|
Name |
Accession |
Description |
Interval |
E-value |
| ORC4_C |
pfam14629 |
Origin recognition complex (ORC) subunit 4 C-terminus; This entry represents the C-terminus of ... |
226-413 |
4.53e-57 |
|
Origin recognition complex (ORC) subunit 4 C-terminus; This entry represents the C-terminus of origin recognition complex subunit 4.
Pssm-ID: 464223 Cd Length: 212 Bit Score: 187.16 E-value: 4.53e-57
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 40018564 226 KIFKEQLSLPAEF----PDKIFAEKWNENAHCLSEDSTVLEVLQKHFNVNKNLQSLHMLLMLALNRVTVTHPFMTSADLM 301
Cdd:pfam14629 1 EICKSLLSLPSDEssseGDKKFLEQWNASIEELLEDSTVQDILKRLYYTTKSVRSLLNSLILPVSKLSPDSPLLTAESLL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 40018564 302 EAQHLCSLDAKASIVHGLSVLEICLIIAMKHLNDIYEEEPFNFQMVYNEFQKFIQRK-------------AHSVYNFEKP 368
Cdd:pfam14629 81 SALSSQSPDSKLSLLRSLSVLELCLLIAAARLSEIYDTDTFNFEMVYDEYKKLAKRSkvspssatsqssaASGIRVWGRP 160
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 40018564 369 VVMKAFEHLQQLELIKPMERTSVNS-------QREYQLVKLLLDNTQIMNAL 413
Cdd:pfam14629 161 VALKAWEHLLSLELLVPVGAVSTGGassgsggGKEFRMVRLDITLEEIREAV 212
|
|
| CDC6 |
COG1474 |
Cdc6-related protein, AAA superfamily ATPase [Replication, recombination and repair]; |
41-224 |
4.12e-18 |
|
Cdc6-related protein, AAA superfamily ATPase [Replication, recombination and repair];
Pssm-ID: 441083 [Multi-domain] Cd Length: 389 Bit Score: 85.67 E-value: 4.12e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 40018564 41 QYKHLIELLkRTAIYGES-NSLLIVGPRGSGKTTLLNHALKELMQIGDMSE-NVLQVHLNGLLQTNDKIALKEITRQLNL 118
Cdd:COG1474 34 EIEELASAL-RPALRGERpSNVLIYGPTGTGKTAVAKYVLEELEEEAEERGvDVRVVYVNCRQASTRYRVLSRILEELGS 112
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 40018564 119 ENVVGDKvfG-SFAENLSFLLEALQKGNRtsscPVIFILDEFDLFAHQKNQTLLYNLFDISQS-AQTPIAVIGLTCRLDI 196
Cdd:COG1474 113 GEDIPST--GlSTDELFDRLYEALDERDG----VLVVVLDEIDYLVDDEGDDLLYQLLRANEElEGARVGVIGISNDLEF 186
|
170 180
....*....|....*....|....*...
gi 40018564 197 LELLEKRVKSRFSHRQIHlmnsfdFPQY 224
Cdd:COG1474 187 LENLDPRVKSSLGEEEIV------FPPY 208
|
|
| TIGR02928 |
TIGR02928 |
orc1/cdc6 family replication initiation protein; Members of this protein family are found ... |
56-224 |
2.28e-12 |
|
orc1/cdc6 family replication initiation protein; Members of this protein family are found exclusively in the archaea. This set of DNA binding proteins shows homology to the origin recognition complex subunit 1/cell division control protein 6 family in eukaryotes. Several members may be found in genome and interact with each other. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 274354 [Multi-domain] Cd Length: 365 Bit Score: 68.04 E-value: 2.28e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 40018564 56 GESNSLLIVGPRGSGKTTLLNHALKELMQI-GDMSENVLQVHLNGLLQTNDKIALKEITRQLNlenVVGDKV--FG-SFA 131
Cdd:TIGR02928 38 SRPSNVFIYGKTGTGKTAVTKYVMKELEEAaEDRDVRVVTVYVNCQILDTLYQVLVELANQLR---GSGEEVptTGlSTS 114
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 40018564 132 ENLSFLLEALQKGNRTsscpVIFILDEFDLFAhQKNQTLLYNLFDISQSAQT---PIAVIGLTCRLDILELLEKRVKSRF 208
Cdd:TIGR02928 115 EVFRRLYKELNERGDS----LIIVLDEIDYLV-GDDDDLLYQLSRARSNGDLdnaKVGVIGISNDLKFRENLDPRVKSSL 189
|
170
....*....|....*.
