H/ACA ribonucleoprotein complex subunit 1 [Rattus norvegicus]
H/ACA ribonucleoprotein complex subunit GAR1/NAF1( domain architecture ID 10516561)
H/ACA ribonucleoprotein complex subunit GAR1/NAF1 is an RNA-binding protein required for the maturation of box H/ACA snoRNPs complex and ribosome biogenesis, as well as telomere maintenance
List of domain hits
Name | Accession | Description | Interval | E-value | |||
Gar1 | pfam04410 | Gar1/Naf1 RNA binding region; Gar1 is a small nucleolar RNP that is required for pre-mRNA ... |
72-160 | 7.33e-33 | |||
Gar1/Naf1 RNA binding region; Gar1 is a small nucleolar RNP that is required for pre-mRNA processing and pseudouridylation. It is co-immunoprecipitated with the H/ACA families of snoRNAs. This family represents the conserved central region of Gar1. This region is necessary and sufficient for normal cell growth, and specifically binds two snoRNAs snR10 and snR30. This region is also necessary for nucleolar targeting, and it is thought that the protein is co-transported to the nucleolus as part of a nucleoprotein complex. In humans, Gar1 is also component of telomerase in vivo. Naf1 is an essential protein that plays a role in ribosome biogenesis, modification of spliceosomal small nuclear RNAs and telomere synthesis, and is homologous to Gar1. : Pssm-ID: 461296 Cd Length: 89 Bit Score: 114.12 E-value: 7.33e-33
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Name | Accession | Description | Interval | E-value | |||
Gar1 | pfam04410 | Gar1/Naf1 RNA binding region; Gar1 is a small nucleolar RNP that is required for pre-mRNA ... |
72-160 | 7.33e-33 | |||
Gar1/Naf1 RNA binding region; Gar1 is a small nucleolar RNP that is required for pre-mRNA processing and pseudouridylation. It is co-immunoprecipitated with the H/ACA families of snoRNAs. This family represents the conserved central region of Gar1. This region is necessary and sufficient for normal cell growth, and specifically binds two snoRNAs snR10 and snR30. This region is also necessary for nucleolar targeting, and it is thought that the protein is co-transported to the nucleolus as part of a nucleoprotein complex. In humans, Gar1 is also component of telomerase in vivo. Naf1 is an essential protein that plays a role in ribosome biogenesis, modification of spliceosomal small nuclear RNAs and telomere synthesis, and is homologous to Gar1. Pssm-ID: 461296 Cd Length: 89 Bit Score: 114.12 E-value: 7.33e-33
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GAR1 | COG3277 | rRNA processing protein Gar1 [Translation, ribosomal structure and biogenesis]; rRNA ... |
75-149 | 6.09e-05 | |||
rRNA processing protein Gar1 [Translation, ribosomal structure and biogenesis]; rRNA processing protein Gar1 is part of the Pathway/BioSystem: 16S rRNA modification Pssm-ID: 442508 Cd Length: 76 Bit Score: 40.25 E-value: 6.09e-05
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PRK13149 | PRK13149 | H/ACA RNA-protein complex component Gar1; Reviewed |
95-149 | 2.35e-03 | |||
H/ACA RNA-protein complex component Gar1; Reviewed Pssm-ID: 183872 Cd Length: 73 Bit Score: 35.64 E-value: 2.35e-03
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Name | Accession | Description | Interval | E-value | |||
Gar1 | pfam04410 | Gar1/Naf1 RNA binding region; Gar1 is a small nucleolar RNP that is required for pre-mRNA ... |
72-160 | 7.33e-33 | |||
Gar1/Naf1 RNA binding region; Gar1 is a small nucleolar RNP that is required for pre-mRNA processing and pseudouridylation. It is co-immunoprecipitated with the H/ACA families of snoRNAs. This family represents the conserved central region of Gar1. This region is necessary and sufficient for normal cell growth, and specifically binds two snoRNAs snR10 and snR30. This region is also necessary for nucleolar targeting, and it is thought that the protein is co-transported to the nucleolus as part of a nucleoprotein complex. In humans, Gar1 is also component of telomerase in vivo. Naf1 is an essential protein that plays a role in ribosome biogenesis, modification of spliceosomal small nuclear RNAs and telomere synthesis, and is homologous to Gar1. Pssm-ID: 461296 Cd Length: 89 Bit Score: 114.12 E-value: 7.33e-33
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GAR1 | COG3277 | rRNA processing protein Gar1 [Translation, ribosomal structure and biogenesis]; rRNA ... |
75-149 | 6.09e-05 | |||
rRNA processing protein Gar1 [Translation, ribosomal structure and biogenesis]; rRNA processing protein Gar1 is part of the Pathway/BioSystem: 16S rRNA modification Pssm-ID: 442508 Cd Length: 76 Bit Score: 40.25 E-value: 6.09e-05
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PRK13149 | PRK13149 | H/ACA RNA-protein complex component Gar1; Reviewed |
95-149 | 2.35e-03 | |||
H/ACA RNA-protein complex component Gar1; Reviewed Pssm-ID: 183872 Cd Length: 73 Bit Score: 35.64 E-value: 2.35e-03
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Blast search parameters | ||||
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