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Conserved domains on  [gi|318104865|ref|NP_001099385|]
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N-acetylserotonin O-methyltransferase-like protein [Rattus norvegicus]

Protein Classification

nucleoside triphosphate pyrophosphatase( domain architecture ID 10088068)

Maf family nucleoside triphosphate (NTP) pyrophosphatase hydrolyzes nucleotides to their respective monophosphates

CATH:  3.90.950.10
EC:  3.6.1.-
Gene Ontology:  GO:0047429|GO:0009146|GO:0000166
PubMed:  8387996
SCOP:  4000518

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
Maf cd00555
Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in ...
 15-209 6.79e-69

Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea, but homologs in B.subtilis and S.cerevisiae are nonessential for cell division. Maf has been predicted to be a nucleotide- or nucleic acid-binding protein with structural similarity to the hypoxanthine/xanthine NTP pyrophosphatase Ham1 from Methanococcus jannaschii, RNase H from Escherichia coli, and some other nucleotide or RNA-binding proteins.


:

Pssm-ID: 238310  Cd Length: 180  Bit Score: 208.87  E-value: 6.79e-69
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 318104865  15 VVLASASPRRREILDLAGVVFDVIPSHFSEVPPPEHLlrPQDLVIANAKGKALDVgmrLSQADPEtqHLIIGADTIVAME 94
Cdd:cd00555    1 LILASASPRRRELLEQLGIPFEVVPSDIDETPIKGES--PEDYVLRLAEAKAEAV---AARLPPD--ALVIGADTVVVLD 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 318104865  95 GQIMGKPCDREDALRMLTRLNGREHSVITGVAIIltggagtRDAEVVVVFHEETLVTFSKLSDELVQEHVEGGEPWDKAG 174
Cdd:cd00555   74 GRILGKPKDREEAREMLKRLSGRTHEVYTGVALI-------DPGGKLVTDVESTKVRFRELSDEEIEAYVASGEPLDKAG 146

                        170       180       190
                 ....*....|....*....|....*....|....*
gi 318104865 175 GYGLQARGGAIMaEAVRGDPLNAAGLPLNRLCREL 209
Cdd:cd00555  147 AYGIQGLGGALI-ERIEGDYSNVVGLPLPELLKLL 180
 
Name Accession Description Interval E-value
Maf cd00555
Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in ...
 15-209 6.79e-69

Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea, but homologs in B.subtilis and S.cerevisiae are nonessential for cell division. Maf has been predicted to be a nucleotide- or nucleic acid-binding protein with structural similarity to the hypoxanthine/xanthine NTP pyrophosphatase Ham1 from Methanococcus jannaschii, RNase H from Escherichia coli, and some other nucleotide or RNA-binding proteins.


Pssm-ID: 238310  Cd Length: 180  Bit Score: 208.87  E-value: 6.79e-69
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 318104865  15 VVLASASPRRREILDLAGVVFDVIPSHFSEVPPPEHLlrPQDLVIANAKGKALDVgmrLSQADPEtqHLIIGADTIVAME 94
Cdd:cd00555    1 LILASASPRRRELLEQLGIPFEVVPSDIDETPIKGES--PEDYVLRLAEAKAEAV---AARLPPD--ALVIGADTVVVLD 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 318104865  95 GQIMGKPCDREDALRMLTRLNGREHSVITGVAIIltggagtRDAEVVVVFHEETLVTFSKLSDELVQEHVEGGEPWDKAG 174
Cdd:cd00555   74 GRILGKPKDREEAREMLKRLSGRTHEVYTGVALI-------DPGGKLVTDVESTKVRFRELSDEEIEAYVASGEPLDKAG 146

                        170       180       190
                 ....*....|....*....|....*....|....*
gi 318104865 175 GYGLQARGGAIMaEAVRGDPLNAAGLPLNRLCREL 209
Cdd:cd00555  147 AYGIQGLGGALI-ERIEGDYSNVVGLPLPELLKLL 180
Maf COG0424
7-methyl-GTP pyrophosphatase and related NTP pyrophosphatases, Maf/HAM1 superfamily [Secondary ...
 13-209 1.62e-66

7-methyl-GTP pyrophosphatase and related NTP pyrophosphatases, Maf/HAM1 superfamily [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 440193  Cd Length: 189  Bit Score: 203.35  E-value: 1.62e-66
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 318104865  13 YHVVLASASPRRREILDLAGVVFDVIPSHFSEVPPPEhlLRPQDLVIANAKGKALDVGMRLSQAdpetqhLIIGADTIVA 92
Cdd:COG0424    1 PKLILASASPRRRELLEQLGLPFEVVPPDIDETPLPG--ESPEELVLRLARAKAEAVAARLPDA------LVLGADTVVV 72

