NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|564391042|ref|XP_006253869|]
View 

biogenesis of lysosome-related organelles complex 1 subunit 5 isoform X1 [Rattus norvegicus]

Protein Classification

Muted domain-containing protein( domain architecture ID 10633104)

Muted domain-containing protein

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
Muted pfam14942
Organelle biogenesis, Muted-like protein; The protein is a coiled-coil protein and belongs to ...
 36-226 6.58e-65

Organelle biogenesis, Muted-like protein; The protein is a coiled-coil protein and belongs to a family found in eukaryotes. It undergoes alternative splicing forming two isoforms. The larger isoform is 187 amino acids long in protein sequence length and 21 kDa in mass. The smaller isoform is 110 amino acids long in protein sequence length and 12 kDa in mass. This protein associates with other proteins in order to form biogenesis of lysosome-related organelles complex-1 BLOC1 complex. BLOC-1 is required for the normal biogenesis of specialized organelles of the endosomal-lysosomal system.


:

Pssm-ID: 464390 [Multi-domain]  Cd Length: 146  Bit Score: 197.88  E-value: 6.58e-65
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564391042   36 IKDLGEIHSRLLDHRPVTQGEIRYFVKEFEEKRGLRELRVLENLKNMIQETNERMLPKCRETMQGGLEETLQRLQAATDS 115
Cdd:pfam14942   1 IKDIGEIYSRLLDHRPFIQGEIKYFLKEFEEKRGDREVRRLENITEMINETNENILPKCKQSMEDNLSELLSKLDAALNM 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564391042  116 IHRLQQREQERKKTgtrdpglvdlgallssellprssclytpsparsysgllhphdlyvINDHLTASEKQRMLQWEEFLR 195
Cdd:pfam14942  81 CERLLQRELEEEQR---------------------------------------------KNDRLQENEEQRKAEWEEFMK 115

                         170       180       190
                  ....*....|....*....|....*....|.
gi 564391042  196 GQPQRRAEVDAEHRKAMERLREQYAAMEKDL 226
Cdd:pfam14942 116 EQQEKKAEVDEEFNEKMERLKEQYSELEKKL 146
 
Name Accession Description Interval E-value
Muted pfam14942
Organelle biogenesis, Muted-like protein; The protein is a coiled-coil protein and belongs to ...
 36-226 6.58e-65

Organelle biogenesis, Muted-like protein; The protein is a coiled-coil protein and belongs to a family found in eukaryotes. It undergoes alternative splicing forming two isoforms. The larger isoform is 187 amino acids long in protein sequence length and 21 kDa in mass. The smaller isoform is 110 amino acids long in protein sequence length and 12 kDa in mass. This protein associates with other proteins in order to form biogenesis of lysosome-related organelles complex-1 BLOC1 complex. BLOC-1 is required for the normal biogenesis of specialized organelles of the endosomal-lysosomal system.


Pssm-ID: 464390 [Multi-domain]  Cd Length: 146  Bit Score: 197.88  E-value: 6.58e-65
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564391042   36 IKDLGEIHSRLLDHRPVTQGEIRYFVKEFEEKRGLRELRVLENLKNMIQETNERMLPKCRETMQGGLEETLQRLQAATDS 115
Cdd:pfam14942   1 IKDIGEIYSRLLDHRPFIQGEIKYFLKEFEEKRGDREVRRLENITEMINETNENILPKCKQSMEDNLSELLSKLDAALNM 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564391042  116 IHRLQQREQERKKTgtrdpglvdlgallssellprssclytpsparsysgllhphdlyvINDHLTASEKQRMLQWEEFLR 195
Cdd:pfam14942  81 CERLLQRELEEEQR---------------------------------------------KNDRLQENEEQRKAEWEEFMK 115

                         170       180       190
                  ....*....|....*....|....*....|.
gi 564391042  196 GQPQRRAEVDAEHRKAMERLREQYAAMEKDL 226
Cdd:pfam14942 116 EQQEKKAEVDEEFNEKMERLKEQYSELEKKL 146
 
Name Accession Description Interval E-value
Muted pfam14942
Organelle biogenesis, Muted-like protein; The protein is a coiled-coil protein and belongs to ...
 36-226 6.58e-65

Organelle biogenesis, Muted-like protein; The protein is a coiled-coil protein and belongs to a family found in eukaryotes. It undergoes alternative splicing forming two isoforms. The larger isoform is 187 amino acids long in protein sequence length and 21 kDa in mass. The smaller isoform is 110 amino acids long in protein sequence length and 12 kDa in mass. This protein associates with other proteins in order to form biogenesis of lysosome-related organelles complex-1 BLOC1 complex. BLOC-1 is required for the normal biogenesis of specialized organelles of the endosomal-lysosomal system.


Pssm-ID: 464390 [Multi-domain]  Cd Length: 146  Bit Score: 197.88  E-value: 6.58e-65
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564391042   36 IKDLGEIHSRLLDHRPVTQGEIRYFVKEFEEKRGLRELRVLENLKNMIQETNERMLPKCRETMQGGLEETLQRLQAATDS 115
Cdd:pfam14942   1 IKDIGEIYSRLLDHRPFIQGEIKYFLKEFEEKRGDREVRRLENITEMINETNENILPKCKQSMEDNLSELLSKLDAALNM 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564391042  116 IHRLQQREQERKKTgtrdpglvdlgallssellprssclytpsparsysgllhphdlyvINDHLTASEKQRMLQWEEFLR 195
Cdd:pfam14942  81 CERLLQRELEEEQR---------------------------------------------KNDRLQENEEQRKAEWEEFMK 115

                         170       180       190
                  ....*....|....*....|....*....|.
gi 564391042  196 GQPQRRAEVDAEHRKAMERLREQYAAMEKDL 226
Cdd:pfam14942 116 EQQEKKAEVDEEFNEKMERLKEQYSELEKKL 146
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH