|
Name |
Accession |
Description |
Interval |
E-value |
| PTZ00419 |
PTZ00419 |
valyl-tRNA synthetase-like protein; Provisional |
18-923 |
0e+00 |
|
valyl-tRNA synthetase-like protein; Provisional
Pssm-ID: 240411 [Multi-domain] Cd Length: 995 Bit Score: 1299.59 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 18 STQQSVPFRHRMRGETTLWNPGCDHAGIATQVVVEKKLWKERGLNRHQLGREAFLQEVWKWKAEKGDRIYHQLKKLGSSL 97
Cdd:PTZ00419 84 AIQDSLIRYHRMKGDETLWVPGTDHAGIATQVVVEKKLMKEENKTRHDLGREEFLKKVWEWKDKHGNNICNQLRRLGSSL 163
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 98 DWDRACFTMDPKLSATVTEAFVRLHEEGVIYRSTRLVNWSCTLNSAISDIEVDKKELTGRTLLSVPGYKEKVEFGVLVSF 177
Cdd:PTZ00419 164 DWSREVFTMDEQRSKAVKEAFVRLYEDGLIYRDTRLVNWCCYLKTAISDIEVEFEEIEKPTKITIPGYDKKVEVGVLWHF 243
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 178 AYKVQGSDsDEEVVVATTRIETMLGDVAVAVHPKDPRYQHLKGKSVVHPFLS-RSLPIVFDD-FVDMEFGTGAVKITPAH 255
Cdd:PTZ00419 244 AYPLEDSG-QEEIVVATTRIETMLGDVAVAVHPKDERYKKLHGKELIHPFIPdRKIPIIADDeLVDMEFGTGAVKITPAH 322
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 256 DQNDYEVGQRHRLEAISIMDSKGALVNVPPPFLGLPRFEARKAVLAALKEQGLFRGIKDNPMVVPLCNRSKDVVEPLLRP 335
Cdd:PTZ00419 323 DPNDYEIAKRHNLPFINIFTLDGKINENGGEFAGMHRFDCRRKIEEELKEMGLLRDKVPNPMRLPRCSRSGDIVEPMLIP 402
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 336 QWYVRCGEMAQAASAAVTRGDLRILPEAHQRTWHSWMDNIRDWCISRQLWWGHRIPAYFITVHD-PAVPPGEDPdgryWV 414
Cdd:PTZ00419 403 QWYVNCKDMAKRAVEAVRNGELKIIPSSHENVWYHWLENIQDWCISRQLWWGHRIPAYRVISKGpETDPSDEEP----WV 478
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 415 SGRTEAEAREKAAREFGVSPDKISLQQDEDVLDTWFSSGLFPFSIFGWPNQSEDLSVFYPGTLLETGHDILFFWVARMVM 494
Cdd:PTZ00419 479 VARSEEEALEKAKKKFGLSEEDFELEQDEDVLDTWFSSGLFPFSTLGWPDQTDDLQRFFPTSLLETGSDILFFWVARMVM 558
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 495 LGLKLTEKLPFREVYLHAIVRDAHGRKMSKSLGNVIDPLDVIHGVSLQGLHDQLLNSNLDPSEVEKAKEGQRADFPAGIP 574
Cdd:PTZ00419 559 MSLHLTDKLPFKTVFLHAMVRDSQGEKMSKSKGNVIDPLEVIEGISLQDLNQKLYEGNLPEKEIKRAIELQKKEFPNGIP 638
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 575 ECGTDALRFGLCAYTSQGRDINLDVNRILGYRHFCNKLWNATKFALRGLGKGFVPSPT--SKPEGHESL--VDRWIRSRL 650
Cdd:PTZ00419 639 ECGTDALRFGLLAYTQQGRNINLDINRVVGYRHFCNKLWNAVKFALMKLLKDFNLPNStlFKPNNVESLpwEDKWILHRL 718
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 651 AEAVRLSNEGFQAYDFPAVTTAQYSFWLYELCDVYLECLKPVLN-GVDQVAADCARQTLYTCLDVGLRLLSPFMPFVTEE 729
Cdd:PTZ00419 719 NVAIKEVTEGFKEYDFSEATQATYNFWLYELCDVYLELIKPRLSkQSDGERKQHAQDVLHTVLDIGLRLLHPMMPFITEE 798
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 730 LFQRLPRRtPNAPASLCVTPYPEPSeCSWKDPEAEAALELALSITRAVRSLRADYNLT-RTRPDCFLEVADEATGALASA 808
Cdd:PTZ00419 799 LYQRLPNY-LRKSESISIAKYPQPN-PGWNNEALDEEMKIIMSIVKSIRSLIATLGIPnKTKPDCYVTAKDAELIELIES 876
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 809 VSAYVQTLASAG---VVAVLALGAPAPQGCAVAVASDRCSIHLQLQGLVDPARELGKLQAKRSEAQRQAQRLQERRAASG 885
Cdd:PTZ00419 877 AENLISTLAKIGsvsVIPPIEEEAEVPKGCGFDVVDNKVIIYLNLDEFIDLKKELAKLEKKLAKLQKSLESYLKKISIPN 956
|
890 900 910
....*....|....*....|....*....|....*...
gi 1958756457 886 YSAKVPLEVQEADEVKLQQTEAELRKVDEAIALFQKML 923
Cdd:PTZ00419 957 YEDKVPEDVRKLNDEKIDELNEEIKQLEQAIEELKSLL 994
|
|
| ValS |
COG0525 |
Valyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Valyl-tRNA synthetase ... |
26-917 |
0e+00 |
|
Valyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Valyl-tRNA synthetase is part of the Pathway/BioSystem: Aminoacyl-tRNA synthetases
Pssm-ID: 440291 [Multi-domain] Cd Length: 877 Bit Score: 1092.40 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 26 RHRMRGETTLWNPGCDHAGIATQVVVEKKLwKERGLNRHQLGREAFLQEVWKWKAEKGDRIYHQLKKLGSSLDWDRACFT 105
Cdd:COG0525 67 YKRMQGYNTLWQPGTDHAGIATQAVVERQL-AEEGKSRHDLGREKFLERVWEWKEESGGTITNQLRRLGASCDWSRERFT 145
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 106 MDPKLSATVTEAFVRLHEEGVIYRSTRLVNWSCTLNSAISDIEVDkkeltgrtllsvpgYKEKVefGVLVSFAYKVqgSD 185
Cdd:COG0525 146 MDEGLSKAVREVFVRLYEKGLIYRGKRLVNWDPKLKTALSDLEVE--------------HEEVK--GHLWHIRYPL--AD 207
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 186 SDEEVVVATTRIETMLGDVAVAVHPKDPRYQHLKGKSVVHPFLSRSLPIVFDDFVDMEFGTGAVKITPAHDQNDYEVGQR 265
Cdd:COG0525 208 GSGYIVVATTRPETMLGDTAVAVHPEDERYKHLIGKTVILPLVGREIPIIADEYVDPEFGTGAVKITPAHDPNDFEVGKR 287
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 266 HRLEAISIMDSKGALVNVPPPFLGLPRFEARKAVLAALKEQGLFRGIKDNPMVVPLCNRSKDVVEPLLRPQWYVRCGEMA 345
Cdd:COG0525 288 HNLPMINILDEDGTINENAGKYRGLDRFEARKAIVADLEELGLLVKVEPHKHSVGHSDRSGTVIEPYLSDQWFVKMKPLA 367
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 346 QAASAAVTRGDLRILPEAHQRTWHSWMDNIRDWCISRQLWWGHRIPAYFitvhdpavppgeDPDGRYWVSgRTEAEAREK 425
Cdd:COG0525 368 KPAIEAVEDGEIKFVPERWEKTYFHWMENIRDWCISRQLWWGHRIPAWY------------CPDGEVYVA-RTEPEACAK 434
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 426 AarefgvspDKISLQQDEDVLDTWFSSGLFPFSIFGWPNQSEDLSVFYPGTLLETGHDILFFWVARMVMLGLKLTEKLPF 505
Cdd:COG0525 435 A--------GSVNLTQDEDVLDTWFSSALWPFSTLGWPEKTEDLKYFYPTSVLVTGFDIIFFWVARMIMMGLHFTGEVPF 506
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 506 REVYLHAIVRDAHGRKMSKSLGNVIDPLDVIhgvslqglhDQLlnsnldpsevekakegqradfpagipecGTDALRFGL 585
Cdd:COG0525 507 KDVYIHGLVRDEQGRKMSKSKGNVIDPLDLI---------DKY----------------------------GADALRFTL 549
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 586 CAYTSQGRDINLDVNRILGYRHFCNKLWNATKFALrGLGKGFVPSPTSKPEgHESLVDRWIRSRLAEAVRLSNEGFQAYD 665
Cdd:COG0525 550 AALASPGRDIKFDEERVEGYRNFANKLWNASRFVL-MNLEGFDPGLDPDPE-ELSLADRWILSRLNKTIAEVTEALEKYR 627
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 666 FPAVTTAQYSF-WlYELCDVYLECLKPVLNGVDQVAADCARQTLYTCLDVGLRLLSPFMPFVTEELFQRLPRRTPNapAS 744
Cdd:COG0525 628 FDEAAQALYDFvW-NEFCDWYLELAKPRLYGGDEAAKRETRATLVYVLEQILRLLHPFMPFITEEIWQKLPPRKEG--ES 704
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 745 LCVTPYPEPSEcSWKDPEAEAALELALSITRAVRSLRADYNLT-RTRPDCFLEVADEATGALASAVSAYVQTLASAGVVA 823
Cdd:COG0525 705 IMLAPWPEADE-ELIDEEAEAEFEWLKEVISAIRNIRAEMNIPpSKKLPLLLKGADEADRARLEENAAYIKRLARLEEIT 783
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 824 VLAlgAPAPQGCAVAVASDrCSIHLQLQGLVDPARELGKLQAKRSEAQRQAQRLQERRAASGYSAKVPLEVQEADEVKLQ 903
Cdd:COG0525 784 ILV--DEKPEGAASAVVGG-AEVFLPLEGLIDVEAERARLEKELAKLEKEIARVEKKLSNEGFVAKAPAEVVEKEREKLA 860
|
890
....*....|....
gi 1958756457 904 QTEAELRKVDEAIA 917
Cdd:COG0525 861 EAEAKLEKLEEQLA 874
|
|
| valS |
PRK05729 |
valyl-tRNA synthetase; Reviewed |
26-921 |
0e+00 |
|
valyl-tRNA synthetase; Reviewed
Pssm-ID: 235582 [Multi-domain] Cd Length: 874 Bit Score: 1058.94 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 26 RHRMRGETTLWNPGCDHAGIATQVVVEKKLWKErGLNRHQLGREAFLQEVWKWKAEKGDRIYHQLKKLGSSLDWDRACFT 105
Cdd:PRK05729 68 YKRMQGYNTLWLPGTDHAGIATQMVVERQLAAE-GKSRHDLGREKFLEKVWEWKEESGGTITNQLRRLGASCDWSRERFT 146
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 106 MDPKLSATVTEAFVRLHEEGVIYRSTRLVNWSCTLNSAISDIEVDkkeltgrtllsvpgYKEkVEfGVLVSFAYKVqgSD 185
Cdd:PRK05729 147 MDEGLSKAVREVFVRLYEKGLIYRGKRLVNWDPKLQTALSDLEVE--------------YKE-VK-GKLWHIRYPL--AD 208
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 186 SDEEVVVATTRIETMLGDVAVAVHPKDPRYQHLKGKSVVHPFLSRSLPIVFDDFVDMEFGTGAVKITPAHDQNDYEVGQR 265
Cdd:PRK05729 209 GSDYLVVATTRPETMLGDTAVAVNPEDERYKHLIGKTVILPLVGREIPIIADEYVDPEFGTGAVKITPAHDPNDFEVGKR 288
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 266 HRLEAISIMDSKGALVNVPPPFLGLPRFEARKAVLAALKEQGLFRGIKDNPMVVPLCNRSKDVVEPLLRPQWYVRCGEMA 345
Cdd:PRK05729 289 HNLPMINIMDEDGTINENPGEYQGLDRFEARKAIVADLEELGLLVKIEPHTHSVGHSDRSGVVIEPYLSDQWFVKMKPLA 368
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 346 QAASAAVTRGDLRILPEAHQRTWHSWMDNIRDWCISRQLWWGHRIPAYFitvhdpavppgeDPDGRYWVsGRTEAEAREK 425
Cdd:PRK05729 369 KPALEAVENGEIKFVPERWEKTYFHWMENIQDWCISRQLWWGHRIPAWY------------DEDGEVYV-GREEPEAREK 435
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 426 AArefgvspdkisLQQDEDVLDTWFSSGLFPFSIFGWPNQSEDLSVFYPGTLLETGHDILFFWVARMVMLGLKLTEKLPF 505
Cdd:PRK05729 436 AL-----------LTQDEDVLDTWFSSALWPFSTLGWPEKTEDLKRFYPTSVLVTGFDIIFFWVARMIMMGLHFTGQVPF 504
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 506 REVYLHAIVRDAHGRKMSKSLGNVIDPLDVIhgvslqglhDQLlnsnldpsevekakegqradfpagipecGTDALRFGL 585
Cdd:PRK05729 505 KDVYIHGLVRDEQGRKMSKSKGNVIDPLDLI---------DKY----------------------------GADALRFTL 547
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 586 CAYTSQGRDINLDVNRILGYRHFCNKLWNATKFALrgLGKGFVPSPTSKPEGHESLVDRWIRSRLAEAVRLSNEGFQAYD 665
Cdd:PRK05729 548 AALASPGRDIRFDEERVEGYRNFANKLWNASRFVL--MNLEGADVGELPDPEELSLADRWILSRLNRTVAEVTEALDKYR 625
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 666 FPAVTTAQYSFWLYELCDVYLECLKPVLNGVDQVAadcARQTLYTCLDVGLRLLSPFMPFVTEELFQRLPRRtpNAPASL 745
Cdd:PRK05729 626 FDEAARALYEFIWNEFCDWYLELAKPVLQEAAKRA---TRATLAYVLEQILRLLHPFMPFITEELWQKLAPL--GIEESI 700
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 746 CVTPYPEPSECswKDPEAEAALELALSITRAVRSLRADYNLT-RTRPDCFLEVADEATGALASAVSAYVQTLASAGVVAV 824
Cdd:PRK05729 701 MLAPWPEADEA--IDEAAEAEFEWLKELITAIRNIRAEMNIPpSKKLPLLLKGADAEDRARLEANEAYIKRLARLESLEI 778
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 825 LALGAPAPQGCAVAVASDrCSIHLQLQGLVDPARELGKLQAKRSEAQRQAQRLQERRAASGYSAKVPLEVQEADEVKLQQ 904
Cdd:PRK05729 779 LADDEEAPEGAASAVVGG-AELFLPLEGLIDVEAELARLEKELAKLEKEIERVEKKLSNEGFVAKAPEEVVEKEREKLAE 857
|
890
....*....|....*..
