NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|564387696|ref|XP_006252586|]
View 

protein O-mannosyl-transferase TMTC4 isoform X2 [Rattus norvegicus]

Protein Classification

DUF1736 and TPR domain-containing protein( domain architecture ID 12091460)

DUF1736 and TPR domain-containing protein

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
506-712 1.49e-39

Tetratricopeptide (TPR) repeat [General function prediction only];


:

Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 146.31  E-value: 1.49e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564387696 506 LSVCPLNAKVHYNIGKNLADQGNQTAAIKYYREAVRLNPKYVHAMNNLGNILKERNELQEAEELLSLAVQIQPDFAAAWM 585
Cdd:COG0457    1 LELDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALN 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564387696 586 NLGIVQNSLKRFEEAEQSYRTAIKHRRKYPDCYYNLGRLYADLNRHVDALNAWRNATVMKPEHSLAWNNMVILLDNTGNL 665
Cdd:COG0457   81 NLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRY 160

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*..
gi 564387696 666 AQAEAVGREALQLIPNDHSLMFSLANVLGKSQKYKESEALFLKAIKA 712
Cdd:COG0457  161 EEALELLEKLEAAALAALLAAALGEAALALAAAEVLLALLLALEQAL 207
TMTC_DUF1736 pfam08409
Protein O-mannosyl-transferase TMTC, DUF1736; This domain of unknown function is found in ...
 323-397 1.18e-38

Protein O-mannosyl-transferase TMTC, DUF1736; This domain of unknown function is found in O-mannosyl -transferases TMTC1-4, and constitutes a loop between TM7 and TM8 located in the ER lumen that contains a small hydrophobic, but not membrane-embedded helix. This loop is critical for catalysis and binding of ligands, especially the lipid-linked sugar moiety. TMTCs transfers mannosyl residues to the hydroxyl group of serine or threonine residues. The 4 members of the TMTC family are O-mannosyl-transferases acting primarily on the cadherin superfamily; each member has distinct roles in decorating the cadherin domains with O-linked mannose glycans at specific regions. These proteins also act as O-mannosyl-transferase on other proteins such as PDIA3.


:

Pssm-ID: 462468  Cd Length: 75  Bit Score: 137.66  E-value: 1.18e-38
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 564387696  323 GTGPPAFTEVDNPASFADSVLVRAINYNYYYSLNAWLLLCPWWLCFDWSMGCIPLIKSVGDWRVIALAALWLCLI 397
Cdd:pfam08409   1 GGQLPVFSASDNPAAFSPSLLTRTLTYNYLPALNAWLLLFPSWLCFDWSMGSIPLIESLSDPRNLATLAFYGALA 75
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
676-769 1.27e-10

Tetratricopeptide (TPR) repeat [General function prediction only];


:

Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 62.33  E-value: 1.27e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564387696 676 LQLIPNDHSLMFSLANVLGKSQKYKESEALFLKAIKANPNVASYHGNLAVLYHRWGHLDSAKKHYEISLQLDPVAVGTKE 755
Cdd:COG0457    1 LELDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALN 80

                         90
                 ....*....|....
gi 564387696 756 NYSLLRRKLEQMQK 769
Cdd:COG0457   81 NLGLALQALGRYEE 94
 
Name Accession Description Interval E-value
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
506-712 1.49e-39

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 146.31  E-value: 1.49e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564387696 506 LSVCPLNAKVHYNIGKNLADQGNQTAAIKYYREAVRLNPKYVHAMNNLGNILKERNELQEAEELLSLAVQIQPDFAAAWM 585
Cdd:COG0457    1 LELDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALN 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564387696 586 NLGIVQNSLKRFEEAEQSYRTAIKHRRKYPDCYYNLGRLYADLNRHVDALNAWRNATVMKPEHSLAWNNMVILLDNTGNL 665
Cdd:COG0457   81 NLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRY 160

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*..
gi 564387696 666 AQAEAVGREALQLIPNDHSLMFSLANVLGKSQKYKESEALFLKAIKA 712
Cdd:COG0457  161 EEALELLEKLEAAALAALLAAALGEAALALAAAEVLLALLLALEQAL 207
TMTC_DUF1736 pfam08409
Protein O-mannosyl-transferase TMTC, DUF1736; This domain of unknown function is found in ...
 323-397 1.18e-38

Protein O-mannosyl-transferase TMTC, DUF1736; This domain of unknown function is found in O-mannosyl -transferases TMTC1-4, and constitutes a loop between TM7 and TM8 located in the ER lumen that contains a small hydrophobic, but not membrane-embedded helix. This loop is critical for catalysis and binding of ligands, especially the lipid-linked sugar moiety. TMTCs transfers mannosyl residues to the hydroxyl group of serine or threonine residues. The 4 members of the TMTC family are O-mannosyl-transferases acting primarily on the cadherin superfamily; each member has distinct roles in decorating the cadherin domains with O-linked mannose glycans at specific regions. These proteins also act as O-mannosyl-transferase on other proteins such as PDIA3.


Pssm-ID: 462468  Cd Length: 75  Bit Score: 137.66  E-value: 1.18e-38
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 564387696  323 GTGPPAFTEVDNPASFADSVLVRAINYNYYYSLNAWLLLCPWWLCFDWSMGCIPLIKSVGDWRVIALAALWLCLI 397
Cdd:pfam08409   1 GGQLPVFSASDNPAAFSPSLLTRTLTYNYLPALNAWLLLFPSWLCFDWSMGSIPLIESLSDPRNLATLAFYGALA 75
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 501-748 1.53e-16

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 84.36  E-value: 1.53e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564387696  501 LFRSALSVCPLNAKVHYNIGKNLADQGNQTAAIKYYREAVRLNPKYVHAMNNLGNILKERNELQEAEELLSLAVQIQPDF 580
Cdd:TIGR02917 589 ILNEAADAAPDSPEAWLMLGRAQLAAGDLNKAVSSFKKLLALQPDSALALLLLADAYAVMKNYAKAITSLKRALELKPDN 668

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564387696  581 AAAWMNLGIVQNSLKRFEEAEQSYRTAIKHRRKYPDCYYNLGRLYADLNRHVDALNAWRNATVMKPEHSLAWNNMVILLD 660
Cdd:TIGR02917 669 TEAQIGLAQLLLAAKRTESAKKIAKSLQKQHPKAALGFELEGDLYLRQKDYPAAIQAYRKALKRAPSSQNAIKLHRALLA 748

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564387696  661 NtGNLAQAEAVGREALQLIPNDHSLMFSLANVLGKSQKYKESEALFLKAIKANPNVASYHGNLAVLYHRwghLDSAK--K 738
Cdd:TIGR02917 749 S-GNTAEAVKTLEAWLKTHPNDAVLRTALAELYLAQKDYDKAIKHYQTVVKKAPDNAVVLNNLAWLYLE---LKDPRalE 824

                         250
                  ....*....|
gi 564387696  739 HYEISLQLDP 748
Cdd:TIGR02917 825 YAERALKLAP 834
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
676-769 1.27e-10

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 62.33  E-value: 1.27e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564387696 676 LQLIPNDHSLMFSLANVLGKSQKYKESEALFLKAIKANPNVASYHGNLAVLYHRWGHLDSAKKHYEISLQLDPVAVGTKE 755
Cdd:COG0457    1 LELDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALN 80

                         90
                 ....*....|....
gi 564387696 756 NYSLLRRKLEQMQK 769
Cdd:COG0457   81 NLGLALQALGRYEE 94
C39_PA2778_fam NF033920
PA2778 family cysteine peptidase; Members of this family are MEROPS classification C39 family ...
 523-609 4.31e-09

PA2778 family cysteine peptidase; Members of this family are MEROPS classification C39 family cysteine peptidases, a group that includes many processing enzyme for peptide natural products such as lantibiotics and other bacteriocins. This family, more specifically, includes PA2778 as found in Pseudomonas aeruginosa. All members of the defining seed alignment are encoded in the vicinity of a homolog of PA2779 (see HMM NF033919). Note that the C-terminal region consists largely of tetratricopeptide repeats (TPR), so classification using this HMM must be based on comparing the top domain score to the second gathering threshold (GA2).


Pssm-ID: 468245 [Multi-domain]  Cd Length: 255  Bit Score: 57.95  E-value: 4.31e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564387696 523 LADQGNQTAAIKYYREAVRLNPKYVHAMNNLGNILKERNELQEAEELLSLAVQIQPDFAAAWMNLGIVQNSLKRFEEAEQ 602
Cdd:NF033920 166 LEQTGQPEAALAAYQTATKRWPDSWLAYFGLGNAAYAAGDYAAAAAAFRQAVERHPDSAAAWNNLAYALAAQGCTAQARA 245


                 ....*..
gi 564387696 603 SYRTAIK 609
Cdd:NF033920 246 AAECALA 252
PRK11447 PRK11447
cellulose synthase subunit BcsC; Provisional
 503-717 3.32e-08

cellulose synthase subunit BcsC; Provisional


Pssm-ID: 183140 [Multi-domain]  Cd Length: 1157  Bit Score: 57.40  E-value: 3.32e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564387696  503 RSALSVCPLNAKVHYNIGKNLADQGNQTAAIKYYREAVRLNP---------------KYVHAMNNLGNILKErNELQEAE 567
Cdd:PRK11447  293 QQAVRANPKDSEALGALGQAYSQQGDRARAVAQFEKALALDPhssnrdkwesllkvnRYWLLIQQGDAALKA-NNLAQAE 371

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564387696  568 ELLSLAVQIQPDFAAAWMNLGIVQNSLKRFEEAEQSYRTAikhRRKYPDcyyN------LGRLY-------ADlnRHVDA 634
Cdd:PRK11447  372 RLYQQARQVDNTDSYAVLGLGDVAMARKDYAAAERYYQQA---LRMDPG---NtnavrgLANLYrqqspekAL--AFIAS 443

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564387696  635 LNAWRNATVMKPEHSLAwNNMVIL----LDNTGNLAQAEAVGREALQLIPNDHSLMFSLANVLGKSQKYKESEALFLKAI 710
Cdd:PRK11447  444 LSASQRRSIDDIERSLQ-NDRLAQqaeaLENQGKWAQAAELQRQRLALDPGSVWLTYRLAQDLRQAGQRSQADALMRRLA 522


                  ....*..
gi 564387696  711 KANPNVA 717
Cdd:PRK11447  523 QQKPNDP 529
ACL4-like cd24142
Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 ...
 522-608 7.25e-08

Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 (ACL4) acts as a chaperone for the L4 ribosomal subunit, encoded by RPL4A and RPL4B, and is required for hierarchical ribosome assembly. It is required for the soluble expression of newly synthesized RPL4 and for the protection of RPL4 from the Tom1-dependent cellular degradation machinery. ACL4 shields ribosomal protein L4 until timely release and insertion into the pre-ribosome is possible, once ribosomal protein L18 is present.


