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Conserved domains on  [gi|672055299|ref|XP_008762686|]
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tetratricopeptide repeat protein 7A isoform X2 [Rattus norvegicus]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Spy super family cl27809
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 375-514 4.09e-20

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


The actual alignment was detected with superfamily member COG3914:

Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 93.90  E-value: 4.09e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672055299 375 LEQIWLQAAELFMEQRQLKEAGFCIQEAAGLFPTSHSVLYMRGRLAEVKGSFEEAKQLYKEALTVNPDGVCIMHSLGLIL 454
Cdd:COG3914   77 LAALLELAALLLQALGRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEAL 156

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 672055299 455 SRLGHKSLAQKVLRDAVERQSTHHEAWQGLGEVLQDQGHNEAAADCFLTALELEASSPVL 514
Cdd:COG3914  157 RRLGRLEEAIAALRRALELDPDNAEALNNLGNALQDLGRLEEAIAAYRRALELDPDNADA 216
TTC7_N super family cl44857
Tetratricopeptide repeat protein 7 N-terminal; This is the N-terminal domain of TTC7, a ...
 22-69 5.96e-19

Tetratricopeptide repeat protein 7 N-terminal; This is the N-terminal domain of TTC7, a protein that forms the regulatory subunit of the PI4KIIIalpha complex (also known as PI4KA). This complex is composed of PI4KIIIalpha, TTC7 and FAM126A and catalyzes the first step in plasma membrane phosphoinositide synthesis. This TTC7 N-terminal domain contains basic residues suitable for interaction with the acidic inner leaflet of the plasma membrane and is required for localising the active site near its substrate. TTC7 acts as a bridge between PI4KA and EFR3B-FAM126A, via direct interactions. ERF3B is not part of the complex but contributes to its recruitment to the membrane.


The actual alignment was detected with superfamily member pfam19440:

Pssm-ID: 466084  Cd Length: 386  Bit Score: 88.68  E-value: 5.96e-19
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*...
gi 672055299   22 ATRDVVLSRAPEQEEDRKVSLQNASAIYDLLSITLGRRGQYVMLSECL 69
Cdd:pfam19440 339 ANRDAVLSRSPEHREARIISLQNATAVYDLLTIAMGRRGQYEMLSECL 386
3a0801s09 super family cl36792
mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) ...
 163-508 5.65e-08

mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70); [Transport and binding proteins, Amino acids, peptides and amines]


The actual alignment was detected with superfamily member TIGR00990:

Pssm-ID: 273380 [Multi-domain]  Cd Length: 615  Bit Score: 55.38  E-value: 5.65e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672055299  163 YSLQATDATLKSKQDELHRKALQTLERALELAPDDpqiIFYVSLQLA--LVRQISSAIERLQEALTVCRDDANALHLLAL 240
Cdd:TIGR00990 126 YAAKLKEKGNKAYRNKDFNKAIKLYSKAIECKPDP---VYYSNRAAChnALGDWEKVVEDTTAALELDPDYSKALNRRAN 202

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672055299  241 LFSAQKHHQHAL----------DVINMAITEHPENFNLMFTKVKLEQVLKGPEEALVTCRQMLRLWQALYNFSQLGGLEK 310
Cdd:TIGR00990 203 AYDGLGKYADALldltasciidGFRNEQSAQAVERLLKKFAESKAKEILETKPENLPSVTFVGNYLQSFRPKPRPAGLED 282

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672055299  311 DGSFEGLTVKKQNGIHLTLPDAhDADSGSRRASSIAASRLE-------EAMS-ELTITTSVLKQGP----------MQLW 372
Cdd:TIGR00990 283 SNELDEETGNGQLQLGLKSPES-KADESYEEAARAFEKALDlgklgekEAIAlNLRGTFKCLKGKHlealadlsksIELD 361

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672055299  373 TTLEQIWLQAAELFMEQRQLKEAGFCIQEAAGLFPTSHSVLYMRGRLAEVKGSFEEAKQLYKEALTVNPDGVCIMHSLGL 452
Cdd:TIGR00990 362 PRVTQSYIKRASMNLELGDPDKAEEDFDKALKLNSEDPDIYYHRAQLHFIKGEFAQAGKDYQKSIDLDPDFIFSHIQLGV 441

