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Conserved domains on  [gi|564336829|ref|XP_006232557|]
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zinc finger B-box domain-containing protein 1 isoform X7 [Rattus norvegicus]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Bbox1_ZBBX cd19818
B-box-type 1 zinc finger found in zinc finger B-box domain-containing protein 1 (ZBBX) and ...
 16-58 6.39e-23

B-box-type 1 zinc finger found in zinc finger B-box domain-containing protein 1 (ZBBX) and similar proteins; The family corresponds to a group of uncharacterized zinc finger B-box domain-containing proteins. The B-box motif shows high sequence similarity with B-Box-type 1 zinc finger found in tripartite motif-containing proteins (TRIMs). The type 1 B-box (Bbox1) zinc finger is characterized by a C6H2 zinc-binding consensus motif.


:

Pssm-ID: 380876  Cd Length: 43  Bit Score: 91.66  E-value: 6.39e-23
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|...
gi 564336829  16 VCGQCENKAALLVCLECGEDYCSGCFARMHQKGALKFHRTTLL 58
Cdd:cd19818    1 QCGQCEQKAALLVCLECGEDYCSSCFAKFHQKGALKKHRSIPL 43
PRK08581 super family cl35718
amidase domain-containing protein;
346-587 1.63e-03

amidase domain-containing protein;


The actual alignment was detected with superfamily member PRK08581:

Pssm-ID: 236304 [Multi-domain]  Cd Length: 619  Bit Score: 41.70  E-value: 1.63e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564336829 346 TNSGHHKDELKEEISSQDINTSLECSKQNERSNFEDSKTTKPplLRKVALRRKPVNERYQGPKKFFPADKNER------- 418
Cdd:PRK08581  36 AKTTSHDSKKSNDDETSKDTSSKDTDKADNNNTSNQDNNDKK--FSTIDSSTSDSNNIIDFIYKNLPQTNINQlltknky 113

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564336829 419 ---------LNALPSSSIKGSHSCSEITSTVSEDKLWVPVSSLSGCAGNTDVLKDQQSDENPLPHVQQQK-----TGQKS 484
Cdd:PRK08581 114 ddnyslttlIQNLFNLNSDISDYEQPRNSEKSTNDSNKNSDSSIKNDTDTQSSKQDKADNQKAPSSNNTKpstsnKQPNS 193

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564336829 485 QRPSTANIPVSNSDQKDTSCLLSSYSRSKSADPQFPSRAASEISEieyiDVTEQNELFGGNTVDQQALDTLEKelnilrN 564
Cdd:PRK08581 194 PKPTQPNQSNSQPASDDTANQKSSSKDNQSMSDSALDSILDQYSE----DAKKTQKDYASQSKKDKTETSNTK------N 263

                        250       260
                 ....*....|....*....|...
gi 564336829 565 PADPSEESHSIPSEQFQAFNDNF 587
Cdd:PRK08581 264 PQLPTQDELKHKSKPAQSFENDV 286
 
Name Accession Description Interval E-value
Bbox1_ZBBX cd19818
B-box-type 1 zinc finger found in zinc finger B-box domain-containing protein 1 (ZBBX) and ...
 16-58 6.39e-23

B-box-type 1 zinc finger found in zinc finger B-box domain-containing protein 1 (ZBBX) and similar proteins; The family corresponds to a group of uncharacterized zinc finger B-box domain-containing proteins. The B-box motif shows high sequence similarity with B-Box-type 1 zinc finger found in tripartite motif-containing proteins (TRIMs). The type 1 B-box (Bbox1) zinc finger is characterized by a C6H2 zinc-binding consensus motif.


Pssm-ID: 380876  Cd Length: 43  Bit Score: 91.66  E-value: 6.39e-23
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|...
gi 564336829  16 VCGQCENKAALLVCLECGEDYCSGCFARMHQKGALKFHRTTLL 58
Cdd:cd19818    1 QCGQCEQKAALLVCLECGEDYCSSCFAKFHQKGALKKHRSIPL 43
BBOX smart00336
B-Box-type zinc finger;
13-58 2.15e-04

B-Box-type zinc finger;


Pssm-ID: 197662 [Multi-domain]  Cd Length: 42  Bit Score: 39.24  E-value: 2.15e-04
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*.
gi 564336829    13 KRKVCGQCENKAALLVCLECGEDYCSGCFARMHQKgalkfHRTTLL 58
Cdd:smart00336   2 RAPKCDSHGDEPAEFFCEECGALLCRTCDEAEHRG-----HTVVLL 42
PRK08581 PRK08581
amidase domain-containing protein;
346-587 1.63e-03

amidase domain-containing protein;


Pssm-ID: 236304 [Multi-domain]  Cd Length: 619  Bit Score: 41.70  E-value: 1.63e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564336829 346 TNSGHHKDELKEEISSQDINTSLECSKQNERSNFEDSKTTKPplLRKVALRRKPVNERYQGPKKFFPADKNER------- 418
Cdd:PRK08581  36 AKTTSHDSKKSNDDETSKDTSSKDTDKADNNNTSNQDNNDKK--FSTIDSSTSDSNNIIDFIYKNLPQTNINQlltknky 113

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564336829 419 ---------LNALPSSSIKGSHSCSEITSTVSEDKLWVPVSSLSGCAGNTDVLKDQQSDENPLPHVQQQK-----TGQKS 484
Cdd:PRK08581 114 ddnyslttlIQNLFNLNSDISDYEQPRNSEKSTNDSNKNSDSSIKNDTDTQSSKQDKADNQKAPSSNNTKpstsnKQPNS 193

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564336829 485 QRPSTANIPVSNSDQKDTSCLLSSYSRSKSADPQFPSRAASEISEieyiDVTEQNELFGGNTVDQQALDTLEKelnilrN 564
Cdd:PRK08581 194 PKPTQPNQSNSQPASDDTANQKSSSKDNQSMSDSALDSILDQYSE----DAKKTQKDYASQSKKDKTETSNTK------N 263

                        250       260
                 ....*....|....*....|...
gi 564336829 565 PADPSEESHSIPSEQFQAFNDNF 587
Cdd:PRK08581 264 PQLPTQDELKHKSKPAQSFENDV 286
zf-B_box pfam00643
B-box zinc finger;
12-58 1.66e-03

B-box zinc finger;


Pssm-ID: 459886 [Multi-domain]  Cd Length: 42  Bit Score: 36.68  E-value: 1.66e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*..
gi 564336829   12 TKRKVCGQCENKAALLVCLECGEDYCSGCFARMHQKgalkfHRTTLL 58
Cdd:pfam00643   1 SKERLCPEHEEEPLTLYCNDCQELLCEECSVGEHRG-----HTVVPL 42
 
Name Accession Description Interval E-value
Bbox1_ZBBX cd19818
B-box-type 1 zinc finger found in zinc finger B-box domain-containing protein 1 (ZBBX) and ...
 16-58 6.39e-23

B-box-type 1 zinc finger found in zinc finger B-box domain-containing protein 1 (ZBBX) and similar proteins; The family corresponds to a group of uncharacterized zinc finger B-box domain-containing proteins. The B-box motif shows high sequence similarity with B-Box-type 1 zinc finger found in tripartite motif-containing proteins (TRIMs). The type 1 B-box (Bbox1) zinc finger is characterized by a C6H2 zinc-binding consensus motif.


Pssm-ID: 380876  Cd Length: 43  Bit Score: 91.66  E-value: 6.39e-23
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|...
gi 564336829  16 VCGQCENKAALLVCLECGEDYCSGCFARMHQKGALKFHRTTLL 58
Cdd:cd19818    1 QCGQCEQKAALLVCLECGEDYCSSCFAKFHQKGALKKHRSIPL 43
Bbox1 cd19757
B-box-type 1 zinc finger (Bbox1); The B-box-type zinc finger is a short zinc binding domain of ...
 16-58 3.15e-09

B-box-type 1 zinc finger (Bbox1); The B-box-type zinc finger is a short zinc binding domain of around 40 amino acid residues in length. It has been found in transcription factors, ribonucleoproteins and proto-oncoproteins, such as in TRIM (tripartite motif) proteins that consist of an N-terminal RING finger (originally called an A-box), followed by 1-2 B-box domains and a coiled-coil domain (also called RBCC for Ring, B-box, Coiled-Coil). The B-box-type zinc finger often presents in combination with other motifs, like RING zinc finger, NHL motif, coiled-coil or RFP domain, in functionally unrelated proteins, most likely mediating protein-protein interactions. Based on different consensus sequences and the spacing of the 7-8 zinc-binding residues, the B-box-type zinc fingers can be divided into two groups, type 1 (Bbox1: C6H2) and type 2 (Bbox2: CHC3H2). This family corresponds to the type 1 B-box (Bbox1).


Pssm-ID: 380815 [Multi-domain]  Cd Length: 44  Bit Score: 52.88  E-value: 3.15e-09
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....
gi 564336829  16 VCGQCENKAALLVCLECGEDYCSGCFARMHQKG-ALKFHRTTLL 58
Cdd:cd19757    1 LCDECEEREATVYCLECEEFLCDDCSDAIHRRGkLTRSHKLVPL 44
Bbox1_DUF2009 cd20208
B-box-type 1 zinc finger found in DUF2009 domain-containing proteins and similar proteins; ...
 16-56 1.76e-06

B-box-type 1 zinc finger found in DUF2009 domain-containing proteins and similar proteins; This group is composed of uncharacterized proteins containing a zinc finger B-box domain and a DUF2009 domain, and similar zinc finger B-box domain-containing proteins. The B-box motif shows high sequence similarity with B-Box-type 1 zinc finger found in tripartite motif-containing proteins (TRIMs). The type 1 B-box (Bbox1) zinc finger is characterized by a C6H2 zinc-binding consensus motif.