Pssm-ID: 467942 [Multi-domain]  Cd Length: 306  Bit Score: 54.94  E-value: 7.25e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564387696 522 NLADQGNQTAAIKYYREAVRLNPKYVHAMNNLGNILKERNELQEAEELLSLAVQIQPD-FAAAWMNLG-IVQNslkrfEE 599
Cdd:cd24142    9 ELLDQGNFELALKFLQRALELEPNNVEALELLGEILLELGDVEEAREVLLRAIELDPDgGYEKYLYLGqLSGG-----EE 83


                 ....*....
gi 564387696 600 AEQSYRTAI 608
Cdd:cd24142   84 ALQYYEKGI 92
TPR_19 pfam14559
Tetratricopeptide repeat;
526-585 5.70e-07

Tetratricopeptide repeat;


Pssm-ID: 434038 [Multi-domain]  Cd Length: 65  Bit Score: 47.19  E-value: 5.70e-07
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 564387696  526 QGNQTAAIKYYREAVRLNPKYVHAMNNLGNILKERNELQEAEELLSLAVQIQPDFAAAWM 585
Cdd:pfam14559   1 EGDYAEALELLEQALAEDPDNAEARLGLAEALLALGRLDEAEALLAALPAADPDDPRYAA 60
C39_PA2778_fam NF033920
PA2778 family cysteine peptidase; Members of this family are MEROPS classification C39 family ...
 659-748 1.96e-05

PA2778 family cysteine peptidase; Members of this family are MEROPS classification C39 family cysteine peptidases, a group that includes many processing enzyme for peptide natural products such as lantibiotics and other bacteriocins. This family, more specifically, includes PA2778 as found in Pseudomonas aeruginosa. All members of the defining seed alignment are encoded in the vicinity of a homolog of PA2779 (see HMM NF033919). Note that the C-terminal region consists largely of tetratricopeptide repeats (TPR), so classification using this HMM must be based on comparing the top domain score to the second gathering threshold (GA2).


Pssm-ID: 468245 [Multi-domain]  Cd Length: 255  Bit Score: 46.77  E-value: 1.96e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564387696 659 LDNTGNLAQAEAVGREALQLIPNDHSLMFSLANVLGKSQKYKESEALFLKAIKANPNVASYHGNLAVLYHRWGHLDSAKK 738
Cdd:NF033920 166 LEQTGQPEAALAAYQTATKRWPDSWLAYFGLGNAAYAAGDYAAAAAAFRQAVERHPDSAAAWNNLAYALAAQGCTAQARA 245

                         90
                 ....*....|
gi 564387696 739 HYEISLQLDP 748
Cdd:NF033920 246 AAECALALAP 255
TPR_12 pfam13424
Tetratricopeptide repeat;
689-746 9.42e-05

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 41.22  E-value: 9.42e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 564387696  689 LANVLGKSQKYKESEALFLKAIKA--------NPNVASYHGNLAVLYHRWGHLDSAKKHYEISLQL 746
Cdd:pfam13424   9 LAAVLRRLGRYDEALELLEKALEIarrllgpdHPLTATTLLNLGRLYLELGRYEEALELLERALAL 74
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 581-614 2.40e-04

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 38.97  E-value: 2.40e-04
                           10        20        30
                   ....*....|....*....|....*....|....
gi 564387696   581 AAAWMNLGIVQNSLKRFEEAEQSYRTAIKHRRKY 614
Cdd:smart00028   1 AEALYNLGNAYLKLGDYDEALEYYEKALELDPNN 34
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 717-748 7.42e-03

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 34.73  E-value: 7.42e-03
                           10        20        30
                   ....*....|....*....|....*....|..
gi 564387696   717 ASYHGNLAVLYHRWGHLDSAKKHYEISLQLDP 748
Cdd:smart00028   1 AEALYNLGNAYLKLGDYDEALEYYEKALELDP 32
 
Name Accession Description Interval E-value
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
506-712 1.49e-39

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 146.31  E-value: 1.49e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564387696 506 LSVCPLNAKVHYNIGKNLADQGNQTAAIKYYREAVRLNPKYVHAMNNLGNILKERNELQEAEELLSLAVQIQPDFAAAWM 585
Cdd:COG0457    1 LELDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALN 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564387696 586 NLGIVQNSLKRFEEAEQSYRTAIKHRRKYPDCYYNLGRLYADLNRHVDALNAWRNATVMKPEHSLAWNNMVILLDNTGNL 665
Cdd:COG0457   81 NLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRY 160

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*..
gi 564387696 666 AQAEAVGREALQLIPNDHSLMFSLANVLGKSQKYKESEALFLKAIKA 712
Cdd:COG0457  161 EEALELLEKLEAAALAALLAAALGEAALALAAAEVLLALLLALEQAL 207
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 517-748 6.06e-39

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 145.64  E-value: 6.06e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564387696 517 YNIGKNLADQGNQTAAIKYYREAVRLNPKYVHAMNNLGNILKERNELQEAEELLSLAVQIQPDFAAAWMNLGIVQNSLKR 596
Cdd:COG2956   12 YFKGLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGL 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564387696 597 FEEAEQSYRTAIKHRRKYPDCYYNLGRLYADLNRHVDALNAWRNATVMKPEHSLAWNNMVILLDNTGNLAQAEAVGREAL 676
Cdd:COG2956   92 LDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKAL 171

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 564387696 677 QLIPNDHSLMFSLANVLGKSQKYKESEALFLKAIKANPNVASYHGNLAVLYHRWGHLDSAKKHYEISLQLDP 748
Cdd:COG2956  172 KLDPDCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEALELLRKALELDP 243
TMTC_DUF1736 pfam08409
Protein O-mannosyl-transferase TMTC, DUF1736; This domain of unknown function is found in ...
 323-397 1.18e-38

Protein O-mannosyl-transferase TMTC, DUF1736; This domain of unknown function is found in O-mannosyl -transferases TMTC1-4, and constitutes a loop between TM7 and TM8 located in the ER lumen that contains a small hydrophobic, but not membrane-embedded helix. This loop is critical for catalysis and binding of ligands, especially the lipid-linked sugar moiety. TMTCs transfers mannosyl residues to the hydroxyl group of serine or threonine residues. The 4 members of the TMTC family are O-mannosyl-transferases acting primarily on the cadherin superfamily; each member has distinct roles in decorating the cadherin domains with O-linked mannose glycans at specific regions. These proteins also act as O-mannosyl-transferase on other proteins such as PDIA3.


Pssm-ID: 462468  Cd Length: 75  Bit Score: 137.66  E-value: 1.18e-38
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 564387696  323 GTGPPAFTEVDNPASFADSVLVRAINYNYYYSLNAWLLLCPWWLCFDWSMGCIPLIKSVGDWRVIALAALWLCLI 397
Cdd:pfam08409   1 GGQLPVFSASDNPAAFSPSLLTRTLTYNYLPALNAWLLLFPSWLCFDWSMGSIPLIESLSDPRNLATLAFYGALA 75
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
540-741 3.13e-37

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 139.76  E-value: 3.13e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564387696 540 VRLNPKYVHAMNNLGNILKERNELQEAEELLSLAVQIQPDFAAAWMNLGIVQNSLKRFEEAEQSYRTAIKHRRKYPDCYY 619
Cdd:COG0457    1 LELDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALN 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564387696 620 NLGRLYADLNRHVDALNAWRNATVMKPEHSLAWNNMVILLDNTGNLAQAEAVGREALQLIPNDHSLMFSLANVLGKSQKY 699
Cdd:COG0457   81 NLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRY 160

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|..
gi 564387696 700 KESEALFLKAIKANPNVASYHGNLAVLYHRWGHLDSAKKHYE 741
Cdd:COG0457  161 EEALELLEKLEAAALAALLAAALGEAALALAAAEVLLALLLA 202
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 480-713 7.14e-33

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 128.31  E-value: 7.14e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564387696 480 ILLINALRcviRSGEWRSEDRLFRSALSVCPLNAKVHYNIGKNLADQGNQTAAIKYYREAVRLNPKYVHAMNNLGNILKE 559
Cdd:COG2956   46 LALGNLYR---RRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGLLDRAEELLEKLLELDPDDAEALRLLAEIYEQ 122

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564387696 560 RNELQEAEELLSLAVQIQPDFAAAWMNLGIVQNSLKRFEEAEQSYRTAIKHRRKYPDCYYNLGRLYADLNRHVDALNAWR 639
Cdd:COG2956  123 EGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALE 202

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 564387696 640 NATVMKPEHSLAWNNMVILLDNTGNLAQAEAVGREALQLIPNDhSLMFSLANVLGKSQKYKESEALFLKAIKAN 713
Cdd:COG2956  203 RALEQDPDYLPALPRLAELYEKLGDPEEALELLRKALELDPSD-DLLLALADLLERKEGLEAALALLERQLRRH 275
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 501-747 1.29e-32

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 127.54  E-value: 1.29e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564387696 501 LFRSALSVCPLNAKVHYNIGKNLADQGNQTAAIKYYREAVRLNPKYVHAMNNLGNILKERNELQEAEELLSLAVQIQPDF 580
Cdd:COG2956   30 LLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGLLDRAEELLEKLLELDPDD 109

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564387696 581 AAAWMNLGIVQNSLKRFEEAEQSYRTAIKHRRKYPDCYYNLGRLYADLNRHVDALNAWRNATVMKPEHSLAWNNMVILLD 660
Cdd:COG2956  110 AEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKALKLDPDCARALLLLAELYL 189

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564387696 661 NTGNLAQAEAVGREALQLIPNDHSLMFSLANVLGKSQKYKESEALFLKAIKANPNVASYHgNLAVLYHRWGHLDSAKKHY 740
Cdd:COG2956  190 EQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEALELLRKALELDPSDDLLL-ALADLLERKEGLEAALALL 268


                 ....*..
gi 564387696 741 EISLQLD 747
Cdd:COG2956  269 ERQLRRH 275
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 474-685 1.43e-32

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 134.35  E-value: 1.43e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564387696 474 AAIILGILLINALRCVIRSGEWRSEDRLFRSALSVCPLNAKVHYNIGKNLADQGNQTAAIKYYREAVRLNPKYVHAMNNL 553
Cdd:COG3914   39 AALGLALLLLAALAEAAAAALLALAAGEAAAAAAALLLLAALLELAALLLQALGRYEEALALYRRALALNPDNAEALFNL 118

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564387696 554 GNILKERNELQEAEELLSLAVQIQPDFAAAWMNLGIVQNSLKRFEEAEQSYRTAIKHRRKYPDCYYNLGRLYADLNRHVD 633
Cdd:COG3914  119 GNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLGRLEEAIAALRRALELDPDNAEALNNLGNALQDLGRLEE 198

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
gi 564387696 634 ALNAWRNATVMKPEHSLAWNNMVILLDNTGNLAQAEAVGREALQLIPNDHSL 685
Cdd:COG3914  199 AIAAYRRALELDPDNADAHSNLLFALRQACDWEVYDRFEELLAALARGPSEL 250
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
500-639 4.97e-32

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 125.12  E-value: 4.97e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564387696 500 RLFRSALSVCPLNAKVHYNIGKNLADQGNQTAAIKYYREAVRLNPKYVHAMNNLGNILKERNELQEAEELLSLAVQIQPD 579
Cdd:COG0457   29 EDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLALQALGRYEEALEDYDKALELDPD 108

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 564387696 580 FAAAWMNLGIVQNSLKRFEEAEQSYRTAIKHRRKYPDCYYNLGRLYADLNRHVDALNAWR 639
Cdd:COG0457  109 DAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRYEEALELLE 168
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
613-769 1.71e-28

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 114.72  E-value: 1.71e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564387696 613 KYPDCYYNLGRLYADLNRHVDALNAWRNATVMKPEHSLAWNNMVILLDNTGNLAQAEAVGREALQLIPNDHSLMFSLANV 692
Cdd:COG0457    6 DDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLA 85

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 564387696 693 LGKSQKYKESEALFLKAIKANPNVASYHGNLAVLYHRWGHLDSAKKHYEISLQLDPVAVGTKENYSLLRRKLEQMQK 769
Cdd:COG0457   86 LQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRYEE 162
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 513-648 3.25e-28

