|
Name |
Accession |
Description |
Interval |
E-value |
| TyrB |
COG1448 |
Aspartate/aromatic aminotransferase [Amino acid transport and metabolism]; Aspartate/aromatic ... |
1-393 |
0e+00 |
|
Aspartate/aromatic aminotransferase [Amino acid transport and metabolism]; Aspartate/aromatic aminotransferase is part of the Pathway/BioSystem: Isoleucine, leucine, valine biosynthesis
Pssm-ID: 441057 Cd Length: 396 Bit Score: 695.69 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1225552194 1 MFKHVEAYPGDPILTLNENFGADPRPHKINLSIGVYLNEAGKMPAMGAVLRAESALAADLGTRPYLPMEGNAAYRAAVRE 80
Cdd:COG1448 1 MFEHLEAAPGDPILGLMEAFRADPRPNKVNLGVGVYKDEQGRTPVLRAVKAAEQRLLETETTKSYLPIEGDAAFNDAVQK 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1225552194 81 LTFGG---AVPADRVAIAQTLGGSGALKVGADFIARYFPKAGVWVSDPTWDNHYSIFAGAGLPVQKYRYYDAATGHVDFP 157
Cdd:COG1448 81 LLFGAdspAVAAGRVATVQTPGGTGALRVGADFLKRAFPDATVWVSDPTWPNHRAIFEAAGLEVKTYPYYDAETGGVDFD 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1225552194 158 GMLAALEALPAGDVVLLHACCHNPTGADLDELQWRELAALVKRRGLLPFFDMAYQGFGKGVDEDAFAIRHFAAEGIPLFA 237
Cdd:COG1448 161 GMLADLKQLPAGDVVLLHGCCHNPTGADLTPEQWQEVAELLKERGLIPFLDIAYQGFGDGLEEDAAGLRLFAEAGPEFLV 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1225552194 238 ATSFSKNFSLYGERCGSLSVVCADAREAGNVLGQLKATIRRNYSSPPTHGARIIARVLDDAALRAEWRAELEGMRTRVAD 317
Cdd:COG1448 241 ASSFSKNFGLYRERVGALSVVAADAEEADRVLSQLKALIRTNYSNPPDHGAAIVATILNDPELRALWEAELAEMRERIKA 320
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1225552194 318 MRAGLYEALRERRPDGDFGYLVKQTGMFSFTGLTPAEVERLREESAVYLVGSGRLCLAALTRRTIAPTADAMARVL 393
Cdd:COG1448 321 MRQQLVDALRAKGPSRDFSFIARQRGMFSYLGLSPEQVDRLREEFGIYMVGSGRINVAGLNESNIDYVAEAIAAVL 396
|
|
| PRK09257 |
PRK09257 |
aromatic amino acid transaminase; |
1-393 |
0e+00 |
|
aromatic amino acid transaminase;
Pssm-ID: 181731 Cd Length: 396 Bit Score: 686.09 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1225552194 1 MFKHVEAYPGDPILTLNENFGADPRPHKINLSIGVYLNEAGKMPAMGAVLRAESALAADLGTRPYLPMEGNAAYRAAVRE 80
Cdd:PRK09257 1 MFEHLEAAPADPILGLMEAFRADPRPDKVNLGVGVYKDEQGRTPVLRAVKKAEARLLETETTKNYLPIEGLAAYRQAVQE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1225552194 81 LTFGGAVP---ADRVAIAQTLGGSGALKVGADFIARYFPKAGVWVSDPTWDNHYSIFAGAGLPVQKYRYYDAATGHVDFP 157
Cdd:PRK09257 81 LLFGADSPalaAGRVATVQTPGGTGALRVGADFLKRAFPDAKVWVSDPTWPNHRAIFEAAGLEVKTYPYYDAATKGLDFD 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1225552194 158 GMLAALEALPAGDVVLLHACCHNPTGADLDELQWRELAALVKRRGLLPFFDMAYQGFGKGVDEDAFAIRHFAAEGIPLFA 237
Cdd:PRK09257 161 AMLADLSQAPAGDVVLLHGCCHNPTGADLTPEQWDELAELLKERGLIPFLDIAYQGFGDGLEEDAYGLRAFAAAGLELLV 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1225552194 238 ATSFSKNFSLYGERCGSLSVVCADAREAGNVLGQLKATIRRNYSSPPTHGARIIARVLDDAALRAEWRAELEGMRTRVAD 317
Cdd:PRK09257 241 ASSFSKNFGLYGERVGALSVVAEDAEEADRVLSQLKATIRTNYSNPPAHGAAIVATILNDPELRAEWEAELEEMRERIKA 320
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1225552194 318 MRAGLYEALRERRPDGDFGYLVKQTGMFSFTGLTPAEVERLREESAVYLVGSGRLCLAALTRRTIAPTADAMARVL 393
Cdd:PRK09257 321 MRQLLVEALKAKGPSRDFDFIARQRGMFSYSGLTPEQVDRLREEFGVYAVGSGRINVAGLNESNIDYVAEAIAAVL 396
|
|
| Aminotran_1_2 |
pfam00155 |
Aminotransferase class I and II; |
26-388 |
4.17e-85 |
|
Aminotransferase class I and II;
Pssm-ID: 395103 [Multi-domain] Cd Length: 351 Bit Score: 263.01 E-value: 4.17e-85
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1225552194 26 PHKINLSIGVYLNEAGKmpamgAVLRAESALAADLGTRPYLPMEGNAAYRAAVRELTFGG-AVPADRVAIAQTLGGSGAL 104
Cdd:pfam00155 1 TDKINLGSNEYLGDTLP-----AVAKAEKDALAGGTRNLYGPTDGHPELREALAKFLGRSpVLKLDREAAVVFGSGAGAN 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1225552194 105 KVGADFIArYFPKAGVWVSDPTWDNHYSIFAGAGLPVQKYRYYDAATGHVDFPGMLAALEALPagdVVLLHACCHNPTGA 184
Cdd:pfam00155 76 IEALIFLL-ANPGDAILVPAPTYASYIRIARLAGGEVVRYPLYDSNDFHLDFDALEAALKEKP---KVVLHTSPHNPTGT 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1225552194 185 DLDELQWRELAALVKRRGLLPFFDMAYQGFGKGvDEDAFAIRHFAAEGIPLFAATSFSKNFSLYGERCGSLSVVCAdare 264
Cdd:pfam00155 152 VATLEELEKLLDLAKEHNILLLVDEAYAGFVFG-SPDAVATRALLAEGPNLLVVGSFSKAFGLAGWRVGYILGNAA---- 226
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1225552194 265 agnVLGQLKATIRRNYSSppTHGARIIARVLDDAALRAEWraeLEGMRTRVADMRAGLYEALRERrpdgDFGYLVKQTGM 344
Cdd:pfam00155 227 ---VISQLRKLARPFYSS--THLQAAAAAALSDPLLVASE---LEEMRQRIKERRDYLRDGLQAA----GLSVLPSQAGF 294
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*.
gi 1225552194 345 FSFTGLTPAEV----ERLREESAVYLV--------GSGRLCLAALTRRTIAPTADA 388
Cdd:pfam00155 295 FLLTGLDPETAkelaQVLLEEVGVYVTpgsspgvpGWLRITVAGGTEEELEELLEA 350
|
|
| AAT_like |
cd00609 |
Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent ... |
29-378 |
5.56e-48 |
|
Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the substrate in four kinds of reactions (1) transamination (movement of amino groups), (2) racemization (redistribution of enantiomers), (3) decarboxylation (removing COOH groups), and (4) various side-chain reactions depending on the enzyme involved. Pyridoxal phosphate (PLP) dependent enzymes were previously classified into alpha, beta and gamma classes, based on the chemical characteristics (carbon atom involved) of the reaction they catalyzed. The availability of several structures allowed a comprehensive analysis of the evolutionary classification of PLP dependent enzymes, and it was found that the functional classification did not always agree with the evolutionary history of these enzymes. The major groups in this CD corresponds to Aspartate aminotransferase a, b and c, Tyrosine, Alanine, Aromatic-amino-acid, Glutamine phenylpyruvate, 1-Aminocyclopropane-1-carboxylate synthase, Histidinol-phosphate, gene products of malY and cobC, Valine-pyruvate aminotransferase and Rhizopine catabolism regulatory protein.
Pssm-ID: 99734 [Multi-domain] Cd Length: 350 Bit Score: 166.75 E-value: 5.56e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1225552194 29 INLSIGVYLNEAGKmpamgAVLRAESALAADLGTRPYLPMEGNAAYRAAVRELTFG-GAVPADRVAIAQTLGGSGALKVG 107
Cdd:cd00609 1 IDLSIGEPDFPPPP-----EVLEALAAAALRAGLLGYYPDPGLPELREAIAEWLGRrGGVDVPPEEIVVTNGAQEALSLL 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1225552194 108 ADFIARyfPKAGVWVSDPTWDNHYSIFAGAGLPVQKYRYYDAatGHVDFPGMLAALEALPAGDVVLLHACcHNPTGADLD 187
Cdd:cd00609 76 LRALLN--PGDEVLVPDPTYPGYEAAARLAGAEVVPVPLDEE--GGFLLDLELLEAAKTPKTKLLYLNNP-NNPTGAVLS 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1225552194 188 ELQWRELAALVKRRGLLPFFDMAYQGFGKgvDEDAFAIRHFAAEGIPLFAATSFSKNFSLYGERCGSLSVVCADAREagn 267
Cdd:cd00609 151 EEELEELAELAKKHGILIISDEAYAELVY--DGEPPPALALLDAYERVIVLRSFSKTFGLPGLRIGYLIAPPEELLE--- 225
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1225552194 268 vlgQLKATIRRNYSSPPTHGARIIARVLDDAAlraewrAELEGMRTRVADMRAGLYEALRERRPDgdfGYLVKQTGMFSF 347
Cdd:cd00609 226 ---RLKKLLPYTTSGPSTLSQAAAAAALDDGE------EHLEELRERYRRRRDALLEALKELGPL---VVVKPSGGFFLW 293
|
330 340 350 360
....*....|....*....|....*....|....*....|....*
gi 1225552194 348 TGLTP----AEVERLREESAVYLV----------GSGRLCLAALT 378
Cdd:cd00609 294 LDLPEgddeEFLERLLLEAGVVVRpgsafgeggeGFVRLSFATPE 338
|
|
| DAPAT_plant |
TIGR03542 |
LL-diaminopimelate aminotransferase; This clade of the pfam00155 superfamily of ... |
16-258 |
3.06e-06 |
|
LL-diaminopimelate aminotransferase; This clade of the pfam00155 superfamily of aminotransferases includes several which are adjacent to elements of the lysine biosynthesis via diaminopimelate pathway (GenProp0125). This clade includes characterized species in plants and Chlamydia. Every member of this clade is from a genome which possesses most of the lysine biosynthesis pathway but lacks any of the known succinylases, desuccinylases, acetylases or deacetylases typical of the acylated versions of this pathway nor do they have the direct, NADPH-dependent enzyme (ddh).
Pssm-ID: 163316 Cd Length: 402 Bit Score: 48.95 E-value: 3.06e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1225552194 16 LNENFGADPRPHKINLSIGvylneAGKMPAMGAVLRAESALAADLGT----RPYLPMEGNAAYRAAVRELTFGGAVPADR 91
Cdd:TIGR03542 23 VAEFRKKNPSADIIRLGIG-----DTTQPLPASVIEAFHNAVDELASpetfRGYGPEQGYPFLREAIAENDYRGRIDPEE 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1225552194 92 VAIaqtlggSGALKVGADFIARYF-PKAGVWVSDPTWD--NHYSIFAGAGLPVQKYRYYD-----AATGHVDFpgmLAAL 163
Cdd:TIGR03542 98 IFI------SDGAKCDVFRLQSLFgPDNTVAVQDPVYPayLDSNVMAGRAGVLDDDGRYSkitylPCTAENNF---IPEL 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1225552194 164 EALPAGDVVLLhacC--HNPTGADLDELQWRELAALVKRRGLLPFFDMAYQGFgkgVDEDAFAIRHFAAEGIPLFAA--T 239
Cdd:TIGR03542 169 PEEPHIDIIYL---CspNNPTGTVLTKEQLKELVDYANEHGSLILFDAAYSAF---ISDPSLPHSIFEIPGARFCAIefR 242
|
250
....*....|....*....
gi 1225552194 240 SFSKNFSLYGERCGsLSVV 258
Cdd:TIGR03542 243 SFSKTAGFTGVRLG-WTVV 260
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| TyrB |
COG1448 |
Aspartate/aromatic aminotransferase [Amino acid transport and metabolism]; Aspartate/aromatic ... |
1-393 |
0e+00 |
|
Aspartate/aromatic aminotransferase [Amino acid transport and metabolism]; Aspartate/aromatic aminotransferase is part of the Pathway/BioSystem: Isoleucine, leucine, valine biosynthesis
Pssm-ID: 441057 Cd Length: 396 Bit Score: 695.69 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1225552194 1 MFKHVEAYPGDPILTLNENFGADPRPHKINLSIGVYLNEAGKMPAMGAVLRAESALAADLGTRPYLPMEGNAAYRAAVRE 80
Cdd:COG1448 1 MFEHLEAAPGDPILGLMEAFRADPRPNKVNLGVGVYKDEQGRTPVLRAVKAAEQRLLETETTKSYLPIEGDAAFNDAVQK 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1225552194 81 LTFGG---AVPADRVAIAQTLGGSGALKVGADFIARYFPKAGVWVSDPTWDNHYSIFAGAGLPVQKYRYYDAATGHVDFP 157
Cdd:COG1448 81 LLFGAdspAVAAGRVATVQTPGGTGALRVGADFLKRAFPDATVWVSDPTWPNHRAIFEAAGLEVKTYPYYDAETGGVDFD 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1225552194 158 GMLAALEALPAGDVVLLHACCHNPTGADLDELQWRELAALVKRRGLLPFFDMAYQGFGKGVDEDAFAIRHFAAEGIPLFA 237
Cdd:COG1448 161 GMLADLKQLPAGDVVLLHGCCHNPTGADLTPEQWQEVAELLKERGLIPFLDIAYQGFGDGLEEDAAGLRLFAEAGPEFLV 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1225552194 238 ATSFSKNFSLYGERCGSLSVVCADAREAGNVLGQLKATIRRNYSSPPTHGARIIARVLDDAALRAEWRAELEGMRTRVAD 317
Cdd:COG1448 241 ASSFSKNFGLYRERVGALSVVAADAEEADRVLSQLKALIRTNYSNPPDHGAAIVATILNDPELRALWEAELAEMRERIKA 320
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1225552194 318 MRAGLYEALRERRPDGDFGYLVKQTGMFSFTGLTPAEVERLREESAVYLVGSGRLCLAALTRRTIAPTADAMARVL 393
Cdd:COG1448 321 MRQQLVDALRAKGPSRDFSFIARQRGMFSYLGLSPEQVDRLREEFGIYMVGSGRINVAGLNESNIDYVAEAIAAVL 396
|
|
| PRK09257 |
PRK09257 |
aromatic amino acid transaminase; |
1-393 |
0e+00 |
|
aromatic amino acid transaminase;
Pssm-ID: 181731 Cd Length: 396 Bit Score: 686.09 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1225552194 1 MFKHVEAYPGDPILTLNENFGADPRPHKINLSIGVYLNEAGKMPAMGAVLRAESALAADLGTRPYLPMEGNAAYRAAVRE 80
Cdd:PRK09257 1 MFEHLEAAPADPILGLMEAFRADPRPDKVNLGVGVYKDEQGRTPVLRAVKKAEARLLETETTKNYLPIEGLAAYRQAVQE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1225552194 81 LTFGGAVP---ADRVAIAQTLGGSGALKVGADFIARYFPKAGVWVSDPTWDNHYSIFAGAGLPVQKYRYYDAATGHVDFP 157
Cdd:PRK09257 81 LLFGADSPalaAGRVATVQTPGGTGALRVGADFLKRAFPDAKVWVSDPTWPNHRAIFEAAGLEVKTYPYYDAATKGLDFD 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1225552194 158 GMLAALEALPAGDVVLLHACCHNPTGADLDELQWRELAALVKRRGLLPFFDMAYQGFGKGVDEDAFAIRHFAAEGIPLFA 237
Cdd:PRK09257 161 AMLADLSQAPAGDVVLLHGCCHNPTGADLTPEQWDELAELLKERGLIPFLDIAYQGFGDGLEEDAYGLRAFAAAGLELLV 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1225552194 238 ATSFSKNFSLYGERCGSLSVVCADAREAGNVLGQLKATIRRNYSSPPTHGARIIARVLDDAALRAEWRAELEGMRTRVAD 317
Cdd:PRK09257 241 ASSFSKNFGLYGERVGALSVVAEDAEEADRVLSQLKATIRTNYSNPPAHGAAIVATILNDPELRAEWEAELEEMRERIKA 320
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1225552194 318 MRAGLYEALRERRPDGDFGYLVKQTGMFSFTGLTPAEVERLREESAVYLVGSGRLCLAALTRRTIAPTADAMARVL 393
Cdd:PRK09257 321 MRQLLVEALKAKGPSRDFDFIARQRGMFSYSGLTPEQVDRLREEFGVYAVGSGRINVAGLNESNIDYVAEAIAAVL 396
|
|
| PTZ00376 |
PTZ00376 |
aspartate aminotransferase; Provisional |
2-393 |
3.01e-176 |
|
aspartate aminotransferase; Provisional
Pssm-ID: 240390 Cd Length: 404 Bit Score: 496.75 E-value: 3.01e-176
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1225552194 2 FKHVEAYPGDPILTLNENFGADPRPHKINLSIGVYLNEAGKMPAMGAVLRAESALAADLGTRPYLPMEGNAAYRAAVREL 81
Cdd:PTZ00376 5 FSQVPLGPPDPILGLAAAFKADPSPSKVNLGIGAYRDENGKPYVLESVRKAEKIIAEKNLDKEYLPIEGLQSFIEAAQKL 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1225552194 82 TFGGAVPA---DRVAIAQTLGGSGALKVGADFIARYFPKAG-VWVSDPTWDNHYSIFAGAGLPVQKYRYYDAATGHVDFP 157
Cdd:PTZ00376 85 LFGEASYAlaeKRIATVQALSGTGALRLGFEFLKRFLPAGTtVYVSNPTWPNHVNIFKSAGLNVKEYRYYDPKTKGLDFD 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1225552194 158 GMLAALEALPAGDVVLLHACCHNPTGADLDELQWRELAALVKRRGLLPFFDMAYQGFGKG-VDEDAFAIRHFAAEGIPLF 236
Cdd:PTZ00376 165 GMLEDLRTAPNGSVVLLHACAHNPTGVDPTEEQWKEIADVMKRKNLIPFFDMAYQGFASGdLDKDAYAIRLFAERGVEFL 244
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1225552194 237 AATSFSKNFSLYGERCGSLSVVCADAREAGNVLGQLKATIRRNYSSPPTHGARIIARVLDDAALRAEWRAELEGMRTRVA 316
Cdd:PTZ00376 245 VAQSFSKNMGLYGERIGALHIVCANKEEAANVLSQLKLIIRPMYSSPPIHGARIADRILSDPELRAEWLSELKEMSGRIQ 324
