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Conserved domains on  [gi|1243057505|ref|NP_001342398|]
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golgin subfamily A member 8T [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
GOLGA2L5 super family cl25923
Putative golgin subfamily A member 2-like protein 5; The function of the GOLGA2L5 protein ...
 226-510 8.83e-38

Putative golgin subfamily A member 2-like protein 5; The function of the GOLGA2L5 protein family remains unknown. This family of proteins is thought to be found in the Golgi apparatus of eukaryotes.


The actual alignment was detected with superfamily member pfam15070:

Pssm-ID: 464485 [Multi-domain]  Cd Length: 521  Bit Score: 147.13  E-value: 8.83e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243057505 226 QLKESFQQVQLERDEYSEHLKGERARWQQRMRKMSQEICTLKKEKQQDMRRVEELERSLSKLKNQMAEPLPPEPPAVP-- 303
Cdd:pfam15070   1 QLMESLKQLQTERDQYAENLKEEGAVWQQKMQQLSEQVRTLREEKERSVSQVQELETSLAELKNQAAVPPAEEEQPPAgp 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243057505 304 SEVE------LQHLRKELERVAGELQAQVKKNQRISLLNQRQEERIQEQEERLRKQEERIQEQHKSL------------- 364
Cdd:pfam15070  81 SEEEqrlqeeAEQLQKELEALAGQLQAQVQDNEQLSRLNQEQEQRLLELERAAERWGEQAEDRKQILedmqsdratisra 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243057505 365 --------QQLAKPQSVFEEPNNEN---KNALQLEQQVK--------ELQEKLGE------------------------- 400
Cdd:pfam15070 161 lsqnrelkEQLAELQNGFVKLTNENmelTSALQSEQHVKkelakklgQLQEELGElketlelksqeaqslqeqrdqylah 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243057505 401 ------------------------------------------------------EHLEAASQQNQQLTAQLSLMALPGEG 426
Cdd:pfam15070 241 lqqyvaayqqlasekeelhkqyllqtqlmdrlqheevqgkvaaemarqelqetqERLEALTQQNQQLQAQLSLLANPGEG 320

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243057505 427 HGGEHlDSEGEEAPQPMPSVPEDLESREAMSSFMDHL-----KEKADLSELVKKElcfihhwrDRRHQKTHHLLS----E 497
Cdd:pfam15070 321 DGLES-EEEEEEAPRPSLSIPEDFESREAMVAFFNSAlaqaeEERAELRRQLKEQ--------KRRCRRLAQQAApaqeE 391

                         410
                  ....*....|...
gi 1243057505 498 PGGCAKDAALGGG 510
Cdd:pfam15070 392 PEHEAHAPGTGGD 404
GM130_C pfam19046
GM130 C-terminal binding motif; This entry represents the C-terminal motif from the GM130 ...
 592-631 1.30e-14

GM130 C-terminal binding motif; This entry represents the C-terminal motif from the GM130 protein that is bound by the GRASP65 PDZ domain pfam04495.


:

Pssm-ID: 465957  Cd Length: 46  Bit Score: 68.18  E-value: 1.30e-14
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*.
gi 1243057505 592 PLLDKPTAQPIV------QDHQEHPGLGSNCCVPFLCWAWLPRRRR 631
Cdd:pfam19046   1 SPPENPTAQQIMqllpeiQNPQEHPGLGSNPCIPFFYRADENDEVK 46
EnvC super family cl34844
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 86-290 2.33e-07

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


The actual alignment was detected with superfamily member COG4942:

Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 53.23  E-value: 2.33e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243057505  86 LDSRSVEISQLKNTIKSLKQQKKQVEHQLEEEKKANNKKQKAKRVLEVQIQTLNIQKEELNTDLYHMKRSLryfEEKSKD 165
Cdd:COG4942    29 LEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAEL---EAQKEE 105

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243057505 166 LA--VRLQHSLQRKGELESVLSNVMATQKKKA----NQLSSRSKARTEwKLEQSMREETLLKVQLTQLKESFQQVQLERD 239
Cdd:COG4942   106 LAelLRALYRLGRQPPLALLLSPEDFLDAVRRlqylKYLAPARREQAE-ELRADLAELAALRAELEAERAELEALLAELE 184

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1243057505 240 EYSEHLKGERARWQQRMRKMSQEICTLKKEKQQDMRRVEELERSLSKLKNQ 290
Cdd:COG4942   185 EERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAE 235
 
Name Accession Description Interval E-value
GOLGA2L5 pfam15070
Putative golgin subfamily A member 2-like protein 5; The function of the GOLGA2L5 protein ...
 226-510 8.83e-38

Putative golgin subfamily A member 2-like protein 5; The function of the GOLGA2L5 protein family remains unknown. This family of proteins is thought to be found in the Golgi apparatus of eukaryotes.


Pssm-ID: 464485 [Multi-domain]  Cd Length: 521  Bit Score: 147.13  E-value: 8.83e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243057505 226 QLKESFQQVQLERDEYSEHLKGERARWQQRMRKMSQEICTLKKEKQQDMRRVEELERSLSKLKNQMAEPLPPEPPAVP-- 303
Cdd:pfam15070   1 QLMESLKQLQTERDQYAENLKEEGAVWQQKMQQLSEQVRTLREEKERSVSQVQELETSLAELKNQAAVPPAEEEQPPAgp 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243057505 304 SEVE------LQHLRKELERVAGELQAQVKKNQRISLLNQRQEERIQEQEERLRKQEERIQEQHKSL------------- 364
Cdd:pfam15070  81 SEEEqrlqeeAEQLQKELEALAGQLQAQVQDNEQLSRLNQEQEQRLLELERAAERWGEQAEDRKQILedmqsdratisra 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243057505 365 --------QQLAKPQSVFEEPNNEN---KNALQLEQQVK--------ELQEKLGE------------------------- 400
Cdd:pfam15070 161 lsqnrelkEQLAELQNGFVKLTNENmelTSALQSEQHVKkelakklgQLQEELGElketlelksqeaqslqeqrdqylah 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243057505 401 ------------------------------------------------------EHLEAASQQNQQLTAQLSLMALPGEG 426
Cdd:pfam15070 241 lqqyvaayqqlasekeelhkqyllqtqlmdrlqheevqgkvaaemarqelqetqERLEALTQQNQQLQAQLSLLANPGEG 320

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243057505 427 HGGEHlDSEGEEAPQPMPSVPEDLESREAMSSFMDHL-----KEKADLSELVKKElcfihhwrDRRHQKTHHLLS----E 497
Cdd:pfam15070 321 DGLES-EEEEEEAPRPSLSIPEDFESREAMVAFFNSAlaqaeEERAELRRQLKEQ--------KRRCRRLAQQAApaqeE 391

                         410
                  ....*....|...
gi 1243057505 498 PGGCAKDAALGGG 510
Cdd:pfam15070 392 PEHEAHAPGTGGD 404
GM130_C pfam19046
GM130 C-terminal binding motif; This entry represents the C-terminal motif from the GM130 ...
 592-631 1.30e-14

GM130 C-terminal binding motif; This entry represents the C-terminal motif from the GM130 protein that is bound by the GRASP65 PDZ domain pfam04495.


Pssm-ID: 465957  Cd Length: 46  Bit Score: 68.18  E-value: 1.30e-14
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*.
gi 1243057505 592 PLLDKPTAQPIV------QDHQEHPGLGSNCCVPFLCWAWLPRRRR 631
Cdd:pfam19046   1 SPPENPTAQQIMqllpeiQNPQEHPGLGSNPCIPFFYRADENDEVK 46
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 80-416 1.50e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 64.57  E-value: 1.50e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243057505  80 QERAVVLDSRSVEISQLKNTIKSLKQQKKQVEHQLEEEKKANNKKQKAKRVLEVQIQTLNIQKEELNTDLYHMKRSLRYF 159
Cdd:COG1196   228 ELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARL 307

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243057505 160 EEKSKDLAVRLQHSLQRKGELEsvlsnvmatqkkkaNQLSSRSKARTEWKLEQSMREETLLKVQLtQLKESFQQVQLERD 239
Cdd:COG1196   308 EERRRELEERLEELEEELAELE--------------EELEELEEELEELEEELEEAEEELEEAEA-ELAEAEEALLEAEA 372

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243057505 240 EYSEHLKGERARWQQRMRKMSQEIcTLKKEKQQDMRRVEELERSLSKLKNQMAEPLPPEPPAVPSEVELQHLRKELERVA 319
Cdd:COG1196   373 ELAEAEEELEELAEELLEALRAAA-ELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEE 451

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243057505 320 GELQAQVKKNQRISLLNQRQEERIQEQEERLRKQEERIQEQHKSLQQLAK-----PQSVFEEPNNENKN----ALQLEQQ 390
Cdd:COG1196   452 AELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEAdyegfLEGVKAALLLAGLRglagAVAVLIG 531

                         330       340
                  ....*....|....*....|....*.
gi 1243057505 391 VKELQEKLGEEHLEAASQQNQQLTAQ 416
Cdd:COG1196   532 VEAAYEAALEAALAAALQNIVVEDDE 557
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 80-374 6.84e-09

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 59.30  E-value: 6.84e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243057505   80 QERAVVLDSRSVEISQLKNTIKSLKQQKKQVEHQLEEEKKANNKKQKAKRVLEVQIQTLNIQKEELNTDLYHMKRSLRYF 159
Cdd:TIGR02168  221 ELRELELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRL 300

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243057505  160 EEKSKDLAVRLQHSLQRKGELESVLsnvmaTQKKKANQLSSRSKARTEWKLEQSMREETLLKVQLTQLKESFQQV---QL 236
Cdd:TIGR02168  301 EQQKQILRERLANLERQLEELEAQL-----EELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELesrLE 375

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243057505  237 ERDEYSEHLKGERARWQQRMRKMSQEICTLKKEKQQDMRRVEELERSLSKL-----KNQMAEPLPPEPPAVPSEVELQHL 311
Cdd:TIGR02168  376 ELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELlkkleEAELKELQAELEELEEELEELQEE 455

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1243057505  312 RKELERVAGELQAQVKKNQRISLLNQRQEERIQEQEERLRKQEERIQEQHKSLQQLAKPQSVF 374
Cdd:TIGR02168  456 LERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGL 518
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 86-290 2.33e-07

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 53.23  E-value: 2.33e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243057505  86 LDSRSVEISQLKNTIKSLKQQKKQVEHQLEEEKKANNKKQKAKRVLEVQIQTLNIQKEELNTDLYHMKRSLryfEEKSKD 165
Cdd:COG4942    29 LEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAEL---EAQKEE 105

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243057505 166 LA--VRLQHSLQRKGELESVLSNVMATQKKKA----NQLSSRSKARTEwKLEQSMREETLLKVQLTQLKESFQQVQLERD 239
Cdd:COG4942   106 LAelLRALYRLGRQPPLALLLSPEDFLDAVRRlqylKYLAPARREQAE-ELRADLAELAALRAELEAERAELEALLAELE 184

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1243057505 240 EYSEHLKGERARWQQRMRKMSQEICTLKKEKQQDMRRVEELERSLSKLKNQ 290
Cdd:COG4942   185 EERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAE 235
PRK11281 PRK11281
mechanosensitive channel MscK;
216-416 9.34e-04

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 42.59  E-value: 9.34e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243057505  216 EETLLKVQLTQLKESFQQVQLERDEySEHLKGERARWQQRMRKMSQEICTLKKEKQQDMRR------VEELERSLSKLKN 289
Cdd:PRK11281    57 EDKLVQQDLEQTLALLDKIDRQKEE-TEQLKQQLAQAPAKLRQAQAELEALKDDNDEETREtlstlsLRQLESRLAQTLD 135

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243057505  290 QMAEPLPPEPPAVPSEVELQhlrKELERVAGELQAQVKKNQRISLLNQRQEERIQEQEERLRKQ--------EERIQEQH 361
Cdd:PRK11281   136 QLQNAQNDLAEYNSQLVSLQ---TQPERAQAALYANSQRLQQIRNLLKGGKVGGKALRPSQRVLlqaeqallNAQNDLQR 212

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1243057505  362 KSLQQLAKPQSVFEEPNNE-NKNALQLEQQVKELQEKLGEEHLEAASQQNQQLTAQ 416
Cdd:PRK11281   213 KSLEGNTQLQDLLQKQRDYlTARIQRLEHQLQLLQEAINSKRLTLSEKTVQEAQSQ 268
 
Name Accession Description Interval E-value
GOLGA2L5 pfam15070
Putative golgin subfamily A member 2-like protein 5; The function of the GOLGA2L5 protein ...
 226-510 8.83e-38

Putative golgin subfamily A member 2-like protein 5; The function of the GOLGA2L5 protein family remains unknown. This family of proteins is thought to be found in the Golgi apparatus of eukaryotes.


Pssm-ID: 464485 [Multi-domain]  Cd Length: 521  Bit Score: 147.13  E-value: 8.83e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243057505 226 QLKESFQQVQLERDEYSEHLKGERARWQQRMRKMSQEICTLKKEKQQDMRRVEELERSLSKLKNQMAEPLPPEPPAVP-- 303
Cdd:pfam15070   1 QLMESLKQLQTERDQYAENLKEEGAVWQQKMQQLSEQVRTLREEKERSVSQVQELETSLAELKNQAAVPPAEEEQPPAgp 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243057505 304 SEVE------LQHLRKELERVAGELQAQVKKNQRISLLNQRQEERIQEQEERLRKQEERIQEQHKSL------------- 364
Cdd:pfam15070  81 SEEEqrlqeeAEQLQKELEALAGQLQAQVQDNEQLSRLNQEQEQRLLELERAAERWGEQAEDRKQILedmqsdratisra 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243057505 365 --------QQLAKPQSVFEEPNNEN---KNALQLEQQVK--------ELQEKLGE------------------------- 400
Cdd:pfam15070 161 lsqnrelkEQLAELQNGFVKLTNENmelTSALQSEQHVKkelakklgQLQEELGElketlelksqeaqslqeqrdqylah 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243057505 401 ------------------------------------------------------EHLEAASQQNQQLTAQLSLMALPGEG 426
Cdd:pfam15070 241 lqqyvaayqqlasekeelhkqyllqtqlmdrlqheevqgkvaaemarqelqetqERLEALTQQNQQLQAQLSLLANPGEG 320

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243057505 427 HGGEHlDSEGEEAPQPMPSVPEDLESREAMSSFMDHL-----KEKADLSELVKKElcfihhwrDRRHQKTHHLLS----E 497
Cdd:pfam15070 321 DGLES-EEEEEEAPRPSLSIPEDFESREAMVAFFNSAlaqaeEERAELRRQLKEQ--------KRRCRRLAQQAApaqeE 391

                         410
                  ....*....|...
gi 1243057505 498 PGGCAKDAALGGG 510
Cdd:pfam15070 392 PEHEAHAPGTGGD 404
GM130_C pfam19046
GM130 C-terminal binding motif; This entry represents the C-terminal motif from the GM130 ...
 592-631 1.30e-14

GM130 C-terminal binding motif; This entry represents the C-terminal motif from the GM130 protein that is bound by the GRASP65 PDZ domain pfam04495.


Pssm-ID: 465957  Cd Length: 46  Bit Score: 68.18  E-value: 1.30e-14
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*.
gi 1243057505 592 PLLDKPTAQPIV------QDHQEHPGLGSNCCVPFLCWAWLPRRRR 631
Cdd:pfam19046   1 SPPENPTAQQIMqllpeiQNPQEHPGLGSNPCIPFFYRADENDEVK 46
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 80-416 1.50e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 64.57  E-value: 1.50e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243057505  80 QERAVVLDSRSVEISQLKNTIKSLKQQKKQVEHQLEEEKKANNKKQKAKRVLEVQIQTLNIQKEELNTDLYHMKRSLRYF 159
Cdd:COG1196   228 ELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARL 307

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243057505 160 EEKSKDLAVRLQHSLQRKGELEsvlsnvmatqkkkaNQLSSRSKARTEWKLEQSMREETLLKVQLtQLKESFQQVQLERD 239
Cdd:COG1196   308 EERRRELEERLEELEEELAELE--------------EELEELEEELEELEEELEEAEEELEEAEA-ELAEAEEALLEAEA 372

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243057505 240 EYSEHLKGERARWQQRMRKMSQEIcTLKKEKQQDMRRVEELERSLSKLKNQMAEPLPPEPPAVPSEVELQHLRKELERVA 319
Cdd:COG1196   373 ELAEAEEELEELAEELLEALRAAA-ELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEE 451

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243057505 320 GELQAQVKKNQRISLLNQRQEERIQEQEERLRKQEERIQEQHKSLQQLAK-----PQSVFEEPNNENKN----ALQLEQQ 390
Cdd:COG1196   452 AELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEAdyegfLEGVKAALLLAGLRglagAVAVLIG 531

                         330       340
                  ....*....|....*....|....*.
gi 1243057505 391 VKELQEKLGEEHLEAASQQNQQLTAQ 416
Cdd:COG1196   532 VEAAYEAALEAALAAALQNIVVEDDE 557
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 80-374 6.84e-09

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 59.30  E-value: 6.84e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243057505   80 QERAVVLDSRSVEISQLKNTIKSLKQQKKQVEHQLEEEKKANNKKQKAKRVLEVQIQTLNIQKEELNTDLYHMKRSLRYF 159
Cdd:TIGR02168  221 ELRELELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRL 300

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243057505  160 EEKSKDLAVRLQHSLQRKGELESVLsnvmaTQKKKANQLSSRSKARTEWKLEQSMREETLLKVQLTQLKESFQQV---QL 236
Cdd:TIGR02168  301 EQQKQILRERLANLERQLEELEAQL-----EELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELesrLE 375

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243057505  237 ERDEYSEHLKGERARWQQRMRKMSQEICTLKKEKQQDMRRVEELERSLSKL-----KNQMAEPLPPEPPAVPSEVELQHL 311
Cdd:TIGR02168  376 ELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELlkkleEAELKELQAELEELEEELEELQEE 455

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1243057505  312 RKELERVAGELQAQVKKNQRISLLNQRQEERIQEQEERLRKQEERIQEQHKSLQQLAKPQSVF 374
Cdd:TIGR02168  456 LERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGL 518
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 97-455 7.89e-08

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 55.83  E-value: 7.89e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243057505   97 KNTIKSLKQQKKQVEHQLEEEKKANNKKQKAKRVLEVQIQTLNIQKEELNTDLYHMKRSLRYFEEKSKDLAVRLQHSLQR 176
Cdd:TIGR02168  676 RREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKE 755

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243057505  177 KGELEsvlsnvmatqKKKANQLSSRSKARTEWKLeqsmreetlLKVQLTQLKESFQQVQLERDEYSEHLKGERARWQQrm 256
Cdd:TIGR02168  756 LTELE----------AEIEELEERLEEAEEELAE---------AEAEIEELEAQIEQLKEELKALREALDELRAELTL-- 814

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243057505  257 rkmsqeictLKKEKQQDMRRVEELERSLSKLKNQMAEPLPPEPPAVPSEVELQHLRKELERVAGELQAQVKKNQrislln 336
Cdd:TIGR02168  815 ---------LNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALL------ 879

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243057505  337 qrqeeriqeqeERLRKQEERIQEQHKSLQQLAkpqsvfEEPNNENKNALQLEQQVKELQEKLG--EEHLEAASQQNQQLT 414
Cdd:TIGR02168  880 -----------NERASLEEALALLRSELEELS------EELRELESKRSELRRELEELREKLAqlELRLEGLEVRIDNLQ 942

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|.
gi 1243057505  415 AQLSlmalpgeghggEHLDSEGEEAPQPMPSVPEDLESREA 455
Cdd:TIGR02168  943 ERLS-----------EEYSLTLEEAEALENKIEDDEEEARR 972
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 86-290 2.33e-07

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 53.23  E-value: 2.33e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243057505  86 LDSRSVEISQLKNTIKSLKQQKKQVEHQLEEEKKANNKKQKAKRVLEVQIQTLNIQKEELNTDLYHMKRSLryfEEKSKD 165
Cdd:COG4942    29 LEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAEL---EAQKEE 105

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243057505 166 LA--VRLQHSLQRKGELESVLSNVMATQKKKA----NQLSSRSKARTEwKLEQSMREETLLKVQLTQLKESFQQVQLERD 239
Cdd:COG4942   106 LAelLRALYRLGRQPPLALLLSPEDFLDAVRRlqylKYLAPARREQAE-ELRADLAELAALRAELEAERAELEALLAELE 184

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1243057505 240 EYSEHLKGERARWQQRMRKMSQEICTLKKEKQQDMRRVEELERSLSKLKNQ 290
Cdd:COG4942   185 EERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAE 235
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 131-419 5.39e-07

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 53.02  E-value: 5.39e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243057505 131 LEVQIQTLNIQKE------ELNTDLYHMKRSLRYFEEKskDLAVRLQHSLQRKGELESVLSNVMATQKKKANQLSSRSKA 204
Cdd:COG1196   198 LERQLEPLERQAEkaeryrELKEELKELEAELLLLKLR--ELEAELEELEAELEELEAELEELEAELAELEAELEELRLE 275

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243057505 205 RTE--WKLEQSMREETLLKVQLTQLKESFQQVQLERDEYS---EHLKGERARWQQRMRKMSQEICTLKKEKQQDMRRVEE 279
Cdd:COG1196   276 LEEleLELEEAQAEEYELLAELARLEQDIARLEERRRELEerlEELEEELAELEEELEELEEELEELEEELEEAEEELEE 355

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243057505 280 LERSLSKLKNQMAEPLPPEPPAVPSEVELQHLRKELERVAGELQAQVKKNQRisllnqrQEERIQEQEERLRKQEERIQE 359
Cdd:COG1196   356 AEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEE-------AEEALLERLERLEEELEELEE 428

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243057505 360 QHKSLQQLAKPQSVFEEpnNENKNALQLEQQVKELQEKLGEEHLEAASQQNQQLTAQLSL 419
Cdd:COG1196   429 ALAELEEEEEEEEEALE--EAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEEL 486
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 100-417 1.06e-06

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 51.98  E-value: 1.06e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243057505  100 IKSLKQQKKQVEHQLEEEKKANNKKQKAKRVLEVQIQTLNIQKEElnTDLYHMKRSlryfEEKSKDLAVRLQHSLQRKGE 179
Cdd:TIGR02168  167 ISKYKERRKETERKLERTRENLDRLEDILNELERQLKSLERQAEK--AERYKELKA----ELRELELALLVLRLEELREE 240

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243057505  180 LESVLSNVMATQKKKaNQLSSRSKARTEwKLEQSMREETLLKVQLTQLKESFQQVQLERDEysehLKGERARWQQRMRKM 259
Cdd:TIGR02168  241 LEELQEELKEAEEEL-EELTAELQELEE-KLEELRLEVSELEEEIEELQKELYALANEISR----LEQQKQILRERLANL 314

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243057505  260 SQEICTLKKEKQQDMRRVEELERSLSKLKNQMAEPLPPEPPAVPSEVELQHLRKELERVAGELQAQVKKNQRISLLNQRQ 339
Cdd:TIGR02168  315 ERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQ 394

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1243057505  340 EERIQEQEERLRKQEERIQEQHKSLQQLAKPQSVFEEPNNENKNALQLEQQVKELQEKlgEEHLEAASQQNQQLTAQL 417
Cdd:TIGR02168  395 IASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEEL--QEELERLEEALEELREEL 470
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 98-291 8.76e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 48.22  E-value: 8.76e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243057505  98 NTIKSLKQQKKQVEHQLEEEKKANNKKQKAKRVLEVQIQTLNIQKEELNTDLYHMKRSLRYFEEKSKDLAVRLQHSLQRK 177
Cdd:COG4942    20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAEL 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243057505 178 GELESVLSNVMATQKKKANQ------LSSRSKARTEWKLE----------QSMREETLLKVQLTQLKESFQQVQLERDEY 241
Cdd:COG4942   100 EAQKEELAELLRALYRLGRQpplallLSPEDFLDAVRRLQylkylaparrEQAEELRADLAELAALRAELEAERAELEAL 179

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 1243057505 242 SEHLKGERARWQQRMRKMSQEICTLKKEKQQDMRRVEELERSLSKLKNQM 291
Cdd:COG4942   180 LAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALI 229
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 157-475 1.98e-05

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 47.76  E-value: 1.98e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243057505  157 RYFEEKSKDLAVRLQhSLQRkgELESVLSNVmATQKKKANQLSSRSKARTEwKLEQSMREETLLKVQLTQLKEsfQQVQL 236
Cdd:TIGR02169  670 RSEPAELQRLRERLE-GLKR--ELSSLQSEL-RRIENRLDELSQELSDASR-KIGEIEKEIEQLEQEEEKLKE--RLEEL 742

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243057505  237 ERDeysehlkgerarwqqrMRKMSQEICTLKKEKQQDMRRVEELERSLSKLKNQMAEPLPPEPPAVPSEV--ELQHLRKE 314
Cdd:TIGR02169  743 EED----------------LSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLSHSRIPEIqaELSKLEEE 806

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243057505  315 LERVAGELQAQVKKNQRISLLNQRQEERIQEQEERLRKQEERI----QEQHKSLQQLAKPQSVFEEPNNE---------- 380
Cdd:TIGR02169  807 VSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIksieKEIENLNGKKEELEEELEELEAAlrdlesrlgd 886

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243057505  381 -NKNALQLEQQVKELQEKLGE--EHLEAASQQNQQLTAQLSlmALPGEGHGGEHLDSEGEEAPQPMPSVPEDLESREAMS 457
Cdd:TIGR02169  887 lKKERDELEAQLRELERKIEEleAQIEKKRKRLSELKAKLE--ALEEELSEIEDPKGEDEEIPEEELSLEDVQAELQRVE 964

                          330       340       350
                   ....*....|....*....|....*....|
gi 1243057505  458 SFMDHL------------KEKADLSELVKK 475
Cdd:TIGR02169  965 EEIRALepvnmlaiqeyeEVLKRLDELKEK 994
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
113-424 2.97e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 43.99  E-value: 2.97e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243057505 113 QLEEEKKANNKKQKAKRVLEVQIQTLNIQKEELNTDLYHMKRSLRyfeekSKDLAVRLQHSLQRKGELESVLSNVMAtqk 192
Cdd:COG4717    75 ELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELE-----KLEKLLQLLPLYQELEALEAELAELPE--- 146

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243057505 193 kKANQLSSRSKARTEWKLEQSMREETLLKVQlTQLKESFQQVQLERDEYSEHLKGERARWQQRMRKMSQEICTLKKEKQQ 272
Cdd:COG4717   147 -RLEELEERLEELRELEEELEELEAELAELQ-EELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEE 224

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243057505 273 DMRRVEELERSLSKLKNQMAEPLPPEPPAVPSEV-----ELQHLRKELERVAGELQAQVKKNQRISLLNQRQEERIQEQE 347
Cdd:COG4717   225 LEEELEQLENELEAAALEERLKEARLLLLIAAALlallgLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEA 304

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1243057505 348 ERLRKQEERIQEQHKSLQQLAKPQSVfeEPNNENKNALQLEQQVKELQEKLGE-EHLEAASQQNQQLTAQLSLMALPG 424
Cdd:COG4717   305 EELQALPALEELEEEELEELLAALGL--PPDLSPEELLELLDRIEELQELLREaEELEEELQLEELEQEIAALLAEAG 380
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 92-417 3.84e-04

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 43.47  E-value: 3.84e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243057505  92 EISQLKNTIKSLKQQKKQVEHQLEEEKKANNKKQKAKRVLEVQIQTLNIQKEELNTD-----LYHMKRSLRYFEEKSKDL 166
Cdd:TIGR04523 247 EISNTQTQLNQLKDEQNKIKKQLSEKQKELEQNNKKIKELEKQLNQLKSEISDLNNQkeqdwNKELKSELKNQEKKLEEI 326

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243057505 167 AVRLQHSLQRKGELESVLSNVmatQKKKANQLSSRSKARTEwkLEQSMREETLLKVQLTQLKESFQQVQLERDEysehLK 246
Cdd:TIGR04523 327 QNQISQNNKIISQLNEQISQL---KKELTNSESENSEKQRE--LEEKQNEIEKLKKENQSYKQEIKNLESQIND----LE 397

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243057505 247 GERARWQQRMRKMSQEICTLKKEKQQDMRRVEELERSLSKLKNQMAEPLPPEPPAVPSEVELQHLRKELERVAGELQAQV 326
Cdd:TIGR04523 398 SKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSI 477

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243057505 327 KKNQRISLLNQRQEERIQEQEERLRKQEERIQEQHKSLQQlaKPQSVFEEPNNENKNALQLEQQVKELQEKLGE------ 400
Cdd:TIGR04523 478 NKIKQNLEQKQKELKSKEKELKKLNEEKKELEEKVKDLTK--KISSLKEKIEKLESEKKEKESKISDLEDELNKddfelk 555

                         330
                  ....*....|....*...
gi 1243057505 401 -EHLEAASQQNQQLTAQL 417
Cdd:TIGR04523 556 kENLEKEIDEKNKEIEEL 573
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 103-468 7.99e-04

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 42.79  E-value: 7.99e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243057505 103 LKQQKKQVEHQLEEEKKANNKKQKAKRVLEVQIQTLNIQKEELNTDLYHMKRSLRYFEEKSKDLAVRLQHSLQRKGELES 182
Cdd:pfam05483 217 LKEDHEKIQHLEEEYKKEINDKEKQVSLLLIQITEKENKMKDLTFLLEESRDKANQLEEKTKLQDENLKELIEKKDHLTK 296

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243057505 183 VLSNVmatqkkkanQLSSRSKARTEWKLEQSMREETLLKVQLTQLKESfqqvqlerdeYSEHLKGERARWQQRMRKMSQE 262
Cdd:pfam05483 297 ELEDI---------KMSLQRSMSTQKALEEDLQIATKTICQLTEEKEA----------QMEELNKAKAAHSFVVTEFEAT 357

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243057505 263 ICTLKKEKQQDMRRVEELERSLS----KLKNQMAEPLPPEPPAVPSEVELQhlrkELERVAGELQAQVKKNQRISLLNQR 338
Cdd:pfam05483 358 TCSLEELLRTEQQRLEKNEDQLKiitmELQKKSSELEEMTKFKNNKEVELE----ELKKILAEDEKLLDEKKQFEKIAEE 433

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243057505 339 QEERIQEQEERLRKQEERIQEQHKSLQQLAKPQSVFEEPNNENKNALQLEQqvkeLQEKLGEEHLEAASQQNQQLTAQLS 418
Cdd:pfam05483 434 LKGKEQELIFLLQAREKEIHDLEIQLTAIKTSEEHYLKEVEDLKTELEKEK----LKNIELTAHCDKLLLENKELTQEAS 509

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1243057505 419 LMALPGEGHGGEHLDSEGEEapQPMPSVPEDLESREA-----MSSFMDHLKEKAD 468
Cdd:pfam05483 510 DMTLELKKHQEDIINCKKQE--ERMLKQIENLEEKEMnlrdeLESVREEFIQKGD 562
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
192-422 9.06e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 42.45  E-value: 9.06e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243057505 192 KKKANQLSSRSKARTEWKLEQSMREETLLKvQLTQLKESFQQVQLERDEYS---EHLKGERARWQQRMRKMSQEIctlkk 268
Cdd:COG4717    52 EKEADELFKPQGRKPELNLKELKELEEELK-EAEEKEEEYAELQEELEELEeelEELEAELEELREELEKLEKLL----- 125

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243057505 269 EKQQDMRRVEELERSLSKLKNQMAEPLPPEPPAVPSEVELQHLRKELERVAGELQAQVkknQRISLLNQRQEERIQEQEE 348
Cdd:COG4717   126 QLLPLYQELEALEAELAELPERLEELEERLEELRELEEELEELEAELAELQEELEELL---EQLSLATEEELQDLAEELE 202

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1243057505 349 RLRKQEERIQEQHKSLQQLAKpqsvfeepnnenknalQLEQQVKELQEKLGEEHLEAASQQNQQLTAQLSLMAL 422
Cdd:COG4717   203 ELQQRLAELEEELEEAQEELE----------------ELEEELEQLENELEAAALEERLKEARLLLLIAAALLA 260
PRK11281 PRK11281
mechanosensitive channel MscK;
216-416 9.34e-04

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 42.59  E-value: 9.34e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243057505  216 EETLLKVQLTQLKESFQQVQLERDEySEHLKGERARWQQRMRKMSQEICTLKKEKQQDMRR------VEELERSLSKLKN 289
Cdd:PRK11281    57 EDKLVQQDLEQTLALLDKIDRQKEE-TEQLKQQLAQAPAKLRQAQAELEALKDDNDEETREtlstlsLRQLESRLAQTLD 135

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243057505  290 QMAEPLPPEPPAVPSEVELQhlrKELERVAGELQAQVKKNQRISLLNQRQEERIQEQEERLRKQ--------EERIQEQH 361
Cdd:PRK11281   136 QLQNAQNDLAEYNSQLVSLQ---TQPERAQAALYANSQRLQQIRNLLKGGKVGGKALRPSQRVLlqaeqallNAQNDLQR 212

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1243057505  362 KSLQQLAKPQSVFEEPNNE-NKNALQLEQQVKELQEKLGEEHLEAASQQNQQLTAQ 416
Cdd:PRK11281   213 KSLEGNTQLQDLLQKQRDYlTARIQRLEHQLQLLQEAINSKRLTLSEKTVQEAQSQ 268
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
169-404 1.92e-03

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 41.20  E-value: 1.92e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243057505 169 RLQHSLQRKGELESVLSNVMATQKKKANQLSSRSKARTEWKLEQSMREETLLKvqLTQLKESFQQVQLERDEYSEHLKGE 248
Cdd:PRK03918  180 RLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKE--LEELKEEIEELEKELESLEGSKRKL 257

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243057505 249 RARWQQRMRKMsqeictlkKEKQQDMRRVEELERSLSKLKNQMAEPLPPEPPAVPSEVELQHLRKELERVAGELQAQVKK 328
Cdd:PRK03918  258 EEKIRELEERI--------EELKKEIEELEEKVKELKELKEKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEER 329

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1243057505 329 NQRISllnqrqeeriqeqeerlrKQEERIQEQHKSLQQLAKPQSVFEEPNNENKNALQLEQQVKELQEKLGEEHLE 404
Cdd:PRK03918  330 IKELE------------------EKEERLEELKKKLKELEKRLEELEERHELYEEAKAKKEELERLKKRLTGLTPE 387
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 174-416 3.90e-03

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 40.49  E-value: 3.90e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243057505 174 LQRKGELESVLSNVMATQKKKANQLSSRSKARTEWKLEQSMREETLLKVQLTQLKESFQQVQLERDEYSEHLKGERARWQ 253
Cdd:pfam17380 312 VERRRKLEEAEKARQAEMDRQAAIYAEQERMAMERERELERIRQEERKRELERIRQEEIAMEISRMRELERLQMERQQKN 391

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243057505 254 QRMRKMSQEICTLKKEKQQDMRRVEELERSLSKLKNQMAEPLPPEPPAVPSEVElqhlrKELERVAGELQAQVKKNQRIs 333
Cdd:pfam17380 392 ERVRQELEAARKVKILEEERQRKIQQQKVEMEQIRAEQEEARQREVRRLEEERA-----REMERVRLEEQERQQQVERL- 465

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243057505 334 llnqrqeerIQEQEERLRKQEERIQEQHKSLQQLAKPQSVFEEPNNENKNALQLEQQVKELQEKLGEEHLEAASQQNQQL 413
Cdd:pfam17380 466 ---------RQQEEERKRKKLELEKEKRDRKRAEEQRRKILEKELEERKQAMIEEERKRKLLEKEMEERQKAIYEEERRR 536


                  ...
gi 1243057505 414 TAQ 416
Cdd:pfam17380 537 EAE 539
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 245-418 6.06e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 39.36  E-value: 6.06e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243057505 245 LKGERARWQQRMRKMSQEICTLKKEKQQDMRRVEELERSLSKLKNQMAEPLPPEPPA----VPSEVELQHLRKELERVAG 320
Cdd:COG4942    25 AEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALeaelAELEKEIAELRAELEAQKE 104

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243057505 321 ELQAQVKKNQRIS-------LLNQRQEERIQEQEERL-------RKQEERIQEQHKSLQQLAKPQsvfeepnneNKNALQ 386
Cdd:COG4942   105 ELAELLRALYRLGrqpplalLLSPEDFLDAVRRLQYLkylaparREQAEELRADLAELAALRAEL---------EAERAE 175

                         170       180       190
                  ....*....|....*....|....*....|..
gi 1243057505 387 LEQQVKELQEKLGEehLEAASQQNQQLTAQLS 418
Cdd:COG4942   176 LEALLAELEEERAA--LEALKAERQKLLARLE 205
PTZ00121 PTZ00121
MAEBL; Provisional
 160-381 9.07e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 39.35  E-value: 9.07e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243057505  160 EEKSKDLAVRLQHSLQR--KGELESVLSNVMATQKKKANQL----SSRSKARTEWKLEQSMREETLLKVQLTQLKESFQQ 233
Cdd:PTZ00121  1572 AEEDKNMALRKAEEAKKaeEARIEEVMKLYEEEKKMKAEEAkkaeEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEE 1651

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243057505  234 V------------QLERDEYSEHLKGERARWQQRMRKMSQEictLKKEKQQDMRRVEELERSLSKLKNQMAEPLPPEPPA 301
Cdd:PTZ00121  1652 LkkaeeenkikaaEEAKKAEEDKKKAEEAKKAEEDEKKAAE---ALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEEN 1728

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243057505  302 VPSEVELQHLRKELERVAGELQ---------AQVKKNQRISLLNQRQEERIQEQEERLRKQEERIQEQHKSLQQLAKPQS 372
Cdd:PTZ00121  1729 KIKAEEAKKEAEEDKKKAEEAKkdeeekkkiAHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRMEVDKKIKDIFDNFA 1808


                   ....*....
gi 1243057505  373 VFEEPNNEN 381
Cdd:PTZ00121  1809 NIIEGGKEG 1817
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 161-419 9.45e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 38.59  E-value: 9.45e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243057505 161 EKSKDLAVRLQHSLQRKGELESVLSNVMATQKKKANQLSSRSK--ARTEWKLEQSMREETLLKVQLTQLKESFQQVQLER 238
Cdd:COG4942    20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERriAALARRIRALEQELAALEAELAELEKEIAELRAEL 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243057505 239 DEYSEHLKgERARWQQRMRKMSQEICTLKKEKQQDMRRVEELERSLSK-LKNQMAeplppeppavpsevELQHLRKELER 317
Cdd:COG4942   100 EAQKEELA-ELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPaRREQAE--------------ELRADLAELAA 164

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243057505 318 VAGELQAQVKKNQRIsllnqrqeerIQEQEERLRKQEERIQEQHKSLQQLAKPQSVFEEPNNE-NKNALQLEQQVKELQE 396
Cdd:COG4942   165 LRAELEAERAELEAL----------LAELEEERAALEALKAERQKLLARLEKELAELAAELAElQQEAEELEALIARLEA 234

                         250       260
                  ....*....|....*....|...
gi 1243057505 397 KLGEEHLEAASQQNQQLTAQLSL 419
Cdd:COG4942   235 EAAAAAERTPAAGFAALKGKLPW 257
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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