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Conserved domains on  [gi|2174213131|ref|NP_001012492|]
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probable E3 ubiquitin-protein ligase HERC6 [Rattus norvegicus]

Protein Classification

E3 ubiquitin-protein ligase HERC family protein( domain architecture ID 18804227)

E3 ubiquitin-protein ligase HERC (HECT and RCC1 domain) family protein similar to human E3 ISG15--protein ligase HERC5, the major E3 ligase for ISG15 conjugation, that functions as part of the ISGylation machinery that recognizes target proteins in a broad and relatively non-specific manner

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
HECTc cd00078
HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It ...
 682-1023 1.31e-119

HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ubiquitin molecules to the end of growing ubiquitin chains.


:

Pssm-ID: 238033 [Multi-domain]  Cd Length: 352  Bit Score: 370.36  E-value: 1.31e-119
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2174213131  682 FILKVRRSHLVEDTLRQLRQAEDFDLRKTLSVGFINEIRPEGGGVSSEFFHCIFEEMTDPKYEMFMYPENGSN-MWFPVN 760
Cdd:cd00078      1 LKITVRRDRILEDALRQLSKVSSSDLKKVLEVEFVGEEGIDAGGVTREFFTLVSKELFNPSYGLFRYTPDDSGlLYPNPS 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2174213131  761 PKF---EKSRYFLFGILCGLSLNNLNVINLSFPLALYKKLLEQKPSLEDLKDLSLLLGRNLQEVLNCEaGVIEELHMYFS 837
Cdd:cd00078     81 SFAdedHLKLFRFLGRLLGKALYEGRLLDLPFSRAFYKKLLGKPLSLEDLEELDPELYKSLKELLDND-GDEDDLELTFT 159

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2174213131  838 I-----YWDQRDVDLIPDGISVPVNETNKRDYVSKCVDYIFNISIKTIYDEFHRGFYKVCNRDSIRHFQPEELMAAIIGN 912
Cdd:cd00078    160 IeldssFGGAVTVELKPGGRDIPVTNENKEEYVDLYVDYRLNKGIEEQVEAFRDGFSEVIPEELLSLFTPEELELLICGS 239

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2174213131  913 PTCDWKQFENNSKYENGYSKSHPTILLFWKAFHELTLDEKKKFLLFLTGCDRLHVKGLQNEGIRFRCPEVFSERDN-PRS 991
Cdd:cd00078    240 EDIDLEDLKKNTEYKGGYSSDSPTIQWFWEVLESFTNEERKKFLQFVTGSSRLPVGGFADLNPKFTIRRVGSPDDRlPTA 319

                          330       340       350
                   ....*....|....*....|....*....|..
gi 2174213131  992 LTCHSILDLPKYSTMRRMKEALQVAINNNKGF 1023
Cdd:cd00078    320 HTCFNLLKLPPYSSKEILREKLLYAINEGAGF 351
ATS1 COG5184
Alpha-tubulin suppressor ATS1 and related RCC1 domain-containing proteins [Cell cycle control, ...
 27-313 1.07e-63

Alpha-tubulin suppressor ATS1 and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton];


:

Pssm-ID: 444065 [Multi-domain]  Cd Length: 343  Bit Score: 219.46  E-value: 1.07e-63
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2174213131   27 ASGERHSLLLFSNHRVYSCGDNSRGQLGQKSPQSTKRPEPIQALSTVhIDlVSCGKEHSVAVCHQGRVFTWGAGSEGQLG 106
Cdd:COG5184      4 AAGGSHSCALKSDGTVWCWGDNSYGQLGDGTTTDRSTPVRVPGLSNV-VA-VAAGGDHTCALKADGTVWCWGNNSYGQLG 81

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2174213131  107 IGESkEISFMPTKINSLAGIKiiQVSCGHYHSLALSEDGQVFSWGSNRQGQLGLGNNLcSQASPQKV-KSLEGIplAQVA 185
Cdd:COG5184     82 DGTT-TDRTTPVKVPGLTGVV--AVAAGYYHSCALKSDGTVWCWGDNSSGQLGDGTTT-NRLTPVQVdAGLSGV--VAIA 155

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2174213131  186 AGGTHSFALSLMGTSFGWGNNRSGQLalsGNSAKEQIYKPHSIGALKtlNVVYISCGYEHTSVLTEDGQVFTFGGSSSEQ 265
Cdd:COG5184    156 AGGYHTCALKSDGTVWCWGANSYGQL---GDGTTTDRPTPVQVGGLS--GVVAVAAGGDHSCALKSDGTVWCWGSNSSGQ 230

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*...
gi 2174213131  266 LQHSPRSGRGGPQLIEGIGGhVSQIECGSYHTIAyVYTTGQVVSLGRG 313
Cdd:COG5184    231 LGDGTTTDRATPVQVAGLTG-VVAIAAGGSHTCA-LKSDGTVWCWGDN 276
 
Name Accession Description Interval E-value
HECTc cd00078
HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It ...
 682-1023 1.31e-119

HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ubiquitin molecules to the end of growing ubiquitin chains.