gi 40018564 209 SHRQIHlmnsfdFPQY 224
Cdd:TIGR02928 190 CEEEII------FPPY 199
|
|
| cdc6 |
PRK00411 |
ORC1-type DNA replication protein; |
46-224 |
3.34e-11 |
|
ORC1-type DNA replication protein;
Pssm-ID: 234751 [Multi-domain] Cd Length: 394 Bit Score: 64.48 E-value: 3.34e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 40018564 46 IELLK---RTAIYGESNS-LLIVGPRGSGKTTLLNHALKELMQIgdmSENVLQVHLNGLLQTNDKIALKEITRQLNLENV 121
Cdd:PRK00411 39 IEELAfalRPALRGSRPLnVLIYGPPGTGKTTTVKKVFEELEEI---AVKVVYVYINCQIDRTRYAIFSEIARQLFGHPP 115
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 40018564 122 --VG---DKVFGSFAEnlsflleALQKGNRTsscpVIFILDEFDLFAHQKNQTLLYNLFDISQSAQ-TPIAVIGLTCRLD 195
Cdd:PRK00411 116 psSGlsfDELFDKIAE-------YLDERDRV----LIVALDDINYLFEKEGNDVLYSLLRAHEEYPgARIGVIGISSDLT 184
|
170 180
....*....|....*....|....*....
gi 40018564 196 ILELLEKRVKSRFSHRQIHlmnsfdFPQY 224
Cdd:PRK00411 185 FLYILDPRVKSVFRPEEIY------FPPY 207
|
|
| AAA |
cd00009 |
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily ... |
44-211 |
4.19e-10 |
|
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, RecA-like, VirD4-like, PilT-like, and SF1/2 helicases. Members of the AAA+ ATPases function as molecular chaperons, ATPase subunits of proteases, helicases, or nucleic-acid stimulated ATPases. The AAA+ proteins contain several distinct features in addition to the conserved alpha-beta-alpha core domain structure and the Walker A and B motifs of the P-loop NTPases.
Pssm-ID: 99707 [Multi-domain] Cd Length: 151 Bit Score: 57.93 E-value: 4.19e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 40018564 44 HLIELLKRTAIYGESNSLLIVGPRGSGKTTLLNHALKELmqiGDMSENVLQVHLNGLlqtndkialkeitrqlnLENVVG 123
Cdd:cd00009 5 EAIEALREALELPPPKNLLLYGPPGTGKTTLARAIANEL---FRPGAPFLYLNASDL-----------------LEGLVV 64
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 40018564 124 DKVFGSFAENLSFLLEALQKgnrtsscPVIFILDEFDLFAHQKNQTLLYNL--FDISQSAQTPIAVIGLTCRLDILELLE 201
Cdd:cd00009 65 AELFGHFLVRLLFELAEKAK-------PGVLFIDEIDSLSRGAQNALLRVLetLNDLRIDRENVRVIGATNRPLLGDLDR 137
|
170
....*....|
gi 40018564 202 KRvKSRFSHR 211
Cdd:cd00009 138 AL-YDRLDIR 146
|
|
| AAA_16 |
pfam13191 |
AAA ATPase domain; This family of domains contain a P-loop motif that is characteriztic of the ... |
34-188 |
8.97e-08 |
|
AAA ATPase domain; This family of domains contain a P-loop motif that is characteriztic of the AAA superfamily.
Pssm-ID: 433025 [Multi-domain] Cd Length: 167 Bit Score: 51.74 E-value: 8.97e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 40018564 34 NLFGVQVQYKHLIELLKRTAIyGESNSLLIVGPRGSGKTTLLNHALKelmQIGDMSENVLQ---VHLNGLLQTNDKIALK 110
Cdd:pfam13191 1 RLVGREEELEQLLDALDRVRS-GRPPSVLLTGEAGTGKTTLLRELLR---ALERDGGYFLRgkcDENLPYSPLLEALTRE 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 40018564 111 EITRQLNLENVV----------------GDKVFGSFAENLSFLLEALQKGNRTSSCPVIFILDEFDLFAHQkNQTLLYNL 174
Cdd:pfam13191 77 GLLRQLLDELESslleawraallealapVPELPGDLAERLLDLLLRLLDLLARGERPLVLVLDDLQWADEA-SLQLLAAL 155
|
170
....*....|....
gi 40018564 175 FDISQsaQTPIAVI 188
Cdd:pfam13191 156 LRLLE--SLPLLVV 167
|
|
| AAA |
smart00382 |
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ... |
59-215 |
2.15e-07 |
|
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.
