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Conserved domains on  [gi|2462595049|ref|XP_054204964|]
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magnesium transporter NIPA3 isoform X2 [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
EamA super family cl23754
EamA-like transporter family; This family includes many hypothetical membrane proteins of ...
 66-116 3.23e-09

EamA-like transporter family; This family includes many hypothetical membrane proteins of unknown function. Many of the proteins contain two copies of the aligned region. The family used to be known as DUF6. Members of this family usually carry 5+5 transmembrane domains, and this domain attempts to model five of these.


The actual alignment was detected with superfamily member pfam05653:

Pssm-ID: 474045  Cd Length: 295  Bit Score: 54.77  E-value: 3.23e-09
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 2462595049  66 YSLYVGLVLAVSSSIFIGSSFILKKKGLLQLASKGFTRAGQGGHSYLKEWL 116
Cdd:pfam05653   1 TDFYIGVGLAISSSIFIGSSFIIKKKGLLRLARKGHPRAGAGGYGYLKEWL 51
 
Name Accession Description Interval E-value
Mg_trans_NIPA pfam05653
Magnesium transporter NIPA; NIPA (nonimprinted in Prader-Willi/Angelman syndrome) is a family ...
 66-116 3.23e-09

Magnesium transporter NIPA; NIPA (nonimprinted in Prader-Willi/Angelman syndrome) is a family of integral membrane proteins which function as magnesium transporters.


Pssm-ID: 398984  Cd Length: 295  Bit Score: 54.77  E-value: 3.23e-09
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 2462595049  66 YSLYVGLVLAVSSSIFIGSSFILKKKGLLQLASKGFTRAGQGGHSYLKEWL 116
Cdd:pfam05653   1 TDFYIGVGLAISSSIFIGSSFIIKKKGLLRLARKGHPRAGAGGYGYLKEWL 51
 
Name Accession Description Interval E-value
Mg_trans_NIPA pfam05653
Magnesium transporter NIPA; NIPA (nonimprinted in Prader-Willi/Angelman syndrome) is a family ...
 66-116 3.23e-09

Magnesium transporter NIPA; NIPA (nonimprinted in Prader-Willi/Angelman syndrome) is a family of integral membrane proteins which function as magnesium transporters.


Pssm-ID: 398984  Cd Length: 295  Bit Score: 54.77  E-value: 3.23e-09
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 2462595049  66 YSLYVGLVLAVSSSIFIGSSFILKKKGLLQLASKGFTRAGQGGHSYLKEWL 116
Cdd:pfam05653   1 TDFYIGVGLAISSSIFIGSSFIIKKKGLLRLARKGHPRAGAGGYGYLKEWL 51
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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