Pssm-ID: 238033 [Multi-domain]  Cd Length: 352  Bit Score: 370.36  E-value: 1.31e-119
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2174213131  682 FILKVRRSHLVEDTLRQLRQAEDFDLRKTLSVGFINEIRPEGGGVSSEFFHCIFEEMTDPKYEMFMYPENGSN-MWFPVN 760
Cdd:cd00078      1 LKITVRRDRILEDALRQLSKVSSSDLKKVLEVEFVGEEGIDAGGVTREFFTLVSKELFNPSYGLFRYTPDDSGlLYPNPS 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2174213131  761 PKF---EKSRYFLFGILCGLSLNNLNVINLSFPLALYKKLLEQKPSLEDLKDLSLLLGRNLQEVLNCEaGVIEELHMYFS 837
Cdd:cd00078     81 SFAdedHLKLFRFLGRLLGKALYEGRLLDLPFSRAFYKKLLGKPLSLEDLEELDPELYKSLKELLDND-GDEDDLELTFT 159

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2174213131  838 I-----YWDQRDVDLIPDGISVPVNETNKRDYVSKCVDYIFNISIKTIYDEFHRGFYKVCNRDSIRHFQPEELMAAIIGN 912
Cdd:cd00078    160 IeldssFGGAVTVELKPGGRDIPVTNENKEEYVDLYVDYRLNKGIEEQVEAFRDGFSEVIPEELLSLFTPEELELLICGS 239

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2174213131  913 PTCDWKQFENNSKYENGYSKSHPTILLFWKAFHELTLDEKKKFLLFLTGCDRLHVKGLQNEGIRFRCPEVFSERDN-PRS 991
Cdd:cd00078    240 EDIDLEDLKKNTEYKGGYSSDSPTIQWFWEVLESFTNEERKKFLQFVTGSSRLPVGGFADLNPKFTIRRVGSPDDRlPTA 319

                          330       340       350
                   ....*....|....*....|....*....|..
gi 2174213131  992 LTCHSILDLPKYSTMRRMKEALQVAINNNKGF 1023
Cdd:cd00078    320 HTCFNLLKLPPYSSKEILREKLLYAINEGAGF 351
HECT pfam00632
HECT-domain (ubiquitin-transferase); The name HECT comes from Homologous to the E6-AP Carboxyl ...
 734-1023 3.51e-77

HECT-domain (ubiquitin-transferase); The name HECT comes from Homologous to the E6-AP Carboxyl Terminus.


Pssm-ID: 459880  Cd Length: 304  Bit Score: 255.23  E-value: 3.51e-77
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2174213131  734 IFEEMTDPKYEMFMYPENGSN-MWF----PVNPKFEKSRYF-LFGILCGLSLNNLNVINLSFPLALYKKLLEQKPSLEDL 807
Cdd:pfam00632    3 LSKELFDPNYGLFEYETEDDRtYWFnpssSESPDLELLDYFkFLGKLLGKAIYNGILLDLPFPPFFYKKLLGEPLTLEDL 82

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2174213131  808 KDLSLLLGRNLQEVLNCEAGVIEELHMYFSI--YWDQRDVDLIPDGISVPVNETNKRDYVSKCVDYIFNISIKTIYDEFH 885
Cdd:pfam00632   83 ESIDPELYKSLKSLLNMDNDDDEDLGLTFTIpvFGESKTIELIPNGRNIPVTNENKEEYIRLYVDYRLNKSIEPQLEAFR 162

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2174213131  886 RGFYKVCNRDSIRHFQPEELMAAIIGNPTCDWKQFENNSKYENGYSKSHPTILLFWKAFHELTLDEKKKFLLFLTGCDRL 965
Cdd:pfam00632  163 KGFYSVIPKEALSLFTPEELELLICGSPEIDVEDLKKNTEYDGGYTKNSPTIQWFWEILEEFSPEQRRLFLKFVTGSSRL 242

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 2174213131  966 HVKGLQN-EGIRFRCPEVFSERDNPRSLTCHSILDLPKYSTMRRMKEALQVAINNNKGF 1023
Cdd:pfam00632  243 PVGGFKSlPKFTIVRKGGDDDDRLPTAHTCFNRLKLPDYSSKEILKEKLLIAIEEGEGF 301
HECTc smart00119
Domain Homologous to E6-AP Carboxyl Terminus with; E3 ubiquitin-protein ligases. Can bind to ...
 706-1023 1.91e-76

Domain Homologous to E6-AP Carboxyl Terminus with; E3 ubiquitin-protein ligases. Can bind to E2 enzymes.


Pssm-ID: 214523  Cd Length: 328  Bit Score: 254.08  E-value: 1.91e-76
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2174213131   706 DLRK-TLSVGFINEIRPEGGGVSSEFFHCIFEEMTDPKYEMFMYPENGSNMWFPVNP---KFEKSRYFLF-GILCGLSLN 780
Cdd:smart00119    1 DLKKrVLEIEFEGEEGLDGGGVTREFFFLLSKELFNPDYGLFRYSPNDYLLYPNPRSgfaNEEHLSYFRFiGRVLGKALY 80

                            90       100       110       120       130       140       150       160
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2174213131   781 NLNVINLSFPLALYKKLLEQKPSLEDLKDLSLLLGRNLQEvLNCEAGVIEELHMYFSI-----YWDQRDVDLIPDGISVP 855
Cdd:smart00119   81 DNRLLDLFFARPFYKKLLGKPVTLHDLESLDPELYKSLKW-LLLNNDTSEELDLTFSIvltseFGQVKVVELKPGGSNIP 159

