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Conserved domains on  [gi|695077801|ref|XP_009386261|]
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SNF1-related protein kinase regulatory subunit beta-1 [Musa acuminata AAA Group]

Protein Classification

5'-AMP-activated protein kinase beta subunit family protein( domain architecture ID 11244027)

5'-AMP-activated protein kinase beta subunit family protein is a non-catalytic subunit of a protein kinase, such as Arabidopsis thaliana SNF1-related protein kinase regulatory subunit beta-1 and beta-2 which are subunits of the probable trimeric SNF1-related protein kinase (SnRK) complex

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
AMPK1_CBM pfam16561
Glycogen recognition site of AMP-activated protein kinase; AMPK1_CBM is a family found in ...
 93-173 6.67e-42

Glycogen recognition site of AMP-activated protein kinase; AMPK1_CBM is a family found in close association with AMPKBI pfam04739. The surface of AMPK1_CBM reveals a carbohydrate-binding pocket.


:

Pssm-ID: 465176 [Multi-domain]  Cd Length: 85  Bit Score: 138.82  E-value: 6.67e-42
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695077801   93 IATLITWGHGGKEVLVEGSWDNWTSRKALQTSGKDHSILLVLPSGIYHYKFIVDGELRFIPDLPHMAYETGHTVNILDVS 172
Cdd:pfam16561   1 VPTVITWRGGGKKVYVTGSFDNWKKKIPLQKSGGDFTTILDLPPGTHQYKFIVDGEWRHDPDLPTATDDMGNLNNYIEVK 80


                  .
gi 695077801  173 D 173
Cdd:pfam16561  81 A 81
AMPKBI pfam04739
5'-AMP-activated protein kinase beta subunit, interaction domain; This region is found in the ...
 206-273 2.74e-30

5'-AMP-activated protein kinase beta subunit, interaction domain; This region is found in the beta subunit of the 5'-AMP-activated protein kinase complex, and its yeast homologs Sip1, Sip2 and Gal83, which are found in the SNF1 kinase complex. This region is sufficient for interaction of this subunit with the kinase complex, but is not solely responsible for the interaction, and the interaction partner is not known. The isoamylase N-terminal domain (pfam02922) is sometimes found in proteins belonging to this family.


:

Pssm-ID: 461416  Cd Length: 70  Bit Score: 108.39  E-value: 2.74e-30
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 695077801  206 AKEPPMLPPQLHLTVL----GSREAEASSTKPQHVVLNHLFIEKGWasQSLVALGLTHRFQSKYVTVVLYKP 273
Cdd:pfam04739   1 AKEPPALPPHLHLTILnkpsSSSDDPSLLPRPNHVVLNHLYTSSIK--DGVLALGTTHRYKSKYVTTVLYKP 70
 
Name Accession Description Interval E-value
AMPK1_CBM pfam16561
Glycogen recognition site of AMP-activated protein kinase; AMPK1_CBM is a family found in ...
 93-173 6.67e-42

Glycogen recognition site of AMP-activated protein kinase; AMPK1_CBM is a family found in close association with AMPKBI pfam04739. The surface of AMPK1_CBM reveals a carbohydrate-binding pocket.


Pssm-ID: 465176 [Multi-domain]  Cd Length: 85  Bit Score: 138.82  E-value: 6.67e-42
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695077801   93 IATLITWGHGGKEVLVEGSWDNWTSRKALQTSGKDHSILLVLPSGIYHYKFIVDGELRFIPDLPHMAYETGHTVNILDVS 172
Cdd:pfam16561   1 VPTVITWRGGGKKVYVTGSFDNWKKKIPLQKSGGDFTTILDLPPGTHQYKFIVDGEWRHDPDLPTATDDMGNLNNYIEVK 80


                  .
gi 695077801  173 D 173
Cdd:pfam16561  81 A 81
AMPKBI pfam04739
5'-AMP-activated protein kinase beta subunit, interaction domain; This region is found in the ...
 206-273 2.74e-30

5'-AMP-activated protein kinase beta subunit, interaction domain; This region is found in the beta subunit of the 5'-AMP-activated protein kinase complex, and its yeast homologs Sip1, Sip2 and Gal83, which are found in the SNF1 kinase complex. This region is sufficient for interaction of this subunit with the kinase complex, but is not solely responsible for the interaction, and the interaction partner is not known. The isoamylase N-terminal domain (pfam02922) is sometimes found in proteins belonging to this family.