Pssm-ID: 214640 [Multi-domain] Cd Length: 148 Bit Score: 50.06 E-value: 2.15e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 40018564 59 NSLLIVGPRGSGKTTLLNHALKElmqigdmsenvLQVHLNGLLQTNDKIALKEITRQLNLENVVGDKVFGSFAENLSFLL 138
Cdd:smart00382 3 EVILIVGPPGSGKTTLARALARE-----------LGPPGGGVIYIDGEDILEEVLDQLLLIIVGGKKASGSGELRLRLAL 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 40018564 139 EALQKGNrtsscPVIFILDEFDLFAHQKNQTLL----YNLFDISQSAQTPIAVIGLTcrLDILELLEKRVKSRFSHRQIH 214
Cdd:smart00382 72 ALARKLK-----PDVLILDEITSLLDAEQEALLllleELRLLLLLKSEKNLTVILTT--NDEKDLGPALLRRRFDRRIVL 144
|
.
gi 40018564 215 L 215
Cdd:smart00382 145 L 145
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| ORC4_C |
pfam14629 |
Origin recognition complex (ORC) subunit 4 C-terminus; This entry represents the C-terminus of ... |
226-413 |
4.53e-57 |
|
Origin recognition complex (ORC) subunit 4 C-terminus; This entry represents the C-terminus of origin recognition complex subunit 4.
Pssm-ID: 464223 Cd Length: 212 Bit Score: 187.16 E-value: 4.53e-57
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 40018564 226 KIFKEQLSLPAEF----PDKIFAEKWNENAHCLSEDSTVLEVLQKHFNVNKNLQSLHMLLMLALNRVTVTHPFMTSADLM 301
Cdd:pfam14629 1 EICKSLLSLPSDEssseGDKKFLEQWNASIEELLEDSTVQDILKRLYYTTKSVRSLLNSLILPVSKLSPDSPLLTAESLL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 40018564 302 EAQHLCSLDAKASIVHGLSVLEICLIIAMKHLNDIYEEEPFNFQMVYNEFQKFIQRK-------------AHSVYNFEKP 368
Cdd:pfam14629 81 SALSSQSPDSKLSLLRSLSVLELCLLIAAARLSEIYDTDTFNFEMVYDEYKKLAKRSkvspssatsqssaASGIRVWGRP 160
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 40018564 369 VVMKAFEHLQQLELIKPMERTSVNS-------QREYQLVKLLLDNTQIMNAL 413
Cdd:pfam14629 161 VALKAWEHLLSLELLVPVGAVSTGGassgsggGKEFRMVRLDITLEEIREAV 212
|
|
| CDC6 |
COG1474 |
Cdc6-related protein, AAA superfamily ATPase [Replication, recombination and repair]; |
41-224 |
4.12e-18 |
|
Cdc6-related protein, AAA superfamily ATPase [Replication, recombination and repair];
Pssm-ID: 441083 [Multi-domain] Cd Length: 389 Bit Score: 85.67 E-value: 4.12e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 40018564 41 QYKHLIELLkRTAIYGES-NSLLIVGPRGSGKTTLLNHALKELMQIGDMSE-NVLQVHLNGLLQTNDKIALKEITRQLNL 118
Cdd:COG1474 34 EIEELASAL-RPALRGERpSNVLIYGPTGTGKTAVAKYVLEELEEEAEERGvDVRVVYVNCRQASTRYRVLSRILEELGS 112
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 40018564 119 ENVVGDKvfG-SFAENLSFLLEALQKGNRtsscPVIFILDEFDLFAHQKNQTLLYNLFDISQS-AQTPIAVIGLTCRLDI 196
Cdd:COG1474 113 GEDIPST--GlSTDELFDRLYEALDERDG----VLVVVLDEIDYLVDDEGDDLLYQLLRANEElEGARVGVIGISNDLEF 186
|
170 180
....*....|....*....|....*...
gi 40018564 197 LELLEKRVKSRFSHRQIHlmnsfdFPQY 224
Cdd:COG1474 187 LENLDPRVKSSLGEEEIV------FPPY 208
|
|
| TIGR02928 |
TIGR02928 |
orc1/cdc6 family replication initiation protein; Members of this protein family are found ... |
56-224 |
2.28e-12 |
|
orc1/cdc6 family replication initiation protein; Members of this protein family are found exclusively in the archaea. This set of DNA binding proteins shows homology to the origin recognition complex subunit 1/cell division control protein 6 family in eukaryotes. Several members may be found in genome and interact with each other. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 274354 [Multi-domain] Cd Length: 365 Bit Score: 68.04 E-value: 2.28e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 40018564 56 GESNSLLIVGPRGSGKTTLLNHALKELMQI-GDMSENVLQVHLNGLLQTNDKIALKEITRQLNlenVVGDKV--FG-SFA 131
Cdd:TIGR02928 38 SRPSNVFIYGKTGTGKTAVTKYVMKELEEAaEDRDVRVVTVYVNCQILDTLYQVLVELANQLR---GSGEEVptTGlSTS 114
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 40018564 132 ENLSFLLEALQKGNRTsscpVIFILDEFDLFAhQKNQTLLYNLFDISQSAQT---PIAVIGLTCRLDILELLEKRVKSRF 208
Cdd:TIGR02928 115 EVFRRLYKELNERGDS----LIIVLDEIDYLV-GDDDDLLYQLSRARSNGDLdnaKVGVIGISNDLKFRENLDPRVKSSL 189
|
170
....*....|....*.