                           170       180       190       200       210       220       230       240
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2174213131   856 VNETNKRDYVSKCVDYIFNISIKTIYDEFHRGFYKVCNRDSIRHFQPEELMAAIIGNPTCDWKQFENNSKYENGYSKSHP 935
Cdd:smart00119  160 VTEENKKEYVHLVIEYRLNKGIEKQLEAFREGFSEVIPENLLKLFDPEELELLICGSPEIDVDDLKSNTEYKGGYSANSQ 239

                           250       260       270       280       290       300       310       320
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2174213131   936 TILLFWKAFHELTLDEKKKFLLFLTGCDRLHVKGLQNEGIRFRCPEVFSERDN-PRSLTCHSILDLPKYSTMRRMKEALQ 1014
Cdd:smart00119  240 TIKWFWEVVESFTNEERRKLLQFVTGSSRLPVGGFAALSPKFTIRKAGSDDERlPTAHTCFNRLKLPPYSSKEILREKLL 319


                    ....*....
gi 2174213131  1015 VAINNNKGF 1023
Cdd:smart00119  320 LAINEGKGF 328
ATS1 COG5184
Alpha-tubulin suppressor ATS1 and related RCC1 domain-containing proteins [Cell cycle control, ...
 27-313 1.07e-63

Alpha-tubulin suppressor ATS1 and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton];


Pssm-ID: 444065 [Multi-domain]  Cd Length: 343  Bit Score: 219.46  E-value: 1.07e-63
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2174213131   27 ASGERHSLLLFSNHRVYSCGDNSRGQLGQKSPQSTKRPEPIQALSTVhIDlVSCGKEHSVAVCHQGRVFTWGAGSEGQLG 106
Cdd:COG5184      4 AAGGSHSCALKSDGTVWCWGDNSYGQLGDGTTTDRSTPVRVPGLSNV-VA-VAAGGDHTCALKADGTVWCWGNNSYGQLG 81

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2174213131  107 IGESkEISFMPTKINSLAGIKiiQVSCGHYHSLALSEDGQVFSWGSNRQGQLGLGNNLcSQASPQKV-KSLEGIplAQVA 185
Cdd:COG5184     82 DGTT-TDRTTPVKVPGLTGVV--AVAAGYYHSCALKSDGTVWCWGDNSSGQLGDGTTT-NRLTPVQVdAGLSGV--VAIA 155

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2174213131  186 AGGTHSFALSLMGTSFGWGNNRSGQLalsGNSAKEQIYKPHSIGALKtlNVVYISCGYEHTSVLTEDGQVFTFGGSSSEQ 265
Cdd:COG5184    156 AGGYHTCALKSDGTVWCWGANSYGQL---GDGTTTDRPTPVQVGGLS--GVVAVAAGGDHSCALKSDGTVWCWGSNSSGQ 230

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*...
gi 2174213131  266 LQHSPRSGRGGPQLIEGIGGhVSQIECGSYHTIAyVYTTGQVVSLGRG 313
Cdd:COG5184    231 LGDGTTTDRATPVQVAGLTG-VVAIAAGGSHTCA-LKSDGTVWCWGDN 276
HUL4 COG5021
Ubiquitin-protein ligase [Posttranslational modification, protein turnover, chaperones];
612-1023 1.19e-63

Ubiquitin-protein ligase [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 227354 [Multi-domain]  Cd Length: 872  Bit Score: 232.35  E-value: 1.19e-63
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2174213131  612 MNDIFNFNTEEGImaKQQMFFIKYYSMVFNDFPfildlPSKIILMKHDSSVKLSDEVKVAASPEKmgcPFFILKVRRSHL 691
Cdd:COG5021    455 LNNLYRFYFVEHR--KKTLTKNDSRLGSFISLN-----KLDIRRIKEDKRRKLFYSLKQKAKIFD---PYLHIKVRRDRV 524

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2174213131  692 VEDTLRQL-RQAEDfDLRKTLSVGFINEIRPEGGGVSSEFFHCIFEEMTDPKYEMFMYPENGSNMWFP-----VNPKfEK 765
Cdd:COG5021    525 FEDSYREImDESGD-DLKKTLEIEFVGEEGIDAGGLTREWLFLLSKEMFNPDYGLFEYITEDLYTLPInplssINPE-HL 602

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2174213131  766 SRYFLFGILCGLSLNNLNVINLSFPLALYKKLLEQKPSLEDLKDLSLLLGRNLQEVLNCE-AGVIEELHMYF--SIYWDQ 842
Cdd:COG5021    603 SYFKFLGRVIGKAIYDSRILDVQFSKAFYKKLLGKPVSLVDLESLDPELYRSLVWLLNNDiDETILDLTFTVedDSFGES 682

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2174213131  843 RDVDLIPDGISVPVNETNKRDYVSKCVDYIFNISIKTIYDEFHRGFYKVCNRDSIRHFQPEELMAAIIGNPTC-DWKQFE 921
Cdd:COG5021    683 RTVELIPNGRNISVTNENKKEYVKKVVDYKLNKRVEKQFSAFKSGFSEIIPPDLLQIFDESELELLIGGIPEDiDIDDWK 762