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 318104865  93 MEGQIMGKPCDREDALRMLTRLNGREHSVITGVAIIltggagtRDAEVVVVFHEETLVTFSKLSDELVQEHVEGGEPWDK 172
Cdd:COG0424   73 LDGRILGKPADAEEARAMLRRLSGRTHRVHTGVALI-------DPGGRLWTRVVTTRVTFRPLSDAEIEAYLATGEPLDK 145

                        170       180       190
                 ....*....|....*....|....*....|....*..
gi 318104865 173 AGGYGLQARGGAIMaEAVRGDPLNAAGLPLNRLCREL 209
Cdd:COG0424  146 AGAYGIQGLGAALV-ERIEGSYSNVVGLPLIELLELL 181
Maf pfam02545
Maf-like protein; Maf is a putative inhibitor of septum formation in eukaryotes, bacteria, and ...
 15-209 5.89e-66

Maf-like protein; Maf is a putative inhibitor of septum formation in eukaryotes, bacteria, and archaea.


Pssm-ID: 460586  Cd Length: 174  Bit Score: 201.48  E-value: 5.89e-66
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 318104865   15 VVLASASPRRREILDLAGVVFDVIPSHFSEVPPPEhLLRPQDLVIANAKGKALDVgmrlsqadpetqhlIIGADTIVAMe 94
Cdd:pfam02545   1 LILASASPRRRELLEQLGIEFEVVPSDIDETPLKE-DPAPEEYVLRLARAKAEAL--------------VIGADTVVVL- 64

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 318104865   95 gqIMGKPCDREDALRMLTRLNGREHSVITGVAIILTGGAGTRdaevvVVFHEETLVTFSKLSDELVQEHVEGGEPWDKAG 174
Cdd:pfam02545  65 --ILGKPKDEEEARAMLKRLSGRTHEVYTGVALINPGGGTGG-----VSFVETTRVTFRPLSDEEIEAYVATGEPLDKAG 137

                         170       180       190
                  ....*....|....*....|....*....|....*
gi 318104865  175 GYGLQARGGAIMaEAVRGDPLNAAGLPLNRLCREL 209
Cdd:pfam02545 138 AYGIQGLGAALV-ERIEGDYSNVVGLPLIELLRLL 171
PRK00648 PRK00648
Maf-like protein; Reviewed
 13-209 7.28e-55

Maf-like protein; Reviewed


Pssm-ID: 234807  Cd Length: 191  Bit Score: 173.55  E-value: 7.28e-55
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 318104865  13 YHVVLASASPRRREILDLAGVVFDVIPSHFSEVPPPEHLLR---PQDLvianAKGKALDVgmrLSQADPETqhLIIGADT 89
Cdd:PRK00648   3 YKIILASSSPRRKEILEGFRIPFEVVPSPFVEESYPYSLDPeeiTLEL----ARLKAEAV---RSDLFPDE--LIITADT 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 318104865  90 IVAMEGQIMGKPCDREDALRMLTRLNGREHSVITGVAIIltggagTRDAEvvVVFHEETLVTFSKLSDELVQEHVEGGEP 169
Cdd:PRK00648  74 IVWYDGKVLGKPKDEEEAVEMLRTLSGKTHEVITGVCLL------HNGKL--LSGSETTQVTFRELSDEEIEYYIDTYKP 145

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
gi 318104865 170 WDKAGGYGLQARGGAIMaEAVRGDPLNAAGLPLNRLCREL 209
Cdd:PRK00648 146 LDKAGAYGIQEWGGLIV-KKIEGSYYNVMGLPIQTLYEEL 184
maf TIGR00172
MAF protein; This nonessential gene causes inhibition of septation when overexpressed. A ...
 13-209 1.68e-49

MAF protein; This nonessential gene causes inhibition of septation when overexpressed. A member of the family is found in the Archaeon Pyrococcus horikoshii and another in the round worm Caenorhabditis elegans. [Cellular processes, Cell division]


Pssm-ID: 129276  Cd Length: 183  Bit Score: 159.87  E-value: 1.68e-49
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 318104865   13 YHVVLASASPRRREILDLAGVVFDVIPSHFSEVPPPEHllRPQDLVIANAKGKALDVgmrlsqADPETQHLIIGADTIVA 92
Cdd:TIGR00172   3 KELILASQSPRRKELLEELGISFEQIVSEFDEKSLKTT--SPRELVYRLAKEKAQAV------AELLADALIIGADTVVI 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 318104865   93 MEGQIMGKPCDREDALRMLTRLNGREHSVITGVAIIltggagtrDAEVVVVFHEETLVTFSKLSDELVQEHVEGGEPWDK 172
Cdd:TIGR00172  75 LDGEIYGKPKDKEEAAEFLRKLSGQEHEVYTAVALI--------DSVHLLTFLDVTKVHFRALDPEEIEKYVESGEPLEK 146

