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Conserved domains on  [gi|672040420|ref|XP_008758646|]
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pyridine nucleotide-disulfide oxidoreductase domain-containing protein 2 isoform X1 [Rattus norvegicus]

Protein Classification

phytoene desaturase family protein( domain architecture ID 11440907)

phytoene desaturase family protein is an NAD(P)/FAD-dependent oxidoreductase that catalyzes the transfer of electrons from one molecule, the electron donor or reductant, to another molecule, the electron acceptor or oxidant; similar to phytoene desaturase, which converts phytoene into 3,4-didehydrolycopene via several intermediates by introducing up to five double bonds into phytoene

CATH:  3.50.50.60
EC:  1.-.-.-
Gene Ontology:  GO:0016491|GO:0009055|GO:0016117|GO:0016116
SCOP:  4000128|3000055

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
COG1233 COG1233
Phytoene dehydrogenase-related protein [Secondary metabolites biosynthesis, transport and ...
 35-559 8.77e-120

Phytoene dehydrogenase-related protein [Secondary metabolites biosynthesis, transport and catabolism];


:

Pssm-ID: 440846 [Multi-domain]  Cd Length: 491  Bit Score: 366.48  E-value: 8.77e-120
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672040420  35 YDAVVIGAGHNGLVAAAYLQRLGVNTAVFERRHVIGGAAVTEEIiPGFKFSRASYLLSLLRP--QIYTDLELKKHgLKLH 112
Cdd:COG1233    4 YDVVVIGAGIGGLAAAALLARAGYRVTVLEKNDTPGGRARTFER-PGFRFDVGPSVLTMPGVleRLFRELGLEDY-LELV 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672040420 113 LRNPySFTPMLEEGtlskppRSLLLGTDVAENQKQISQFSRKDAQAFPRYEEFMKRLVLAIDPLLDAAPvdiaalqhgsl 192
Cdd:COG1233   82 PLDP-AYRVPFPDG------RALDLPRDLERTAAELERLFPGDAEAYRRFLAELRRLYDALLEDLLYRP----------- 143

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672040420 193 lqrlraLSTLRPLLKAgrtlgAQLPQYYEVLTAPISKVLDQWFESEPLKATLATdavIGAMTSPHTPGSGYVLlhHVMGS 272
Cdd:COG1233  144 ------LLSLRDLLRP-----LALARLLRLLLRSLRDLLRRYFKDPRLRALLAG---QALYLGLSPDRTPALY--ALIAY 207

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672040420 273 LEGMQGAWsYVQGGMGALSDAIASSATAHGASIFTEKTVAKVQVnSEGRVQGVVLQGGEEVRSRVVLSCASPQVTFLELT 352
Cdd:COG1233  208 LEYAGGVW-YPKGGMGALADALARLAEELGGEIRTGAEVERILV-EGGRATGVRLADGEEIRADAVVSNADPAHTYLRLL 285

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672040420 353 PQEWLPGAFVKRISQLDTQSPVTKINVAVDR-LPNFqaapnapgdqpqAHHQcsIHLNcEDtllLHQAFEDAKGGLPSQR 431
Cdd:COG1233  286 GEEALPARYRRRLERFRYSPSAFKLYLGLDGpLPGL------------AHHT--IHLS-ED---YEAAFDDIFRGRLPED 347

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672040420 432 PMIELCIPSSLDPTLAPTGCHVVSLFTQyTPYTLagGKVWDEQKKnTYADKVFDCIEAYAPGFKRSVLGRDILTPQDLER 511
Cdd:COG1233  348 PSLYVSIPSLTDPSLAPEGKHTLWVLVP-VPYGL--EDAWDELKE-EYAERILARLERYAPGLRDRIVAREVLTPLDFER 423

                        490       500       510       520
                 ....*....|....*....|....*....|....*....|....*...
gi 672040420 512 IFGLPGGNIFHGAMSLDQLYFARPvpqhSDYRCPVQGLYLCGSGAHPG 559
Cdd:COG1233  424 YLNLVGGAIYGGAHTLDQSAFFRP----SNYRTPIPGLYLVGASTHPG 467
FAD_binding_2 super family cl46878
FAD binding domain; This family includes members that bind FAD. This family includes the ...
 5-61 3.78e-03

FAD binding domain; This family includes members that bind FAD. This family includes the flavoprotein subunits from succinate and fumarate dehydrogenase, aspartate oxidase and the alpha subunit of adenylylsulphate reductase.


The actual alignment was detected with superfamily member PTZ00139:

Pssm-ID: 481218 [Multi-domain]  Cd Length: 617  Bit Score: 40.49  E-value: 3.78e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 672040420   5 GRGLSRALHSTPCPAwKRVQSGANGCLKPEYDAVVIGAGHNGLVAAAYLQRLGVNTA 61
Cdd:PTZ00139   1 RFAVPAFNRLTRTFF-SGHLSSAYPVIDHTYDAVVVGAGGAGLRAALGLVELGYKTA 56
 
Name Accession Description Interval E-value
COG1233 COG1233
Phytoene dehydrogenase-related protein [Secondary metabolites biosynthesis, transport and ...
 35-559 8.77e-120

Phytoene dehydrogenase-related protein [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 440846 [Multi-domain]  Cd Length: 491  Bit Score: 366.48  E-value: 8.77e-120
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672040420  35 YDAVVIGAGHNGLVAAAYLQRLGVNTAVFERRHVIGGAAVTEEIiPGFKFSRASYLLSLLRP--QIYTDLELKKHgLKLH 112
Cdd:COG1233    4 YDVVVIGAGIGGLAAAALLARAGYRVTVLEKNDTPGGRARTFER-PGFRFDVGPSVLTMPGVleRLFRELGLEDY-LELV 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672040420 113 LRNPySFTPMLEEGtlskppRSLLLGTDVAENQKQISQFSRKDAQAFPRYEEFMKRLVLAIDPLLDAAPvdiaalqhgsl 192
Cdd:COG1233   82 PLDP-AYRVPFPDG------RALDLPRDLERTAAELERLFPGDAEAYRRFLAELRRLYDALLEDLLYRP----------- 143

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672040420 193 lqrlraLSTLRPLLKAgrtlgAQLPQYYEVLTAPISKVLDQWFESEPLKATLATdavIGAMTSPHTPGSGYVLlhHVMGS 272
Cdd:COG1233  144 ------LLSLRDLLRP-----LALARLLRLLLRSLRDLLRRYFKDPRLRALLAG---QALYLGLSPDRTPALY--ALIAY 207

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672040420 273 LEGMQGAWsYVQGGMGALSDAIASSATAHGASIFTEKTVAKVQVnSEGRVQGVVLQGGEEVRSRVVLSCASPQVTFLELT 352
Cdd:COG1233  208 LEYAGGVW-YPKGGMGALADALARLAEELGGEIRTGAEVERILV-EGGRATGVRLADGEEIRADAVVSNADPAHTYLRLL 285

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672040420 353 PQEWLPGAFVKRISQLDTQSPVTKINVAVDR-LPNFqaapnapgdqpqAHHQcsIHLNcEDtllLHQAFEDAKGGLPSQR 431
Cdd:COG1233  286 GEEALPARYRRRLERFRYSPSAFKLYLGLDGpLPGL------------AHHT--IHLS-ED---YEAAFDDIFRGRLPED 347

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672040420 432 PMIELCIPSSLDPTLAPTGCHVVSLFTQyTPYTLagGKVWDEQKKnTYADKVFDCIEAYAPGFKRSVLGRDILTPQDLER 511
Cdd:COG1233  348 PSLYVSIPSLTDPSLAPEGKHTLWVLVP-VPYGL--EDAWDELKE-EYAERILARLERYAPGLRDRIVAREVLTPLDFER 423

                        490       500       510       520
                 ....*....|....*....|....*....|....*....|....*...
gi 672040420 512 IFGLPGGNIFHGAMSLDQLYFARPvpqhSDYRCPVQGLYLCGSGAHPG 559
Cdd:COG1233  424 YLNLVGGAIYGGAHTLDQSAFFRP----SNYRTPIPGLYLVGASTHPG 467
crtI_fam TIGR02734
phytoene desaturase; Phytoene is converted to lycopene by desaturation at four (two ...
 37-559 2.25e-31

phytoene desaturase; Phytoene is converted to lycopene by desaturation at four (two symmetrical pairs of) sites. This is achieved by two enzymes (crtP and crtQ) in cyanobacteria (Gloeobacter being an exception) and plants, but by a single enzyme in most other bacteria and in fungi. This single enzyme is called the bacterial-type phytoene desaturase, or CrtI. Most members of this family, part of the larger pfam01593, which also contains amino oxidases, are CrtI itself; it is likely that all members act on either phytoene or on related compounds such as dehydrosqualene, for carotenoid biosynthesis. [Biosynthesis of cofactors, prosthetic groups, and carriers, Other]


Pssm-ID: 274273 [Multi-domain]  Cd Length: 495  Bit Score: 128.55  E-value: 2.25e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672040420   37 AVVIGAGHNGLVAAAYLQRLGVNTAVFERRHVIGGAAVTEEiIPGFKFSrasyllslLRPQIYTDLELKKHGLKL---HL 113
Cdd:TIGR02734   1 AVVIGAGFGGLALAIRLAAAGIPVTVVEQRDKPGGRAGVLE-DDGFRFD--------TGPTVITMPEALEELFALagrDL 71

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672040420  114 RNPYSFTPMLEEGTLSKPP-RSLLLGTDVAENQKQISQFSRKDAQAFPRYEEFMKRLV-LAIDPLLDAAPVDIAALQHGS 191
Cdd:TIGR02734  72 ADYVELVPLDPFYRLCWEDgSQLDVDNDQEELEAQIARFNPGDVAGYRRFLDYAERVYrEGYRKLGYVPFLSPRDLLRAD 151

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672040420  192 LLQRLRalstlrplLKAGRTLGAQLPQYyevltapiskvldqwFESEPLKATLATDAV-IGamTSPHTPGSGYVLLHHvm 270
Cdd:TIGR02734 152 APQLLA--------LLAWRSLYSKVARF---------------FSDERLRQAFSFHALfLG--GNPFRTPSIYALISA-- 204

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672040420  271 gsLEGMQGAWsYVQGGMGALSDAIASSATAHGASIFTEKTVAKVQVnSEGRVQGVVLQGGEEVRSRVVLSCASPQVTFLE 350
Cdd:TIGR02734 205 --LEREWGVW-FPRGGTGALVAAMAKLAEDLGGELRLNAEVIRIET-EGGRATAVHLADGERLDADAVVSNADLHHTYRR 280

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672040420  351 LTPQE--------------WLPGAFVKRISQLDTQspvtkinvavdrlpnfqaapnapGDQPQ-AHHqcSIHLNCEDTLL 415
Cdd:TIGR02734 281 LLPNHprrrypaarlsrkrPSPSLFVLYFGLLGVD-----------------------GHWPQlAHH--TLCFGPRYKEL 335

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672040420  416 LHQAFedaKGGLPSQRPMIELCIPSSLDPTLAPTGCHvvSLFTQY-TPYTLAGGKVWDEQKKnTYADKVFDCIEAYA-PG 493
Cdd:TIGR02734 336 FDEIF---RKGRLAEDPSLYLHRPTVTDPSLAPPGCE--SLYVLApVPHLGTADVDWSVEGP-RYRDRILAYLEERAiPG 409

                         490       500       510       520       530       540
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 672040420  494 FKRSVLGRDILTPQDLERIFGLPGGNIFHGAMSLDQLYFARPvpqHSDYRcPVQGLYLCGSGAHPG 559
Cdd:TIGR02734 410 LRDRIVVERTFTPADFRDRYNAWLGSAFSLEHTLTQSAWFRP---HNRDR-KIDNLYLVGAGTHPG 471
Amino_oxidase pfam01593
Flavin containing amine oxidoreductase; This family consists of various amine oxidases, ...
 46-383 1.04e-13

Flavin containing amine oxidoreductase; This family consists of various amine oxidases, including maze polyamine oxidase (PAO)and various flavin containing monoamine oxidases (MAO). The aligned region includes the flavin binding site of these enzymes. The family also contains phytoene dehydrogenases and related enzymes. In vertebrates MAO plays an important role regulating the intracellular levels of amines via there oxidation; these include various neurotransmitters, neurotoxins and trace amines. In lower eukaryotes such as aspergillus and in bacteria the main role of amine oxidases is to provide a source of ammonium. PAOs in plants, bacteria and protozoa oxidase spermidine and spermine to an aminobutyral, diaminopropane and hydrogen peroxide and are involved in the catabolism of polyamines. Other members of this family include tryptophan 2-monooxygenase, putrescine oxidase, corticosteroid binding proteins and antibacterial glycoproteins.


Pssm-ID: 396255 [Multi-domain]  Cd Length: 446  Bit Score: 73.68  E-value: 1.04e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672040420   46 GLVAAAYLQRLGVNTAVFERRHVIGGAAVTEEIiPGFKFSRASYLLSLLRPQIYTdlELKKHGLKLHLRNPYSFTP---M 122
Cdd:pfam01593   3 GLAAARELLRAGHDVTVLEARDRVGGRIRTVRD-DGFLIELGAMWFHGAQPPLLA--LLKELGLEDRLVLPDPAPFytvL 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672040420  123 LEEGTLSKpprslllgTDVAENQKQISQFSRkdaqaFPRYEEFMKRLVLAIDPLLdAAPVDIAALQHGSLLQRLRALSTL 202
Cdd:pfam01593  80 FAGGRRYP--------GDFRRVPAGWEGLLE-----FGRLLSIPEKLRLGLAALA-SDALDEFDLDDFSLAESLLFLGRR 145

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672040420  203 RPLLKAgrtlgaqlpqyyevltapiskVLDQWFESEPLKATLATDAVIGAMTSPHTPGSGYVLLHHVMGSLEGMqgawSY 282
Cdd:pfam01593 146 GPGDVE---------------------VWDRLIDPELFAALPFASGAFAGDPSELSAGLALPLLWALLGEGGSL----LL 200

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672040420  283 VQGGMGALSDAIAssATAHGASIFTEKTVAKVQVNSEGrvQGVVLQGGEEVRSRVVLsCASPQVTFLELTPQEWLPGAFV 362
Cdd:pfam01593 201 PRGGLGALPDALA--AQLLGGDVRLNTRVRSIDREGDG--VTVTLTDGEVIEADAVI-VTVPLGVLKRILFTPPLPPEKA 275

                         330       340
                  ....*....|....*....|.
gi 672040420  363 KRISQLDTQsPVTKINVAVDR 383
Cdd:pfam01593 276 RAIRNLGYG-PVNKVHLEFDR 295
PRK07233 PRK07233
hypothetical protein; Provisional
 38-385 1.80e-07

hypothetical protein; Provisional


Pssm-ID: 235977 [Multi-domain]  Cd Length: 434  Bit Score: 54.12  E-value: 1.80e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672040420  38 VVIGAGHNGLVAAAYLQRLGVNTAVFERRHVIGG-AAVTEeiIPGFK--------FSRASYLLSLLRpqiytdlELkkhG 108
Cdd:PRK07233   3 AIVGGGIAGLAAAYRLAKRGHEVTVFEADDQLGGlAASFE--FGGLPierfyhhiFKSDEALLELLD-------EL---G 70

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672040420 109 L--KLHLRNPYsfTPMLEEGTLSKpprsllLGTdvaenqkqisqfsrkdaqafpryeefmkrlvlaidplldaaPVDIAA 186
Cdd:PRK07233  71 LedKLRWRETK--TGYYVDGKLYP------LGT-----------------------------------------PLELLR 101

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672040420 187 LQHGSLLQRLR-ALSTL--------RPLLKAG------RTLGaqlPQYYEVLTAPI--SKVLDQWfesEPLKAT--LATD 247
Cdd:PRK07233 102 FPHLSLIDKFRlGLLTLlarrikdwRALDKVPaeewlrRWSG---EGVYEVFWEPLleSKFGDYA---DDVSAAwlWSRI 175

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672040420 248 AVIGAmtsphtpgSGYVLLHHVMGslegmqgawsYVQGGMGALSDAIASSATAHGASIFTEKTVAKVQVNsEGRVQGVVL 327
Cdd:PRK07233 176 KRRGN--------RRYSLFGEKLG----------YLEGGFATLIDALAEAIEARGGEIRLGTPVTSVVID-GGGVTGVEV 236

                        330       340       350       360       370       380       390
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 672040420 328 QGGEEVRSRVVlSCASPQVtFLELTPQewLPGAFVKRISQLDTQS----------PVTKI---NVAVDRLP 385
Cdd:PRK07233 237 DGEEEDFDAVI-STAPPPI-LARLVPD--LPADVLARLRRIDYQGvvcmvlklrrPLTDYywlNINDPGAP 303
PTZ00139 PTZ00139
Succinate dehydrogenase [ubiquinone] flavoprotein subunit; Provisional
 5-61 3.78e-03

Succinate dehydrogenase [ubiquinone] flavoprotein subunit; Provisional


Pssm-ID: 240286 [Multi-domain]  Cd Length: 617  Bit Score: 40.49  E-value: 3.78e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 672040420   5 GRGLSRALHSTPCPAwKRVQSGANGCLKPEYDAVVIGAGHNGLVAAAYLQRLGVNTA 61
Cdd:PTZ00139   1 RFAVPAFNRLTRTFF-SGHLSSAYPVIDHTYDAVVVGAGGAGLRAALGLVELGYKTA 56
 
Name Accession Description Interval E-value
COG1233 COG1233
Phytoene dehydrogenase-related protein [Secondary metabolites biosynthesis, transport and ...
 35-559 8.77e-120

Phytoene dehydrogenase-related protein [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 440846 [Multi-domain]  Cd Length: 491  Bit Score: 366.48  E-value: 8.77e-120
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672040420  35 YDAVVIGAGHNGLVAAAYLQRLGVNTAVFERRHVIGGAAVTEEIiPGFKFSRASYLLSLLRP--QIYTDLELKKHgLKLH 112
Cdd:COG1233    4 YDVVVIGAGIGGLAAAALLARAGYRVTVLEKNDTPGGRARTFER-PGFRFDVGPSVLTMPGVleRLFRELGLEDY-LELV 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672040420 113 LRNPySFTPMLEEGtlskppRSLLLGTDVAENQKQISQFSRKDAQAFPRYEEFMKRLVLAIDPLLDAAPvdiaalqhgsl 192
Cdd:COG1233   82 PLDP-AYRVPFPDG------RALDLPRDLERTAAELERLFPGDAEAYRRFLAELRRLYDALLEDLLYRP----------- 143

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672040420 193 lqrlraLSTLRPLLKAgrtlgAQLPQYYEVLTAPISKVLDQWFESEPLKATLATdavIGAMTSPHTPGSGYVLlhHVMGS 272
Cdd:COG1233  144 ------LLSLRDLLRP-----LALARLLRLLLRSLRDLLRRYFKDPRLRALLAG---QALYLGLSPDRTPALY--ALIAY 207

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672040420 273 LEGMQGAWsYVQGGMGALSDAIASSATAHGASIFTEKTVAKVQVnSEGRVQGVVLQGGEEVRSRVVLSCASPQVTFLELT 352
Cdd:COG1233  208 LEYAGGVW-YPKGGMGALADALARLAEELGGEIRTGAEVERILV-EGGRATGVRLADGEEIRADAVVSNADPAHTYLRLL 285

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672040420 353 PQEWLPGAFVKRISQLDTQSPVTKINVAVDR-LPNFqaapnapgdqpqAHHQcsIHLNcEDtllLHQAFEDAKGGLPSQR 431
Cdd:COG1233  286 GEEALPARYRRRLERFRYSPSAFKLYLGLDGpLPGL------------AHHT--IHLS-ED---YEAAFDDIFRGRLPED 347

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672040420 432 PMIELCIPSSLDPTLAPTGCHVVSLFTQyTPYTLagGKVWDEQKKnTYADKVFDCIEAYAPGFKRSVLGRDILTPQDLER 511
Cdd:COG1233  348 PSLYVSIPSLTDPSLAPEGKHTLWVLVP-VPYGL--EDAWDELKE-EYAERILARLERYAPGLRDRIVAREVLTPLDFER 423

                        490       500       510       520
                 ....*....|....*....|....*....|....*....|....*...
gi 672040420 512 IFGLPGGNIFHGAMSLDQLYFARPvpqhSDYRCPVQGLYLCGSGAHPG 559
Cdd:COG1233  424 YLNLVGGAIYGGAHTLDQSAFFRP----SNYRTPIPGLYLVGASTHPG 467
crtI_fam TIGR02734
phytoene desaturase; Phytoene is converted to lycopene by desaturation at four (two ...
 37-559 2.25e-31

phytoene desaturase; Phytoene is converted to lycopene by desaturation at four (two symmetrical pairs of) sites. This is achieved by two enzymes (crtP and crtQ) in cyanobacteria (Gloeobacter being an exception) and plants, but by a single enzyme in most other bacteria and in fungi. This single enzyme is called the bacterial-type phytoene desaturase, or CrtI. Most members of this family, part of the larger pfam01593, which also contains amino oxidases, are CrtI itself; it is likely that all members act on either phytoene or on related compounds such as dehydrosqualene, for carotenoid biosynthesis. [Biosynthesis of cofactors, prosthetic groups, and carriers, Other]


Pssm-ID: 274273 [Multi-domain]  Cd Length: 495  Bit Score: 128.55  E-value: 2.25e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672040420   37 AVVIGAGHNGLVAAAYLQRLGVNTAVFERRHVIGGAAVTEEiIPGFKFSrasyllslLRPQIYTDLELKKHGLKL---HL 113
Cdd:TIGR02734   1 AVVIGAGFGGLALAIRLAAAGIPVTVVEQRDKPGGRAGVLE-DDGFRFD--------TGPTVITMPEALEELFALagrDL 71

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672040420  114 RNPYSFTPMLEEGTLSKPP-RSLLLGTDVAENQKQISQFSRKDAQAFPRYEEFMKRLV-LAIDPLLDAAPVDIAALQHGS 191
Cdd:TIGR02734  72 ADYVELVPLDPFYRLCWEDgSQLDVDNDQEELEAQIARFNPGDVAGYRRFLDYAERVYrEGYRKLGYVPFLSPRDLLRAD 151

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672040420  192 LLQRLRalstlrplLKAGRTLGAQLPQYyevltapiskvldqwFESEPLKATLATDAV-IGamTSPHTPGSGYVLLHHvm 270
Cdd:TIGR02734 152 APQLLA--------LLAWRSLYSKVARF---------------FSDERLRQAFSFHALfLG--GNPFRTPSIYALISA-- 204

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672040420  271 gsLEGMQGAWsYVQGGMGALSDAIASSATAHGASIFTEKTVAKVQVnSEGRVQGVVLQGGEEVRSRVVLSCASPQVTFLE 350
Cdd:TIGR02734 205 --LEREWGVW-FPRGGTGALVAAMAKLAEDLGGELRLNAEVIRIET-EGGRATAVHLADGERLDADAVVSNADLHHTYRR 280

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672040420  351 LTPQE--------------WLPGAFVKRISQLDTQspvtkinvavdrlpnfqaapnapGDQPQ-AHHqcSIHLNCEDTLL 415
Cdd:TIGR02734 281 LLPNHprrrypaarlsrkrPSPSLFVLYFGLLGVD-----------------------GHWPQlAHH--TLCFGPRYKEL 335

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672040420  416 LHQAFedaKGGLPSQRPMIELCIPSSLDPTLAPTGCHvvSLFTQY-TPYTLAGGKVWDEQKKnTYADKVFDCIEAYA-PG 493
Cdd:TIGR02734 336 FDEIF---RKGRLAEDPSLYLHRPTVTDPSLAPPGCE--SLYVLApVPHLGTADVDWSVEGP-RYRDRILAYLEERAiPG 409

                         490       500       510       520       530       540
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 672040420  494 FKRSVLGRDILTPQDLERIFGLPGGNIFHGAMSLDQLYFARPvpqHSDYRcPVQGLYLCGSGAHPG 559
Cdd:TIGR02734 410 LRDRIVVERTFTPADFRDRYNAWLGSAFSLEHTLTQSAWFRP---HNRDR-KIDNLYLVGAGTHPG 471
Amino_oxidase pfam01593
Flavin containing amine oxidoreductase; This family consists of various amine oxidases, ...
 46-383 1.04e-13

Flavin containing amine oxidoreductase; This family consists of various amine oxidases, including maze polyamine oxidase (PAO)and various flavin containing monoamine oxidases (MAO). The aligned region includes the flavin binding site of these enzymes. The family also contains phytoene dehydrogenases and related enzymes. In vertebrates MAO plays an important role regulating the intracellular levels of amines via there oxidation; these include various neurotransmitters, neurotoxins and trace amines. In lower eukaryotes such as aspergillus and in bacteria the main role of amine oxidases is to provide a source of ammonium. PAOs in plants, bacteria and protozoa oxidase spermidine and spermine to an aminobutyral, diaminopropane and hydrogen peroxide and are involved in the catabolism of polyamines. Other members of this family include tryptophan 2-monooxygenase, putrescine oxidase, corticosteroid binding proteins and antibacterial glycoproteins.


Pssm-ID: 396255 [Multi-domain]  Cd Length: 446  Bit Score: 73.68  E-value: 1.04e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672040420   46 GLVAAAYLQRLGVNTAVFERRHVIGGAAVTEEIiPGFKFSRASYLLSLLRPQIYTdlELKKHGLKLHLRNPYSFTP---M 122
Cdd:pfam01593   3 GLAAARELLRAGHDVTVLEARDRVGGRIRTVRD-DGFLIELGAMWFHGAQPPLLA--LLKELGLEDRLVLPDPAPFytvL 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672040420  123 LEEGTLSKpprslllgTDVAENQKQISQFSRkdaqaFPRYEEFMKRLVLAIDPLLdAAPVDIAALQHGSLLQRLRALSTL 202
Cdd:pfam01593  80 FAGGRRYP--------GDFRRVPAGWEGLLE-----FGRLLSIPEKLRLGLAALA-SDALDEFDLDDFSLAESLLFLGRR 145

