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Conserved domains on  [gi|157820989|ref|NP_001101047|]
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leucine-rich repeat-containing protein 10B [Rattus norvegicus]

Protein Classification

leucine-rich repeat domain-containing protein( domain architecture ID 11469232)

leucine-rich repeat (LRR) domain-containing protein may participate in protein-protein interactions

Gene Ontology:  GO:0005515
PubMed:  11751054|7583641|14747988
SCOP:  4003523

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
24-218 9.12e-34

Leucine-rich repeat (LRR) protein [Transcription];


:

Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 127.36  E-value: 9.12e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157820989  24 QQLELSGRRLRRLPSAVCALSRLQKLYVSGtglrelpeeieelrelrilaldfNKLERLPDGLCRLPRLTRLYLGGNRLL 103
Cdd:COG4886  116 ESLDLSGNQLTDLPEELANLTNLKELDLSN-----------------------NQLTDLPEPLGNLTNLKSLDLSNNQLT 172

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157820989 104 ALPSDFAQLQSLRCLWIEGNFLRRFPRPLLRLVALQSLQMGDNRLRALPAELPRMTGLRGLWLYGNRFEEFPpALLRMGR 183
Cdd:COG4886  173 DLPEELGNLTNLKELDLSNNQITDLPEPLGNLTNLEELDLSGNQLTDLPEPLANLTNLETLDLSNNQLTDLP-ELGNLTN 251

                        170       180       190
                 ....*....|....*....|....*....|....*
gi 157820989 184 LHILDLDRNRLGGFPDLHPLRALRVFSYDHNPVTG 218
Cdd:COG4886  252 LEELDLSNNQLTDLPPLANLTNLKTLDLSNNQLTD 286
 
Name Accession Description Interval E-value
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
24-218 9.12e-34

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 127.36  E-value: 9.12e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157820989  24 QQLELSGRRLRRLPSAVCALSRLQKLYVSGtglrelpeeieelrelrilaldfNKLERLPDGLCRLPRLTRLYLGGNRLL 103
Cdd:COG4886  116 ESLDLSGNQLTDLPEELANLTNLKELDLSN-----------------------NQLTDLPEPLGNLTNLKSLDLSNNQLT 172

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157820989 104 ALPSDFAQLQSLRCLWIEGNFLRRFPRPLLRLVALQSLQMGDNRLRALPAELPRMTGLRGLWLYGNRFEEFPpALLRMGR 183
Cdd:COG4886  173 DLPEELGNLTNLKELDLSNNQITDLPEPLGNLTNLEELDLSGNQLTDLPEPLANLTNLETLDLSNNQLTDLP-ELGNLTN 251

                        170       180       190
                 ....*....|....*....|....*....|....*
gi 157820989 184 LHILDLDRNRLGGFPDLHPLRALRVFSYDHNPVTG 218
Cdd:COG4886  252 LEELDLSNNQLTDLPPLANLTNLKTLDLSNNQLTD 286
PRK15370 PRK15370
type III secretion system effector E3 ubiquitin transferase SlrP;
77-222 3.58e-08

type III secretion system effector E3 ubiquitin transferase SlrP;


Pssm-ID: 185268 [Multi-domain]  Cd Length: 754  Bit Score: 54.32  E-value: 3.58e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157820989  77 NKLERLPDglcRLP-RLTRLYLGGNRLLALPSDFAQlqSLRCLWIEGNFLRRFPRPLLRlvALQSLQMGDNRLRALPAEL 155
Cdd:PRK15370 230 NQLTSIPA---TLPdTIQEMELSINRITELPERLPS--ALQSLDLFHNKISCLPENLPE--ELRYLSVYDNSIRTLPAHL 302

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 157820989 156 PrmTGLRGLWLYGNRFeEFPPALLRMGrLHILDLDRNRLGGFPDLHPlRALRVFSYDHN-----PVTGPPRV 222
Cdd:PRK15370 303 P--SGITHLNVQSNSL-TALPETLPPG-LKTLEAGENALTSLPASLP-PELQVLDVSKNqitvlPETLPPTI 369
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 77-226 1.53e-05