                         170       180       190
                  ....*....|....*....|....*....|....*..
gi 318104865  173 AGGYGLQARGGaIMAEAVRGDPLNAAGLPLNRLCREL 209
Cdd:TIGR00172 147 AGAFGIEGFGA-PLIKKIDGDYSNVVGLPLEKLLGAL 182
 
Name Accession Description Interval E-value
Maf cd00555
Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in ...
 15-209 6.79e-69

Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea, but homologs in B.subtilis and S.cerevisiae are nonessential for cell division. Maf has been predicted to be a nucleotide- or nucleic acid-binding protein with structural similarity to the hypoxanthine/xanthine NTP pyrophosphatase Ham1 from Methanococcus jannaschii, RNase H from Escherichia coli, and some other nucleotide or RNA-binding proteins.


Pssm-ID: 238310  Cd Length: 180  Bit Score: 208.87  E-value: 6.79e-69
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 318104865  15 VVLASASPRRREILDLAGVVFDVIPSHFSEVPPPEHLlrPQDLVIANAKGKALDVgmrLSQADPEtqHLIIGADTIVAME 94
Cdd:cd00555    1 LILASASPRRRELLEQLGIPFEVVPSDIDETPIKGES--PEDYVLRLAEAKAEAV---AARLPPD--ALVIGADTVVVLD 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 318104865  95 GQIMGKPCDREDALRMLTRLNGREHSVITGVAIIltggagtRDAEVVVVFHEETLVTFSKLSDELVQEHVEGGEPWDKAG 174
Cdd:cd00555   74 GRILGKPKDREEAREMLKRLSGRTHEVYTGVALI-------DPGGKLVTDVESTKVRFRELSDEEIEAYVASGEPLDKAG 146

                        170       180       190
                 ....*....|....*....|....*....|....*
gi 318104865 175 GYGLQARGGAIMaEAVRGDPLNAAGLPLNRLCREL 209
Cdd:cd00555  147 AYGIQGLGGALI-ERIEGDYSNVVGLPLPELLKLL 180
Maf COG0424
7-methyl-GTP pyrophosphatase and related NTP pyrophosphatases, Maf/HAM1 superfamily [Secondary ...
 13-209 1.62e-66

7-methyl-GTP pyrophosphatase and related NTP pyrophosphatases, Maf/HAM1 superfamily [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 440193  Cd Length: 189  Bit Score: 203.35  E-value: 1.62e-66
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 318104865  13 YHVVLASASPRRREILDLAGVVFDVIPSHFSEVPPPEhlLRPQDLVIANAKGKALDVGMRLSQAdpetqhLIIGADTIVA 92
Cdd:COG0424    1 PKLILASASPRRRELLEQLGLPFEVVPPDIDETPLPG--ESPEELVLRLARAKAEAVAARLPDA------LVLGADTVVV 72

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 318104865  93 MEGQIMGKPCDREDALRMLTRLNGREHSVITGVAIIltggagtRDAEVVVVFHEETLVTFSKLSDELVQEHVEGGEPWDK 172
Cdd:COG0424   73 LDGRILGKPADAEEARAMLRRLSGRTHRVHTGVALI-------DPGGRLWTRVVTTRVTFRPLSDAEIEAYLATGEPLDK 145

                        170       180       190
                 ....*....|....*....|....*....|....*..
gi 318104865 173 AGGYGLQARGGAIMaEAVRGDPLNAAGLPLNRLCREL 209
Cdd:COG0424  146 AGAYGIQGLGAALV-ERIEGSYSNVVGLPLIELLELL 181
Maf pfam02545
Maf-like protein; Maf is a putative inhibitor of septum formation in eukaryotes, bacteria, and ...
 15-209 5.89e-66

Maf-like protein; Maf is a putative inhibitor of septum formation in eukaryotes, bacteria, and archaea.


Pssm-ID: 460586  Cd Length: 174  Bit Score: 201.48  E-value: 5.89e-66
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 318104865   15 VVLASASPRRREILDLAGVVFDVIPSHFSEVPPPEhLLRPQDLVIANAKGKALDVgmrlsqadpetqhlIIGADTIVAMe 94
Cdd:pfam02545   1 LILASASPRRRELLEQLGIEFEVVPSDIDETPLKE-DPAPEEYVLRLARAKAEAL--------------VIGADTVVVL- 64

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 318104865   95 gqIMGKPCDREDALRMLTRLNGREHSVITGVAIILTGGAGTRdaevvVVFHEETLVTFSKLSDELVQEHVEGGEPWDKAG 174
Cdd:pfam02545  65 --ILGKPKDEEEARAMLKRLSGRTHEVYTGVALINPGGGTGG-----VSFVETTRVTFRPLSDEEIEAYVATGEPLDKAG 137

