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Conserved domains on  [gi|294345478|ref|NP_001100941|]
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CCR4-NOT transcription complex subunit 3 [Rattus norvegicus]

Protein Classification

CNOT2/3/5 family protein( domain architecture ID 10513407)

CNOT2/3/5 family protein is a component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation

Gene Ontology:  GO:0006355|GO:0030014
PubMed:  38009591|32299921|33138308|22027279|28271483

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Not3 pfam04065
Not1 N-terminal domain, CCR4-Not complex component;
3-229 9.67e-131

Not1 N-terminal domain, CCR4-Not complex component;


:

Pssm-ID: 461155 [Multi-domain]  Cd Length: 228  Bit Score: 386.90  E-value: 9.67e-131
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294345478    3 DKRKLQGEIDRCLKKVSEGVEQFEDIWQKLHNAANANQKEKYEADLKKEIKKLQRLRDQIKTWVASNEIKDKRQLIENRK 82
Cdd:pfam04065   1 AARKLQQEIDRTLKKVAEGLEEFDDIYEKLESATNSSQKEKLEADLKKEIKKLQRLRDQIKTWLSSNDIKDKKKLLENRK 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294345478   83 LIETQMERFKVVERETKTKAYSKEGLGLAQ--KVDPAQKEKEEVGQWLTNTIDTLNMQVDQFESEVESLSVQTRkKKGDK 160
Cdd:pfam04065  81 LIEEAMERFKAVEKESKTKAFSKEGLSLAAasKLDPKEKEKAEARDWLSDSIDELNRQIEALEAEIESLQAQKK-KKKKD 159

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 294345478  161 DKQDRIEGLKRHIEKHRYHVRMLETILRMLDNDSILVDAIRKIKDDVEYYVDSSQDPDFEENEFLYDDL 229
Cdd:pfam04065 160 SEKARLEELEKLIERHKFHIEKLELILRLLENGELDPEQVDDIKEDIEYYVESNQDPDFVEDEDIYDDL 228
NOT2_3_5 pfam04153
NOT2 / NOT3 / NOT5 family; NOT1, NOT2, NOT3, NOT4 and NOT5 form a nuclear complex that ...
 618-743 8.85e-57

NOT2 / NOT3 / NOT5 family; NOT1, NOT2, NOT3, NOT4 and NOT5 form a nuclear complex that negatively regulates the basal and activated transcription of many genes. This family includes NOT2, NOT3 and NOT5.


:

Pssm-ID: 461199  Cd Length: 121  Bit Score: 189.35  E-value: 8.85e-57
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294345478  618 AAWHHMPHPSDSERIRQYLPRNPCPTPpyhhQMPPPHSDTVEFYQRLSTETLFFIFYYLEGTKAQYLAAKALKKQSWRFH 697
Cdd:pfam04153   1 YSTFNSPWPLDAERPYEPDFRNPACYP----QEPLPRLESPEKFSKFDDETLFYIFYSMPGDYAQYLAAKELKKRSWRYH 76

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*.
gi 294345478  698 TKYMMWFQRHEEPKTITDEFEQGTYIYFDYeKWGQRKKEGFTFEYR 743
Cdd:pfam04153  77 KKLRTWFTRDEEPKVITNEYERGTYIYFDY-TWEQRRKKDFTLDYE 121
PHA03247 super family cl33720
large tegument protein UL36; Provisional
 288-657 9.51e-06

large tegument protein UL36; Provisional


The actual alignment was detected with superfamily member PHA03247:

Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 49.55  E-value: 9.51e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294345478  288 RGRSTDSEVSQSPAKNGSKPVHSNQHPQSPAVPPTYPSGPPPATSALSSTPGNNGASTPAAPPSALGPKASPAPSHNS-- 365
Cdd:PHA03247 2585 RARRPDAPPQSARPRAPVDDRGDPRGPAPPSPLPPDTHAPDPPPPSPSPAANEPDPHPPPTVPPPERPRDDPAPGRVSrp 2664

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294345478  366 ---GTPAPYAQAVAPPNASGPSNAQP---------RPPsAQPSGGSGGGSGGSSSNSNSGTGGGAGKQNGATSYSSVVAD 433
Cdd:PHA03247 2665 rraRRLGRAAQASSPPQRPRRRAARPtvgsltslaDPP-PPPPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPA 2743

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294345478  434 SPAEVALSSSGGSSASSQAlgpTSGPHNPAPSTLKESST--AAPSGAGSVASGSGNNSGGPSLLVPLPVNPPSSPTPSFS 511
Cdd:PHA03247 2744 VPAGPATPGGPARPARPPT---TAGPPAPAPPAAPAAGPprRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPP 2820

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294345478  512 EAKAAGTlLNGPPQFSTTPEIKAPEPLSSLKSM----------AERAAISSGIEDPVPTLHLTDRDIilsstsapptsSQ 581
Cdd:PHA03247 2821 AASPAGP-LPPPTSAQPTAPPPPPGPPPPSLPLggsvapggdvRRRPPSRSPAAKPAAPARPPVRRL-----------AR 2888

                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 294345478  582 PPLQLSEVNIPLSlgvcPLGPVSLTKEQLYQQAMEEAAWHHMPhpsdserirqyLPRNPCPTPPYHHQMPPPHSDT 657
Cdd:PHA03247 2889 PAVSRSTESFALP----PDQPERPPQPQAPPPPQPQPQPPPPP-----------QPQPPPPPPPRPQPPLAPTTDP 2949
 
Name Accession Description Interval E-value
Not3 pfam04065
Not1 N-terminal domain, CCR4-Not complex component;
3-229 9.67e-131

Not1 N-terminal domain, CCR4-Not complex component;


Pssm-ID: 461155 [Multi-domain]  Cd Length: 228  Bit Score: 386.90  E-value: 9.67e-131
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294345478    3 DKRKLQGEIDRCLKKVSEGVEQFEDIWQKLHNAANANQKEKYEADLKKEIKKLQRLRDQIKTWVASNEIKDKRQLIENRK 82
Cdd:pfam04065   1 AARKLQQEIDRTLKKVAEGLEEFDDIYEKLESATNSSQKEKLEADLKKEIKKLQRLRDQIKTWLSSNDIKDKKKLLENRK 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294345478   83 LIETQMERFKVVERETKTKAYSKEGLGLAQ--KVDPAQKEKEEVGQWLTNTIDTLNMQVDQFESEVESLSVQTRkKKGDK 160
Cdd:pfam04065  81 LIEEAMERFKAVEKESKTKAFSKEGLSLAAasKLDPKEKEKAEARDWLSDSIDELNRQIEALEAEIESLQAQKK-KKKKD 159

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 294345478  161 DKQDRIEGLKRHIEKHRYHVRMLETILRMLDNDSILVDAIRKIKDDVEYYVDSSQDPDFEENEFLYDDL 229
Cdd:pfam04065 160 SEKARLEELEKLIERHKFHIEKLELILRLLENGELDPEQVDDIKEDIEYYVESNQDPDFVEDEDIYDDL 228
NOT2_3_5 pfam04153
NOT2 / NOT3 / NOT5 family; NOT1, NOT2, NOT3, NOT4 and NOT5 form a nuclear complex that ...
 618-743 8.85e-57

NOT2 / NOT3 / NOT5 family; NOT1, NOT2, NOT3, NOT4 and NOT5 form a nuclear complex that negatively regulates the basal and activated transcription of many genes. This family includes NOT2, NOT3 and NOT5.


Pssm-ID: 461199  Cd Length: 121  Bit Score: 189.35  E-value: 8.85e-57
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294345478  618 AAWHHMPHPSDSERIRQYLPRNPCPTPpyhhQMPPPHSDTVEFYQRLSTETLFFIFYYLEGTKAQYLAAKALKKQSWRFH 697
Cdd:pfam04153   1 YSTFNSPWPLDAERPYEPDFRNPACYP----QEPLPRLESPEKFSKFDDETLFYIFYSMPGDYAQYLAAKELKKRSWRYH 76

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*.
gi 294345478  698 TKYMMWFQRHEEPKTITDEFEQGTYIYFDYeKWGQRKKEGFTFEYR 743
Cdd:pfam04153  77 KKLRTWFTRDEEPKVITNEYERGTYIYFDY-TWEQRRKKDFTLDYE 121
CDC36 COG5601
General negative regulator of transcription subunit [Transcription];
643-746 4.25e-14

General negative regulator of transcription subunit [Transcription];


Pssm-ID: 227888  Cd Length: 172  Bit Score: 70.78  E-value: 4.25e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294345478 643 TPPYHHQMPPPHSDTVEFYQR----LSTETLFFIFYYLEGTKAQYLAAKALKKQSWRFHTKYMMW--FQRHEEPKTITDE 716
Cdd:COG5601   64 LPNCYPNAPNPPIFKVNIEDMkmdnFHDETLFYIFYSFPNDVLQEKAYDELLKRNWRFHKMLKCWltFNPGMSPATADHV 143

                         90       100       110
                 ....*....|....*....|....*....|
gi 294345478 717 FEQGTYIYFDYEKWGQRKKEgFTFEYRYLE 746
Cdd:COG5601  144 KERGSYVFFDPFSWSKVSLD-FLLDYKAVR 172
PHA03247 PHA03247
large tegument protein UL36; Provisional
 288-657 9.51e-06

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 49.55  E-value: 9.51e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294345478  288 RGRSTDSEVSQSPAKNGSKPVHSNQHPQSPAVPPTYPSGPPPATSALSSTPGNNGASTPAAPPSALGPKASPAPSHNS-- 365
Cdd:PHA03247 2585 RARRPDAPPQSARPRAPVDDRGDPRGPAPPSPLPPDTHAPDPPPPSPSPAANEPDPHPPPTVPPPERPRDDPAPGRVSrp 2664

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294345478  366 ---GTPAPYAQAVAPPNASGPSNAQP---------RPPsAQPSGGSGGGSGGSSSNSNSGTGGGAGKQNGATSYSSVVAD 433
Cdd:PHA03247 2665 rraRRLGRAAQASSPPQRPRRRAARPtvgsltslaDPP-PPPPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPA 2743

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294345478  434 SPAEVALSSSGGSSASSQAlgpTSGPHNPAPSTLKESST--AAPSGAGSVASGSGNNSGGPSLLVPLPVNPPSSPTPSFS 511
Cdd:PHA03247 2744 VPAGPATPGGPARPARPPT---TAGPPAPAPPAAPAAGPprRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPP 2820

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294345478  512 EAKAAGTlLNGPPQFSTTPEIKAPEPLSSLKSM----------AERAAISSGIEDPVPTLHLTDRDIilsstsapptsSQ 581
Cdd:PHA03247 2821 AASPAGP-LPPPTSAQPTAPPPPPGPPPPSLPLggsvapggdvRRRPPSRSPAAKPAAPARPPVRRL-----------AR 2888

                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 294345478  582 PPLQLSEVNIPLSlgvcPLGPVSLTKEQLYQQAMEEAAWHHMPhpsdserirqyLPRNPCPTPPYHHQMPPPHSDT 657
Cdd:PHA03247 2889 PAVSRSTESFALP----PDQPERPPQPQAPPPPQPQPQPPPPP-----------QPQPPPPPPPRPQPPLAPTTDP 2949
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
8-216 1.71e-05

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 48.52  E-value: 1.71e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294345478   8 QGEID----------RCLKKVSeGVEQFEDIWQKLhnaananqkekyeADLKKEIK-KLQRLRDQIKtwvASNEIKDkrq 76
Cdd:PRK03918 134 QGEIDailesdesreKVVRQIL-GLDDYENAYKNL-------------GEVIKEIKrRIERLEKFIK---RTENIEE--- 193

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294345478  77 lienrkLIETQMERFKVVERETKTKaySKEGLGLAQKVDPAQKEKEEVGQwLTNTIDTLNMQVDQFESEVESLsvqtrkk 156
Cdd:PRK03918 194 ------LIKEKEKELEEVLREINEI--SSELPELREELEKLEKEVKELEE-LKEEIEELEKELESLEGSKRKL------- 257

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 294345478 157 kgdkdkQDRIEGLKRHIEKHRYHVRMLETILRMLDNDSILVDAIRKIKDDVEYYVDSSQD 216
Cdd:PRK03918 258 ------EEKIRELEERIEELKKEIEELEEKVKELKELKEKAEEYIKLSEFYEEYLDELRE 311
Herpes_BLLF1 pfam05109
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ...
 291-564 6.96e-04

Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.


Pssm-ID: 282904 [Multi-domain]  Cd Length: 886  Bit Score: 42.98  E-value: 6.96e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294345478  291 STDSEVSQSPA--KNGSKPVHSNQHPQSPAVPPTYPSGPPPATSALSSTPgNNGASTPAAP---PSALGPK--------- 356
Cdd:pfam05109 469 STADVTSPTPAgtTSGASPVTPSPSPRDNGTESKAPDMTSPTSAVTTPTP-NATSPTPAVTtptPNATSPTlgktsptsa 547

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294345478  357 -ASPAPSHNSGTPapyAQAVAPPNASGPSNAQPRPPSAqpSGGSGGGSGGSSSNSNSGTGGGAGKQNGATSYSSVVADSP 435
Cdd:pfam05109 548 vTTPTPNATSPTP---AVTTPTPNATIPTLGKTSPTSA--VTTPTPNATSPTVGETSPQANTTNHTLGGTSSTPVVTSPP 622

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294345478  436 AEVALSSS------GGSSASSQALGPTSGPHNPAPSTLKESSTAAPsgagsvASGSGNNSGGPSLLVPLPVNPPSSPTPS 509
Cdd:pfam05109 623 KNATSAVTtgqhniTSSSTSSMSLRPSSISETLSPSTSDNSTSHMP------LLTSAHPTGGENITQVTPASTSTHHVST 696

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 294345478  510 FSEAKAAGTL--LNGPPQFSTTPEikaPEPLSSLKSMAERAAIS----SGIEDPVPTLHLT 564
Cdd:pfam05109 697 SSPAPRPGTTsqASGPGNSSTSTK---PGEVNVTKGTPPKNATSpqapSGQKTAVPTVTST 754
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 3-149 3.39e-03

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 40.77  E-value: 3.39e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294345478    3 DKRKLQGEIDRCLKKVSEGVEQFEDIwqklhnaananqkEKYEADLKKEIKKLQRLRDQIKTWVA--SNEIKD-KRQLIE 79
Cdd:TIGR04523 420 EKELLEKEIERLKETIIKNNSEIKDL-------------TNQDSVKELIIKNLDNTRESLETQLKvlSRSINKiKQNLEQ 486

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294345478   80 NRKLIETQMERFKVVERETKTkayskeglgLAQKVDPAQKEKEEvgqwLTNTIDTLNMQVDQFESEVESL 149
Cdd:TIGR04523 487 KQKELKSKEKELKKLNEEKKE---------LEEKVKDLTKKISS----LKEKIEKLESEKKEKESKISDL 543
 
Name Accession Description Interval E-value
Not3 pfam04065
Not1 N-terminal domain, CCR4-Not complex component;
3-229 9.67e-131

Not1 N-terminal domain, CCR4-Not complex component;


Pssm-ID: 461155 [Multi-domain]  Cd Length: 228  Bit Score: 386.90  E-value: 9.67e-131
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294345478    3 DKRKLQGEIDRCLKKVSEGVEQFEDIWQKLHNAANANQKEKYEADLKKEIKKLQRLRDQIKTWVASNEIKDKRQLIENRK 82
Cdd:pfam04065   1 AARKLQQEIDRTLKKVAEGLEEFDDIYEKLESATNSSQKEKLEADLKKEIKKLQRLRDQIKTWLSSNDIKDKKKLLENRK 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294345478   83 LIETQMERFKVVERETKTKAYSKEGLGLAQ--KVDPAQKEKEEVGQWLTNTIDTLNMQVDQFESEVESLSVQTRkKKGDK 160
Cdd:pfam04065  81 LIEEAMERFKAVEKESKTKAFSKEGLSLAAasKLDPKEKEKAEARDWLSDSIDELNRQIEALEAEIESLQAQKK-KKKKD 159

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 294345478  161 DKQDRIEGLKRHIEKHRYHVRMLETILRMLDNDSILVDAIRKIKDDVEYYVDSSQDPDFEENEFLYDDL 229
Cdd:pfam04065 160 SEKARLEELEKLIERHKFHIEKLELILRLLENGELDPEQVDDIKEDIEYYVESNQDPDFVEDEDIYDDL 228
NOT2_3_5 pfam04153
NOT2 / NOT3 / NOT5 family; NOT1, NOT2, NOT3, NOT4 and NOT5 form a nuclear complex that ...
 618-743 8.85e-57

NOT2 / NOT3 / NOT5 family; NOT1, NOT2, NOT3, NOT4 and NOT5 form a nuclear complex that negatively regulates the basal and activated transcription of many genes. This family includes NOT2, NOT3 and NOT5.


Pssm-ID: 461199  Cd Length: 121  Bit Score: 189.35  E-value: 8.85e-57
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294345478  618 AAWHHMPHPSDSERIRQYLPRNPCPTPpyhhQMPPPHSDTVEFYQRLSTETLFFIFYYLEGTKAQYLAAKALKKQSWRFH 697
Cdd:pfam04153   1 YSTFNSPWPLDAERPYEPDFRNPACYP----QEPLPRLESPEKFSKFDDETLFYIFYSMPGDYAQYLAAKELKKRSWRYH 76

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*.
gi 294345478  698 TKYMMWFQRHEEPKTITDEFEQGTYIYFDYeKWGQRKKEGFTFEYR 743
Cdd:pfam04153  77 KKLRTWFTRDEEPKVITNEYERGTYIYFDY-TWEQRRKKDFTLDYE 121
CDC36 COG5601
General negative regulator of transcription subunit [Transcription];
643-746 4.25e-14

General negative regulator of transcription subunit [Transcription];


Pssm-ID: 227888  Cd Length: 172  Bit Score: 70.78  E-value: 4.25e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294345478 643 TPPYHHQMPPPHSDTVEFYQR----LSTETLFFIFYYLEGTKAQYLAAKALKKQSWRFHTKYMMW--FQRHEEPKTITDE 716
Cdd:COG5601   64 LPNCYPNAPNPPIFKVNIEDMkmdnFHDETLFYIFYSFPNDVLQEKAYDELLKRNWRFHKMLKCWltFNPGMSPATADHV 143

                         90       100       110
                 ....*....|....*....|....*....|
gi 294345478 717 FEQGTYIYFDYEKWGQRKKEgFTFEYRYLE 746
Cdd:COG5601  144 KERGSYVFFDPFSWSKVSLD-FLLDYKAVR 172
PHA03247 PHA03247
large tegument protein UL36; Provisional
 288-657 9.51e-06

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 49.55  E-value: 9.51e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294345478  288 RGRSTDSEVSQSPAKNGSKPVHSNQHPQSPAVPPTYPSGPPPATSALSSTPGNNGASTPAAPPSALGPKASPAPSHNS-- 365
Cdd:PHA03247 2585 RARRPDAPPQSARPRAPVDDRGDPRGPAPPSPLPPDTHAPDPPPPSPSPAANEPDPHPPPTVPPPERPRDDPAPGRVSrp 2664

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294345478  366 ---GTPAPYAQAVAPPNASGPSNAQP---------RPPsAQPSGGSGGGSGGSSSNSNSGTGGGAGKQNGATSYSSVVAD 433
Cdd:PHA03247 2665 rraRRLGRAAQASSPPQRPRRRAARPtvgsltslaDPP-PPPPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPA 2743

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294345478  434 SPAEVALSSSGGSSASSQAlgpTSGPHNPAPSTLKESST--AAPSGAGSVASGSGNNSGGPSLLVPLPVNPPSSPTPSFS 511
Cdd:PHA03247 2744 VPAGPATPGGPARPARPPT---TAGPPAPAPPAAPAAGPprRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPP 2820

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294345478  512 EAKAAGTlLNGPPQFSTTPEIKAPEPLSSLKSM----------AERAAISSGIEDPVPTLHLTDRDIilsstsapptsSQ 581
Cdd:PHA03247 2821 AASPAGP-LPPPTSAQPTAPPPPPGPPPPSLPLggsvapggdvRRRPPSRSPAAKPAAPARPPVRRL-----------AR 2888

                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 294345478  582 PPLQLSEVNIPLSlgvcPLGPVSLTKEQLYQQAMEEAAWHHMPhpsdserirqyLPRNPCPTPPYHHQMPPPHSDT 657
Cdd:PHA03247 2889 PAVSRSTESFALP----PDQPERPPQPQAPPPPQPQPQPPPPP-----------QPQPPPPPPPRPQPPLAPTTDP 2949
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
8-216 1.71e-05

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 48.52  E-value: 1.71e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294345478   8 QGEID----------RCLKKVSeGVEQFEDIWQKLhnaananqkekyeADLKKEIK-KLQRLRDQIKtwvASNEIKDkrq 76
Cdd:PRK03918 134 QGEIDailesdesreKVVRQIL-GLDDYENAYKNL-------------GEVIKEIKrRIERLEKFIK---RTENIEE--- 193

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294345478  77 lienrkLIETQMERFKVVERETKTKaySKEGLGLAQKVDPAQKEKEEVGQwLTNTIDTLNMQVDQFESEVESLsvqtrkk 156
Cdd:PRK03918 194 ------LIKEKEKELEEVLREINEI--SSELPELREELEKLEKEVKELEE-LKEEIEELEKELESLEGSKRKL------- 257