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672040420  203 RPLLKAgrtlgaqlpqyyevltapiskVLDQWFESEPLKATLATDAVIGAMTSPHTPGSGYVLLHHVMGSLEGMqgawSY 282
Cdd:pfam01593 146 GPGDVE---------------------VWDRLIDPELFAALPFASGAFAGDPSELSAGLALPLLWALLGEGGSL----LL 200

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672040420  283 VQGGMGALSDAIAssATAHGASIFTEKTVAKVQVNSEGrvQGVVLQGGEEVRSRVVLsCASPQVTFLELTPQEWLPGAFV 362
Cdd:pfam01593 201 PRGGLGALPDALA--AQLLGGDVRLNTRVRSIDREGDG--VTVTLTDGEVIEADAVI-VTVPLGVLKRILFTPPLPPEKA 275

                         330       340
                  ....*....|....*....|.
gi 672040420  363 KRISQLDTQsPVTKINVAVDR 383
Cdd:pfam01593 276 RAIRNLGYG-PVNKVHLEFDR 295
NAD_binding_8 pfam13450
NAD(P)-binding Rossmann-like domain;
39-99 4.75e-10

NAD(P)-binding Rossmann-like domain;


Pssm-ID: 433218 [Multi-domain]  Cd Length: 67  Bit Score: 56.00  E-value: 4.75e-10
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 672040420   39 VIGAGHNGLVAAAYLQRLGVNTAVFERRHVIGGAAVTEEiIPGFKFSR-ASYLLSLLRPQIY 99
Cdd:pfam13450   1 IVGAGLAGLVAAALLAKRGFRVLVLEKRDRLGGNAYSYR-VPGYVFDYgAHIFHGSDEPNVR 61
CzcO COG2072
Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD [Inorganic ...
 33-72 2.90e-08

Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD [Inorganic ion transport and metabolism];


Pssm-ID: 441675 [Multi-domain]  Cd Length: 414  Bit Score: 56.41  E-value: 2.90e-08
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|
gi 672040420  33 PEYDAVVIGAGHNGLVAAAYLQRLGVNTAVFERRHVIGGA 72
Cdd:COG2072    5 EHVDVVVIGAGQAGLAAAYHLRRAGIDFVVLEKADDVGGT 44
PRK07233 PRK07233
hypothetical protein; Provisional
 38-385 1.80e-07

hypothetical protein; Provisional


Pssm-ID: 235977 [Multi-domain]  Cd Length: 434  Bit Score: 54.12  E-value: 1.80e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672040420  38 VVIGAGHNGLVAAAYLQRLGVNTAVFERRHVIGG-AAVTEeiIPGFK--------FSRASYLLSLLRpqiytdlELkkhG 108
Cdd:PRK07233   3 AIVGGGIAGLAAAYRLAKRGHEVTVFEADDQLGGlAASFE--FGGLPierfyhhiFKSDEALLELLD-------EL---G 70

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672040420 109 L--KLHLRNPYsfTPMLEEGTLSKpprsllLGTdvaenqkqisqfsrkdaqafpryeefmkrlvlaidplldaaPVDIAA 186
Cdd:PRK07233  71 LedKLRWRETK--TGYYVDGKLYP------LGT-----------------------------------------PLELLR 101

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672040420 187 LQHGSLLQRLR-ALSTL--------RPLLKAG------RTLGaqlPQYYEVLTAPI--SKVLDQWfesEPLKAT--LATD 247
Cdd:PRK07233 102 FPHLSLIDKFRlGLLTLlarrikdwRALDKVPaeewlrRWSG---EGVYEVFWEPLleSKFGDYA---DDVSAAwlWSRI 175

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672040420 248 AVIGAmtsphtpgSGYVLLHHVMGslegmqgawsYVQGGMGALSDAIASSATAHGASIFTEKTVAKVQVNsEGRVQGVVL 327
Cdd:PRK07233 176 KRRGN--------RRYSLFGEKLG----------YLEGGFATLIDALAEAIEARGGEIRLGTPVTSVVID-GGGVTGVEV 236

                        330       340       350       360       370       380       390
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 672040420 328 QGGEEVRSRVVlSCASPQVtFLELTPQewLPGAFVKRISQLDTQS----------PVTKI---NVAVDRLP 385
Cdd:PRK07233 237 DGEEEDFDAVI-STAPPPI-LARLVPD--LPADVLARLRRIDYQGvvcmvlklrrPLTDYywlNINDPGAP 303
HemY COG1232
Protoporphyrinogen oxidase HemY/PPOX [Coenzyme transport and metabolism]; Protoporphyrinogen ...
 35-383 4.54e-07

Protoporphyrinogen oxidase HemY/PPOX [Coenzyme transport and metabolism]; Protoporphyrinogen oxidase HemY/PPOX is part of the Pathway/BioSystem: Heme biosynthesis


Pssm-ID: 440845 [Multi-domain]  Cd Length: 443  Bit Score: 52.91  E-value: 4.54e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672040420  35 YDAVVIGAGHNGLVAAAYLQRLGVNTAVFERRHVIGGAAVTEEiIPGFK--------FSRASYLLSLLRpqiytDLELKK 106
Cdd:COG1232    2 KRVAVIGGGIAGLTAAYRLAKAGHEVTVLEASDRVGGLIRTVE-VDGFRidrgphsfLTRDPEVLELLR-----ELGLGD 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672040420 107 -------------HGLKLHlRNPYSFTPMLEEGTLSkPPRSLLLGTDVAenqkqISQFSRKDAQAFpryEEFMKRLV--- 170
Cdd:COG1232   76 elvwpntrksyiyYGGKLH-PLPQGPLALLRSPLLS-LAGKLRALLELL-----APRRPPGEDESL---AEFVRRRFgre 145

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672040420 171 ---LAIDPLLDA--ApVDIAALQHGSLLQRLRALStlrpllkagrtlgaqlpqyyevltapiskvldqwfeseplkatLA 245
Cdd:COG1232  146 vyeRLVEPLLEGvyA-GDPDELSADWAFPRLKRLE-------------------------------------------LE 181

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672040420 246 TDAVIGAMTSPHTPGSGyvllHHVMGSLEgmqgawsyvqGGMGALSDAIASSATAhgASIFTEKTVAKVQVNSEGRvqGV 325
Cdd:COG1232  182 HGSLIKGALALRKGAKA----GEVFGYLR----------GGLGTLVEALAEALEA--GEIRLGTRVTAIEREGGGW--RV 243

                        330       340       350       360       370
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 672040420 326 VLQGGEEVRSRVVLSCASPQVTfLELTPQewLPGAFVKRISQLDTQSPVTkINVAVDR 383
Cdd:COG1232  244 TTSDGETIEADAVVSATPAPAL-ARLLAP--LPPEVAAALAGIPYASVAV-VALGFDR 297
GltD COG0493
NADPH-dependent glutamate synthase beta chain or related oxidoreductase [Amino acid transport ...
 39-86 1.68e-06