                         170       180       190
                  ....*....|....*....|....*....|....*
gi 318104865  175 GYGLQARGGAIMaEAVRGDPLNAAGLPLNRLCREL 209
Cdd:pfam02545 138 AYGIQGLGAALV-ERIEGDYSNVVGLPLIELLRLL 171
PRK00648 PRK00648
Maf-like protein; Reviewed
 13-209 7.28e-55

Maf-like protein; Reviewed


Pssm-ID: 234807  Cd Length: 191  Bit Score: 173.55  E-value: 7.28e-55
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 318104865  13 YHVVLASASPRRREILDLAGVVFDVIPSHFSEVPPPEHLLR---PQDLvianAKGKALDVgmrLSQADPETqhLIIGADT 89
Cdd:PRK00648   3 YKIILASSSPRRKEILEGFRIPFEVVPSPFVEESYPYSLDPeeiTLEL----ARLKAEAV---RSDLFPDE--LIITADT 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 318104865  90 IVAMEGQIMGKPCDREDALRMLTRLNGREHSVITGVAIIltggagTRDAEvvVVFHEETLVTFSKLSDELVQEHVEGGEP 169
Cdd:PRK00648  74 IVWYDGKVLGKPKDEEEAVEMLRTLSGKTHEVITGVCLL------HNGKL--LSGSETTQVTFRELSDEEIEYYIDTYKP 145

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
gi 318104865 170 WDKAGGYGLQARGGAIMaEAVRGDPLNAAGLPLNRLCREL 209
Cdd:PRK00648 146 LDKAGAYGIQEWGGLIV-KKIEGSYYNVMGLPIQTLYEEL 184
maf TIGR00172
MAF protein; This nonessential gene causes inhibition of septation when overexpressed. A ...
 13-209 1.68e-49

MAF protein; This nonessential gene causes inhibition of septation when overexpressed. A member of the family is found in the Archaeon Pyrococcus horikoshii and another in the round worm Caenorhabditis elegans. [Cellular processes, Cell division]


Pssm-ID: 129276  Cd Length: 183  Bit Score: 159.87  E-value: 1.68e-49
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 318104865   13 YHVVLASASPRRREILDLAGVVFDVIPSHFSEVPPPEHllRPQDLVIANAKGKALDVgmrlsqADPETQHLIIGADTIVA 92
Cdd:TIGR00172   3 KELILASQSPRRKELLEELGISFEQIVSEFDEKSLKTT--SPRELVYRLAKEKAQAV------AELLADALIIGADTVVI 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 318104865   93 MEGQIMGKPCDREDALRMLTRLNGREHSVITGVAIIltggagtrDAEVVVVFHEETLVTFSKLSDELVQEHVEGGEPWDK 172
Cdd:TIGR00172  75 LDGEIYGKPKDKEEAAEFLRKLSGQEHEVYTAVALI--------DSVHLLTFLDVTKVHFRALDPEEIEKYVESGEPLEK 146

                         170       180       190
                  ....*....|....*....|....*....|....*..
gi 318104865  173 AGGYGLQARGGaIMAEAVRGDPLNAAGLPLNRLCREL 209
Cdd:TIGR00172 147 AGAFGIEGFGA-PLIKKIDGDYSNVVGLPLEKLLGAL 182
PRK00078 PRK00078
Maf-like protein; Reviewed
 15-205 1.73e-48

Maf-like protein; Reviewed


Pssm-ID: 234618  Cd Length: 192  Bit Score: 157.58  E-value: 1.73e-48
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 318104865  15 VVLASASPRRREILDLAGVVFDVIPSHFSE--VPPPEHLlrpQDLVIANAKGKALDVGMRLSQADPetqhLIIGADTIVA 92
Cdd:PRK00078   3 IILASASERRQELLKRILEDFQVIVSDFDEssVPFKGNI---ESYVMNLAEGKARSVSKKLDQESS----IVIGCDTIVA 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 318104865  93 MEGQIMGKPCDREDALRMLTRLNGREHSVITGVAIIltggaGTRDAEVVVVFhEETLVTFSKLSDELVQEHVEGGEPWDK 172
Cdd:PRK00078  76 FNGKVLGKPKDEEDAFEMLKALSGNEHEVYSGIAIL-----DTKSNKIIKDF-VCTEVKFSKLTDRQIRKYINTGEPMDK 149