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 294345478 157 kgdkdkQDRIEGLKRHIEKHRYHVRMLETILRMLDNDSILVDAIRKIKDDVEYYVDSSQD 216
Cdd:PRK03918 258 ------EEKIRELEERIEELKKEIEELEEKVKELKELKEKAEEYIKLSEFYEEYLDELRE 311
PRK07003 PRK07003
DNA polymerase III subunit gamma/tau;
334-489 8.18e-05

DNA polymerase III subunit gamma/tau;


Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 46.00  E-value: 8.18e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294345478 334 LSSTPGNNGASTPAAPPSALGPKASPAPSHNSGTPAPYAQAVAPPNASGPSNAQPRPPSAQPsGGSGGGSGGSSSNSNSG 413
Cdd:PRK07003 356 LAFEPAVTGGGAPGGGVPARVAGAVPAPGARAAAAVGASAVPAVTAVTGAAGAALAPKAAAA-AAATRAEAPPAAPAPPA 434

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 294345478 414 TGGGAGKQNGATSYSSVVADSPAEVALSSSGGSSASSQALGPTSGPHNPA-PSTLKESSTAAPSGAGSVASGSGNNS 489
Cdd:PRK07003 435 TADRGDDAADGDAPVPAKANARASADSRCDERDAQPPADSGSASAPASDApPDAAFEPAPRAAAPSAATPAAVPDAR 511
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 212-493 1.18e-04

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 45.93  E-value: 1.18e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294345478  212 DSSQDPDFEEN-EFLYDDLDLEDIPQALVATS----------PPSHSHMEDEIFNQSSSTPTSTTSSSPIPPSPANCTTE 280
Cdd:PHA03307   30 DAADDLLSGSQgQLVSDSAELAAVTVVAGAAAcdrfepptgpPPGPGTEAPANESRSTPTWSLSTLAPASPAREGSPTPP 109

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294345478  281 NSEDDKKRGRSTDSE--------VSQSPAKNGSKPVHSNQHPQSPAVPPTYPSGPPPATSALSSTPGNNGASTPAAPPSa 352
Cdd:PHA03307  110 GPSSPDPPPPTPPPAspppspapDLSEMLRPVGSPGPPPAASPPAAGASPAAVASDAASSRQAALPLSSPEETARAPSS- 188

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294345478  353 lgPKASPAPSHNSGTPAPYAQAVAPPNASGPSNAQPRPPSAQPSGGSGGGSGGSSSNSNSGTGGGAGKQNGATSYSSVVA 432
Cdd:PHA03307  189 --PPAEPPPSTPPAAASPRPPRRSSPISASASSPAPAPGRSAADDAGASSSDSSSSESSGCGWGPENECPLPRPAPITLP 266

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 294345478  433 DSPAEVALSSSGGSSASSQALGPTSGPHNPAPSTLKESSTAAPSGAGSVASGSGNNSGGPS 493
Cdd:PHA03307  267 TRIWEASGWNGPSSRPGPASSSSSPRERSPSPSPSSPGSGPAPSSPRASSSSSSSRESSSS 327
PHA03247 PHA03247
large tegument protein UL36; Provisional
 307-666 1.47e-04

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 45.70  E-value: 1.47e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294345478  307 PVHSNQHPQSPavpPTYPSGPPPATSALSSTPGNNGASTPAAPPSALGPkASPAPSHNSGTPAPYAQAVAPPNASGPsnA 386
Cdd:PHA03247 2694 SLTSLADPPPP---PPTPEPAPHALVSATPLPPGPAAARQASPALPAAP-APPAVPAGPATPGGPARPARPPTTAGP--P 2767

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294345478  387 QPRPPSAQPSGGSGGGSGGSSSNSNSGTGGGAGKQNGATSYSSVVADSPAEVALSSSGGSSASSQALGPTSGPHNPAPst 466
Cdd:PHA03247 2768 APAPPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGP-- 2845

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294345478  467 lkeSSTAAPSGaGSVASGSGNNSGGPSLLVPLPVNPPSSPTpsfseakaAGTLLNGPPQFSTTPEIKAPEPLsslksmaE 546
Cdd:PHA03247 2846 ---PPPSLPLG-GSVAPGGDVRRRPPSRSPAAKPAAPARPP--------VRRLARPAVSRSTESFALPPDQP-------E 2906

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294345478  547 RAAISSGIEDPVPTlhltdrdiilsSTSAPPTSSQPPLQlsevniPLSLGVCPLGPVSLTKEQLYQQAMEEAAWHHMPHP 626
Cdd:PHA03247 2907 RPPQPQAPPPPQPQ-----------PQPPPPPQPQPPPP------PPPRPQPPLAPTTDPAGAGEPSGAVPQPWLGALVP 2969

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|
gi 294345478  627 SDSERIRQylpRNPCPTPPYHHQMPPPHSDTVEFYQRLST 666
Cdd:PHA03247 2970 GRVAVPRF---RVPQPAPSREAPASSTPPLTGHSLSRVSS 3006
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 342-486 3.07e-04

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 44.21  E-value: 3.07e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294345478 342 GASTPAAPPSALGPKASPAPSHNSGTPAPYAQAVAPPNASGPSNAQPRPPSAQPSGGSGGGSGGSSsnsnsgtgggagkq 421
Cdd:PRK07764 389 GGAGAPAAAAPSAAAAAPAAAPAPAAAAPAAAAAPAPAAAPQPAPAPAPAPAPPSPAGNAPAGGAP-------------- 454

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 294345478 422 ngatsySSVVADSPAEVAlsssggsSASSQALGPTSGPHNPAPSTLKESSTAAPSGAGSVASGSG 486
Cdd:PRK07764 455 ------SPPPAAAPSAQP-------APAPAAAPEPTAAPAPAPPAAPAPAAAPAAPAAPAAPAGA 506
Herpes_BLLF1 pfam05109
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ...
 291-564 6.96e-04

Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.


