLDRA--------EELLEKLLELDPDDAEALRLLAEIYEQEGDWE 127

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74762241 235 EGEKYIEEALTSISSQAYVFQYAAKFYRRKGSVDKALELLKMALETTPTSAFLHHQMGLCYRAQmiqikeatnwqprGQD 314
Cdd:COG2956 128 KAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKALKLDPDCARALLLLAELYLEQ-------------GDY 194

                       170       180       190       200       210
                ....*....|....*....|....*....|....*....|....*....|....
gi 74762241 315 REtvdrlvqlAICKFEKTIMLKRTFEMAYVDLAETYAEIGHHRKAEEHFQKGLR 368
Cdd:COG2956 195 EE--------AIAALERALEQDPDYLPALPRLAELYEKLGDPEEALELLRKALE 240
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 156-244 2.49e-09

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 55.40  E-value: 2.49e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74762241 156 NYERAKTCFEKALEGNPENPEFNTGYAITVYRLDKFNTAsgrnkafsLHVLKRAVRLNPDDVYIRVLLALKLQDEGQEAE 235
Cdd:COG4235  32 RYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEA--------EELLERALALDPDNPEALYLLGLAAFQQGDYAE 103


                ....*....
gi 74762241 236 GEKYIEEAL 244
Cdd:COG4235 104 AIAAWQKLL 112
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 159-285 3.32e-09

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 55.01  E-value: 3.32e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74762241 159 RAKTCFEKALEGNPENPEFNTGYAITVYRLDKFNTAsgrnkafsLHVLKRAVRLNPDDVYIRVLLALKLQDEGQEAEGEK 238
Cdd:COG4235   1 EAIARLRQALAANPNDAEGWLLLGRAYLRLGRYDEA--------LAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEE 72

                        90       100       110       120
                ....*....|....*....|....*....|....*....|....*..
gi 74762241 239 YIEEALTSISSQAYVFQYAAKFYRRKGSVDKALELLKMALETTPTSA 285
Cdd:COG4235  73 LLERALALDPDNPEALYLLGLAAFQQGDYAEAIAAWQKLLALLPADA 119
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 206-298 7.09e-09

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 54.43  E-value: 7.09e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74762241 206 LKRAVRLNPDDVYIRVLLALKLQDEGQEAEGEKYIEEALTSISSQAYVFQYAAKFYRRKGSVDKALELLKMALETTPTSA 285
Cdd:COG4783  27 LEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKAGDYDEALALLEKALKLDPEHP 106

                        90
                ....*....|...
gi 74762241 286 FLHHQMGLCYRAQ 298
Cdd:COG4783 107 EAYLRLARAYRAL 119
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 216-370 1.00e-08

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 53.66  E-value: 1.00e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74762241 216 DVYIRVLLALKLQDEGQEAEGEKYIEEALTSISSQAYVFQYAAKFYRRKGSVDKALELLKMALETTPTSAFLHHQMGLCY 295
Cdd:COG4783   3 CAEALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLAL 82

                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 74762241 296 RAQmiqikeatnwqprGQDREtvdrlvqlAICKFEKTIMLKRTFEMAYVDLAETYAEIGHHRKAEEHFQKGLRMK 370
Cdd:COG4783  83 LKA-------------GDYDE--------ALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALELD 136
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 51-279 1.32e-08

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 55.89  E-value: 1.32e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74762241  51 NVGIHNLLAYVKHLKGQNEEALVSLKKAEDLIQKEHANQADIrslvtwgnfAWVYYHMGRLAEAQTYLDKVENTcKKFAN 130
Cdd:COG2956  41 TVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLEL---------AQDYLKAGLLDRAEELLEKLLEL-DPDDA 110

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74762241 131 PSRYRM-------------------------ECPEVDCEegWALAKCGGKNYERAKTCFEKALEGNPENPEFNTGYAITV 185
Cdd:COG2956 111 EALRLLaeiyeqegdwekaievlerllklgpENAHAYCE--LAELYLEQGDYDEAIEALEKALKLDPDCARALLLLAELY 188

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74762241 186 YRLDKFNTAsgrnkafsLHVLKRAVRLNPDDVYIRVLLALKLQDEGQEAEGEKYIEEALtSISSQAYVFQYAAKFYRRKG 265
Cdd:COG2956 189 LEQGDYEEA--------IAALERALEQDPDYLPALPRLAELYEKLGDPEEALELLRKAL-ELDPSDDLLLALADLLERKE 259