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1225552194 317 DMRAGLYEALRERRPDGDFGYLVKQTGMFSFTGLTPAEVERLREESAVYLVGSGRLCLAALTRRTIAPTADAMARVL 393
Cdd:PTZ00376 325 NMRQLLYDELKALGSPGDWEHIINQIGMFSFTGLTKEQVERLIEKYHIYLLDNGRISVAGLTSKNVDYVAEAIHDVV 401
|
|
| PLN02397 |
PLN02397 |
aspartate transaminase |
2-392 |
1.04e-163 |
|
aspartate transaminase
Pssm-ID: 215222 Cd Length: 423 Bit Score: 465.59 E-value: 1.04e-163
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1225552194 2 FKHVEAYPGDPILTLNENFGADPRPHKINLSIGVYLNEAGKMPAMGAVLRAESALAADLGTRPYLPMEGNAAYRAAVREL 81
Cdd:PLN02397 24 FEHVEPAPPDPILGVTEAFLADPSPVKLNLGVGAYRTEEGKPVVLNVVRKAEQRLLAGSRNKEYLPIEGLAEFNKLSAKL 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1225552194 82 TFGGAVPA---DRVAIAQTLGGSGALKVGADFIARYFPKAGVWVSDPTWDNHYSIFAGAGLPVQKYRYYDAATGHVDFPG 158
Cdd:PLN02397 104 AYGADSPAikeNRVATVQCLSGTGSLRLGAEFLARFYPGSTIYIPNPTWGNHHNIFRDAGVPVRTYRYYDPKTRGLDFDG 183
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1225552194 159 MLAALEALPAGDVVLLHACCHNPTGADLDELQWRELAALVKRRGLLPFFDMAYQGFGKG-VDEDAFAIRHFAAEGIPLFA 237
Cdd:PLN02397 184 LLEDLKAAPDGSFVLLHACAHNPTGVDPTPEQWEQISDLIKSKNHLPFFDSAYQGFASGdLDADAQSVRMFVEDGHEILV 263
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1225552194 238 ATSFSKNFSLYGERCGSLSVVCADAREAGNVLGQLKATIRRNYSSPPTHGARIIARVLDDAALRAEWRAELEGMRTRVAD 317
Cdd:PLN02397 264 AQSYAKNMGLYGERVGALSVVCKSADVAVRVKSQLKLIARPMYSNPPIHGASIVATILGDPELFSEWTKELKGMADRIIS 343
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1225552194 318 MRAGLYEALRERRPDGDFGYLVKQTGMFSFTGLTPAEVERLREESAVYLVGSGRLCLAALTRRTIAPTADAMARV 392
Cdd:PLN02397 344 MRQKLYDALEARGSPGDWSHITKQIGMFSFTGLNKEQVDRMTKEYHIYMTRDGRISMAGLSSKNVPYLADAIHAV 418
|
|
| Aminotran_1_2 |
pfam00155 |
Aminotransferase class I and II; |
26-388 |
4.17e-85 |
|
Aminotransferase class I and II;
Pssm-ID: 395103 [Multi-domain] Cd Length: 351 Bit Score: 263.01 E-value: 4.17e-85
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1225552194 26 PHKINLSIGVYLNEAGKmpamgAVLRAESALAADLGTRPYLPMEGNAAYRAAVRELTFGG-AVPADRVAIAQTLGGSGAL 104
Cdd:pfam00155 1 TDKINLGSNEYLGDTLP-----AVAKAEKDALAGGTRNLYGPTDGHPELREALAKFLGRSpVLKLDREAAVVFGSGAGAN 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1225552194 105 KVGADFIArYFPKAGVWVSDPTWDNHYSIFAGAGLPVQKYRYYDAATGHVDFPGMLAALEALPagdVVLLHACCHNPTGA 184
Cdd:pfam00155 76 IEALIFLL-ANPGDAILVPAPTYASYIRIARLAGGEVVRYPLYDSNDFHLDFDALEAALKEKP---KVVLHTSPHNPTGT 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1225552194 185 DLDELQWRELAALVKRRGLLPFFDMAYQGFGKGvDEDAFAIRHFAAEGIPLFAATSFSKNFSLYGERCGSLSVVCAdare 264
Cdd:pfam00155 152 VATLEELEKLLDLAKEHNILLLVDEAYAGFVFG-SPDAVATRALLAEGPNLLVVGSFSKAFGLAGWRVGYILGNAA---- 226
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1225552194 265 agnVLGQLKATIRRNYSSppTHGARIIARVLDDAALRAEWraeLEGMRTRVADMRAGLYEALRERrpdgDFGYLVKQTGM 344
Cdd:pfam00155 227 ---VISQLRKLARPFYSS--THLQAAAAAALSDPLLVASE---LEEMRQRIKERRDYLRDGLQAA----GLSVLPSQAGF 294
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*.
gi 1225552194 345 FSFTGLTPAEV----ERLREESAVYLV--------GSGRLCLAALTRRTIAPTADA 388
Cdd:pfam00155 295 FLLTGLDPETAkelaQVLLEEVGVYVTpgsspgvpGWLRITVAGGTEEELEELLEA 350
|
|
| AAT_like |
cd00609 |
Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent ... |
29-378 |
5.56e-48 |
|
Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the substrate in four kinds of reactions (1) transamination (movement of amino groups), (2) racemization (redistribution of enantiomers), (3) decarboxylation (removing COOH groups), and (4) various side-chain reactions depending on the enzyme involved. Pyridoxal phosphate (PLP) dependent enzymes were previously classified into alpha, beta and gamma classes, based on the chemical characteristics (carbon atom involved) of the reaction they catalyzed. The availability of several structures allowed a comprehensive analysis of the evolutionary classification of PLP dependent enzymes, and it was found that the functional classification did not always agree with the evolutionary history of these enzymes. The major groups in this CD corresponds to Aspartate aminotransferase a, b and c, Tyrosine, Alanine, Aromatic-amino-acid, Glutamine phenylpyruvate, 1-Aminocyclopropane-1-carboxylate synthase, Histidinol-phosphate, gene products of malY and cobC, Valine-pyruvate aminotransferase and Rhizopine catabolism regulatory protein.