Pssm-ID: 282904 [Multi-domain]  Cd Length: 886  Bit Score: 42.98  E-value: 6.96e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294345478  291 STDSEVSQSPA--KNGSKPVHSNQHPQSPAVPPTYPSGPPPATSALSSTPgNNGASTPAAP---PSALGPK--------- 356
Cdd:pfam05109 469 STADVTSPTPAgtTSGASPVTPSPSPRDNGTESKAPDMTSPTSAVTTPTP-NATSPTPAVTtptPNATSPTlgktsptsa 547

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294345478  357 -ASPAPSHNSGTPapyAQAVAPPNASGPSNAQPRPPSAqpSGGSGGGSGGSSSNSNSGTGGGAGKQNGATSYSSVVADSP 435
Cdd:pfam05109 548 vTTPTPNATSPTP---AVTTPTPNATIPTLGKTSPTSA--VTTPTPNATSPTVGETSPQANTTNHTLGGTSSTPVVTSPP 622

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294345478  436 AEVALSSS------GGSSASSQALGPTSGPHNPAPSTLKESSTAAPsgagsvASGSGNNSGGPSLLVPLPVNPPSSPTPS 509
Cdd:pfam05109 623 KNATSAVTtgqhniTSSSTSSMSLRPSSISETLSPSTSDNSTSHMP------LLTSAHPTGGENITQVTPASTSTHHVST 696

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 294345478  510 FSEAKAAGTL--LNGPPQFSTTPEikaPEPLSSLKSMAERAAIS----SGIEDPVPTLHLT 564
Cdd:pfam05109 697 SSPAPRPGTTsqASGPGNSSTSTK---PGEVNVTKGTPPKNATSpqapSGQKTAVPTVTST 754
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 338-556 8.05e-04

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 43.05  E-value: 8.05e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294345478 338 PGNNGASTPAAPPSALGPKASPAPSHNSGTPAPyAQAVAPPNASGPSNAQPRPPSAQPSGGSGGGSGGSSSNSNSGTGGG 417
Cdd:PRK07764 592 PGAAGGEGPPAPASSGPPEEAARPAAPAAPAAP-AAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDGGDGWP 670

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294345478 418 AGKQNGATSYSSVVADSPAEVAlsssggssasSQALGPTSGPHNPAPSTLKESSTAAPSGAGSVASGSGNNSGGPSLLVP 497
Cdd:PRK07764 671 AKAGGAAPAAPPPAPAPAAPAA----------PAGAAPAQPAPAPAATPPAGQADDPAAQPPQAAQGASAPSPAADDPVP 740

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 294345478 498 LPVNPPSSPTPSFSEAKAAGTLLNGPPQFSTTPeiKAPEPLSSLKSMAERAAISSGIED 556
Cdd:PRK07764 741 LPPEPDDPPDPAGAPAQPPPPPAPAPAAAPAAA--PPPSPPSEEEEMAEDDAPSMDDED 797
PHA03247 PHA03247
large tegument protein UL36; Provisional
 314-653 9.52e-04

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 43.00  E-value: 9.52e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294345478  314 PQSPAVpPTYPSGPPPATSALSSTPGNNGASTPAAPPSALGPKASP-APSHNSGTPApyaqAVAPPNASGPSNAQPRPPS 392
Cdd:PHA03247 2554 PLPPAA-PPAAPDRSVPPPRPAPRPSEPAVTSRARRPDAPPQSARPrAPVDDRGDPR----GPAPPSPLPPDTHAPDPPP 2628

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294345478  393 AQPSGGSGGGSGGSSSNSNSGTGGGAGKQNGATSYSSvVADSPAEVALSSSGGSSASSQALGPTSG-------PHNPAPS 465
Cdd:PHA03247 2629 PSPSPAANEPDPHPPPTVPPPERPRDDPAPGRVSRPR-RARRLGRAAQASSPPQRPRRRAARPTVGsltsladPPPPPPT 2707

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294345478  466 TLKESSTAAPSGAGSVASGSGNNSGGPSLLVPLPVNPPSSPTPSFSEAKAAGTLLNGPPQFSTTPEIKAPEP-------- 537
Cdd:PHA03247 2708 PEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPARPPTTAGPPAPAPPAAPAAGPprrltrpa 2787

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294345478  538 -------LSSLKSMAERAAISSGIEDPVPTLHLTDRDIILSSTSAPPTSSQPPLQLSEVNIPLSLG--VCPLGPVSltKE 608
Cdd:PHA03247 2788 vaslsesRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLGgsVAPGGDVR--RR 2865

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....*..
gi 294345478  609 QLYQQAMEEAAwhHMPHPSDSERIRQYLPRN--PCPTPPYHHQMPPP 653
Cdd:PHA03247 2866 PPSRSPAAKPA--APARPPVRRLARPAVSRSteSFALPPDQPERPPQ 2910
DUF5585 pfam17823
Family of unknown function (DUF5585); This is a family of unknown function found in chordata.
 331-645 1.67e-03

Family of unknown function (DUF5585); This is a family of unknown function found in chordata.