                       250
                ....*....|....
gi 74762241 266 SVDKALELLKMALE 279
Cdd:COG2956 260 GLEAALALLERQLR 273
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 251-474 6.22e-08

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 53.96  E-value: 6.22e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74762241 251 AYVFQYAAKFYRRKGSVDKALELLKMALETTPTSAFLHHQMGLCYRAqmiqikeatnwqpRGQdretVDRLVQLaickFE 330
Cdd:COG2956   8 ALGWYFKGLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRR-------------RGE----YDRAIRI----HQ 66

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74762241 331 KTIMLKRTFEMAYVDLAETYAEIGHHRKAEEHFQKGLRmkifEDQLKQEIHYHYGRFQEHHGKSqDKAITHYLKGLKIEK 410
Cdd:COG2956  67 KLLERDPDRAEALLELAQDYLKAGLLDRAEELLEKLLE----LDPDDAEALRLLAEIYEQEGDW-EKAIEVLERLLKLGP 141

                       170       180       190       200       210       220       230
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 74762241 411 ----------MSHSREKLLNALEKLAKRCIHQNVRVVESVSLLGLIHKLKGEVSDALLCYERALRLAADLNPIF 474
Cdd:COG2956 142 enahaycelaELYLEQGDYDEAIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPAL 215
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
155-244 6.90e-08

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 50.17  E-value: 6.90e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74762241 155 KNYERAKTCFEKALEGNPENPEFNTGYAITVYRLDKFNTAsgrnkafslHVLKRAVRLNPDDVYIRVLLALKLQDEGQEA 234
Cdd:COG3063   6 GDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEA---------IALEKALKLDPNNAEALLNLAELLLELGDYD 76

                        90
                ....*....|
gi 74762241 235 EGEKYIEEAL 244
Cdd:COG3063  77 EALAYLERAL 86
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
55-258 1.61e-07

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 52.32  E-value: 1.61e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74762241  55 HNLLAYVKHLKGQNEEALVSLKKAEDLiqkehanqaDIRSLVTWGNFAWVYYHMGRLAEAQTYLDKVENTCKKFANPSRY 134
Cdd:COG0457  45 LYNLGLAYLRLGRYEEALADYEQALEL---------DPDDAEALNNLGLALQALGRYEEALEDYDKALELDPDDAEALYN 115

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74762241 135 RmecpevdceeGWALAKCGgkNYERAKTCFEKALEGNPENPEFNTGYAITVYRLDKFNTASGR-NKAFSLHVLKRAVRLN 213
Cdd:COG0457 116 L----------GLALLELG--RYDEAIEAYERALELDPDDADALYNLGIALEKLGRYEEALELlEKLEAAALAALLAAAL 183

                       170       180       190       200
                ....*....|....*....|....*....|....*....|....*
gi 74762241 214 PDDVYIRVLLALKLQDEGQEAEGEKYIEEALTSISSQAYVFQYAA 258
Cdd:COG0457 184 GEAALALAAAEVLLALLLALEQALRKKLAILTLAALAELLLLALA 228
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
250-472 3.26e-07

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 51.55  E-value: 3.26e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74762241 250 QAYVFQYAAKFYRRKGSVDKALELLKMALETTPTSAFLHHQMGLCYRAQmiqikeatnwqprGQDREtvdrlvqlAICKF 329
Cdd:COG0457   7 DAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRL-------------GRYEE--------ALADY 65

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74762241 330 EKTIMLKRTFEMAYVDLAETYAEIGHHRKAEEHFQKGLRMkifeDQLKQEIHYHYGRFQEHHGKSqDKAITHYLKGLKIe 409
Cdd:COG0457  66 EQALELDPDDAEALNNLGLALQALGRYEEALEDYDKALEL----DPDDAEALYNLGLALLELGRY-DEAIEAYERALEL- 139

                       170       180       190       200       210       220
                ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 74762241 410 kmshsrekllnaleklakrcihqNVRVVESVSLLGLIHKLKGEVSDALLCYERALRLAADLNP 472
Cdd:COG0457 140 -----------------------DPDDADALYNLGIALEKLGRYEEALELLEKLEAAALAALL 179
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 269-474 3.29e-07