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 45.16  E-value: 1.53e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157820989  77 NKLERLpDGLCRLPRLTRLYLGGNRLLALpSDFAQLQSLRCLWIEGNFLRR-----F-PRPLLRL-VALQSLQMGDNRLR 149
Cdd:cd21340   56 NQIEKI-ENLENLVNLKKLYLGGNRISVV-EGLENLTNLEELHIENQRLPPgekltFdPRSLAALsNSLRVLNISGNNID 133

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157820989 150 ALpaelprmTGLRGLWlygnrfeefppallrmgRLHILDLDRNRLGGFPD----LHPLRALRVFSYDHNPVTGPPRVADT 225
Cdd:cd21340  134 SL-------EPLAPLR-----------------NLEQLDASNNQISDLEElldlLSSWPSLRELDLTGNPVCKKPKYRDK 189


                 .
gi 157820989 226 V 226
Cdd:cd21340  190 I 190
LRR_8 pfam13855
Leucine rich repeat;
90-148 1.31e-04

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 39.04  E-value: 1.31e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 157820989   90 PRLTRLYLGGNRLLALPSD-FAQLQSLRCLWIEGNFLRRF-PRPLLRLVALQSLQMGDNRL 148
Cdd:pfam13855   1 PNLRSLDLSNNRLTSLDDGaFKGLSNLKVLDLSNNLLTTLsPGAFSGLPSLRYLDLSGNRL 61
 
Name Accession Description Interval E-value
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
24-218 9.12e-34

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 127.36  E-value: 9.12e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157820989  24 QQLELSGRRLRRLPSAVCALSRLQKLYVSGtglrelpeeieelrelrilaldfNKLERLPDGLCRLPRLTRLYLGGNRLL 103
Cdd:COG4886  116 ESLDLSGNQLTDLPEELANLTNLKELDLSN-----------------------NQLTDLPEPLGNLTNLKSLDLSNNQLT 172

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157820989 104 ALPSDFAQLQSLRCLWIEGNFLRRFPRPLLRLVALQSLQMGDNRLRALPAELPRMTGLRGLWLYGNRFEEFPpALLRMGR 183
Cdd:COG4886  173 DLPEELGNLTNLKELDLSNNQITDLPEPLGNLTNLEELDLSGNQLTDLPEPLANLTNLETLDLSNNQLTDLP-ELGNLTN 251

                        170       180       190
                 ....*....|....*....|....*....|....*
gi 157820989 184 LHILDLDRNRLGGFPDLHPLRALRVFSYDHNPVTG 218
Cdd:COG4886  252 LEELDLSNNQLTDLPPLANLTNLKTLDLSNNQLTD 286
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
74-220 1.49e-32

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 123.89  E-value: 1.49e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157820989  74 LDFNKLERLPDGLCRLPRLTRLYLGGNRLLALPSDFAQLQSLRCLWIEGNFLRRFPRPLLRLVALQSLQMGDNRLRALPA 153
Cdd:COG4886  120 LSGNQLTDLPEELANLTNLKELDLSNNQLTDLPEPLGNLTNLKSLDLSNNQLTDLPEELGNLTNLKELDLSNNQITDLPE 199

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 157820989 154 ELPRMTGLRGLWLYGNRFEEFPPALLRMGRLHILDLDRNRLGGFPDLHPLRALRVFSYDHNPVTGPP 220
Cdd:COG4886  200 PLGNLTNLEELDLSGNQLTDLPEPLANLTNLETLDLSNNQLTDLPELGNLTNLEELDLSNNQLTDLP 266
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
92-217 9.62e-15

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 73.81  E-value: 9.62e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157820989  92 LTRLYLGGNRLLALPSDFAQLQSLRCLWIEGNflrrfpRPLLRLVALQSLQMGDNRLRALPAELPRMTGLRGLWLYGNRF 171
Cdd:COG4886   75 LLLSLLLLSLLLLGLTDLGDLTNLTELDLSGN------EELSNLTNLESLDLSGNQLTDLPEELANLTNLKELDLSNNQL 148