Pssm-ID: 465521 [Multi-domain]  Cd Length: 506  Bit Score: 41.87  E-value: 1.67e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294345478  331 TSALSSTPGNNGASTPAApPSALGPKASPAPShnsgTPAPYAQAVAPPNASGPSNAQPRPPSAQPSGGSGGGSGGSSSNS 410
Cdd:pfam17823 116 AAAASSSPSSAAQSLPAA-IAALPSEAFSAPR----AAACRANASAAPRAAIAAASAPHAASPAPRTAASSTTAASSTTA 190

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294345478  411 NSGTGGGAgkqnGATSYSSVVADSP-AEVALSSSGGSSASSQALGPTSgphNPAPSTLKES-STAAPSGAGSVASGSGNn 488
Cdd:pfam17823 191 ASSAPTTA----ASSAPATLTPARGiSTAATATGHPAAGTALAAVGNS---SPAAGTVTAAvGTVTPAALATLAAAAGT- 262

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294345478  489 sggpsllvplpvnppssptpsfsEAKAAGTLLNGPPQfSTTPeikAPEPLSSLKSMAERAAISSGIEDPVPTLHLT-DRD 567
Cdd:pfam17823 263 -----------------------VASAAGTINMGDPH-ARRL---SPAKHMPSDTMARNPAAPMGAQAQGPIIQVStDQP 315

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 294345478  568 IIlssTSAPPTSSQPPLQLSEVNIPLSLGVCPLGPVSLTKEQLYQQAmeeAAWHHMPHPSDSERIRQYLP-RNPCPTPP 645
Cdd:pfam17823 316 VH---NTAGEPTPSPSNTTLEPNTPKSVASTNLAVVTTTKAQAKEPS---ASPVPVLHTSMIPEVEATSPtTQPSPLLP 388
PRK14971 PRK14971
DNA polymerase III subunit gamma/tau;
295-393 1.99e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237874 [Multi-domain]  Cd Length: 614  Bit Score: 41.68  E-value: 1.99e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294345478 295 EVSQSPAKNGSKPvhSNQHPQSP---AVPPTYPSGPPPATSALSSTPGNNG-ASTPAAPPSALGPKASPAP-SHNSGTPA 369
Cdd:PRK14971 358 QLAQLTQKGDDAS--GGRGPKQHikpVFTQPAAAPQPSAAAAASPSPSQSSaAAQPSAPQSATQPAGTPPTvSVDPPAAV 435

                         90       100
                 ....*....|....*....|....
gi 294345478 370 PYAQAVAPPNASGPSNAQPRPPSA 393
Cdd:PRK14971 436 PVNPPSTAPQAVRPAQFKEEKKIP 459
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 299-480 2.18e-03

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 41.51  E-value: 2.18e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294345478 299 SPAKNGSKPVHSNQHPQSPAVPPTYPSGPPPATSALSSTPGNNGASTPAAPPSALGPKASPAPS-------HNSGTPAPY 371
Cdd:PRK07764 600 PPAPASSGPPEEAARPAAPAAPAAPAAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASdggdgwpAKAGGAAPA 679

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294345478 372 AQAVAPPNASGPSNAQPRPPSAQPsggsgggSGGSSSNSNSGTGGGAGKQNGATSYSSVVADSPAEVALSSSGGSSAssq 451
Cdd:PRK07764 680 APPPAPAPAAPAAPAGAAPAQPAP-------APAATPPAGQADDPAAQPPQAAQGASAPSPAADDPVPLPPEPDDPP--- 749

                        170       180
                 ....*....|....*....|....*....
gi 294345478 452 ALGPTSGPHNPAPSTLKESSTAAPSGAGS 480
Cdd:PRK07764 750 DPAGAPAQPPPPPAPAPAAAPAAAPPPSP 778
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
339-549 3.02e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 41.01  E-value: 3.02e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294345478 339 GNNGASTPAAPPSALGPKASPAPSHNSGTPAPYAQAVAPPNASGPSNAQPRPPSAQPsggsgggsggsSSNSNSGTGGGA 418
Cdd:PRK12323 367 QSGGGAGPATAAAAPVAQPAPAAAAPAAAAPAPAAPPAAPAAAPAAAAAARAVAAAP-----------ARRSPAPEALAA 435

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294345478 419 GKQNGATSYSSVVADSPAEVAlsssggsSASSQALGPTSGPHNPAPSTLKESSTAAPSGAGSVASGSGN--NSGGPSLLV 496
Cdd:PRK12323 436 ARQASARGPGGAPAPAPAPAA-------APAAAARPAAAGPRPVAAAAAAAPARAAPAAAPAPADDDPPpwEELPPEFAS 508

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 294345478 497 PLPVNPPSSPTPSFSEAKAAGTLLNGPPQFSTTPEIKAPEPLSSLKSMAERAA 549
Cdd:PRK12323 509 PAPAQPDAAPAGWVAESIPDPATADPDDAFETLAPAPAAAPAPRAAAATEPVV 561
PRK06549 PRK06549
acetyl-CoA carboxylase biotin carboxyl carrier protein subunit; Validated
 342-390 3.09e-03

acetyl-CoA carboxylase biotin carboxyl carrier protein subunit; Validated


Pssm-ID: 235826 [Multi-domain]  Cd Length: 130  Bit Score: 38.25  E-value: 3.09e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*....
gi 294345478 342 GASTPAAPPSAlgPKASPAPSHNSGTPAPYAQAVAPPnASGPSNAQPRP 390
Cdd:PRK06549  22 GAPAQAAAPAQ--PASTPVPVPTEASPQVEAQAPQPA-AAAGADAMPSP 67
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 3-149 3.39e-03