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 52.69  E-value: 3.29e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74762241 269 KALELLKMALETTPTSAFLHHQMGLCYRAQMIQIKEATNWQPRGQDRETVDRLvQLAICKFEKTIMLKRTFEMAYVDLAE 348
Cdd:COG3914  42 GLALLLLAALAEAAAAALLALAAGEAAAAAAALLLLAALLELAALLLQALGRY-EEALALYRRALALNPDNAEALFNLGN 120

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74762241 349 TYAEIGHHRKAEEHFQKGLRMKifEDQLkqEIHYHYGRFQEHHGKsQDKAITHYLKGLKIEKmshsrekllNALEklakr 428
Cdd:COG3914 121 LLLALGRLEEALAALRRALALN--PDFA--EAYLNLGEALRRLGR-LEEAIAALRRALELDP---------DNAE----- 181

                       170       180       190       200
                ....*....|....*....|....*....|....*....|....*.
gi 74762241 429 cIHQNvrvvesvslLGLIHKLKGEVSDALLCYERALRLAADLNPIF 474
Cdd:COG3914 182 -ALNN---------LGNALQDLGRLEEAIAAYRRALELDPDNADAH 217
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 51-289 1.08e-06

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 51.24  E-value: 1.08e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74762241    51 NVGIHNLLAYVKHLKGQNEEALVSLKKAedlIQKEHANQADIRSLVTWgnfawvYYHMGRLAEAQTYLDKVENTCKKfaN 130
Cdd:TIGR02917 532 NLRAILALAGLYLRTGNEEEAVAWLEKA---AELNPQEIEPALALAQY------YLGKGQLKKALAILNEAADAAPD--S 600

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74762241   131 PSRYRMecpevdceegWALAKCGGKNYERAKTCFEKALEGNPENPEfntgyaiTVYRLDKFNtASGRNKAFSLHVLKRAV 210
Cdd:TIGR02917 601 PEAWLM----------LGRAQLAAGDLNKAVSSFKKLLALQPDSAL-------ALLLLADAY-AVMKNYAKAITSLKRAL 662

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74762241   211 RLNPDDVYIRVLLALKLQDEGQEAEGEKYIEEALTSISSQAYVFQYAAKFYRRKGSVDKALELLKMALETTPTS---AFL 287
Cdd:TIGR02917 663 ELKPDNTEAQIGLAQLLLAAKRTESAKKIAKSLQKQHPKAALGFELEGDLYLRQKDYPAAIQAYRKALKRAPSSqnaIKL 742


                  ..
gi 74762241   288 HH 289
Cdd:TIGR02917 743 HR 744
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 155-468 4.45e-06

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 49.31  E-value: 4.45e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74762241   155 KNYERAKTCFEKALEGNPENPEFNTGYAItvyrldkFNTASGR-NKAFSlhVLKRAVRLNPDDVYIRVLLALKLQDEGQE 233
Cdd:TIGR02917 377 GDFEKAAEYLAKATELDPENAAARTQLGI-------SKLSQGDpSEAIA--DLETAAQLDPELGRADLLLILSYLRSGQF 447

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74762241   234 AEGEKYIEEALTSISSQAYVFQYAAKFYRRKGSVDKALELLKMALETTPTSAF-------LHHQMGLCYRAQ-----MIQ 301
Cdd:TIGR02917 448 DKALAAAKKLEKKQPDNASLHNLLGAIYLGKGDLAKAREAFEKALSIEPDFFPaaanlarIDIQEGNPDDAIqrfekVLT 527

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74762241   302 I---------------------KEATNW--QPRGQDRETVDRLVQL------------AICKFEKTIMLKRTFEMAYVDL 346
Cdd:TIGR02917 528 IdpknlrailalaglylrtgneEEAVAWleKAAELNPQEIEPALALaqyylgkgqlkkALAILNEAADAAPDSPEAWLML 607

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74762241   347 AETYAEIGHHRKAEEHFQKGLRmkifEDQLKQEIHYHYGRFQEHHgKSQDKAITHYLKGLKIEKmSHSREKLL------- 419
Cdd:TIGR02917 608 GRAQLAAGDLNKAVSSFKKLLA----LQPDSALALLLLADAYAVM-KNYAKAITSLKRALELKP-DNTEAQIGlaqllla 681