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2174213131  922 NNSKYeNGYSKSHPTILLFWKAFHELTLDEKKKFLLFLTGCDRLHV---KGLQ-NEGIRFRCPEVFSERDN--PRSLTCH 995
Cdd:COG5021    763 SNTAY-HGYTEDSPIIVWFWEIISEFDFEERAKLLQFVTGTSRIPIngfKDLQgSDGVRKFTIEKGGTDDDrlPSAHTCF 841

                          410       420
                   ....*....|....*....|....*...
gi 2174213131  996 SILDLPKYSTMRRMKEALQVAINNNKGF 1023
Cdd:COG5021    842 NRLKLPEYSSKEKLRSKLLTAINEGAGF 869
RCC1 pfam00415
Regulator of chromosome condensation (RCC1) repeat;
144-194 5.07e-17

Regulator of chromosome condensation (RCC1) repeat;


Pssm-ID: 395335 [Multi-domain]  Cd Length: 50  Bit Score: 75.63  E-value: 5.07e-17
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|.
gi 2174213131  144 DGQVFSWGSNRQGQLGLGNNlCSQASPQKVKSLEGIPLAQVAAGGTHSFAL 194
Cdd:pfam00415    1 DGRVYTWGRNDYGQLGLGTT-ENVLVPQKVEGLSGNKVVQVACGGDHTVAL 50
 
Name Accession Description Interval E-value
HECTc cd00078
HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It ...
 682-1023 1.31e-119

HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ubiquitin molecules to the end of growing ubiquitin chains.


Pssm-ID: 238033 [Multi-domain]  Cd Length: 352  Bit Score: 370.36  E-value: 1.31e-119
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2174213131  682 FILKVRRSHLVEDTLRQLRQAEDFDLRKTLSVGFINEIRPEGGGVSSEFFHCIFEEMTDPKYEMFMYPENGSN-MWFPVN 760
Cdd:cd00078      1 LKITVRRDRILEDALRQLSKVSSSDLKKVLEVEFVGEEGIDAGGVTREFFTLVSKELFNPSYGLFRYTPDDSGlLYPNPS 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2174213131  761 PKF---EKSRYFLFGILCGLSLNNLNVINLSFPLALYKKLLEQKPSLEDLKDLSLLLGRNLQEVLNCEaGVIEELHMYFS 837
Cdd:cd00078     81 SFAdedHLKLFRFLGRLLGKALYEGRLLDLPFSRAFYKKLLGKPLSLEDLEELDPELYKSLKELLDND-GDEDDLELTFT 159

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2174213131  838 I-----YWDQRDVDLIPDGISVPVNETNKRDYVSKCVDYIFNISIKTIYDEFHRGFYKVCNRDSIRHFQPEELMAAIIGN 912
Cdd:cd00078    160 IeldssFGGAVTVELKPGGRDIPVTNENKEEYVDLYVDYRLNKGIEEQVEAFRDGFSEVIPEELLSLFTPEELELLICGS 239

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2174213131  913 PTCDWKQFENNSKYENGYSKSHPTILLFWKAFHELTLDEKKKFLLFLTGCDRLHVKGLQNEGIRFRCPEVFSERDN-PRS 991
Cdd:cd00078    240 EDIDLEDLKKNTEYKGGYSSDSPTIQWFWEVLESFTNEERKKFLQFVTGSSRLPVGGFADLNPKFTIRRVGSPDDRlPTA 319

                          330       340       350
                   ....*....|....*....|....*....|..
gi 2174213131  992 LTCHSILDLPKYSTMRRMKEALQVAINNNKGF 1023
Cdd:cd00078    320 HTCFNLLKLPPYSSKEILREKLLYAINEGAGF 351
HECT pfam00632
HECT-domain (ubiquitin-transferase); The name HECT comes from Homologous to the E6-AP Carboxyl ...
 734-1023 3.51e-77

HECT-domain (ubiquitin-transferase); The name HECT comes from Homologous to the E6-AP Carboxyl Terminus.


Pssm-ID: 459880  Cd Length: 304  Bit Score: 255.23  E-value: 3.51e-77
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2174213131  734 IFEEMTDPKYEMFMYPENGSN-MWF----PVNPKFEKSRYF-LFGILCGLSLNNLNVINLSFPLALYKKLLEQKPSLEDL 807
Cdd:pfam00632    3 LSKELFDPNYGLFEYETEDDRtYWFnpssSESPDLELLDYFkFLGKLLGKAIYNGILLDLPFPPFFYKKLLGEPLTLEDL 82

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2174213131  808 KDLSLLLGRNLQEVLNCEAGVIEELHMYFSI--YWDQRDVDLIPDGISVPVNETNKRDYVSKCVDYIFNISIKTIYDEFH 885
Cdd:pfam00632   83 ESIDPELYKSLKSLLNMDNDDDEDLGLTFTIpvFGESKTIELIPNGRNIPVTNENKEEYIRLYVDYRLNKSIEPQLEAFR 162

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2174213131  886 RGFYKVCNRDSIRHFQPEELMAAIIGNPTCDWKQFENNSKYENGYSKSHPTILLFWKAFHELTLDEKKKFLLFLTGCDRL 965
Cdd:pfam00632  163 KGFYSVIPKEALSLFTPEELELLICGSPEIDVEDLKKNTEYDGGYTKNSPTIQWFWEILEEFSPEQRRLFLKFVTGSSRL 242

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 2174213131  966 HVKGLQN-EGIRFRCPEVFSERDNPRSLTCHSILDLPKYSTMRRMKEALQVAINNNKGF 1023
Cdd:pfam00632  243 PVGGFKSlPKFTIVRKGGDDDDRLPTAHTCFNRLKLPDYSSKEILKEKLLIAIEEGEGF 301
HECTc smart00119
Domain Homologous to E6-AP Carboxyl Terminus with; E3 ubiquitin-protein ligases. Can bind to ...
 706-1023 1.91e-76

Domain Homologous to E6-AP Carboxyl Terminus with; E3 ubiquitin-protein ligases. Can bind to E2 enzymes.