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 672055299  453 ILSRLGHKSLAQKVLRDAVERQSTHHEAWQGLGEVLQDQGHNEAAADCFLTALELE 508
Cdd:TIGR00990 442 TQYKEGSIASSMATFRRCKKNFPEAPDVYNYYGELLLDQNKFDEAIEKFDTAIELE 497
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 43-123 8.72e-04

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


:

Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 39.79  E-value: 8.72e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672055299  43 QNASAiYDLLSITLGRRGQYVMLSECLERAMKYAFGEFHLWYQVALSMVACGKSAYAVSLLRECMKLQPSNPTVPLMAAK 122
Cdd:COG4783   36 DNPEA-FALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKAGDYDEALALLEKALKLDPEHPEAYLRLAR 114


                 .
gi 672055299 123 V 123
Cdd:COG4783  115 A 115
 
Name Accession Description Interval E-value
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 375-514 4.09e-20

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 93.90  E-value: 4.09e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672055299 375 LEQIWLQAAELFMEQRQLKEAGFCIQEAAGLFPTSHSVLYMRGRLAEVKGSFEEAKQLYKEALTVNPDGVCIMHSLGLIL 454
Cdd:COG3914   77 LAALLELAALLLQALGRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEAL 156

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 672055299 455 SRLGHKSLAQKVLRDAVERQSTHHEAWQGLGEVLQDQGHNEAAADCFLTALELEASSPVL 514
Cdd:COG3914  157 RRLGRLEEAIAALRRALELDPDNAEALNNLGNALQDLGRLEEAIAAYRRALELDPDNADA 216
TTC7_N pfam19440
Tetratricopeptide repeat protein 7 N-terminal; This is the N-terminal domain of TTC7, a ...
 22-69 5.96e-19

Tetratricopeptide repeat protein 7 N-terminal; This is the N-terminal domain of TTC7, a protein that forms the regulatory subunit of the PI4KIIIalpha complex (also known as PI4KA). This complex is composed of PI4KIIIalpha, TTC7 and FAM126A and catalyzes the first step in plasma membrane phosphoinositide synthesis. This TTC7 N-terminal domain contains basic residues suitable for interaction with the acidic inner leaflet of the plasma membrane and is required for localising the active site near its substrate. TTC7 acts as a bridge between PI4KA and EFR3B-FAM126A, via direct interactions. ERF3B is not part of the complex but contributes to its recruitment to the membrane.


Pssm-ID: 466084  Cd Length: 386  Bit Score: 88.68  E-value: 5.96e-19
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*...
gi 672055299   22 ATRDVVLSRAPEQEEDRKVSLQNASAIYDLLSITLGRRGQYVMLSECL 69
Cdd:pfam19440 339 ANRDAVLSRSPEHREARIISLQNATAVYDLLTIAMGRRGQYEMLSECL 386
3a0801s09 TIGR00990
mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) ...
 163-508 5.65e-08

mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70); [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273380 [Multi-domain]  Cd Length: 615  Bit Score: 55.38  E-value: 5.65e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672055299  163 YSLQATDATLKSKQDELHRKALQTLERALELAPDDpqiIFYVSLQLA--LVRQISSAIERLQEALTVCRDDANALHLLAL 240
Cdd:TIGR00990 126 YAAKLKEKGNKAYRNKDFNKAIKLYSKAIECKPDP---VYYSNRAAChnALGDWEKVVEDTTAALELDPDYSKALNRRAN 202

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672055299  241 LFSAQKHHQHAL----------DVINMAITEHPENFNLMFTKVKLEQVLKGPEEALVTCRQMLRLWQALYNFSQLGGLEK 310
Cdd:TIGR00990 203 AYDGLGKYADALldltasciidGFRNEQSAQAVERLLKKFAESKAKEILETKPENLPSVTFVGNYLQSFRPKPRPAGLED 282

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672055299  311 DGSFEGLTVKKQNGIHLTLPDAhDADSGSRRASSIAASRLE-------EAMS-ELTITTSVLKQGP----------MQLW 372
Cdd:TIGR00990 283 SNELDEETGNGQLQLGLKSPES-KADESYEEAARAFEKALDlgklgekEAIAlNLRGTFKCLKGKHlealadlsksIELD 361

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672055299  373 TTLEQIWLQAAELFMEQRQLKEAGFCIQEAAGLFPTSHSVLYMRGRLAEVKGSFEEAKQLYKEALTVNPDGVCIMHSLGL 452
Cdd:TIGR00990 362 PRVTQSYIKRASMNLELGDPDKAEEDFDKALKLNSEDPDIYYHRAQLHFIKGEFAQAGKDYQKSIDLDPDFIFSHIQLGV 441