NADPH-dependent glutamate synthase beta chain or related oxidoreductase [Amino acid transport and metabolism, General function prediction only]; NADPH-dependent glutamate synthase beta chain or related oxidoreductase is part of the Pathway/BioSystem: Glutamine biosynthesis


Pssm-ID: 440259 [Multi-domain]  Cd Length: 434  Bit Score: 50.90  E-value: 1.68e-06
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*...
gi 672040420  39 VIGAGHNGLVAAAYLQRLGVNTAVFERRHVIGGaaVTEEIIPGFKFSR 86
Cdd:COG0493  126 VVGSGPAGLAAAYQLARAGHEVTVFEALDKPGG--LLRYGIPEFRLPK 171
TrxB COG0492
Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones];
35-82 2.10e-06

Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440258 [Multi-domain]  Cd Length: 305  Bit Score: 50.12  E-value: 2.10e-06
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|.
gi 672040420  35 YDAVVIGAGHNGLVAAAYLQRLGVNTAVFERRHViGG-AAVTEEI--IPGF 82
Cdd:COG0492    1 YDVVIIGAGPAGLTAAIYAARAGLKTLVIEGGEP-GGqLATTKEIenYPGF 50
PRK11749 PRK11749
dihydropyrimidine dehydrogenase subunit A; Provisional
 39-83 2.33e-06

dihydropyrimidine dehydrogenase subunit A; Provisional


Pssm-ID: 236967 [Multi-domain]  Cd Length: 457  Bit Score: 50.56  E-value: 2.33e-06
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*
gi 672040420  39 VIGAGHNGLVAAAYLQRLGVNTAVFERRHVIGGaaVTEEIIPGFK 83
Cdd:PRK11749 145 VIGAGPAGLTAAHRLARKGYDVTIFEARDKAGG--LLRYGIPEFR 187
YobN COG1231
Monoamine oxidase [Amino acid transport and metabolism];
33-383 3.58e-06

Monoamine oxidase [Amino acid transport and metabolism];


Pssm-ID: 440844 [Multi-domain]  Cd Length: 440  Bit Score: 49.92  E-value: 3.58e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672040420  33 PEYDAVVIGAGHNGLVAAAYLQRLGVNTAVFERRHVIGGAAVTEEI-------------IPGfkfsRASYLLSLLRpqiy 99
Cdd:COG1231    6 RGKDVVIVGAGLAGLAAARELRKAGLDVTVLEARDRVGGRVWTLRFgddglyaelgamrIPP----SHTNLLALAR---- 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672040420 100 tdlelkKHGLKLHLRNPYSftpmleegtlskpPRSLLlgtdvAENQKQISQfsRKDAQAFPRYEEFMKRLVLAIDPLLDA 179
Cdd:COG1231   78 ------ELGLPLEPFPNEN-------------GNALL-----YLGGKRVRA--GEIAADLRGVAELLAKLLRALAAALDP 131

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672040420 180 APVDIAALQHGSLLQrlrALSTLRPLLKAGRTLGAQLPQYYEVLTAPISkvLDQWFEseplkatlatdavigamtsphtp 259
Cdd:COG1231  132 WAHPAAELDRESLAE---WLRRNGASPSARRLLGLLGAGEYGADPDELS--LLDLLR----------------------- 183

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672040420 260 gsgyvllhhvMGSLEGMQGAWSYVQGGMGALSDAIASSAtahGASIFTEKTVAKVqVNSEGRVQgVVLQGGEEVRSRVVL 339
Cdd:COG1231  184 ----------YAASAGGGAQQFRIVGGMDQLPRALAAEL---GDRIRLGAPVTRI-RQDGDGVT-VTTDDGGTVRADAVI 248

                        330       340       350       360
                 ....*....|....*....|....*....|....*....|....*
gi 672040420 340 SCASPQV-TFLELTPQewLPGAFVKRISQLdTQSPVTKINVAVDR 383
Cdd:COG1231  249 VTVPPSVlRRIEFDPP--LPAAKRAAIQRL-PYGAAIKVFLQFDR 290
PRK06370 PRK06370
FAD-containing oxidoreductase;
33-74 4.06e-06

FAD-containing oxidoreductase;


Pssm-ID: 235787 [Multi-domain]  Cd Length: 463  Bit Score: 49.82  E-value: 4.06e-06
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|..
gi 672040420  33 PEYDAVVIGAGHNGLVAAAYLQRLGVNTAVFERRHViGGAAV 74
Cdd:PRK06370   4 QRYDAIVIGAGQAGPPLAARAAGLGMKVALIERGLL-GGTCV 44
gltD PRK12810
glutamate synthase subunit beta; Reviewed
 27-83 6.63e-05

glutamate synthase subunit beta; Reviewed


Pssm-ID: 237213 [Multi-domain]  Cd Length: 471  Bit Score: 45.93  E-value: 6.63e-05
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 672040420  27 ANGCLKPEYDAV-------VIGAGHNGLVAAAYLQRLGVNTAVFERRHVIGGaaVTEEIIPGFK 83
Cdd:PRK12810 129 EEGWVKPDPPVKrtgkkvaVVGSGPAGLAAADQLARAGHKVTVFERADRIGG--LLRYGIPDFK 190
Lpd COG1249
Dihydrolipoamide dehydrogenase (E3) component of pyruvate/2-oxoglutarate dehydrogenase complex ...
 34-80 7.68e-05

Dihydrolipoamide dehydrogenase (E3) component of pyruvate/2-oxoglutarate dehydrogenase complex or glutathione oxidoreductase [Energy production and conversion]; Dihydrolipoamide dehydrogenase (E3) component of pyruvate/2-oxoglutarate dehydrogenase complex or glutathione oxidoreductase is part of the Pathway/BioSystem: Glycine cleavagePyruvate oxidation


Pssm-ID: 440861 [Multi-domain]  Cd Length: 456  Bit Score: 45.85  E-value: 7.68e-05
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*..
gi 672040420  34 EYDAVVIGAGHNGLVAAAYLQRLGVNTAVFERRHViGGAAVTEEIIP 80
Cdd:COG1249    3 DYDLVVIGAGPGGYVAAIRAAQLGLKVALVEKGRL-GGTCLNVGCIP 48
DadA COG0665
Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism];
34-342 8.05e-05

Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism];


Pssm-ID: 440429 [Multi-domain]  Cd Length: 364  Bit Score: 45.28  E-value: 8.05e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672040420  34 EYDAVVIGAGHNGLVAAAYLQRLGVNTAVFERRHVIGGAavteeiipgfkfSRASYllSLLRPQIytdlelkkhglklhl 113
Cdd:COG0665    2 TADVVVIGGGIAGLSTAYHLARRGLDVTVLERGRPGSGA------------SGRNA--GQLRPGL--------------- 52