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|...
gi 74762241   420 ----NALEKLAKRCIHQNVRVVESVSLLGLIHKLKGEVSDALLCYERALRLAA 468
Cdd:TIGR02917 682 akrtESAKKIAKSLQKQHPKAALGFELEGDLYLRQKDYPAAIQAYRKALKRAP 734
HemYx COG3071
Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to ...
 206-369 5.55e-06

Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to protoporphyrinogen oxidase HemY) [Function unknown];


Pssm-ID: 442305 [Multi-domain]  Cd Length: 323  Bit Score: 48.37  E-value: 5.55e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74762241 206 LKRAVRLNPDdvyIRVLLALKLQDEGQEAEGEKYIEEALTSISSQAYVFQYAAkfyRRKGSVDKALELLKMALETTPTSA 285
Cdd:COG3071 185 LPRAERRDPE---LAAAYARALIALGDHDEAERLLREALKRQWDPRLVRLYGR---LQGGDPAKQLKRAEKWLKKHPNDP 258

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74762241 286 FLHHQMG-LCYRAQmiqikeatNWqprGQDRETvdrlvqlaickFEKTIMLKRTFEmAYVDLAETYAEIGHHRKAEEHFQ 364
Cdd:COG3071 259 DLLLALGrLCLRNQ--------LW---GKAREY-----------LEAALALRPSAE-AYAELARLLEQLGDPEEAAEHYR 315


                ....*
gi 74762241 365 KGLRM 369
Cdd:COG3071 316 KALAL 320
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 51-174 6.90e-06

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 45.57  E-value: 6.90e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74762241  51 NVGIHNLLAYVKHLKGQNEEALVSLKKAEDLIQKEHAnqadirslvTWGNFAWVYYHMGRLAEAQTYLDKVENtckkfAN 130
Cdd:COG4783  37 NPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPE---------ARLNLGLALLKAGDYDEALALLEKALK-----LD 102

                        90       100       110       120
                ....*....|....*....|....*....|....*....|....
gi 74762241 131 PsryrmECPEVDCEEGWALAKCGgkNYERAKTCFEKALEGNPEN 174
Cdd:COG4783 103 P-----EHPEAYLRLARAYRALG--RPDEAIAALEKALELDPDD 139
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
206-282 1.25e-05

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 43.62  E-value: 1.25e-05
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 74762241 206 LKRAVRLNPDDVYIRVLLALKLQDEGQEAEGEKYiEEALTSISSQAYVFQYAAKFYRRKGSVDKALELLKMALETTP 282
Cdd:COG3063  15 YEKALELDPDNADALNNLGLLLLEQGRYDEAIAL-EKALKLDPNNAEALLNLAELLLELGDYDEALAYLERALELDP 90
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
261-370 1.30e-05

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 43.62  E-value: 1.30e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74762241 261 YRRKGSVDKALELLKMALETTPTSAFLHHQMGLCYRAQmiqikeatnwqprGQDREtvdrlvqlAIcKFEKTIMLKRTFE 340
Cdd:COG3063   2 YLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQ-------------GRYDE--------AI-ALEKALKLDPNNA 59

                        90       100       110
                ....*....|....*....|....*....|
gi 74762241 341 MAYVDLAETYAEIGHHRKAEEHFQKGLRMK 370
Cdd:COG3063  60 EALLNLAELLLELGDYDEALAYLERALELD 89
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 248-409 1.46e-05

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 44.80  E-value: 1.46e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74762241 248 SSQAYVFQYAAKFYRRKGSVDKALELLKMALETTPTSAFLHHQMGLCYRAQmiqikeatnwqprGQDREtvdrlvqlAIC 327
Cdd:COG4783   1 AACAEALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQL-------------GDLDE--------AIV 59

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74762241 328 KFEKTIMLKRTFEMAYVDLAETYAEIGHHRKAEEHFQKGLRMkifeDQLKQEIHYHYGRFQEHHGKsQDKAITHYLKGLK 407
Cdd:COG4783  60 LLHEALELDPDEPEARLNLGLALLKAGDYDEALALLEKALKL----DPEHPEAYLRLARAYRALGR-PDEAIAALEKALE 134


                ..
gi 74762241 408 IE 409
Cdd:COG4783 135 LD 136
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 54-285 1.81e-05