Pssm-ID: 214523  Cd Length: 328  Bit Score: 254.08  E-value: 1.91e-76
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2174213131   706 DLRK-TLSVGFINEIRPEGGGVSSEFFHCIFEEMTDPKYEMFMYPENGSNMWFPVNP---KFEKSRYFLF-GILCGLSLN 780
Cdd:smart00119    1 DLKKrVLEIEFEGEEGLDGGGVTREFFFLLSKELFNPDYGLFRYSPNDYLLYPNPRSgfaNEEHLSYFRFiGRVLGKALY 80

                            90       100       110       120       130       140       150       160
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2174213131   781 NLNVINLSFPLALYKKLLEQKPSLEDLKDLSLLLGRNLQEvLNCEAGVIEELHMYFSI-----YWDQRDVDLIPDGISVP 855
Cdd:smart00119   81 DNRLLDLFFARPFYKKLLGKPVTLHDLESLDPELYKSLKW-LLLNNDTSEELDLTFSIvltseFGQVKVVELKPGGSNIP 159

                           170       180       190       200       210       220       230       240
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2174213131   856 VNETNKRDYVSKCVDYIFNISIKTIYDEFHRGFYKVCNRDSIRHFQPEELMAAIIGNPTCDWKQFENNSKYENGYSKSHP 935
Cdd:smart00119  160 VTEENKKEYVHLVIEYRLNKGIEKQLEAFREGFSEVIPENLLKLFDPEELELLICGSPEIDVDDLKSNTEYKGGYSANSQ 239

                           250       260       270       280       290       300       310       320
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2174213131   936 TILLFWKAFHELTLDEKKKFLLFLTGCDRLHVKGLQNEGIRFRCPEVFSERDN-PRSLTCHSILDLPKYSTMRRMKEALQ 1014
Cdd:smart00119  240 TIKWFWEVVESFTNEERRKLLQFVTGSSRLPVGGFAALSPKFTIRKAGSDDERlPTAHTCFNRLKLPPYSSKEILREKLL 319


                    ....*....
gi 2174213131  1015 VAINNNKGF 1023
Cdd:smart00119  320 LAINEGKGF 328
ATS1 COG5184
Alpha-tubulin suppressor ATS1 and related RCC1 domain-containing proteins [Cell cycle control, ...
 27-313 1.07e-63

Alpha-tubulin suppressor ATS1 and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton];


Pssm-ID: 444065 [Multi-domain]  Cd Length: 343  Bit Score: 219.46  E-value: 1.07e-63
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2174213131   27 ASGERHSLLLFSNHRVYSCGDNSRGQLGQKSPQSTKRPEPIQALSTVhIDlVSCGKEHSVAVCHQGRVFTWGAGSEGQLG 106
Cdd:COG5184      4 AAGGSHSCALKSDGTVWCWGDNSYGQLGDGTTTDRSTPVRVPGLSNV-VA-VAAGGDHTCALKADGTVWCWGNNSYGQLG 81

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2174213131  107 IGESkEISFMPTKINSLAGIKiiQVSCGHYHSLALSEDGQVFSWGSNRQGQLGLGNNLcSQASPQKV-KSLEGIplAQVA 185
Cdd:COG5184     82 DGTT-TDRTTPVKVPGLTGVV--AVAAGYYHSCALKSDGTVWCWGDNSSGQLGDGTTT-NRLTPVQVdAGLSGV--VAIA 155

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2174213131  186 AGGTHSFALSLMGTSFGWGNNRSGQLalsGNSAKEQIYKPHSIGALKtlNVVYISCGYEHTSVLTEDGQVFTFGGSSSEQ 265
Cdd:COG5184    156 AGGYHTCALKSDGTVWCWGANSYGQL---GDGTTTDRPTPVQVGGLS--GVVAVAAGGDHSCALKSDGTVWCWGSNSSGQ 230

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*...
gi 2174213131  266 LQHSPRSGRGGPQLIEGIGGhVSQIECGSYHTIAyVYTTGQVVSLGRG 313
Cdd:COG5184    231 LGDGTTTDRATPVQVAGLTG-VVAIAAGGSHTCA-LKSDGTVWCWGDN 276
HUL4 COG5021
Ubiquitin-protein ligase [Posttranslational modification, protein turnover, chaperones];
612-1023 1.19e-63

Ubiquitin-protein ligase [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 227354 [Multi-domain]  Cd Length: 872  Bit Score: 232.35  E-value: 1.19e-63
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2174213131  612 MNDIFNFNTEEGImaKQQMFFIKYYSMVFNDFPfildlPSKIILMKHDSSVKLSDEVKVAASPEKmgcPFFILKVRRSHL 691
Cdd:COG5021    455 LNNLYRFYFVEHR--KKTLTKNDSRLGSFISLN-----KLDIRRIKEDKRRKLFYSLKQKAKIFD---PYLHIKVRRDRV 524