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 110.28  E-value: 3.25e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564387696 513 AKVHYNIGKNLADQGNQTAAIKYYREAVRLNPKYVHAMNNLGNILKERNELQEAEELLSLAVQIQPDFAAAWMNLGIVQN 592
Cdd:COG4783    4 AEALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALL 83

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 564387696 593 SLKRFEEAEQSYRTAIKHRRKYPDCYYNLGRLYADLNRHVDALNAWRNATVMKPEH 648
Cdd:COG4783   84 KAGDYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALELDPDD 139
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 553-729 3.79e-28

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 120.48  E-value: 3.79e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564387696 553 LGNILKERNELQEAEELLSLAVQIQPDFAAAWMNLGIVQNSLKRFEEAEQSYRTAIKHRRKYPDCYYNLGRLYADLNRHV 632
Cdd:COG3914   84 AALLLQALGRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLGRLE 163

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564387696 633 DALNAWRNATVMKPEHSLAWNNMVILLDNTGNLAQAEAVGREALQLIPND---HSLMFSLANVLGKSQKYKESEALfLKA 709
Cdd:COG3914  164 EAIAALRRALELDPDNAEALNNLGNALQDLGRLEEAIAAYRRALELDPDNadaHSNLLFALRQACDWEVYDRFEEL-LAA 242

                        170       180
                 ....*....|....*....|
gi 564387696 710 IKANPNVASyhgNLAVLYHR 729
Cdd:COG3914  243 LARGPSELS---PFALLYLP 259
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 523-746 6.25e-27

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 116.63  E-value: 6.25e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564387696 523 LADQGNQTAAIKYYREAVRLNPKYVHAMNNLGNILKERNELQEAEELLSLAVQIQPDFAAAWMNLGIVQNS--------- 593
Cdd:COG3914   11 ALAAAALLAAAAAAELALAAELEAAALAAALGLALLLLAALAEAAAAALLALAAGEAAAAAAALLLLAALLelaalllqa 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564387696 594 LKRFEEAEQSYRTAIKHRRKYPDCYYNLGRLYADLNRHVDALNAWRNATVMKPEHSLAWNNMVILLDNTGNLAQAEAVGR 673
Cdd:COG3914   91 LGRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLGRLEEAIAALR 170

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 564387696 674 EALQLIPNDHSLMFSLANVLGKSQKYKESEALFLKAIKANPNVASYHGNLAVLYHRWGHLDSAKKHYEISLQL 746
Cdd:COG3914  171 RALELDPDNAEALNNLGNALQDLGRLEEAIAAYRRALELDPDNADAHSNLLFALRQACDWEVYDRFEELLAAL 243
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
491-637 1.08e-23

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 100.85  E-value: 1.08e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564387696 491 RSGEWRSEDRLFRSALSVCPLNAKVHYNIGKNLADQGNQTAAIKYYREAVRLNPKYVHAMNNLGNILKERNELQEAEELL 570
Cdd:COG0457   54 RLGRYEEALADYEQALELDPDDAEALNNLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAY 133

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 564387696 571 SLAVQIQPDFAAAWMNLGIVQNSLKRFEEAEQSYRTAIKHRRKYPDCYYNLGRLYADLNRHVDALNA 637
Cdd:COG0457  134 ERALELDPDDADALYNLGIALEKLGRYEEALELLEKLEAAALAALLAAALGEAALALAAAEVLLALL 200
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 618-748 1.79e-23

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 96.80  E-value: 1.79e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564387696 618 YYNLGRLYADLNRHVDALNAWRNATVMKPEHSLAWNNMVILLDNTGNLAQAEAVGREALQLIPNDHSLMFSLANVLGKSQ 697
Cdd:COG4783    7 LYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKAG 86

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|.
gi 564387696 698 KYKESEALFLKAIKANPNVASYHGNLAVLYHRWGHLDSAKKHYEISLQLDP 748
Cdd:COG4783   87 DYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALELDP 137
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 548-748 2.39e-23

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 105.46  E-value: 2.39e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564387696 548 HAMNNLGNILKERNELQEAEELLSLAVQIQPDFAAAWMNLGIVQNSLKRFEEAE--QSYRTAIKHRRKYPDCYYNL---- 621
Cdd:COG3914    2 AAAALLALAALAAAALLAAAAAAELALAAELEAAALAAALGLALLLLAALAEAAaaALLALAAGEAAAAAAALLLLaall 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564387696 622 ---GRLYADLNRHVDALNAWRNATVMKPEHSLAWNNMVILLDNTGNLAQAEAVGREALQLIPNDHSLMFSLANVLGKSQK 698
Cdd:COG3914   82 elaALLLQALGRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLGR 161

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|
gi 564387696 699 YKESEALFLKAIKANPNVASYHGNLAVLYHRWGHLDSAKKHYEISLQLDP 748
Cdd:COG3914  162 LEEAIAALRRALELDPDNAEALNNLGNALQDLGRLEEAIAAYRRALELDP 211
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 549-682 8.52e-22

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 91.79  E-value: 8.52e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564387696 549 AMNNLGNILKERNELQEAEELLSLAVQIQPDFAAAWMNLGIVQNSLKRFEEAEQSYRTAIKHRRKYPDCYYNLGRLYADL 628
Cdd:COG4783    6 ALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKA 85

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....
gi 564387696 629 NRHVDALNAWRNATVMKPEHSLAWNNMVILLDNTGNLAQAEAVGREALQLIPND 682
Cdd:COG4783   86 GDYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALELDPDD 139
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 491-616 1.76e-21

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 91.02  E-value: 1.76e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564387696 491 RSGEWRSEDRLFRSALSVCPLNAKVHYNIGKNLADQGNQTAAIKYYREAVRLNPKYVHAMNNLGNILKERNELQEAEELL 570
Cdd:COG4783   16 LAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKAGDYDEALALL 95

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*.
gi 564387696 571 SLAVQIQPDFAAAWMNLGIVQNSLKRFEEAEQSYRTAIkhrRKYPD 616
Cdd:COG4783   96 EKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKAL---ELDPD 138
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 580-769 1.89e-21

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 95.18  E-value: 1.89e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564387696 580 FAAAWMNLGIVQNSLKRFEEAEQSYRTAIKHRRKYPDCYYNLGRLYADLNRHVDALNAWRNATVMKPEHSLAWNNMVILL 659
Cdd:COG2956    7 AALGWYFKGLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDY 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564387696 660 DNTGNLAQAEAVGREALQLIPNDHSLMFSLANVLGKSQKYKESEALFLKAIKANPNVASYHGNLAVLYHRWGHLDSAKKH 739
Cdd:COG2956   87 LKAGLLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEA 166

                        170       180       190
                 ....*....|....*....|....*....|
gi 564387696 740 YEISLQLDPVAVGTKENYSLLRRKLEQMQK 769
Cdd:COG2956  167 LEKALKLDPDCARALLLLAELYLEQGDYEE 196
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
509-653 1.47e-20

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 91.13  E-value: 1.47e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564387696 509 CPLNAKVHYNIGKNLADQGNQTAAIKYYREAVRLNPKYVHAMNNLGNILKERNELQEAEELLSLAVQIQPDFAAAWMNLG 588
Cdd:COG4785   69 LPDLAQLYYERGVAYDSLGDYDLAIADFDQALELDPDLAEAYNNRGLAYLLLGDYDAALEDFDRALELDPDYAYAYLNRG 148

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 564387696 589 IVQNSLKRFEEAEQSYRTAIKHRRKYPDCYYNLGRLYADLNRH---VDALNAWRNATVMKPEHSLAWN 653
Cdd:COG4785  149 IALYYLGRYELAIADLEKALELDPNDPERALWLYLAERKLDPEkalALLLEDWATAYLLQGDTEEARE 216
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
644-769 5.13e-20

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 90.07  E-value: 5.13e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564387696 644 MKPEHSLAWNNMVILLDNTGNLAQAEAVGREALQLIPNDHSLMFSLANVLGKSQKYKESEALFLKAIKANPNVASYHGNL 723
Cdd:COG0457    3 LDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNL 82

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*.
gi 564387696 724 AVLYHRWGHLDSAKKHYEISLQLDPVAVGTKENYSLLRRKLEQMQK 769
Cdd:COG0457   83 GLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDE 128
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 531-649 5.71e-19

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 83.52  E-value: 5.71e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564387696 531 AAIKYYREAVRLNPKYVHAMNNLGNILKERNELQEAEELLSLAVQIQPDFAAAWMNLGIVQNSLKRFEEAEQSYRTAIKH 610
Cdd:COG4235    1 EAIARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALAL 80

                         90       100       110
                 ....*....|....*....|....*....|....*....
gi 564387696 611 RRKYPDCYYNLGRLYADLNRHVDALNAWRNATVMKPEHS 649
Cdd:COG4235   81 DPDNPEALYLLGLAAFQQGDYAEAIAAWQKLLALLPADA 119
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 510-609 1.43e-18

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 82.36  E-value: 1.43e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564387696 510 PLNAKVHYNIGKNLADQGNQTAAIKYYREAVRLNPKYVHAMNNLGNILKERNELQEAEELLSLAVQIQPDFAAAWMNLGI 589
Cdd:COG4235   14 PNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALALDPDNPEALYLLGL 93

                         90       100
                 ....*....|....*....|
gi 564387696 590 VQNSLKRFEEAEQSYRTAIK 609
Cdd:COG4235   94 AAFQQGDYAEAIAAWQKLLA 113
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 523-609 6.22e-18

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 81.55  E-value: 6.22e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564387696 523 LADQGNQTAAIKYYREAVRLNPKYVHAMNNLGNILKERNELQEAEELLSLAVQIQPDFAAAWMNLGIVQNSLKRFEEAEQ 602
Cdd:COG5010   64 YNKLGDFEESLALLEQALQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKA 143


                 ....*..
gi 564387696 603 SYRTAIK 609
Cdd:COG5010  144 ALQRALG 150
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 599-715 9.77e-18

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 80.05  E-value: 9.77e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564387696 599 EAEQSYRTAIKHRRKYPDCYYNLGRLYADLNRHVDALNAWRNATVMKPEHSLAWNNMVILLDNTGNLAQAEAVGREALQL 678
Cdd:COG4235    1 EAIARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALAL 80

                         90       100       110
                 ....*....|....*....|....*....|....*..
gi 564387696 679 IPNDHSLMFSLANVLGKSQKYKESEALFLKAIKANPN 715
Cdd:COG4235   81 DPDNPEALYLLGLAAFQQGDYAEAIAAWQKLLALLPA 117
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 565-682 1.54e-17

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 79.66  E-value: 1.54e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564387696 565 EAEELLSLAVQIQPDFAAAWMNLGIVQNSLKRFEEAEQSYRTAIKHRRKYPDCYYNLGRLYADLNRHVDALNAWRNATVM 644
Cdd:COG4235    1 EAIARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALAL 80

                         90       100       110
                 ....*....|....*....|....*....|....*...
gi 564387696 645 KPEHSLAWNNMVILLDNTGNLAQAEAVGREALQLIPND 682
Cdd:COG4235   81 DPDNPEALYLLGLAAFQQGDYAEAIAAWQKLLALLPAD 118
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
523-613 1.73e-17

