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Conserved domains on  [gi|1958778498|ref|XP_038966701|]
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regulator of chromosome condensation isoform X1 [Rattus norvegicus]

Protein Classification

RCC1 domain-containing protein( domain architecture ID 11474102)

RCC1 (regulator of chromosome condensation) domain-containing protein similar to Arabidopsis UVR8 (UV RESISTANCE LOCUS 8), which plays an important role in mediating the effects of UV-B radiation on pathogen resistance by controlling the expression of the sinapate biosynthetic pathway.

Gene Ontology:  GO:0003682|GO:0005085
PubMed:  9510255|18442486

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ATS1 COG5184
Alpha-tubulin suppressor ATS1 and related RCC1 domain-containing proteins [Cell cycle control, ...
 45-402 1.28e-54

Alpha-tubulin suppressor ATS1 and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton];


:

Pssm-ID: 444065 [Multi-domain]  Cd Length: 343  Bit Score: 184.80  E-value: 1.28e-54
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958778498  45 TEPGLVLTLGQGDVGQLGLGESVlERKKPALVPLLQDVVQAEAGGMHTVCLSQSGQVYSFGCNDEGALGRDTSVEGSemV 124
Cdd:COG5184    14 KSDGTVWCWGDNSYGQLGDGTTT-DRSTPVRVPGLSNVVAVAAGGDHTCALKADGTVWCWGNNSYGQLGDGTTTDRT--T 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958778498 125 PGKVELQEKVVQVSAGDSHTAALTEDGRVFLWGSfrDNNGVIGLLEPMKKSmVPVQVQL-DTQVVKVASGNDHLVMLTTD 203
Cdd:COG5184    91 PVKVPGLTGVVAVAAGYYHSCALKSDGTVWCWGD--NSSGQLGDGTTTNRL-TPVQVDAgLSGVVAIAAGGYHTCALKSD 167

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958778498 204 GDLYTLGCGEQGQLGrvpelFANRGGRqglerlLVPRCVllksRGTRGrvrFQDAFCGAYFTFAISREGHVYGFGLSNYH 283
Cdd:COG5184   168 GTVWCWGANSYGQLG-----DGTTTDR------PTPVQV----GGLSG---VVAVAAGGDHSCALKSDGTVWCWGSNSSG 229

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958778498 284 QLGTPGTGSCFIPQNLTSFKNstksWVGFSGGQHHTVCMDSEGKAYSLGRAEYGRLGLGeGAEEKSIPTLISRLPVVSSV 363
Cdd:COG5184   230 QLGDGTTTDRATPVQVAGLTG----VVAIAAGGSHTCALKSDGTVWCWGDNSYGQLGDG-TTTDRSTPVKVPGLSGVVAV 304

                         330       340       350
                  ....*....|....*....|....*....|....*....
gi 1958778498 364 ACGASVGYAVSKDGRVFAWGMGTNYQLGTGQEDDAWSPV 402
Cdd:COG5184   305 AAGSSHTCALLTDGTVWCWGDNAYGQLGDGTTTDRSTPV 343
 
Name Accession Description Interval E-value
ATS1 COG5184
Alpha-tubulin suppressor ATS1 and related RCC1 domain-containing proteins [Cell cycle control, ...
 45-402 1.28e-54

Alpha-tubulin suppressor ATS1 and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton];


Pssm-ID: 444065 [Multi-domain]  Cd Length: 343  Bit Score: 184.80  E-value: 1.28e-54
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958778498  45 TEPGLVLTLGQGDVGQLGLGESVlERKKPALVPLLQDVVQAEAGGMHTVCLSQSGQVYSFGCNDEGALGRDTSVEGSemV 124
Cdd:COG5184    14 KSDGTVWCWGDNSYGQLGDGTTT-DRSTPVRVPGLSNVVAVAAGGDHTCALKADGTVWCWGNNSYGQLGDGTTTDRT--T 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958778498 125 PGKVELQEKVVQVSAGDSHTAALTEDGRVFLWGSfrDNNGVIGLLEPMKKSmVPVQVQL-DTQVVKVASGNDHLVMLTTD 203
Cdd:COG5184    91 PVKVPGLTGVVAVAAGYYHSCALKSDGTVWCWGD--NSSGQLGDGTTTNRL-TPVQVDAgLSGVVAIAAGGYHTCALKSD 167

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958778498 204 GDLYTLGCGEQGQLGrvpelFANRGGRqglerlLVPRCVllksRGTRGrvrFQDAFCGAYFTFAISREGHVYGFGLSNYH 283
Cdd:COG5184   168 GTVWCWGANSYGQLG-----DGTTTDR------PTPVQV----GGLSG---VVAVAAGGDHSCALKSDGTVWCWGSNSSG 229

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958778498 284 QLGTPGTGSCFIPQNLTSFKNstksWVGFSGGQHHTVCMDSEGKAYSLGRAEYGRLGLGeGAEEKSIPTLISRLPVVSSV 363
Cdd:COG5184   230 QLGDGTTTDRATPVQVAGLTG----VVAIAAGGSHTCALKSDGTVWCWGDNSYGQLGDG-TTTDRSTPVKVPGLSGVVAV 304

                         330       340       350
                  ....*....|....*....|....*....|....*....
gi 1958778498 364 ACGASVGYAVSKDGRVFAWGMGTNYQLGTGQEDDAWSPV 402
Cdd:COG5184   305 AAGSSHTCALLTDGTVWCWGDNAYGQLGDGTTTDRSTPV 343
RCC1 pfam00415
Regulator of chromosome condensation (RCC1) repeat;
376-427 3.22e-12

Regulator of chromosome condensation (RCC1) repeat;


Pssm-ID: 395335 [Multi-domain]  Cd Length: 50  Bit Score: 60.99  E-value: 3.22e-12
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1958778498 376 DGRVFAWGMGTNYQLGTGQEDDAWSPVEMTGkqLENREVLTVSSGGQHTVLL 427
Cdd:pfam00415   1 DGRVYTWGRNDYGQLGLGTTENVLVPQKVEG--LSGNKVVQVACGGDHTVAL 50
 
Name Accession Description Interval E-value
ATS1 COG5184
Alpha-tubulin suppressor ATS1 and related RCC1 domain-containing proteins [Cell cycle control, ...
 45-402 1.28e-54

Alpha-tubulin suppressor ATS1 and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton];


Pssm-ID: 444065 [Multi-domain]  Cd Length: 343  Bit Score: 184.80  E-value: 1.28e-54
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958778498  45 TEPGLVLTLGQGDVGQLGLGESVlERKKPALVPLLQDVVQAEAGGMHTVCLSQSGQVYSFGCNDEGALGRDTSVEGSemV 124
Cdd:COG5184    14 KSDGTVWCWGDNSYGQLGDGTTT-DRSTPVRVPGLSNVVAVAAGGDHTCALKADGTVWCWGNNSYGQLGDGTTTDRT--T 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958778498 125 PGKVELQEKVVQVSAGDSHTAALTEDGRVFLWGSfrDNNGVIGLLEPMKKSmVPVQVQL-DTQVVKVASGNDHLVMLTTD 203
Cdd:COG5184    91 PVKVPGLTGVVAVAAGYYHSCALKSDGTVWCWGD--NSSGQLGDGTTTNRL-TPVQVDAgLSGVVAIAAGGYHTCALKSD 167

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958778498 204 GDLYTLGCGEQGQLGrvpelFANRGGRqglerlLVPRCVllksRGTRGrvrFQDAFCGAYFTFAISREGHVYGFGLSNYH 283
Cdd:COG5184   168 GTVWCWGANSYGQLG-----DGTTTDR------PTPVQV----GGLSG---VVAVAAGGDHSCALKSDGTVWCWGSNSSG 229

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958778498 284 QLGTPGTGSCFIPQNLTSFKNstksWVGFSGGQHHTVCMDSEGKAYSLGRAEYGRLGLGeGAEEKSIPTLISRLPVVSSV 363
Cdd:COG5184   230 QLGDGTTTDRATPVQVAGLTG----VVAIAAGGSHTCALKSDGTVWCWGDNSYGQLGDG-TTTDRSTPVKVPGLSGVVAV 304

                         330       340       350
                  ....*....|....*....|....*....|....*....
gi 1958778498 364 ACGASVGYAVSKDGRVFAWGMGTNYQLGTGQEDDAWSPV 402
Cdd:COG5184   305 AAGSSHTCALLTDGTVWCWGDNAYGQLGDGTTTDRSTPV 343
ATS1 COG5184
Alpha-tubulin suppressor ATS1 and related RCC1 domain-containing proteins [Cell cycle control, ...
 83-432 3.07e-53

Alpha-tubulin suppressor ATS1 and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton];


Pssm-ID: 444065 [Multi-domain]  Cd Length: 343  Bit Score: 181.33  E-value: 3.07e-53
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958778498  83 VQAEAGGMHTVCLSQSGQVYSFGCNDEGALGRDTSVEGSemVPGKVELQEKVVQVSAGDSHTAALTEDGRVFLWGSfrDN 162
Cdd:COG5184     1 TQVAAGGSHSCALKSDGTVWCWGDNSYGQLGDGTTTDRS--TPVRVPGLSNVVAVAAGGDHTCALKADGTVWCWGN--NS 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958778498 163 NGVIGLLEPmKKSMVPVQVQLDTQVVKVASGNDHLVMLTTDGDLYTLGCGEQGQLGRvpelfANRGGRqglerlLVPRCV 242
Cdd:COG5184    77 YGQLGDGTT-TDRTTPVKVPGLTGVVAVAAGYYHSCALKSDGTVWCWGDNSSGQLGD-----GTTTNR------LTPVQV 144

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958778498 243 LLksrgtrGRVRFQDAFCGAYFTFAISREGHVYGFGLSNYHQLGTPGTGSCFIPQNLTSFKNstksWVGFSGGQHHTVCM 322
Cdd:COG5184   145 DA------GLSGVVAIAAGGYHTCALKSDGTVWCWGANSYGQLGDGTTTDRPTPVQVGGLSG----VVAVAAGGDHSCAL 214

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958778498 323 DSEGKAYSLGRAEYGRLGLGeGAEEKSIPTLISRLPVVSSVACGASVGYAVSKDGRVFAWGMGTNYQLGTGQEDDAWSPV 402
Cdd:COG5184   215 KSDGTVWCWGSNSSGQLGDG-TTTDRATPVQVAGLTGVVAIAAGGSHTCALKSDGTVWCWGDNSYGQLGDGTTTDRSTPV 293

                         330       340       350
                  ....*....|....*....|....*....|
gi 1958778498 403 EMTGkqLENreVLTVSSGGQHTVLLVKDKT 432
Cdd:COG5184   294 KVPG--LSG--VVAVAAGSSHTCALLTDGT 319
RCC1 pfam00415
Regulator of chromosome condensation (RCC1) repeat;
376-427 3.22e-12

Regulator of chromosome condensation (RCC1) repeat;


Pssm-ID: 395335 [Multi-domain]  Cd Length: 50  Bit Score: 60.99  E-value: 3.22e-12
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1958778498 376 DGRVFAWGMGTNYQLGTGQEDDAWSPVEMTGkqLENREVLTVSSGGQHTVLL 427
Cdd:pfam00415   1 DGRVYTWGRNDYGQLGLGTTENVLVPQKVEG--LSGNKVVQVACGGDHTVAL 50
RCC1 pfam00415
Regulator of chromosome condensation (RCC1) repeat;
98-147 9.12e-11

Regulator of chromosome condensation (RCC1) repeat;


Pssm-ID: 395335 [Multi-domain]  Cd Length: 50  Bit Score: 56.76  E-value: 9.12e-11
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1958778498  98 SGQVYSFGCNDEGALGRDTSVegSEMVPGKVEL--QEKVVQVSAGDSHTAAL 147
Cdd:pfam00415   1 DGRVYTWGRNDYGQLGLGTTE--NVLVPQKVEGlsGNKVVQVACGGDHTVAL 50
RCC1 pfam00415
Regulator of chromosome condensation (RCC1) repeat;
271-322 9.62e-09

Regulator of chromosome condensation (RCC1) repeat;


Pssm-ID: 395335 [Multi-domain]  Cd Length: 50  Bit Score: 50.98  E-value: 9.62e-09
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1958778498 271 EGHVYGFGLSNYHQLGTPGTGSCFIPQNLTSFKNstKSWVGFSGGQHHTVCM 322
Cdd:pfam00415   1 DGRVYTWGRNDYGQLGLGTTENVLVPQKVEGLSG--NKVVQVACGGDHTVAL 50
RCC1 pfam00415
Regulator of chromosome condensation (RCC1) repeat;
48-95 6.08e-07

Regulator of chromosome condensation (RCC1) repeat;


Pssm-ID: 395335 [Multi-domain]  Cd Length: 50  Bit Score: 45.97  E-value: 6.08e-07
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|
gi 1958778498  48 GLVLTLGQGDVGQLGLGESVlERKKPALVPLLQD--VVQAEAGGMHTVCL 95
Cdd:pfam00415   2 GRVYTWGRNDYGQLGLGTTE-NVLVPQKVEGLSGnkVVQVACGGDHTVAL 50
RCC1_2 pfam13540
Regulator of chromosome condensation (RCC1) repeat;
134-158 8.24e-07

Regulator of chromosome condensation (RCC1) repeat;


Pssm-ID: 463914 [Multi-domain]  Cd Length: 30  Bit Score: 45.11  E-value: 8.24e-07
                          10        20
                  ....*....|....*....|....*
gi 1958778498 134 VVQVSAGDSHTAALTEDGRVFLWGS 158
Cdd:pfam13540   1 VVSVAAGDNHTLALTSDGRVYCWGD 25
RCC1 pfam00415
Regulator of chromosome condensation (RCC1) repeat;
203-268 3.62e-06

Regulator of chromosome condensation (RCC1) repeat;


Pssm-ID: 395335 [Multi-domain]  Cd Length: 50  Bit Score: 43.66  E-value: 3.62e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1958778498 203 DGDLYTLGCGEQGQLGRVPElfanrggrqglERLLVPRCVllksrGTRGRVRFQDAFCGAYFTFAI 268
Cdd:pfam00415   1 DGRVYTWGRNDYGQLGLGTT-----------ENVLVPQKV-----EGLSGNKVVQVACGGDHTVAL 50
RCC1 pfam00415
Regulator of chromosome condensation (RCC1) repeat;
325-368 7.18e-05

Regulator of chromosome condensation (RCC1) repeat;


Pssm-ID: 395335 [Multi-domain]  Cd Length: 50  Bit Score: 40.19  E-value: 7.18e-05
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*.
gi 1958778498 325 EGKAYSLGRAEYGRLGLGEGaEEKSIPTLISRLPV--VSSVACGAS 368
Cdd:pfam00415   1 DGRVYTWGRNDYGQLGLGTT-ENVLVPQKVEGLSGnkVVQVACGGD 45
RCC1 pfam00415
Regulator of chromosome condensation (RCC1) repeat;
150-200 2.93e-04

Regulator of chromosome condensation (RCC1) repeat;


Pssm-ID: 395335 [Multi-domain]  Cd Length: 50  Bit Score: 38.27  E-value: 2.93e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1958778498 150 DGRVFLWGsfRDNNGVIGlLEPMKKSMVPVQVQLDTQ--VVKVASGNDHLVML 200
Cdd:pfam00415   1 DGRVYTWG--RNDYGQLG-LGTTENVLVPQKVEGLSGnkVVQVACGGDHTVAL 50
RCC1_2 pfam13540
Regulator of chromosome condensation (RCC1) repeat;
82-110 7.52e-04

Regulator of chromosome condensation (RCC1) repeat;


Pssm-ID: 463914 [Multi-domain]  Cd Length: 30  Bit Score: 36.63  E-value: 7.52e-04
                          10        20
                  ....*....|....*....|....*....
gi 1958778498  82 VVQAEAGGMHTVCLSQSGQVYSFGCNDEG 110
Cdd:pfam13540   1 VVSVAAGDNHTLALTSDGRVYCWGDNSYG 29
RCC1_2 pfam13540
Regulator of chromosome condensation (RCC1) repeat;
360-389 1.18e-03

Regulator of chromosome condensation (RCC1) repeat;


Pssm-ID: 463914 [Multi-domain]  Cd Length: 30  Bit Score: 36.25  E-value: 1.18e-03
                          10        20        30
                  ....*....|....*....|....*....|
gi 1958778498 360 VSSVACGASVGYAVSKDGRVFAWGMGTNYQ 389
Cdd:pfam13540   1 VVSVAAGDNHTLALTSDGRVYCWGDNSYGQ 30
RCC1_2 pfam13540
Regulator of chromosome condensation (RCC1) repeat;
260-284 2.42e-03

Regulator of chromosome condensation (RCC1) repeat;


Pssm-ID: 463914 [Multi-domain]  Cd Length: 30  Bit Score: 35.09  E-value: 2.42e-03
                          10        20
                  ....*....|....*....|....*
gi 1958778498 260 CGAYFTFAISREGHVYGFGLSNYHQ 284
Cdd:pfam13540   6 AGDNHTLALTSDGRVYCWGDNSYGQ 30
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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