                        170       180       190
                 ....*....|....*....|....*....|...
gi 318104865 173 AGGYGLQARGGaIMAEAVRGDPLNAAGLPLNRL 205
Cdd:PRK00078 150 AGAYGIQGKGG-VFVEEINGCYYNVVGLPLNKL 181
PRK14368 PRK14368
Maf-like protein; Provisional
 15-211 1.98e-44

Maf-like protein; Provisional


Pssm-ID: 237693  Cd Length: 193  Bit Score: 147.23  E-value: 1.98e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 318104865  15 VVLASASPRRREILDLAGVVFDVIPSHFSEVPPPEHllRPQDLVIANAKGKALDVGMRlsqadpETQHLIIGADTIVAME 94
Cdd:PRK14368   7 IVLASASPRRSELLASAGIEFDVVPADIPEEPLPGE--EPVDHVLRLAREKARAAAAL------AEGRFFIGADTIVVCD 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 318104865  95 GQIMGKPCDREDALRMLTRLNGREHSVITGVAIIltggagTRDAEVVVVFHEETLVTFSKLSDELVQEHVEGGEPWDKAG 174
Cdd:PRK14368  79 GEIMGKPKDEADAVRMLKKLSGVPHEVITGFAVY------DRERDGCVTKAVRTKVFFKPLRDEEIRDYIATGCPMDKAG 152

                        170       180       190
                 ....*....|....*....|....*....|....*..
gi 318104865 175 GYGLQArGGAIMAEAVRGDPLNAAGLPLNRLCRELGR 211
Cdd:PRK14368 153 AYAIQG-GAAHMVRKIDGSYTNVVGLPLCEVVEALRT 188
PRK14365 PRK14365
Maf-like protein; Provisional
 15-205 2.29e-43

Maf-like protein; Provisional


Pssm-ID: 237690  Cd Length: 197  Bit Score: 144.58  E-value: 2.29e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 318104865  15 VVLASASPRRREIL-DLAGVVFDVIPSHFSEVPPPEhlLRPQDLVIANAKGKALDVGMRLSQAdpetqhLIIGADTIVAM 93
Cdd:PRK14365   4 IILASASPRRKELLkQLIGDNFLVYPSSYEEPPQPG--LDPEELLLKHSLEKARDVAKHFDSG------IIISADTSVFC 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 318104865  94 EGQIMGKPCDREDALRMLTRLNGREHSVITGVAII-LTGGAGTRDaevvvvfHEETLVTFSKLSDELVQEHVEGGEPWDK 172
Cdd:PRK14365  76 NGEVLGKPASPENAEEMLEKLSGRKFLVITGLTVLdLDSGKEISE-------IESTDVWMTELSREQILAYVRTGEPLDK 148

                        170       180       190
                 ....*....|....*....|....*....|...
gi 318104865 173 AGGYGLQARgGAIMAEAVRGDPLNAAGLPLNRL 205
Cdd:PRK14365 149 AGAFAIQGK-GAVLVEKIEGDFFNVVGLPLFRL 180
PRK14362 PRK14362
Maf-like protein; Provisional
 2-217 7.43e-42

Maf-like protein; Provisional


Pssm-ID: 172838  Cd Length: 207  Bit Score: 141.15  E-value: 7.43e-42
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 318104865   2 ALKPLAPLLRgyhVVLASASPRRREILDLAGVVFDVIPSHFSEvPPPEHLLRPQDLVIANAKGKALDVGMRLSQAdpetq 81
Cdd:PRK14362   4 STGPFTAACP---VVLASGSPRRREFLEQMGLPFEVILPGAAE-PSPIEGEQPEAYARRAAEAKARAVAADHAGR----- 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 318104865  82 hLIIGADTIVAMEGQIMGKPCDREDALRMLTRLNGREHSVITGVAIILTGGAGtrdaevvVVFHEETLVTFSKLSDELVQ 161
Cdd:PRK14362  75 -LVIAADTVVALDGMILGKPADRADALSMLRRLAGRTHEVVSACCVVLPDGGR-------EVFHAITRVTMWDWPEAALA 146

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 318104865 162 EHVEGGEPWDKAGGYGLQARgGAIMAEAVRGDPLNAAGLPLNRLCRELGRR--LLPSG 217
Cdd:PRK14362 147 AYVATGEPSDKAGAYGIQGI-GAFLVRSIEGSWSNVVGLPVAELTALLLRRgvILPVG 203
PRK14363 PRK14363
Maf-like protein; Provisional
 13-202 3.83e-35

Maf-like protein; Provisional


Pssm-ID: 184647  Cd Length: 204  Bit Score: 123.85  E-value: 3.83e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 318104865  13 YHVVLASASPRRREILDLAGVVFDVIPSHFSEvpppEHLLRPQDLVIANAKGKALDVgmrlSQADPETQHLIIGADTIVA 92
Cdd:PRK14363   1 MRIILASSSPRRRQLMELLGIEFEVEKPDVEE----EFLESPEETVRELSLRKAEWV----FKKRKEEEILVIGSDTVVV 72