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 78.29  E-value: 1.73e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564387696 523 LADQGNQTAAIKYYREAVRLNPKYVHAMNNLGNILKERNELQEAEELLSlAVQIQPDFAAAWMNLGIVQNSLKRFEEAEQ 602
Cdd:COG3063    2 YLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIALEK-ALKLDPNNAEALLNLAELLLELGDYDEALA 80

                         90
                 ....*....|.
gi 564387696 603 SYRTAIKHRRK 613
Cdd:COG3063   81 YLERALELDPS 91
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 501-748 1.53e-16

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 84.36  E-value: 1.53e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564387696  501 LFRSALSVCPLNAKVHYNIGKNLADQGNQTAAIKYYREAVRLNPKYVHAMNNLGNILKERNELQEAEELLSLAVQIQPDF 580
Cdd:TIGR02917 589 ILNEAADAAPDSPEAWLMLGRAQLAAGDLNKAVSSFKKLLALQPDSALALLLLADAYAVMKNYAKAITSLKRALELKPDN 668

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564387696  581 AAAWMNLGIVQNSLKRFEEAEQSYRTAIKHRRKYPDCYYNLGRLYADLNRHVDALNAWRNATVMKPEHSLAWNNMVILLD 660
Cdd:TIGR02917 669 TEAQIGLAQLLLAAKRTESAKKIAKSLQKQHPKAALGFELEGDLYLRQKDYPAAIQAYRKALKRAPSSQNAIKLHRALLA 748

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564387696  661 NtGNLAQAEAVGREALQLIPNDHSLMFSLANVLGKSQKYKESEALFLKAIKANPNVASYHGNLAVLYHRwghLDSAK--K 738
Cdd:TIGR02917 749 S-GNTAEAVKTLEAWLKTHPNDAVLRTALAELYLAQKDYDKAIKHYQTVVKKAPDNAVVLNNLAWLYLE---LKDPRalE 824

                         250
                  ....*....|
gi 564387696  739 HYEISLQLDP 748
Cdd:TIGR02917 825 YAERALKLAP 834
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
500-641 8.71e-16

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 77.26  E-value: 8.71e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564387696 500 RLFRSALSVCPLNAKVHYNIGKNLADQGNQTAAIKYYREAVRlNPKYVHAMNNLGNILKERNELQEAEELLSLAVQIQPD 579
Cdd:COG4785   27 AALLFAAVLALAIALADLALALAAAALAAAALAAERIDRALA-LPDLAQLYYERGVAYDSLGDYDLAIADFDQALELDPD 105

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 564387696 580 FAAAWMNLGIVQNSLKRFEEAEQSYRTAIKHRRKYPDCYYNLGRLYADLNRHVDALNAWRNA 641
Cdd:COG4785  106 LAEAYNNRGLAYLLLGDYDAALEDFDRALELDPDYAYAYLNRGIALYYLGRYELAIADLEKA 167
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 523-646 8.71e-16

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 75.38  E-value: 8.71e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564387696 523 LADQGNQTAAIKYYREAVRLNPKYVHAMNNLGNILKERNELQEAEELLSLAVQIQPDFAAAWMNLGIVQNSLKRFEEAEQ 602
Cdd:COG5010   30 ALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPNNPELYYNLALLYSRSGDKDEAKE 109

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....
gi 564387696 603 SYRTAIKHRRKYPDCYYNLGRLYADLNRHVDALNAWRNATVMKP 646
Cdd:COG5010  110 YYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAALQRALGTSP 153
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 502-748 1.78e-15

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 80.90  E-value: 1.78e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564387696  502 FRSALSVCPLNAKVHYNIGKNLADQGNQTAAIKYYREAVRLNPKYVHAMN------------------------------ 551
Cdd:TIGR02917 488 FEKALSIEPDFFPAAANLARIDIQEGNPDDAIQRFEKVLTIDPKNLRAILalaglylrtgneeeavawlekaaelnpqei 567

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564387696  552 ----NLGNILKERNELQEAEELLSLAVQIQPDFAAAWMNLGI----------------------------------VQNS 593
Cdd:TIGR02917 568 epalALAQYYLGKGQLKKALAILNEAADAAPDSPEAWLMLGRaqlaagdlnkavssfkkllalqpdsalalllladAYAV 647

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564387696  594 LKRFEEAEQSYRTAIKHRRKYPDCYYNLGRLYADLNRHVDALNAWRNATVMKPEHS-----LAWNNMVIlldntGNLAQA 668
Cdd:TIGR02917 648 MKNYAKAITSLKRALELKPDNTEAQIGLAQLLLAAKRTESAKKIAKSLQKQHPKAAlgfelEGDLYLRQ-----KDYPAA 722

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564387696  669 EAVGREALQLIPNDHSLMfSLANVLGKSQKYKESEALFLKAIKANPNVASYHGNLAVLYHRWGHLDSAKKHYEISLQLDP 748
Cdd:TIGR02917 723 IQAYRKALKRAPSSQNAI-KLHRALLASGNTAEAVKTLEAWLKTHPNDAVLRTALAELYLAQKDYDKAIKHYQTVVKKAP 801
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
556-647 2.43e-15

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 72.13  E-value: 2.43e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564387696 556 ILKERNELQEAEELLSLAVQIQPDFAAAWMNLGIVQNSLKRFEEAEQsYRTAIKHRRKYPDCYYNLGRLYADLNRHVDAL 635
Cdd:COG3063    1 LYLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIA-LEKALKLDPNNAEALLNLAELLLELGDYDEAL 79

                         90
                 ....*....|..
gi 564387696 636 NAWRNATVMKPE 647
Cdd:COG3063   80 AYLERALELDPS 91
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 657-750 2.45e-15

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 74.23  E-value: 2.45e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564387696 657 ILLDNTGNLAQAEAVGREALQLIPNDHSLMFSLANVLGKSQKYKESEALFLKAIKANPNVASYHGNLAVLYHRWGHLDSA 736
Cdd:COG5010   62 NLYNKLGDFEESLALLEQALQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEA 141

                         90
                 ....*....|....
gi 564387696 737 KKHYEISLQLDPVA 750
Cdd:COG5010  142 KAALQRALGTSPLK 155
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 531-680 4.00e-15

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 73.46  E-value: 4.00e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564387696 531 AAIKYYREAVRLNPKYVHAMNNLGNILKERNELQEAEELLSLAVQIQPDFAAAWMNLGIVQNSLKRFEEAEQSYRTAIKH 610
Cdd:COG5010    4 LEGFDRLPLYLLLLTKLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQL 83

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564387696 611 RRKYPDCYYNLGRLYADLNRHVDALNAWRNATVMKPEHSLAWNNMVILLDNTGNLAQAEAVGREALQLIP 680
Cdd:COG5010   84 DPNNPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAALQRALGTSP 153
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
511-682 4.80e-15

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 74.95  E-value: 4.80e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564387696 511 LNAKVHYNIGKNLADQGNQTAAIKYYREAVRLNPKYVHAMNNLGNILKERNELQEAEELLSLAvQIQPDFAAAWMNLGIV 590
Cdd:COG4785    4 LALALLLALALAAAAASKAAILLAALLFAAVLALAIALADLALALAAAALAAAALAAERIDRA-LALPDLAQLYYERGVA 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564387696 591 QNSLKRFEEAEQSYRTAIKHRRKYPDCYYNLGRLYADLNRHVDALNAWRNATVMKPEHSLAWNNMVILLDNTGNLAQAEA 670
Cdd:COG4785   83 YDSLGDYDLAIADFDQALELDPDLAEAYNNRGLAYLLLGDYDAALEDFDRALELDPDYAYAYLNRGIALYYLGRYELAIA 162

                        170
                 ....*....|..
gi 564387696 671 VGREALQLIPND 682
Cdd:COG4785  163 DLEKALELDPND 174
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
502-608 5.54e-15

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 74.95  E-value: 5.54e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564387696 502 FRSALSVCPLNAKVHYNIGKNLADQGNQTAAIKYYREAVRLNPKYVHAMNNLGNILKERNELQEAEELLSLAVQIQPDFA 581
Cdd:COG4785   96 FDQALELDPDLAEAYNNRGLAYLLLGDYDAALEDFDRALELDPDYAYAYLNRGIALYYLGRYELAIADLEKALELDPNDP 175

                         90       100
                 ....*....|....*....|....*..
gi 564387696 582 AAWMNLGIVQnSLKRFEEAEQSYRTAI 608
Cdd:COG4785  176 ERALWLYLAE-RKLDPEKALALLLEDW 201
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 470-748 3.73e-14

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 76.66  E-value: 3.73e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564387696  470 KKPVAAIILGILLINALRcvirSGEWRSEDRLFRSALSVCPLNAKVHYNIGKNLADQGNQTAAIKYYREAVRLNPKYVHA 549
Cdd:TIGR02917 120 DDEGAAELLALRGLAYLG----LGQLELAQKSYEQALAIDPRSLYAKLGLAQLALAENRFDEARALIDEVLTADPGNVDA 195

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564387696  550 MNNLGNILKERNELQEAEELLSLAVQIQPDFAAAWMNLGIVQNSLKRFEEAEQSYRTAIKHRRKYPDCYYNLGRLYADLN 629
Cdd:TIGR02917 196 LLLKGDLLLSLGNIELALAAYRKAIALRPNNIAVLLALATILIEAGEFEEAEKHADALLKKAPNSPLAHYLKALVDFQKK 275

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564387696  630 RHVDALNAWRNATVMKPEHSLAWNNMVILLDNTGNLAQAEAVGREALQLIPNDHSLMFSLANVLGKSQKYKESEALFLKA 709
Cdd:TIGR02917 276 NYEDARETLQDALKSAPEYLPALLLAGASEYQLGNLEQAYQYLNQILKYAPNSHQARRLLASIQLRLGRVDEAIATLSPA 355

                         250       260       270
                  ....*....|....*....|....*....|....*....
gi 564387696  710 IKANPNVASYHGNLAVLYHRWGHLDSAKKHYEISLQLDP 748
Cdd:TIGR02917 356 LGLDPDDPAALSLLGEAYLALGDFEKAAEYLAKATELDP 394
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 501-748 5.93e-14

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 75.89  E-value: 5.93e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564387696  501 LFRSALSVCPLNAKVHYNIGKNLADQGNQTAAIKYYREAVRLNPKYVHAMNNLGNILKERNELQEA-EELLSLAVQIQPD 579
Cdd:TIGR02917  44 QLKNALQKDPNDAEARFLLGKIYLALGDYAAAEKELRKALSLGYPKNQVLPLLARAYLLQGKFQQVlDELPGKTLLDDEG 123

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564387696  580 FAAAWMNLGIVQNSLKRFEEAEQSYRTAIKHRRKYPDCYYNLGRLYADLNRHVDALNAWRNATVMKPEHSLAWNNMVILL 659
Cdd:TIGR02917 124 AAELLALRGLAYLGLGQLELAQKSYEQALAIDPRSLYAKLGLAQLALAENRFDEARALIDEVLTADPGNVDALLLKGDLL 203

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564387696  660 DNTGNLAQAEAVGREALQLIPNDHSLMFSLANVLGKSQKYKESEALFLKAIKANPNVASYHGNLAVLYHRWGHLDSAKKH 739
Cdd:TIGR02917 204 LSLGNIELALAAYRKAIALRPNNIAVLLALATILIEAGEFEEAEKHADALLKKAPNSPLAHYLKALVDFQKKNYEDARET 283


                  ....*....
gi 564387696  740 YEISLQLDP 748
Cdd:TIGR02917 284 LQDALKSAP 292
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
658-750 1.03e-13