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2174213131  692 VEDTLRQL-RQAEDfDLRKTLSVGFINEIRPEGGGVSSEFFHCIFEEMTDPKYEMFMYPENGSNMWFP-----VNPKfEK 765
Cdd:COG5021    525 FEDSYREImDESGD-DLKKTLEIEFVGEEGIDAGGLTREWLFLLSKEMFNPDYGLFEYITEDLYTLPInplssINPE-HL 602

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2174213131  766 SRYFLFGILCGLSLNNLNVINLSFPLALYKKLLEQKPSLEDLKDLSLLLGRNLQEVLNCE-AGVIEELHMYF--SIYWDQ 842
Cdd:COG5021    603 SYFKFLGRVIGKAIYDSRILDVQFSKAFYKKLLGKPVSLVDLESLDPELYRSLVWLLNNDiDETILDLTFTVedDSFGES 682

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2174213131  843 RDVDLIPDGISVPVNETNKRDYVSKCVDYIFNISIKTIYDEFHRGFYKVCNRDSIRHFQPEELMAAIIGNPTC-DWKQFE 921
Cdd:COG5021    683 RTVELIPNGRNISVTNENKKEYVKKVVDYKLNKRVEKQFSAFKSGFSEIIPPDLLQIFDESELELLIGGIPEDiDIDDWK 762

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2174213131  922 NNSKYeNGYSKSHPTILLFWKAFHELTLDEKKKFLLFLTGCDRLHV---KGLQ-NEGIRFRCPEVFSERDN--PRSLTCH 995
Cdd:COG5021    763 SNTAY-HGYTEDSPIIVWFWEIISEFDFEERAKLLQFVTGTSRIPIngfKDLQgSDGVRKFTIEKGGTDDDrlPSAHTCF 841

                          410       420
                   ....*....|....*....|....*...
gi 2174213131  996 SILDLPKYSTMRRMKEALQVAINNNKGF 1023
Cdd:COG5021    842 NRLKLPEYSSKEKLRSKLLTAINEGAGF 869
ATS1 COG5184
Alpha-tubulin suppressor ATS1 and related RCC1 domain-containing proteins [Cell cycle control, ...
 12-313 2.02e-60

Alpha-tubulin suppressor ATS1 and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton];


Pssm-ID: 444065 [Multi-domain]  Cd Length: 343  Bit Score: 210.22  E-value: 2.02e-60
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2174213131   12 PRRLEAGTGLKllKAASGERHSLLLFSNHRVYSCGDNSRGQLGQksPQSTKRPEPIQALSTVHIDLVSCGKEHSVAVCHQ 91
Cdd:COG5184     41 PVRVPGLSNVV--AVAAGGDHTCALKADGTVWCWGNNSYGQLGD--GTTTDRTTPVKVPGLTGVVAVAAGYYHSCALKSD 116

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2174213131   92 GRVFTWGAGSEGQLGIGeSKEISFMPTKInSLAGIKIIQVSCGHYHSLALSEDGQVFSWGSNRQGQLGLGNNLcSQASPQ 171
Cdd:COG5184    117 GTVWCWGDNSSGQLGDG-TTTNRLTPVQV-DAGLSGVVAIAAGGYHTCALKSDGTVWCWGANSYGQLGDGTTT-DRPTPV 193

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2174213131  172 KVKSLEGIplAQVAAGGTHSFALSLMGTSFGWGNNRSGQLalsGNSAKEQIYKPHSIGALKtlNVVYISCGYEHTSVLTE 251
Cdd:COG5184    194 QVGGLSGV--VAVAAGGDHSCALKSDGTVWCWGSNSSGQL---GDGTTTDRATPVQVAGLT--GVVAIAAGGSHTCALKS 266

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2174213131  252 DGQVFTFGGSSSEQLQHSPRSGRGGPQLIEGIGGhVSQIECGSYHTIAYVyTTGQVV--------SLGRG 313
Cdd:COG5184    267 DGTVWCWGDNSYGQLGDGTTTDRSTPVKVPGLSG-VVAVAAGSSHTCALL-TDGTVWcwgdnaygQLGDG 334
ATS1 COG5184
Alpha-tubulin suppressor ATS1 and related RCC1 domain-containing proteins [Cell cycle control, ...
 27-278 1.40e-54

Alpha-tubulin suppressor ATS1 and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton];


Pssm-ID: 444065 [Multi-domain]  Cd Length: 343  Bit Score: 193.65  E-value: 1.40e-54
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2174213131   27 ASGERHSLLLFSNHRVYSCGDNSRGQLGQKSPQSTKRPEPIQA-LSTVhIDlVSCGKEHSVAVCHQGRVFTWGAGSEGQL 105
Cdd:COG5184    104 AAGYYHSCALKSDGTVWCWGDNSSGQLGDGTTTNRLTPVQVDAgLSGV-VA-IAAGGYHTCALKSDGTVWCWGANSYGQL 181

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2174213131  106 GIGESKEISfMPTKINSLAGIkiIQVSCGHYHSLALSEDGQVFSWGSNRQGQLGLGNNLcSQASPQKVKSLEGIplAQVA 185
Cdd:COG5184    182 GDGTTTDRP-TPVQVGGLSGV--VAVAAGGDHSCALKSDGTVWCWGSNSSGQLGDGTTT-DRATPVQVAGLTGV--VAIA 255

