|
Name |
Accession |
Description |
Interval |
E-value |
| WD40 |
COG2319 |
WD40 repeat [General function prediction only]; |
3-329 |
6.84e-37 |
|
WD40 repeat [General function prediction only];
Pssm-ID: 441893 [Multi-domain] Cd Length: 403 Bit Score: 142.74 E-value: 6.84e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958674738 3 HILAVANEEGFVRLYNTESQTskktCFKEWMAHWNAVFDLAWVPGELKLVTAAGDQTAKFWDVKAGELMGTCKGHQCSLK 82
Cdd:COG2319 133 KTLASGSADGTVRLWDLATGK----LLRTLTGHSGAVTSVAFSPDGKLLASGSDDGTVRLWDLATGKLLRTLTGHTGAVR 208
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958674738 83 SVAFSKFQKAVFcTGGRDGNIMIWDTrcnkkdgfyrqvnqisgahntadkqtpskpkkkQNSKGLAPSVDSQQSVTVVLF 162
Cdd:COG2319 209 SVAFSPDGKLLA-SGSADGTVRLWDL---------------------------------ATGKLLRTLTGHSGSVRSVAF 254
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958674738 163 -QDENTVVSAGAvDGIIKVWDLRknytayrqepiasksflyPGTSTRKLGY-----SSLVLDSTGSTLFANCTDDNIYMF 236
Cdd:COG2319 255 sPDGRLLASGSA-DGTVRLWDLA------------------TGELLRTLTGhsggvNSVAFSPDGKLLASGSDDGTVRLW 315
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958674738 237 NMTGLKtsPLAVFNGHQNSTFYVksSLSPDDQFLISGSSDEAAYIWKVSmPWHPPTVLLGHSQEVTSVCWCPsDFTKIAT 316
Cdd:COG2319 316 DLATGK--LLRTLTGHTGAVRSV--AFSPDGKTLASGSDDGTVRLWDLA-TGELLRTLTGHTGAVTSVAFSP-DGRTLAS 389
|
330
....*....|...
gi 1958674738 317 CSDDNTLKIWRLN 329
Cdd:COG2319 390 GSADGTVRLWDLA 402
|
|
| WD40 |
cd00200 |
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ... |
3-327 |
1.66e-36 |
|
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.
Pssm-ID: 238121 [Multi-domain] Cd Length: 289 Bit Score: 138.62 E-value: 1.66e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958674738 3 HILAVANEEGFVRLYNTESQTSKKTCfkewMAHWNAVFDLAWVPGELKLVTAAGDQTAKFWDVKAGELMGTCKGHQCSLK 82
Cdd:cd00200 22 KLLATGSGDGTIKVWDLETGELLRTL----KGHTGPVRDVAASADGTYLASGSSDKTIRLWDLETGECVRTLTGHTSYVS 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958674738 83 SVAFSKFQKaVFCTGGRDGNIMIWDTRCNKkdgfyrQVNQISGaHNtadkqtpskpkkkqnskglapsvdsqQSVTVVLF 162
Cdd:cd00200 98 SVAFSPDGR-ILSSSSRDKTIKVWDVETGK------CLTTLRG-HT--------------------------DWVNSVAF 143
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958674738 163 QDENTVVSAGAVDGIIKVWDLRKNYTAYRqepiasksflYPGtstRKLGYSSLVLDSTGSTLFANCTDDNIYMFNMTGLK 242
Cdd:cd00200 144 SPDGTFVASSSQDGTIKLWDLRTGKCVAT----------LTG---HTGEVNSVAFSPDGEKLLSSSSDGTIKLWDLSTGK 210
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958674738 243 TspLAVFNGHQNSTFYVksSLSPDDQFLISGSSDEAAYIWKVsMPWHPPTVLLGHSQEVTSVCWCPsDFTKIATCSDDNT 322
Cdd:cd00200 211 C--LGTLRGHENGVNSV--AFSPDGYLLASGSEDGTIRVWDL-RTGECVQTLSGHTNSVTSLAWSP-DGKRLASGSADGT 284
|
....*
gi 1958674738 323 LKIWR 327
Cdd:cd00200 285 IRIWD 289
|
|
| WD40 |
smart00320 |
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ... |
287-326 |
3.87e-07 |
|
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.