Pssm-ID: 99734 [Multi-domain] Cd Length: 350 Bit Score: 166.75 E-value: 5.56e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1225552194 29 INLSIGVYLNEAGKmpamgAVLRAESALAADLGTRPYLPMEGNAAYRAAVRELTFG-GAVPADRVAIAQTLGGSGALKVG 107
Cdd:cd00609 1 IDLSIGEPDFPPPP-----EVLEALAAAALRAGLLGYYPDPGLPELREAIAEWLGRrGGVDVPPEEIVVTNGAQEALSLL 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1225552194 108 ADFIARyfPKAGVWVSDPTWDNHYSIFAGAGLPVQKYRYYDAatGHVDFPGMLAALEALPAGDVVLLHACcHNPTGADLD 187
Cdd:cd00609 76 LRALLN--PGDEVLVPDPTYPGYEAAARLAGAEVVPVPLDEE--GGFLLDLELLEAAKTPKTKLLYLNNP-NNPTGAVLS 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1225552194 188 ELQWRELAALVKRRGLLPFFDMAYQGFGKgvDEDAFAIRHFAAEGIPLFAATSFSKNFSLYGERCGSLSVVCADAREagn 267
Cdd:cd00609 151 EEELEELAELAKKHGILIISDEAYAELVY--DGEPPPALALLDAYERVIVLRSFSKTFGLPGLRIGYLIAPPEELLE--- 225
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1225552194 268 vlgQLKATIRRNYSSPPTHGARIIARVLDDAAlraewrAELEGMRTRVADMRAGLYEALRERRPDgdfGYLVKQTGMFSF 347
Cdd:cd00609 226 ---RLKKLLPYTTSGPSTLSQAAAAAALDDGE------EHLEELRERYRRRRDALLEALKELGPL---VVVKPSGGFFLW 293
|
330 340 350 360
....*....|....*....|....*....|....*....|....*
gi 1225552194 348 TGLTP----AEVERLREESAVYLV----------GSGRLCLAALT 378
Cdd:cd00609 294 LDLPEgddeEFLERLLLEAGVVVRpgsafgeggeGFVRLSFATPE 338
|
|
| AspB |
COG0436 |
Aspartate/methionine/tyrosine aminotransferase [Amino acid transport and metabolism]; ... |
29-395 |
5.79e-14 |
|
Aspartate/methionine/tyrosine aminotransferase [Amino acid transport and metabolism]; Aspartate/methionine/tyrosine aminotransferase is part of the Pathway/BioSystem: Isoleucine, leucine, valine biosynthesis
Pssm-ID: 440205 [Multi-domain] Cd Length: 387 Bit Score: 72.86 E-value: 5.79e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1225552194 29 INLSIGvylnEAGKMPAMGAVLRAESALAAdlGTRPYLPMEGNAAYRAAVRELT---FGGAVPADRVAIaqTLGGSGALk 105
Cdd:COG0436 33 IDLGIG----EPDFPTPDHIREAAIEALDD--GVTGYTPSAGIPELREAIAAYYkrrYGVDLDPDEILV--TNGAKEAL- 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1225552194 106 vgaDFIARYFPKAG--VWVSDPTWDNHYSI--FAGAglpvqKYRYYDAATGHvDFPGMLAALEAL--PAGDVVLLhacC- 178
Cdd:COG0436 104 ---ALALLALLNPGdeVLVPDPGYPSYRAAvrLAGG-----KPVPVPLDEEN-GFLPDPEALEAAitPRTKAIVL---Ns 171
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1225552194 179 -HNPTGADLDELQWRELAALVKRRGLLPFFDMAYQGFG------------KGVDEDAFAIrhfaaegiplfaaTSFSKNF 245
Cdd:COG0436 172 pNNPTGAVYSREELEALAELAREHDLLVISDEIYEELVydgaehvsilslPGLKDRTIVI-------------NSFSKSY 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1225552194 246 SLYGERCGSLsVVCADAREAgnvLGQLKATIRrnySSPPTHGARIIArvlddAALRAEwRAELEGMRTRVADMRAGLYEA 325
Cdd:COG0436 239 AMTGWRIGYA-VGPPELIAA---LLKLQSNLT---SCAPTPAQYAAA-----AALEGP-QDYVEEMRAEYRRRRDLLVEG 305
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1225552194 326 LRE-----RRPDGDFgYL-VKqtgmFSFTGLTPAE-VERLREESAVYLV-GSG---------RLCLAAlTRRTIAPTADA 388
Cdd:COG0436 306 LNEiglsvVKPEGAF-YLfAD----VPELGLDSEEfAERLLEEAGVAVVpGSAfgpagegyvRISYAT-SEERLEEALER 379
|
....*..
gi 1225552194 389 MARVLGR 395
Cdd:COG0436 380 LARFLER 386
|
|
| ARO8 |
COG1167 |
DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain ... |
45-396 |
1.78e-11 |
|
DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain [Transcription, Amino acid transport and metabolism]; DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain is part of the Pathway/BioSystem: Lysine biosynthesis
Pssm-ID: 440781 [Multi-domain] Cd Length: 471 Bit Score: 65.24 E-value: 1.78e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1225552194 45 AMGAVLRAESALAADlgtrpYLPMEGNAAYRAAVRE--LTFGGAVPADRVAIaqTLGGSGALkvgaDFIARYFPKAG--V 120
Cdd:COG1167 129 ALRRALRRLPPALLG-----YGDPQGLPELREAIARylARRGVPASPDQILI--TSGAQQAL----DLALRALLRPGdtV 197
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1225552194 121 WVSDPTWDNHYSIFAGAGL---PVQkyryydaatghVDFPGM-LAALEAL---PAGDVVLLHACCHNPTGADLDELQWRE 193
Cdd:COG1167 198 AVESPTYPGALAALRAAGLrlvPVP-----------VDEDGLdLDALEAAlrrHRPRAVYVTPSHQNPTGATMSLERRRA 266
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1225552194 194 LAALVKRRGLLPFFDMAYQGFgkgvdedafairHFAAEGIPLFAA----------TSFSKNFS--LygeRCGSLSVvcad 261
Cdd:COG1167 267 LLELARRHGVPIIEDDYDSEL------------RYDGRPPPPLAAldapgrviyiGSFSKTLApgL---RLGYLVA---- 327
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1225552194 262 areAGNVLGQLKATIRRNYSSPPTHGARIIARVLDDaalrAEWRAELEGMRTRVADMRAGLYEALRERRPDGdFGYLVKQ 341
Cdd:COG1167 328 ---PGRLIERLARLKRATDLGTSPLTQLALAEFLES----GHYDRHLRRLRREYRARRDLLLAALARHLPDG-LRVTGPP 399
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1225552194 342 TGMFsFTGLTPAEV------ERLREE------SAVYLVGSG-----RLCLAALTRRTIAPTADAMARVLGRR 396
Cdd:COG1167 400 GGLH-LWLELPEGVdaealaAAALARgilvapGSAFSADGPprnglRLGFGAPSEEELEEALRRLAELLREL 470
|
|
| PRK08960 |
PRK08960 |
pyridoxal phosphate-dependent aminotransferase; |
52-346 |
1.58e-07 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 181595 Cd Length: 387 Bit Score: 52.75 E-value: 1.58e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1225552194 52 AESALAAdlGTRPYLPMEGNAAYRAAVREL---TFGGAVPADRVAIaqTLGGSGALKVGADFIARyfPKAGVWVSDPTW- 127
