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Conserved domains on  [gi|1958689427|ref|XP_038950826|]
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transmembrane protein 221 isoform X2 [Rattus norvegicus]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Jiraiya super family cl20912
Jiraiya; Jiraiya inhibits bone morphogenetic protein (BMP) signaling during embryogenesis. The ...
 94-186 4.23e-19

Jiraiya; Jiraiya inhibits bone morphogenetic protein (BMP) signaling during embryogenesis. The human member of this family is TMEM221.


The actual alignment was detected with superfamily member pfam15038:

Pssm-ID: 464461  Cd Length: 170  Bit Score: 82.36  E-value: 4.23e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958689427  94 HLGAELARG-PGPGRSDWFLYDCRLLRHSALGLFCCGVSVYLAALAIYALLLFEIEAGAAAASILGSGALILVAIMTHTL 172
Cdd:pfam15038  77 LFAVKLCKGpPGPDRADKFLLDSRASRHVAVGGFFISIPVFLTGLILYTLLLFESTPAIATSIIIGVGIVVCGAAMVHNL 156

                          90
                  ....*....|....
gi 1958689427 173 FRAVQATRRGLREL 186
Cdd:pfam15038 157 LVWQREKTISVREL 170
 
Name Accession Description Interval E-value
Jiraiya pfam15038
Jiraiya; Jiraiya inhibits bone morphogenetic protein (BMP) signaling during embryogenesis. The ...
 94-186 4.23e-19

Jiraiya; Jiraiya inhibits bone morphogenetic protein (BMP) signaling during embryogenesis. The human member of this family is TMEM221.


Pssm-ID: 464461  Cd Length: 170  Bit Score: 82.36  E-value: 4.23e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958689427  94 HLGAELARG-PGPGRSDWFLYDCRLLRHSALGLFCCGVSVYLAALAIYALLLFEIEAGAAAASILGSGALILVAIMTHTL 172
Cdd:pfam15038  77 LFAVKLCKGpPGPDRADKFLLDSRASRHVAVGGFFISIPVFLTGLILYTLLLFESTPAIATSIIIGVGIVVCGAAMVHNL 156

                          90
                  ....*....|....
gi 1958689427 173 FRAVQATRRGLREL 186
Cdd:pfam15038 157 LVWQREKTISVREL 170
 
Name Accession Description Interval E-value
Jiraiya pfam15038
Jiraiya; Jiraiya inhibits bone morphogenetic protein (BMP) signaling during embryogenesis. The ...
 94-186 4.23e-19

Jiraiya; Jiraiya inhibits bone morphogenetic protein (BMP) signaling during embryogenesis. The human member of this family is TMEM221.


Pssm-ID: 464461  Cd Length: 170  Bit Score: 82.36  E-value: 4.23e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958689427  94 HLGAELARG-PGPGRSDWFLYDCRLLRHSALGLFCCGVSVYLAALAIYALLLFEIEAGAAAASILGSGALILVAIMTHTL 172
Cdd:pfam15038  77 LFAVKLCKGpPGPDRADKFLLDSRASRHVAVGGFFISIPVFLTGLILYTLLLFESTPAIATSIIIGVGIVVCGAAMVHNL 156

                          90
                  ....*....|....
gi 1958689427 173 FRAVQATRRGLREL 186
Cdd:pfam15038 157 LVWQREKTISVREL 170
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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