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 47.39  E-value: 1.81e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74762241    54 IHNLLAYVKHLKGQNEEALVSLKKAEDLiqKEHANQADIRslvtwgnfawvyyhMGRLAEAQTYLDKVENTCKKFANPsr 133
Cdd:TIGR02917 637 ALLLLADAYAVMKNYAKAITSLKRALEL--KPDNTEAQIG--------------LAQLLLAAKRTESAKKIAKSLQKQ-- 698

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74762241   134 yRMECPEVDCEEGW-ALAKcggKNYERAKTCFEKALEGNPEnpefntgyAITVYRLDKFNTASGRNKAfSLHVLKRAVRL 212
Cdd:TIGR02917 699 -HPKAALGFELEGDlYLRQ---KDYPAAIQAYRKALKRAPS--------SQNAIKLHRALLASGNTAE-AVKTLEAWLKT 765

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 74762241   213 NPDDVYIRVLLALKLQDEGQEAEGEKYIEEALTSISSQAYVFQYAAKFYrRKGSVDKALELLKMALETTPTSA 285
Cdd:TIGR02917 766 HPNDAVLRTALAELYLAQKDYDKAIKHYQTVVKKAPDNAVVLNNLAWLY-LELKDPRALEYAERALKLAPNIP 837
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 155-473 1.96e-05

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 47.39  E-value: 1.96e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74762241   155 KNYERAKTCFEKALEGNPENPEFNTGYAitvyrldKFNTASGRNKAfSLHVLKRAVRLNPDDVYIRVLLALKLQDEGQEA 234
Cdd:TIGR02917 513 GNPDDAIQRFEKVLTIDPKNLRAILALA-------GLYLRTGNEEE-AVAWLEKAAELNPQEIEPALALAQYYLGKGQLK 584

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74762241   235 EGEKYIEEALTSISSQAYVFQYAAKFYRRKGSVDKALELLKMALETTPTSAFLHHQMGLCYRAQ------MIQIKEATNW 308
Cdd:TIGR02917 585 KALAILNEAADAAPDSPEAWLMLGRAQLAAGDLNKAVSSFKKLLALQPDSALALLLLADAYAVMknyakaITSLKRALEL 664

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74762241   309 QPrgQDRETVDRLVQLAIC--KFEKTIMLKRTFEMAYVD-------LAETYAEIGHHRKAEEHFQKGLR----------- 368
Cdd:TIGR02917 665 KP--DNTEAQIGLAQLLLAakRTESAKKIAKSLQKQHPKaalgfelEGDLYLRQKDYPAAIQAYRKALKrapssqnaikl 742

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74762241   369 -------------MKIFEDQLKQEIHYHYGRFQEH----HGKSQDKAITHYLKGLKIEkmshsrEKLLNALEKLAKrcih 431
Cdd:TIGR02917 743 hrallasgntaeaVKTLEAWLKTHPNDAVLRTALAelylAQKDYDKAIKHYQTVVKKA------PDNAVVLNNLAW---- 812

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|..
gi 74762241   432 qnvrvvesvsllgLIHKLKGevSDALLCYERALRLAADLNPI 473
Cdd:TIGR02917 813 -------------LYLELKD--PRALEYAERALKLAPNIPAI 839
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 202-282 1.97e-05

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 44.57  E-value: 1.97e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74762241 202 SLHVLKRAVRLNPDDVYIRVLLALKLQDEGQEAEGEKYIEEALTSISSQAYVFQYAAKFYRRKGSVDKALELLKMALETT 281
Cdd:COG5010  73 SLALLEQALQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAALQRALGTS 152


                .
gi 74762241 282 P 282
Cdd:COG5010 153 P 153
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 206-298 3.75e-05

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 43.46  E-value: 3.75e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74762241 206 LKRAVRLNPDDVYIRVLLALKLQDEGQEAEGEKYIEEALTSISSQAYVFQYAAKFYRRKGSVDKALELLKMALETTPTSA 285
Cdd:COG4235   6 LRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALALDPDNP 85

                        90
                ....*....|...
gi 74762241 286 FLHHQMGLCYRAQ 298
Cdd:COG4235  86 EALYLLGLAAFQQ 98
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 69-214 2.58e-04

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 41.48  E-value: 2.58e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74762241  69 EEALVSLKKAEDLIQKEHANQADIRSLVTWGNFAWVYYHMGRLAEAQTYLDKVENTCKKFANPSRYRmecpevdceeGWA 148
Cdd:COG5010  28 EAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPNNPELYYNL----------ALL 97