Cdd:PRK08960 54 GQAALAA--GHTRYTAARGLPALREAIAGFyaqRYGVDVDPERILV--TPGGSGALLLASSLLVD--PGKHWLLADPGYp 127
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1225552194 128 -DNHY-SIFAGA--GLPVQKYRYYDAATGHVDF---PGMLAALEALPAgdvvllhacchNPTGADLDELQWRELAALVKR 200
Cdd:PRK08960 128 cNRHFlRLVEGAaqLVPVGPDSRYQLTPALVERhwnADTVGALVASPA-----------NPTGTLLSRDELAALSQALRA 196
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1225552194 201 RGLLPFFDMAYQGFGKG--------VDEDAFAIrhfaaegiplfaaTSFSKNFSLYGERCGSLsVVCADAREAGNVLGQl 272
Cdd:PRK08960 197 RGGHLVVDEIYHGLTYGvdaasvleVDDDAFVL-------------NSFSKYFGMTGWRLGWL-VAPPAAVPELEKLAQ- 261
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1225552194 273 katirRNYSSPPThgariIARVLDDAALRAEWRAELEGMRTRVADMRAGLYEALRE------RRPDGDFgYLVKQTGMFS 346
Cdd:PRK08960 262 -----NLYISAST-----PAQHAALACFEPETLAILEARRAEFARRRDFLLPALRElgfgiaVEPQGAF-YLYADISAFG 330
|
|
| AAT_I |
cd01494 |
Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP) ... |
75-257 |
6.32e-07 |
|
Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the substrate in four kinds of reactions (1) transamination (movement of amino groups), (2) racemization (redistribution of enantiomers), (3) decarboxylation (removing COOH groups), and (4) various side-chain reactions depending on the enzyme involved. Pyridoxal phosphate (PLP) dependent enzymes were previously classified into alpha, beta and gamma classes, based on the chemical characteristics (carbon atom involved) of the reaction they catalyzed. The availability of several structures allowed a comprehensive analysis of the evolutionary classification of PLP dependent enzymes, and it was found that the functional classification did not always agree with the evolutionary history of these enzymes. Structure and sequence analysis has revealed that the PLP dependent enzymes can be classified into four major groups of different evolutionary origin: aspartate aminotransferase superfamily (fold type I), tryptophan synthase beta superfamily (fold type II), alanine racemase superfamily (fold type III), and D-amino acid superfamily (fold type IV) and Glycogen phophorylase family (fold type V).
Pssm-ID: 99742 [Multi-domain] Cd Length: 170 Bit Score: 48.92 E-value: 6.32e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1225552194 75 RAAVRELTFGGAVpadrvAIAQTLGGSGALKVGADFIARyfPKAGVWVSDPTWDNHYSIFA---GAGL-PVQKYRYYDAA 150
Cdd:cd01494 6 EEKLARLLQPGND-----KAVFVPSGTGANEAALLALLG--PGDEVIVDANGHGSRYWVAAelaGAKPvPVPVDDAGYGG 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1225552194 151 TGHVDFPgmlaalEALPAGDVVLLHAccHNPTGADLDELQWRELAALVKRRGLLPFFDMAYQGFGkgvdedAFAIRHFAA 230
Cdd:cd01494 79 LDVAILE------ELKAKPNVALIVI--TPNTTSGGVLVPLKEIRKIAKEYGILLLVDAASAGGA------SPAPGVLIP 144
|
170 180
....*....|....*....|....*..
gi 1225552194 231 EGIPLFAATSFSKNFSlyGERCGSLSV 257
Cdd:cd01494 145 EGGADVVTFSLHKNLG--GEGGGVVIV 169
|
|
| HisC |
COG0079 |
Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase [Amino acid ... |
51-328 |
1.04e-06 |
|
Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase [Amino acid transport and metabolism]; Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase is part of the Pathway/BioSystem: Cobalamine/B12 biosynthesis
Pssm-ID: 439849 [Multi-domain] Cd Length: 341 Bit Score: 50.13 E-value: 1.04e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1225552194 51 RAESALAADLGTRPYLPMEGNAAYRAAVRELtFGgaVPADRVAIAqtlGGSGALkvgADFIARYFPKAG--VWVSDPTWD 128
Cdd:COG0079 30 KVLEAIAAALDALNRYPDPDATALREALAEY-YG--VPPEQVLVG---NGSDEL---IQLLARAFLGPGdeVLVPEPTFS 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1225552194 129 NHYSIFAGAGLPVQKYRYydAATGHVDFPGMLAALEALPagDVVLLhacC--HNPTGADLDELQWRELAALVKRRGLLpF 206
Cdd:COG0079 101 EYPIAARAAGAEVVEVPL--DEDFSLDLDALLAAITERT--DLVFL---CnpNNPTGTLLPREELEALLEALPADGLV-V 172
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1225552194 207 FDMAYQGFGKGVDEdafairhfaaeGIPLFAAT-------SFSKNFSLYGERCGslsVVCADAreagnvlgQLKATIRR- 278
Cdd:COG0079 173 VDEAYAEFVPEEDS-----------ALPLLARYpnlvvlrTFSKAYGLAGLRLG---YAIASP--------ELIAALRRv 230
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....
gi 1225552194 279 ----NYSSPpthgARIIARvlddAALRAewRAELEGMRTRVADMRAGLYEALRE 328
Cdd:COG0079 231 rgpwNVNSL----AQAAAL----AALED--RAYLEETRARLRAERERLAAALRA 274
|
|
| DAPAT_plant |
TIGR03542 |
LL-diaminopimelate aminotransferase; This clade of the pfam00155 superfamily of ... |
16-258 |
3.06e-06 |
|
LL-diaminopimelate aminotransferase; This clade of the pfam00155 superfamily of aminotransferases includes several which are adjacent to elements of the lysine biosynthesis via diaminopimelate pathway (GenProp0125). This clade includes characterized species in plants and Chlamydia. Every member of this clade is from a genome which possesses most of the lysine biosynthesis pathway but lacks any of the known succinylases, desuccinylases, acetylases or deacetylases typical of the acylated versions of this pathway nor do they have the direct, NADPH-dependent enzyme (ddh).