Pssm-ID: 197651 [Multi-domain] Cd Length: 40 Bit Score: 46.92 E-value: 3.87e-07
10 20 30 40
....*....|....*....|....*....|....*....|
gi 1958674738 287 PWHPPTVLLGHSQEVTSVCWCPsDFTKIATCSDDNTLKIW 326
Cdd:smart00320 1 SGELLKTLKGHTGPVTSVAFSP-DGKYLASGSDDGTIKLW 39
|
|
| PLN00181 |
PLN00181 |
protein SPA1-RELATED; Provisional |
169-350 |
9.61e-07 |
|
protein SPA1-RELATED; Provisional
Pssm-ID: 177776 [Multi-domain] Cd Length: 793 Bit Score: 52.01 E-value: 9.61e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958674738 169 VSAGAVDGIIKVWDLRKNYTAYRQEPIASKSFlypgtstrklgysSLVLDSTGSTLFANCTDDNiymfnmtglKTSPLAV 248
Cdd:PLN00181 548 VASSNFEGVVQVWDVARSQLVTEMKEHEKRVW-------------SIDYSSADPTLLASGSDDG---------SVKLWSI 605
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958674738 249 FNGHQNSTFYVKSSLS----PDD--QFLISGSSDEAAYIWKVSMPWHPPTVLLGHSQEVTSVCWCpsDFTKIATCSDDNT 322
Cdd:PLN00181 606 NQGVSIGTIKTKANICcvqfPSEsgRSLAFGSADHKVYYYDLRNPKLPLCTMIGHSKTVSYVRFV--DSSTLVSSSTDNT 683
|
170 180
....*....|....*....|....*...
gi 1958674738 323 LKIWRLNRGLEEKPEGDKHSIVGWTSQK 350
Cdd:PLN00181 684 LKLWDLSMSISGINETPLHSFMGHTNVK 711
|
|
| WD40 |
pfam00400 |
WD domain, G-beta repeat; |
288-326 |
9.24e-06 |
|
WD domain, G-beta repeat;
Pssm-ID: 459801 [Multi-domain] Cd Length: 39 Bit Score: 42.72 E-value: 9.24e-06
10 20 30
....*....|....*....|....*....|....*....
gi 1958674738 288 WHPPTVLLGHSQEVTSVCWCPSDfTKIATCSDDNTLKIW 326
Cdd:pfam00400 1 GKLLKTLEGHTGSVTSLAFSPDG-KLLASGSDDGTVKVW 38
|
|
|
|
Name |
Accession |
Description |
Interval |
E-value |
| WD40 |
COG2319 |
WD40 repeat [General function prediction only]; |
3-329 |
6.84e-37 |
|
WD40 repeat [General function prediction only];
Pssm-ID: 441893 [Multi-domain] Cd Length: 403 Bit Score: 142.74 E-value: 6.84e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958674738 3 HILAVANEEGFVRLYNTESQTskktCFKEWMAHWNAVFDLAWVPGELKLVTAAGDQTAKFWDVKAGELMGTCKGHQCSLK 82
Cdd:COG2319 133 KTLASGSADGTVRLWDLATGK----LLRTLTGHSGAVTSVAFSPDGKLLASGSDDGTVRLWDLATGKLLRTLTGHTGAVR 208
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958674738 83 SVAFSKFQKAVFcTGGRDGNIMIWDTrcnkkdgfyrqvnqisgahntadkqtpskpkkkQNSKGLAPSVDSQQSVTVVLF 162
Cdd:COG2319 209 SVAFSPDGKLLA-SGSADGTVRLWDL---------------------------------ATGKLLRTLTGHSGSVRSVAF 254
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958674738 163 -QDENTVVSAGAvDGIIKVWDLRknytayrqepiasksflyPGTSTRKLGY-----SSLVLDSTGSTLFANCTDDNIYMF 236
Cdd:COG2319 255 sPDGRLLASGSA-DGTVRLWDLA------------------TGELLRTLTGhsggvNSVAFSPDGKLLASGSDDGTVRLW 315
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958674738 237 NMTGLKtsPLAVFNGHQNSTFYVksSLSPDDQFLISGSSDEAAYIWKVSmPWHPPTVLLGHSQEVTSVCWCPsDFTKIAT 316
Cdd:COG2319 316 DLATGK--LLRTLTGHTGAVRSV--AFSPDGKTLASGSDDGTVRLWDLA-TGELLRTLTGHTGAVTSVAFSP-DGRTLAS 389
|
330
....*....|...
gi 1958674738 317 CSDDNTLKIWRLN 329
Cdd:COG2319 390 GSADGTVRLWDLA 402
|
|
| WD40 |
cd00200 |
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ... |
3-327 |
1.66e-36 |
|
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.