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*..
gi 157820989 172 EEFPPALLRMGRLHILDLDRNRLGGFPD-LHPLRALRVFSYDHNPVT 217
Cdd:COG4886  149 TDLPEPLGNLTNLKSLDLSNNQLTDLPEeLGNLTNLKELDLSNNQIT 195
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
24-151 9.99e-15

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 73.81  E-value: 9.99e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157820989  24 QQLELSGRRLRRLPSAVCALSRLQKLYVSGtglrelpeeieelrelrilaldfNKLERLPDGLCRLPRLTRLYLGGNRLL 103
Cdd:COG4886  185 KELDLSNNQITDLPEPLGNLTNLEELDLSG-----------------------NQLTDLPEPLANLTNLETLDLSNNQLT 241

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*...
gi 157820989 104 ALPSdFAQLQSLRCLWIEGNFLRRFPrPLLRLVALQSLQMGDNRLRAL 151
Cdd:COG4886  242 DLPE-LGNLTNLEELDLSNNQLTDLP-PLANLTNLKTLDLSNNQLTDL 287
PRK15370 PRK15370
type III secretion system effector E3 ubiquitin transferase SlrP;
77-222 3.58e-08

type III secretion system effector E3 ubiquitin transferase SlrP;


Pssm-ID: 185268 [Multi-domain]  Cd Length: 754  Bit Score: 54.32  E-value: 3.58e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157820989  77 NKLERLPDglcRLP-RLTRLYLGGNRLLALPSDFAQlqSLRCLWIEGNFLRRFPRPLLRlvALQSLQMGDNRLRALPAEL 155
Cdd:PRK15370 230 NQLTSIPA---TLPdTIQEMELSINRITELPERLPS--ALQSLDLFHNKISCLPENLPE--ELRYLSVYDNSIRTLPAHL 302

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 157820989 156 PrmTGLRGLWLYGNRFeEFPPALLRMGrLHILDLDRNRLGGFPDLHPlRALRVFSYDHN-----PVTGPPRV 222
Cdd:PRK15370 303 P--SGITHLNVQSNSL-TALPETLPPG-LKTLEAGENALTSLPASLP-PELQVLDVSKNqitvlPETLPPTI 369
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 35-204 1.50e-06

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 49.46  E-value: 1.50e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157820989  35 RLPSAVCALSRLQKLYV-SGTGLRELPEEIEELRELRILALDFNKLE-RLPDGLCRLPRLTRLYLGGNRLLA-LPSDFAQ 111
Cdd:PLN00113 323 KIPVALTSLPRLQVLQLwSNKFSGEIPKNLGKHNNLTVLDLSTNNLTgEIPEGLCSSGNLFKLILFSNSLEGeIPKSLGA 402

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157820989 112 LQSLRCLWIEGN-FLRRFPRPLLRLVALQSLQMGDNRLRA-LPAELPRMTGLRGLWLYGNRFEEFPPALLRMGRLHILDL 189
Cdd:PLN00113 403 CRSLRRVRLQDNsFSGELPSEFTKLPLVYFLDISNNNLQGrINSRKWDMPSLQMLSLARNKFFGGLPDSFGSKRLENLDL 482

                        170       180
                 ....*....|....*....|...
gi 157820989 190 DRNR--------LGGFPDLHPLR 204
Cdd:PLN00113 483 SRNQfsgavprkLGSLSELMQLK 505
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 77-226 1.53e-05

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 45.16  E-value: 1.53e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157820989  77 NKLERLpDGLCRLPRLTRLYLGGNRLLALpSDFAQLQSLRCLWIEGNFLRR-----F-PRPLLRL-VALQSLQMGDNRLR 149
Cdd:cd21340   56 NQIEKI-ENLENLVNLKKLYLGGNRISVV-EGLENLTNLEELHIENQRLPPgekltFdPRSLAALsNSLRVLNISGNNID 133