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2174213131  186 AGGTHSFALSLMGTSFGWGNNRSGQLalsGNSAKEQIYKPHSIGALKtlNVVYISCGYEHTSVLTEDGQVFTFGGSSSEQ 265
Cdd:COG5184    256 AGGSHTCALKSDGTVWCWGDNSYGQL---GDGTTTDRSTPVKVPGLS--GVVAVAAGSSHTCALLTDGTVWCWGDNAYGQ 330

                          250
                   ....*....|...
gi 2174213131  266 LQHSPRSGRGGPQ 278
Cdd:COG5184    331 LGDGTTTDRSTPV 343
ATS1 COG5184
Alpha-tubulin suppressor ATS1 and related RCC1 domain-containing proteins [Cell cycle control, ...
 78-315 2.85e-47

Alpha-tubulin suppressor ATS1 and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton];


Pssm-ID: 444065 [Multi-domain]  Cd Length: 343  Bit Score: 172.47  E-value: 2.85e-47
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2174213131   78 VSCGKEHSVAVCHQGRVFTWGAGSEGQLGIGESkEISFMPTKINSLAGIKiiQVSCGHYHSLALSEDGQVFSWGSNRQGQ 157
Cdd:COG5184      3 VAAGGSHSCALKSDGTVWCWGDNSYGQLGDGTT-TDRSTPVRVPGLSNVV--AVAAGGDHTCALKADGTVWCWGNNSYGQ 79

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2174213131  158 LGLGNNLcSQASPQKVKSLEGIplAQVAAGGTHSFALSLMGTSFGWGNNRSGQLalsGNSAKEQIYKPHSIGAlKTLNVV 237
Cdd:COG5184     80 LGDGTTT-DRTTPVKVPGLTGV--VAVAAGYYHSCALKSDGTVWCWGDNSSGQL---GDGTTTNRLTPVQVDA-GLSGVV 152

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2174213131  238 YISCGYEHTSVLTEDGQVFTFGGSSSEQLQHSPRSGRGGPQLIEGIGGhVSQIECGSYHTIAyVYTTGQVVSLGRGPS 315
Cdd:COG5184    153 AIAAGGYHTCALKSDGTVWCWGANSYGQLGDGTTTDRPTPVQVGGLSG-VVAVAAGGDHSCA-LKSDGTVWCWGSNSS 228
ATS1 COG5184
Alpha-tubulin suppressor ATS1 and related RCC1 domain-containing proteins [Cell cycle control, ...
 129-315 9.87e-36

Alpha-tubulin suppressor ATS1 and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton];


Pssm-ID: 444065 [Multi-domain]  Cd Length: 343  Bit Score: 138.96  E-value: 9.87e-36
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2174213131  129 IQVSCGHYHSLALSEDGQVFSWGSNRQGQLGLGNNLcSQASPQKVKSLEGIplAQVAAGGTHSFALSLMGTSFGWGNNRS 208
Cdd:COG5184      1 TQVAAGGSHSCALKSDGTVWCWGDNSYGQLGDGTTT-DRSTPVRVPGLSNV--VAVAAGGDHTCALKADGTVWCWGNNSY 77

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2174213131  209 GQLalsGNSAKEQIYKPHSIGALKtlNVVYISCGYEHTSVLTEDGQVFTFGGSSSEQLQHSPRSGRGGPQLIEGIGGHVS 288
Cdd:COG5184     78 GQL---GDGTTTDRTTPVKVPGLT--GVVAVAAGYYHSCALKSDGTVWCWGDNSSGQLGDGTTTNRLTPVQVDAGLSGVV 152

                          170       180
                   ....*....|....*....|....*..
gi 2174213131  289 QIECGSYHTIAyVYTTGQVVSLGRGPS 315
Cdd:COG5184    153 AIAAGGYHTCA-LKSDGTVWCWGANSY 178
ATS1 COG5184
Alpha-tubulin suppressor ATS1 and related RCC1 domain-containing proteins [Cell cycle control, ...
 7-171 2.79e-32

Alpha-tubulin suppressor ATS1 and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton];


Pssm-ID: 444065 [Multi-domain]  Cd Length: 343  Bit Score: 128.94  E-value: 2.79e-32
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2174213131    7 PGRRQPRRLEAGTGLKLLkaASGERHSLLLFSNHRVYSCGDNSRGQLGQKSPQSTKRPEPIQALSTVhIDlVSCGKEHSV 86
Cdd:COG5184    187 TDRPTPVQVGGLSGVVAV--AAGGDHSCALKSDGTVWCWGSNSSGQLGDGTTTDRATPVQVAGLTGV-VA-IAAGGSHTC 262

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2174213131   87 AVCHQGRVFTWGAGSEGQLGIGeSKEISFMPTKINSLAGIkiIQVSCGHYHSLALSEDGQVFSWGSNRQGQLGLGNNLcS 166
Cdd:COG5184    263 ALKSDGTVWCWGDNSYGQLGDG-TTTDRSTPVKVPGLSGV--VAVAAGSSHTCALLTDGTVWCWGDNAYGQLGDGTTT-D 338


                   ....*
gi 2174213131  167 QASPQ 171
Cdd:COG5184    339 RSTPV 343
RCC1 pfam00415
Regulator of chromosome condensation (RCC1) repeat;
144-194 5.07e-17