                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 74762241 149 LAKCGgkNYERAKTCFEKALEGNPENPEFNTGYAITVYRLDKFNTAsgrnkafsLHVLKRAVRLNP 214
Cdd:COG5010  98 YSRSG--DKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEA--------KAALQRALGTSP 153
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 200-368 3.09e-04

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 41.10  E-value: 3.09e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74762241 200 AFSLHVLKRAVRLNPDDVYIRVLLALKLQDEGQEAEGEKYIEEALTSISSQAYVFQYAAKFYRRKGSVDKALELLKMALE 279
Cdd:COG5010   3 ALEGFDRLPLYLLLLTKLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQ 82

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74762241 280 TTPTSAFLHHQMGLCYRAQmiqikeatnwqprGQDREtvdrlvqlAICKFEKTIMLKRTFEMAYVDLAETYAEIGHHRKA 359
Cdd:COG5010  83 LDPNNPELYYNLALLYSRS-------------GDKDE--------AKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEA 141


                ....*....
gi 74762241 360 EEHFQKGLR 368
Cdd:COG5010 142 KAALQRALG 150
TPR_12 pfam13424
Tetratricopeptide repeat;
54-127 4.05e-04

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 38.91  E-value: 4.05e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 74762241    54 IHNLLAYVKHLKGQNEEALVSLKKAEDLIQKEHANQADIRsLVTWGNFAWVYYHMGRLAEAQTYLDKVENTCKK 127
Cdd:pfam13424   5 ALNNLAAVLRRLGRYDEALELLEKALEIARRLLGPDHPLT-ATTLLNLGRLYLELGRYEEALELLERALALAEK 77
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 148-469 5.13e-04

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 42.76  E-value: 5.13e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74762241   148 ALAKCGGKN----YERAKTCFEK------------ALEGNPENPEFNtgyaitvYRLDKFNTASGrNKAFSLHVLKRAVR 211
Cdd:TIGR02917  13 ALSACGDQSpeelIEAAKSYLQKnkykaaiiqlknALQKDPNDAEAR-------FLLGKIYLALG-DYAAAEKELRKALS 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74762241   212 LNPDDVYIRVLLA--LKLQDEGQEAEGEKyieEALTSISS--QAYVFQYAAKFYRRKGSVDKALELLKMALETTPTsaFL 287
Cdd:TIGR02917  85 LGYPKNQVLPLLAraYLLQGKFQQVLDEL---PGKTLLDDegAAELLALRGLAYLGLGQLELAQKSYEQALAIDPR--SL 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74762241   288 HHQMGLCY-RAQMIQIKEATNWQPR--GQDRETVDRLV------------QLAICKFEKTIMLKRTFEMAYVDLAETYAE 352
Cdd:TIGR02917 160 YAKLGLAQlALAENRFDEARALIDEvlTADPGNVDALLlkgdlllslgniELALAAYRKAIALRPNNIAVLLALATILIE 239

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74762241   353 IGHHRKAEEHFQ---KGLRMKIFEDQLKQEIHYHYGRFQEHHGKSQD--KAITHYLKGLKIEKMSH-SREKLLNA---LE 423
Cdd:TIGR02917 240 AGEFEEAEKHADallKKAPNSPLAHYLKALVDFQKKNYEDARETLQDalKSAPEYLPALLLAGASEyQLGNLEQAyqyLN 319

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....*.
gi 74762241   424 KLAKRCIHQnvrvVESVSLLGLIHKLKGEVSDALLCYERALRLAAD 469
Cdd:TIGR02917 320 QILKYAPNS----HQARRLLASIQLRLGRVDEAIATLSPALGLDPD 361
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 269-425 5.97e-04

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 39.99  E-value: 5.97e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74762241 269 KALELLKMALETTPTSAFLHHQMGLCYRAQMiQIKEATNWqprgqdretvdrlvqlaickFEKTIMLKRTFEMAYVDLAE 348
Cdd:COG4235   1 EAIARLRQALAANPNDAEGWLLLGRAYLRLG-RYDEALAA--------------------YEKALRLDPDNADALLDLAE 59