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157820989 150 ALpaelprmTGLRGLWlygnrfeefppallrmgRLHILDLDRNRLGGFPD----LHPLRALRVFSYDHNPVTGPPRVADT 225
Cdd:cd21340  134 SL-------EPLAPLR-----------------NLEQLDASNNQISDLEElldlLSSWPSLRELDLTGNPVCKKPKYRDK 189


                 .
gi 157820989 226 V 226
Cdd:cd21340  190 I 190
PRK15387 PRK15387
type III secretion system effector E3 ubiquitin transferase SspH2;
79-200 7.18e-05

type III secretion system effector E3 ubiquitin transferase SspH2;


Pssm-ID: 185285 [Multi-domain]  Cd Length: 788  Bit Score: 44.00  E-value: 7.18e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157820989  79 LERLPDGLCRL--------------PRLTRLYLGGNRLLALPSdfaqLQSLRC-LWIEGNFLRRFPR-PllrlVALQSLQ 142
Cdd:PRK15387 277 LPALPSGLCKLwifgnqltslpvlpPGLQELSVSDNQLASLPA----LPSELCkLWAYNNQLTSLPTlP----SGLQELS 348

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 157820989 143 MGDNRLRALPAeLPrmTGLRGLWLYGNRFEEFP--PALLRMgrlhiLDLDRNRLGGFPDL 200
Cdd:PRK15387 349 VSDNQLASLPT-LP--SELYKLWAYNNRLTSLPalPSGLKE-----LIVSGNRLTSLPVL 400
PLN03150 PLN03150
hypothetical protein; Provisional
 105-202 1.22e-04

hypothetical protein; Provisional


Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 43.27  E-value: 1.22e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157820989 105 LPSDFAQLQSLRCLWIEGNFLR-RFPRPLLRLVALQSLQMGDNRLR-ALPAELPRMTGLRGLWLYGNRFEEFPPALLRMG 182
Cdd:PLN03150 434 IPNDISKLRHLQSINLSGNSIRgNIPPSLGSITSLEVLDLSYNSFNgSIPESLGQLTSLRILNLNGNSLSGRVPAALGGR 513

                         90       100
                 ....*....|....*....|...
gi 157820989 183 RLH--ILDLDRNR-LGGFPDLHP 202
Cdd:PLN03150 514 LLHraSFNFTDNAgLCGIPGLRA 536
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 77-218 1.29e-04

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 43.30  E-value: 1.29e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157820989  77 NKLE-RLPDGLCRLPRLTRLYLGGNRLLA-LPSDFAQLQSLRCLWI-EGNFLRRFPRPLLRLVALQSLQMGDNRLRA-LP 152
Cdd:PLN00113 270 NKLSgPIPPSIFSLQKLISLDLSDNSLSGeIPELVIQLQNLEILHLfSNNFTGKIPVALTSLPRLQVLQLWSNKFSGeIP 349

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 157820989 153 AELPRMTGLRGLWLYGNRFE-EFPPALLRMGRLHILDLDRNRLGGF--PDLHPLRALRVFSYDHNPVTG 218
Cdd:PLN00113 350 KNLGKHNNLTVLDLSTNNLTgEIPEGLCSSGNLFKLILFSNSLEGEipKSLGACRSLRRVRLQDNSFSG 418
LRR_8 pfam13855
Leucine rich repeat;
90-148 1.31e-04

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 39.04  E-value: 1.31e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 157820989   90 PRLTRLYLGGNRLLALPSD-FAQLQSLRCLWIEGNFLRRF-PRPLLRLVALQSLQMGDNRL 148
Cdd:pfam13855   1 PNLRSLDLSNNRLTSLDDGaFKGLSNLKVLDLSNNLLTTLsPGAFSGLPSLRYLDLSGNRL 61
PRK15387 PRK15387
type III secretion system effector E3 ubiquitin transferase SspH2;
76-219 1.97e-04

type III secretion system effector E3 ubiquitin transferase SspH2;


Pssm-ID: 185285 [Multi-domain]  Cd Length: 788  Bit Score: 42.84  E-value: 1.97e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157820989  76 FNKLERLPDGLCRLPRLTRLYlggNRLLALPSDFAQlqslrcLWIEGNFLRRFPrplLRLVALQSLQMGDNRLRALPAeL 155
Cdd:PRK15387 254 LTSLPVLPPGLLELSIFSNPL---THLPALPSGLCK------LWIFGNQLTSLP---VLPPGLQELSVSDNQLASLPA-L 320

