|
Name |
Accession |
Description |
Interval |
E-value |
| CitT |
COG0471 |
Di- and tricarboxylate antiporter [Carbohydrate transport and metabolism]; |
89-470 |
8.49e-73 |
|
Di- and tricarboxylate antiporter [Carbohydrate transport and metabolism];
Pssm-ID: 440239 [Multi-domain] Cd Length: 369 Bit Score: 234.28 E-value: 8.49e-73
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468518747 89 IAGLVISAALSTHKLDKLLGLKVLSLVGVRVHMVVLGMMLATALISMLMSNTAAAALMAPVAVSILSMVGAKSGeSNLGK 168
Cdd:COG0471 1 LGGFVLAAALEKTGLGRRIALLLLKRFGGSPLRLLLGLMLATALLSAFISNTARAAMMLPIALSIAAALGSEKR-SKFGS 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468518747 169 ALMIGIAYAATIGGIGTPVGTPPVPITIGNIESSLGIRISFVKWMIWGVPIVLALTLTAWRVLLLLYPPEREVKTVSREA 248
Cdd:COG0471 80 ALLLPIAFAASIGGMGTLIGTPPNLIAAGLLEEATGIPISFFEWMLVGLPVALVGLLLLWLVLYRLLPPEIKEVPGSKEV 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468518747 249 IERELRSMGPLTLAQKRTIALMALAVILWLIEPLAVLLLSgqqwvldwtyVVSLLVIMLFFMPgiGVLEAKQISE-LDWG 327
Cdd:COG0471 160 IREELAELGPLSRREKIALAIFALTVLLWITGSLHGIPIA----------VVALLGAVLLLLT--GVLTWKDAYKsIPWG 227
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468518747 328 VVFLVAGGLALGEGLRETGILKLIADSLKSPLQAYPPSLVSVIIAAISVLgITVICSITATSATMVPLAISVAKTLGMDP 407
Cdd:COG0471 228 VLLLFGGGLALGAALEKTGLAAWLADALLPLLGGLSPLLLLLLLALLTLL-LTEFASNTATAALLLPIAISLAQALGVNP 306
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2468518747 408 RtsaVVAVAAGLASCYAFLLPANTPPNAITYSYGYFKSYEMAKAGVIVILAGIALIIVIMPLV 470
Cdd:COG0471 307 L---PLALAVAFAASCAFLLPVGTPPNAIVYGSGYYKFKDFLKVGLPLNLIGLVVLLLLGPLW 366
|
|
| dass |
TIGR00785 |
anion transporter; The Divalent Anion:Na+ Symporter (DASS) Family (TC 2.A.47) Functionally ... |
27-466 |
1.36e-60 |
|
anion transporter; The Divalent Anion:Na+ Symporter (DASS) Family (TC 2.A.47) Functionally characterized proteins of the DASS family transport (1) organic di- and tricarboxylates of the Krebs Cycle as well as dicarboxylate amino acid, (2) inorganic sulfate and (3) phosphate. The animal NaDC-1 cotransport 3 Na+ with each dicarboxylate. Protonated tricarboxylates are also cotransported with 3Na+. [Transport and binding proteins, Anions, Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 273267 [Multi-domain] Cd Length: 444 Bit Score: 204.50 E-value: 1.36e-60
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468518747 27 GGLDQRGMAMLGIALLALVYWSTECVPIPVTGLIV----MLLLTLYGIFPFSKSVSFIASKVNILIIAGLVISAALSTHK 102
Cdd:TIGR00785 4 DGLNSGAWLLLAIFVAAIVGWILEPLPLPVTALLAipiiAVLLGVLSAFKFKNALSGFADPTIWLFFGAFILATALVKTG 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468518747 103 LDKLLGLKVLSLVGVR-VHMVVLGMMLATALISMLMSNTAAAALMAPVAV-SILSMVGAK--SGESNLGKALMIGIAYAA 178
Cdd:TIGR00785 84 LGKRIAYKLVGKMGGTtLGLGYFLVFLETLLAPMWPSNTARAGGILLPIIkSLLPLLGSKpeKSPRKIGKYLMLGIAYSA 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468518747 179 TIGGIGTPVGTPPVPITIGNIESSLGIRISFVKWMIWGVPIVLALTLTAWRVLLLLYPPEREVKTVSREAIERELRSMGP 258
Cdd:TIGR00785 164 SIGSSGFLTGSAPNALAAGILSKILGIQISWGDWFLAGLPLGIILLLLVPLLLYVLFPPELKLKDEVDLWAKEELEEMGP 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468518747 259 LTLAQKRTIALMALAVILWLIEPLAVLllsgqqwvldWTYVVSLLVIMLFFMPGIGVLEAKQISELDWGVVFLVAGGLAL 338
Cdd:TIGR00785 244 MSFREKALLGIFLLALLLWIFGGSLGI----------NASVVALLAVVLMLFLGIVTWKDIQKNKVAWNTLILFGGLIGL 313
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468518747 339 GEGLRETGILKLIADSLKSPLQAYPPSLVSVIIAAISVLGITVICSITATSATMVPLAISVAKTLGMDPRtsAVVAVAAG 418
Cdd:TIGR00785 314 AGGLKKSGFIKWFSEKLVGILDGLSPTIAVLVLVVLFYIILYFFASNTAHTAALVPIFFSVASAQGIPLE--LLALALAL 391
|
410 420 430 440
....*....|....*....|....*....|....*....|....*...
gi 2468518747 419 LASCYAFLLPANTPPNAITYSYGYFKSYEMAKAGVIVILAGIALIIVI 466
Cdd:TIGR00785 392 SASLMGFLTPYATPPNAIAYGSGYVKIKDMWRVGAIIGIVGLIVLLLV 439
|
|
| SLC13_permease |
cd01115 |
Permease SLC13 (solute carrier 13). The sodium/dicarboxylate cotransporter NaDC-1 has been ... |
37-470 |
1.12e-48 |
|
Permease SLC13 (solute carrier 13). The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is related to renal and intestinal Na+/sulfate cotransporters and a few putative bacterial permeases. The SLC13-type proteins belong to the ArsB/NhaD superfamily of permeases that translocate sodium and various anions across biological membranes in all three kingdoms of life. A typical ArsB/NhaD permease is composed of 8-13 transmembrane helices.
Pssm-ID: 238535 [Multi-domain] Cd Length: 382 Bit Score: 171.23 E-value: 1.12e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468518747 37 LGIALLALVYWSTECVPIPVTGLIVMLLLTLYGIFPFSKSVSFIASKVNILIIAGLVISAALSTHKLDKLLGLKVLSLVG 116
Cdd:cd01115 1 LAILVFAAVLFVTEALPLDVTALLVPVLLVLLGVVPPKEAFSGFSDPAVILFLAGFILGAALTRTGLAKRIATKLLKRAG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468518747 117 VRVHMVVLGMMLATALISMLMSNTAAAALMAPVAVSILSMVGAKsgesnlGKALMIGIAYAATIGGIGTPVGTPPVPITI 196
Cdd:cd01115 81 KGERRLLLLLMLVTAFLSAFMSNTATVAIMLPVALGLAAKLDIS------PSRLLMPLAFAASIGGMLTLIGTPPNLVAS 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468518747 197 GNIESSLGIRISFVKWMIWGVPIVLALTLTAWrvllllypperevktvsreaierelrsmgpltlaqkrTIALMALAVIL 276
Cdd:cd01115 155 GYLESLGGQGFSFFEFTPIGLPLLIIGLLYLW-------------------------------------FIFRLAVLIIT 197
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468518747 277 WLiepLAVLLLSGQQWVldwtYVVSLLVIMLFFMPGIGVLEAKQI-SELDWGVVFLVAGGLALGEGLRETGILKLIADSL 355
Cdd:cd01115 198 IV---LLAALAAITGLL----PVSVAIAIGAIVLVFGGVLLTKEDyKSIDWGIIFLFAGGIPLGKALESSGAAALIAEAL 270
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468518747 356 KSPLQAYPPSLVSVIIAAISVLgITVICSITATSATMVPLAISVAKTLGMDPRtsaVVAVAAGLASCYAFLLPANTPPNA 435
Cdd:cd01115 271 ISLLGGLPPFAILLLLCLLTLV-LTNFISNTATAVLLAPIALSIALSLGLPPE---ALLLAVAIGASCAFMLPVGTPPNA 346
|
410 420 430
....*....|....*....|....*....|....*
gi 2468518747 436 ITYSYGYFKSYEMAKAGVIVILAGIALIIVIMPLV 470
Cdd:cd01115 347 IVLGPGGYKFSDFAKVGLPLSILSLVVSVTMIPLI 381
|
|
| Na_sulph_symp |
pfam00939 |
Sodium:sulfate symporter transmembrane region; There are also some members in this family that ... |
28-466 |
2.58e-38 |
|
Sodium:sulfate symporter transmembrane region; There are also some members in this family that do not match the Prosite motif, and belong to the subfamily SODIT1.
Pssm-ID: 279307 [Multi-domain] Cd Length: 472 Bit Score: 145.21 E-value: 2.58e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468518747 28 GLDQRGMAMLGIALLALVYWSTECVPIPVTGLIVMLLLTLYGIFPFSKSVSFIAS----KVNILIIAGLVISAALSTHKL 103
Cdd:pfam00939 25 GLPSKAWHLFAIFIATIVGWILEPLPMAVIALFAISLSAILIGTLLAKALSWALSgfssTTTWLVFGAFFISAAFEKTGL 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468518747 104 DKLLGLKVLSLVGVRVhmVVLGMMLATALISMLMSNTAAAALMAPVAVSILSMVGA-------KSGESNLGKALMIGIAY 176
Cdd:pfam00939 105 GRRIALVLVKKMGKRT--LGLGYGLVFSDLLLAPATPSNTARAGGIVFPIIMSLPPafgsdpeKGSERRIGAYLMWTVYQ 182
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468518747 177 AATIGGIGTPVGTPPVPITIGNIESSLGIRISFVKWMIWGVPIVLALTLTAWRVLLLLYPPEREVKTVSREAIERELRSM 256
Cdd:pfam00939 183 STSITSAMFLTAMAPNLLLLGLMNSILGVTITWASWFLAAIPPGVILLLLAPLLLYVLYPPEIKSVPDAKAIAKTELKEL 262
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468518747 257 GPLTLAQKRTIALMALAVILWlieplavlLLSGQQWVLDWTyvVSLLVIMLFFMPGIGVLEAKQISELDWGVVFLVAGGL 336
Cdd:pfam00939 263 GPMTFREKALLGLFVLLLLLW--------IFGGSLNIDATT--VAIIGLALMLLLRILDWKDIVKNKGAWNTLIWLGGLI 332
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468518747 337 ALGEGLRETGILKLIADSLKSPLQAYPPSLVSVIIAAISVLGITVICSITATSATMVPLAISVAKTLGMDPRtsAVVAVA 416
Cdd:pfam00939 333 MLANGLERSGFIEWLGNTLSTSLSGFSPAMAFIIILSLFYLSHYLFASATAHTAAMLPIFAAVAQAIPGAPP--LLAALL 410
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|.
gi 2468518747 417 AGLASCYA-FLLPANTPPNAITYSYGYFKSYEMAKAGVIVILAGIALIIVI 466
Cdd:pfam00939 411 LGFAISLGgFLTPYGTGPGPIYFGSGYLKVKDWWRIGAILTIIGLLILLLL 461
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| CitT |
COG0471 |
Di- and tricarboxylate antiporter [Carbohydrate transport and metabolism]; |
89-470 |
8.49e-73 |
|
Di- and tricarboxylate antiporter [Carbohydrate transport and metabolism];
Pssm-ID: 440239 [Multi-domain] Cd Length: 369 Bit Score: 234.28 E-value: 8.49e-73
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468518747 89 IAGLVISAALSTHKLDKLLGLKVLSLVGVRVHMVVLGMMLATALISMLMSNTAAAALMAPVAVSILSMVGAKSGeSNLGK 168
Cdd:COG0471 1 LGGFVLAAALEKTGLGRRIALLLLKRFGGSPLRLLLGLMLATALLSAFISNTARAAMMLPIALSIAAALGSEKR-SKFGS 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468518747 169 ALMIGIAYAATIGGIGTPVGTPPVPITIGNIESSLGIRISFVKWMIWGVPIVLALTLTAWRVLLLLYPPEREVKTVSREA 248
Cdd:COG0471 80 ALLLPIAFAASIGGMGTLIGTPPNLIAAGLLEEATGIPISFFEWMLVGLPVALVGLLLLWLVLYRLLPPEIKEVPGSKEV 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468518747 249 IERELRSMGPLTLAQKRTIALMALAVILWLIEPLAVLLLSgqqwvldwtyVVSLLVIMLFFMPgiGVLEAKQISE-LDWG 327
Cdd:COG0471 160 IREELAELGPLSRREKIALAIFALTVLLWITGSLHGIPIA----------VVALLGAVLLLLT--GVLTWKDAYKsIPWG 227
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468518747 328 VVFLVAGGLALGEGLRETGILKLIADSLKSPLQAYPPSLVSVIIAAISVLgITVICSITATSATMVPLAISVAKTLGMDP 407
Cdd:COG0471 228 VLLLFGGGLALGAALEKTGLAAWLADALLPLLGGLSPLLLLLLLALLTLL-LTEFASNTATAALLLPIAISLAQALGVNP 306
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2468518747 408 RtsaVVAVAAGLASCYAFLLPANTPPNAITYSYGYFKSYEMAKAGVIVILAGIALIIVIMPLV 470
Cdd:COG0471 307 L---PLALAVAFAASCAFLLPVGTPPNAIVYGSGYYKFKDFLKVGLPLNLIGLVVLLLLGPLW 366
|
|
| dass |
TIGR00785 |
anion transporter; The Divalent Anion:Na+ Symporter (DASS) Family (TC 2.A.47) Functionally ... |
27-466 |
1.36e-60 |
|
anion transporter; The Divalent Anion:Na+ Symporter (DASS) Family (TC 2.A.47) Functionally characterized proteins of the DASS family transport (1) organic di- and tricarboxylates of the Krebs Cycle as well as dicarboxylate amino acid, (2) inorganic sulfate and (3) phosphate. The animal NaDC-1 cotransport 3 Na+ with each dicarboxylate. Protonated tricarboxylates are also cotransported with 3Na+. [Transport and binding proteins, Anions, Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 273267 [Multi-domain] Cd Length: 444 Bit Score: 204.50 E-value: 1.36e-60