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 67.50  E-value: 1.03e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564387696 658 LLDNTGNLAQAEAVGREALQLIPNDHSLMFSLANVLGKSQKYKESEAlFLKAIKANPNVASYHGNLAVLYHRWGHLDSAK 737
Cdd:COG3063    1 LYLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIA-LEKALKLDPNNAEALLNLAELLLELGDYDEAL 79

                         90
                 ....*....|...
gi 564387696 738 KHYEISLQLDPVA 750
Cdd:COG3063   80 AYLERALELDPSA 92
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 467-738 2.44e-13

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 73.96  E-value: 2.44e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564387696  467 TKKKKPVAAIILGILLINAlrcvirsGEWRSEDRLFRSALSVCPLNAKVHYNIGKNLADQGNQTAAIKYYREAVRLNPKY 546
Cdd:TIGR02917 596 AAPDSPEAWLMLGRAQLAA-------GDLNKAVSSFKKLLALQPDSALALLLLADAYAVMKNYAKAITSLKRALELKPDN 668

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564387696  547 VHAMNNLGNILKERNELQEAEELLSLAVQIQPDFAAAWMNLGIVQNSLKRFEEAEQSYRTAIK-----------HR---- 611
Cdd:TIGR02917 669 TEAQIGLAQLLLAAKRTESAKKIAKSLQKQHPKAALGFELEGDLYLRQKDYPAAIQAYRKALKrapssqnaiklHRalla 748

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564387696  612 ---------------RKYPD---CYYNLGRLYADLNRHVDALNAWRNATVMKPEHSLAWNNMVILLDNTGNlAQAEAVGR 673
Cdd:TIGR02917 749 sgntaeavktleawlKTHPNdavLRTALAELYLAQKDYDKAIKHYQTVVKKAPDNAVVLNNLAWLYLELKD-PRALEYAE 827

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 564387696  674 EALQLIPNDHSLMFSLANVLGKSQKYKESEALFLKAIKANPNVASYHGNLAVLYHRWGHLDSAKK 738
Cdd:TIGR02917 828 RALKLAPNIPAILDTLGWLLVEKGEADRALPLLRKAVNIAPEAAAIRYHLALALLATGRKAEARK 892
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 440-578 3.12e-13

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 68.06  E-value: 3.12e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564387696 440 VAERVLYLPSAGYCMLLTFGFGTLSRHTKKKKPVAAIILGILLINALRCVIRSGEWRSEDRLFRSALSVCPLNAKVHYNI 519
Cdd:COG5010   15 LLLTKLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPNNPELYYNL 94

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 564387696 520 GKNLADQGNQTAAIKYYREAVRLNPKYVHAMNNLGNILKERNELQEAEELLSLAVQIQP 578
Cdd:COG5010   95 ALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAALQRALGTSP 153
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
490-579 5.67e-13

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 65.19  E-value: 5.67e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564387696 490 IRSGEWRSEDRLFRSALSVCPLNAKVHYNIGKNLADQGNQTAAIKyYREAVRLNPKYVHAMNNLGNILKERNELQEAEEL 569
Cdd:COG3063    3 LKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIA-LEKALKLDPNNAEALLNLAELLLELGDYDEALAY 81

                         90
                 ....*....|
gi 564387696 570 LSLAVQIQPD 579
Cdd:COG3063   82 LERALELDPS 91
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 563-714 8.92e-13

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 66.52  E-value: 8.92e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564387696 563 LQEAEELLSLAVQIQPDFAAAWMNLGIVQNSLKRFEEAEQSYRTAIKHRRKYPDCYYNLgrlYADLNRHVDALNAWRNAT 642
Cdd:COG5010    5 EGFDRLPLYLLLLTKLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNL---YNKLGDFEESLALLEQAL 81

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 564387696 643 VMKPEHSLAWNNMVILLDNTGNLAQAEAVGREALQLIPNDHSLMFSLANVLGKSQKYKESEALFLKAIKANP 714
Cdd:COG5010   82 QLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAALQRALGTSP 153
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 651-769 9.39e-13

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 65.98  E-value: 9.39e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564387696 651 AWNNMVILLDNTGNLAQAEAVGREALQLIPNDHSLMFSLANVLGKSQKYKESEALFLKAIKANPNVASYHGNLAVLYHRW 730
Cdd:COG4783    6 ALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKA 85

                         90       100       110
                 ....*....|....*....|....*....|....*....
gi 564387696 731 GHLDSAKKHYEISLQLDPVAVGTKENYSLLRRKLEQMQK 769
Cdd:COG4783   86 GDYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDE 124
type_IV_pilW TIGR02521
type IV pilus biogenesis/stability protein PilW; Members of this family are designated PilF ...
 513-708 1.04e-11

type IV pilus biogenesis/stability protein PilW; Members of this family are designated PilF and PilW. This outer membrane protein is required both for pilus stability and for pilus function such as adherence to human cells. Members of this family contain copies of the TPR (tetratricopeptide repeat) domain.


Pssm-ID: 131573 [Multi-domain]  Cd Length: 234  Bit Score: 65.44  E-value: 1.04e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564387696  513 AKVHYNIGKNLADQGNQTAAIKYYREAVRLNPKYVHAMNNLGNILKERNELQEAEELLSLAVQIQPDFAAAWMNLGIVQN 592
Cdd:TIGR02521  31 AKIRVQLALGYLEQGDLEVAKENLDKALEHDPDDYLAYLALALYYQQLGELEKAEDSFRRALTLNPNNGDVLNNYGTFLC 110

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564387696  593 SLKRFEEAEQSYRTAIKhRRKYP---DCYYNLGRLYADLNRHVDALNAWRNATVMKPEHSLAWNNMVILLDNTGNLAQAE 669
Cdd:TIGR02521 111 QQGKYEQAMQQFEQAIE-DPLYPqpaRSLENAGLCALKAGDFDKAEKYLTRALQIDPQRPESLLELAELYYLRGQYKDAR 189

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....
gi 564387696  670 A-----VGREALQliPNDHSLMFSLANVLGKSQKYKESEALFLK 708
Cdd:TIGR02521 190 AyleryQQTYNQT--AESLWLGIRIARALGDVAAAQRYGAQLQK 231
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 526-748 1.08e-11

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 68.57  E-value: 1.08e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564387696  526 QGNQTAAIKYYREAVRLNPKYVHAMNNLGNILKERNELQEAEELLSLAVQIQPDFAAAWMNLGIVQNSLKRFEEAEQSYR 605
Cdd:TIGR02917 342 LGRVDEAIATLSPALGLDPDDPAALSLLGEAYLALGDFEKAAEYLAKATELDPENAAARTQLGISKLSQGDPSEAIADLE 421

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564387696  606 TAIKHRRKYPDCYYNLGRLYADLNRHVDALNAWRNATVMKPEHSLAWNNMVILLDNTGNLAQAEAVGREALQLIPNDHSL 685
Cdd:TIGR02917 422 TAAQLDPELGRADLLLILSYLRSGQFDKALAAAKKLEKKQPDNASLHNLLGAIYLGKGDLAKAREAFEKALSIEPDFFPA 501

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 564387696  686 MFSLANVLGKSQKYKESEALFLKAIKANPNVASYHGNLAVLYHRWGHLDSAKKHYEISLQLDP 748
Cdd:TIGR02917 502 AANLARIDIQEGNPDDAIQRFEKVLTIDPKNLRAILALAGLYLRTGNEEEAVAWLEKAAELNP 564
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
624-715 1.48e-11

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 61.34  E-value: 1.48e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564387696 624 LYADLNRHVDALNAWRNATVMKPEHSLAWNNMVILLDNTGNLAQAEAVgREALQLIPNDHSLMFSLANVLGKSQKYKESE 703
Cdd:COG3063    1 LYLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIAL-EKALKLDPNNAEALLNLAELLLELGDYDEAL 79

                         90
                 ....*....|..
gi 564387696 704 ALFLKAIKANPN 715
Cdd:COG3063   80 AYLERALELDPS 91
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
500-639 1.64e-11

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 65.03  E-value: 1.64e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564387696 500 RLFRSALSVCPLNAKVHYNIGKNLADQGNQTAAIKYYREAVRLNPKYVHAMNNLGNILKERNELQEAEELLSLAVQIQPD 579
Cdd:COG0457   97 EDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRYEEALELLEKLEAAALA 176

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 564387696 580 FAAAWMNLGIVQNSLKRFEEAEQSYRTAIKHRRKYPDCYYNLGRLYADLNRHVDALNAWR 639
Cdd:COG0457  177 ALLAAALGEAALALAAAEVLLALLLALEQALRKKLAILTLAALAELLLLALALLLALRLA 236
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 500-580 7.77e-11

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 60.59  E-value: 7.77e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564387696 500 RLFRSALSVCPLNAKVHYNIGKNLADQGNQTAAIKYYREAVRLNPKYVHAMNNLGNILKERNELQEAEELLSLAVQIQPD 579
Cdd:COG4783   59 VLLHEALELDPDEPEARLNLGLALLKAGDYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALELDPD 138


                 .
gi 564387696 580 F 580
Cdd:COG4783  139 D 139
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
676-769 1.27e-10

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 62.33  E-value: 1.27e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564387696 676 LQLIPNDHSLMFSLANVLGKSQKYKESEALFLKAIKANPNVASYHGNLAVLYHRWGHLDSAKKHYEISLQLDPVAVGTKE 755
Cdd:COG0457    1 LELDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALN 80

                         90
                 ....*....|....
gi 564387696 756 NYSLLRRKLEQMQK 769
Cdd:COG0457   81 NLGLALQALGRYEE 94
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
585-766 4.77e-10

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 60.31  E-value: 4.77e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564387696 585 MNLGIVQNSLKRFEEAEQSYRTAIKHRRKYPDCYYNLGRLYADLNRHVDALNAWR------NATVMKPEHSLAWNNMVIL 658
Cdd:COG4785    3 ALALALLLALALAAAAASKAAILLAALLFAAVLALAIALADLALALAAAALAAAAlaaeriDRALALPDLAQLYYERGVA 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564387696 659 LDNTGNLAQAEAVGREALQLIPNDHSLMFSLANVLGKSQKYKESEALFLKAIKANPNVASYHGNLAVLYHRWGHLDSAKK 738
Cdd:COG4785   83 YDSLGDYDLAIADFDQALELDPDLAEAYNNRGLAYLLLGDYDAALEDFDRALELDPDYAYAYLNRGIALYYLGRYELAIA 162

                        170       180
                 ....*....|....*....|....*...
gi 564387696 739 HYEISLQLDPVAVGTKENYSLLRRKLEQ 766
Cdd:COG4785  163 DLEKALELDPNDPERALWLYLAERKLDP 190
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 500-596 2.86e-09

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 55.78  E-value: 2.86e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564387696 500 RLFRSALSVCPLNAKVHYNIGKNLADQGNQTAAIKYYREAVRLNPKYVHAMNNLGNILKERNELQEAEELLSLAVQIQPD 579
Cdd:COG4235   38 AAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALALDPDNPEALYLLGLAAFQQGDYAEAIAAWQKLLALLPA 117

                         90
                 ....*....|....*..
gi 564387696 580 FAAAWMnlgiVQNSLKR 596
Cdd:COG4235  118 DAPARL----LEASIAE 130
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 664-769 3.78e-09

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 56.12  E-value: 3.78e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564387696 664 NLAQAEAVGREALQLIPNDHSLMFSLANVLGKSQKYKESEALFLKAIKANPNVASYHGNLAVLYHRWGHLDSAKKHYEIS 743
Cdd:COG5010   35 NNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKA 114

                         90       100
                 ....*....|....*....|....*.
gi 564387696 744 LQLDPVAVGTKENYSLLRRKLEQMQK 769
Cdd:COG5010  115 LALSPDNPNAYSNLAALLLSLGQDDE 140
C39_PA2778_fam NF033920
PA2778 family cysteine peptidase; Members of this family are MEROPS classification C39 family ...
 523-609 4.31e-09

PA2778 family cysteine peptidase; Members of this family are MEROPS classification C39 family cysteine peptidases, a group that includes many processing enzyme for peptide natural products such as lantibiotics and other bacteriocins. This family, more specifically, includes PA2778 as found in Pseudomonas aeruginosa. All members of the defining seed alignment are encoded in the vicinity of a homolog of PA2779 (see HMM NF033919). Note that the C-terminal region consists largely of tetratricopeptide repeats (TPR), so classification using this HMM must be based on comparing the top domain score to the second gathering threshold (GA2).