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672040420 114 rnpysftpmleegtlskpprslllgtdvaenqkqisqfsrkDAQAFPRYEEFMKRLVLAIDPLLDAAPVDIAALQHGSLL 193
Cdd:COG0665   53 -----------------------------------------AALADRALVRLAREALDLWRELAAELGIDCDFRRTGVLY 91

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672040420 194 --QRLRALSTLRPLLKAGRTLGAQlpqyYEVLTApiskvlDQWFESEPLkatLATDAVIGAMtspHTPGSGYVllHHvmg 271
Cdd:COG0665   92 laRTEAELAALRAEAEALRALGLP----VELLDA------AELREREPG---LGSPDYAGGL---YDPDDGHV--DP--- 150

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 672040420 272 slegmqgawsyvqggmGALSDAIASSATAHGASIFTEKTVAKVQVnSEGRVQGVVLQGGeEVRSRVVLSCA 342
Cdd:COG0665  151 ----------------AKLVRALARAARAAGVRIREGTPVTGLER-EGGRVTGVRTERG-TVRADAVVLAA 203
SdhA COG1053
Succinate dehydrogenase/fumarate reductase, flavoprotein subunit [Energy production and ...
 34-74 8.11e-05

Succinate dehydrogenase/fumarate reductase, flavoprotein subunit [Energy production and conversion]; Succinate dehydrogenase/fumarate reductase, flavoprotein subunit is part of the Pathway/BioSystem: TCA cycle


Pssm-ID: 440673 [Multi-domain]  Cd Length: 443  Bit Score: 45.59  E-value: 8.11e-05
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|.
gi 672040420  34 EYDAVVIGAGHNGLVAAAYLQRLGVNTAVFERRHVIGGAAV 74
Cdd:COG1053    3 EYDVVVVGSGGAGLRAALEAAEAGLKVLVLEKVPPRGGHTA 43
PRK12775 PRK12775
putative trifunctional 2-polyprenylphenol hydroxylase/glutamate synthase subunit beta/ferritin ...
 39-86 9.85e-05

putative trifunctional 2-polyprenylphenol hydroxylase/glutamate synthase subunit beta/ferritin domain-containing protein; Provisional


Pssm-ID: 183738 [Multi-domain]  Cd Length: 1006  Bit Score: 45.70  E-value: 9.85e-05
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*...
gi 672040420   39 VIGAGHNGLVAAAYLQRLGVNTAVFERRHVIGGaaVTEEIIPGFKFSR 86
Cdd:PRK12775  435 ICGSGPAGLAAAADLVKYGVDVTVYEALHVVGG--VLQYGIPSFRLPR 480
DAO pfam01266
FAD dependent oxidoreductase; This family includes various FAD dependent oxidoreductases: ...
 36-73 1.57e-04

FAD dependent oxidoreductase; This family includes various FAD dependent oxidoreductases: Glycerol-3-phosphate dehydrogenase EC:1.1.99.5, Sarcosine oxidase beta subunit EC:1.5.3.1, D-alanine oxidase EC:1.4.99.1, D-aspartate oxidase EC:1.4.3.1.


Pssm-ID: 426168 [Multi-domain]  Cd Length: 339  Bit Score: 44.31  E-value: 1.57e-04
                          10        20        30
                  ....*....|....*....|....*....|....*...
gi 672040420   36 DAVVIGAGHNGLVAAAYLQRLGVNTAVFERRHVIGGAA 73
Cdd:pfam01266   1 DVVVIGGGIVGLSTAYELARRGLSVTLLERGDDPGSGA 38
PLN02576 PLN02576
protoporphyrinogen oxidase
 32-71 1.80e-04

protoporphyrinogen oxidase


Pssm-ID: 215314 [Multi-domain]  Cd Length: 496  Bit Score: 44.62  E-value: 1.80e-04
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|.
gi 672040420  32 KPEYDAVVIGAGHNGLVAAAYLQ-RLGVNTAVFERRHVIGG 71
Cdd:PLN02576  10 ASSKDVAVVGAGVSGLAAAYALAsKHGVNVLVTEARDRVGG 50
UbiH COG0654
2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme ...
 33-66 1.98e-04

2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme transport and metabolism, Energy production and conversion]; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases is part of the Pathway/BioSystem: Ubiquinone biosynthesis


Pssm-ID: 440419 [Multi-domain]  Cd Length: 326  Bit Score: 44.16  E-value: 1.98e-04
                         10        20        30
                 ....*....|....*....|....*....|....
gi 672040420  33 PEYDAVVIGAGHNGLVAAAYLQRLGVNTAVFERR 66
Cdd:COG0654    2 MRTDVLIVGGGPAGLALALALARAGIRVTVVERA 35
PRK05249 PRK05249
Si-specific NAD(P)(+) transhydrogenase;
34-74 2.06e-04

Si-specific NAD(P)(+) transhydrogenase;


Pssm-ID: 235373 [Multi-domain]  Cd Length: 461  Bit Score: 44.38  E-value: 2.06e-04
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|.
gi 672040420  34 EYDAVVIGAGHNGLVAAAYLQRLGVNTAVFERRHVIGGAAV 74
Cdd:PRK05249   5 DYDLVVIGSGPAGEGAAMQAAKLGKRVAVIERYRNVGGGCT 45
Thi4 pfam01946
Thi4 family; This family includes Swiss:P32318 a putative thiamine biosynthetic enzyme.
 34-73 4.90e-04

Thi4 family; This family includes Swiss:P32318 a putative thiamine biosynthetic enzyme.


Pssm-ID: 460393  Cd Length: 232  Bit Score: 42.07  E-value: 4.90e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|.
gi 672040420   34 EYDAVVIGAGHNGLVAAAYL-QRLGVNTAVFERRHVIGGAA 73
Cdd:pfam01946  17 ESDVVIVGAGSSGLTAAYYLaKNRGLKVAIIERSVSPGGGA 57
PLN02976 PLN02976
amine oxidase
 38-76 5.42e-04

amine oxidase


Pssm-ID: 215527 [Multi-domain]  Cd Length: 1713  Bit Score: 43.32  E-value: 5.42e-04
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 672040420   38 VVIGAGHNGLVAAAYLQRLGVNTAVFERRHVIGGAAVTE 76
Cdd:PLN02976  697 IVVGAGPAGLTAARHLQRQGFSVTVLEARSRIGGRVYTD 735
PRK10157 PRK10157
putative oxidoreductase FixC; Provisional
 35-82 8.60e-04