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468518747 27 GGLDQRGMAMLGIALLALVYWSTECVPIPVTGLIV----MLLLTLYGIFPFSKSVSFIASKVNILIIAGLVISAALSTHK 102
Cdd:TIGR00785 4 DGLNSGAWLLLAIFVAAIVGWILEPLPLPVTALLAipiiAVLLGVLSAFKFKNALSGFADPTIWLFFGAFILATALVKTG 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468518747 103 LDKLLGLKVLSLVGVR-VHMVVLGMMLATALISMLMSNTAAAALMAPVAV-SILSMVGAK--SGESNLGKALMIGIAYAA 178
Cdd:TIGR00785 84 LGKRIAYKLVGKMGGTtLGLGYFLVFLETLLAPMWPSNTARAGGILLPIIkSLLPLLGSKpeKSPRKIGKYLMLGIAYSA 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468518747 179 TIGGIGTPVGTPPVPITIGNIESSLGIRISFVKWMIWGVPIVLALTLTAWRVLLLLYPPEREVKTVSREAIERELRSMGP 258
Cdd:TIGR00785 164 SIGSSGFLTGSAPNALAAGILSKILGIQISWGDWFLAGLPLGIILLLLVPLLLYVLFPPELKLKDEVDLWAKEELEEMGP 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468518747 259 LTLAQKRTIALMALAVILWLIEPLAVLllsgqqwvldWTYVVSLLVIMLFFMPGIGVLEAKQISELDWGVVFLVAGGLAL 338
Cdd:TIGR00785 244 MSFREKALLGIFLLALLLWIFGGSLGI----------NASVVALLAVVLMLFLGIVTWKDIQKNKVAWNTLILFGGLIGL 313
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468518747 339 GEGLRETGILKLIADSLKSPLQAYPPSLVSVIIAAISVLGITVICSITATSATMVPLAISVAKTLGMDPRtsAVVAVAAG 418
Cdd:TIGR00785 314 AGGLKKSGFIKWFSEKLVGILDGLSPTIAVLVLVVLFYIILYFFASNTAHTAALVPIFFSVASAQGIPLE--LLALALAL 391
|
410 420 430 440
....*....|....*....|....*....|....*....|....*...
gi 2468518747 419 LASCYAFLLPANTPPNAITYSYGYFKSYEMAKAGVIVILAGIALIIVI 466
Cdd:TIGR00785 392 SASLMGFLTPYATPPNAIAYGSGYVKIKDMWRVGAIIGIVGLIVLLLV 439
|
|
| SLC13_permease |
cd01115 |
Permease SLC13 (solute carrier 13). The sodium/dicarboxylate cotransporter NaDC-1 has been ... |
37-470 |
1.12e-48 |
|
Permease SLC13 (solute carrier 13). The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is related to renal and intestinal Na+/sulfate cotransporters and a few putative bacterial permeases. The SLC13-type proteins belong to the ArsB/NhaD superfamily of permeases that translocate sodium and various anions across biological membranes in all three kingdoms of life. A typical ArsB/NhaD permease is composed of 8-13 transmembrane helices.
Pssm-ID: 238535 [Multi-domain] Cd Length: 382 Bit Score: 171.23 E-value: 1.12e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468518747 37 LGIALLALVYWSTECVPIPVTGLIVMLLLTLYGIFPFSKSVSFIASKVNILIIAGLVISAALSTHKLDKLLGLKVLSLVG 116
Cdd:cd01115 1 LAILVFAAVLFVTEALPLDVTALLVPVLLVLLGVVPPKEAFSGFSDPAVILFLAGFILGAALTRTGLAKRIATKLLKRAG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468518747 117 VRVHMVVLGMMLATALISMLMSNTAAAALMAPVAVSILSMVGAKsgesnlGKALMIGIAYAATIGGIGTPVGTPPVPITI 196
Cdd:cd01115 81 KGERRLLLLLMLVTAFLSAFMSNTATVAIMLPVALGLAAKLDIS------PSRLLMPLAFAASIGGMLTLIGTPPNLVAS 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468518747 197 GNIESSLGIRISFVKWMIWGVPIVLALTLTAWrvllllypperevktvsreaierelrsmgpltlaqkrTIALMALAVIL 276
Cdd:cd01115 155 GYLESLGGQGFSFFEFTPIGLPLLIIGLLYLW-------------------------------------FIFRLAVLIIT 197
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468518747 277 WLiepLAVLLLSGQQWVldwtYVVSLLVIMLFFMPGIGVLEAKQI-SELDWGVVFLVAGGLALGEGLRETGILKLIADSL 355
Cdd:cd01115 198 IV---LLAALAAITGLL----PVSVAIAIGAIVLVFGGVLLTKEDyKSIDWGIIFLFAGGIPLGKALESSGAAALIAEAL 270
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468518747 356 KSPLQAYPPSLVSVIIAAISVLgITVICSITATSATMVPLAISVAKTLGMDPRtsaVVAVAAGLASCYAFLLPANTPPNA 435
Cdd:cd01115 271 ISLLGGLPPFAILLLLCLLTLV-LTNFISNTATAVLLAPIALSIALSLGLPPE---ALLLAVAIGASCAFMLPVGTPPNA 346
|
410 420 430
....*....|....*....|....*....|....*
gi 2468518747 436 ITYSYGYFKSYEMAKAGVIVILAGIALIIVIMPLV 470
Cdd:cd01115 347 IVLGPGGYKFSDFAKVGLPLSILSLVVSVTMIPLI 381
|
|
| Na_sulph_symp |
pfam00939 |
Sodium:sulfate symporter transmembrane region; There are also some members in this family that ... |
28-466 |
2.58e-38 |
|
Sodium:sulfate symporter transmembrane region; There are also some members in this family that do not match the Prosite motif, and belong to the subfamily SODIT1.
