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Conserved domains on  [gi|672036538|ref|XP_008757620|]
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tubby-related protein 2 isoform X9 [Rattus norvegicus]

Protein Classification

tubby family protein( domain architecture ID 10471804)

tubby family protein plays an important role in maintenance and function of neuronal cells during post differentiation and development in mammals, and may participate in the abscisic acid (ABA) signaling pathway in plants

CATH:  3.20.90.10
Gene Ontology:  GO:0006355
PubMed:  21722349
SCOP:  4001052

Graphical summary

 Zoom to residue level

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List of domain hits

Name Accession Description Interval E-value
Tub pfam01167
Tub family;
196-445 6.21e-131

Tub family;


:

Pssm-ID: 460094  Cd Length: 251  Bit Score: 378.07  E-value: 6.21e-131
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672036538  196 PAPREHMVQCRIVRNKHGVdkGMFPSYYLYLEAEDGvavRSsplGHFLLAGRKRKRSKTSNYLISLDPKDMSRNGNNFVG 275
Cdd:pfam01167   3 PGPRDGTIQCFIKRDKSGM--GLTPTYHLYLELSPG---DG---GKFLLAARKRRRSTTSNYLISLDADDLSRGSNGYIG 74
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672036538  276 KVRSNVLGTKFTIFDN-----GVNPERNYWIPDSARI---REELGVVCYETNVLGFRGPRKMTVILPGMDSRKQRMKVQP 347
Cdd:pfam01167  75 KLRSNFLGTKFTLYDNqppynGANPSKSRSSFGSKKVspgRYELAAVSYELNVLGTRGPRRMKVIIPSIPASGQQVPIQP 154
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672036538  348 QNDqDSILSRVQKGARHGLLLLQNKAPSWSDESGAYVLNFHGRVTRASVKNFQIVHPDEPDHLVLQFGRVAPNIFTMDFR 427
Cdd:pfam01167 155 QSE-SSLLEDFKSGRLDELLVLKNKPPRWNEQLQCYCLNFHGRVTVASVKNFQLVAPEDQDKVILQFGKVGKDMFTMDYR 233
                         250
                  ....*....|....*...
gi 672036538  428 YPLCPLQAFAICLSSFDG 445
Cdd:pfam01167 234 YPLSAFQAFAICLSSFDT 251
 
Name Accession Description Interval E-value
Tub pfam01167
Tub family;
196-445 6.21e-131

Tub family;


Pssm-ID: 460094  Cd Length: 251  Bit Score: 378.07  E-value: 6.21e-131
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672036538  196 PAPREHMVQCRIVRNKHGVdkGMFPSYYLYLEAEDGvavRSsplGHFLLAGRKRKRSKTSNYLISLDPKDMSRNGNNFVG 275
Cdd:pfam01167   3 PGPRDGTIQCFIKRDKSGM--GLTPTYHLYLELSPG---DG---GKFLLAARKRRRSTTSNYLISLDADDLSRGSNGYIG 74
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672036538  276 KVRSNVLGTKFTIFDN-----GVNPERNYWIPDSARI---REELGVVCYETNVLGFRGPRKMTVILPGMDSRKQRMKVQP 347
Cdd:pfam01167  75 KLRSNFLGTKFTLYDNqppynGANPSKSRSSFGSKKVspgRYELAAVSYELNVLGTRGPRRMKVIIPSIPASGQQVPIQP 154
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672036538  348 QNDqDSILSRVQKGARHGLLLLQNKAPSWSDESGAYVLNFHGRVTRASVKNFQIVHPDEPDHLVLQFGRVAPNIFTMDFR 427
Cdd:pfam01167 155 QSE-SSLLEDFKSGRLDELLVLKNKPPRWNEQLQCYCLNFHGRVTVASVKNFQLVAPEDQDKVILQFGKVGKDMFTMDYR 233
                         250
                  ....*....|....*...
gi 672036538  428 YPLCPLQAFAICLSSFDG 445
Cdd:pfam01167 234 YPLSAFQAFAICLSSFDT 251
 
Name Accession Description Interval E-value
Tub pfam01167
Tub family;
196-445 6.21e-131

Tub family;


Pssm-ID: 460094  Cd Length: 251  Bit Score: 378.07  E-value: 6.21e-131
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672036538  196 PAPREHMVQCRIVRNKHGVdkGMFPSYYLYLEAEDGvavRSsplGHFLLAGRKRKRSKTSNYLISLDPKDMSRNGNNFVG 275
Cdd:pfam01167   3 PGPRDGTIQCFIKRDKSGM--GLTPTYHLYLELSPG---DG---GKFLLAARKRRRSTTSNYLISLDADDLSRGSNGYIG 74
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672036538  276 KVRSNVLGTKFTIFDN-----GVNPERNYWIPDSARI---REELGVVCYETNVLGFRGPRKMTVILPGMDSRKQRMKVQP 347
Cdd:pfam01167  75 KLRSNFLGTKFTLYDNqppynGANPSKSRSSFGSKKVspgRYELAAVSYELNVLGTRGPRRMKVIIPSIPASGQQVPIQP 154
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672036538  348 QNDqDSILSRVQKGARHGLLLLQNKAPSWSDESGAYVLNFHGRVTRASVKNFQIVHPDEPDHLVLQFGRVAPNIFTMDFR 427
Cdd:pfam01167 155 QSE-SSLLEDFKSGRLDELLVLKNKPPRWNEQLQCYCLNFHGRVTVASVKNFQLVAPEDQDKVILQFGKVGKDMFTMDYR 233
                         250
                  ....*....|....*...
gi 672036538  428 YPLCPLQAFAICLSSFDG 445
Cdd:pfam01167 234 YPLSAFQAFAICLSSFDT 251
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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