putative oxidoreductase FixC; Provisional


Pssm-ID: 182273 [Multi-domain]  Cd Length: 428  Bit Score: 42.21  E-value: 8.60e-04
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 672040420  35 YDAVVIGAGHNGLVAAAYLQRLGVNTAVFERRHVIGGAAVT---------EEIIPGF 82
Cdd:PRK10157   6 FDAIIVGAGLAGSVAALVLAREGAQVLVIERGNSAGAKNVTggrlyahslEHIIPGF 62
PRK10015 PRK10015
oxidoreductase; Provisional
 34-82 1.52e-03

oxidoreductase; Provisional


Pssm-ID: 182194 [Multi-domain]  Cd Length: 429  Bit Score: 41.50  E-value: 1.52e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 672040420  34 EYDAVVIGAGHNGLVAAAYLQRLGVNTAVFER------RHVIGG---AAVTEEIIPGF 82
Cdd:PRK10015   5 KFDAIVVGAGVAGSVAALVMARAGLDVLVIERgdsagcKNMTGGrlyAHTLEAIIPGF 62
PRK07208 PRK07208
hypothetical protein; Provisional
 36-77 2.79e-03

hypothetical protein; Provisional


Pssm-ID: 235967 [Multi-domain]  Cd Length: 479  Bit Score: 40.64  E-value: 2.79e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|..
gi 672040420  36 DAVVIGAGHNGLVAAAYLQRLGVNTAVFERRHVIGGAAVTEE 77
Cdd:PRK07208   6 SVVIIGAGPAGLTAAYELLKRGYPVTVLEADPVVGGISRTVT 47
GIDA pfam01134
Glucose inhibited division protein A;
36-63 2.84e-03

Glucose inhibited division protein A;


Pssm-ID: 250388 [Multi-domain]  Cd Length: 391  Bit Score: 40.61  E-value: 2.84e-03
                          10        20
                  ....*....|....*....|....*...
gi 672040420   36 DAVVIGAGHNGLVAAAYLQRLGVNTAVF 63
Cdd:pfam01134   1 DVIVIGGGHAGCEAALAAARMGAKVLLI 28
PRK06416 PRK06416
dihydrolipoamide dehydrogenase; Reviewed
 34-71 3.11e-03

dihydrolipoamide dehydrogenase; Reviewed


Pssm-ID: 235798 [Multi-domain]  Cd Length: 462  Bit Score: 40.51  E-value: 3.11e-03
                         10        20        30
                 ....*....|....*....|....*....|....*...
gi 672040420  34 EYDAVVIGAGHNGLVAAAYLQRLGVNTAVFERRHvIGG 71
Cdd:PRK06416   4 EYDVIVIGAGPGGYVAAIRAAQLGLKVAIVEKEK-LGG 40
Pyr_redox_2 pfam07992
Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II ...
 35-111 3.39e-03

Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II oxidoreductases and also NADH oxidases and peroxidases. This domain is actually a small NADH binding domain within a larger FAD binding domain.


Pssm-ID: 400379 [Multi-domain]  Cd Length: 301  Bit Score: 39.99  E-value: 3.39e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672040420   35 YDAVVIGAGHNGLVAAAYLQRLGVNTAVFERR-----------HVIGGAAVTEEIIPGFKFSRASYLLSLLRPQIYTDLE 103
Cdd:pfam07992   1 YDVVVIGGGPAGLAAALTLAQLGGKVTLIEDEgtcpyggcvlsKALLGAAEAPEIASLWADLYKRKEEVVKKLNNGIEVL 80


                  ....*...
gi 672040420  104 LKKHGLKL 111
Cdd:pfam07992  81 LGTEVVSI 88
PTZ00139 PTZ00139
Succinate dehydrogenase [ubiquinone] flavoprotein subunit; Provisional
 5-61 3.78e-03

Succinate dehydrogenase [ubiquinone] flavoprotein subunit; Provisional


Pssm-ID: 240286 [Multi-domain]  Cd Length: 617  Bit Score: 40.49  E-value: 3.78e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 672040420   5 GRGLSRALHSTPCPAwKRVQSGANGCLKPEYDAVVIGAGHNGLVAAAYLQRLGVNTA 61
Cdd:PTZ00139   1 RFAVPAFNRLTRTFF-SGHLSSAYPVIDHTYDAVVVGAGGAGLRAALGLVELGYKTA 56
PRK06753 PRK06753
hypothetical protein; Provisional
 39-69 4.11e-03

hypothetical protein; Provisional


Pssm-ID: 168661 [Multi-domain]  Cd Length: 373  Bit Score: 40.06  E-value: 4.11e-03
                         10        20        30
                 ....*....|....*....|....*....|.
gi 672040420  39 VIGAGHNGLVAAAYLQRLGVNTAVFERRHVI 69
Cdd:PRK06753   5 IIGAGIGGLTAAALLQEQGHEVKVFEKNESV 35
PRK12844 PRK12844
3-ketosteroid-delta-1-dehydrogenase; Reviewed
 34-72 5.70e-03

3-ketosteroid-delta-1-dehydrogenase; Reviewed


Pssm-ID: 183787 [Multi-domain]  Cd Length: 557  Bit Score: 39.74  E-value: 5.70e-03
                         10        20        30
                 ....*....|....*....|....*....|....*....
gi 672040420  34 EYDAVVIGAGHNGLVAAAYLQRLGVNTAVFERRHVIGGA 72
Cdd:PRK12844   6 TYDVVVVGSGGGGMCAALAAADSGLEPLIVEKQDKVGGS 44
PRK06292 PRK06292
dihydrolipoamide dehydrogenase; Validated
 34-65 6.72e-03

dihydrolipoamide dehydrogenase; Validated


Pssm-ID: 235774 [Multi-domain]  Cd Length: 460  Bit Score: 39.39  E-value: 6.72e-03
                         10        20        30
                 ....*....|....*....|....*....|..
gi 672040420  34 EYDAVVIGAGHNGLVAAAYLQRLGVNTAVFER 65
Cdd:PRK06292   3 KYDVIVIGAGPAGYVAARRAAKLGKKVALIEK 34
FAD_binding_2 pfam00890
FAD binding domain; This family includes members that bind FAD. This family includes the ...
 36-74 7.23e-03

FAD binding domain; This family includes members that bind FAD. This family includes the flavoprotein subunits from succinate and fumarate dehydrogenase, aspartate oxidase and the alpha subunit of adenylylsulphate reductase.


Pssm-ID: 395718 [Multi-domain]  Cd Length: 398  Bit Score: 39.19  E-value: 7.23e-03
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 672040420   36 DAVVIGAGHNGLVAAAYLQRLGVNTAVFERRHVIGGAAV 74
Cdd:pfam00890   1 DVLVIGGGLAGLAAALAAAEAGLKVAVVEKGQPFGGATA 39
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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