DEUBAD domain found in nuclear factor related to kappa-B-binding protein (NFRKB) and similar ...
42-153
4.90e-53
DEUBAD domain found in nuclear factor related to kappa-B-binding protein (NFRKB) and similar proteins; NFRKB, also called DNA-binding protein R kappa-B, or INO80 complex subunit G (INO80G), is a regulatory component of the metazoan INO80 complex involved in chromatin remodeling, transcription regulation, DNA replication and DNA repair. It modulates the deubiquitinase activity of UCHL5 in the INO80 complex. It binds to the DNA consensus sequence 5'-GGGGAATCTCC-3'. The model corresponds to the DEUBAD domain (conserved domain within the UCH regulatory proteins RPN13, NFRKB/INO80G, and ASX) of NFRKB, which binds primarily to the C-terminal ULD domain of UCH-L5.
:
Pssm-ID: 439381 Cd Length: 112 Bit Score: 180.87 E-value: 4.90e-53
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ...
981-1187
6.87e-03
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.
The actual alignment was detected with superfamily member pfam05109:
Pssm-ID: 282904 [Multi-domain] Cd Length: 886 Bit Score: 40.67 E-value: 6.87e-03
DEUBAD domain found in nuclear factor related to kappa-B-binding protein (NFRKB) and similar ...
42-153
4.90e-53
DEUBAD domain found in nuclear factor related to kappa-B-binding protein (NFRKB) and similar proteins; NFRKB, also called DNA-binding protein R kappa-B, or INO80 complex subunit G (INO80G), is a regulatory component of the metazoan INO80 complex involved in chromatin remodeling, transcription regulation, DNA replication and DNA repair. It modulates the deubiquitinase activity of UCHL5 in the INO80 complex. It binds to the DNA consensus sequence 5'-GGGGAATCTCC-3'. The model corresponds to the DEUBAD domain (conserved domain within the UCH regulatory proteins RPN13, NFRKB/INO80G, and ASX) of NFRKB, which binds primarily to the C-terminal ULD domain of UCH-L5.
Pssm-ID: 439381 Cd Length: 112 Bit Score: 180.87 E-value: 4.90e-53
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ...
981-1187
6.87e-03
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.
Pssm-ID: 282904 [Multi-domain] Cd Length: 886 Bit Score: 40.67 E-value: 6.87e-03
DEUBAD domain found in nuclear factor related to kappa-B-binding protein (NFRKB) and similar ...
42-153
4.90e-53
DEUBAD domain found in nuclear factor related to kappa-B-binding protein (NFRKB) and similar proteins; NFRKB, also called DNA-binding protein R kappa-B, or INO80 complex subunit G (INO80G), is a regulatory component of the metazoan INO80 complex involved in chromatin remodeling, transcription regulation, DNA replication and DNA repair. It modulates the deubiquitinase activity of UCHL5 in the INO80 complex. It binds to the DNA consensus sequence 5'-GGGGAATCTCC-3'. The model corresponds to the DEUBAD domain (conserved domain within the UCH regulatory proteins RPN13, NFRKB/INO80G, and ASX) of NFRKB, which binds primarily to the C-terminal ULD domain of UCH-L5.
Pssm-ID: 439381 Cd Length: 112 Bit Score: 180.87 E-value: 4.90e-53
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ...
981-1187
6.87e-03
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.
Pssm-ID: 282904 [Multi-domain] Cd Length: 886 Bit Score: 40.67 E-value: 6.87e-03
Database: CDSEARCH/cdd Low complexity filter: no Composition Based Adjustment: yes E-value threshold: 0.01
References:
Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
of the residues that compose this conserved feature have been mapped to the query sequence.
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(labeled illustration) Standard Display shows only the best scoring domain model from each source, in each hit category listed below for each region on the query sequence.
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