gi 40018564 209 SHRQIHlmnsfdFPQY 224
Cdd:TIGR02928 190 CEEEII------FPPY 199
|
|
| cdc6 |
PRK00411 |
ORC1-type DNA replication protein; |
46-224 |
3.34e-11 |
|
ORC1-type DNA replication protein;
Pssm-ID: 234751 [Multi-domain] Cd Length: 394 Bit Score: 64.48 E-value: 3.34e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 40018564 46 IELLK---RTAIYGESNS-LLIVGPRGSGKTTLLNHALKELMQIgdmSENVLQVHLNGLLQTNDKIALKEITRQLNLENV 121
Cdd:PRK00411 39 IEELAfalRPALRGSRPLnVLIYGPPGTGKTTTVKKVFEELEEI---AVKVVYVYINCQIDRTRYAIFSEIARQLFGHPP 115
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 40018564 122 --VG---DKVFGSFAEnlsflleALQKGNRTsscpVIFILDEFDLFAHQKNQTLLYNLFDISQSAQ-TPIAVIGLTCRLD 195
Cdd:PRK00411 116 psSGlsfDELFDKIAE-------YLDERDRV----LIVALDDINYLFEKEGNDVLYSLLRAHEEYPgARIGVIGISSDLT 184
|
170 180
....*....|....*....|....*....
gi 40018564 196 ILELLEKRVKSRFSHRQIHlmnsfdFPQY 224
Cdd:PRK00411 185 FLYILDPRVKSVFRPEEIY------FPPY 207
|
|
| AAA |
cd00009 |
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily ... |
44-211 |
4.19e-10 |
|
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, RecA-like, VirD4-like, PilT-like, and SF1/2 helicases. Members of the AAA+ ATPases function as molecular chaperons, ATPase subunits of proteases, helicases, or nucleic-acid stimulated ATPases. The AAA+ proteins contain several distinct features in addition to the conserved alpha-beta-alpha core domain structure and the Walker A and B motifs of the P-loop NTPases.
Pssm-ID: 99707 [Multi-domain] Cd Length: 151 Bit Score: 57.93 E-value: 4.19e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 40018564 44 HLIELLKRTAIYGESNSLLIVGPRGSGKTTLLNHALKELmqiGDMSENVLQVHLNGLlqtndkialkeitrqlnLENVVG 123
Cdd:cd00009 5 EAIEALREALELPPPKNLLLYGPPGTGKTTLARAIANEL---FRPGAPFLYLNASDL-----------------LEGLVV 64
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 40018564 124 DKVFGSFAENLSFLLEALQKgnrtsscPVIFILDEFDLFAHQKNQTLLYNL--FDISQSAQTPIAVIGLTCRLDILELLE 201
Cdd:cd00009 65 AELFGHFLVRLLFELAEKAK-------PGVLFIDEIDSLSRGAQNALLRVLetLNDLRIDRENVRVIGATNRPLLGDLDR 137
|
170
....*....|
gi 40018564 202 KRvKSRFSHR 211
Cdd:cd00009 138 AL-YDRLDIR 146
|
|
| NACHT |
COG5635 |
Predicted NTPase, NACHT family domain [Signal transduction mechanisms]; |
57-285 |
3.17e-09 |
|
Predicted NTPase, NACHT family domain [Signal transduction mechanisms];
Pssm-ID: 444362 [Multi-domain] Cd Length: 935 Bit Score: 59.05 E-value: 3.17e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 40018564 57 ESNSLLIVGPRGSGKTTLLNHALKELMQIGDMSENVLQVHLNgllqtndkiaLKEITRQLNLENVVGDKVFGSFAENLSF 136
Cdd:COG5635 179 KKKRLLILGEPGSGKTTLLRYLALELAERYLDAEDPIPILIE----------LRDLAEEASLEDLLAEALEKRGGEPEDA 248
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 40018564 137 LLEALQKGNrtsscpVIFILDEFDLFAHQKNQTLLYNLFDISQSAQTPIAVIgLTCRLDILEllekrvKSRFSHRQIHLM 216
Cdd:COG5635 249 LERLLRNGR------LLLLLDGLDEVPDEADRDEVLNQLRRFLERYPKARVI-ITSRPEGYD------SSELEGFEVLEL 315
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 40018564 217 NSFDFPQylkIFKeqlslpaefpdkiFAEKWNENAHCLSEDstvlevLQKHFNVNKNLQSL----HMLLMLAL 285
Cdd:COG5635 316 APLSDEQ---IEE-------------FLKKWFEATERKAER------LLEALEENPELRELarnpLLLTLLAL 366
|
|
| AAA_16 |
pfam13191 |
AAA ATPase domain; This family of domains contain a P-loop motif that is characteriztic of the ... |
34-188 |
8.97e-08 |
|
AAA ATPase domain; This family of domains contain a P-loop motif that is characteriztic of the AAA superfamily.