Pssm-ID: 461416  Cd Length: 70  Bit Score: 108.39  E-value: 2.74e-30
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 695077801  206 AKEPPMLPPQLHLTVL----GSREAEASSTKPQHVVLNHLFIEKGWasQSLVALGLTHRFQSKYVTVVLYKP 273
Cdd:pfam04739   1 AKEPPALPPHLHLTILnkpsSSSDDPSLLPRPNHVVLNHLYTSSIK--DGVLALGTTHRYKSKYVTTVLYKP 70
E_set_AMPKbeta_like_N cd02859
N-terminal Early set domain, a glycogen binding domain, associated with the catalytic domain ...
 95-171 1.50e-22

N-terminal Early set domain, a glycogen binding domain, associated with the catalytic domain of AMP-activated protein kinase beta subunit; E or "early" set domains are associated with the catalytic domain of AMP-activated protein kinase beta subunit glycogen binding domain at the N-terminal end. AMPK is a metabolic stress sensing protein that senses AMP/ATP and has recently been found to act as a glycogen sensor as well. The protein functions as an alpha-beta-gamma heterotrimer. This N-terminal domain is the glycogen binding domain of the beta subunit. This domain is also a member of the CBM48 (Carbohydrate Binding Module 48) family whose members include pullulanase, maltooligosyl trehalose synthase, starch branching enzyme, glycogen branching enzyme, glycogen debranching enzyme, and isoamylase.


Pssm-ID: 199889 [Multi-domain]  Cd Length: 80  Bit Score: 88.42  E-value: 1.50e-22
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 695077801  95 TLITW-GHGGKEVLVEGSWDNWTSRKALQTSGK-DHSILLVLPSGIYHYKFIVDGELRFIPDLPHMAYETGHTVNILDV 171
Cdd:cd02859    2 VTFRWpGPGGKEVYVTGSFDNWQQPIPLEKSGDgEFSATVELPPGRYEYKFIVDGEWVHDPDLPTVTDEFGNLNNVLEV 80
AMPKBI smart01010
5'-AMP-activated protein kinase beta subunit, interation domain; This region is found in the ...
 189-274 1.30e-19

5'-AMP-activated protein kinase beta subunit, interation domain; This region is found in the beta subunit of the 5'-AMP-activated protein kinase complex, and its yeast homologues Sip1, Sip2 and Gal83, which are found in the SNF1 kinase complex. This region is sufficient for interaction of this subunit with the kinase complex, but is not solely responsible for the interaction, and the interaction partner is not known. The isoamylase N-terminal domain is sometimes found in proteins belonging to this family.


Pssm-ID: 214973  Cd Length: 100  Bit Score: 81.21  E-value: 1.30e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695077801   189 PSPNSSYGGSFPV-----------DEDYAKEPPMLPPQLHLTVL-----GSREAEASSTKPQHVVLNHLFIEKGwaSQSL 252
Cdd:smart01010   1 QSPPESYTNEIPAcftdddfieesPEEKWKEPPALPPHLEKVILntsstATREDPSLLPIPNHVVLNHLYTSSI--KDGV 78

                           90       100
                   ....*....|....*....|..
gi 695077801   253 VALGLTHRFQSKYVTVVLYKPM 274
Cdd:smart01010  79 LAVAATTRYRGKYVTQVLYKPL 100
 
Name Accession Description Interval E-value
AMPK1_CBM pfam16561
Glycogen recognition site of AMP-activated protein kinase; AMPK1_CBM is a family found in ...
 93-173 6.67e-42

Glycogen recognition site of AMP-activated protein kinase; AMPK1_CBM is a family found in close association with AMPKBI pfam04739. The surface of AMPK1_CBM reveals a carbohydrate-binding pocket.