Pssm-ID: 468245 [Multi-domain]  Cd Length: 255  Bit Score: 57.95  E-value: 4.31e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564387696 523 LADQGNQTAAIKYYREAVRLNPKYVHAMNNLGNILKERNELQEAEELLSLAVQIQPDFAAAWMNLGIVQNSLKRFEEAEQ 602
Cdd:NF033920 166 LEQTGQPEAALAAYQTATKRWPDSWLAYFGLGNAAYAAGDYAAAAAAFRQAVERHPDSAAAWNNLAYALAAQGCTAQARA 245


                 ....*..
gi 564387696 603 SYRTAIK 609
Cdd:NF033920 246 AAECALA 252
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 521-616 9.67e-09

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 53.84  E-value: 9.67e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564387696 521 KNLADQGNQTAAIKYYREAVRLNPKYVH---AMNNLGNILKERNELQEAEELLSLAVQIQPD---FAAAWMNLGIVQNSL 594
Cdd:COG1729    1 KALLKAGDYDEAIAAFKAFLKRYPNSPLapdALYWLGEAYYALGDYDEAAEAFEKLLKRYPDspkAPDALLKLGLSYLEL 80

                         90       100
                 ....*....|....*....|..
gi 564387696 595 KRFEEAEQSYRTAIKhrrKYPD 616
Cdd:COG1729   81 GDYDKARATLEELIK---KYPD 99
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 559-651 1.67e-08

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 53.07  E-value: 1.67e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564387696 559 ERNELQEAEELLSLAVQIQPD---FAAAWMNLGIVQNSLKRFEEAEQSYRTAIKHR---RKYPDCYYNLGRLYADLNRHV 632
Cdd:COG1729    5 KAGDYDEAIAAFKAFLKRYPNsplAPDALYWLGEAYYALGDYDEAAEAFEKLLKRYpdsPKAPDALLKLGLSYLELGDYD 84

                         90
                 ....*....|....*....
gi 564387696 633 DALNAWRNATVMKPEHSLA 651
Cdd:COG1729   85 KARATLEELIKKYPDSEAA 103
PRK11447 PRK11447
cellulose synthase subunit BcsC; Provisional
 503-717 3.32e-08

cellulose synthase subunit BcsC; Provisional


Pssm-ID: 183140 [Multi-domain]  Cd Length: 1157  Bit Score: 57.40  E-value: 3.32e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564387696  503 RSALSVCPLNAKVHYNIGKNLADQGNQTAAIKYYREAVRLNP---------------KYVHAMNNLGNILKErNELQEAE 567
Cdd:PRK11447  293 QQAVRANPKDSEALGALGQAYSQQGDRARAVAQFEKALALDPhssnrdkwesllkvnRYWLLIQQGDAALKA-NNLAQAE 371

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564387696  568 ELLSLAVQIQPDFAAAWMNLGIVQNSLKRFEEAEQSYRTAikhRRKYPDcyyN------LGRLY-------ADlnRHVDA 634
Cdd:PRK11447  372 RLYQQARQVDNTDSYAVLGLGDVAMARKDYAAAERYYQQA---LRMDPG---NtnavrgLANLYrqqspekAL--AFIAS 443

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564387696  635 LNAWRNATVMKPEHSLAwNNMVIL----LDNTGNLAQAEAVGREALQLIPNDHSLMFSLANVLGKSQKYKESEALFLKAI 710
Cdd:PRK11447  444 LSASQRRSIDDIERSLQ-NDRLAQqaeaLENQGKWAQAAELQRQRLALDPGSVWLTYRLAQDLRQAGQRSQADALMRRLA 522


                  ....*..
gi 564387696  711 KANPNVA 717
Cdd:PRK11447  523 QQKPNDP 529
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 490-748 4.77e-08

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 56.63  E-value: 4.77e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564387696  490 IRSGEWRSEDRLFRSALSVCPLNAKVHYNIGKNLADQGNQTAAIKYYREAVRLNPKYVHAMNNLGNILKERNELQEAeel 569
Cdd:TIGR02917 374 LALGDFEKAAEYLAKATELDPENAAARTQLGISKLSQGDPSEAIADLETAAQLDPELGRADLLLILSYLRSGQFDKA--- 450

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564387696  570 LSLAVQI---QPDFAAAWMNLGIVQNSLKRFEEAEQSYRTAIKHRRKYPDCYYNLGRLYADLNR---------------- 630
Cdd:TIGR02917 451 LAAAKKLekkQPDNASLHNLLGAIYLGKGDLAKAREAFEKALSIEPDFFPAAANLARIDIQEGNpddaiqrfekvltidp 530

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564387696  631 -HVDALNAW-----RNAtvmKPEHSLAWNNMVILLDNT---------------GNLAQAEAVGREALQLIPNDHSLMFSL 689
Cdd:TIGR02917 531 kNLRAILALaglylRTG---NEEEAVAWLEKAAELNPQeiepalalaqyylgkGQLKKALAILNEAADAAPDSPEAWLML 607

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 564387696  690 ANVLGKSQKYKESEALFLKAIKANPNVASYHGNLAVLYHRWGHLDSAKKHYEISLQLDP 748
Cdd:TIGR02917 608 GRAQLAAGDLNKAVSSFKKLLALQPDSALALLLLADAYAVMKNYAKAITSLKRALELKP 666
ACL4-like cd24142
Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 ...
 522-608 7.25e-08

Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 (ACL4) acts as a chaperone for the L4 ribosomal subunit, encoded by RPL4A and RPL4B, and is required for hierarchical ribosome assembly. It is required for the soluble expression of newly synthesized RPL4 and for the protection of RPL4 from the Tom1-dependent cellular degradation machinery. ACL4 shields ribosomal protein L4 until timely release and insertion into the pre-ribosome is possible, once ribosomal protein L18 is present.


Pssm-ID: 467942 [Multi-domain]  Cd Length: 306  Bit Score: 54.94  E-value: 7.25e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564387696 522 NLADQGNQTAAIKYYREAVRLNPKYVHAMNNLGNILKERNELQEAEELLSLAVQIQPD-FAAAWMNLG-IVQNslkrfEE 599
Cdd:cd24142    9 ELLDQGNFELALKFLQRALELEPNNVEALELLGEILLELGDVEEAREVLLRAIELDPDgGYEKYLYLGqLSGG-----EE 83


                 ....*....
gi 564387696 600 AEQSYRTAI 608
Cdd:cd24142   84 ALQYYEKGI 92
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 491-583 9.85e-08

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 50.76  E-value: 9.85e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564387696 491 RSGEWRSEDRLFRSALSVCP---LNAKVHYNIGKNLADQGNQTAAIKYYREAVRLNP---KYVHAMNNLGNILKERNELQ 564
Cdd:COG1729    5 KAGDYDEAIAAFKAFLKRYPnspLAPDALYWLGEAYYALGDYDEAAEAFEKLLKRYPdspKAPDALLKLGLSYLELGDYD 84

                         90
                 ....*....|....*....
gi 564387696 565 EAEELLSLAVQIQPDFAAA 583
Cdd:COG1729   85 KARATLEELIKKYPDSEAA 103
HemYx COG3071
Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to ...
 523-748 1.11e-07

Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to protoporphyrinogen oxidase HemY) [Function unknown];


Pssm-ID: 442305 [Multi-domain]  Cd Length: 323  Bit Score: 54.53  E-value: 1.11e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564387696 523 LADQGNQTAAIKYYREAVRLNPKYVHAMNNLGNILKERNELQEAEELLSLAVQ---IQPDFAAAWMN---LGIVQNSLKR 596
Cdd:COG3071   95 LLDQGQAEQALATLEALRAGAPRHPQVLRLLLQAYRQLGDWEELLELLPALRKhkaLSAEEAQALERrayLGLLRQAARD 174

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564387696 597 FEEAEQSYRTAIKHRRKYPDCYYNLGRLYADLNRHVDALNAWRNAtvmkpeHSLAWNNMVILL---DNTGNLAQAEAVGR 673
Cdd:COG3071  175 AEALKALWKALPRAERRDPELAAAYARALIALGDHDEAERLLREA------LKRQWDPRLVRLygrLQGGDPAKQLKRAE 248

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 564387696 674 EALQLIPNDHSLMFSLANVLGKSQKYKESEALFLKAIKANPNVASYHgNLAVLYHRWGHLDSAKKHYEISLQLDP 748
Cdd:COG3071  249 KWLKKHPNDPDLLLALGRLCLRNQLWGKAREYLEAALALRPSAEAYA-ELARLLEQLGDPEEAAEHYRKALALAL 322
HemYx COG3071
Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to ...
 526-771 1.76e-07

Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to protoporphyrinogen oxidase HemY) [Function unknown];


Pssm-ID: 442305 [Multi-domain]  Cd Length: 323  Bit Score: 53.76  E-value: 1.76e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564387696 526 QGNQTAAIKYYREAVRLNPKYVHAMNNL-GNILKERNELQEAEELLSLAVQIQPDFAAAWMNLGIVQNSLKRFEEAEQSY 604
Cdd:COG3071   63 LGDYERRDEYLAQALELAPEAELAVLLTrAELLLDQGQAEQALATLEALRAGAPRHPQVLRLLLQAYRQLGDWEELLELL 142

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564387696 605 RTAIKHRRKYPDCYYNLGR-----LYADLNRHVDALNAWRN----ATVMKPEHSLAwnnMVILLDNTGNLAQAEAVGREA 675
Cdd:COG3071  143 PALRKHKALSAEEAQALERraylgLLRQAARDAEALKALWKalprAERRDPELAAA---YARALIALGDHDEAERLLREA 219

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564387696 676 LQLIPNDhslmfSLANVLGKSQ--KYKESEALFLKAIKANPNVASYHGNLAVLYHRWGHLDSAKKHYEISLQLDPVAvgt 753
Cdd:COG3071  220 LKRQWDP-----RLVRLYGRLQggDPAKQLKRAEKWLKKHPNDPDLLLALGRLCLRNQLWGKAREYLEAALALRPSA--- 291

                        250
                 ....*....|....*...
gi 564387696 754 kENYSLLRRKLEQMQKKD 771
Cdd:COG3071  292 -EAYAELARLLEQLGDPE 308
TPR_19 pfam14559
Tetratricopeptide repeat;
526-585 5.70e-07

Tetratricopeptide repeat;


Pssm-ID: 434038 [Multi-domain]  Cd Length: 65  Bit Score: 47.19  E-value: 5.70e-07
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 564387696  526 QGNQTAAIKYYREAVRLNPKYVHAMNNLGNILKERNELQEAEELLSLAVQIQPDFAAAWM 585
Cdd:pfam14559   1 EGDYAEALELLEQALAEDPDNAEARLGLAEALLALGRLDEAEALLAALPAADPDDPRYAA 60
PRK02603 PRK02603
photosystem I assembly protein Ycf3; Provisional
 515-575 1.36e-06

photosystem I assembly protein Ycf3; Provisional


Pssm-ID: 179448 [Multi-domain]  Cd Length: 172  Bit Score: 49.29  E-value: 1.36e-06
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 564387696 515 VHYNIGKNLADQGNQTAAIKYYREAVRLNPKYVHAMNNLGNIL-------KERNELQEAEELLSLAVQ 575
Cdd:PRK02603  74 ILYNMGIIYASNGEHDKALEYYHQALELNPKQPSALNNIAVIYhkrgekaEEAGDQDEAEALFDKAAE 141
TPR_16 pfam13432
Tetratricopeptide repeat; This family is found predominantly at the C-terminus of ...
 517-579 2.46e-06

Tetratricopeptide repeat; This family is found predominantly at the C-terminus of transglutaminase enzyme core regions.