Pssm-ID: 279307 [Multi-domain] Cd Length: 472 Bit Score: 145.21 E-value: 2.58e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468518747 28 GLDQRGMAMLGIALLALVYWSTECVPIPVTGLIVMLLLTLYGIFPFSKSVSFIAS----KVNILIIAGLVISAALSTHKL 103
Cdd:pfam00939 25 GLPSKAWHLFAIFIATIVGWILEPLPMAVIALFAISLSAILIGTLLAKALSWALSgfssTTTWLVFGAFFISAAFEKTGL 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468518747 104 DKLLGLKVLSLVGVRVhmVVLGMMLATALISMLMSNTAAAALMAPVAVSILSMVGA-------KSGESNLGKALMIGIAY 176
Cdd:pfam00939 105 GRRIALVLVKKMGKRT--LGLGYGLVFSDLLLAPATPSNTARAGGIVFPIIMSLPPafgsdpeKGSERRIGAYLMWTVYQ 182
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468518747 177 AATIGGIGTPVGTPPVPITIGNIESSLGIRISFVKWMIWGVPIVLALTLTAWRVLLLLYPPEREVKTVSREAIERELRSM 256
Cdd:pfam00939 183 STSITSAMFLTAMAPNLLLLGLMNSILGVTITWASWFLAAIPPGVILLLLAPLLLYVLYPPEIKSVPDAKAIAKTELKEL 262
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468518747 257 GPLTLAQKRTIALMALAVILWlieplavlLLSGQQWVLDWTyvVSLLVIMLFFMPGIGVLEAKQISELDWGVVFLVAGGL 336
Cdd:pfam00939 263 GPMTFREKALLGLFVLLLLLW--------IFGGSLNIDATT--VAIIGLALMLLLRILDWKDIVKNKGAWNTLIWLGGLI 332
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468518747 337 ALGEGLRETGILKLIADSLKSPLQAYPPSLVSVIIAAISVLGITVICSITATSATMVPLAISVAKTLGMDPRtsAVVAVA 416
Cdd:pfam00939 333 MLANGLERSGFIEWLGNTLSTSLSGFSPAMAFIIILSLFYLSHYLFASATAHTAAMLPIFAAVAQAIPGAPP--LLAALL 410
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|.
gi 2468518747 417 AGLASCYA-FLLPANTPPNAITYSYGYFKSYEMAKAGVIVILAGIALIIVI 466
Cdd:pfam00939 411 LGFAISLGgFLTPYGTGPGPIYFGSGYLKVKDWWRIGAILTIIGLLILLLL 461
|
|
| ArsB_NhaD_permease |
cd00625 |
Anion permease ArsB/NhaD. These permeases have been shown to translocate sodium, arsenate, ... |
44-467 |
5.30e-23 |
|
Anion permease ArsB/NhaD. These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life. A typical anion permease contains 8-13 transmembrane helices and can function either independently as a chemiosmotic transporter or as a channel-forming subunit of an ATP-driven anion pump.
Pssm-ID: 238344 [Multi-domain] Cd Length: 396 Bit Score: 100.40 E-value: 5.30e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468518747 44 LVYWSTECVPIPVTGLIVMLLLTLYGIFPFSKSVSFIASKVNILIIAGLVISAALSTHKLDKLLGLKvLSLVGVRVHMVV 123
Cdd:cd00625 1 YVLIRPEKLPRAVVALLGAVLLVLLGVVSPKEALSAIDWETILLLFGMMILSAALEETGLFDRLAAK-LARASKGSRRLL 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468518747 124 LGMMLATALISMLMSNTAAAALMAPVAVSILSMVGAKSgesnlGKALMIGIAYAATIGGIGTPVGTPPvpitigNIESSL 203
Cdd:cd00625 80 LLLMLLTAALSAFFSNDATAVLLTPIVLALLRKLGLSP-----PVPLLLALAFAANIGGAATPIGNPP------NLIIAS 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468518747 204 GIRISFVKWMIWGVPIVLALTLTAWRVLLLLYPPEREVK-TVSREAIERELRSMGPLTLAQKRTIALMALAVILWLIEPl 282
Cdd:cd00625 149 LSGLGFLDFLAFMAPPALGLLLLLLGLLYLLFRKKLLLPdEDKLTVLAEPLPARPLLKKFLLLALLLLLLFVLLFFFLI- 227
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468518747 283 avlllsgqqwvlDWTYVVSLLVIMLFFMPGIGVLEAKQISELDWGVVFLVAGGLALGEGLRETGILKLIADSLKSPLQAy 362
Cdd:cd00625 228 ------------PLGLIALLGALLLLLLLVRGLDPEEVLKSVDWGTLLFFAGLFVLVGALESTGLLEWLAELLVALVGL- 294