Pssm-ID: 465176 [Multi-domain]  Cd Length: 85  Bit Score: 138.82  E-value: 6.67e-42
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695077801   93 IATLITWGHGGKEVLVEGSWDNWTSRKALQTSGKDHSILLVLPSGIYHYKFIVDGELRFIPDLPHMAYETGHTVNILDVS 172
Cdd:pfam16561   1 VPTVITWRGGGKKVYVTGSFDNWKKKIPLQKSGGDFTTILDLPPGTHQYKFIVDGEWRHDPDLPTATDDMGNLNNYIEVK 80


                  .
gi 695077801  173 D 173
Cdd:pfam16561  81 A 81
AMPKBI pfam04739
5'-AMP-activated protein kinase beta subunit, interaction domain; This region is found in the ...
 206-273 2.74e-30

5'-AMP-activated protein kinase beta subunit, interaction domain; This region is found in the beta subunit of the 5'-AMP-activated protein kinase complex, and its yeast homologs Sip1, Sip2 and Gal83, which are found in the SNF1 kinase complex. This region is sufficient for interaction of this subunit with the kinase complex, but is not solely responsible for the interaction, and the interaction partner is not known. The isoamylase N-terminal domain (pfam02922) is sometimes found in proteins belonging to this family.


Pssm-ID: 461416  Cd Length: 70  Bit Score: 108.39  E-value: 2.74e-30
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 695077801  206 AKEPPMLPPQLHLTVL----GSREAEASSTKPQHVVLNHLFIEKGWasQSLVALGLTHRFQSKYVTVVLYKP 273
Cdd:pfam04739   1 AKEPPALPPHLHLTILnkpsSSSDDPSLLPRPNHVVLNHLYTSSIK--DGVLALGTTHRYKSKYVTTVLYKP 70
E_set_AMPKbeta_like_N cd02859
N-terminal Early set domain, a glycogen binding domain, associated with the catalytic domain ...
 95-171 1.50e-22

N-terminal Early set domain, a glycogen binding domain, associated with the catalytic domain of AMP-activated protein kinase beta subunit; E or "early" set domains are associated with the catalytic domain of AMP-activated protein kinase beta subunit glycogen binding domain at the N-terminal end. AMPK is a metabolic stress sensing protein that senses AMP/ATP and has recently been found to act as a glycogen sensor as well. The protein functions as an alpha-beta-gamma heterotrimer. This N-terminal domain is the glycogen binding domain of the beta subunit. This domain is also a member of the CBM48 (Carbohydrate Binding Module 48) family whose members include pullulanase, maltooligosyl trehalose synthase, starch branching enzyme, glycogen branching enzyme, glycogen debranching enzyme, and isoamylase.


Pssm-ID: 199889 [Multi-domain]  Cd Length: 80  Bit Score: 88.42  E-value: 1.50e-22
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 695077801  95 TLITW-GHGGKEVLVEGSWDNWTSRKALQTSGK-DHSILLVLPSGIYHYKFIVDGELRFIPDLPHMAYETGHTVNILDV 171
Cdd:cd02859    2 VTFRWpGPGGKEVYVTGSFDNWQQPIPLEKSGDgEFSATVELPPGRYEYKFIVDGEWVHDPDLPTVTDEFGNLNNVLEV 80
AMPKBI smart01010
5'-AMP-activated protein kinase beta subunit, interation domain; This region is found in the ...
 189-274 1.30e-19

5'-AMP-activated protein kinase beta subunit, interation domain; This region is found in the beta subunit of the 5'-AMP-activated protein kinase complex, and its yeast homologues Sip1, Sip2 and Gal83, which are found in the SNF1 kinase complex. This region is sufficient for interaction of this subunit with the kinase complex, but is not solely responsible for the interaction, and the interaction partner is not known. The isoamylase N-terminal domain is sometimes found in proteins belonging to this family.