gi 1958756457 905 TEAELRKVDEAIALFQK 921
Cdd:PRK05729 858 YEEKLAKLKERLARLKA 874
|
|
| PLN02381 |
PLN02381 |
valyl-tRNA synthetase |
28-915 |
0e+00 |
|
valyl-tRNA synthetase
Pssm-ID: 215214 [Multi-domain] Cd Length: 1066 Bit Score: 1042.17 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 28 RMRGETTLWNPGCDHAGIATQVVVEKKLWKERGLNRHQLGREAFLQEVWKWKAEKGDRIYHQLKKLGSSLDWDRACFTMD 107
Cdd:PLN02381 162 RMSGYNALWVPGVDHAGIATQVVVEKKLMRERHLTRHDIGREEFVSEVWKWKDEYGGTILNQLRRLGASLDWSRECFTMD 241
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 108 PKLSATVTEAFVRLHEEGVIYRSTRLVNWSCTLNSAISDIEVDKKELTGRTLLSVPGYKEKVEFGVLVSFAYKVQGSDSd 187
Cdd:PLN02381 242 EQRSKAVTEAFVRLYKEGLIYRDIRLVNWDCTLRTAISDVEVDYIDIKERTLLKVPGYDKPVEFGVLTSFAYPLEGGLG- 320
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 188 eEVVVATTRIETMLGDVAVAVHPKDPRYQHLKGKSVVHPFLSRSLPIVFD-DFVDMEFGTGAVKITPAHDQNDYEVGQRH 266
Cdd:PLN02381 321 -EIVVATTRIETMLGDTAIAIHPDDERYKHLHGKFAVHPFNGRKLPIICDaILVDPNFGTGAVKITPAHDPNDFEVGKRH 399
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 267 RLEAISIMDSKGAL-VNVPPPFLGLPRFEARKAVLAALKEQGLFRGIKDNPMVVPLCNRSKDVVEPLLRPQWYVRCGEMA 345
Cdd:PLN02381 400 NLEFINIFTDDGKInSNGGSEFAGMPRFAAREAVIEALQKKGLYRGAKNNEMRLGLCSRTNDVVEPMIKPQWFVNCSSMA 479
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 346 QAASAAVTRGD---LRILPEAHQRTWHSWMDNIRDWCISRQLWWGHRIPAYFITVHDPAvppgEDPDGRY---WVSGRTE 419
Cdd:PLN02381 480 KQALDAAIDGEnkkLEFIPKQYLAEWKRWLENIRDWCISRQLWWGHRIPAWYVTLEDDQ----LKELGSYndhWVVARNE 555
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 420 AEAREKAAREFgvSPDKISLQQDEDVLDTWFSSGLFPFSIFGWPNQSEDLSVFYPGTLLETGHDILFFWVARMVMLGLKL 499
Cdd:PLN02381 556 SDALLEASQKF--PGKKFELSQDPDVLDTWFSSGLFPLSVLGWPDDTDDLKAFYPTSVLETGHDILFFWVARMVMMGMQL 633
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 500 TEKLPFREVYLHAIVRDAHGRKMSKSLGNVIDPLDVIHGVSLQGLHDQLLNSNLDPSEVEKAKEGQRADFPAGIPECGTD 579
Cdd:PLN02381 634 GGDVPFRKVYLHPMIRDAHGRKMSKSLGNVIDPLEVINGISLEGLHKRLEEGNLDPKELVVAKEGQKKDFPNGIAECGTD 713
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 580 ALRFGLCAYTSQGRDINLDVNRILGYRHFCNKLWNATKFALRGLGKGFVPSPTSKPEGHESLVdRWIRSRLAEAVRLSNE 659
Cdd:PLN02381 714 ALRFALVSYTAQSDKINLDILRVVGYRQWCNKLWNAVRFAMSKLGDDYTPPATLSVETMPFSC-KWILSVLNKAISKTVS 792
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 660 GFQAYDFPAVTTAQYSFWLYELCDVYLECLKPVLNGVDQ---VAADCARQTLYTCLDVGLRLLSPFMPFVTEELFQRLPR 736
Cdd:PLN02381 793 SLDAYEFSDAASTVYSWWQYQFCDVFIEAIKPYFAGDNPefaSERAAAQDTLWICLDTGLRLLHPFMPFVTEELWQRLPQ 872
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 737 -RTPNAPASLCVTPYPEPSEcSWKDPEAEAALELALSITRAVRSLRADYNLTRT--RPDCFLEVADEATGALASAVSAYV 813
Cdd:PLN02381 873 pKDHTRKDSIMISEYPSAVE-AWTNEKVEYEMDLVLSTVKCLRSLRAEVLEKQKneRLPAFALCRNQEIAAIIKSHQLEI 951
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 814 QTLASAGVVAVLALGAPA-PQGCAVAVASDRCSIHLQLQGLVDPARELGKLQAKRSEAQRQAQRLQERRAASGYSAKVPL 892
Cdd:PLN02381 952 LTLANLSSLKVLLSENDApPAGCAFENVNENLKVYLQAQGAVNAEAELEKLRNKMDEIQKQQEKLEKKMNASGYKEKVPA 1031
|
890 900
....*....|....*....|...
gi 1958756457 893 EVQEADEVKLQQTEAELRKVDEA 915
Cdd:PLN02381 1032 NIQEEDARKLTKLLQELEFFEKE 1054
|
|
| valS |
TIGR00422 |
valyl-tRNA synthetase; The valyl-tRNA synthetase (ValS) is a class I amino acyl-tRNA ligase ... |
27-902 |
0e+00 |
|
valyl-tRNA synthetase; The valyl-tRNA synthetase (ValS) is a class I amino acyl-tRNA ligase and is particularly closely related to the isoleucyl tRNA synthetase. [Protein synthesis, tRNA aminoacylation]
Pssm-ID: 273070 [Multi-domain] Cd Length: 861 Bit Score: 890.56 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 27 HRMRGETTLWNPGCDHAGIATQVVVEKKLWKErGLNRHQLGREAFLQEVWKWKAEKGDRIYHQLKKLGSSLDWDRACFTM 106
Cdd:TIGR00422 66 KRMKGYNVLWLPGTDHAGIATQVKVEKKLGAE-GKTKHDLGREEFREKIWEWKEESGGTIKNQIKRLGASLDWSRERFTM 144
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 107 DPKLSATVTEAFVRLHEEGVIYRSTRLVNWSCTLNSAISDIEVDKKELTGrtllSVPGYKEKVEFGvlvsfaykvqgsdS 186
Cdd:TIGR00422 145 DEGLSKAVKEAFVRLYEKGLIYRGEYLVNWDPKLNTAISDIEVEYKEVKG----KLYYIRYPLANG-------------S 207
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 187 DEEVVVATTRIETMLGDVAVAVHPKDPRYQHLKGKSVVHPFLSRSLPIVFDDFVDMEFGTGAVKITPAHDQNDYEVGQRH 266
Cdd:TIGR00422 208 KDYLVVATTRPETMFGDTAVAVHPEDERYKHLIGKKVILPLTGRKIPIIADEYVDMEFGTGAVKVTPAHDFNDYEWGKRH 287
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 267 RLEAISIMDSKGALVNVPPPFLGLPRFEARKAVLAALKEQGLFRGIKDNPMVVPLCNRSKDVVEPLLRPQWYVRCGEMAQ 346
Cdd:TIGR00422 288 NLEFINILDEDGLLNENAGKYQGLTRFEARKKIVEDLKEEGLLVKIEPHTHNVGTCWRSGTVVEPLLSKQWFVKVEKLAD 367
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 347 AASAAVTRGDLRILPEAHQRTWHSWMDNIRDWCISRQLWWGHRIPAYFItvhdpavppgeDPDGRYWVsGRTEAEAREKA 426
Cdd:TIGR00422 368 KALEAAEEGEIKFVPKRMEKRYLNWLRNIKDWCISRQLIWGHRIPVWYC-----------KECGEVYV-AKEEPLPDDKT 435
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 427 AREFGVSpdkisLQQDEDVLDTWFSSGLFPFSIFGWPNQSEDLSVFYPGTLLETGHDILFFWVARMVMLGLKLTEKLPFR 506
Cdd:TIGR00422 436 NTGPSVE-----LEQDTDVLDTWFSSSLWPFSTLGWPDETKDLKKFYPTDLLVTGYDIIFFWVARMIFRSLALTGQVPFK 510
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 507 EVYLHAIVRDAHGRKMSKSLGNVIDPLDVIHgvslqglhdqllnsnldpsevekakegqradfpagipECGTDALRFGLC 586
Cdd:TIGR00422 511 EVYIHGLVRDEQGRKMSKSLGNVIDPLDVIE-------------------------------------KYGADALRFTLA 553
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 587 AYTSQGRDINLDVNRILGYRHFCNKLWNATKFALRGLGKgfvPSPTSKPEGHESLVDRWIRSRLAEAVRLSNEGFQAYDF 666
Cdd:TIGR00422 554 SLVTPGDDINFDWKRVESARNFLNKLWNASRFVLMNLSD---DLELSGGEEKLSLADRWILSKLNRTIKEVRKALDKYRF 630
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 667 PAVTTAQYSFWLYELCDVYLECLKPVLNGVDQVAADCARQTLYTCLDVGLRLLSPFMPFVTEELFQRLprrtPNAPASLC 746
Cdd:TIGR00422 631 AEAAKALYEFIWNDFCDWYIELVKYRLYNGNEAEKKAARDTLYYVLDKALRLLHPFMPFITEEIWQHF----KEGADSIM 706
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 747 VTPYPEPSEcSWKDPEAEAALELALSITRAVRSLRADYNLTRTRPDCFLEVADEATGALASAVSA-YVQTLASAGVVAVL 825
Cdd:TIGR00422 707 LQSYPVVDA-EFVDEEAEKAFELLKEIIVSIRNLKAESNIPPNAPLKVLLIYTEAETAERLKLNAvDIKGAINFSEVEVV 785
|
810 820 830 840 850 860 870
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1958756457 826 AlGAPaPQGCAVAVASDRCSIHLQLQGLVDPARELGKLQAKRSEAQRQAQRLQERRAASGYSAKVPLEVQEADEVKL 902
Cdd:TIGR00422 786 I-EKP-EVTEAVVELVPGFEIIIPVKGLINKAKELARLQKQLDKEKKEVIRIEGKLENEGFVKKAPKEVIEKEKEKL 860
|
|
| valS |
PRK14900 |
valyl-tRNA synthetase; Provisional |
2-918 |
0e+00 |
|
valyl-tRNA synthetase; Provisional
Pssm-ID: 237855 [Multi-domain] Cd Length: 1052 Bit Score: 786.88 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 2 LALPGPSGVAFLP---APLSTQQSVPFR-HRMRGETTLWNPGCDHAGIATQVVVEKKLWKERGLNRHQLGREAFLQEVWK 77
Cdd:PRK14900 52 IVLPPPNVTGSLHlghALTATLQDVLIRwKRMSGFNTLWLPGTDHAGIATQMIVEKELKKTEKKSRHDLGREAFLERVWA 131
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 78 WKAEKGDRIYHQLKKLGSSLDWDRACFTMDPKLSATVTEAFVRLHEEGVIYRSTRLVNWSCTLNSAISDIEVDKKEltgr 157
Cdd:PRK14900 132 WKEQYGSRIGEQHKALGASLDWQRERFTMDEGLSRAVREVFVRLHEEGLIYREKKLINWCPDCRTALSDLEVEHEE---- 207
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 158 tllsvpgykekVEFGVLVSFAYKVqgSDSDEEVVVATTRIETMLGDVAVAVHPKDPRYQHLKGKSVVHPFLSRSLPIVFD 237
Cdd:PRK14900 208 -----------AHQGELWSFAYPL--ADGSGEIVVATTRPETMLGDTAVAVHPLDPRYMALHGKKVRHPITGRTFPIVAD 274
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 238 -DFVDMEFGTGAVKITPAHDQNDYEVGQRHRLEAISIMDSKGALVNVPPPFLGLPRFEARKAVLAALKEQGLFRGIKDNP 316
Cdd:PRK14900 275 aILVDPKFGTGAVKVTPAHDFNDFEVGKRHGLEMITVIGPDGRMTAEAGPLAGLDRFEARKEVKRLLAEQGLDRGAKPHV 354
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 317 MVVPLCNRSKDVVEPLLRPQWYVRCGEMAQAASAAVTRGDLRILPEAHQRTWHSWMDNIRDWCISRQLWWGHRIPAYFIt 396
Cdd:PRK14900 355 LPLGRCQRSATILEPLLSDQWYVRIEPLARPAIEAVEQGRTRFIPEQWTNTYMAWMRNIHDWCISRQLWWGHQIPAWYC- 433
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 397 vhdpavppgedPDGRYWVSGRTEAEAREKAAREFgvspdkislQQDEDVLDTWFSSGLFPFSIFGWPNQSEDLSVFYPGT 476
Cdd:PRK14900 434 -----------PDGHVTVARETPEACSTCGKAEL---------RQDEDVLDTWFSSGLWPFSTMGWPEQTDTLRTFYPTS 493
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 477 LLETGHDILFFWVARMVMLGLKLTEKLPFREVYLHAIVRDAHGRKMSKSLGNVIDPLDVihgvslqglhdqllnsnldps 556
Cdd:PRK14900 494 VMETGHDIIFFWVARMMMMGLHFMGEVPFRTVYLHPMVRDEKGQKMSKTKGNVIDPLVI--------------------- 552
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 557 evekakegqradfpagIPECGTDALRFGLCAYTSQGRDINLDVNRILGYRHFCNKLWNATKFALRGLGkGFVPSPTSKPE 636
Cdd:PRK14900 553 ----------------TEQYGADALRFTLAALTAQGRDIKLAKERIEGYRAFANKLWNASRFALMNLS-GYQERGEDPAR 615
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 637 GHESLVDRWIRSRLAEAVRLSNEGFQAYDFPAVTTAQYSFWLYELCDVYLECLKPVLNGVDQVAADCARQTLYTCLDVGL 716
Cdd:PRK14900 616 LARTPADRWILARLQRAVNETVEALEAFRFNDAANAVYAFVWHELCDWYIELAKEALASEDPEARRSVQAVLVHCLQTSY 695
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 717 RLLSPFMPFVTEELFQRLP--RRTPNAPASLCVTPYPEPSECswkDPEAEAALELALSITRAVRSLRADYNLT-----RT 789
Cdd:PRK14900 696 RLLHPFMPFITEELWHVLRaqVGASAWADSVLAAEYPRKGEA---DEAAEAAFRPVLGIIDAVRNIRGEMGIPwkvklGA 772
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 790 RPDCFLEVADEATGALASAVS-AYVQTLASAGVVAVLALGAPAPQGCAVAVASDRCSIHLQLQGLVDPARELGKLQAKRS 868
Cdd:PRK14900 773 QAPVEIAVADPALRDLLQAGElARVHRVAGVEGSRLVVAAATAPAPQSAVGVGPGFEVRVPLAGVIDLAAETARVDKEIG 852
|
890 900 910 920 930
....*....|....*....|....*....|....*....|....*....|
gi 1958756457 869 EAQRQAQRLQERRAASGYSAKVPLEVQEADEVKLQQTEAELRKVDEAIAL 918
Cdd:PRK14900 853 KVDQDLAVLERKLQNPSFVQNAPPAVVEKDRARAEELREKRGKLEAHRAM 902
|
|
| PLN02943 |
PLN02943 |
aminoacyl-tRNA ligase |
27-922 |
0e+00 |
|
aminoacyl-tRNA ligase
Pssm-ID: 215509 [Multi-domain] Cd Length: 958 Bit Score: 655.86 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 27 HRMRGETTLWNPGCDHAGIATQVVVEKKLWKErGLNRHQLGREAFLQEVWKWKAEKGDRIYHQLKKLGSSLDWDRACFTM 106
Cdd:PLN02943 121 NRMKGRPTLWIPGTDHAGIATQLVVEKMLASE-GIKRTDLGRDEFTKRVWEWKEKYGGTITNQIKRLGASCDWSRERFTL 199
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 107 DPKLSATVTEAFVRLHEEGVIYRSTRLVNWSCTLNSAISDIEVDKKEltgrtllsvpgykekvEFGVLVSFAYKVQGSdS 186
Cdd:PLN02943 200 DEQLSRAVVEAFVRLHEKGLIYQGSYMVNWSPNLQTAVSDLEVEYSE----------------EPGTLYYIKYRVAGG-S 262
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 187 DEEVVVATTRIETMLGDVAVAVHPKDPRYQHLKGKSVVHPF-LSRSLPIVFDDFVDMEFGTGAVKITPAHDQNDYEVGQR 265
Cdd:PLN02943 263 EDFLTIATTRPETLFGDVAIAVNPEDDRYSKYIGKMAIVPMtYGRHVPIIADRYVDKDFGTGVLKISPGHDHNDYLLARK 342
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 266 HRLEAISIMDSKGALVNVPppflGLPRFEARKAVLAALKEQGLfrGIKDNP--MVVPLCNRSKDVVEPLLRPQWYVRCGE 343
Cdd:PLN02943 343 LGLPILNVMNKDGTLNEVA----GLYWFEAREKLWSDLEETGL--AVKKEPhtLRVPRSQRGGEVIEPLVSKQWFVTMEP 416
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 344 MAQAASAAVTRGDLRILPEAHQRTWHSWMDNIRDWCISRQLWWGHRIPAYFITvhdpavppGEDPDGRYWVSgRTEAEAR 423
Cdd:PLN02943 417 LAEKALKAVENGELTIIPERFEKIYNHWLSNIKDWCISRQLWWGHRIPVWYIV--------GKDCEEDYIVA-RSAEEAL 487
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 424 EKAAREFGVSpdkISLQQDEDVLDTWFSSGLFPFSIFGWPNQS-EDLSVFYPGTLLETGHDILFFWVARMVMLGLKLTEK 502
Cdd:PLN02943 488 EKAREKYGKD---VEIYQDPDVLDTWFSSALWPFSTLGWPDVSaEDFKKFYPTTVLETGHDILFFWVARMVMMGIEFTGT 564
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 503 LPFREVYLHAIVRDAHGRKMSKSLGNVIDPLDVIHgvslqglhdqllnsnldpsevekakegqradfpagipECGTDALR 582
Cdd:PLN02943 565 VPFSYVYLHGLIRDSQGRKMSKTLGNVIDPLDTIK-------------------------------------EFGTDALR 607
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 583 FGLCAYTSqGRDINLDVNRILGYRHFCNKLWNATKFALRGLgkgfvPSPTS----------KPEGHESLV-----DRWIR 647
Cdd:PLN02943 608 FTLALGTA-GQDLNLSTERLTSNKAFTNKLWNAGKFVLQNL-----PSQSDtsawehilacKFDKEESLLslplpECWVV 681
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 648 SRLAEAVRLSNEGFQAYDFPAVTTAQYSFWLYELCDVYLECLKPVLNGV-DQVAADCARQTLYTCLDVGLRLLSPFMPFV 726
Cdd:PLN02943 682 SKLHELIDSVTTSYDKYFFGDVGREIYDFFWSDFADWYIEASKTRLYHSgDNSALSRAQAVLLYVFENILKLLHPFMPFV 761
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 727 TEELFQRLPRRTpnapASLCVTPYPEPSECswKDPEAEAALELALSITRAVRSLRADYNLTRTRPDCFLEVADEATGALA 806
Cdd:PLN02943 762 TEELWQALPYRK----EALIVSPWPQTSLP--KDLKSIKRFENLQSLTRAIRNARAEYSVEPAKRISASIVASAEVIEYI 835
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 807 SAVSAYVQTLASAGVVAVLALGAP---APQGCAVaVASDRCSIHLQLQGLVDPARELGKLQAKRSEAQRQAQRLQERRAA 883
Cdd:PLN02943 836 SKEKEVLALLSRLDLQNVHFTDSPpgdANQSVHL-VASEGLEAYLPLADMVDISAEVERLSKRLSKMQTEYDALAARLSS 914
|
890 900 910
....*....|....*....|....*....|....*....
gi 1958756457 884 SGYSAKVPLEVQEADEVKLQQTEAELRKVDEAIALFQKM 922
Cdd:PLN02943 915 PKFVEKAPEDVVRGVREKAAEAEEKIKLTKNRLAFLKST 953
|
|
| tRNA-synt_1 |
pfam00133 |
tRNA synthetases class I (I, L, M and V); Other tRNA synthetase sub-families are too ... |
20-598 |
0e+00 |
|
tRNA synthetases class I (I, L, M and V); Other tRNA synthetase sub-families are too dissimilar to be included.
Pssm-ID: 459685 [Multi-domain] Cd Length: 602 Bit Score: 618.27 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 20 QQSVPFRHRMRGETTLWNPGCDHAGIATQVVVEKKLWKERGLNRHQLGREAFLQEVWKWKAEKGDRIYHQLKKLGSSLDW 99
Cdd:pfam00133 49 KDIVIRYKRMKGYYVLWVPGWDHHGLPTEQVVEKKLGIKEKKTRHKYGREEFREKCREWKMEYADEIRKQFRRLGRSIDW 128
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 100 DRACFTMDPKLSATVTEAFVRLHEEGVIYRSTRLVNWSCTLNSAISDIEVDKKELTgrtllsvpgykekvefGVLVSFAY 179
Cdd:pfam00133 129 DREYFTMDPELEAAVWEVFVRLHDKGLIYRGKKLVNWSPALNTALSNLEVEYKDVK----------------GPSIHVAF 192
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 180 KVQGsDSDEEVVVATTRIETMLGDVAVAVHP-------------------------------KDPRYQHLKGKSVVHPFL 228
Cdd:pfam00133 193 PLAD-DEGASLVIWTTTPWTLPGNTAVAVNPefdyvitgegyilaeallkslykkgtdkkilEDFRGKELEGKEAIHPFV 271
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 229 SRSLPIVFDDFVDMEFGTGAVKITPAHDQNDYEVGQRHRLEAISIMDSKGALVNVPPPFLGLPRFEARKAVLAALKEQGL 308
Cdd:pfam00133 272 NREIPIITDDYVDMEFGTGAVHIAPAHGENDYEVGQRHNLEVINPVDDDGTFTEEAPDFQGVYRFDARKKIVELLTEKGL 351
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 309 FRGIKDNPMVVPLCNRSKDVVEPLLRPQWYVRCGEMAQAASAAVTrgDLRILPEAHQRTWHSWMDNIRDWCISRQLWWGH 388
Cdd:pfam00133 352 LLKIEPFTHSYPFCWRSGTPIIPRATPQWFVRMDELADQALEAVE--KVQFVPKSGEKRYFNWLANIQDWCISRQRWWGH 429
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 389 RIPAYFITVHDPAVPPGEdpdGRYWVSGRTEAEAREKA-AREFG--VSPDKISLQQDEDVLDTWFSSGLFPFSIFGWPNQ 465
Cdd:pfam00133 430 PIPAWVSKDTEEVVCRGE---LFELVAGRFEEEGSIKWlHREAKdkLGYGKGTLEQDEDVLDTWFSSGSWPFSTLGWPFV 506
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 466 S-EDLSVFYPGTLLETGHDILFFWVARMVMLGLKLTEKLPFREVYLHAIVRDAHGRKMSKSLGNVIDPLDVIHgvslqgl 544
Cdd:pfam00133 507 NtEEFKKFFPADMLLEGSDQTRGWFYRMIMLSTALTGSVPFKNVLVHGLVRDEQGRKMSKSLGNVIDPLDVID------- 579
|
570 580 590 600 610
....*....|....*....|....*....|....*....|....*....|....
gi 1958756457 545 hdqllnsnldpsevekakegqradfpagipECGTDALRFGLCaYTSQGRDINLD 598
Cdd:pfam00133 580 ------------------------------KYGADALRLWLA-NSDYGRDINLS 602
|
|
| ValRS_core |
cd00817 |
catalytic core domain of valyl-tRNA synthetases; Valine amino-acyl tRNA synthetase (ValRS) ... |
27-597 |
0e+00 |
|
catalytic core domain of valyl-tRNA synthetases; Valine amino-acyl tRNA synthetase (ValRS) catalytic core domain. This enzyme is a monomer which aminoacylates the 2'-OH of the nucleotide at the 3' of the appropriate tRNA. The core domain is based on the Rossman fold and is responsible for the ATP-dependent formation of the enzyme bound aminoacyl-adenylate. It contains the characteristic class I HIGH and KMSKS motifs, which are involved in ATP binding. ValRS has an insertion in the core domain, which is subject to both deletions and rearrangements. This editing region hydrolyzes mischarged cognate tRNAs and thus prevents the incorporation of chemically similar amino acids.
Pssm-ID: 185677 [Multi-domain] Cd Length: 382 Bit Score: 545.30 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 27 HRMRGETTLWNPGCDHAGIATQVVVEKKLWKERGlNRHQLGREAFLQEVWKWKAEKGDRIYHQLKKLGSSLDWDRACFTM 106
Cdd:cd00817 34 KRMKGYNVLWPPGTDHAGIATQVVVEKKLGIEGK-TRHDLGREEFLEKCWEWKEESGGKIREQLKRLGASVDWSREYFTM 112
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 107 DPKLSATVTEAFVRLHEEGVIYRSTRLVNWSCTLNSAISDIEVdkkeltgrtllsvpgykekvefgvlvsfaykvqgsds 186
Cdd:cd00817 113 DPGLSRAVQEAFVRLYEKGLIYRDNRLVNWCPKLRTAISDIEV------------------------------------- 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 187 deevvvattrietmlgdvavavhpkdpryqhlkgksvvhpflsrslpivfddfvdmefgtgavkitpahdqndyevgqrh 266
Cdd:cd00817 --------------------------------------------------------------------------------
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 267 rleaisimdskgalvnvpppflglprfearkavlaalkeqglfrgikdnpmvvplCNRSKDVVEPLLRPQWYVRCGEMAQ 346
Cdd:cd00817 156 -------------------------------------------------------CSRSGDVIEPLLKPQWFVKVKDLAK 180
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 347 AASAAVTRGDLRILPEAHQRTWHSWMDNIRDWCISRQLWWGHRIPAYFItvhdpavppgedPDGRYWVSGRTEAEAREKA 426
Cdd:cd00817 181 KALEAVKEGDIKFVPERMEKRYENWLENIRDWCISRQLWWGHRIPAWYC------------KDGGHWVVAREEDEAIDKA 248
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 427 AREFGVSPDKISLQQDEDVLDTWFSSGLFPFSIFGWPNQSEDLSVFYPGTLLETGHDILFFWVARMVMLGLKLTEKLPFR 506
Cdd:cd00817 249 APEACVPCGGEELKQDEDVLDTWFSSSLWPFSTLGWPEETKDLKKFYPTSLLVTGHDIIFFWVARMIMRGLKLTGKLPFK 328
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 507 EVYLHAIVRDAHGRKMSKSLGNVIDPLDVihgvslqglhdqllnsnldpsevekakegqradfpagIPECGTDALRFGLC 586
Cdd:cd00817 329 EVYLHGLVRDEDGRKMSKSLGNVIDPLDV-------------------------------------IDGYGADALRFTLA 371
|
570
....*....|.
gi 1958756457 587 AYTSQGRDINL 597
Cdd:cd00817 372 SAATQGRDINL 382
|
|
| valS |
PRK13208 |
valyl-tRNA synthetase; Reviewed |
27-833 |
2.40e-123 |
|
valyl-tRNA synthetase; Reviewed
Pssm-ID: 237306 [Multi-domain] Cd Length: 800 Bit Score: 393.02 E-value: 2.40e-123
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 27 HRMRGETTLWNPGCDHAGIATQVVVEKKLwkerGLNRHQLGREAFLQ--EVWKWKAEKGDRiyHQLKKLGSSLDWDRACF 104
Cdd:PRK13208 71 QRMRGYNVFFPQGWDDNGLPTERKVEKYY----GIRKDDISREEFIElcRELTDEDEKKFR--ELWRRLGLSVDWSLEYQ 144
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 105 TMDPKLSATVTEAFVRLHEEGVIYRSTRLVNWSCTLNSAISDIEVDKKELTGRtllsvpgykekvefgvLVSFAYKVQGs 184
Cdd:PRK13208 145 TISPEYRRISQKSFLDLYKKGLIYRAEAPVLWCPRCETAIAQAEVEYREREGK----------------LNYIKFPVED- 207
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 185 dsDEEVVVATTRIETMLGDVAVAVHPKDPRYQHLKGKSVVHPFLSRSLPIVFDDFVDMEFGTGAVKITPAHDQNDYEVGQ 264
Cdd:PRK13208 208 --GEEIEIATTRPELLPACVAVVVHPDDERYKHLVGKTAIVPLFGVEVPILADPLVDPDFGTGAVMICTFGDKTDVTWWR 285
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 265 RHRLEAISIMDSKGALVNVPPPFLGLPRFEARKAVLAALKEQGLFRGIKDNPMVVPLCNRSKDVVEPLLRPQWYVRCGEM 344
Cdd:PRK13208 286 ELNLPTRIIIDEDGRMTEAAGKLAGLTIEEARKKIVEDLKSGGLLGKQEPIKHNVKFCERCDTPLEILVTRQWFIKVLDL 365
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 345 AQAAsaaVTRGD-LRILPEAHQRTWHSWMDNIR-DWCISRQ--------LWW----GHRIPA----YFItvhDPA--VPP 404
Cdd:PRK13208 366 KEEL---LERGKeINWYPEHMRVRLENWIEGLNwDWCISRQryfgtpipVWYckdcGHPILPdeedLPV---DPTkdEPP 439
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 405 GEDPDGRywvsGRTEAEArekaarefgvspdkislqqDEDVLDTWFSSGLFPFSIFGWPNQSEDLSVFYPGTLLETGHDI 484
Cdd:PRK13208 440 GYKCPQC----GSPGFEG-------------------ETDVMDTWATSSITPLIVTGWERDEDLFEKVFPMDLRPQGHDI 496
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 485 LFFW----VARMVMLglklTEKLPFREVYLHAIVRDAHGRKMSKSLGNVIDPLDVIhgvslqglhdqllnsnldpsevek 560
Cdd:PRK13208 497 IRTWlfytILRAYLL----TGKLPWKNIMISGMVLDPDGKKMSKSKGNVVTPEELL------------------------ 548
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 561 akegqradfpagiPECGTDALRFGLcAYTSQGRDINLDVNRI-LGYRhFCNKLWNATKFALrGLGKGFVPSPTSKPEghe 639
Cdd:PRK13208 549 -------------EKYGADAVRYWA-ASARLGSDTPFDEKQVkIGRR-LLTKLWNASRFVL-HFSADPEPDKAEVLE--- 609
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 640 sLVDRWIRSRLAEAVRLSNEGFQAYDFPAVTTAQYSFWLYELCDVYLECLKPVL-NGVDQVAADCARQTLYTCLDVGLRL 718
Cdd:PRK13208 610 -PLDRWILAKLAKVVEKATEALENYDFAKALEEIESFFWHVFCDDYLELVKSRAyGEDEEEEQKSARYTLYTVLDTLLRL 688
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 719 LSPFMPFVTEELFQRLPRRtpnapaSLCVTPYPEPSEcSWKDPEAEAALELALSITRAVRSLRADYNLTRTRPdcfLEVA 798
Cdd:PRK13208 689 LAPFLPFITEEVWSWLYGG------SVHRASWPEPDE-ELIDEEDEELGELAKEILSAVRKYKSEAGLSLNAP---LKKV 758
|
810 820 830
....*....|....*....|....*....|....*
gi 1958756457 799 DEATGALASAVSAYVQTLASAGVVAVLALGAPAPQ 833
Cdd:PRK13208 759 EVYGPADLELLEAAEEDLKAAGNIEELELVEGDPE 793
|
|
| IleS |
COG0060 |
Isoleucyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Isoleucyl-tRNA ... |
51-808 |
4.73e-78 |
|
Isoleucyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Isoleucyl-tRNA synthetase is part of the Pathway/BioSystem: Aminoacyl-tRNA synthetases
Pssm-ID: 439830 [Multi-domain] Cd Length: 931 Bit Score: 273.49 E-value: 4.73e-78
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 51 VEKKLwkerGLNR---HQLGREAFLQE----VWKWKAEKGDriyhQLKKLGSSLDWDRACFTMDPKLSATVTEAFVRLHE 123
Cdd:COG0060 103 VEKEL----GIKKkdiEKVGIAEFREKcreyALKYVDEQRE----DFKRLGVWGDWDNPYLTMDPEYEESIWWALKKLYE 174
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 124 EGVIYRSTRLVNWSCTLNSAISDIEVdkkeltgrtllsvpGYKEKVEFGVLVSFayKVQGS-----DSDEEVVVATTRIE 198
Cdd:COG0060 175 KGLLYKGLKPVPWCPRCGTALAEAEV--------------EYKDVTSPSIYVKF--PVKDEkalllLEDAYLVIWTTTPW 238
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 199 TMLGDVAVAVHP---------KDPRY----------------------------QHLKGKSVVHPFL-----SRSLPIVF 236
Cdd:COG0060 239 TLPANLAVAVHPdidyvlvevTGGERlilaealveavlkelgiedyevlatfkgAELEGLRYEHPFYyvvgyDRAHPVIL 318
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 237 DDFVDMEFGTGAVKITPAHDQNDYEVGQRHRLEAISIMDSKGALVNVPPPFLGLPRFEARKAVLAALKEQG-LFRGIKdn 315
Cdd:COG0060 319 GDYVTTEDGTGIVHTAPGHGEDDFEVGKKYGLPVLNPVDDDGRFTEEAPLFAGLFVKDANPAIIEDLKERGaLLAREK-- 396
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 316 pmVV---PLCNRSKdvvEPLL---RPQWYVRCGEMAQAASAAVTR-------GDLRIlpeahqrtwHSWMDNIRDWCISR 382
Cdd:COG0060 397 --IThsyPHCWRCK---TPLIyraTPQWFISMDKLRDRALEAIEKvnwipewGEGRF---------GNMLENRPDWCISR 462
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 383 QLWWGHRIPAYfitVHDPavpPGEDPDGRYWVSGRTEAEAREKAAREFGVSPDKISLQQD-------------EDVLDTW 449
Cdd:COG0060 463 QRYWGVPIPIW---VCED---CGELHRTEEVIGSVAELLEEEGADAWFELDLHRPFLDETlkcpkcggtmrrvPDVLDVW 536
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 450 FSSGLFPFSIFgwpNQSEDLSvfYPGTL-LEtGHD---------ILffwvarmvmLGLKLTEKLPFREVYLHAIVRDAHG 519
Cdd:COG0060 537 FDSGSMHFAVL---ENREELH--FPADFyLE-GSDqtrgwfyssLL---------TSTALFGRAPYKNVLTHGFVLDEDG 601
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 520 RKMSKSLGNVIDPLDVIhgvslqglhDQLlnsnldpsevekakegqradfpagipecGTDALRFgLCAYTSQGRDINLDV 599
Cdd:COG0060 602 RKMSKSLGNVVDPQEVI---------DKY----------------------------GADILRL-WVASSDYWGDLRFSD 643
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 600 NRILGYRHFCNKLWNATKFALRGLGkGFVPSPTSKPEGHESLVDRWIRSRLAEAVRLSNEGFQAYDFPAVTTAqysfwLY 679
Cdd:COG0060 644 EILKEVRDVYRRLRNTYRFLLANLD-DFDPAEDAVPYEDLPELDRWILSRLNELIKEVTEAYDNYDFHRAYRA-----LH 717
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 680 ELCDV-----YLECLKPVL--NGVDQVAADCARQTLYTCLDVGLRLLSPFMPFVTEELFQRLPRrtpNAPASLCVTPYPE 752
Cdd:COG0060 718 NFCVEdlsnwYLDISKDRLytEAADSLDRRAAQTTLYEVLETLVRLLAPILPFTAEEIWQNLPG---EAEESVHLADWPE 794
|
810 820 830 840 850
....*....|....*....|....*....|....*....|....*....|....*.
gi 1958756457 753 PSEcSWKDPeaeaalelalsitravrSLRADYNLTRtrpdcflEVADEATGALASA 808
Cdd:COG0060 795 VDE-ELIDE-----------------ELEAKWDLVR-------EVRSAVLKALEAA 825
|
|
| Anticodon_Ia_Val |
cd07962 |
Anticodon-binding domain of valyl tRNA synthetases; This domain is found in valyl tRNA ... |
597-734 |
6.48e-62 |
|
Anticodon-binding domain of valyl tRNA synthetases; This domain is found in valyl tRNA synthetases (ValRS), which belong to the class Ia aminoacyl tRNA synthetases. It lies C-terminal to the catalytic core domain, and recognizes and specifically binds to the tRNA anticodon. ValRS catalyzes the transfer of valine to the 3'-end of its tRNA.
Pssm-ID: 153416 [Multi-domain] Cd Length: 135 Bit Score: 205.87 E-value: 6.48e-62
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 597 LDVNRILGYRHFCNKLWNATKFALRGLGKGFVPSPTSKPEgheSLVDRWIRSRLAEAVRLSNEGFQAYDFPAVTTAQYSF 676
Cdd:cd07962 1 FDEKRVEGGRNFCNKLWNAARFVLMNLEDDDEPEEDPESL---SLADRWILSRLNKTVEEVTEALENYRFSEAATALYEF 77
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*...
gi 1958756457 677 WLYELCDVYLECLKPVLNGVDQVAADCARQTLYTCLDVGLRLLSPFMPFVTEELFQRL 734
Cdd:cd07962 78 FWNDFCDWYLELVKPRLYGEDEEEKKAARATLYYVLETILRLLHPFMPFITEELWQRL 135
|
|
| PLN02843 |
PLN02843 |
isoleucyl-tRNA synthetase |
89-758 |
1.60e-38 |
|
isoleucyl-tRNA synthetase
Pssm-ID: 215452 [Multi-domain] Cd Length: 974 Bit Score: 155.31 E-value: 1.60e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 89 QLKKLGSSLDWDRACFTMDPKLSATVTEAFVRLHEEGVIYRSTRLVNWSCTLNSAISDIEVDKKEltgrtllsvpGYKEK 168
Cdd:PLN02843 124 SFKRYGVWGDWENPYLTLDPEYEAAQIEVFGQMFLNGYIYRGRKPVHWSPSSRTALAEAELEYPE----------GHVSK 193
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 169 VEFGVL-VSFAYKVQGSDSDE-----EVVVATTRIETMLGDVAVAVHPK------------------------------- 211
Cdd:PLN02843 194 SIYVAFpVVSPSETSPEELEEflpglSLAIWTTTPWTMPANAAVAVNDKlqysvvevqsfsedestsggnkkkrpgnvlk 273
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 212 DPRYQHL------------------------KGKSVV-----HPFLSRSLPIVFD-DFVDMEFGTGAVKITPAHDQNDYE 261
Cdd:PLN02843 274 EQQKLFLivatdlvpaleakwgvklvvlktfPGSDLEgcryiHPLYNRESPVVIGgDYITTESGTGLVHTAPGHGQEDYI 353
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 262 VGQRHRLEAISIMDSKGALVNVPPPFLGLPRF-EARKAVLAALKEQGLFrgIKDNPMV--VPLCNRSKdvvEP-LLRP-- 335
Cdd:PLN02843 354 TGLKYGLPLLSPVDDAGKFTEEAGQFSGLSVLgEGNAAVVEALDEAGSL--LMEEAYGhkYPYDWRTK---KPtIFRAte 428
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 336 QWYVRCGEMAQAASAAVtrGDLRILPEAHQRTWHSWMDNIRDWCISRQLWWGHRIPAYF------------ITVHDPAVP 403
Cdd:PLN02843 429 QWFASVEGFRQAALDAI--DKVKWIPAQGENRIRAMVSGRSDWCISRQRTWGVPIPVFYhvetkeplmneeTIAHVKSIV 506
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 404 PGEDPDGrYW---VSGRTEAEAREKAARefgvspdkisLQQDEDVLDTWFSSGlfpFSIFGWPNQSEDLSvfYPGTLLET 480
Cdd:PLN02843 507 AQKGSDA-WWymdVEDLLPEKYRDKASD----------YEKGTDTMDVWFDSG---SSWAGVLGSREGLS--YPADLYLE 570
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 481 GHDILFFWVARMVMLGLKLTEKLPFREVYLHAIVRDAHGRKMSKSLGNVIDPLDVIHGVSlqglhdqllNSNLDPSEvek 560
Cdd:PLN02843 571 GSDQHRGWFQSSLLTSVATKGKAPYKSVLTHGFVLDEKGFKMSKSLGNVVDPRLVIEGGK---------NQKQEPAY--- 638
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 561 akegqradfpagipecGTDALRFGLCA--YTSqgrDINLDVNrIL-----GYRhfcnKLWNATKFALRGLGKgFVPSPTS 633
Cdd:PLN02843 639 ----------------GADVLRLWVASvdYTG---DVLIGPQ-ILkqmsdIYR----KLRGTLRYLLGNLHD-WKPDNAV 693
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 634 KpegHESL--VDRWIRSRLAEAVRLSNEGFQAYDFPAVTTAQYSFWLYELCDVYLECLKPVL--NGVDQVAADCARQTLY 709
Cdd:PLN02843 694 P---YEDLpsIDKYALFQLENVVNEIEESYDNYQFFKIFQILQRFTIVDLSNFYLDVAKDRLyvGGTTSFTRRSCQTVLA 770
|
730 740 750 760 770
....*....|....*....|....*....|....*....|....*....|
gi 1958756457 710 TCLDVGLRLLSPFMPFVTEELFQRLPRRTPNAPA-SLCVTPYPEPSEcSW 758
Cdd:PLN02843 771 AHLLSLLRAIAPILPHLAEDAWQNLPFQEDGSAAeSVFEAGWPTPNE-EW 819
|
|
| PLN02882 |
PLN02882 |
aminoacyl-tRNA ligase |
91-755 |
3.24e-37 |
|
aminoacyl-tRNA ligase
Pssm-ID: 215477 [Multi-domain] Cd Length: 1159 Bit Score: 151.80 E-value: 3.24e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 91 KKLGSSLDWDRACFTMDPKLSATVTEAFVRLHEEGVIYRSTRLVNWSCTLNSAISDIEVDKKeltgrtllsvpgYKEKVE 170
Cdd:PLN02882 135 TRTGRWIDFENDYKTMDPKFMESVWWVFKQLFEKGLVYKGFKVMPYSTACKTPLSNFEAGLN------------YKDVSD 202
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 171 FGVLVSFAykVQGsDSDEEVVVA-TTRIETMLGDVAVAVHPK------------------DPRYQHL------------- 218
Cdd:PLN02882 203 PAVMVSFP--IVG-DPDNASFVAwTTTPWTLPSNLALCVNPNftyvkvrnkytgkvyivaESRLSALptakpkskkgskp 279
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 219 -------------KGKSVV-------HPFLSRSLPIVF----DDFVDMEFGTGAVKITPAHDQNDYEVGQRHRL-----E 269
Cdd:PLN02882 280 enaaegyevlakvPGSSLVgkkyeplFDYFSEFSDTAFrvvaDDYVTDDSGTGVVHCAPAFGEDDYRVCLANGIiekggN 359
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 270 AISIMDSKGALVNVPPPFLGLPRFEARKAVLAALKEQGlfRGIKDNPMV--VPLCNRSKdvvEPLLR---PQWYVRCGEM 344
Cdd:PLN02882 360 LPVPVDDDGCFTEKVTDFSGRYVKDADKDIIAAIKAKG--RLVKSGSIThsYPFCWRSD---TPLIYravPSWFVKVEEI 434
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 345 AQaasaavtrgdlRILPEAHQRTW----------HSWMDNIRDWCISRQLWWGHRIPAYFitvhdpavppgeDPDGRYWV 414
Cdd:PLN02882 435 KD-----------RLLENNKQTYWvpdyvkekrfHNWLENARDWAVSRSRFWGTPLPIWI------------SDDGEEVV 491
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 415 SGRTEAEARE---------------------KAAREFGVspdkisLQQDEDVLDTWFSSGLFPFSIFGWPNQSEDLsvF- 472
Cdd:PLN02882 492 VIGSIAELEKlsgvkvtdlhrhfidhitipsSRGPEFGV------LRRVDDVFDCWFESGSMPYAYIHYPFENKEL--Fe 563
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 473 --YPGTLLETGHDILFFWVARMVMLGLKLTEKLPFREVYLHAIVRDAHGRKMSKSLGNVIDPLDVIHGVSLQGLHDQLLN 550
Cdd:PLN02882 564 knFPADFVAEGLDQTRGWFYTLMVLSTALFDKPAFKNLICNGLVLAEDGKKMSKSLKNYPDPNEVIDKYGADALRLYLIN 643
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 551 SnldpsevekakegqradfpagiPECGTDALRFGLCAYTSQGRDINLD-VNrilGYRHFcnkLWNATKFALRGLGKgFVP 629
Cdd:PLN02882 644 S----------------------PVVRAEPLRFKEEGVFGVVKDVFLPwYN---AYRFL---VQNAKRLEVEGGAP-FVP 694
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 630 SPTSKPEGHESLVDRWIRSRLAEAVRLSNEGFQAYDFPAVTTAQYSFwLYELCDVYLECLKPVLNGVDQVA-ADCARQTL 708
Cdd:PLN02882 695 LDLAKLQNSANVLDRWINSATQSLVKFVREEMGAYRLYTVVPYLVKF-IDNLTNIYVRFNRKRLKGRTGEEdCRTALSTL 773
|
730 740 750 760
....*....|....*....|....*....|....*....|....*..
gi 1958756457 709 YTCLDVGLRLLSPFMPFVTEELFQRLPRRTPNAPASLCVTPYPEPSE 755
Cdd:PLN02882 774 YNVLLTSCKVMAPFTPFFTEVLYQNLRKVLPGSEESIHYCSFPQVDE 820
|
|
| Ile_Leu_Val_MetRS_core |
cd00668 |
catalytic core domain of isoleucyl, leucyl, valyl and methioninyl tRNA synthetases; Catalytic ... |
335-536 |
7.80e-36 |
|
catalytic core domain of isoleucyl, leucyl, valyl and methioninyl tRNA synthetases; Catalytic core domain of isoleucyl, leucyl, valyl and methioninyl tRNA synthetases. These class I enzymes are all monomers. However, in some species, MetRS functions as a homodimer, as a result of an additional C-terminal domain. These enzymes aminoacylate the 2'-OH of the nucleotide at the 3' of the appropriate tRNA. The core domain is based on the Rossman fold and is responsible for the ATP-dependent formation of the enzyme bound aminoacyl-adenylate. It contains the characteristic class I HIGH and KMSKS motifs, which are involved in ATP binding. Enzymes in this subfamily share an insertion in the core domain, which is subject to both deletions and rearrangements. This editing region hydrolyzes mischarged cognate tRNAs and thus prevents the incorporation of chemically similar amino acids. MetRS has a significantly shorter insertion, which lacks the editing function.
Pssm-ID: 185674 [Multi-domain] Cd Length: 312 Bit Score: 138.32 E-value: 7.80e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 335 PQWYVRCGEMAQAASAAVTRGDlrILPEAHQRTWHSWMDNIRDWCISRQLWWGHRIPayfitvhdpavppgedpdgrywv 414
Cdd:cd00668 140 EQWFFDMPKFKEKLLKALRRGK--IVPEHVKNRMEAWLESLLDWAISRQRYWGTPLP----------------------- 194
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 415 sgrteaearekaarefgvspdkislqqdEDVLDTWFSSGLFPFSIFGWPNQSEDLSVFYPGTLLETGHDILFFWVARMVM 494
Cdd:cd00668 195 ----------------------------EDVFDVWFDSGIGPLGSLGYPEEKEWFKDSYPADWHLIGKDILRGWANFWIT 246
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 1958756457 495 LGLKLTEKLPFREVYLHAIVRDAHGRKMSKSLGNVIDPLDVI 536
Cdd:cd00668 247 MLVALFGEIPPKNLLVHGFVLDEGGQKMSKSKGNVIDPSDVV 288
|
|
| Anticodon_1 |
pfam08264 |
Anticodon-binding domain of tRNA ligase; This domain is found mainly hydrophobic tRNA ... |
643-786 |
6.46e-30 |
|
Anticodon-binding domain of tRNA ligase; This domain is found mainly hydrophobic tRNA synthetases. The domain binds to the anticodon of the tRNA ligase.
Pssm-ID: 400523 [Multi-domain] Cd Length: 141 Bit Score: 115.58 E-value: 6.46e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 643 DRWIRSRLAEAVRLSNEGFQAYDFPAVTTAQYSFWLYELCDVYLECLKPVLNGVDqvAADCARQTLYTCLDVGLRLLSPF 722
Cdd:pfam08264 1 DRWILSRLNKLIKEVTEAYENYRFNTAAQALYEFFWNDLSDWYLELIKDRLYGEE--PDSRAQTTLYEVLETLLRLLAPF 78
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1958756457 723 MPFVTEELFQRLprrtpnapaSLCVTPYPEPSECSwkDPEAEAALELALSITRAVRSLRADYNL 786
Cdd:pfam08264 79 MPFITEELWQKE---------SIHLAPWPEDAELE--EAELEEAFELRQEIVQAIRKLRSELKI 131
|
|
| PTZ00427 |
PTZ00427 |
isoleucine-tRNA ligase, putative; Provisional |
90-736 |
9.82e-30 |
|
isoleucine-tRNA ligase, putative; Provisional
Pssm-ID: 173617 [Multi-domain] Cd Length: 1205 Bit Score: 127.78 E-value: 9.82e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 90 LKKLGSSLDWDRACFTMDPKLSATVTEAFVRLHEEGVIYRSTRLVNWSCTLNSAISDIEV-------------------- 149
Cdd:PTZ00427 198 VERIGRWIDFKNDYKTMDKTFMESVWWVFSELYKNNYVYKSFKVMPYSCKCNTPISNFELnlnykdtpdpsiiisfvlcs 277
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 150 ------------DKKELTGRTLlsVPGYKEKVEFG------------------------------------VLVSFAY-K 180
Cdd:PTZ00427 278 dfpkveeecnieEDKQLLGEKY--SVLYNNKRENSnngnnnstnnvcyaqhseilawtttpwtlpsnlalcVNEHFTYlR 355
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 181 VQGSDSDEEVVVATTRIETMLGDVAVAV------------HPKDPRYQHLKGKSV-VHPFLSRSLPIVFDDFVDMEFGTG 247
Cdd:PTZ00427 356 IHHVKSNRVVIVGECRLEWIMKELKWNVedlkivnrfkgkELKGLRYKPLFTNFYeKYNFKERAYKILADDFVTDDAGTG 435
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 248 AVKITPAHDQNDYEVGQRHRL----EAISI--MDSKGALVNVPPPFLGLPRFEARKAVLAALKEQGlfRGIKDNPMV--V 319
Cdd:PTZ00427 436 IVHCAPTYGEDDFRVCKKNGVidpeKNIFIdpLDANGYFTNEVEEVQNLYIKEADNVIKKKLKNEN--RLLSNNTIVhsY 513
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 320 PLCNRSKdvvEPLLR---PQWYVRcgeMAQAASAAVTRGDLRILPEAH--QRTWHSWMDNIRDWCISRQLWWGHRIPAY- 393
Cdd:PTZ00427 514 PFCWRSD---TPLIYraiPAWFIR---VSNSTNELVKNNETTYWIPAHikEKKFHNWIKDAKDWCISRNRYWGTPIPIWa 587
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 394 ------FITVHdpAVPPGEDPDG--------RYWVSgrtEAEAREKAAREFGvspdkiSLQQDEDVLDTWFSSGLFPFSI 459
Cdd:PTZ00427 588 dekmetVICVE--SIKHLEELSGvknindlhRHFID---HIEIKNPKGKTYP------KLKRIPEVFDCWFESGSMPYAK 656
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 460 FGWP--NQSEDLSVFYPGTLLETGHDILFFWVARMVMLGLKLTEKLPFREVYLHAIVRDAHGRKMSKSLGNVIDPLDVIH 537
Cdd:PTZ00427 657 VHYPfsTEKEDFHKIFPADFIAEGLDQTRGWFYTLLVISTLLFDKAPFKNLICNGLVLASDGKKMSKRLKNYPDPLYILD 736
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 538 GVSLQGLHDQLLNSNLDPSEVEKAKEgqradfpAGIPEcgtdALRFGLCAYTSQGRDINLDVNRIlgyrhfcnKLWNATK 617
Cdd:PTZ00427 737 KYGADSLRLYLINSVAVRAENLKFQE-------KGVNE----VVKSFILPFYHSFRFFSQEVTRY--------ECLNKKQ 797
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 618 FALRglgkgfvpspTSKPEGHESLVDRWIRSRLAEAVRLSNEGFQAYDFPAVTTAQYSFwLYELCDVYLECLKPVLNGVd 697
Cdd:PTZ00427 798 FLFN----------TDYIYKNDNIMDQWIFSSVQSLTKSVHTEMKAYKLYNVLPKLLQF-IENLTNWYIRLNRDRMRGS- 865
|
730 740 750 760
....*....|....*....|....*....|....*....|.
gi 1958756457 698 QVAADCARQ--TLYTCLDVGLRLLSPFMPFVTEELFQRLPR 736
Cdd:PTZ00427 866 LGEENCLQSlcTTYRTLHLFTVLMAPFTPFITEYIYQQLRR 906
|
|
| IleRS_core |
cd00818 |
catalytic core domain of isoleucyl-tRNA synthetases; Isoleucine amino-acyl tRNA synthetases ... |
291-537 |
2.61e-28 |
|
catalytic core domain of isoleucyl-tRNA synthetases; Isoleucine amino-acyl tRNA synthetases (IleRS) catalytic core domain . This class I enzyme is a monomer which aminoacylates the 2'-OH of the nucleotide at the 3' of the appropriate tRNA. The core domain is based on the Rossman fold and is responsible for the ATP-dependent formation of the enzyme bound aminoacyl-adenylate. It contains the characteristic class I HIGH and KMSKS motifs, which are involved in ATP binding. IleRS has an insertion in the core domain, which is subject to both deletions and rearrangements. This editing region hydrolyzes mischarged cognate tRNAs and thus prevents the incorporation of chemically similar amino acids.
Pssm-ID: 173909 [Multi-domain] Cd Length: 338 Bit Score: 116.95 E-value: 2.61e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 291 PRFEArkAVLAALKE---QGL-FRGIKdnPMVVPLCNRSKdvvepllrPQWYVRCGEMAQAASAAVTRgdLRILPEAHQR 366
Cdd:cd00818 115 PEYME--SVWWVFKQlheKGLlYRGYK--VVPWPLIYRAT--------PQWFIRVTKIKDRLLEANDK--VNWIPEWVKN 180
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 367 TWHSWMDNIRDWCISRQLWWGHRIPAyfitvhdpavppgedpdgryWVSgrteaearekaarefgVSPDKISLQQDEDVL 446
Cdd:cd00818 181 RFGNWLENRRDWCISRQRYWGTPIPV--------------------WYC----------------EDCGEVLVRRVPDVL 224
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 447 DTWFSSGLFPFSIFGWPNQSEDLSVFYPGTLLETGHDILFFWVARMVMLGLKLTEKLPFREVYLHAIVRDAHGRKMSKSL 526
Cdd:cd00818 225 DVWFDSGSMPYAQLHYPFENEDFEELFPADFILEGSDQTRGWFYSLLLLSTALFGKAPYKNVIVHGFVLDEDGRKMSKSL 304
|
250
....*....|.
gi 1958756457 527 GNVIDPLDVIH 537
Cdd:cd00818 305 GNYVDPQEVVD 315
|
|
| leuS_bact |
TIGR00396 |
leucyl-tRNA synthetase, eubacterial and mitochondrial family; The leucyl-tRNA synthetases ... |
77-734 |
2.79e-24 |
|
leucyl-tRNA synthetase, eubacterial and mitochondrial family; The leucyl-tRNA synthetases belong to two families so broadly different that they are represented by separate models. This model includes both eubacterial and mitochondrial leucyl-tRNA synthetases. It generates higher scores for some valyl-tRNA synthetases than for any archaeal or eukaryotic cytosolic leucyl-tRNA synthetase. Note that the enzyme from Aquifex aeolicus is split into alpha and beta chains; neither chain is long enough to score above the trusted cutoff, but the alpha chain scores well above the noise cutoff. The beta chain must be found by a model and search designed for partial length matches. [Protein synthesis, tRNA aminoacylation]
Pssm-ID: 273057 [Multi-domain] Cd Length: 842 Bit Score: 109.46 E-value: 2.79e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 77 KWKAEKGDRIYHQLKKLGSSLDWDRACFTMDPKLSATVTEAFVRLHEEGVIYRSTRLVNWSCTLNSAI------------ 144
Cdd:TIGR00396 95 KWTYENIANMKKQLQALGFSYDWDREIATCDPEYYKWTQWIFLELFEKGLAYVKEADVNWCPNDGTVLaneqvdsdgrsw 174
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 145 -SDIEVDKKELTgRTLLSVPGYKEKV------------------------EFGVLVSFAYKvqgsDSDEEVVVATTRIET 199
Cdd:TIGR00396 175 rGDTPVEKKELK-QWFLKITAYAEELlndleeldhwpesvkemqrnwigkSEGVEITFKIA----DHDEKITVFTTRPDT 249
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 200 MLGDVAVAVHPKDPRYQH---------------------------------LKGKSVVHPFLSRSLPIVFDDFVDMEFGT 246
Cdd:TIGR00396 250 IFGVTYLALAPEHPLVEKaaennpkvaafikkilnktvaertkatkekkgvDTGIKAIHPLTGEKIPIWVANYVLMEYGT 329
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 247 GAVKITPAHDQNDYEVGQRHRLEAISIMDS-------------KGALVNvPPPFLGLPRFEARKAVLAALKEQGLfrgik 313
Cdd:TIGR00396 330 GAVMGVPAHDERDFEFAQKYGLPIKPVIDPaekdlsltaayteDGVLVN-SGEFNGLNSSEARNAIIDMLEKEGK----- 403
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 314 dnpmvvplcnrSKDVVEpllrpqwYvrcgemaqaasaavtrgdlrilpeahqrtwhswmdNIRDWCISRQLWWGHRIPAY 393
Cdd:TIGR00396 404 -----------GKRKVN-------Y-----------------------------------RLRDWGFSRQRYWGEPIPII 430
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 394 FITVHDPAVPPGED------------PDG-------RYWVSgRTEAEAREKAAREfgvspdkislqqdEDVLDTWFSSG- 453
Cdd:TIGR00396 431 HCEDGGVVPVPEEDlpvilpedvvydGDGgsplsriPEWVN-VTCPSCGKPALRE-------------TDTMDTFAGSSw 496
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 454 -LFPFSIFGWPNQSED---LSVFYPGTLLETG--HDILF-----FWVARMVMLGLkLTEKLPFREVYLHAIV-------- 514
Cdd:TIGR00396 497 yYLRYLDPKNTDGPFDkekAEYWLPVDLYIGGieHAILHllyarFFHKFLRDIGY-VNTKEPFKKLINQGMVlgfyyppn 575
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 515 ---------------RDAHGR--------KMSKSLGNVIDPLDVIHgvslqglhdqllnsnldpsevekakegqradfpa 571
Cdd:TIGR00396 576 gkvpadvlterdekgKDKAGGelvyvgyeKMSKSKGNGIDPQEIVE---------------------------------- 621
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 572 gipECGTDALRFGLCAYTSQGRDINLDVNRILGYRHFCNKLWNatkFALRGLGKGFVPSPTSKPeghESLVDRWIRSRLA 651
Cdd:TIGR00396 622 ---SYGADALRLFIMFMGPIAASLEWNESGLEGARRFLDRVWN---LVYEITGELDAASLTVTA---LEEAQKELRRDVH 692
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 652 EAVRLSNEGFQ-AYDFPAVTTAQYSF----WLYELCDVYLECLKPVlngvdqvaadcarqtlytcldvgLRLLSPFMPFV 726
Cdd:TIGR00396 693 KFLKKVTEDLEkRESFNTAISAMMELlnklYKAKKEALMLEYLKGF-----------------------VTVLSPFAPHL 749
|
....*...
gi 1958756457 727 TEELFQRL 734
Cdd:TIGR00396 750 AEELWEKL 757
|
|
| LeuS |
COG0495 |
Leucyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Leucyl-tRNA ... |
89-536 |
1.51e-21 |
|
Leucyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Leucyl-tRNA synthetase is part of the Pathway/BioSystem: Aminoacyl-tRNA synthetases
Pssm-ID: 440261 [Multi-domain] Cd Length: 826 Bit Score: 100.90 E-value: 1.51e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 89 QLKKLGSSLDWDRACFTMDP-------KLsatvteaFVRLHEEGVIYRSTRLVNWSCTLN------------SAISDIEV 149
Cdd:COG0495 111 QLKRLGLSYDWSREIATCDPeyykwtqWI-------FLQLYEKGLAYRKEAPVNWCPVDQtvlaneqvidgrCWRCGAPV 183
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 150 DKKELTG----------RtLLS----VPGYKEKV----------EFGVLVSFAYKvqgsDSDEEVVVATTRIETMLGD-- 203
Cdd:COG0495 184 EKKELPQwflkitdyadE-LLDdldkLDGWPEKVktmqrnwigrSEGAEVDFPVE----GSDEKITVFTTRPDTLFGAtf 258
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 204 VAVAV-HP------KDPRYQHLK--------------------------GKSVVHPFLSRSLPIVFDDFVDMEFGTGAVK 250
Cdd:COG0495 259 MVLAPeHPlvkelaTPEQNAAVAafieeakkkseiertsetkektgvftGLYAINPLTGEKIPIWIADYVLMDYGTGAVM 338
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 251 ITPAHDQNDYEVGQRHRL-----------EAISIMDS----KGALVNvPPPFLGLPRFEARKAVLAALKEQGLfrgikdn 315
Cdd:COG0495 339 AVPAHDQRDFEFAKKYGLpikqviapedgDDPDILEEaytgDGVLIN-SGEFDGLDSEEAKEAIIEWLEEKGL------- 410
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 316 pmvvplcnrskdvvepllrpqwyvrcGEmaqaasAAVT-RgdlrilpeahqrtwhswmdnIRDWCISRQLWWGHRIPAyf 394
Cdd:COG0495 411 --------------------------GK------RKVNyR--------------------LRDWLISRQRYWGEPIPI-- 436
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 395 itVHDP-----AVP----------------PGEDPDGRY--WVS------GRteaeareKAAREFgvspdkislqqdeDV 445
Cdd:COG0495 437 --IHCEdcgvvPVPedqlpvelpedvdfdpTGGSPLARApeWVNvtcpkcGG-------PARRET-------------DT 494
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 446 LDTWF-SSglfpfsifgW-------PNQSE--------------DLsvfYPGtlletG--HDIL------FFWvarMVM- 494
Cdd:COG0495 495 MDTFVdSS---------WyylrytdPHNDEapfdpeaanywlpvDQ---YIG-----GieHAILhllyarFFT---KVLr 554
|
570 580 590 600 610
....*....|....*....|....*....|....*....|....*....|...
gi 1958756457 495 -LGL-KLTEklPFR---------EVYLHAIVRDAHGrKMSKSLGNVIDPLDVI 536
Cdd:COG0495 555 dLGLvSFDE--PFKrlltqgmvlEVGKDGVVIGGIE-KMSKSKGNVVDPDEII 604
|
|
| leuS |
PRK12300 |
leucyl-tRNA synthetase; Reviewed |
90-761 |
1.77e-20 |
|
leucyl-tRNA synthetase; Reviewed
Pssm-ID: 237049 [Multi-domain] Cd Length: 897 Bit Score: 97.25 E-value: 1.77e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 90 LKKLGSSLDWDRACFTMDPKLSATVTEAFVRLHEEGVIYRSTRLVNWSCTLNSAISDieVDKKELTGrtllsvpgyKEKV 169
Cdd:PRK12300 89 MKRIGYSIDWRREFTTTDPEYSKFIEWQFRKLKEKGLIVKGSHPVRYCPNDNNPVGD--HDLLDGEE---------PEIV 157
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 170 EFgVLVSFAykvqgsDSDEEV-VVATTRIETMLGDVAVAVHPKDP---------------------RYQH---------- 217
Cdd:PRK12300 158 EY-TLIKFE------ESEDLIlPAATLRPETIFGVTNLWVNPDATyvkaevdgekwivskeaaeklSFQDrdveiieeik 230
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 218 ---LKGKSVVHPFLSRSLPIVFDDFVDMEFGTGAVKITPAHDQNDY----EVGQRHRL----EAISIMD----------- 275
Cdd:PRK12300 231 gseLIGKKVKNPVTGKEVPILPADFVDPDNGTGVVMSVPAHAPYDYvalrDLKKNKELldviEPIPLIEvegygefpake 310
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 276 ---------------------------SKGALVNVPPPFLGLPRFEARKAVLAALKEQGLfrGIK----DNPMVVPLCNr 324
Cdd:PRK12300 311 vveklgiksqedpeleeatkevyraefHKGVLKENTGEYAGKPVREAREKITKDLIEKGI--ADImyefSNRPVYCRCG- 387
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 325 SKDVVEpLLRPQWYVRCGEMAQAASA--AVTRgdLRILPEAHQRTWHSWMDNIRDWCISRQLWWGHRIP----------- 391
Cdd:PRK12300 388 TECVVK-VVKDQWFIDYSDPEWKELAhkALDN--MEIIPEEYRKEFENTIDWLKDRACARRRGLGTRLPwdeewiiesls 464
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 392 ------AYFITVHdpavppgedpdgrywvsgrteaearekAAREFGVSPDKIslqqDEDVLDTWFSSGLFPFSIF---GW 462
Cdd:PRK12300 465 dstiymAYYTIAH---------------------------KIREYGIKPEQL----TPEFFDYVFLGKGDPEEVSkktGI 513
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 463 PNQ-----SEDLSVFYPGTLLETGHD-----ILFF------------WVARMVMLGLKLTEklpfrevylhaivrdahGR 520
Cdd:PRK12300 514 PKEileemREEFLYWYPVDWRHSGKDlipnhLTFFifnhvaifpeekWPRGIVVNGFVLLE-----------------GK 576
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 521 KMSKSLGNVIdPLdvihgvslqglhdqllnsnldpsevEKAKEgqradfpagipECGTDALRFGLCAYTSQGRDINLDVN 600
Cdd:PRK12300 577 KMSKSKGNVI-PL-------------------------RKAIE-----------EYGADVVRLYLTSSAELLQDADWREK 619
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 601 RILGYRHFCNKLWNatkFALRGLGKGfvpsptskPEGHESLVDRWIRSRLAEAVRLSNEGFQAYDF-PAVTTAQYSfwLY 679
Cdd:PRK12300 620 EVESVRRQLERFYE---LAKELIEIG--------GEEELRFIDKWLLSRLNRIIKETTEAMESFQTrDAVQEAFYE--LL 686
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 680 ELCDVYLEcLKPVLNgvdqvaadcaRQTLYTCLDVGLRLLSPFMPFVTEELFQRLPRRTpnaPASLcvTPYPEPSEcSWK 759
Cdd:PRK12300 687 NDLRWYLR-RVGEAN----------NKVLREVLEIWIRLLAPFTPHLAEELWHKLGGEG---FVSL--EKWPEPDE-SKI 749
|
..
gi 1958756457 760 DP 761
Cdd:PRK12300 750 DE 751
|
|
| Anticodon_Ia_Ile_ABEc |
cd07961 |
Anticodon-binding domain of archaeal, bacterial, and eukaryotic cytoplasmic isoleucyl tRNA ... |
606-755 |
3.67e-18 |
|
Anticodon-binding domain of archaeal, bacterial, and eukaryotic cytoplasmic isoleucyl tRNA synthetases; This domain is found in isoleucyl tRNA synthetases (IleRS), which belong to the class Ia aminoacyl tRNA synthetases. It lies C-terminal to the catalytic core domain, and recognizes and specifically binds to the tRNA anticodon. This family includes bacterial, archaeal, and eukaryotic cytoplasmic members. IleRS catalyzes the transfer of isoleucine to the 3'-end of its tRNA.
Pssm-ID: 153415 [Multi-domain] Cd Length: 183 Bit Score: 83.37 E-value: 3.67e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 606 RHFCNKLWNATKFAL--RGLgKGFVPSPTSKPEGHESLVDRWIRSRLAEAVRLSNEGFQAYDFPAVTTAQYSFWLyELCD 683
Cdd:cd07961 11 RKVLLPLWNAYRFFVtyANL-DGFDPGKDDDAVASLNVLDRWILSRLNSLIKEVTEEMEAYDLYTAVRALLEFID-ELTN 88
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1958756457 684 VYL----ECLKPVLNGVDQVAAdcaRQTLYTCLDVGLRLLSPFMPFVTEELFQRLPRRTPNAPASLCVTPYPEPSE 755
Cdd:cd07961 89 WYIrrnrKRFWGEEGDDDKLAA---YATLYEVLLTLSRLMAPFTPFITEEIYQNLRRELGDAPESVHLLDWPEVDE 161
|
|
| PLN02563 |
PLN02563 |
aminoacyl-tRNA ligase |
46-407 |
1.84e-16 |
|
aminoacyl-tRNA ligase
Pssm-ID: 178177 [Multi-domain] Cd Length: 963 Bit Score: 84.49 E-value: 1.84e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 46 ATQVVveKKLWKERGLN-RHQLGREAFLQEVWKWKAEKG-----------DRIYHQLKKLGSSLDWDRACFTMDPKLSAT 113
Cdd:PLN02563 136 ATDIL--ARYKRMQGYNvLHPMGWDAFGLPAEQYAIETGthpkittlkniARFRSQLKSLGFSYDWDREISTTEPEYYKW 213
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 114 VTEAFVRLHEEGVIYRSTRLVNWSCTLNSAISDIEVDK--KELTGRTLLSVP--------------------------GY 165
Cdd:PLN02563 214 TQWIFLQLLKRGLAYQAEVPVNWCPALGTVLANEEVVDglSERGGHPVIRKPmrqwmlkitayadrlledlddldwpeSI 293
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 166 KE------------KVEFGVLvsfayKVQGSDSDEEVVVATTRIETMLGDVAVAVHPKDP-------------------- 213
Cdd:PLN02563 294 KEmqrnwigrsegaELDFSVL-----DGEGKERDEKITVYTTRPDTLFGATYLVVAPEHPllsslttaeqkeaveeyvda 368
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 214 --------RYQHLKGKSVV-------HPFLSRSLPIVFDDFVDMEFGTGAVKITPAHDQNDYEVGQRHRLEAISIMDS-- 276
Cdd:PLN02563 369 asrksdleRTELQKEKTGVftgsyaiNPATGEAIPIWVADYVLGSYGTGAIMAVPAHDTRDFEFAQKFDLPIKWVVKPad 448
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 277 ------------KGALVNVPPPFL---GLPRFEARKAVLAALKEQGlfrgikdnpmvvplcNRSKDVVEPLlrpqwyvrc 341
Cdd:PLN02563 449 gneddaekaytgEGVIVNSSSSGLdinGLSSKEAAKKVIEWLEETG---------------NGKKKVNYKL--------- 504
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1958756457 342 gemaqaasaavtrgdlrilpeahqrtwhswmdniRDWCISRQLWWGHRIPAYFITVHDPAVPPGED 407
Cdd:PLN02563 505 ----------------------------------RDWLFARQRYWGEPIPVVFLEDSGEPVPVPES 536
|
|
| Anticodon_Ia_Ile_BEm |
cd07960 |
Anticodon-binding domain of bacterial and eukaryotic mitochondrial isoleucyl tRNA synthetases; ... |
605-761 |
2.31e-13 |
|
Anticodon-binding domain of bacterial and eukaryotic mitochondrial isoleucyl tRNA synthetases; This domain is found in isoleucyl tRNA synthetases (IleRS), which belong to the class Ia aminoacyl tRNA synthetases. It lies C-terminal to the catalytic core domain, and recognizes and specifically binds to the tRNA anticodon. This family includes bacterial and eukaryotic mitochondrial members. IleRS catalyzes the transfer of isoleucine to the 3'-end of its tRNA.
Pssm-ID: 153414 [Multi-domain] Cd Length: 180 Bit Score: 69.09 E-value: 2.31e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 605 YRhfcnKLWNATKFALRGLGkGFVPSPTSKPEGHESLVDRWIRSRLAEAVRLSNEGFQAYDFPAVTTAQYSFWLYELCDV 684
Cdd:cd07960 13 YR----KIRNTFRFLLGNLN-DFDPAKDAVPYEELLELDRYALHRLNELIKEVREAYENYEFHKVYQALNNFCTVDLSAF 87
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1958756457 685 YLECLKPVL--NGVDQVAADCARQTLYTCLDVGLRLLSPFMPFVTEELFQRLPRRTPNAPASLcvTPYPEPSEcSWKDP 761
Cdd:cd07960 88 YLDIIKDRLycDAKDSLERRSAQTVLYHILDALLKLLAPILPFTAEEVWEHLPGEKKEESVFL--EDWPELPE-EWKDE 163
|
|
| MetG |
COG0143 |
Methionyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Methionyl-tRNA ... |
370-734 |
7.42e-12 |
|
Methionyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Methionyl-tRNA synthetase is part of the Pathway/BioSystem: Aminoacyl-tRNA synthetases
Pssm-ID: 439913 [Multi-domain] Cd Length: 544 Bit Score: 68.99 E-value: 7.42e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 370 SWMDN-IRDWCISRQLWWGhrIPayfitvhdpaVPpgEDPDGRYWVsgrteaearekaarefgvspdkislqqdedvldt 448
Cdd:COG0143 217 SWLKEgLQDLSISRDFDWG--IP----------VP--GDPGKVFYV---------------------------------- 248
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 449 WF-------SSglfpfsIFGWP---NQSEDLSVFYPGTLLETGH----DILFF----WVArMVM-LGLKLTEKLPfrevy 509
Cdd:COG0143 249 WFdaligyiSA------TKGYAddrGLPEDFEKYWPAPDTELVHfigkDIIRFhaiiWPA-MLMaAGLPLPKKVF----- 316
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 510 lhaivrdAH------GRKMSKSLGNVIDPLDVIhgvslqglhdqllnsnldpsevekakegqrADFPAgipecgtDALRF 583
Cdd:COG0143 317 -------AHgfltveGEKMSKSRGNVIDPDDLL------------------------------DRYGP-------DALRY 352
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 584 GLCAYTSQGRDINLD-------------------VNRILGyrhFCNKLWNatkfalrglgkGFVPSPtskpeGHESLVDR 644
Cdd:COG0143 353 YLLREVPFGQDGDFSwedfvarvnsdlandlgnlASRTLS---MIHKYFD-----------GKVPEP-----GELTEADE 413
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 645 WIRSRLAEAVRLSNEGFQAYDFPAVTTAqysfwLYELCDV---YLECLKP-VLNGVDQVAAdcARQTLYTCLDVgLR--- 717
Cdd:COG0143 414 ELLAEAEAALEEVAEAMEAFEFRKALEE-----IMALARAankYIDETAPwKLAKDEDPER--LATVLYTLLEA-LRila 485
|
410
....*....|....*...
gi 1958756457 718 -LLSPFMPFVTEELFQRL 734
Cdd:COG0143 486 iLLKPFLPETAEKILEQL 503
|
|
| tRNA-synt_1_2 |
pfam13603 |
Leucyl-tRNA synthetase, Domain 2; This is a family of the conserved region of Leucine-tRNA ... |
172-299 |
8.20e-12 |
|
Leucyl-tRNA synthetase, Domain 2; This is a family of the conserved region of Leucine-tRNA ligase or Leucyl-tRNA synthetase, EC:6.1.1.4.
Pssm-ID: 433342 [Multi-domain] Cd Length: 185 Bit Score: 64.88 E-value: 8.20e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 172 GVLVSFAYKvqgsDSDEEVVVATTRIETMLGD--VAVAV-HP-------KDP-------RYQHLK--------------- 219
Cdd:pfam13603 9 GAEITFPVE----GTDEKIEVFTTRPDTLMGVtfVALAPeHPlveklaeKNPevaafieECKNTSeiertsetkekegvf 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 220 -GKSVVHPFLSRSLPIVFDDFVDMEFGTGAVKITPAHDQNDYEVGQRHRL------------EAISIMDS----KGALVN 282
Cdd:pfam13603 85 tGLYAIHPITGEKIPIWIANFVLMEYGTGAVMAVPAHDQRDFEFAKKYNLpikpviqpedgdLDLDIMTEayteEGILVN 164
|
170
....*....|....*..
gi 1958756457 283 vPPPFLGLPRFEARKAV 299
Cdd:pfam13603 165 -SGEFDGLDSEEAKEAI 180
|
|
| Anticodon_Ia_like |
cd07375 |
Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; This ... |
600-723 |
1.91e-08 |
|
Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; This domain is found in a variety of class Ia aminoacyl tRNA synthetases, C-terminal to the catalytic core domain. It recognizes and specifically binds to the anticodon of the tRNA. Aminoacyl tRNA synthetases catalyze the transfer of cognate amino acids to the 3'-end of their tRNAs by specifically recognizing cognate from non-cognate amino acids. Members include valyl-, leucyl-, isoleucyl-, cysteinyl-, arginyl-, and methionyl-tRNA synthethases. This superfamily also includes a domain from MshC, an enzyme in the mycothiol biosynthetic pathway.
Pssm-ID: 153408 [Multi-domain] Cd Length: 117 Bit Score: 53.28 E-value: 1.91e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 600 NRILGYRHFCNKLWNATKFALRGLGKGFVPSPTSKPEGheslVDRWIRSRLAEAVRLSNEGFQAYDFPAVTTAQYSFWLY 679
Cdd:cd07375 2 ERLKQARAFLNRLYRLLSFFRKALGGTQPKWDNELLEE----ADRELLARLQEFIKRTTNALEALDPTTAVQELFKFTNE 77
|
90 100 110 120
....*....|....*....|....*....|....*....|....
gi 1958756457 680 ElcDVYLECLKPVLNGVDQVAAdcARQTLYTCLDVGLRLLSPFM 723
Cdd:cd07375 78 L--NWYLDELKPALQTEELREA--VLAVLRAALVVLTKLLAPFT 117
|
|
| PRK11893 |
PRK11893 |
methionyl-tRNA synthetase; Reviewed |
437-734 |
4.16e-07 |
|
methionyl-tRNA synthetase; Reviewed
Pssm-ID: 237012 [Multi-domain] Cd Length: 511 Bit Score: 53.73 E-value: 4.16e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 437 ISLQQDED-VLDTWFSsGLFPF-SIFGWPNQSEDLSV----FYPGTLLETGHDILFF----WVARMVMLGLKLTEKlpfr 506
Cdd:PRK11893 212 IPVPGDPKhVIYVWFD-ALTNYlTALGYPDDEELLAElfnkYWPADVHLIGKDILRFhavyWPAFLMAAGLPLPKR---- 286
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 507 eVYLHA-IVRDahGRKMSKSLGNVIDPLDVIHgvslqglhdqllnsnldpsevekakegqradfpagipECGTDALRFGL 585
Cdd:PRK11893 287 -VFAHGfLTLD--GEKMSKSLGNVIDPFDLVD-------------------------------------EYGVDAVRYFL 326
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 586 CAYTSQGRDINLDVNRILGYR--HFCNKLWN---ATKFALRGLGKGFVPSPTSKPEGHESLVDrwirsRLAEAVRLSNEG 660
Cdd:PRK11893 327 LREIPFGQDGDFSREAFINRInaDLANDLGNlaqRTLSMIAKNFDGKVPEPGALTEADEALLE-----AAAALLERVRAA 401
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 661 FQAYDFpavTTAQYSFW-LYELCDVYLECLKPVLngvdQVAADCAR--QTLYTCLDvGLR----LLSPFMPFVTEELFQR 733
Cdd:PRK11893 402 MDNLAF---DKALEAILaLVRAANKYIDEQAPWS----LAKTDPERlaTVLYTLLE-VLRgiavLLQPVMPELAAKILDQ 473
|
.
gi 1958756457 734 L 734
Cdd:PRK11893 474 L 474
|
|
| Anticodon_Ia_Leu_AEc |
cd07959 |
Anticodon-binding domain of archaeal and eukaryotic cytoplasmic leucyl tRNA synthetases; This ... |
630-734 |
4.84e-07 |
|
Anticodon-binding domain of archaeal and eukaryotic cytoplasmic leucyl tRNA synthetases; This domain is found in leucyl tRNA synthetases (LeuRS), which belong to the class Ia aminoacyl tRNA synthetases. It lies C-terminal to the catalytic core domain. In contrast to other class Ia enzymes, the anticodon is not used as an identity element in LeuRS (with exceptions such as Saccharomyces cerevisiae and some other eukaryotes). No anticodon-binding site can be defined for this family, which includes archaeal and eukaryotic cytoplasmic members. LeuRS catalyzes the transfer of leucine to the 3'-end of its tRNA.
Pssm-ID: 153413 [Multi-domain] Cd Length: 117 Bit Score: 49.13 E-value: 4.84e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 630 SPTSKPEGHESLVDRWIRSRLAEAVRLSNEGFQAYDF-PAVTTAQYSFwlYELCDVYLEclkpvlngvdQVAADCARQTL 708
Cdd:cd07959 24 IETEGELEELTFIDRWLLSRLNRLIKETTEAYENMQFrEALKEGLYEL--QNDLDWYRE----------RGGAGMNKDLL 91
|
90 100
....*....|....*....|....*.
gi 1958756457 709 YTCLDVGLRLLSPFMPFVTEELFQRL 734
Cdd:cd07959 92 RRFIEVWTRLLAPFAPHLAEEIWHEL 117
|
|
| PRK12267 |
PRK12267 |
methionyl-tRNA synthetase; Reviewed |
461-536 |
1.31e-06 |
|
methionyl-tRNA synthetase; Reviewed
Pssm-ID: 237028 [Multi-domain] Cd Length: 648 Bit Score: 52.11 E-value: 1.31e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 461 GWPNQSEDLS-VFYPGTLLETGHDIL-F---FWVARMVMLGLKLteklpFREVYLHA-IVRDahGRKMSKSLGNVIDPLD 534
Cdd:PRK12267 240 GYGSDDDELFkKFWPADVHLVGKDILrFhaiYWPIMLMALGLPL-----PKKVFAHGwWLMK--DGKMSKSKGNVVDPEE 312
|
..
gi 1958756457 535 VI 536
Cdd:PRK12267 313 LV 314
|
|
| Val_tRNA-synt_C |
pfam10458 |
Valyl tRNA synthetase tRNA binding arm; This domain is found at the C-terminus of Valyl tRNA ... |
855-917 |
3.81e-05 |
|
Valyl tRNA synthetase tRNA binding arm; This domain is found at the C-terminus of Valyl tRNA synthetases.
Pssm-ID: 431296 [Multi-domain] Cd Length: 66 Bit Score: 42.25 E-value: 3.81e-05
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1958756457 855 DPARELGKLQAKRSEAQRQAQRLQERRAASGYSAKVPLEVQEADEVKLQQTEAELRKVDEAIA 917
Cdd:pfam10458 1 DVEKERARLEKELAKLQKEIERVQGKLANPGFVAKAPAEVVEEEKAKLAELEEQAEKLRERLS 63
|
|
| LeuRS_core |
cd00812 |
catalytic core domain of leucyl-tRNA synthetases; Leucyl tRNA synthetase (LeuRS) catalytic ... |
77-136 |
1.97e-04 |
|
catalytic core domain of leucyl-tRNA synthetases; Leucyl tRNA synthetase (LeuRS) catalytic core domain. This class I enzyme is a monomer which aminoacylates the 2'-OH of the nucleotide at the 3' of the appropriate tRNA. The core domain is based on the Rossman fold and is responsible for the ATP-dependent formation of the enzyme bound aminoacyl-adenylate. It contains the characteristic class I HIGH and KMSKS motifs, which are involved in ATP binding. In Aquifex aeolicus, the gene encoding LeuRS is split in two, just before the KMSKS motif. Consequently, LeuRS is a heterodimer, which likely superimposes with the LeuRS monomer found in most other organisms. LeuRS has an insertion in the core domain, which is subject to both deletions and rearrangements and thus differs between prokaryotic LeuRS and archaeal/eukaryotic LeuRS. This editing region hydrolyzes mischarged cognate tRNAs and thus prevents the incorporation of chemically similar amino acids.
Pssm-ID: 173906 [Multi-domain] Cd Length: 314 Bit Score: 44.55 E-value: 1.97e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 77 KWKAEKGDRIYHQLKKLGSSLDWDRACFTMDPKLSATVTEAFVRLHEEGVIYRSTRLVNW 136
Cdd:cd00812 66 DWTEYNIKKMKEQLKRMGFSYDWRREFTTCDPEYYKFTQWLFLKLYEKGLAYKKEAPVNW 125
|
|
| LeuRS_core |
cd00812 |
catalytic core domain of leucyl-tRNA synthetases; Leucyl tRNA synthetase (LeuRS) catalytic ... |
333-536 |
3.26e-04 |
|
catalytic core domain of leucyl-tRNA synthetases; Leucyl tRNA synthetase (LeuRS) catalytic core domain. This class I enzyme is a monomer which aminoacylates the 2'-OH of the nucleotide at the 3' of the appropriate tRNA. The core domain is based on the Rossman fold and is responsible for the ATP-dependent formation of the enzyme bound aminoacyl-adenylate. It contains the characteristic class I HIGH and KMSKS motifs, which are involved in ATP binding. In Aquifex aeolicus, the gene encoding LeuRS is split in two, just before the KMSKS motif. Consequently, LeuRS is a heterodimer, which likely superimposes with the LeuRS monomer found in most other organisms. LeuRS has an insertion in the core domain, which is subject to both deletions and rearrangements and thus differs between prokaryotic LeuRS and archaeal/eukaryotic LeuRS. This editing region hydrolyzes mischarged cognate tRNAs and thus prevents the incorporation of chemically similar amino acids.
Pssm-ID: 173906 [Multi-domain] Cd Length: 314 Bit Score: 43.78 E-value: 3.26e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 333 LRPQWYVRCGEMAQAASAAVTRGDLRILPEAHQRTWHSWMDnirdwcISRQLWWGHRIPayfitvhdpavppgedpdgry 412
Cdd:cd00812 128 LLDQWFLKYSETEWKEKLLKDLEKLDGWPEEVRAMQENWIG------CSRQRYWGTPIP--------------------- 180
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 413 WvsgrteaearekaarefgvspdkislqqdEDVLDTWFSSGLFP--FSIFGWPNQ---------SEDLSVFYPGTLLETG 481
Cdd:cd00812 181 W-----------------------------TDTMESLSDSTWYYarYTDAHNLEQpyegdlefdREEFEYWYPVDIYIGG 231
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1958756457 482 HD-----ILF--FWVArmVMLGLKLTEKLPFREVYLHAIVRdAHGRKMSKSLGNVIDPLDVI 536
Cdd:cd00812 232 KEhapnhLLYsrFNHK--ALFDEGLVTDEPPKGLIVQGMVL-LEGEKMSKSKGNVVTPDEAI 290
|
|
| PLN02224 |
PLN02224 |
methionine-tRNA ligase |
413-537 |
8.96e-04 |
|
methionine-tRNA ligase
Pssm-ID: 177869 [Multi-domain] Cd Length: 616 Bit Score: 43.16 E-value: 8.96e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 413 WVSGRTEAEAREKAAREFGVS-PDkislqQDEDVLDTWFSSGLFPFSIFGWPNQSEDL----SVFYPGTLLETGHDILFF 487
Cdd:PLN02224 260 WIKSGLRDFSISRALVDWGIPvPD-----DDKQTIYVWFDALLGYISALTEDNKQQNLetavSFGWPASLHLIGKDILRF 334
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....
gi 1958756457 488 ----WVARMVMLGLKLTeKLPFREVYLhaiVRDahGRKMSKSLGNVIDPLDVIH 537
Cdd:PLN02224 335 havyWPAMLMSAGLELP-KMVFGHGFL---TKD--GMKMGKSLGNTLEPFELVQ 382
|
|
| MetRS_core |
cd00814 |
catalytic core domain of methioninyl-tRNA synthetases; Methionine tRNA synthetase (MetRS) ... |
370-536 |
1.73e-03 |
|
catalytic core domain of methioninyl-tRNA synthetases; Methionine tRNA synthetase (MetRS) catalytic core domain. This class I enzyme aminoacylates the 2'-OH of the nucleotide at the 3' of the appropriate tRNA. MetRS, which consists of the core domain and an anti-codon binding domain, functions as a monomer. However, in some species the anti-codon binding domain is followed by an EMAP domain. In this case, MetRS functions as a homodimer. The core domain is based on the Rossman fold and is responsible for the ATP-dependent formation of the enzyme bound aminoacyl-adenylate. It contains the characteristic class I HIGH and KMSKS motifs, which are involved in ATP binding. As a result of a deletion event, MetRS has a significantly shorter core domain insertion than IleRS, ValRS, and LeuR. Consequently, the MetRS insertion lacks the editing function.
Pssm-ID: 173907 [Multi-domain] Cd Length: 319 Bit Score: 41.36 E-value: 1.73e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 370 SWMDN-IRDWCISRQLW-WGhrIPayfitvhdpaVPpgEDPDGRYWVsgrteaearekaarefgvspdkislqqdedvld 447
Cdd:cd00814 173 SWLKEgLKDLSITRDLFdWG--IP----------VP--LDPGKVIYV--------------------------------- 205
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958756457 448 tWF-------SSGLFPFSIFG-----WPNQSEDLSVFypgtlletGHDILFF----WVArMVM-LGLKLTEKLPfrevyl 510
Cdd:cd00814 206 -WFdaligyiSATGYYNEEWGnswwwKDGWPELVHFI--------GKDIIRFhaiyWPA-MLLgAGLPLPTRIV------ 269
|
170 180 190
....*....|....*....|....*....|..
gi 1958756457 511 haivrdAH------GRKMSKSLGNVIDPLDVI 536
Cdd:cd00814 270 ------AHgyltveGKKMSKSRGNVVDPDDLL 295
|
|
| |