Pssm-ID: 238121 [Multi-domain] Cd Length: 289 Bit Score: 138.62 E-value: 1.66e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958674738 3 HILAVANEEGFVRLYNTESQTSKKTCfkewMAHWNAVFDLAWVPGELKLVTAAGDQTAKFWDVKAGELMGTCKGHQCSLK 82
Cdd:cd00200 22 KLLATGSGDGTIKVWDLETGELLRTL----KGHTGPVRDVAASADGTYLASGSSDKTIRLWDLETGECVRTLTGHTSYVS 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958674738 83 SVAFSKFQKaVFCTGGRDGNIMIWDTRCNKkdgfyrQVNQISGaHNtadkqtpskpkkkqnskglapsvdsqQSVTVVLF 162
Cdd:cd00200 98 SVAFSPDGR-ILSSSSRDKTIKVWDVETGK------CLTTLRG-HT--------------------------DWVNSVAF 143
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958674738 163 QDENTVVSAGAVDGIIKVWDLRKNYTAYRqepiasksflYPGtstRKLGYSSLVLDSTGSTLFANCTDDNIYMFNMTGLK 242
Cdd:cd00200 144 SPDGTFVASSSQDGTIKLWDLRTGKCVAT----------LTG---HTGEVNSVAFSPDGEKLLSSSSDGTIKLWDLSTGK 210
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958674738 243 TspLAVFNGHQNSTFYVksSLSPDDQFLISGSSDEAAYIWKVsMPWHPPTVLLGHSQEVTSVCWCPsDFTKIATCSDDNT 322
Cdd:cd00200 211 C--LGTLRGHENGVNSV--AFSPDGYLLASGSEDGTIRVWDL-RTGECVQTLSGHTNSVTSLAWSP-DGKRLASGSADGT 284
|
....*
gi 1958674738 323 LKIWR 327
Cdd:cd00200 285 IRIWD 289
|
|
| WD40 |
COG2319 |
WD40 repeat [General function prediction only]; |
3-333 |
3.33e-33 |
|
WD40 repeat [General function prediction only];
Pssm-ID: 441893 [Multi-domain] Cd Length: 403 Bit Score: 131.96 E-value: 3.33e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958674738 3 HILAVANEEGFVRLYNTESqtskKTCFKEWMAHWNAVFDLAWVPGELKLVTAAGDQTAKFWDVKAGELMGTCKGHQCSLK 82
Cdd:COG2319 91 RLLASASADGTVRLWDLAT----GLLLRTLTGHTGAVRSVAFSPDGKTLASGSADGTVRLWDLATGKLLRTLTGHSGAVT 166
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958674738 83 SVAFSKFQKAVFcTGGRDGNIMIWDTRcnkkDGfyRQVNQISGahntadkqtpskpkkkqnskglapsvdSQQSVTVVLF 162
Cdd:COG2319 167 SVAFSPDGKLLA-SGSDDGTVRLWDLA----TG--KLLRTLTG---------------------------HTGAVRSVAF 212
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958674738 163 -QDENTVVSAGAvDGIIKVWDLRknytayRQEPIASksflYPGTSTrklGYSSLVLDSTGSTLFANCTDDNIYMFNMTGL 241
Cdd:COG2319 213 sPDGKLLASGSA-DGTVRLWDLA------TGKLLRT----LTGHSG---SVRSVAFSPDGRLLASGSADGTVRLWDLATG 278
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958674738 242 KtsPLAVFNGHQNSTFYVksSLSPDDQFLISGSSDEAAYIWKVSMPWhPPTVLLGHSQEVTSVCWCPsDFTKIATCSDDN 321
Cdd:COG2319 279 E--LLRTLTGHSGGVNSV--AFSPDGKLLASGSDDGTVRLWDLATGK-LLRTLTGHTGAVRSVAFSP-DGKTLASGSDDG 352
|
330
....*....|..
