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Conserved domains on  [gi|157823345|ref|NP_001102953|]
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leucine-rich repeat protein 1 [Rattus norvegicus]

Protein Classification

leucine-rich repeat domain-containing protein( domain architecture ID 11469232)

leucine-rich repeat (LRR) domain-containing protein may participate in protein-protein interactions

Gene Ontology:  GO:0005515
PubMed:  11751054|7583641|14747988
SCOP:  4003523

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
163-326 5.34e-33

Leucine-rich repeat (LRR) protein [Transcription];


:

Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 128.51  E-value: 5.34e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157823345 163 SLEHLQASHCRLARVDMRMLCLKSLTKLDLSHNCIKKLPATIGDLTHLQELNLSDNQLESFSVPLCKSTlqkSLQSLDLS 242
Cdd:COG4886  114 NLESLDLSGNQLTDLPEELANLTNLKELDLSNNQLTDLPEPLGNLTNLKSLDLSNNQLTDLPEELGNLT---NLKELDLS 190

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157823345 243 KNKIKALPVQFCQFRELTNLNLNDNELIHLPFKIGRLTNLRFLSAARNKLRNLPCEFKMLSLEYLDLFGNTFEK-PEVLP 321
Cdd:COG4886  191 NNQITDLPEPLGNLTNLEELDLSGNQLTDLPEPLANLTNLETLDLSNNQLTDLPELGNLTNLEELDLSNNQLTDlPPLAN 270


                 ....*
gi 157823345 322 IINLQ 326
Cdd:COG4886  271 LTNLK 275
 
Name Accession Description Interval E-value
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
163-326 5.34e-33

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 128.51  E-value: 5.34e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157823345 163 SLEHLQASHCRLARVDMRMLCLKSLTKLDLSHNCIKKLPATIGDLTHLQELNLSDNQLESFSVPLCKSTlqkSLQSLDLS 242
Cdd:COG4886  114 NLESLDLSGNQLTDLPEELANLTNLKELDLSNNQLTDLPEPLGNLTNLKSLDLSNNQLTDLPEELGNLT---NLKELDLS 190

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157823345 243 KNKIKALPVQFCQFRELTNLNLNDNELIHLPFKIGRLTNLRFLSAARNKLRNLPCEFKMLSLEYLDLFGNTFEK-PEVLP 321
Cdd:COG4886  191 NNQITDLPEPLGNLTNLEELDLSGNQLTDLPEPLANLTNLETLDLSNNQLTDLPELGNLTNLEELDLSNNQLTDlPPLAN 270


                 ....*
gi 157823345 322 IINLQ 326
Cdd:COG4886  271 LTNLK 275
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 164-312 3.77e-13

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 68.27  E-value: 3.77e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157823345 164 LEHLQASHCRLARvdMRML-CLKSLTKLDLSHNCIKKLpATIGDLTHLQELNLSDNQL---ESFSV-PLCKSTLQKSLQS 238
Cdd:cd21340   48 LTHLYLQNNQIEK--IENLeNLVNLKKLYLGGNRISVV-EGLENLTNLEELHIENQRLppgEKLTFdPRSLAALSNSLRV 124

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 157823345 239 LDLSKNKIkalpvqfcqfRELTNLNLndnelihlpfkigrLTNLRFLSAARNKLRNL----PCEFKMLSLEYLDLFGN 312
Cdd:cd21340  125 LNISGNNI----------DSLEPLAP--------------LRNLEQLDASNNQISDLeellDLLSSWPSLRELDLTGN 178
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 185-312 1.16e-07

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 54.08  E-value: 1.16e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157823345 185 KSLTKLDLSHNCIKK-LPATIGDLTHLQELNLSDNQLeSFSVPLCKSTLQKsLQSLDLSKNKIKA-LPVQFCQFRELTNL 262
Cdd:PLN00113 475 KRLENLDLSRNQFSGaVPRKLGSLSELMQLKLSENKL-SGEIPDELSSCKK-LVSLDLSHNQLSGqIPASFSEMPVLSQL 552

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|..
gi 157823345 263 NLNDNELI-HLPFKIGRLTNLRFLSAARNKLR-NLPCEFKMLSLEYLDLFGN 312
Cdd:PLN00113 553 DLSQNQLSgEIPKNLGNVESLVQVNISHNHLHgSLPSTGAFLAINASAVAGN 604
LRR_8 pfam13855
Leucine rich repeat;
163-220 2.35e-06

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 44.44  E-value: 2.35e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 157823345  163 SLEHLQASHCRLARVDMRML-CLKSLTKLDLSHNCIKKL-PATIGDLTHLQELNLSDNQL 220
Cdd:pfam13855   2 NLRSLDLSNNRLTSLDDGAFkGLSNLKVLDLSNNLLTTLsPGAFSGLPSLRYLDLSGNRL 61
 
Name Accession Description Interval E-value
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
163-326 5.34e-33

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 128.51  E-value: 5.34e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157823345 163 SLEHLQASHCRLARVDMRMLCLKSLTKLDLSHNCIKKLPATIGDLTHLQELNLSDNQLESFSVPLCKSTlqkSLQSLDLS 242
Cdd:COG4886  114 NLESLDLSGNQLTDLPEELANLTNLKELDLSNNQLTDLPEPLGNLTNLKSLDLSNNQLTDLPEELGNLT---NLKELDLS 190

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157823345 243 KNKIKALPVQFCQFRELTNLNLNDNELIHLPFKIGRLTNLRFLSAARNKLRNLPCEFKMLSLEYLDLFGNTFEK-PEVLP 321
Cdd:COG4886  191 NNQITDLPEPLGNLTNLEELDLSGNQLTDLPEPLANLTNLETLDLSNNQLTDLPELGNLTNLEELDLSNNQLTDlPPLAN 270


                 ....*
gi 157823345 322 IINLQ 326
Cdd:COG4886  271 LTNLK 275
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
163-333 9.73e-33

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 127.74  E-value: 9.73e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157823345 163 SLEHLQASHCRLARVDMRMLCLKSLTKLDLSHNCIKKLPATIGDLTHLQELNLSDNQLESFSVPLCKSTlqkSLQSLDLS 242
Cdd:COG4886  137 NLKELDLSNNQLTDLPEPLGNLTNLKSLDLSNNQLTDLPEELGNLTNLKELDLSNNQITDLPEPLGNLT---NLEELDLS 213

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157823345 243 KNKIKALPVQFCQFRELTNLNLNDNELIHLPfKIGRLTNLRFLSAARNKLRNLPCEFKMLSLEYLDLFGNTFEKPEVLPI 322
Cdd:COG4886  214 GNQLTDLPEPLANLTNLETLDLSNNQLTDLP-ELGNLTNLEELDLSNNQLTDLPPLANLTNLKTLDLSNNQLTDLKLKEL 292

                        170
                 ....*....|.
gi 157823345 323 INLQVPLTLLE 333
Cdd:COG4886  293 ELLLGLNSLLL 303
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
163-334 1.07e-25

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 108.10  E-value: 1.07e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157823345 163 SLEHLQASHCRLARVDMRMLCLKSLTKLDLSHNCIKKLPATIGDLTHLQELNLSDNQLESFSVPLCKSTlqkSLQSLDLS 242
Cdd:COG4886  160 NLKSLDLSNNQLTDLPEELGNLTNLKELDLSNNQITDLPEPLGNLTNLEELDLSGNQLTDLPEPLANLT---NLETLDLS 236

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157823345 243 KNKIKALPvQFCQFRELTNLNLNDNELIHLPfKIGRLTNLRFLSAARNKLRNLPCEFKMLSLEYLDLFGNTFEKPEVLPI 322
Cdd:COG4886  237 NNQLTDLP-ELGNLTNLEELDLSNNQLTDLP-PLANLTNLKTLDLSNNQLTDLKLKELELLLGLNSLLLLLLLLNLLELL 314

                        170
                 ....*....|..
gi 157823345 323 INLQVPLTLLEA 334
Cdd:COG4886  315 ILLLLLTTLLLL 326
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
182-312 1.04e-17

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 84.60  E-value: 1.04e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157823345 182 LCLKSLTKLDLSHNCIKKLPATIGDLTHLQELNLSDNQ-LESFsvplckstlqKSLQSLDLSKNKIKALPVQFCQFRELT 260
Cdd:COG4886   70 SLLLLLLLSLLLLSLLLLGLTDLGDLTNLTELDLSGNEeLSNL----------TNLESLDLSGNQLTDLPEELANLTNLK 139

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|...
gi 157823345 261 NLNLNDNELIHLPFKIGRLTNLRFLSAARNKLRNLPCEFKML-SLEYLDLFGN 312
Cdd:COG4886  140 ELDLSNNQLTDLPEPLGNLTNLKSLDLSNNQLTDLPEELGNLtNLKELDLSNN 192
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 164-312 3.77e-13

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 68.27  E-value: 3.77e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157823345 164 LEHLQASHCRLARvdMRML-CLKSLTKLDLSHNCIKKLpATIGDLTHLQELNLSDNQL---ESFSV-PLCKSTLQKSLQS 238
Cdd:cd21340   48 LTHLYLQNNQIEK--IENLeNLVNLKKLYLGGNRISVV-EGLENLTNLEELHIENQRLppgEKLTFdPRSLAALSNSLRV 124

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 157823345 239 LDLSKNKIkalpvqfcqfRELTNLNLndnelihlpfkigrLTNLRFLSAARNKLRNL----PCEFKMLSLEYLDLFGN 312
Cdd:cd21340  125 LNISGNNI----------DSLEPLAP--------------LRNLEQLDASNNQISDLeellDLLSSWPSLRELDLTGN 178
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
163-332 4.42e-13

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 70.35  E-value: 4.42e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157823345 163 SLEHLQASHCRLARVDMRMLCLKSLTKLDLSHNCIKKLPAtIGDLTHLQELNLSDNQLESFSvplcKSTLQKSLQSLDLS 242
Cdd:COG4886  206 NLEELDLSGNQLTDLPEPLANLTNLETLDLSNNQLTDLPE-LGNLTNLEELDLSNNQLTDLP----PLANLTNLKTLDLS 280

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157823345 243 KNKIKALPVQFCQFRELTNLNLNDNELIHLPFKIGRLTNLRFLSAARNKLRNLPCEFKMLSLEYLDLFGNTFEKPEVLPI 322
Cdd:COG4886  281 NNQLTDLKLKELELLLGLNSLLLLLLLLNLLELLILLLLLTTLLLLLLLLKGLLVTLTTLALSLSLLALLTLLLLLNLLS 360

                        170
                 ....*....|
gi 157823345 323 INLQVPLTLL 332
Cdd:COG4886  361 LLLTLLLTLG 370
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 185-312 1.16e-07

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 54.08  E-value: 1.16e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157823345 185 KSLTKLDLSHNCIKK-LPATIGDLTHLQELNLSDNQLeSFSVPLCKSTLQKsLQSLDLSKNKIKA-LPVQFCQFRELTNL 262
Cdd:PLN00113 475 KRLENLDLSRNQFSGaVPRKLGSLSELMQLKLSENKL-SGEIPDELSSCKK-LVSLDLSHNQLSGqIPASFSEMPVLSQL 552

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|..
gi 157823345 263 NLNDNELI-HLPFKIGRLTNLRFLSAARNKLR-NLPCEFKMLSLEYLDLFGN 312
Cdd:PLN00113 553 DLSQNQLSgEIPKNLGNVESLVQVNISHNHLHgSLPSTGAFLAINASAVAGN 604
PRK15370 PRK15370
type III secretion system effector E3 ubiquitin transferase SlrP;
186-363 1.19e-07

type III secretion system effector E3 ubiquitin transferase SlrP;


Pssm-ID: 185268 [Multi-domain]  Cd Length: 754  Bit Score: 53.93  E-value: 1.19e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157823345 186 SLTKLDLSHNCIKKLPATIGDLthLQELNLSDNQLesFSVPlckSTLQKSLQSLDLSKNKIKALPvqfcqfreltnlnln 265
Cdd:PRK15370 221 NIKTLYANSNQLTSIPATLPDT--IQEMELSINRI--TELP---ERLPSALQSLDLFHNKISCLP--------------- 278

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157823345 266 DNelihLPfkigrlTNLRFLSAARNKLRNLPCEFKMlSLEYLDLFGNTFEK-PEVLPiINLQVpltlLEACEQAVLSYri 344
Cdd:PRK15370 279 EN----LP------EELRYLSVYDNSIRTLPAHLPS-GITHLNVQSNSLTAlPETLP-PGLKT----LEAGENALTSL-- 340

                        170
                 ....*....|....*....
gi 157823345 345 pygPDIIPYHLcQDLDTAK 363
Cdd:PRK15370 341 ---PASLPPEL-QVLDVSK 355
LRR_RI cd00116
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ...
 162-314 1.86e-07

Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).


Pssm-ID: 238064 [Multi-domain]  Cd Length: 319  Bit Score: 52.36  E-value: 1.86e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157823345 162 YSLEHLQASHCRLARVDMRMLC--LKS----LTKLDLSHN-----CIKKLPATIGDLTHLQELNLSDNQLESFSVP-LCK 229
Cdd:cd00116  108 SSLQELKLNNNGLGDRGLRLLAkgLKDlppaLEKLVLGRNrlegaSCEALAKALRANRDLKELNLANNGIGDAGIRaLAE 187

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157823345 230 S-TLQKSLQSLDLSKNKI-----KALPVQFCQFRELTNLNLNDNEL-------IHLPFKIGrLTNLRFLSAARNKLRNLP 296
Cdd:cd00116  188 GlKANCNLEVLDLNNNGLtdegaSALAETLASLKSLEVLNLGDNNLtdagaaaLASALLSP-NISLLTLSLSCNDITDDG 266

                        170       180
                 ....*....|....*....|....
gi 157823345 297 CE------FKMLSLEYLDLFGNTF 314
Cdd:cd00116  267 AKdlaevlAEKESLLELDLRGNKF 290
PRK15370 PRK15370
type III secretion system effector E3 ubiquitin transferase SlrP;
146-296 2.09e-07

type III secretion system effector E3 ubiquitin transferase SlrP;


Pssm-ID: 185268 [Multi-domain]  Cd Length: 754  Bit Score: 53.16  E-value: 2.09e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157823345 146 MIITSKKDYPLSKNFPYSLEHLQASHCRLARVDMRMLclKSLTKLDLSHNCIKKLPATIGdlTHLQELNLSDNQLESFSv 225
Cdd:PRK15370 267 LDLFHNKISCLPENLPEELRYLSVYDNSIRTLPAHLP--SGITHLNVQSNSLTALPETLP--PGLKTLEAGENALTSLP- 341

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 157823345 226 plckSTLQKSLQSLDLSKNKIKALPVQFCQfrELTNLNLNDNELIHLPFKIGrlTNLRFLSAARNKLRNLP 296
Cdd:PRK15370 342 ----ASLPPELQVLDVSKNQITVLPETLPP--TITTLDVSRNALTNLPENLP--AALQIMQASRNNLVRLP 404
PLN03150 PLN03150
hypothetical protein; Provisional
 200-269 2.17e-07

hypothetical protein; Provisional


Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 52.90  E-value: 2.17e-07
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 157823345 200 LPATIGDLTHLQELNLSDNQLESfSVPLCKSTLqKSLQSLDLSKNKIK-ALPVQFCQFRELTNLNLNDNEL 269
Cdd:PLN03150 434 IPNDISKLRHLQSINLSGNSIRG-NIPPSLGSI-TSLEVLDLSYNSFNgSIPESLGQLTSLRILNLNGNSL 502
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 155-326 6.52e-07

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 51.77  E-value: 6.52e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157823345 155 PLSKNFPYSLEHLQASHCRLA-RVDMRMLCLKSLTKLDLSHNCIK-KLPATIGDLTHLQELNLSDNQLESfSVPLCKSTL 232
Cdd:PLN00113 133 SIPRGSIPNLETLDLSNNMLSgEIPNDIGSFSSLKVLDLGGNVLVgKIPNSLTNLTSLEFLTLASNQLVG-QIPRELGQM 211

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157823345 233 qKSLQSLDLSKNKIKA-LPVQFCQFRELTNLNLNDNELI-HLPFKIGRLTNLRFLSAARNKLRNL--PCEFKMLSLEYLD 308
Cdd:PLN00113 212 -KSLKWIYLGYNNLSGeIPYEIGGLTSLNHLDLVYNNLTgPIPSSLGNLKNLQYLFLYQNKLSGPipPSIFSLQKLISLD 290

                        170       180
                 ....*....|....*....|
gi 157823345 309 LFGNTF--EKPEVlpIINLQ 326
Cdd:PLN00113 291 LSDNSLsgEIPEL--VIQLQ 308
LRR_8 pfam13855
Leucine rich repeat;
163-220 2.35e-06

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 44.44  E-value: 2.35e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 157823345  163 SLEHLQASHCRLARVDMRML-CLKSLTKLDLSHNCIKKL-PATIGDLTHLQELNLSDNQL 220
Cdd:pfam13855   2 NLRSLDLSNNRLTSLDDGAFkGLSNLKVLDLSNNLLTTLsPGAFSGLPSLRYLDLSGNRL 61
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 187-309 2.59e-06

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 49.85  E-value: 2.59e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157823345 187 LTKLDLS-HNCIKKLPATIGDLTHLQELNLSDNQLeSFSVPLCKSTLQKS----------------------LQSLDLSK 243
Cdd:PLN00113  71 VVSIDLSgKNISGKISSAIFRLPYIQTINLSNNQL-SGPIPDDIFTTSSSlrylnlsnnnftgsiprgsipnLETLDLSN 149

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157823345 244 NKIKA-LPVQFCQFRELTNLNLNDNELI-HLPFKIGRLTNLRFLSAARNKLR-NLPCEF-KMLSLEYLDL 309
Cdd:PLN00113 150 NMLSGeIPNDIGSFSSLKVLDLGGNVLVgKIPNSLTNLTSLEFLTLASNQLVgQIPRELgQMKSLKWIYL 219
LRR_8 pfam13855
Leucine rich repeat;
186-246 2.94e-06

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 44.44  E-value: 2.94e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 157823345  186 SLTKLDLSHNCIKKL-PATIGDLTHLQELNLSDNQLESFSvplcKSTLQ--KSLQSLDLSKNKI 246
Cdd:pfam13855   2 NLRSLDLSNNRLTSLdDGAFKGLSNLKVLDLSNNLLTTLS----PGAFSglPSLRYLDLSGNRL 61
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
163-313 3.67e-06

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 48.78  E-value: 3.67e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157823345 163 SLEHLQASHCRLARVDmRMLCLKSLTKLDLSHNCIKKLPaTIGDLTHLQELNLSDNQLESFSVPLCKSTLQ----KSLQS 238
Cdd:COG4886  229 NLETLDLSNNQLTDLP-ELGNLTNLEELDLSNNQLTDLP-PLANLTNLKTLDLSNNQLTDLKLKELELLLGlnslLLLLL 306

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 157823345 239 LDLSKNKIKALPVQFCQFRELTNLNLNDNELIHLPFKIGRLTNLRFLSAARNKLRNLPCEFKMLSLEYLDLFGNT 313
Cdd:COG4886  307 LLNLLELLILLLLLTTLLLLLLLLKGLLVTLTTLALSLSLLALLTLLLLLNLLSLLLTLLLTLGLLGLLEATLLT 381
LRR_8 pfam13855
Leucine rich repeat;
208-269 4.62e-06

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 43.67  E-value: 4.62e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 157823345  208 THLQELNLSDNQLESfsvpLCKSTLQ--KSLQSLDLSKNKIKAL-PVQFCQFRELTNLNLNDNEL 269
Cdd:pfam13855   1 PNLRSLDLSNNRLTS----LDDGAFKglSNLKVLDLSNNLLTTLsPGAFSGLPSLRYLDLSGNRL 61
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 186-314 8.49e-06

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 48.31  E-value: 8.49e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157823345 186 SLTKLDLSHNCIK-KLPATIGDLTHLQELNLSDNQLESF---SVPLCKSTLQKSLQSLDLSKNkikaLPVQFCQFRELTN 261
Cdd:PLN00113 357 NLTVLDLSTNNLTgEIPEGLCSSGNLFKLILFSNSLEGEipkSLGACRSLRRVRLQDNSFSGE----LPSEFTKLPLVYF 432

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 157823345 262 LNLNDNELI-HLPFKIGRLTNLRFLSAARNK-LRNLPCEFKMLSLEYLDLFGNTF 314
Cdd:PLN00113 433 LDISNNNLQgRINSRKWDMPSLQMLSLARNKfFGGLPDSFGSKRLENLDLSRNQF 487
LRR_4 pfam12799
Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a ...
 185-224 6.70e-05

Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a number of proteins with diverse functions and cellular locations. These repeats are usually involved in protein-protein interactions. Each Leucine Rich Repeat is composed of a beta-alpha unit. These units form elongated non-globular structures. Leucine Rich Repeats are often flanked by cysteine rich domains.


Pssm-ID: 463713 [Multi-domain]  Cd Length: 44  Bit Score: 39.92  E-value: 6.70e-05
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|.
gi 157823345  185 KSLTKLDLSHNCIKKLPAtIGDLTHLQELNLSDN-QLESFS 224
Cdd:pfam12799   1 PNLEVLDLSNNQITDIPP-LAKLPNLETLDLSGNnKITDLS 40
PRK15387 PRK15387
type III secretion system effector E3 ubiquitin transferase SspH2;
160-312 1.26e-04

type III secretion system effector E3 ubiquitin transferase SspH2;


Pssm-ID: 185285 [Multi-domain]  Cd Length: 788  Bit Score: 44.38  E-value: 1.26e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157823345 160 FPYSLEHLQASHCRLARVDMrmlCLKSLTKLDLSHNCIKKLPATIgdlTHLQELNLSDNQLESfsVPLCKSTLQK----- 234
Cdd:PRK15387 300 LPPGLQELSVSDNQLASLPA---LPSELCKLWAYNNQLTSLPTLP---SGLQELSVSDNQLAS--LPTLPSELYKlwayn 371

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157823345 235 -----------SLQSLDLSKNKIKALPVQFCQFRELTnlnLNDNELIHLPFKIGRLTNlrfLSAARNKLRNLPCEFKMLS 303
Cdd:PRK15387 372 nrltslpalpsGLKELIVSGNRLTSLPVLPSELKELM---VSGNRLTSLPMLPSGLLS---LSVYRNQLTRLPESLIHLS 445

                        170
                 ....*....|
gi 157823345 304 LE-YLDLFGN 312
Cdd:PRK15387 446 SEtTVNLEGN 455
RNA1 COG5238
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ...
 181-312 1.33e-04

Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];


Pssm-ID: 444072 [Multi-domain]  Cd Length: 434  Bit Score: 44.01  E-value: 1.33e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157823345 181 MLC-LKSLTKLDLSHNCIKKlPATIGDLTHLQE------LNLSDNQLESFSVPLCKSTLQ--KSLQSLDLSKNKI----- 246
Cdd:COG5238  231 ALKgNKSLTTLDLSNNQIGD-EGVIALAEALKNnttvetLYLSGNQIGAEGAIALAKALQgnTTLTSLDLSVNRIgdega 309

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 157823345 247 KALPVQFCQFRELTNLNLNDNelihlpfKIGRlTNLRFLSAARNKLRNlpcefkmlsLEYLDLFGN 312
Cdd:COG5238  310 IALAEGLQGNKTLHTLNLAYN-------GIGA-QGAIALAKALQENTT---------LHSLDLSDN 358
PLN03150 PLN03150
hypothetical protein; Provisional
 186-226 6.26e-04

hypothetical protein; Provisional


Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 42.11  E-value: 6.26e-04
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|..
gi 157823345 186 SLTKLDLSHNCIK-KLPATIGDLTHLQELNLSDNQLeSFSVP 226
Cdd:PLN03150 467 SLEVLDLSYNSFNgSIPESLGQLTSLRILNLNGNSL-SGRVP 507
PRK15387 PRK15387
type III secretion system effector E3 ubiquitin transferase SspH2;
210-321 9.53e-04

type III secretion system effector E3 ubiquitin transferase SspH2;


Pssm-ID: 185285 [Multi-domain]  Cd Length: 788  Bit Score: 41.69  E-value: 9.53e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157823345 210 LQELNLSDNQLESF-SVP--LCK-----------STLQKSLQSLDLSKNKIKALPVQFCQFRELTNLNlndNELIHLPfk 275
Cdd:PRK15387 304 LQELSVSDNQLASLpALPseLCKlwaynnqltslPTLPSGLQELSVSDNQLASLPTLPSELYKLWAYN---NRLTSLP-- 378

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*....
gi 157823345 276 iGRLTNLRFLSAARNKLRNLPC---EFKMLSLEyldlfGNTFEKPEVLP 321
Cdd:PRK15387 379 -ALPSGLKELIVSGNRLTSLPVlpsELKELMVS-----GNRLTSLPMLP 421
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 184-314 3.16e-03

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 39.83  E-value: 3.16e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157823345 184 LKSLTKLDL-SHNCIKKLPATIGDLTHLQELNLSDNQLeSFSVP--LCKstlQKSLQSLDLSKNKIKA-LPVQFCQFREL 259
Cdd:PLN00113 307 LQNLEILHLfSNNFTGKIPVALTSLPRLQVLQLWSNKF-SGEIPknLGK---HNNLTVLDLSTNNLTGeIPEGLCSSGNL 382

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 157823345 260 TNLNLNDNELI-HLPFKIGRLTNLRFLSAARNKLR-NLPCEFKMLSLEY-LDLFGNTF 314
Cdd:PLN00113 383 FKLILFSNSLEgEIPKSLGACRSLRRVRLQDNSFSgELPSEFTKLPLVYfLDISNNNL 440
RNA1 COG5238
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ...
 185-269 5.16e-03

Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];


Pssm-ID: 444072 [Multi-domain]  Cd Length: 434  Bit Score: 39.00  E-value: 5.16e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157823345 185 KSLTKLDLSHNCI-----KKLPATIGDLTHLQELNLSDNQLESFSV-PLCKS-TLQKSLQSLDLSKNKIKALPVQFC--- 254
Cdd:COG5238  320 KTLHTLNLAYNGIgaqgaIALAKALQENTTLHSLDLSDNQIGDEGAiALAKYlEGNTTLRELNLGKNNIGKQGAEALida 399

                         90
                 ....*....|....*.
gi 157823345 255 -QFRELTNLNLNDNEL 269
Cdd:COG5238  400 lQTNRLHTLILDGNLI 415
LRR_4 pfam12799
Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a ...
 234-270 9.13e-03

Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a number of proteins with diverse functions and cellular locations. These repeats are usually involved in protein-protein interactions. Each Leucine Rich Repeat is composed of a beta-alpha unit. These units form elongated non-globular structures. Leucine Rich Repeats are often flanked by cysteine rich domains.


Pssm-ID: 463713 [Multi-domain]  Cd Length: 44  Bit Score: 34.14  E-value: 9.13e-03
                          10        20        30
                  ....*....|....*....|....*....|....*..
gi 157823345  234 KSLQSLDLSKNKIKALPVqFCQFRELTNLNLNDNELI 270
Cdd:pfam12799   1 PNLEVLDLSNNQITDIPP-LAKLPNLETLDLSGNNKI 36
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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