Pssm-ID: 163316 Cd Length: 402 Bit Score: 48.95 E-value: 3.06e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1225552194 16 LNENFGADPRPHKINLSIGvylneAGKMPAMGAVLRAESALAADLGT----RPYLPMEGNAAYRAAVRELTFGGAVPADR 91
Cdd:TIGR03542 23 VAEFRKKNPSADIIRLGIG-----DTTQPLPASVIEAFHNAVDELASpetfRGYGPEQGYPFLREAIAENDYRGRIDPEE 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1225552194 92 VAIaqtlggSGALKVGADFIARYF-PKAGVWVSDPTWD--NHYSIFAGAGLPVQKYRYYD-----AATGHVDFpgmLAAL 163
Cdd:TIGR03542 98 IFI------SDGAKCDVFRLQSLFgPDNTVAVQDPVYPayLDSNVMAGRAGVLDDDGRYSkitylPCTAENNF---IPEL 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1225552194 164 EALPAGDVVLLhacC--HNPTGADLDELQWRELAALVKRRGLLPFFDMAYQGFgkgVDEDAFAIRHFAAEGIPLFAA--T 239
Cdd:TIGR03542 169 PEEPHIDIIYL---CspNNPTGTVLTKEQLKELVDYANEHGSLILFDAAYSAF---ISDPSLPHSIFEIPGARFCAIefR 242
|
250
....*....|....*....
gi 1225552194 240 SFSKNFSLYGERCGsLSVV 258
Cdd:TIGR03542 243 SFSKTAGFTGVRLG-WTVV 260
|
|
| PRK06836 |
PRK06836 |
pyridoxal phosphate-dependent aminotransferase; |
65-338 |
5.16e-06 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 180720 Cd Length: 394 Bit Score: 48.27 E-value: 5.16e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1225552194 65 YLPMEGNAAYRAAVREL---TFGGAVPADRVAIaqTLGGSGALKV--------GADFI--ARYFPKAGVWVsdptwDNHy 131
Cdd:PRK06836 69 YMPNAGYPEVREAIAESlnrRFGTPLTADHIVM--TCGAAGALNValkailnpGDEVIvfAPYFVEYRFYV-----DNH- 140
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1225552194 132 sifaGAGLPVqkyryydAATGHVDFPGMLAALEAL--PAGDVVLLHACcHNPTGADLDELQWRELAALVKRRGllpffdm 209
Cdd:PRK06836 141 ----GGKLVV-------VPTDTDTFQPDLDALEAAitPKTKAVIINSP-NNPTGVVYSEETLKALAALLEEKS------- 201
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1225552194 210 ayQGFGKGV----DEdafAIRHFAAEGI---PLFAA-------TSFSKNFSLYGERCGSLSV---------VCADAREAG 266
Cdd:PRK06836 202 --KEYGRPIylisDE---PYREIVYDGAevpYIFKYydnsivvYSFSKSLSLPGERIGYIAVnpemedaddLVAALVFAN 276
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1225552194 267 NVLGqlkatirrnYSSPPTHGARIIARVLDDaalraewRAELEGMRTRvadmRAGLYEALRE-----RRPDGDFgYL 338
Cdd:PRK06836 277 RILG---------FVNAPALMQRVVAKCLDA-------TVDVSIYKRN----RDLLYDGLTElgfecVKPQGAF-YL 332
|
|
| PRK07550 |
PRK07550 |
aminotransferase; |
44-322 |
2.48e-05 |
|
aminotransferase;
Pssm-ID: 181026 [Multi-domain] Cd Length: 386 Bit Score: 46.10 E-value: 2.48e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1225552194 44 PAMGAVLRAESALAADLGTRPYLPMEGNAAYRAAV----RELtFGGAVPADRVAIaqTLGGSGALKVGADFIARyfpkAG 119
Cdd:PRK07550 42 PPPPELLRALAEAAADPAAHLYGPVEGLPELREAYaahySRL-YGAAISPEQVHI--TSGCNQAFWAAMVTLAG----AG 114
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1225552194 120 --VWVSDPTWDNHYSIFAGAGL-PVqkYRYYDAATGHVDFPGMLAALeaLPAGDVVLLHACCHNPTGADLDELQWRELAA 196
Cdd:PRK07550 115 deVILPLPWYFNHKMWLDMLGIrPV--YLPCDEGPGLLPDPAAAEAL--ITPRTRAIALVTPNNPTGVVYPPELLHELYD 190
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1225552194 197 LVKRRGLLPFFDMAYQGF--GKGVDEDAFAIRHFAAEGIPLFaatSFSKNFSLYGERCGSLSVVCADAREAGNVLGQLKA 274
Cdd:PRK07550 191 LARRHGIALILDETYRDFdsGGGAPHDLFADPDWDDTLVHLY---SFSKSYALTGHRVGAVVASPARIAEIEKFMDTVAI 267
|
250 260 270 280
....*....|....*....|....*....|....*....|....*....
gi 1225552194 275 TIRRNysspPTHGARIIARVLDDaalraeWRAELEGMRTRVAD-MRAGL 322
Cdd:PRK07550 268 CAPRI----GQIAVAWGLPNLAD------WRAGNRAEIARRRDaFRAVF 306
|
|
| PRK08637 |
PRK08637 |
hypothetical protein; Provisional |
27-324 |
5.92e-05 |
|
hypothetical protein; Provisional
Pssm-ID: 181512 Cd Length: 388 Bit Score: 44.95 E-value: 5.92e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1225552194 27 HKINLSIGVYLNEAGKM--PAMGAVLraeSALAADlGTRPYLPMEGNAAYRAAVRELTF-------GGAVPADRVAIAQT 97
Cdd:PRK08637 4 TKYNATIGMATEKGGPMylSSLQDLL---NDLTPD-EIFPYAPPQGIPELRDLWQEKMLrenpslsGKKMSLPIVTNALT 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1225552194 98 LGgsgaLKVGADFiaryFPKAG--VWVSDPTWDNHYSIFAGA-GLPVQKYRYYDAAtGHVDFPGMLAALEALPAGD-VVL 173
Cdd:PRK08637 80 HG----LSLVADL----FVDQGdtVLLPDHNWGNYKLTFNTRrGAEIVTYPIFDED-GGFDTDALKEALQAAYNKGkVIV 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1225552194 174 LHACCHNPTGADLDELQWRELAALVK---RRG--LLPFFDMAYQG-----------FGK--GVDEDAFAIRhfaaegipL 235
Cdd:PRK08637 151 ILNFPNNPTGYTPTEKEATAIVEAIKelaDAGtkVVAVVDDAYFGlfyedsykeslFAAlaNLHSNILAVK--------L 222
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1225552194 236 FAATsfsKNFSLYGERCGSLSvvCAD-AREAGNVLGQL----KATIRRNYSSPPTHGARIIARVLDDAALRAEWRAELEG 310
Cdd:PRK08637 223 DGAT---KEEFVWGFRVGFIT--FGTkAGSSQTVKEALekkvKGLIRSNISNGPHPSQSAVLRALNSPEFDKEKQEKFQI 297
|
330
....*....|....