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 318104865  93 MEGQIMGKPCDREDALRMLTRLNGREHSVITGVAIIltgGAGTRDaevvvVFHEETLVTFSKLSDELVQEHVEGGEPWDK 172
Cdd:PRK14363  73 LDGNILGKPESLEEAKGMLKKLSGRWHVVYTGVAFV---SSETKD-----VIVSSTKVRFRELPESVIDYYVEKYRPLDK 144

                        170       180       190
                 ....*....|....*....|....*....|
gi 318104865 173 AGGYGLQARgGAIMAEAVRGDPLNAAGLPL 202
Cdd:PRK14363 145 AGAYGIQDF-AAVFVEKIEGDFFTVVGFPL 173
PRK14361 PRK14361
Maf-like protein; Provisional
 15-211 2.31e-30

Maf-like protein; Provisional


Pssm-ID: 172837  Cd Length: 187  Bit Score: 110.79  E-value: 2.31e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 318104865  15 VVLASASPRRREILDLAGVVFDVIPSHFSEVPPPEHLLRPQdLVIANAKGKALdvgmrlSQADPETqhLIIGADTIVAME 94
Cdd:PRK14361   1 VILASGSPRRRELLENLGVPFQVVVSGEAEDSTETDPARLA-AELALLKARAV------ARLHPDA--VVIAADTVVALG 71

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 318104865  95 GQIMGKPCDREDALRMLTRLNGREHSVITGVAIIltgGAGTRDAEVvvvfhEETLVTFSKLSDELVQEHVEGGEPWDKAG 174
Cdd:PRK14361  72 GVLLAKPADEAENEAFLRVLSGRTHQVYTGVAVL---SRGTEQVGV-----ERTDVTFRALTAAEISFYARSGEGLDKAG 143

                        170       180       190
                 ....*....|....*....|....*....|....*..
gi 318104865 175 GYGLQARGGAIMAEaVRGDPLNAAGLPLNRLCRELGR 211
Cdd:PRK14361 144 GYGIQGVGMALVSR-VEGDYSNVVGFPLSLVIRLLRG 179
Maf_Ham1 cd00985
Maf_Ham1. Maf, a nucleotide binding protein, has been implicated in inhibition of septum ...
 15-153 7.15e-30

Maf_Ham1. Maf, a nucleotide binding protein, has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea. A Ham1-related protein from Methanococcus jannaschii is a novel NTPase that has been shown to hydrolyze nonstandard nucleotides, such as hypoxanthine/xanthine NTP, but not standard nucleotides.


Pssm-ID: 238485  Cd Length: 131  Bit Score: 107.59  E-value: 7.15e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 318104865  15 VVLASASPRRREILDLAGVV-FDVIPSHFSEVPPPEHllrPQDLVIANAKGKALDVGMRLSQAdpetqhLIIGADTIVAM 93
Cdd:cd00985    1 LILASGSPRRLEELKQIGGIeFEVLPSDIDETGLKGE---PEDTVEELALLKARAVAERLPDA------PVIADDTGLVV 71

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 318104865  94 EGQIMGKPCDREDALRMLTRLNGREHSVITGVAIILTGGagtrdaeVVVVFHEETLVTFS 153
Cdd:cd00985   72 DGRPGGKPARFAEALEMLRGLSGRTAEFVTAVALVDPDG-------KIITFEGETEGKIA 124
PRK04694 PRK04694
Maf-like protein; Reviewed
 17-202 5.62e-28

Maf-like protein; Reviewed


Pssm-ID: 179873  Cd Length: 190  Bit Score: 104.66  E-value: 5.62e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 318104865  17 LASASPRRREILDLAGVVFDVIPSHFSEVPPPEHLlrPQDLVIANAKGKAlDVGMRLSQADpETQHLIIGADTIVAMEGQ 96
Cdd:PRK04694   4 LASRSPRRRELLQRLDVPFQTLQLDVPEVRAADES--PDHYVQRVALEKA-HAGLALVQAA-DADAIVLGSDTEVVLGER 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 318104865  97 IMGKPCDREDALRMLTRLNGREHSVITGVAIILTGGAGtrdAEVVVVfheeTLVTFSKLSDELVQEHVEGGEPWDKAGGY 176
Cdd:PRK04694  80 VFGKPVDVDDAIAMLRALSGRTHQVLTAVVLVCAQRAP---AQALVV----SEVTFDLLDDAQIAAYAASGEPMGKAGAY 152