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 672055299  453 ILSRLGHKSLAQKVLRDAVERQSTHHEAWQGLGEVLQDQGHNEAAADCFLTALELE 508
Cdd:TIGR00990 442 TQYKEGSIASSMATFRRCKKNFPEAPDVYNYYGELLLDQNKFDEAIEKFDTAIELE 497
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 126-295 2.33e-06

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 50.38  E-value: 2.33e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672055299 126 GSLHWLEEAEHFAMVVIGLGEEAGEFLPKGYLALGLTYSLQATDATLKSKQDelHRKALQTLERALELAPDDPQIIFYVS 205
Cdd:COG3914   42 GLALLLLAALAEAAAAALLALAAGEAAAAAAALLLLAALLELAALLLQALGR--YEEALALYRRALALNPDNAEALFNLG 119

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672055299 206 LQLALVRQISSAIERLQEALTVCRDDANALHLLALLFSAQKHHQHALDVINMAITEHPENFNLMFTKVKLEQVLKGPEEA 285
Cdd:COG3914  120 NLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLGRLEEAIAALRRALELDPDNAEALNNLGNALQDLGRLEEA 199

                        170
                 ....*....|
gi 672055299 286 LVTCRQMLRL 295
Cdd:COG3914  200 IAAYRRALEL 209
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 380-505 2.81e-05

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 47.00  E-value: 2.81e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672055299  380 LQAAELFMEQRQLKEAGFCIQEAAGLFPTSHSVLYMRGRLAEVKGSFEEAKQLYKEALTVNPDGVCIMHSLGLILSRLGH 459
Cdd:TIGR02917 163 LGLAQLALAENRFDEARALIDEVLTADPGNVDALLLKGDLLLSLGNIELALAAYRKAIALRPNNIAVLLALATILIEAGE 242

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*.
gi 672055299  460 KSLAQKVLRDAVERQSTHHEAWQGLGEVLQDQGHNEAAADCFLTAL 505
Cdd:TIGR02917 243 FEEAEKHADALLKKAPNSPLAHYLKALVDFQKKNYEDARETLQDAL 288
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 43-123 8.72e-04

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 39.79  E-value: 8.72e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672055299  43 QNASAiYDLLSITLGRRGQYVMLSECLERAMKYAFGEFHLWYQVALSMVACGKSAYAVSLLRECMKLQPSNPTVPLMAAK 122
Cdd:COG4783   36 DNPEA-FALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKAGDYDEALALLEKALKLDPEHPEAYLRLAR 114


                 .
gi 672055299 123 V 123
Cdd:COG4783  115 A 115
YPP1 cd23270
cargo-transport protein YPP1; This family includes YGR198w (named YPP1, also called ...
 150-219 1.62e-03

cargo-transport protein YPP1; This family includes YGR198w (named YPP1, also called alpha-synuclein protective protein 1), which is essential in Saccharomyces cerevisiae. It has also been shown to perform fundamental functions in human and mouse. YPP1 is a cargo-transport protein involved in endocytosis. It interacts with genes involved in protein sorting and secretion, and plays a role in the assembly and recruitment of multiple copies of the kinase into phosphoinositide kinase (PIK) patches at the plasma membrane. It has been found to suppress the toxicity of alpha-synuclein (alpha-syn) mutant (A30P) that is associated with early onset of Parkinson's disease (PD) in humans, but not wild-type or the A53T mutant (also associated with early onset PD).


Pssm-ID: 438014 [Multi-domain]  Cd Length: 740  Bit Score: 41.11  E-value: 1.62e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 672055299 150 EFLPKGYLALGLTYSLQATDATLKSKQDELHRKALQTLERALELAPD-DPQIIFYVSLQLALVRQISSAIE 219
Cdd:cd23270  391 KILSKAWYALYEYYSYLLIYTSNESELELNSNDLLSYLKNSLIVNPTgNSDLLFQYAYTLAQQREIEPAIK 461
TPR_11 pfam13414
TPR repeat;
423-458 4.55e-03

TPR repeat;


Pssm-ID: 315977 [Multi-domain]  Cd Length: 42  Bit Score: 35.14  E-value: 4.55e-03
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 672055299  423 KGSFEEAKQLYKEALTVNPDGVCIMHSLGLILSRLG 458
Cdd:pfam13414   7 QGKYEEAIEAYKKALKLDPDNPEAYYNLGLAYYKLG 42
TPR_20 pfam14561
Tetratricopeptide repeat;
184-221 7.66e-03