Pssm-ID: 433202 [Multi-domain]  Cd Length: 68  Bit Score: 45.40  E-value: 2.46e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 564387696  517 YNIGKNLADQGNQTAAIKYYREAVRLN---PKYVHAMNNLGNILKERNELQEAEELLSLAVQIQPD 579
Cdd:pfam13432   1 LALARAALRAGDYDDAAAALEAALARFpesPDAAAALLLLGLAALRQGRLAEAAAAYRAALRAAPG 66
TPR_12 pfam13424
Tetratricopeptide repeat;
549-613 2.66e-06

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 45.84  E-value: 2.66e-06
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 564387696  549 AMNNLGNILKERNELQEAEELLSLAVQIQ--------PDFAAAWMNLGIVQNSLKRFEEAEQSYRTAIKHRRK 613
Cdd:pfam13424   5 ALNNLAAVLRRLGRYDEALELLEKALEIArrllgpdhPLTATTLLNLGRLYLELGRYEEALELLERALALAEK 77
3a0801s09 TIGR00990
mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) ...
 530-767 4.31e-06

mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70); [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273380 [Multi-domain]  Cd Length: 615  Bit Score: 50.37  E-value: 4.31e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564387696  530 TAAIKYYREAVRLN---PKYVHAMNNLGNILKERNELQEAEELLSLAVQIQPDFAAAWMNLGIVQNSLKRFEEAEQSYRT 606
Cdd:TIGR00990 311 EEAARAFEKALDLGklgEKEAIALNLRGTFKCLKGKHLEALADLSKSIELDPRVTQSYIKRASMNLELGDPDKAEEDFDK 390

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564387696  607 AIKHRRKYPDCYYNLGRLYADLNRHVDALNAWRNATVMKPEHSLAWNNMVILLDNTGNLAQAEAVGREALQLIP------ 680
Cdd:TIGR00990 391 ALKLNSEDPDIYYHRAQLHFIKGEFAQAGKDYQKSIDLDPDFIFSHIQLGVTQYKEGSIASSMATFRRCKKNFPeapdvy 470

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564387696  681 ----------NDHS------------------LMFSLANVLGKS-------QKYKESEALFLKAIKANPNVASYHGNLAV 725
Cdd:TIGR00990 471 nyygellldqNKFDeaiekfdtaieleketkpMYMNVLPLINKAlalfqwkQDFIEAENLCEKALIIDPECDIAVATMAQ 550

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 564387696  726 LYHRWGHLDSAKKHYEISLQL----------------DPVAVGTKENYSLLRRKLEQM 767
Cdd:TIGR00990 551 LLLQQGDVDEALKLFERAAELartegelvqaisyaeaTRTQIQVQEDYPVLASKLQGM 608
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 684-748 4.40e-06

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 46.72  E-value: 4.40e-06
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 564387696 684 SLMFSLANVLGKSQKYKESEALFLKAIKANPNVASYHGNLAVLYHRWGHLDSAKKHYEISLQLDP 748
Cdd:COG4783    5 EALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDP 69
TPR_12 pfam13424
Tetratricopeptide repeat;
579-637 4.70e-06

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 45.07  E-value: 4.70e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 564387696  579 DFAAAWMNLGIVQNSLKRFEEAEQSYRTAIKHRRKYPD--------CYYNLGRLYADLNRHVDALNA 637
Cdd:pfam13424   1 DVATALNNLAAVLRRLGRYDEALELLEKALEIARRLLGpdhpltatTLLNLGRLYLELGRYEEALEL 67
TPR_12 pfam13424
Tetratricopeptide repeat;
513-579 6.37e-06

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 44.69  E-value: 6.37e-06
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 564387696  513 AKVHYNIGKNLADQGNQTAAIKYYREAVRL--------NPKYVHAMNNLGNILKERNELQEAEELLSLAVQIQPD 579
Cdd:pfam13424   3 ATALNNLAAVLRRLGRYDEALELLEKALEIarrllgpdHPLTATTLLNLGRLYLELGRYEEALELLERALALAEK 77
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 595-681 1.05e-05

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 44.98  E-value: 1.05e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564387696 595 KRFEEAEQSYRTAIKhrrKYPD------CYYNLGRLYADLNRHVDALNAWRNATVMKPEHSLAWNNMVIL---LDNTGNL 665
Cdd:COG1729    7 GDYDEAIAAFKAFLK---RYPNsplapdALYWLGEAYYALGDYDEAAEAFEKLLKRYPDSPKAPDALLKLglsYLELGDY 83

                         90
                 ....*....|....*.
gi 564387696 666 AQAEAVGREALQLIPN 681
Cdd:COG1729   84 DKARATLEELIKKYPD 99
C39_PA2778_fam NF033920
PA2778 family cysteine peptidase; Members of this family are MEROPS classification C39 family ...
 659-748 1.96e-05

PA2778 family cysteine peptidase; Members of this family are MEROPS classification C39 family cysteine peptidases, a group that includes many processing enzyme for peptide natural products such as lantibiotics and other bacteriocins. This family, more specifically, includes PA2778 as found in Pseudomonas aeruginosa. All members of the defining seed alignment are encoded in the vicinity of a homolog of PA2779 (see HMM NF033919). Note that the C-terminal region consists largely of tetratricopeptide repeats (TPR), so classification using this HMM must be based on comparing the top domain score to the second gathering threshold (GA2).


Pssm-ID: 468245 [Multi-domain]  Cd Length: 255  Bit Score: 46.77  E-value: 1.96e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564387696 659 LDNTGNLAQAEAVGREALQLIPNDHSLMFSLANVLGKSQKYKESEALFLKAIKANPNVASYHGNLAVLYHRWGHLDSAKK 738
Cdd:NF033920 166 LEQTGQPEAALAAYQTATKRWPDSWLAYFGLGNAAYAAGDYAAAAAAFRQAVERHPDSAAAWNNLAYALAAQGCTAQARA 245

                         90
                 ....*....|
gi 564387696 739 HYEISLQLDP 748
Cdd:NF033920 246 AAECALALAP 255
TPR_1 pfam00515
Tetratricopeptide repeat;
513-546 2.52e-05

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 41.64  E-value: 2.52e-05
                          10        20        30
                  ....*....|....*....|....*....|....
gi 564387696  513 AKVHYNIGKNLADQGNQTAAIKYYREAVRLNPKY 546
Cdd:pfam00515   1 AKALYNLGNAYFKLGKYDEALEYYEKALELNPNN 34
ycf3 CHL00033
photosystem I assembly protein Ycf3
 517-573 2.58e-05

photosystem I assembly protein Ycf3


Pssm-ID: 176974 [Multi-domain]  Cd Length: 168  Bit Score: 45.38  E-value: 2.58e-05
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 564387696 517 YNIGKNLADQGNQTAAIKYYREAVRLNPKYVHAMNNL-------GNILKERNELQEAEELLSLA 573
Cdd:CHL00033  76 YNIGLIHTSNGEHTKALEYYFQALERNPFLPQALNNMavichyrGEQAIEQGDSEIAEAWFDQA 139
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 472-546 3.89e-05

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 44.03  E-value: 3.89e-05
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 564387696 472 PVAAIILGILLInalrcviRSGEWRSEDRLFRSALSVCPLNAKVHYNIGKNLADQGNQTAAIKYYREAVRLNPKY 546
Cdd:COG4783   72 PEARLNLGLALL-------KAGDYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALELDPDD 139
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 463-705 3.99e-05

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 47.39  E-value: 3.99e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564387696  463 LSRHTKKKKPVAAIILGILLINALRcvirSGEWRSEDRLFRSALSVCPLNAKVhYNIGKNLADQGNQTAAIKYYREAVRL 542
Cdd:TIGR02917 691 IAKSLQKQHPKAALGFELEGDLYLR----QKDYPAAIQAYRKALKRAPSSQNA-IKLHRALLASGNTAEAVKTLEAWLKT 765

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564387696  543 NPKYVHAMNNLGNILKERNELQEAEELLSLAVQIQPDFAAAWMNLGIVQNSLKR---FEEAEQSYRTAikhrrkyPDcyy 619
Cdd:TIGR02917 766 HPNDAVLRTALAELYLAQKDYDKAIKHYQTVVKKAPDNAVVLNNLAWLYLELKDpraLEYAERALKLA-------PN--- 835

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564387696  620 nlgrlyadlnrhvdalnawrNATVMKpehSLAWnnmviLLDNTGNLAQAEAVGREALQLIPNDHSLMFSLANVLGKSQKY 699
Cdd:TIGR02917 836 --------------------IPAILD---TLGW-----LLVEKGEADRALPLLRKAVNIAPEAAAIRYHLALALLATGRK 887


                  ....*.
gi 564387696  700 KESEAL 705
Cdd:TIGR02917 888 AEARKE 893
TPR_1 pfam00515
Tetratricopeptide repeat;
581-614 5.02e-05

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 40.87  E-value: 5.02e-05
                          10        20        30
                  ....*....|....*....|....*....|....
gi 564387696  581 AAAWMNLGIVQNSLKRFEEAEQSYRTAIKHRRKY 614
Cdd:pfam00515   1 AKALYNLGNAYFKLGKYDEALEYYEKALELNPNN 34
TPR_2 pfam07719
Tetratricopeptide repeat; This Pfam entry includes outlying Tetratricopeptide-like repeats ...
 513-545 5.75e-05

Tetratricopeptide repeat; This Pfam entry includes outlying Tetratricopeptide-like repeats (TPR) that are not matched by pfam00515.