Pssm-ID: 433025 [Multi-domain] Cd Length: 167 Bit Score: 51.74 E-value: 8.97e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 40018564 34 NLFGVQVQYKHLIELLKRTAIyGESNSLLIVGPRGSGKTTLLNHALKelmQIGDMSENVLQ---VHLNGLLQTNDKIALK 110
Cdd:pfam13191 1 RLVGREEELEQLLDALDRVRS-GRPPSVLLTGEAGTGKTTLLRELLR---ALERDGGYFLRgkcDENLPYSPLLEALTRE 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 40018564 111 EITRQLNLENVV----------------GDKVFGSFAENLSFLLEALQKGNRTSSCPVIFILDEFDLFAHQkNQTLLYNL 174
Cdd:pfam13191 77 GLLRQLLDELESslleawraallealapVPELPGDLAERLLDLLLRLLDLLARGERPLVLVLDDLQWADEA-SLQLLAAL 155
|
170
....*....|....
gi 40018564 175 FDISQsaQTPIAVI 188
Cdd:pfam13191 156 LRLLE--SLPLLVV 167
|
|
| AAA |
smart00382 |
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ... |
59-215 |
2.15e-07 |
|
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.
Pssm-ID: 214640 [Multi-domain] Cd Length: 148 Bit Score: 50.06 E-value: 2.15e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 40018564 59 NSLLIVGPRGSGKTTLLNHALKElmqigdmsenvLQVHLNGLLQTNDKIALKEITRQLNLENVVGDKVFGSFAENLSFLL 138
Cdd:smart00382 3 EVILIVGPPGSGKTTLARALARE-----------LGPPGGGVIYIDGEDILEEVLDQLLLIIVGGKKASGSGELRLRLAL 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 40018564 139 EALQKGNrtsscPVIFILDEFDLFAHQKNQTLL----YNLFDISQSAQTPIAVIGLTcrLDILELLEKRVKSRFSHRQIH 214
Cdd:smart00382 72 ALARKLK-----PDVLILDEITSLLDAEQEALLllleELRLLLLLKSEKNLTVILTT--NDEKDLGPALLRRRFDRRIVL 144
|
.
gi 40018564 215 L 215
Cdd:smart00382 145 L 145
|
|
| COG1672 |
COG1672 |
Predicted ATPase, archaeal AAA+ ATPase superfamily [General function prediction only]; |
46-159 |
7.76e-06 |
|
Predicted ATPase, archaeal AAA+ ATPase superfamily [General function prediction only];
Pssm-ID: 441278 [Multi-domain] Cd Length: 324 Bit Score: 47.60 E-value: 7.76e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 40018564 46 IELLKRtAIYGESNSLLIV-GPRGSGKTTLLNHALKElmqigdmsENVlqVHLNgLLQTNDKIALKEITRQLN--LENVV 122
Cdd:COG1672 9 LEELEK-LYESDGGELVVVyGRRRVGKTSLIKEFLKE--------KPA--IYFD-AREESERESLRDFSEALAeaLGDPL 76
|
90 100 110
....*....|....*....|....*....|....*..
gi 40018564 123 GDKVFGSFAENLSFLLEALQKGnrtsscPVIFILDEF 159
Cdd:COG1672 77 SKKEFESWEEAFEYLAELAEGK------RLVIVIDEF 107
|
|
| AAA_22 |
pfam13401 |
AAA domain; |
60-188 |
1.29e-05 |
|
AAA domain;
Pssm-ID: 379165 [Multi-domain] Cd Length: 129 Bit Score: 44.64 E-value: 1.29e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 40018564 60 SLLIVGPRGSGKTTLLNHALKELMQigdmsENVLQVHLNGLLQTNDKIALKEITRQLNLEnvvgdkvfGSFAENLSFLLE 139
Cdd:pfam13401 7 ILVLTGESGTGKTTLLRRLLEQLPE-----VRDSVVFVDLPSGTSPKDLLRALLRALGLP--------LSGRLSKEELLA 73
|
90 100 110 120
....*....|....*....|....*....|....*....|....*....
gi 40018564 140 ALQKGNRTSSCPVIFILDEFDLFahqkNQTLLYNLFDISQSAQTPIAVI 188
Cdd:pfam13401 74 ALQQLLLALAVAVVLIIDEAQHL----SLEALEELRDLLNLSSKLLQLI 118
|
|
| AAA |
pfam00004 |
ATPase family associated with various cellular activities (AAA); AAA family proteins often ... |
61-212 |
1.50e-05 |
|
ATPase family associated with various cellular activities (AAA); AAA family proteins often perform chaperone-like functions that assist in the assembly, operation, or disassembly of protein complexes.
Pssm-ID: 459627 [Multi-domain] Cd Length: 130 Bit Score: 44.12 E-value: 1.50e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 40018564 61 LLIVGPRGSGKTTLLnHALkelmqIGDMSENVLQVHLNGLLqtndkialkeitrqlnlenvvgDKVFGSFAENLSFLLEA 140
Cdd:pfam00004 1 LLLYGPPGTGKTTLA-KAV-----AKELGAPFIEISGSELV----------------------SKYVGESEKRLRELFEA 52
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 40018564 141 LQKGNrtsscPVIFILDEFDLFA----------HQKNQTLLYNLFDISQSAQTPIAVIGLTCRLDileLLEKRVKSRFSH 210
Cdd:pfam00004 53 AKKLA-----PCVIFIDEIDALAgsrgsggdseSRRVVNQLLTELDGFTSSNSKVIVIAATNRPD---KLDPALLGRFDR 124
|
..
gi 40018564 211 RQ 212
Cdd:pfam00004 125 II 126
|
|
| ATPase_2 |
pfam01637 |
ATPase domain predominantly from Archaea; This family contain a conserved P-loop motif that is ... |
61-249 |
3.66e-04 |
|
ATPase domain predominantly from Archaea; This family contain a conserved P-loop motif that is involved in binding ATP. There are eukaryote members as well as archaeal members in this family.
Pssm-ID: 376582 [Multi-domain] Cd Length: 222 Bit Score: 41.54 E-value: 3.66e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 40018564 61 LLIVGPRGSGKTTLLNHALKELMQIGDMSENVLQVHLNGLLQTNDKIALKEitrqlnLENVVGDKVFGSFAE-------N 133
Cdd:pfam01637 23 YVIYGPEGCGKTALLRESIENLLDLGYYVIYYDPLRRYFISKLDRFEEVRR------LAEALGIAVPKAELEesklaflA 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 40018564 134 LSFLLEALqkgNRTSSCPVIFILDEFDLFAHQKNQTL---LYNLFDISQSAQTPIAVIGLTC------RLDILELLEKRv 204
Cdd:pfam01637 97 IELLLEAL---KRRGKKIAIIIDEVQQAIGLNGAELLvkeLLNLIEYLTKEYHLCHVICLSSeglfieLVYYKSPLIGR- 172
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 40018564 205 ksrfsHRQIHLMnSFDFPQYLKIFKEQLSLPAEFPDKIFAEKWNE 249
Cdd:pfam01637 173 -----HRWALVD-PLDKETAWNFLKEGFKELYELSKEDFEEIWRY 211
|
|
| COG1373 |
COG1373 |
Predicted ATPase, AAA+ superfamily [General function prediction only]; |
42-158 |
4.54e-04 |
|
Predicted ATPase, AAA+ superfamily [General function prediction only];
Pssm-ID: 440984 [Multi-domain] Cd Length: 405 Bit Score: 42.24 E-value: 4.54e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 40018564 42 YKHLIELLKRTAIygesnsLLIVGPRGSGKTTLLNHALKELMQIgdmsenvlqvhlngllqtndkialkeitRQLNLENv 121
Cdd:COG1373 10 LDKLLKLLDNRKA------VVITGPRQVGKTTLLKQLAKELENI----------------------------LYINLDD- 54
|
90 100 110
....*....|....*....|....*....|....*..
gi 40018564 122 vgDKVFGSFAENLSFLLEALQKGNRTsscPVIFILDE 158
Cdd:COG1373 55 --PRLRALAEEDPDDLLEALKELYPG---KTYLFLDE 86
|
|
| AAA_19 |
pfam13245 |
AAA domain; |
57-99 |
5.79e-04 |
|
AAA domain;
Pssm-ID: 433059 [Multi-domain] Cd Length: 136 Bit Score: 39.89 E-value: 5.79e-04
10 20 30 40
....*....|....*....|....*....|....*....|...
gi 40018564 57 ESNSLLIVGPrGSGKTTLLNHALKELMQIGDMSENVLQVHLNG 99
Cdd:pfam13245 11 SKVVLLTGGP-GTGKTTTIRHIVALLVALGGVSFPILLAAPTG 52
|
|
| PTZ00112 |
PTZ00112 |
origin recognition complex 1 protein; Provisional |
56-232 |
8.83e-04 |
|
origin recognition complex 1 protein; Provisional
Pssm-ID: 240274 [Multi-domain] Cd Length: 1164 Bit Score: 41.90 E-value: 8.83e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 40018564 56 GESNSLLIVGPRGSGKTT-------LLNHALKELMQigdMSENVLQVhlNGLLQTNDKIALKEITRQLNleNVVGDKVFG 128
Cdd:PTZ00112 779 GSNQILYISGMPGTGKTAtvysviqLLQHKTKQKLL---PSFNVFEI--NGMNVVHPNAAYQVLYKQLF--NKKPPNALN 851
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 40018564 129 SFaENLSFLLEALQKGNRTSScpvIFILDEFDlFAHQKNQTLLYNLFDISQSAQTPIAVIGLTCRLDILELLEKRVKSRF 208
Cdd:PTZ00112 852 SF-KILDRLFNQNKKDNRNVS---ILIIDEID-YLITKTQKVLFTLFDWPTKINSKLVLIAISNTMDLPERLIPRCRSRL 926
|
170 180
....*....|....*....|....
gi 40018564 209 SHRQIhLMNSFDFPQYLKIFKEQL 232
Cdd:PTZ00112 927 AFGRL-VFSPYKGDEIEKIIKERL 949
|
|
| AAA_14 |
pfam13173 |
AAA domain; This family of domains contain a P-loop motif that is characteriztic of the AAA ... |
61-158 |
1.51e-03 |
|
AAA domain; This family of domains contain a P-loop motif that is characteriztic of the AAA superfamily.
Pssm-ID: 463799 [Multi-domain] Cd Length: 128 Bit Score: 38.34 E-value: 1.51e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 40018564 61 LLIVGPRGSGKTTLLNHALKELMQigdmSENVLQVHLngllqtnDKIALKEItrqlnlenvvgdkvfgSFAENLSFLLEA 140
Cdd:pfam13173 5 LVITGPRQVGKTTLLLQLIKELLP----PENILYINL-------DDPRLLKL----------------ADFELLELFLEL 57
|
90
....*....|....*...
gi 40018564 141 LQKGNRtsscpvIFILDE 158
Cdd:pfam13173 58 LYPGKT------YLFLDE 69
|
|
| VI_IcmF |
TIGR03348 |
type VI secretion protein IcmF; Members of this protein family are IcmF homologs and tend to ... |
38-78 |
2.56e-03 |
|
type VI secretion protein IcmF; Members of this protein family are IcmF homologs and tend to be associated with type VI secretion systems. [Cellular processes, Pathogenesis]
Pssm-ID: 274531 [Multi-domain] Cd Length: 1169 Bit Score: 40.40 E-value: 2.56e-03
10 20 30 40
....*....|....*....|....*....|....*....|....*..
gi 40018564 38 VQVQYKHLIELLKRTAIYGEsNSL------LIVGPRGSGKTTLLNHA 78
Cdd:TIGR03348 86 LRARFNEALALLKRSRLGGR-RYLydlpwyLVIGPPGSGKTTLLQNS 131
|
|
| VirB11 |
COG0630 |
Type IV secretory pathway ATPase VirB11/Archaellum biosynthesis ATPase ArlI/FlaI [Cell ... |
60-122 |
2.72e-03 |
|
Type IV secretory pathway ATPase VirB11/Archaellum biosynthesis ATPase ArlI/FlaI [Cell motility, Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 440395 [Multi-domain] Cd Length: 462 Bit Score: 40.06 E-value: 2.72e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 40018564 60 SLLIVGPRGSGKTTLLNhALkeLMqigdmsenvlqvhlngLLQTNDKIALKEITRQLNL--ENVV 122
Cdd:COG0630 292 SVLVAGGTASGKTTLLN-AL--LS----------------FIPPDAKIVTIEDTRELNLphENWI 337
|
|
| DAP3 |
pfam10236 |
Mitochondrial ribosomal death-associated protein 3; This is a family of conserved proteins ... |
45-79 |
4.54e-03 |
|
Mitochondrial ribosomal death-associated protein 3; This is a family of conserved proteins which were originally described as death-associated-protein-3 (DAP-3). The proteins carry a P-loop DNA-binding motif, and induce apoptosis. DAP3 has been shown to be a pro-apoptotic factor in the mitochondrial matrix and to be crucial for mitochondrial biogenesis and so has also been designated as MRP-S29 (mitochondrial ribosomal protein subunit 29).
Pssm-ID: 431160 Cd Length: 310 Bit Score: 38.82 E-value: 4.54e-03
10 20 30
....*....|....*....|....*....|....*
gi 40018564 45 LIELLKRTAIYGESNSLLIVGPRGSGKTTLLNHAL 79
Cdd:pfam10236 10 LIKKLKAADKSKKVVRFVLTGEPGSGKSVLLLQAM 44
|
|
| PulE |
COG2804 |
Type II secretory pathway ATPase GspE/PulE or T4P pilus assembly pathway ATPase PilB [Cell ... |
61-115 |
4.83e-03 |
|
Type II secretory pathway ATPase GspE/PulE or T4P pilus assembly pathway ATPase PilB [Cell motility, Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];
Pssm-ID: 442055 [Multi-domain] Cd Length: 561 Bit Score: 39.02 E-value: 4.83e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 40018564 61 LLIVGPRGSGKTTLLNHALKELMQIGDmseNVLQV------HLNGLLQT--NDKI------ALKEITRQ 115
Cdd:COG2804 316 ILVTGPTGSGKTTTLYAALNELNTPER---NIITVedpveyQLPGINQVqvNPKIgltfasALRSILRQ 381
|
|
| AAA_35 |
pfam14516 |
AAA-like domain; This family of proteins are part of the AAA superfamily. |
63-164 |
4.99e-03 |
|
AAA-like domain; This family of proteins are part of the AAA superfamily.
Pssm-ID: 373105 Cd Length: 331 Bit Score: 38.65 E-value: 4.99e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 40018564 63 IVGPRGSGKTTLLNHALKELMQIGDMSenvlqVHLNglLQTNDKIALK-----------EITRQLNLENVVG---DKVFG 128
Cdd:pfam14516 36 IKAPRQMGKTSLLLRILAYAQQQGYRT-----VYLD--FQLADKAILTdldkflrwfcaNISRQLGLPPKLDdywDEDLG 108
|
90 100 110 120
....*....|....*....|....*....|....*....|....
gi 40018564 129 SfaeNLS-------FLLEALQKgnrtsscPVIFILDEFD-LFAH 164
Cdd:pfam14516 109 S---KVSctiyfedYLLPQIDR-------PLVLALDEVDrLFEY 142
|
|
| T2SSE |
pfam00437 |
Type II/IV secretion system protein; This family contains components of both the Type II ... |
60-115 |
5.19e-03 |
|
Type II/IV secretion system protein; This family contains components of both the Type II protein secretion system (T2SS), including Type 4 pilus (T4P), and Type IV protein secretion system (T4SS) from Gram-negative bacteria. VirB11 ATPase is a subunit of the Agrobacterium tumefaciens transfer DNA (T-DNA) transfer system, a type IV secretion pathway required for delivery of T-DNA and effector proteins to plant cells during infection. The cytoplasmic T2S E ATPase is a Zn-containing protein thought to provide the mechanical force for the secretion process. T2S-E contains Walker A and B motifs, that are essential for secretion and ATPase activity. ATPase PulE and XcpR from Klebsiella oxytoca and Pseudomonas aeruginosa respectively are required for protein secretion via the T2SS. ATPase PilB is required for T4P extension.
Pssm-ID: 425681 [Multi-domain] Cd Length: 269 Bit Score: 38.42 E-value: 5.19e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 40018564 60 SLLIVGPRGSGKTTLLNHALKEL-------MQIGDMSENVL----QVHLN--GLLQTNDkiALKEITRQ 115
Cdd:pfam00437 132 NILVTGPTGSGKTTTLYAALGELntrdeniVTVEDPVEIQLeginQVQLNarAGVTFAD--LLRAILRQ 198
|
|
| LolD |
COG1136 |
ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis]; |
56-76 |
6.44e-03 |
|
ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440751 [Multi-domain] Cd Length: 227 Bit Score: 38.10 E-value: 6.44e-03
|
| |