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468518747 363 pPSLVSVIIAAISVLGITVICSITATSATMVPLAISVAKT-----LGMDPRTSAVVAVAAGLAscyAFLLPANTPPNAIT 437
Cdd:cd00625 295 -PPLAALLLIGLLSALLSNFISNVPTVALLLPIAASLAPPepawlALALGSTLGGNLTLIGSL---ANLIPLGAAENAGV 370
|
410 420 430
....*....|....*....|....*....|
gi 2468518747 438 ysygYFKSYEMAKAGVIVILAGIALIIVIM 467
Cdd:cd00625 371 ----GISFGEFLKVGLPLTLLSLVVSLLYL 396
|
|
| CitMHS |
pfam03600 |
Citrate transporter; |
44-407 |
5.80e-22 |
|
Citrate transporter;
Pssm-ID: 460985 [Multi-domain] Cd Length: 342 Bit Score: 96.61 E-value: 5.80e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468518747 44 LVYWSTECVPIPVTGLIVMLLLTLYGIFPFSKSVSFIASKVNILIIAGLVISAALSTHKLDKLLGLKVLSLVGVRVHMVV 123
Cdd:pfam03600 1 YVLIITEKLPRDVVALLGAVLLVLLGVLTPEEALSGIDSPTILLLLGMMIIGAILERTGLFDRLALKLLRLAGGKPRRLL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468518747 124 LGMMLATALISMLMSNTAAAALMAPVAVSIlsmvgAKSGESNLgKALMIGIAYAATIGGIGTPVGTPPVpITIGNIESSL 203
Cdd:pfam03600 81 VALMLATALLSAFLSNDGTVLIMIPIVLAL-----ARRLGLPP-SPLLIALAFAANIGGTATPIGDPPN-IIIASALGLS 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468518747 204 GIRISFVKWMIWGVPIVLALTLTAWRVLLLLYPPEREVKTVSREAIERelrsmgpltlAQKRTIALMALAVILWLiepla 283
Cdd:pfam03600 154 FGDFGFFMFPPVGVALLLVGLLPLLLIFRKLLPVRKEEEAELEELRKR----------AIKDKLLLAISALVLAL----- 218
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468518747 284 vlllsgqqWVLDWTYVVSLLVIMLFFMPGIGVLEAKQISE-LDWGVVFLVAGGLALGEGLRETGILKLIADSlkspLQAY 362
Cdd:pfam03600 219 --------VILGFLLLSVLALAGALLLLLTGVLDPEEALKaVDWSTLLFFAGLFILVGALEKTGLADALADA----LGGL 286
|
330 340 350 360
....*....|....*....|....*....|....*....|....*
gi 2468518747 363 PPSLVSVIIAAISVLGITVICSITATSATMVPLAISVAKTLGMDP 407
Cdd:pfam03600 287 SGLLVALALILWLSALLSAFISNVPTAALMAPIIVGMAPAAGLGD 331
|
|
| ArsB |
COG1055 |
Na+/H+ antiporter NhaD or related arsenite permease [Inorganic ion transport and metabolism]; |
34-407 |
1.86e-12 |
|
Na+/H+ antiporter NhaD or related arsenite permease [Inorganic ion transport and metabolism];
Pssm-ID: 440675 [Multi-domain] Cd Length: 415 Bit Score: 68.62 E-value: 1.86e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468518747 34 MAMLGIALLALVY----WSTECVPIPVTGLIVMLLLTLYGIFPFSKSVSFIASKVNILIIAGLVISAALSTHKLDKLLGL 109
Cdd:COG1055 1 MMILALAIFVLTYlliiLEPRGLNRAVAALLGAALLLLLGVVSLEDALEAIDWNTILFLLGMMIIVAILDESGFFEWLAI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468518747 110 KVLSLVGVRVHMVVLGMMLATALISMLMSNTAAAALMAPVAVSILSMVGAKSgesnlgKALMIGIAYAATIGGIGTPVGT 189
Cdd:COG1055 81 KLARRAKGSPRRLLWLLGLLTALLSAFLDNDTTALLLTPVVLAIARRLGLNP------VPFLIAIVFAANIGGAATPIGN 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468518747 190 PPvpitigNIESSLGIRISFVKWMIWGVPIVLALTLTAWRVLLLLYPPEREVKTVSREAIERELRSMGPLtlaqkrTIAL 269
Cdd:COG1055 155 PT------NIMIASAGGLSFLDFLANLFPPSLVSLLVTLLVLYLLFRKELPAAPDLEDDPKEAIKDRRLL------RISL 222
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468518747 270 MALAVILwliepLAVLLLSGQQWVLDWTYVVSLLVIMLFFmpGIGVLEAkqISELDWGVVFLVAGGLALGEGLRETGILK 349
Cdd:COG1055 223 LVLALLL-----VGFVLHSFLGLPPALIALLGAAVLLLLA--RVDVREV--LKKVDWSTLLFFIGLFVVVGGLENTGLLD 293
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*...
gi 2468518747 350 LIADSLkSPLQAYPPSLVSVIIAAISVLGITVICSITATsATMVPLAISVAKTLGMDP 407
Cdd:COG1055 294 LLAELL-ASLTGGNLLLAALLILWLSAILSAVVDNVPLV-AALLPLIPDLGATGNPEP 349
|
|
| CitT |
COG0471 |
Di- and tricarboxylate antiporter [Carbohydrate transport and metabolism]; |
25-236 |
3.16e-07 |
|
Di- and tricarboxylate antiporter [Carbohydrate transport and metabolism];
Pssm-ID: 440239 [Multi-domain] Cd Length: 369 Bit Score: 52.46 E-value: 3.16e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468518747 25 PIGGLDQRGMAMLGIALLALVYWSTE---CVPIPVTGLIVMLLLTLYGIFPFSKSVSFIASKVNILIIAGLVISAALSTH 101
Cdd:COG0471 166 ELGPLSRREKIALAIFALTVLLWITGslhGIPIAVVALLGAVLLLLTGVLTWKDAYKSIPWGVLLLFGGGLALGAALEKT 245
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468518747 102 KLDKLLGLKVLSLV-GVRVHMVVLGMMLATALISMLMSNTAAAALMAPVAVSILSMVGAKSgesnlgKALMIGIAYAATI 180
Cdd:COG0471 246 GLAAWLADALLPLLgGLSPLLLLLLLALLTLLLTEFASNTATAALLLPIAISLAQALGVNP------LPLALAVAFAASC 319
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 2468518747 181 GGIgTPVGTPPVPITIGniessLGiRISFVKWMIWGVPIVLALTLTAWRVLLLLYP 236
Cdd:COG0471 320 AFL-LPVGTPPNAIVYG-----SG-YYKFKDFLKVGLPLNLIGLVVLLLLGPLWWP 368
|
|
| P_permease |
cd01116 |
Permease P (pink-eyed dilution). Mutations in the human melanosomal P gene were responsible ... |
58-407 |
5.32e-06 |
|
Permease P (pink-eyed dilution). Mutations in the human melanosomal P gene were responsible for classic phenotype of oculocutaneous albinism type 2 (OCA2). Although the precise function of the P protein is unknown, it was predicted to regulate the intraorganelle pH, together with the ATP-driven proton pump. It shows significant sequence similarity to the Na+/H+ antiporter NhaD from Vibrio parahaemolyticus. Both proteins belong to ArsB/NhaD superfamily of permeases that translocate sodium, arsenate, sulfate, and organic anions across biological membranes in all three kingdoms of life. A typical ArsB/NhaD permease contains 8-13 transmembrane domains.
Pssm-ID: 238536 [Multi-domain] Cd Length: 413 Bit Score: 48.40 E-value: 5.32e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468518747 58 GLIVMLLLTLY-GIFPFSKSVSFIASKVNILIIAGLVISAALSTHKLDKLLGLKVLSLVGVRVHMVVLGMMLATALISML 136
Cdd:cd01116 22 GALWLVILGLAtLSPDLETIVSWVDWETLALLLGMMIIVSILSETGVFEYLAIWAVKISKGRPWRLLLLLGLLTAFLSAF 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468518747 137 MSNTAAAALMAPVAVSILSMVGAKSgesnlgKALMIGIAYAATIGGIGTPVGTPPvPITIGNIesslgIRISFVKWMIWG 216
Cdd:cd01116 102 LDNVTTVLLMVPVTIRLCEVLGLNP------VPVLISEVIAANIGGAATLIGDPP-NIMIGSA-----AGLTFNDFLLHM 169
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468518747 217 VPIVLaLTLTAWRVLLLLYPPEREVKTVSREAIERELRSMGPLtlaqKRTIALMALAVILWLIeplAVLLLSGQQWVLDW 296
Cdd:cd01116 170 LPSVV-LALVVTFILLYFLYRNILKAREEDVLALAELEPKYPI----KDKVLLLKSLTILTLV---IIGFVLHSPLGVSL 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468518747 297 TYVVSLLVIMLFFMPGIGVLEaKQISELDWGVVFLVAGGLALGEGLRETGILKLIADSLKSpLQAYPPSLVSVIIAAISV 376
Cdd:cd01116 242 GWIALLGALLLLLLADKLDFE-DVLSRVEWDTLLFFAGLFVLVGGLEELGIIEWIAELLVG-VILGRIAVAVILILWISA 319
|
330 340 350
....*....|....*....|....*....|.
gi 2468518747 377 LGITVICSITATsATMVPLAISVAKTLGMDP 407
Cdd:cd01116 320 LLSAFIDNIPVT-ATMIPIVKDLASQLGIPL 349
|
|
| SLC13_permease |
cd01115 |
Permease SLC13 (solute carrier 13). The sodium/dicarboxylate cotransporter NaDC-1 has been ... |
282-474 |
1.11e-04 |
|
Permease SLC13 (solute carrier 13). The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is related to renal and intestinal Na+/sulfate cotransporters and a few putative bacterial permeases. The SLC13-type proteins belong to the ArsB/NhaD superfamily of permeases that translocate sodium and various anions across biological membranes in all three kingdoms of life. A typical ArsB/NhaD permease is composed of 8-13 transmembrane helices.