Regulator of chromosome condensation (RCC1) repeat;


Pssm-ID: 395335 [Multi-domain]  Cd Length: 50  Bit Score: 75.63  E-value: 5.07e-17
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|.
gi 2174213131  144 DGQVFSWGSNRQGQLGLGNNlCSQASPQKVKSLEGIPLAQVAAGGTHSFAL 194
Cdd:pfam00415    1 DGRVYTWGRNDYGQLGLGTT-ENVLVPQKVEGLSGNKVVQVACGGDHTVAL 50
RCC1 pfam00415
Regulator of chromosome condensation (RCC1) repeat;
92-141 1.24e-16

Regulator of chromosome condensation (RCC1) repeat;


Pssm-ID: 395335 [Multi-domain]  Cd Length: 50  Bit Score: 74.48  E-value: 1.24e-16
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|
gi 2174213131   92 GRVFTWGAGSEGQLGIGeSKEISFMPTKINSLAGIKIIQVSCGHYHSLAL 141
Cdd:pfam00415    2 GRVYTWGRNDYGQLGLG-TTENVLVPQKVEGLSGNKVVQVACGGDHTVAL 50
RCC1 pfam00415
Regulator of chromosome condensation (RCC1) repeat;
39-88 9.84e-11

Regulator of chromosome condensation (RCC1) repeat;


Pssm-ID: 395335 [Multi-domain]  Cd Length: 50  Bit Score: 57.91  E-value: 9.84e-11
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|
gi 2174213131   39 NHRVYSCGDNSRGQLGQKSPQSTKRPEPIQALSTVHIDLVSCGKEHSVAV 88
Cdd:pfam00415    1 DGRVYTWGRNDYGQLGLGTTENVLVPQKVEGLSGNKVVQVACGGDHTVAL 50
RCC1_2 pfam13540
Regulator of chromosome condensation (RCC1) repeat;
128-157 1.53e-10

Regulator of chromosome condensation (RCC1) repeat;


Pssm-ID: 463914 [Multi-domain]  Cd Length: 30  Bit Score: 56.66  E-value: 1.53e-10
                           10        20        30
                   ....*....|....*....|....*....|
gi 2174213131  128 IIQVSCGHYHSLALSEDGQVFSWGSNRQGQ 157
Cdd:pfam13540    1 VVSVAAGDNHTLALTSDGRVYCWGDNSYGQ 30
RCC1 pfam00415
Regulator of chromosome condensation (RCC1) repeat;
252-299 2.50e-07

Regulator of chromosome condensation (RCC1) repeat;


Pssm-ID: 395335 [Multi-domain]  Cd Length: 50  Bit Score: 48.28  E-value: 2.50e-07
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*....
gi 2174213131  252 DGQVFTFGGSSSEQLQHSPRSGRGGPQLIEGIGG-HVSQIECGSYHTIA 299
Cdd:pfam00415    1 DGRVYTWGRNDYGQLGLGTTENVLVPQKVEGLSGnKVVQVACGGDHTVA 49
RCC1_2 pfam13540
Regulator of chromosome condensation (RCC1) repeat;
27-52 2.04e-05

Regulator of chromosome condensation (RCC1) repeat;


Pssm-ID: 463914 [Multi-domain]  Cd Length: 30  Bit Score: 42.03  E-value: 2.04e-05
                           10        20
                   ....*....|....*....|....*.
gi 2174213131   27 ASGERHSLLLFSNHRVYSCGDNSRGQ 52
Cdd:pfam13540    5 AAGDNHTLALTSDGRVYCWGDNSYGQ 30
RCC1_2 pfam13540
Regulator of chromosome condensation (RCC1) repeat;
182-210 7.09e-05

Regulator of chromosome condensation (RCC1) repeat;


Pssm-ID: 463914 [Multi-domain]  Cd Length: 30  Bit Score: 40.49  E-value: 7.09e-05
                           10        20
                   ....*....|....*....|....*....
gi 2174213131  182 AQVAAGGTHSFALSLMGTSFGWGNNRSGQ 210
Cdd:pfam13540    2 VSVAAGDNHTLALTSDGRVYCWGDNSYGQ 30
RCC1_2 pfam13540
Regulator of chromosome condensation (RCC1) repeat;
236-265 7.44e-05

Regulator of chromosome condensation (RCC1) repeat;


Pssm-ID: 463914 [Multi-domain]  Cd Length: 30  Bit Score: 40.49  E-value: 7.44e-05
                           10        20        30
                   ....*....|....*....|....*....|
gi 2174213131  236 VVYISCGYEHTSVLTEDGQVFTFGGSSSEQ 265
Cdd:pfam13540    1 VVSVAAGDNHTLALTSDGRVYCWGDNSYGQ 30
RCC1_2 pfam13540
Regulator of chromosome condensation (RCC1) repeat;
75-104 1.02e-04

Regulator of chromosome condensation (RCC1) repeat;


Pssm-ID: 463914 [Multi-domain]  Cd Length: 30  Bit Score: 40.10  E-value: 1.02e-04
                           10        20        30
                   ....*....|....*....|....*....|
gi 2174213131   75 IDLVSCGKEHSVAVCHQGRVFTWGAGSEGQ 104
Cdd:pfam13540    1 VVSVAAGDNHTLALTSDGRVYCWGDNSYGQ 30
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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