gi 1958674738 322 TLKIWRLNRGLE 333
Cdd:COG2319 353 TVRLWDLATGEL 364
|
|
| WD40 |
COG2319 |
WD40 repeat [General function prediction only]; |
35-331 |
5.77e-29 |
|
WD40 repeat [General function prediction only];
Pssm-ID: 441893 [Multi-domain] Cd Length: 403 Bit Score: 119.63 E-value: 5.77e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958674738 35 HWNAVFDLAWVPGELKLVTAAGDQTAKFWDVKAGELMGTCKGHQCSLKSVAFSKFQKAVFcTGGRDGNIMIWDTRcnkkD 114
Cdd:COG2319 77 HTAAVLSVAFSPDGRLLASASADGTVRLWDLATGLLLRTLTGHTGAVRSVAFSPDGKTLA-SGSADGTVRLWDLA----T 151
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958674738 115 GfyRQVNQISGaHntadkqtpskpkkkqnskglapsvdsQQSVTVVLF-QDENTVVSAGAvDGIIKVWDLRKNytayrqE 193
Cdd:COG2319 152 G--KLLRTLTG-H--------------------------SGAVTSVAFsPDGKLLASGSD-DGTVRLWDLATG------K 195
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958674738 194 PIASksflYPGTSTRKlgySSLVLDSTGSTLFANCTDDNIYMFNMTGLKtsPLAVFNGHQNSTFYVksSLSPDDQFLISG 273
Cdd:COG2319 196 LLRT----LTGHTGAV---RSVAFSPDGKLLASGSADGTVRLWDLATGK--LLRTLTGHSGSVRSV--AFSPDGRLLASG 264
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*...
gi 1958674738 274 SSDEAAYIWKVSmPWHPPTVLLGHSQEVTSVCWCPsDFTKIATCSDDNTLKIWRLNRG 331
Cdd:COG2319 265 SADGTVRLWDLA-TGELLRTLTGHSGGVNSVAFSP-DGKLLASGSDDGTVRLWDLATG 320
|
|
| WD40 |
COG2319 |
WD40 repeat [General function prediction only]; |
34-331 |
1.73e-23 |
|
WD40 repeat [General function prediction only];
Pssm-ID: 441893 [Multi-domain] Cd Length: 403 Bit Score: 103.45 E-value: 1.73e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958674738 34 AHWNAVFDLAWVPGELKLVTAAGDQTAKFWDVKAGELMGTCKGHQCSLKSVAFSkFQKAVFCTGGRDGNIMIWDTrcnkk 113
Cdd:COG2319 34 GLAAAVASLAASPDGARLAAGAGDLTLLLLDAAAGALLATLLGHTAAVLSVAFS-PDGRLLASASADGTVRLWDL----- 107
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958674738 114 dgfyrqvnqisgahntadkqtpskpkkkQNSKGLAPSVDSQQSVTVVLF-QDENTVVSAGAvDGIIKVWDLRknytayRQ 192
Cdd:COG2319 108 ----------------------------ATGLLLRTLTGHTGAVRSVAFsPDGKTLASGSA-DGTVRLWDLA------TG 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958674738 193 EPIASksflYPGTSTRklgYSSLVLDSTGSTLFANCTDDNIYMFNMTGLKtsPLAVFNGHQNStfyVKS-SLSPDDQFLI 271
Cdd:COG2319 153 KLLRT----LTGHSGA---VTSVAFSPDGKLLASGSDDGTVRLWDLATGK--LLRTLTGHTGA---VRSvAFSPDGKLLA 220
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958674738 272 SGSSDEAAYIWKVSmPWHPPTVLLGHSQEVTSVCWCPsDFTKIATCSDDNTLKIWRLNRG 331
Cdd:COG2319 221 SGSADGTVRLWDLA-TGKLLRTLTGHSGSVRSVAFSP-DGRLLASGSADGTVRLWDLATG 278
|
|
| WD40 |
cd00200 |
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ... |
70-331 |
2.43e-20 |
|
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.