Pssm-ID: 238535 [Multi-domain] Cd Length: 382 Bit Score: 44.50 E-value: 1.11e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468518747 282 LAVLLLSGQQWVLDW--TYVVSLLVIMLFFMpgIGVLEAKQISELDWG-VVFLVAGGLALGEGLRETGILKLIADSLKSP 358
Cdd:cd01115 1 LAILVFAAVLFVTEAlpLDVTALLVPVLLVL--LGVVPPKEAFSGFSDpAVILFLAGFILGAALTRTGLAKRIATKLLKR 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468518747 359 LQAYPPSLVSVIIAAISVLGITVicSITATSATMVPLAISVAKTLGMDPrtSAVVAVAAGLASCYAFLLPANTPPNAI-- 436
Cdd:cd01115 79 AGKGERRLLLLLMLVTAFLSAFM--SNTATVAIMLPVALGLAAKLDISP--SRLLMPLAFAASIGGMLTLIGTPPNLVas 154
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 2468518747 437 ----TYSYGYFKSYEMAKAGVIVILAGIALIIVIMPLVSLLI 474
Cdd:cd01115 155 gyleSLGGQGFSFFEFTPIGLPLLIIGLLYLWFIFRLAVLII 196
|
|
| dass |
TIGR00785 |
anion transporter; The Divalent Anion:Na+ Symporter (DASS) Family (TC 2.A.47) Functionally ... |
24-228 |
1.46e-04 |
|
anion transporter; The Divalent Anion:Na+ Symporter (DASS) Family (TC 2.A.47) Functionally characterized proteins of the DASS family transport (1) organic di- and tricarboxylates of the Krebs Cycle as well as dicarboxylate amino acid, (2) inorganic sulfate and (3) phosphate. The animal NaDC-1 cotransport 3 Na+ with each dicarboxylate. Protonated tricarboxylates are also cotransported with 3Na+. [Transport and binding proteins, Anions, Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 273267 [Multi-domain] Cd Length: 444 Bit Score: 44.26 E-value: 1.46e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468518747 24 SPIGGLDQRGMAMLGIALLALVYWSTEC---VPIPVTGLIVMLLLTLYGIFPFSKSVS-FIASKVNILIIAGLVISAALS 99
Cdd:TIGR00785 239 EEMGPMSFREKALLGIFLLALLLWIFGGslgINASVVALLAVVLMLFLGIVTWKDIQKnKVAWNTLILFGGLIGLAGGLK 318
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468518747 100 THKLDKLLGLKVLSLVGVRVHMVVLG--MMLATALISMLMSNTAAAALMAPVAVSILSMVGAKSgesnlgKALMIGIAYA 177
Cdd:TIGR00785 319 KSGFIKWFSEKLVGILDGLSPTIAVLvlVVLFYIILYFFASNTAHTAALVPIFFSVASAQGIPL------ELLALALALS 392
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 2468518747 178 ATIGGIGTPVGTPPVPITIGniesSLGIRISfvKWMIWGVP------IVLALTLTAW 228
Cdd:TIGR00785 393 ASLMGFLTPYATPPNAIAYG----SGYVKIK--DMWRVGAIigivglIVLLLVGTLW 443
|
|
| ArsB |
COG1055 |
Na+/H+ antiporter NhaD or related arsenite permease [Inorganic ion transport and metabolism]; |
34-235 |
4.81e-04 |
|
Na+/H+ antiporter NhaD or related arsenite permease [Inorganic ion transport and metabolism];
Pssm-ID: 440675 [Multi-domain] Cd Length: 415 Bit Score: 42.42 E-value: 4.81e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468518747 34 MAMLGIALLALVYWSTECVPIPV-----TGLIVMLLLTLYGIFPFSKSVSFIAskvnILIIAGL-VISAALSTHKLDKLL 107
Cdd:COG1055 220 ISLLVLALLLVGFVLHSFLGLPPalialLGAAVLLLLARVDVREVLKKVDWST----LLFFIGLfVVVGGLENTGLLDLL 295
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468518747 108 GLKVLSLVGVRVHMVVLGMMLATALISMLMSNtaaaalmaPVAVSILSMVGAKSGESNLGKALMIGIAYAATIGGIGTPV 187
Cdd:COG1055 296 AELLASLTGGNLLLAALLILWLSAILSAVVDN--------VPLVAALLPLIPDLGATGNPEPLWLALALGATLGGNLTPI 367
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 2468518747 188 GTPPVPITIGNIESSlGIRISFVKWMIWGVPIVLALTLTAWRVLLLLY 235
Cdd:COG1055 368 GSAANVIVLGIAEKK-GIKISFGEFLKVGLPLTLLTLLIALLYLLLLY 414
|
|
| |