                        170       180
                 ....*....|....*....|....*.
gi 318104865 177 GLQARGGAIMAEAVrGDPLNAAGLPL 202
Cdd:PRK04694 153 AIQGRAERFIRHLS-GSYSGVMGLPL 177
PRK14367 PRK14367
Maf-like protein; Provisional
 17-212 1.23e-22

Maf-like protein; Provisional


Pssm-ID: 237692  Cd Length: 202  Bit Score: 91.28  E-value: 1.23e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 318104865  17 LASASPRRREILDLAGVVFDVIPSHFSEVPPPEHLLRPQDLVIANAKGK-ALDVGMRLSQADPETQhlIIGADTIVAMEG 95
Cdd:PRK14367   6 LGSNSPRRMEILTQLGYRVVKLPAGIDETVKAGETPARYVQRMAEEKNRtALTLFCETNGTMPDFP--LITADTCVVSDG 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 318104865  96 QIMGKPCDREDALRMLTRLNGREHSVITGVAIILTGGAGTRdaevvvvfHEETLVTFSKLSDELVQEHVEGGEPWDKAGG 175
Cdd:PRK14367  84 IILGKPRSQAEAIEFLNRLSGKQHTVLTAVCIHYRGKTSSR--------VQTNRVVFKPLSSEEISAYVQSGEPMDKAGA 155

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
gi 318104865 176 YGLQARGGaIMAEAVRGDPLNAAGLPLNR---LCRELGRR 212
Cdd:PRK14367 156 YAVQGIGG-IFIQSIEGSFSGIMGLPVYEtvsMLQDLGYR 194
PRK14364 PRK14364
Maf-like protein; Provisional
 17-211 3.12e-20

Maf-like protein; Provisional


Pssm-ID: 184648  Cd Length: 181  Bit Score: 84.28  E-value: 3.12e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 318104865  17 LASASPRRREILDLAGVVFDVIPshfsevPPPEHLLRPQDLVIANAKGKALDVGMRLSQADPETqhLIIGADTIVAMEGQ 96
Cdd:PRK14364   1 LASSSPRRRELLQQLGLNFEIYS------PDIDESVHEGELVHQYVERLAREKAQAVLNIFPDS--VIIAADTSLGLDGQ 72

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 318104865  97 IMGKPCDREDALRMLTRLNGREHSVITGVAIiltggAGTRDAEVVVVfheETLVTFSKLSDELVQEHVEGGEPWDKAGGY 176
Cdd:PRK14364  73 IIGKPDSKQHAFDIWKQLSGRWHDVFSGICI-----ATQQQILSQVV---QTQVEFASLTTQDMEDYWATGEPVGKAGAY 144

                        170       180       190
                 ....*....|....*....|....*....|....*
gi 318104865 177 GLQARGGAIMAEaVRGDPLNAAGLPLNRLCRELGR 211
Cdd:PRK14364 145 AIQGIASQYIPK-IQGSYSNVVGLPLYEFSQLFKR 178
PRK01441 PRK01441
Maf-like protein; Reviewed
 16-202 5.34e-20

Maf-like protein; Reviewed


Pssm-ID: 167232  Cd Length: 207  Bit Score: 84.38  E-value: 5.34e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 318104865  16 VLASASPRRREILDLAGVVFDVI-PSHFSEVPPPEHLLRPQDLVIANAKGKAldvGMRLSQADPETQ-HLIIGADTIVAM 93
Cdd:PRK01441   8 VLASGSPRRVELLNQAGIEPDRLmPADIDETPKRAEHPRSLARRLSREKAEA---ALEALQGDDDWRgAYILAADTVVAV 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 318104865  94 EGQIMGKPCDREDALRMLTRLNGREHSVITGVAIILTGGAgTRDAEVvvvfheETLVTFSKLSDELVQEHVEGGEPWDKA 173
Cdd:PRK01441  85 GRRILPKAELVDEASQCLRLLSGRNHRVYTGVCLVTPDGK-LRQKLV------ETRVRFKRLSREDIEAYLASGEWRGKA 157

                        170       180
                 ....*....|....*....|....*....
gi 318104865 174 GGYGLQARGGAIMAEAVrGDPLNAAGLPL 202
Cdd:PRK01441 158 GGYAIQGIAGSFVVKLV-GSYTNVVGLPL 185
PRK02141 PRK02141
Maf-like protein; Reviewed
 16-215 8.66e-19