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 157820989 156 PrmTGLRGLWLYGNRFEEFPPALLRMGRLHILDldrNRLGGFPDLhPLRALRVFSYDHNPVTGP 219
Cdd:PRK15387 321 P--SELCKLWAYNNQLTSLPTLPSGLQELSVSD---NQLASLPTL-PSELYKLWAYNNRLTSLP 378
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 66-218 2.33e-04

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 42.53  E-value: 2.33e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157820989  66 LRELRILALDFNKLE-RLPDGLCRLPRLTRLYLGGNRLLA-LPSDFAQLQSLRCLWIEGNFLR-RFPRPLLRLVALQSLQ 142
Cdd:PLN00113 211 MKSLKWIYLGYNNLSgEIPYEIGGLTSLNHLDLVYNNLTGpIPSSLGNLKNLQYLFLYQNKLSgPIPPSIFSLQKLISLD 290

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157820989 143 MGDNRLRA-LPAELPRMTGLRGLWLYGNRFE-EFPPALLRMGRLHILDLDRNRL-GGFP-DLHPLRALRVFSYDHNPVTG 218
Cdd:PLN00113 291 LSDNSLSGeIPELVIQLQNLEILHLFSNNFTgKIPVALTSLPRLQVLQLWSNKFsGEIPkNLGKHNNLTVLDLSTNNLTG 370
PRK15370 PRK15370
type III secretion system effector E3 ubiquitin transferase SlrP;
6-217 5.71e-04

type III secretion system effector E3 ubiquitin transferase SlrP;


Pssm-ID: 185268 [Multi-domain]  Cd Length: 754  Bit Score: 41.22  E-value: 5.71e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157820989   6 STPDELPSDAEEQLRSGEQQLELSgrrlRRLPSAvcalsrLQKLYVSgtglrelpeeieelrelrilaldFNKL----ER 81
Cdd:PRK15370 234 SIPATLPDTIQEMELSINRITELP----ERLPSA------LQSLDLF-----------------------HNKIsclpEN 280

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157820989  82 LPDGL--------------CRLPR-LTRLYLGGNRLLALPSDFAQlqSLRCLWIEGNFLRRFPRPLLRlvALQSLQMGDN 146
Cdd:PRK15370 281 LPEELrylsvydnsirtlpAHLPSgITHLNVQSNSLTALPETLPP--GLKTLEAGENALTSLPASLPP--ELQVLDVSKN 356

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157820989 147 RLRALPAELPrmTGLRGLWLYGNRFEEFP---PALLRmgrlhILDLDRNRLGGFPDL---------HPLRALrvfsYDHN 214
Cdd:PRK15370 357 QITVLPETLP--PTITTLDVSRNALTNLPenlPAALQ-----IMQASRNNLVRLPESlphfrgegpQPTRII----VEYN 425


                 ...
gi 157820989 215 PVT 217
Cdd:PRK15370 426 PFS 428
RNA1 COG5238
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ...
 89-195 2.26e-03

Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];


Pssm-ID: 444072 [Multi-domain]  Cd Length: 434  Bit Score: 39.39  E-value: 2.26e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157820989  89 LPRLTRLYLGGNRLLALpSDFAQLQSLRCLWIEGNFLRRFprplLRLVALQSLQMGDNRLRALPAELPRMTGLRGLWLYG 168
Cdd:COG5238  143 LIQVLKDPLGGNAVHLL-GLAARLGLLAAISMAKALQNNS----VETVYLGCNQIGDEGIEELAEALTQNTTVTTLWLKR 217

                         90       100       110
                 ....*....|....*....|....*....|..
gi 157820989 169 NRF-----EEFPPALLRMGRLHILDLDRNRLG 195
Cdd:COG5238  218 NPIgdegaEILAEALKGNKSLTTLDLSNNQIG 249
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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