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 40.77  E-value: 3.39e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294345478    3 DKRKLQGEIDRCLKKVSEGVEQFEDIwqklhnaananqkEKYEADLKKEIKKLQRLRDQIKTWVA--SNEIKD-KRQLIE 79
Cdd:TIGR04523 420 EKELLEKEIERLKETIIKNNSEIKDL-------------TNQDSVKELIIKNLDNTRESLETQLKvlSRSINKiKQNLEQ 486

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294345478   80 NRKLIETQMERFKVVERETKTkayskeglgLAQKVDPAQKEKEEvgqwLTNTIDTLNMQVDQFESEVESL 149
Cdd:TIGR04523 487 KQKELKSKEKELKKLNEEKKE---------LEEKVKDLTKKISS----LKEKIEKLESEKKEKESKISDL 543
PRK14951 PRK14951
DNA polymerase III subunits gamma and tau; Provisional
 343-465 4.78e-03

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237865 [Multi-domain]  Cd Length: 618  Bit Score: 40.47  E-value: 4.78e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294345478 343 ASTPAAPPSALGPKASPAPSHNSGTPAPYAQAVAPPNASGPSNAQPRPPSAQPsggsgggsggsssNSNSGTGGGAGKQN 422
Cdd:PRK14951 378 KKTPARPEAAAPAAAPVAQAAAAPAPAAAPAAAASAPAAPPAAAPPAPVAAPA-------------AAAPAAAPAAAPAA 444

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|...
gi 294345478 423 GATSYSSVVADSPAEVALSSSGGSSASSQALGPTSGPHNPAPS 465
Cdd:PRK14951 445 VALAPAPPAQAAPETVAIPVRVAPEPAVASAAPAPAAAPAAAR 487
PRK07003 PRK07003
DNA polymerase III subunit gamma/tau;
314-482 6.07e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 40.22  E-value: 6.07e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294345478 314 PQSPAVPPTYPSGPPPATSALSSTPGNNGASTPAAPPSALGPKASPAP--SHNSGTPAPYAQAVAPPNASGPS--NAQPR 389
Cdd:PRK07003 385 ARAAAAVGASAVPAVTAVTGAAGAALAPKAAAAAAATRAEAPPAAPAPpaTADRGDDAADGDAPVPAKANARAsaDSRCD 464

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294345478 390 PPSAQPSGGSGGGSGGSSSNSNSGTGGGAGKQNGATSYSSVVADSPAEVALSSSGGSSASSQALGPTSGPHNPApstlkE 469
Cdd:PRK07003 465 ERDAQPPADSGSASAPASDAPPDAAFEPAPRAAAPSAATPAAVPDARAPAAASREDAPAAAAPPAPEARPPTPA-----A 539

                        170
                 ....*....|...
gi 294345478 470 SSTAAPSGAGSVA 482
Cdd:PRK07003 540 AAPAARAGGAAAA 552
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 3-153 6.26e-03

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 40.00  E-value: 6.26e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294345478    3 DKRKLQGEIDRCLKKVSEGVEQFEDIWQKLHNAANANQKEKYEADLKK-EIKKLQRLRDQIKTWVAS--NEIKDKRQLIE 79
Cdd:TIGR04523 322 KLEEIQNQISQNNKIISQLNEQISQLKKELTNSESENSEKQRELEEKQnEIEKLKKENQSYKQEIKNleSQINDLESKIQ 401

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 294345478   80 NRKLIETQME-RFKVVERETKTKaySKEGLGLAQKVDPAQKEKEEvgqwLTNTIDTLNMQVDQFESEVESLSVQT 153
Cdd:TIGR04523 402 NQEKLNQQKDeQIKKLQQEKELL--EKEIERLKETIIKNNSEIKD----LTNQDSVKELIIKNLDNTRESLETQL 470
PRK10856 PRK10856
cytoskeleton protein RodZ;
294-393 7.00e-03

cytoskeleton protein RodZ;


Pssm-ID: 236776 [Multi-domain]  Cd Length: 331  Bit Score: 39.24  E-value: 7.00e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294345478 294 SEVSQSPAKNGSKPVHSNQHPQSPAVPPtypsgpppATSALSSTPGNNGASTPAAPPSALGPKASPAPSHNSGTPAPYAQ 373
Cdd:PRK10856 150 SSAELSQNSGQSVPLDTSTTTDPATTPA--------PAAPVDTTPTNSQTPAVATAPAPAVDPQQNAVVAPSQANVDTAA 221

                         90       100
                 ....*....|....*....|
gi 294345478 374 AVAPPNASGPSNAQPRPPSA 393
Cdd:PRK10856 222 TPAPAAPATPDGAAPLPTDQ 241
PRK14951 PRK14951
DNA polymerase III subunits gamma and tau; Provisional
 313-395 7.15e-03

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237865 [Multi-domain]  Cd Length: 618  Bit Score: 39.70  E-value: 7.15e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294345478 313 HPQSPAVPPTYPSGPPPATSALSSTPGNNGASTPAAPPSALGPKASPAPSHNSGTPAPYAQAVAPPN-ASGPSNAQPRPP 391
Cdd:PRK14951 392 APVAQAAAAPAPAAAPAAAASAPAAPPAAAPPAPVAAPAAAAPAAAPAAAPAAVALAPAPPAQAAPEtVAIPVRVAPEPA 471


                 ....
gi 294345478 392 SAQP 395
Cdd:PRK14951 472 VASA 475
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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