Tetratricopeptide repeat;


Pssm-ID: 434039 [Multi-domain]  Cd Length: 90  Bit Score: 35.95  E-value: 7.66e-03
                          10        20        30
                  ....*....|....*....|....*....|....*...
gi 672055299  184 LQTLERALELAPDDPQIIFYVSLQLALVRQISSAIERL 221
Cdd:pfam14561   8 LAALEARLAADPDDLDARLDLALALHAAGRNEEALELL 45
 
Name Accession Description Interval E-value
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 375-514 4.09e-20

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 93.90  E-value: 4.09e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672055299 375 LEQIWLQAAELFMEQRQLKEAGFCIQEAAGLFPTSHSVLYMRGRLAEVKGSFEEAKQLYKEALTVNPDGVCIMHSLGLIL 454
Cdd:COG3914   77 LAALLELAALLLQALGRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEAL 156

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 672055299 455 SRLGHKSLAQKVLRDAVERQSTHHEAWQGLGEVLQDQGHNEAAADCFLTALELEASSPVL 514
Cdd:COG3914  157 RRLGRLEEAIAALRRALELDPDNAEALNNLGNALQDLGRLEEAIAAYRRALELDPDNADA 216
TTC7_N pfam19440
Tetratricopeptide repeat protein 7 N-terminal; This is the N-terminal domain of TTC7, a ...
 22-69 5.96e-19

Tetratricopeptide repeat protein 7 N-terminal; This is the N-terminal domain of TTC7, a protein that forms the regulatory subunit of the PI4KIIIalpha complex (also known as PI4KA). This complex is composed of PI4KIIIalpha, TTC7 and FAM126A and catalyzes the first step in plasma membrane phosphoinositide synthesis. This TTC7 N-terminal domain contains basic residues suitable for interaction with the acidic inner leaflet of the plasma membrane and is required for localising the active site near its substrate. TTC7 acts as a bridge between PI4KA and EFR3B-FAM126A, via direct interactions. ERF3B is not part of the complex but contributes to its recruitment to the membrane.


Pssm-ID: 466084  Cd Length: 386  Bit Score: 88.68  E-value: 5.96e-19
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*...
gi 672055299   22 ATRDVVLSRAPEQEEDRKVSLQNASAIYDLLSITLGRRGQYVMLSECL 69
Cdd:pfam19440 339 ANRDAVLSRSPEHREARIISLQNATAVYDLLTIAMGRRGQYEMLSECL 386
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
377-508 1.68e-16

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 79.28  E-value: 1.68e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672055299 377 QIWLQAAELFMEQRQLKEAGFCIQEAAGLFPTSHSVLYMRGRLAEVKGSFEEAKQLYKEALTVNPDGVCIMHSLGLILSR 456
Cdd:COG0457    9 EAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLALQA 88

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|..
gi 672055299 457 LGHKSLAQKVLRDAVERQSTHHEAWQGLGEVLQDQGHNEAAADCFLTALELE 508
Cdd:COG0457   89 LGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELD 140
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 377-509 8.19e-15

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 71.38  E-value: 8.19e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672055299 377 QIWLQAAELFMEQRQLKEAGFCIQEAAGLFPTSHSVLYMRGRLAEVKGSFEEAKQLYKEALTVNPDGVCIMHSLGLILSR 456
Cdd:COG4783    5 EALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLK 84

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|...
gi 672055299 457 LGHKSLAQKVLRDAVERQSTHHEAWQGLGEVLQDQGHNEAAADCFLTALELEA 509
Cdd:COG4783   85 AGDYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALELDP 137
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 376-514 1.76e-13

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 70.91  E-value: 1.76e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672055299 376 EQIWLQAAELFMEQRQLKEAGFCIQEAAGLFPTSHSVLYMRGRLAEVKGSFEEAKQLYKEALTVNPDGVCIMHSLGLILS 455
Cdd:COG2956  110 AEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKALKLDPDCARALLLLAELYL 189

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 672055299 456 RLGHKSLAQKVLRDAVERQSTHHEAWQGLGEVLQDQGHNEAAADCFLTALELEASSPVL 514
Cdd:COG2956  190 EQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEALELLRKALELDPSDDLL 248
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 375-512 2.46e-13