                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 74762241 349 TYAEIGHHRKAEEHFQKGLRMkifeDQLKQEIHYHYGRFQEHHGKSqDKAITHYLKGLKIEKMSHSREKLLNALEKL 425
Cdd:COG4235  60 ALLAAGDTEEAEELLERALAL----DPDNPEALYLLGLAAFQQGDY-AEAIAAWQKLLALLPADAPARLLEASIAEA 131
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
51-242 1.34e-03

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 40.38  E-value: 1.34e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74762241  51 NVGIHNLLAYVKHLKGQNEEALVSLKKAEDLiqkehanqaDIRSLVTWGNFAWVYYHMGRLAEAQTYLDKVENTCKKFAN 130
Cdd:COG0457  75 DAEALNNLGLALQALGRYEEALEDYDKALEL---------DPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDAD 145

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74762241 131 PSRYRmecpevdceeGWALAKCGgkNYERAKTCFEKALEGNPENPEFNTGYAITVYRLDKFNTASGRNKAFSLHVLKRAV 210
Cdd:COG0457 146 ALYNL----------GIALEKLG--RYEEALELLEKLEAAALAALLAAALGEAALALAAAEVLLALLLALEQALRKKLAI 213

                       170       180       190
                ....*....|....*....|....*....|..
gi 74762241 211 RLNPDDVYIRVLLALKLQDEGQEAEGEKYIEE 242
Cdd:COG0457 214 LTLAALAELLLLALALLLALRLAALALYQYRA 245
3a0801s09 TIGR00990
mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) ...
 154-306 1.79e-03

mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70); [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273380 [Multi-domain]  Cd Length: 615  Bit Score: 40.74  E-value: 1.79e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74762241   154 GKNYERAKTCFEKALEGNPENPEFNTGYAITvyrlDKFNTASGRNKAfSLHVLKRAVRLNPDDVYIRVLLALKLQDEGQE 233
Cdd:TIGR00990 307 DESYEEAARAFEKALDLGKLGEKEAIALNLR----GTFKCLKGKHLE-ALADLSKSIELDPRVTQSYIKRASMNLELGDP 381

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 74762241   234 AEGEKYIEEALTSISSQAYVFQYAAKFYRRKGSVDKALELLKMALETTPTSAFLHHQMG-LCYRAQMIQIKEAT 306
Cdd:TIGR00990 382 DKAEEDFDKALKLNSEDPDIYYHRAQLHFIKGEFAQAGKDYQKSIDLDPDFIFSHIQLGvTQYKEGSIASSMAT 455
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
155-277 2.87e-03

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 39.13  E-value: 2.87e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74762241 155 KNYERAKTCFEKALEGNPENPE--FNTGYAitvyrldkfNTASGRNKAfSLHVLKRAVRLNPDDVYIRVLLALKLQDEGQ 232
Cdd:COG4785  87 GDYDLAIADFDQALELDPDLAEayNNRGLA---------YLLLGDYDA-ALEDFDRALELDPDYAYAYLNRGIALYYLGR 156

                        90       100       110       120
                ....*....|....*....|....*....|....*....|....*..
gi 74762241 233 EAEGEKYIEEA--LTSISSQAYVFQYaakFYRRKGSVDKALELLKMA 277
Cdd:COG4785 157 YELAIADLEKAleLDPNDPERALWLY---LAERKLDPEKALALLLED 200
COG4700 COG4700
Uncharacterized conserved protein ECs_4300, contains TPR-like domain [Function unknown];
155-280 9.35e-03

Uncharacterized conserved protein ECs_4300, contains TPR-like domain [Function unknown];


Pssm-ID: 443735 [Multi-domain]  Cd Length: 249  Bit Score: 37.94  E-value: 9.35e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74762241 155 KNYERAKTCFEKALEGN-PENPEFNTGYAITVYRLDKFNTAsgrnkafsLHVLKRAVRLNPD----DVYIrvLLALKLQD 229
Cdd:COG4700 103 GRYDEAIELYEEALTGIfADDPHILLGLAQALFELGRYAEA--------LETLEKLIAKNPDfkssDAHL--LYARALEA 172

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|.
gi 74762241 230 EGQEAEGEKYIEEALTSISSQAYVFQYAaKFYRRKGSVDKALELLKMALET 280
Cdd:COG4700 173 LGDLEAAEAELEALARRYSGPEARYRYA-KFLARQGRTAEAKELLEEILDE 222
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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