Pssm-ID: 380909 [Multi-domain]  Cd Length: 43  Bit Score: 45.06  E-value: 1.76e-06
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|.
gi 564336829  16 VCGQCENKAALLVCLECGEDYCSGCFARMHQKGALKFHRTT 56
Cdd:cd20208    1 MCIECEDQPAEVRCEECGDEFCEVCFQSQHRKGKRRLHSFR 41
BBOX smart00336
B-Box-type zinc finger;
13-58 2.15e-04

B-Box-type zinc finger;


Pssm-ID: 197662 [Multi-domain]  Cd Length: 42  Bit Score: 39.24  E-value: 2.15e-04
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*.
gi 564336829    13 KRKVCGQCENKAALLVCLECGEDYCSGCFARMHQKgalkfHRTTLL 58
Cdd:smart00336   2 RAPKCDSHGDEPAEFFCEECGALLCRTCDEAEHRG-----HTVVLL 42
PRK08581 PRK08581
amidase domain-containing protein;
346-587 1.63e-03

amidase domain-containing protein;


Pssm-ID: 236304 [Multi-domain]  Cd Length: 619  Bit Score: 41.70  E-value: 1.63e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564336829 346 TNSGHHKDELKEEISSQDINTSLECSKQNERSNFEDSKTTKPplLRKVALRRKPVNERYQGPKKFFPADKNER------- 418
Cdd:PRK08581  36 AKTTSHDSKKSNDDETSKDTSSKDTDKADNNNTSNQDNNDKK--FSTIDSSTSDSNNIIDFIYKNLPQTNINQlltknky 113

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564336829 419 ---------LNALPSSSIKGSHSCSEITSTVSEDKLWVPVSSLSGCAGNTDVLKDQQSDENPLPHVQQQK-----TGQKS 484
Cdd:PRK08581 114 ddnyslttlIQNLFNLNSDISDYEQPRNSEKSTNDSNKNSDSSIKNDTDTQSSKQDKADNQKAPSSNNTKpstsnKQPNS 193

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564336829 485 QRPSTANIPVSNSDQKDTSCLLSSYSRSKSADPQFPSRAASEISEieyiDVTEQNELFGGNTVDQQALDTLEKelnilrN 564
Cdd:PRK08581 194 PKPTQPNQSNSQPASDDTANQKSSSKDNQSMSDSALDSILDQYSE----DAKKTQKDYASQSKKDKTETSNTK------N 263

                        250       260
                 ....*....|....*....|...
gi 564336829 565 PADPSEESHSIPSEQFQAFNDNF 587
Cdd:PRK08581 264 PQLPTQDELKHKSKPAQSFENDV 286
zf-B_box pfam00643
B-box zinc finger;
12-58 1.66e-03

B-box zinc finger;


Pssm-ID: 459886 [Multi-domain]  Cd Length: 42  Bit Score: 36.68  E-value: 1.66e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*..
gi 564336829   12 TKRKVCGQCENKAALLVCLECGEDYCSGCFARMHQKgalkfHRTTLL 58
Cdd:pfam00643   1 SKERLCPEHEEEPLTLYCNDCQELLCEECSVGEHRG-----HTVVPL 42
Bbox1_ANCHR-like cd19817
B-box-type 1 zinc finger found in Abscission/NoCut checkpoint regulator (ANCHR) and similar ...
 17-56 1.69e-03

B-box-type 1 zinc finger found in Abscission/NoCut checkpoint regulator (ANCHR) and similar proteins; ANCHR, also termed MLL partner containing FYVE domain, or zinc finger FYVE domain-containing protein 19, is a key regulator of the abscission step in cytokinesis: part of the cytokinesis checkpoint, a process required to delay abscission to prevent both premature resolution of intercellular chromosome bridges and accumulation of DNA damage. The family also includes zinc finger B-box domain-containing protein 1 (ZBBX), a B-box motif containing protein with unclear biological function. The B-box motif of this family shows high sequence similarity with B-Box-type 1 zinc finger found in tripartite motif-containing proteins (TRIMs). The type 1 B-box (Bbox1) zinc finger is characterized by a C6H2 zinc-binding consensus motif.


Pssm-ID: 380875  Cd Length: 45  Bit Score: 36.51  E-value: 1.69e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|.
gi 564336829  17 CGQCeNKAALLVCLECGED-YCSGCFARMHQKGALKFHRTT 56
Cdd:cd19817    4 CCIC-NEDASLRCHGCDGDlYCKRCFREGHDGFDRRDHRTV 43
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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