gi 1225552194 311 MRTRVADMRAGLYE 324
Cdd:PRK08637 298 LKERYEKTKEVLYD 311
|
|
| PRK07324 |
PRK07324 |
transaminase; Validated |
55-253 |
1.51e-04 |
|
transaminase; Validated
Pssm-ID: 235989 Cd Length: 373 Bit Score: 43.39 E-value: 1.51e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1225552194 55 ALAADLGTRP--YLPMEGNAAYRAAVRELTfggavpaDRVAIAQTLGGSGAlkVGADFIARYF---PKAGVWVSDPTWDN 129
Cdd:PRK07324 46 AFYQELGQKKltYGWIEGSPEFKEAVASLY-------QNVKPENILQTNGA--TGANFLVLYAlvePGDHVISVYPTYQQ 116
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1225552194 130 HYSIFAGAGLPVQKYRYYDAAtghvDFPGMLAALEAL--PAGDVVLLHACcHNPTGADLDELQWRELAALVKRRGLLPFF 207
Cdd:PRK07324 117 LYDIPESLGAEVDYWQLKEEN----GWLPDLDELRRLvrPNTKLICINNA-NNPTGALMDRAYLEEIVEIARSVDAYVLS 191
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 1225552194 208 DMAYQGFGKgvDEDAFAIRHFAAEGIplfAATSFSKNFSLYGERCG 253
Cdd:PRK07324 192 DEVYRPLDE--DGSTPSIADLYEKGI---STNSMSKTYSLPGIRVG 232
|
|
| hisC |
TIGR01141 |
histidinol-phosphate aminotransferase; Alternate names: histidinol-phosphate transaminase; ... |
109-253 |
4.60e-04 |
|
histidinol-phosphate aminotransferase; Alternate names: histidinol-phosphate transaminase; imidazole acetol-phosphate transaminase Histidinol-phosphate aminotransferase is a pyridoxal-phosphate dependent enzyme. [Amino acid biosynthesis, Histidine family]
Pssm-ID: 273467 Cd Length: 350 Bit Score: 41.87 E-value: 4.60e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1225552194 109 DFIARYF--PKAGVWVSDPTWDnHYSIFA-GAGLPVQKYRYYDaatghvDFPGMLAALEALPAGDVVLLHACC-HNPTGA 184
Cdd:TIGR01141 86 DLLIRAFlePGDAVLVPPPTYS-MYEISAkIHGAEVVKVPLDE------DGQLDLEDILVAIDDKPKLVFLCSpNNPTGN 158
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1225552194 185 DLDELQWRELAALVKRRGLLpFFDMAYQGFGKGVDEDAFAIRHfaaegiP-LFAATSFSKNFSLYGERCG 253
Cdd:TIGR01141 159 LFSRGDIEAVLERTPGDALV-VVDEAYGEFSGEPSTLPLLAEY------PnLIVLRTLSKAFGLAGLRIG 221
|
|
| PRK06225 |
PRK06225 |
pyridoxal phosphate-dependent aminotransferase; |
65-304 |
1.97e-03 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 235749 [Multi-domain] Cd Length: 380 Bit Score: 40.12 E-value: 1.97e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1225552194 65 YLPMEGNAAYRAAVRElTFGgaVPADRVAIaqTLGGSGALKVGADFIARyfPKAGVWVSDPTW---DNHYSIFAGAglpV 141
Cdd:PRK06225 62 YPPPEGFPELRELILK-DLG--LDDDEALI--TAGATESLYLVMRAFLS--PGDNAVTPDPGYliiDNFASRFGAE---V 131
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1225552194 142 QKYRYYDAATGHVDFPGMLaaLEALPAGDVVLLHACCHNPTGADLDELQWRELAALVKRRGLLPFFDMAYQGFGKGvded 221
Cdd:PRK06225 132 IEVPIYSEECNYKLTPELV--KENMDENTRLIYLIDPLNPLGSSYTEEEIKEFAEIARDNDAFLLHDCTYRDFARE---- 205
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1225552194 222 afaiRHFAAEGIPLFAAT--SFSKNFSLYGERCGSLsVVCADareagnVLGQLKATIRRNYssppthGARIIARVLDDAA 299
Cdd:PRK06225 206 ----HTLAAEYAPEHTVTsySFSKIFGMAGLRIGAV-VATPD------LIEVVKSIVINDL------GTNVIAQEAAIAG 268
|
....*..
gi 1225552194 300 L--RAEW 304
Cdd:PRK06225 269 LkvKDEW 275
|
|
| PRK08361 |
PRK08361 |
aspartate aminotransferase; Provisional |
179-346 |
2.86e-03 |
|
aspartate aminotransferase; Provisional
Pssm-ID: 236248 [Multi-domain] Cd Length: 391 Bit Score: 39.48 E-value: 2.86e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1225552194 179 HNPTGADLDELQWRELAALVKRRGLLPFFDMAYQGFgkgVDEDA--FAIRHFAAEGIPLfaATSFSKNFSLYGERCGSLS 256
Cdd:PRK08361 176 NNPTGATLDKEVAKAIADIAEDYNIYILSDEPYEHF---LYEGAkhYPMIKYAPDNTIL--ANSFSKTFAMTGWRLGFVI 250
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1225552194 257 VVCADAREagnvLGQLKATIRRNYSSppthgariIARVLDDAALRAE--WRAeLEGMRTRVADMRAGLYEALRE------ 328
Cdd:PRK08361 251 APEQVIKD----MIKLHAYIIGNVAS--------FVQIAGIEALRSKesWKA-VEEMRKEYNERRKLVLKRLKEmphikv 317
|
170 180
....*....|....*....|.
gi 1225552194 329 RRPDGDFgYL---VKQTGMFS 346
Cdd:PRK08361 318 FEPKGAF-YVfanIDETGMSS 337
|
|
| PRK06108 |
PRK06108 |
pyridoxal phosphate-dependent aminotransferase; |
45-272 |
4.58e-03 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 180404 Cd Length: 382 Bit Score: 38.77 E-value: 4.58e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1225552194 45 AMGAVLRAESALAADLGTrPYLpMEGNAAYRAAVreltFGGAVPADRVAIaqTLGGSGALKVGADFIARyfPKAGVWVSD 124
Cdd:PRK06108 46 AAAALADGETFYTHNLGI-PEL-REALARYVSRL----HGVATPPERIAV--TSSGVQALMLAAQALVG--PGDEVVAVT 115
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1225552194 125 PTWDNHYSIFAGAGL-PVQKYRYYDAATGHVDFPGMLAALEalPAGDVVLLHACcHNPTG--ADLDELQwrELAALVKRR 201
Cdd:PRK06108 116 PLWPNLVAAPKILGArVVCVPLDFGGGGWTLDLDRLLAAIT--PRTRALFINSP-NNPTGwtASRDDLR--AILAHCRRH 190
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1225552194 202 GLLPFFDMAYQGFGKGVDEDAFAIRHFAAEGIPLFAATSFSKNFSLYGERCGSLSVvcadAREAGNVLGQL 272
Cdd:PRK06108 191 GLWIVADEVYERLYYAPGGRAPSFLDIAEPDDRIIFVNSFSKNWAMTGWRLGWLVA----PPALGQVLEKL 257
|
|
| |