Pssm-ID: 238121 [Multi-domain] Cd Length: 289 Bit Score: 91.63 E-value: 2.43e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958674738 70 LMGTCKGHQCSLKSVAFSKFQKaVFCTGGRDGNIMIWDTrcNKKDGFYRQVNQISGAhntadkqtpskpkkkqnskglap 149
Cdd:cd00200 1 LRRTLKGHTGGVTCVAFSPDGK-LLATGSGDGTIKVWDL--ETGELLRTLKGHTGPV----------------------- 54
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958674738 150 svdsqqsVTVVLFQDENTVVSAGAvDGIIKVWDLRKNYTAYRQEpiasksflypgtstrklGYSSLVLD---STGSTLFA 226
Cdd:cd00200 55 -------RDVAASADGTYLASGSS-DKTIRLWDLETGECVRTLT-----------------GHTSYVSSvafSPDGRILS 109
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958674738 227 NCTDDN-IYMFNMTglKTSPLAVFNGHQNStfyVKS-SLSPDDQFLISGSSDEAAYIWKVSmPWHPPTVLLGHSQEVTSV 304
Cdd:cd00200 110 SSSRDKtIKVWDVE--TGKCLTTLRGHTDW---VNSvAFSPDGTFVASSSQDGTIKLWDLR-TGKCVATLTGHTGEVNSV 183
|
250 260
....*....|....*....|....*..
gi 1958674738 305 CWCPsDFTKIATCSDDNTLKIWRLNRG 331
Cdd:cd00200 184 AFSP-DGEKLLSSSSDGTIKLWDLSTG 209
|
|
| WD40 |
smart00320 |
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ... |
287-326 |
3.87e-07 |
|
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.
Pssm-ID: 197651 [Multi-domain] Cd Length: 40 Bit Score: 46.92 E-value: 3.87e-07
10 20 30 40
....*....|....*....|....*....|....*....|
gi 1958674738 287 PWHPPTVLLGHSQEVTSVCWCPsDFTKIATCSDDNTLKIW 326
Cdd:smart00320 1 SGELLKTLKGHTGPVTSVAFSP-DGKYLASGSDDGTIKLW 39
|
|
| PLN00181 |
PLN00181 |
protein SPA1-RELATED; Provisional |
169-350 |
9.61e-07 |
|
protein SPA1-RELATED; Provisional
Pssm-ID: 177776 [Multi-domain] Cd Length: 793 Bit Score: 52.01 E-value: 9.61e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958674738 169 VSAGAVDGIIKVWDLRKNYTAYRQEPIASKSFlypgtstrklgysSLVLDSTGSTLFANCTDDNiymfnmtglKTSPLAV 248
Cdd:PLN00181 548 VASSNFEGVVQVWDVARSQLVTEMKEHEKRVW-------------SIDYSSADPTLLASGSDDG---------SVKLWSI 605
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958674738 249 FNGHQNSTFYVKSSLS----PDD--QFLISGSSDEAAYIWKVSMPWHPPTVLLGHSQEVTSVCWCpsDFTKIATCSDDNT 322
Cdd:PLN00181 606 NQGVSIGTIKTKANICcvqfPSEsgRSLAFGSADHKVYYYDLRNPKLPLCTMIGHSKTVSYVRFV--DSSTLVSSSTDNT 683
|
170 180
....*....|....*....|....*...
gi 1958674738 323 LKIWRLNRGLEEKPEGDKHSIVGWTSQK 350
Cdd:PLN00181 684 LKLWDLSMSISGINETPLHSFMGHTNVK 711
|
|
| PLN00181 |
PLN00181 |
protein SPA1-RELATED; Provisional |
57-321 |
4.65e-06 |
|
protein SPA1-RELATED; Provisional
Pssm-ID: 177776 [Multi-domain] Cd Length: 793 Bit Score: 50.09 E-value: 4.65e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958674738 57 DQTAKFWDVKAGELMGTCKGHQCSLKSVAFSKFQKAVFCTGGRDGNIMIWDTRCNKKDGfyrqvnQISGAHNTADKQTPS 136
Cdd:PLN00181 554 EGVVQVWDVARSQLVTEMKEHEKRVWSIDYSSADPTLLASGSDDGSVKLWSINQGVSIG------TIKTKANICCVQFPS 627
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958674738 137 kpkkkqnskglapsvDSQQSVTVvlfqdentvvsaGAVDGIIKVWDLRKNytayrQEPIASksflypgtstrKLGYSSLV 216
Cdd:PLN00181 628 ---------------ESGRSLAF------------GSADHKVYYYDLRNP-----KLPLCT-----------MIGHSKTV 664
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958674738 217 -----LDStgSTLFANCTDDNIYMFNM----TGLKTSPLAVFNGHQNSTFYVksSLSPDDQFLISGSSDEAAYIWKVSMP 287
Cdd:PLN00181 665 syvrfVDS--STLVSSSTDNTLKLWDLsmsiSGINETPLHSFMGHTNVKNFV--GLSVSDGYIATGSETNEVFVYHKAFP 740
|
250 260 270 280
....*....|....*....|....*....|....*....|....*.
gi 1958674738 288 WHPPTVLLGH------------SQEVTSVCWCPSDFTKIATCSDDN 321
Cdd:PLN00181 741 MPVLSYKFKTidpvsglevddaSQFISSVCWRGQSSTLVAANSTGN 786
|
|
| WD40 |
pfam00400 |
WD domain, G-beta repeat; |
288-326 |
9.24e-06 |
|
WD domain, G-beta repeat;
Pssm-ID: 459801 [Multi-domain] Cd Length: 39 Bit Score: 42.72 E-value: 9.24e-06
10 20 30
....*....|....*....|....*....|....*....
gi 1958674738 288 WHPPTVLLGHSQEVTSVCWCPSDfTKIATCSDDNTLKIW 326
Cdd:pfam00400 1 GKLLKTLEGHTGSVTSLAFSPDG-KLLASGSDDGTVKVW 38
|
|
| WD40 |
cd00200 |
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ... |
293-335 |
1.82e-05 |
|
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.
Pssm-ID: 238121 [Multi-domain] Cd Length: 289 Bit Score: 46.94 E-value: 1.82e-05
10 20 30 40
....*....|....*....|....*....|....*....|...
gi 1958674738 293 VLLGHSQEVTSVCWCPsDFTKIATCSDDNTLKIWRLNRGLEEK 335
Cdd:cd00200 4 TLKGHTGGVTCVAFSP-DGKLLATGSGDGTIKVWDLETGELLR 45
|
|
| WD40 |
smart00320 |
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ... |
68-107 |
8.31e-05 |
|
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.
Pssm-ID: 197651 [Multi-domain] Cd Length: 40 Bit Score: 40.37 E-value: 8.31e-05
10 20 30 40
....*....|....*....|....*....|....*....|
gi 1958674738 68 GELMGTCKGHQCSLKSVAFSKFQKaVFCTGGRDGNIMIWD 107
Cdd:smart00320 2 GELLKTLKGHTGPVTSVAFSPDGK-YLASGSDDGTIKLWD 40
|
|
| WD40 |
pfam00400 |
WD domain, G-beta repeat; |
68-107 |
4.80e-04 |
|
WD domain, G-beta repeat;
Pssm-ID: 459801 [Multi-domain] Cd Length: 39 Bit Score: 38.10 E-value: 4.80e-04
10 20 30 40
....*....|....*....|....*....|....*....|
gi 1958674738 68 GELMGTCKGHQCSLKSVAFSKFQKaVFCTGGRDGNIMIWD 107
Cdd:pfam00400 1 GKLLKTLEGHTGSVTSLAFSPDGK-LLASGSDDGTVKVWD 39
|
|
| WD40 |
smart00320 |
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ... |
25-64 |
3.82e-03 |
|
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.
Pssm-ID: 197651 [Multi-domain] Cd Length: 40 Bit Score: 35.37 E-value: 3.82e-03
10 20 30 40
....*....|....*....|....*....|....*....|
gi 1958674738 25 KKTCFKEWMAHWNAVFDLAWVPGELKLVTAAGDQTAKFWD 64
Cdd:smart00320 1 SGELLKTLKGHTGPVTSVAFSPDGKYLASGSDDGTIKLWD 40
|
|
| WD40 |
pfam00400 |
WD domain, G-beta repeat; |
26-64 |
7.14e-03 |
|
WD domain, G-beta repeat;
Pssm-ID: 459801 [Multi-domain] Cd Length: 39 Bit Score: 34.63 E-value: 7.14e-03
10 20 30
....*....|....*....|....*....|....*....
gi 1958674738 26 KTCFKEWMAHWNAVFDLAWVPGELKLVTAAGDQTAKFWD 64
Cdd:pfam00400 1 GKLLKTLEGHTGSVTSLAFSPDGKLLASGSDDGTVKVWD 39
|
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|