Pssm-ID: 214973  Cd Length: 100  Bit Score: 81.21  E-value: 1.30e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695077801   189 PSPNSSYGGSFPV-----------DEDYAKEPPMLPPQLHLTVL-----GSREAEASSTKPQHVVLNHLFIEKGwaSQSL 252
Cdd:smart01010   1 QSPPESYTNEIPAcftdddfieesPEEKWKEPPALPPHLEKVILntsstATREDPSLLPIPNHVVLNHLYTSSI--KDGV 78

                           90       100
                   ....*....|....*....|..
gi 695077801   253 VALGLTHRFQSKYVTVVLYKPM 274
Cdd:smart01010  79 LAVAATTRYRGKYVTQVLYKPL 100
E_set_Esterase_like_N cd11294
N-terminal Early set domain associated with the catalytic domain of putative esterases; E or ...
 104-147 5.10e-03

N-terminal Early set domain associated with the catalytic domain of putative esterases; E or "early" set domains are associated with the catalytic domain of esterase at the N-terminal end. Esterases catalyze the hydrolysis of organic esters to release an alcohol or thiol and acid. The term esterase can be applied to enzymes that hydrolyze carboxylate, phosphate and sulphate esters, but is more often restricted to the first class of substrate. The N-terminal domain of esterase may be related to the immunoglobulin and/or fibronectin type III superfamilies. These domains are associated with different types of catalytic domains at either the N-terminal or C-terminal end and may be involved in homodimeric/tetrameric/dodecameric interactions. Members of this family include members of the alpha amylase family, sialidase, galactose oxidase, cellulase, cellulose, hyaluronate lyase, chitobiase, and chitinase, among others.


Pssm-ID: 199894 [Multi-domain]  Cd Length: 83  Bit Score: 35.24  E-value: 5.10e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|...
gi 695077801 104 KEVLVEGSWDNWTSRKALQ---------TSGkdhsillVLPSGIYHYKFIVDG 147
Cdd:cd11294   13 KKVEVTGDFLPGPGPVAMTkdddgvwsvTTG-------PLAPEIYSYSFNVDG 58
E_set_Isoamylase_like_N cd07184
N-terminal Early set domain associated with the catalytic domain of isoamylase-like (also ...
 101-148 8.10e-03

N-terminal Early set domain associated with the catalytic domain of isoamylase-like (also called glycogen 6-glucanohydrolase) proteins; E or "early" set domains are associated with the catalytic domain of isoamylase-like proteins at the N-terminal end. Isoamylase is one of the starch-debranching enzymes that catalyze the hydrolysis of alpha-1,6-glucosidic linkages specific in alpha-glucans such as amylopectin or glycogen. Isoamylase contains a bound calcium ion, but this is not in the same position as the conserved calcium ion that has been reported in other alpha-amylase family enzymes. The N-terminal domain of isoamylase may be related to the immunoglobulin and/or fibronectin type III superfamilies. These domains are associated with different types of catalytic domains at either the N-terminal or C-terminal end and may be involved in homodimeric/tetrameric/dodecameric interactions. Members of this family include members of the alpha amylase family, sialidase, galactose oxidase, cellulase, cellulose, hyaluronate lyase, chitobiase, and chitinase. This domain is also a member of the CBM48 (Carbohydrate Binding Module 48) family whose members include pullulanase, maltooligosyl trehalose synthase, starch branching enzyme, glycogen branching enzyme, glycogen debranching enzyme, and the beta subunit of AMP-activated protein kinase.


Pssm-ID: 199892 [Multi-domain]  Cd Length: 86  Bit Score: 34.91  E-value: 8.10e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|.
gi 695077801 101 HGGKEVLVEGSWDNWTSRKALQTSGKDH--SILLVLPSG-IYHYKFIVDGE 148
Cdd:cd07184   11 QGADSVSLVGDFNDWDPQATPMKKLKNGtfSATLDLPAGrEYQFRYLIDGE 61
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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