Maf-like protein; Reviewed


Pssm-ID: 235009  Cd Length: 207  Bit Score: 80.95  E-value: 8.66e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 318104865  16 VLASASPRRREILDLAGVVFDVIPSHFSEVPPPEHllRPQDLVIANAKGKALDVGMRLSqADPETqhLIIGADTIVAMEG 95
Cdd:PRK02141  12 ILASSSRYRRELLERLRLPFDVVSPDIDETPLAGE--TPAATALRLAAAKARAVAATID-APPGA--LVIGSDQVATFDG 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 318104865  96 QIMGKPCDREDALRMLTRLNGRE---HSVITgvaiILTGGAGTRDAEVVVvfheeTLVTFSKLSDELVQEHVEGGEPWDK 172
Cdd:PRK02141  87 LQIGKPGTHERALAQLQAMRGRTvefHSALC----LYDSRTGETQSEDVV-----TRVRFRTLTDAELDAYLRAETPYDV 157

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....
gi 318104865 173 AGGYGLQARGGAIMaEAVRG-DPLNAAGLPLNRLCRELGRRLLP 215
Cdd:PRK02141 158 AGSAKSEGLGIALL-DAIDSdDPTALVGLPLIALTRMLRAAGYP 200
PRK14366 PRK14366
Maf-like protein; Provisional
 15-202 1.27e-18

Maf-like protein; Provisional


Pssm-ID: 237691  Cd Length: 195  Bit Score: 80.23  E-value: 1.27e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 318104865  15 VVLASASPRRREILDLAGVV-FDVIPSHFSEVPPPEHLlrPQDLVIANAKGKALDVgmRLSQADpetqHLIIGADTIVAM 93
Cdd:PRK14366   7 LILASSSKQRLALLEQIGVVpGEIVSPDIDESPLKKEL--PKDYSIRMAKEKAEKV--QSLRPD----KFVLGADTVVCC 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 318104865  94 EGQIMGKPCDREDALRMLTRLNGREHSVITGVAiILTGGAGTRDAEVVvvfheeTLVTFSKLSDELVQEHVEGGEPWDKA 173
Cdd:PRK14366  79 GRRILLKAETEEQAEEYLELLSGRRHRVYTSVC-LYTPGGKLHIRSVV------TVVKFKRLSKQEIKYYIASGEWKGKA 151

                        170       180
                 ....*....|....*....|....*....
gi 318104865 174 GGYGLQARGGAIMAeAVRGDPLNAAGLPL 202
Cdd:PRK14366 152 GGCNIQGLAGKFVL-SINGSYSSIIGLPL 179
PRK02478 PRK02478
Maf-like protein; Reviewed
 15-209 3.02e-14

Maf-like protein; Reviewed


Pssm-ID: 167380  Cd Length: 199  Bit Score: 68.61  E-value: 3.02e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 318104865  15 VVLASASPRRREILDLAGVVFDVIPSHFSE----VPPPEHLLRPQDLVIANAKGKALDVGMRLSQAdpetqhLIIGADTI 90
Cdd:PRK02478   5 LILASKSPFRRALLENAGLEFSAAAADIDEraveAPLEESGATPEDVALVLAEAKAIDVSERFPGA------LVIGCDQT 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 318104865  91 VAMEGQIMGKPCDREDALRMLTRLNGREHSVITGVAIIltggagtRDAEVV--VVFHEEtlVTFSKLSDELVQEHVE--G 166
Cdd:PRK02478  79 MSLGDEVFHKPKDMEEARRHLQKLSGKTHQLNSAVVLV-------RDGKVLwrHVSIAH--MTMRDLDAGFIGRHLArvG 149

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|...
gi 318104865 167 GEPWDKAGGYGLQARGGAIMaEAVRGDPLNAAGLPLNRLCREL 209
Cdd:PRK02478 150 EKALSSVGAYQLEGEGIQLF-EKIEGDYFTILGLPLLPLLAKL 191
PRK04056 PRK04056
septum formation inhibitor Maf;
15-188 5.72e-14

septum formation inhibitor Maf;


Pssm-ID: 179732  Cd Length: 180  Bit Score: 67.30  E-value: 5.72e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 318104865  15 VVLASASPRRREILDLAGVVFDVIPSHFSEvpppEHLL--RPQDLVIANAKGKALDVGMRLSQADPetqhlIIGADTIVA 92
Cdd:PRK04056   2 IILASSSSTRANLLKEAGIEFEQKSLDFDE----ESIKktSPKEFVYLAVKGKLEQFLKKYGNECN-----LLVADSVVS 72

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 318104865  93 MEGQIMGKPCDREDALRMLTRLNGREHSVITgvAIILTGgagtRDAEVVVVfhEETLVTFSKLSDELVQEHVEGGEpWdk 172
Cdd:PRK04056  73 CGNKILRKAKDKEEAREMLKLQSGNEISVLT--CMILKS----PEKEWLDL--SVTTYRFKKFDEDDLEKYLESGL-W-- 141

                        170
                 ....*....|....*.
gi 318104865 173 aggyglQARGGAIMAE 188
Cdd:PRK04056 142 ------QGKAGACMVE 151
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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