Pssm-ID: 429619 [Multi-domain]  Cd Length: 33  Bit Score: 40.58  E-value: 5.75e-05
                          10        20        30
                  ....*....|....*....|....*....|...
gi 564387696  513 AKVHYNIGKNLADQGNQTAAIKYYREAVRLNPK 545
Cdd:pfam07719   1 AEALYNLGLAYYKLGDYEEALEAYEKALELDPN 33
TPR_12 pfam13424
Tetratricopeptide repeat;
689-746 9.42e-05

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 41.22  E-value: 9.42e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 564387696  689 LANVLGKSQKYKESEALFLKAIKA--------NPNVASYHGNLAVLYHRWGHLDSAKKHYEISLQL 746
Cdd:pfam13424   9 LAAVLRRLGRYDEALELLEKALEIarrllgpdHPLTATTLLNLGRLYLELGRYEEALELLERALAL 74
TPR_11 pfam13414
TPR repeat;
520-559 1.42e-04

TPR repeat;


Pssm-ID: 315977 [Multi-domain]  Cd Length: 42  Bit Score: 39.76  E-value: 1.42e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|
gi 564387696  520 GKNLADQGNQTAAIKYYREAVRLNPKYVHAMNNLGNILKE 559
Cdd:pfam13414   1 GDAYYEQGKYEEAIEAYKKALKLDPDNPEAYYNLGLAYYK 40
TPR_8 pfam13181
Tetratricopeptide repeat;
513-545 1.58e-04

Tetratricopeptide repeat;


Pssm-ID: 404131 [Multi-domain]  Cd Length: 33  Bit Score: 39.30  E-value: 1.58e-04
                          10        20        30
                  ....*....|....*....|....*....|...
gi 564387696  513 AKVHYNIGKNLADQGNQTAAIKYYREAVRLNPK 545
Cdd:pfam13181   1 AEAYYNLGLIYLKLGDYEEAKEYYEKALELDPD 33
TPR_17 pfam13431
Tetratricopeptide repeat;
535-568 2.28e-04

Tetratricopeptide repeat;


Pssm-ID: 433201 [Multi-domain]  Cd Length: 34  Bit Score: 39.06  E-value: 2.28e-04
                          10        20        30
                  ....*....|....*....|....*....|....
gi 564387696  535 YYREAVRLNPKYVHAMNNLGNILKERNELQEAEE 568
Cdd:pfam13431   1 LYLKALELDPNNADAYYNLAVLLLELGQSETALQ 34
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 581-614 2.40e-04

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 38.97  E-value: 2.40e-04
                           10        20        30
                   ....*....|....*....|....*....|....
gi 564387696   581 AAAWMNLGIVQNSLKRFEEAEQSYRTAIKHRRKY 614
Cdd:smart00028   1 AEALYNLGNAYLKLGDYDEALEYYEKALELDPNN 34
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 513-546 2.97e-04

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 38.58  E-value: 2.97e-04
                           10        20        30
                   ....*....|....*....|....*....|....
gi 564387696   513 AKVHYNIGKNLADQGNQTAAIKYYREAVRLNPKY 546
Cdd:smart00028   1 AEALYNLGNAYLKLGDYDEALEYYEKALELDPNN 34
TPR COG0790
TPR repeat [General function prediction only];
513-627 4.02e-04

TPR repeat [General function prediction only];


Pssm-ID: 440553 [Multi-domain]  Cd Length: 241  Bit Score: 42.61  E-value: 4.02e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564387696 513 AKVHYNIGKNLAD----QGNQTAAIKYYREAVRLNpkYVHAMNNLGNILK-----ERNeLQEAEELLSLAVQiQPDFAAA 583
Cdd:COG0790   63 AEAQYNLGLMYAEgrgvPKDYEKALEWFEKAAEQG--DAEAQYNLGLMYEeglgvPQD-YAKALEWYEKAAE-QGDADAQ 138

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*...
gi 564387696 584 WmNLGIV----QNSLKRFEEAEQSYRTAIKhrRKYPDCYYNLGRLYAD 627
Cdd:COG0790  139 Y-NLGLLylngEGVPKDPAKAAEWYRKAAE--QGDADAQYNLGVLYEN 183
TPR COG0790
TPR repeat [General function prediction only];
528-627 4.65e-04

TPR repeat [General function prediction only];


Pssm-ID: 440553 [Multi-domain]  Cd Length: 241  Bit Score: 42.61  E-value: 4.65e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564387696 528 NQTAAIKYYREAVRLNpkYVHAMNNLGNILK-----ERNElQEAEELLSLAVQiQpDFAAAWMNLGIV----QNSLKRFE 598
Cdd:COG0790  118 DYAKALEWYEKAAEQG--DADAQYNLGLLYLngegvPKDP-AKAAEWYRKAAE-Q-GDADAQYNLGVLyengRGVPKDPA 192

                         90       100
                 ....*....|....*....|....*....
gi 564387696 599 EAEQSYRTAIKhrRKYPDCYYNLGRLYAD 627
Cdd:COG0790  193 KALEWYRKAAE--QGDADAQYNLGRLYLN 219
TPR_19 pfam14559
Tetratricopeptide repeat;
561-624 5.50e-04

Tetratricopeptide repeat;


Pssm-ID: 434038 [Multi-domain]  Cd Length: 65  Bit Score: 38.72  E-value: 5.50e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 564387696  561 NELQEAEELLSLAVQIQPDFAAAWMNLGIVQNSLKRFEEAEQSYRTAIKHRRKYPDCYYNLGRL 624
Cdd:pfam14559   2 GDYAEALELLEQALAEDPDNAEARLGLAEALLALGRLDEAEALLAALPAADPDDPRYAALLAKL 65
TPR_19 pfam14559
Tetratricopeptide repeat;
663-726 5.60e-04

Tetratricopeptide repeat;


Pssm-ID: 434038 [Multi-domain]  Cd Length: 65  Bit Score: 38.72  E-value: 5.60e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 564387696  663 GNLAQAEAVGREALQLIPNDHSLMFSLANVLGKSQKYKESEALFLKAIKANPNVASYHGNLAVL 726
Cdd:pfam14559   2 GDYAEALELLEQALAEDPDNAEARLGLAEALLALGRLDEAEALLAALPAADPDDPRYAALLAKL 65
TPR_11 pfam13414
TPR repeat;
593-628 6.02e-04

TPR repeat;


Pssm-ID: 315977 [Multi-domain]  Cd Length: 42  Bit Score: 37.84  E-value: 6.02e-04
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 564387696  593 SLKRFEEAEQSYRTAIKHRRKYPDCYYNLGRLYADL 628
Cdd:pfam13414   6 EQGKYEEAIEAYKKALKLDPDNPEAYYNLGLAYYKL 41
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 661-741 6.21e-04

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 39.97  E-value: 6.21e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564387696 661 NTGNLAQAEAVGREALQLIPNDH---SLMFSLANVLGKSQKYKESEALFLKAIKANPN---VASYHGNLAVLYHRWGHLD 734
Cdd:COG1729    5 KAGDYDEAIAAFKAFLKRYPNSPlapDALYWLGEAYYALGDYDEAAEAFEKLLKRYPDspkAPDALLKLGLSYLELGDYD 84


                 ....*..
gi 564387696 735 SAKKHYE 741
Cdd:COG1729   85 KARATLE 91
TPR_16 pfam13432
Tetratricopeptide repeat; This family is found predominantly at the C-terminus of ...
 619-682 8.98e-04

Tetratricopeptide repeat; This family is found predominantly at the C-terminus of transglutaminase enzyme core regions.


Pssm-ID: 433202 [Multi-domain]  Cd Length: 68  Bit Score: 38.47  E-value: 8.98e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 564387696  619 YNLGRLYADLNRHVDALNAWRNATVM---KPEHSLAWNNMVILLDNTGNLAQAEAVGREALQLIPND 682
Cdd:pfam13432   1 LALARAALRAGDYDDAAAALEAALARfpeSPDAAAALLLLGLAALRQGRLAEAAAAYRAALRAAPGD 67
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 490-545 1.34e-03

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 39.60  E-value: 1.34e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 564387696 490 IRSGEWRSEDRLFRSALSVCPLNAKVHYNIGKNLADQGNQTAAIKYYREAVRLNPK 545
Cdd:COG4235   62 LAAGDTEEAEELLERALALDPDNPEALYLLGLAAFQQGDYAEAIAAWQKLLALLPA 117
TPR_17 pfam13431
Tetratricopeptide repeat;
705-738 1.49e-03

Tetratricopeptide repeat;


Pssm-ID: 433201 [Multi-domain]  Cd Length: 34  Bit Score: 36.75  E-value: 1.49e-03
                          10        20        30
                  ....*....|....*....|....*....|....
gi 564387696  705 LFLKAIKANPNVASYHGNLAVLYHRWGHLDSAKK 738
Cdd:pfam13431   1 LYLKALELDPNNADAYYNLAVLLLELGQSETALQ 34
TPR_11 pfam13414
TPR repeat;
554-591 1.66e-03

TPR repeat;


Pssm-ID: 315977 [Multi-domain]  Cd Length: 42  Bit Score: 36.68  E-value: 1.66e-03
                          10        20        30
                  ....*....|....*....|....*....|....*...
gi 564387696  554 GNILKERNELQEAEELLSLAVQIQPDFAAAWMNLGIVQ 591
Cdd:pfam13414   1 GDAYYEQGKYEEAIEAYKKALKLDPDNPEAYYNLGLAY 38
TPR_10 pfam13374
Tetratricopeptide repeat;
549-577 2.82e-03

Tetratricopeptide repeat;


Pssm-ID: 463861 [Multi-domain]  Cd Length: 42  Bit Score: 35.94  E-value: 2.82e-03
                          10        20
                  ....*....|....*....|....*....
gi 564387696  549 AMNNLGNILKERNELQEAEELLSLAVQIQ 577
Cdd:pfam13374   4 SLNNLANALRAQGRYDEAEELLEEALAIR 32
TPR_16 pfam13432
Tetratricopeptide repeat; This family is found predominantly at the C-terminus of ...
 596-635 6.43e-03

Tetratricopeptide repeat; This family is found predominantly at the C-terminus of transglutaminase enzyme core regions.


Pssm-ID: 433202 [Multi-domain]  Cd Length: 68  Bit Score: 35.77  E-value: 6.43e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|...
gi 564387696  596 RFEEAEQSYRTAIKHRRKYPDC---YYNLGRLYADLNRHVDAL 635
Cdd:pfam13432  12 DYDDAAAALEAALARFPESPDAaaaLLLLGLAALRQGRLAEAA 54
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 717-748 7.42e-03

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 34.73  E-value: 7.42e-03
                           10        20        30
                   ....*....|....*....|....*....|..
gi 564387696   717 ASYHGNLAVLYHRWGHLDSAKKHYEISLQLDP 748
Cdd:smart00028   1 AEALYNLGNAYLKLGDYDEALEYYEKALELDP 32
COG4700 COG4700
Uncharacterized conserved protein ECs_4300, contains TPR-like domain [Function unknown];
523-634 8.67e-03

Uncharacterized conserved protein ECs_4300, contains TPR-like domain [Function unknown];


Pssm-ID: 443735 [Multi-domain]  Cd Length: 249  Bit Score: 38.71  E-value: 8.67e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564387696 523 LADQGNQTAAIKYYREAV-RLNPKYVHAMNNLGNILKERNELQEAEELLSLAVQIQPDF--AAAWMNLGIVQNSLKRFEE 599
Cdd:COG4700   99 LLELGRYDEAIELYEEALtGIFADDPHILLGLAQALFELGRYAEALETLEKLIAKNPDFksSDAHLLYARALEALGDLEA 178

                         90       100       110
                 ....*....|....*....|....*....|....*
gi 564387696 600 AEQSYRTAIKHRRKYPDcYYNLGRLYADLNRHVDA 634
Cdd:COG4700  179 AEAELEALARRYSGPEA-RYRYAKFLARQGRTAEA 212
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 615-648 9.97e-03

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 34.34  E-value: 9.97e-03
                           10        20        30
                   ....*....|....*....|....*....|....
gi 564387696   615 PDCYYNLGRLYADLNRHVDALNAWRNATVMKPEH 648
Cdd:smart00028   1 AEALYNLGNAYLKLGDYDEALEYYEKALELDPNN 34
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH