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Conserved domains on  [gi|58865732|ref|NP_001012081|]
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DNA-directed RNA polymerase III subunit RPC3 [Rattus norvegicus]

Protein Classification

HTH_9 and RNA_pol_Rpc82 domain-containing protein( domain architecture ID 10548595)

HTH_9 and RNA_pol_Rpc82 domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
RNA_pol_Rpc82 pfam05645
RNA polymerase III subunit RPC82; This family consists of several DNA-directed RNA polymerase ...
 146-344 2.20e-45

RNA polymerase III subunit RPC82; This family consists of several DNA-directed RNA polymerase III polypeptides which are related to the Saccharomyces cerevisiae RPC82 protein. RNA polymerase C (III) promotes the transcription of tRNA and 5S RNA genes. In Saccharomyces cerevisiae, the enzyme is composed of 15 subunits, ranging from 160 to about 10 kDa.


:

Pssm-ID: 398977  Cd Length: 233  Bit Score: 159.17  E-value: 2.20e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58865732   146 NAFVRLADTHFVQRCP---LVPDTDSSDPGPPPPAPNL-----------VINEK--------DMYLVPKLSLIGkgkrRR 203
Cdd:pfam05645   1 ETFVKLVEAGFLIRVPkfhFRPIPDLWNQLYEEHLKSTprssttseikrRAEAKvkaktelrDLRESPEILLRG----RR 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58865732   204 SSDEDAAGEPKAKKprctdneepTPDDGIYWQVNLDRFHQHFRDQAIVSAVANRMDQTSSEIVRTMLRMSEITTPSGAPF 283
Cdd:pfam05645  77 GSLADTTDNGTGKK---------RLDPGLVWRVNLERFHKHLRDEALVDLVKSRIGSTTAEVYRAALRLSESRTPPCSAP 147

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58865732   284 -----TQPLSSNEIFRSLPVGYNISK--------------------QVLDQYLTLLADDPLEFIGKAGDSGGGMYVINLH 338
Cdd:pfam05645 148 lvddpSITFTANDIARALPKSLDLSMsigkrssnssqsapkkeeslSLLDQHLKLLASDPLPFLREIGPSGGGQYTVDFS 227


                  ....*.
gi 58865732   339 KALASL 344
Cdd:pfam05645 228 RLIEQL 233
HTH_9 pfam08221
RNA polymerase III subunit RPC82 helix-turn-helix domain; This family consists of several ...
 7-68 7.55e-22

RNA polymerase III subunit RPC82 helix-turn-helix domain; This family consists of several DNA-directed RNA polymerase III polypeptides which are related to the Saccharomyces cerevisiae RPC82 protein. RNA polymerase C (III) promotes the transcription of tRNA and 5S RNA genes. In Saccharomyces cerevisiae, the enzyme is composed of 15 subunits, ranging from 160 to about 10 kDa. This region is a probably DNA-binding helix-turn-helix.


:

Pssm-ID: 400500  Cd Length: 62  Bit Score: 88.83  E-value: 7.55e-22
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 58865732     7 KLCSLLLQEHFGEIVEKIGVHLIRTGSQPLRVIAHDTKASLDQVKKALCVLIHHNLVIYHVH 68
Cdd:pfam08221   1 FLCTELLEEHFGEVVAKVVSTLLRKGRLTLREIVKLTKLSLDQVKKSLVSLIQHNCVQYFEE 62
 
Name Accession Description Interval E-value
RNA_pol_Rpc82 pfam05645
RNA polymerase III subunit RPC82; This family consists of several DNA-directed RNA polymerase ...
 146-344 2.20e-45

RNA polymerase III subunit RPC82; This family consists of several DNA-directed RNA polymerase III polypeptides which are related to the Saccharomyces cerevisiae RPC82 protein. RNA polymerase C (III) promotes the transcription of tRNA and 5S RNA genes. In Saccharomyces cerevisiae, the enzyme is composed of 15 subunits, ranging from 160 to about 10 kDa.


Pssm-ID: 398977  Cd Length: 233  Bit Score: 159.17  E-value: 2.20e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58865732   146 NAFVRLADTHFVQRCP---LVPDTDSSDPGPPPPAPNL-----------VINEK--------DMYLVPKLSLIGkgkrRR 203
Cdd:pfam05645   1 ETFVKLVEAGFLIRVPkfhFRPIPDLWNQLYEEHLKSTprssttseikrRAEAKvkaktelrDLRESPEILLRG----RR 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58865732   204 SSDEDAAGEPKAKKprctdneepTPDDGIYWQVNLDRFHQHFRDQAIVSAVANRMDQTSSEIVRTMLRMSEITTPSGAPF 283
Cdd:pfam05645  77 GSLADTTDNGTGKK---------RLDPGLVWRVNLERFHKHLRDEALVDLVKSRIGSTTAEVYRAALRLSESRTPPCSAP 147

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58865732   284 -----TQPLSSNEIFRSLPVGYNISK--------------------QVLDQYLTLLADDPLEFIGKAGDSGGGMYVINLH 338
Cdd:pfam05645 148 lvddpSITFTANDIARALPKSLDLSMsigkrssnssqsapkkeeslSLLDQHLKLLASDPLPFLREIGPSGGGQYTVDFS 227


                  ....*.
gi 58865732   339 KALASL 344
Cdd:pfam05645 228 RLIEQL 233
HTH_9 pfam08221
RNA polymerase III subunit RPC82 helix-turn-helix domain; This family consists of several ...
 7-68 7.55e-22

RNA polymerase III subunit RPC82 helix-turn-helix domain; This family consists of several DNA-directed RNA polymerase III polypeptides which are related to the Saccharomyces cerevisiae RPC82 protein. RNA polymerase C (III) promotes the transcription of tRNA and 5S RNA genes. In Saccharomyces cerevisiae, the enzyme is composed of 15 subunits, ranging from 160 to about 10 kDa. This region is a probably DNA-binding helix-turn-helix.


Pssm-ID: 400500  Cd Length: 62  Bit Score: 88.83  E-value: 7.55e-22
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 58865732     7 KLCSLLLQEHFGEIVEKIGVHLIRTGSQPLRVIAHDTKASLDQVKKALCVLIHHNLVIYHVH 68
Cdd:pfam08221   1 FLCTELLEEHFGEVVAKVVSTLLRKGRLTLREIVKLTKLSLDQVKKSLVSLIQHNCVQYFEE 62
 
Name Accession Description Interval E-value
RNA_pol_Rpc82 pfam05645
RNA polymerase III subunit RPC82; This family consists of several DNA-directed RNA polymerase ...
 146-344 2.20e-45

RNA polymerase III subunit RPC82; This family consists of several DNA-directed RNA polymerase III polypeptides which are related to the Saccharomyces cerevisiae RPC82 protein. RNA polymerase C (III) promotes the transcription of tRNA and 5S RNA genes. In Saccharomyces cerevisiae, the enzyme is composed of 15 subunits, ranging from 160 to about 10 kDa.


Pssm-ID: 398977  Cd Length: 233  Bit Score: 159.17  E-value: 2.20e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58865732   146 NAFVRLADTHFVQRCP---LVPDTDSSDPGPPPPAPNL-----------VINEK--------DMYLVPKLSLIGkgkrRR 203
Cdd:pfam05645   1 ETFVKLVEAGFLIRVPkfhFRPIPDLWNQLYEEHLKSTprssttseikrRAEAKvkaktelrDLRESPEILLRG----RR 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58865732   204 SSDEDAAGEPKAKKprctdneepTPDDGIYWQVNLDRFHQHFRDQAIVSAVANRMDQTSSEIVRTMLRMSEITTPSGAPF 283
Cdd:pfam05645  77 GSLADTTDNGTGKK---------RLDPGLVWRVNLERFHKHLRDEALVDLVKSRIGSTTAEVYRAALRLSESRTPPCSAP 147

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58865732   284 -----TQPLSSNEIFRSLPVGYNISK--------------------QVLDQYLTLLADDPLEFIGKAGDSGGGMYVINLH 338
Cdd:pfam05645 148 lvddpSITFTANDIARALPKSLDLSMsigkrssnssqsapkkeeslSLLDQHLKLLASDPLPFLREIGPSGGGQYTVDFS 227


                  ....*.
gi 58865732   339 KALASL 344
Cdd:pfam05645 228 RLIEQL 233
HTH_9 pfam08221
RNA polymerase III subunit RPC82 helix-turn-helix domain; This family consists of several ...
 7-68 7.55e-22

RNA polymerase III subunit RPC82 helix-turn-helix domain; This family consists of several DNA-directed RNA polymerase III polypeptides which are related to the Saccharomyces cerevisiae RPC82 protein. RNA polymerase C (III) promotes the transcription of tRNA and 5S RNA genes. In Saccharomyces cerevisiae, the enzyme is composed of 15 subunits, ranging from 160 to about 10 kDa. This region is a probably DNA-binding helix-turn-helix.


Pssm-ID: 400500  Cd Length: 62  Bit Score: 88.83  E-value: 7.55e-22
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 58865732     7 KLCSLLLQEHFGEIVEKIGVHLIRTGSQPLRVIAHDTKASLDQVKKALCVLIHHNLVIYHVH 68
Cdd:pfam08221   1 FLCTELLEEHFGEVVAKVVSTLLRKGRLTLREIVKLTKLSLDQVKKSLVSLIQHNCVQYFEE 62
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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