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 72.72  E-value: 2.46e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672055299 375 LEQIWLQAAELFMEQRQLKEAGFCIQEAAGLFPTSHSVLYMRGRLAEVKGSFEEAKQLYKEALTVNPDGVCIMHSLGLIL 454
Cdd:COG3914   43 LALLLLAALAEAAAAALLALAAGEAAAAAAALLLLAALLELAALLLQALGRYEEALALYRRALALNPDNAEALFNLGNLL 122

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 672055299 455 SRLGHKSLAQKVLRDAVERQSTHHEAWQGLGEVLQDQGHNEAAADCFLTALELEASSP 512
Cdd:COG3914  123 LALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLGRLEEAIAALRRALELDPDNA 180
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
377-509 5.34e-13

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 68.88  E-value: 5.34e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672055299 377 QIWLQAAELFMEQRQLKEAGFCIQEAAGLFPTSHSVLYMRGRLAEVKGSFEEAKQLYKEALTVNPDGVCIMHSLGLILSR 456
Cdd:COG0457   43 EALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLE 122

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|...
gi 672055299 457 LGHKSLAQKVLRDAVERQSTHHEAWQGLGEVLQDQGHNEAAADCFLTALELEA 509
Cdd:COG0457  123 LGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRYEEALELLEKLEAAAL 175
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
405-512 1.31e-12

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 67.72  E-value: 1.31e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672055299 405 LFPTSHSVLYMRGRLAEVKGSFEEAKQLYKEALTVNPDGVCIMHSLGLILSRLGHKSLAQKVLRDAVERQSTHHEAWQGL 484
Cdd:COG0457    3 LDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNL 82

                         90       100
                 ....*....|....*....|....*...
gi 672055299 485 GEVLQDQGHNEAAADCFLTALELEASSP 512
Cdd:COG0457   83 GLALQALGRYEEALEDYDKALELDPDDA 110
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 376-508 3.91e-12

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 66.68  E-value: 3.91e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672055299 376 EQIWLQAAELFMEQRQLKEAGFCIQEAAGLFPTSHSVLYMRGRLAEVKGSFEEAKQLYKEALTVNPDGVCIMHSLGLILS 455
Cdd:COG2956   76 AEALLELAQDYLKAGLLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYL 155

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|...
gi 672055299 456 RLGHKSLAQKVLRDAVERQSTHHEAWQGLGEVLQDQGHNEAAADCFLTALELE 508
Cdd:COG2956  156 EQGDYDEAIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALEQD 208
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 411-512 4.00e-12

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 63.67  E-value: 4.00e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672055299 411 SVLYMRGRLAEVKGSFEEAKQLYKEALTVNPDGVCIMHSLGLILSRLGHKSLAQKVLRDAVERQSTHHEAWQGLGEVLQD 490
Cdd:COG4783    5 EALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLK 84

                         90       100
                 ....*....|....*....|..
gi 672055299 491 QGHNEAAADCFLTALELEASSP 512
Cdd:COG4783   85 AGDYDEALALLEKALKLDPEHP 106
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 376-506 2.21e-11

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 64.37  E-value: 2.21e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672055299 376 EQIWLQAAELFMEQRQLKEAGFCIQEAAGLFPTSHSVLYMRGRLAEVKGSFEEAKQLYKEALTVNPDGVCIMHSLGLILS 455
Cdd:COG2956  144 AHAYCELAELYLEQGDYDEAIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYE 223

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|.
gi 672055299 456 RLGHKSLAQKVLRDAVERQSThHEAWQGLGEVLQDQGHNEAAADCFLTALE 506
Cdd:COG2956  224 KLGDPEEALELLRKALELDPS-DDLLLALADLLERKEGLEAALALLERQLR 273
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 394-507 2.07e-10

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 58.48  E-value: 2.07e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672055299 394 EAGFCIQEAAGLFPTSHSVLYMRGRLAEVKGSFEEAKQLYKEALTVNPDGVCIMHSLGLILSRLGHKSLAQKVLRDAVER 473
Cdd:COG4235    1 EAIARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALAL 80

                         90       100       110
                 ....*....|....*....|....*....|....
gi 672055299 474 QSTHHEAWQGLGEVLQDQGHNEAAADCFLTALEL 507
Cdd:COG4235   81 DPDNPEALYLLGLAAFQQGDYAEAIAAWQKLLAL 114
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 423-508 5.07e-10

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 58.05  E-value: 5.07e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672055299 423 KGSFEEAKQLYKEALTVNPDGVCIMHSLGLILSRLGHKSLAQKVLRDAVERQSTHHEAWQGLGEVLQDQGHNEAAADCFL 502
Cdd:COG5010   67 LGDFEESLALLEQALQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAALQ 146


                 ....*.
gi 672055299 503 TALELE 508
Cdd:COG5010  147 RALGTS 152
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 379-507 5.30e-10

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 60.51  E-value: 5.30e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672055299 379 WLQAAELFMEQRQLKEAGFCIQEAAGLFPTSHSVLYMRGRLAEVKGSFEEAKQLYKEALTVNPDGVCIMHSLGLILSRLG 458
Cdd:COG2956   11 WYFKGLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAG 90

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*....
gi 672055299 459 HKSLAQKVLRDAVERQSTHHEAWQGLGEVLQDQGHNEAAADCFLTALEL 507
Cdd:COG2956   91 LLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKL 139
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 377-520 9.03e-10

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 61.16  E-value: 9.03e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672055299 377 QIWLQAAELFMEQRQLKEAGFCIQEAAGLFPTSHSVLYMRGRLAEVKGSFEEAKQLYKEALTVNPDGVCIMHSLGLILSR 456
Cdd:COG3914  113 EALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLGRLEEAIAALRRALELDPDNAEALNNLGNALQD 192

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 672055299 457 LGHKSLAQKVLRDAVERQSTHHEAWQGLGEVLQDQGHNEAAADCFLTALELEASSPVL-PFSIIA 520
Cdd:COG3914  193 LGRLEEAIAAYRRALELDPDNADAHSNLLFALRQACDWEVYDRFEELLAALARGPSELsPFALLY 257
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
423-510 5.52e-09

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 53.25  E-value: 5.52e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672055299 423 KGSFEEAKQLYKEALTVNPDGVCIMHSLGLILSRLGHKSLAQKvLRDAVERQSTHHEAWQGLGEVLQDQGHNEAAADCFL 502
Cdd:COG3063    5 LGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIA-LEKALKLDPNNAEALLNLAELLLELGDYDEALAYLE 83


                 ....*...
gi 672055299 503 TALELEAS 510
Cdd:COG3063   84 RALELDPS 91
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 377-512 7.42e-09

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 57.05  E-value: 7.42e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672055299 377 QIWLQAAELFMEQRQLKEAGFCIQEAAGLFPTSHSVLYMRGRLAEVKGSFEEAKQLYKEALTVNPDGVCIMHSLGLILSR 456
Cdd:COG2956   43 EAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGLLDRAEELLEKLLELDPDDAEALRLLAEIYEQ 122

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 672055299 457 LGHKSLAQKVLRDAVERQSTHHEAWQGLGEVLQDQGHNEAAADCFLTALELEASSP 512
Cdd:COG2956  123 EGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKALKLDPDCA 178
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 414-512 1.04e-08

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 56.28  E-value: 1.04e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672055299 414 YMRGRLAEVKGSFEEAKQLYKEALTVNPDGVCIMHSLGLILSRLGHKSLAQKVLRDAVERQSTHHEAWQGLGEVLQDQGH 493
Cdd:COG2956   12 YFKGLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGL 91

                         90
                 ....*....|....*....
gi 672055299 494 NEAAADCFLTALELEASSP 512
Cdd:COG2956   92 LDRAEELLEKLLELDPDDA 110
3a0801s09 TIGR00990
mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) ...
 163-508 5.65e-08

mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70); [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273380 [Multi-domain]  Cd Length: 615  Bit Score: 55.38  E-value: 5.65e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672055299  163 YSLQATDATLKSKQDELHRKALQTLERALELAPDDpqiIFYVSLQLA--LVRQISSAIERLQEALTVCRDDANALHLLAL 240
Cdd:TIGR00990 126 YAAKLKEKGNKAYRNKDFNKAIKLYSKAIECKPDP---VYYSNRAAChnALGDWEKVVEDTTAALELDPDYSKALNRRAN 202

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672055299  241 LFSAQKHHQHAL----------DVINMAITEHPENFNLMFTKVKLEQVLKGPEEALVTCRQMLRLWQALYNFSQLGGLEK 310
Cdd:TIGR00990 203 AYDGLGKYADALldltasciidGFRNEQSAQAVERLLKKFAESKAKEILETKPENLPSVTFVGNYLQSFRPKPRPAGLED 282

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672055299  311 DGSFEGLTVKKQNGIHLTLPDAhDADSGSRRASSIAASRLE-------EAMS-ELTITTSVLKQGP----------MQLW 372
Cdd:TIGR00990 283 SNELDEETGNGQLQLGLKSPES-KADESYEEAARAFEKALDlgklgekEAIAlNLRGTFKCLKGKHlealadlsksIELD 361

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672055299  373 TTLEQIWLQAAELFMEQRQLKEAGFCIQEAAGLFPTSHSVLYMRGRLAEVKGSFEEAKQLYKEALTVNPDGVCIMHSLGL 452
Cdd:TIGR00990 362 PRVTQSYIKRASMNLELGDPDKAEEDFDKALKLNSEDPDIYYHRAQLHFIKGEFAQAGKDYQKSIDLDPDFIFSHIQLGV 441

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 672055299  453 ILSRLGHKSLAQKVLRDAVERQSTHHEAWQGLGEVLQDQGHNEAAADCFLTALELE 508
Cdd:TIGR00990 442 TQYKEGSIASSMATFRRCKKNFPEAPDVYNYYGELLLDQNKFDEAIEKFDTAIELE 497
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
377-480 6.89e-08

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 53.47  E-value: 6.89e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672055299 377 QIWLQAAELFMEQRQLKEAGFCIQEAAGLFPTSHSVLYMRGRLAEVKGSFEEAKQLYKEALTVNPDGVCIMHSLGLILSR 456
Cdd:COG0457   77 EALNNLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEK 156

                         90       100
                 ....*....|....*....|....
gi 672055299 457 LGHKSLAQKVLRDAVERQSTHHEA 480
Cdd:COG0457  157 LGRYEEALELLEKLEAAALAALLA 180
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 377-482 1.40e-07

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 50.39  E-value: 1.40e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672055299 377 QIWLQAAELFMEQRQLKEAGFCIQEAAGLFPTSHSVLYMRGRLAEVKGSFEEAKQLYKEALTVNPDGVCIMHSLGLILSR 456
Cdd:COG4235   18 EGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALALDPDNPEALYLLGLAAFQ 97

                         90       100
                 ....*....|....*....|....*.
gi 672055299 457 LGHKSLAQKVLRDAVERQSTHHEAWQ 482
Cdd:COG4235   98 QGDYAEAIAAWQKLLALLPADAPARL 123
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
385-479 1.13e-06

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 46.70  E-value: 1.13e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672055299 385 LFMEQRQLKEAGFCIQEAAGLFPTSHSVLYMRGRLAEVKGSFEEAKQlYKEALTVNPDGVCIMHSLGLILSRLGHKSLAQ 464
Cdd:COG3063    1 LYLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIA-LEKALKLDPNNAEALLNLAELLLELGDYDEAL 79

                         90
                 ....*....|....*
gi 672055299 465 KVLRDAVERQSTHHE 479
Cdd:COG3063   80 AYLERALELDPSALR 94
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 126-295 2.33e-06

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 50.38  E-value: 2.33e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672055299 126 GSLHWLEEAEHFAMVVIGLGEEAGEFLPKGYLALGLTYSLQATDATLKSKQDelHRKALQTLERALELAPDDPQIIFYVS 205
Cdd:COG3914   42 GLALLLLAALAEAAAAALLALAAGEAAAAAAALLLLAALLELAALLLQALGR--YEEALALYRRALALNPDNAEALFNLG 119

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672055299 206 LQLALVRQISSAIERLQEALTVCRDDANALHLLALLFSAQKHHQHALDVINMAITEHPENFNLMFTKVKLEQVLKGPEEA 285
Cdd:COG3914  120 NLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLGRLEEAIAALRRALELDPDNAEALNNLGNALQDLGRLEEA 199

                        170
                 ....*....|
gi 672055299 286 LVTCRQMLRL 295
Cdd:COG3914  200 IAAYRRALEL 209
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 13-516 3.01e-06

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 50.08  E-value: 3.01e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672055299   13 KSGEDDLRQATRDVVLSRAPEQEEdrkvslqnASAIYDLLSItlgRRGQYVMLSECLERAMKYAFGEFHLWYQVALSMVA 92
Cdd:TIGR02917 239 EAGEFEEAEKHADALLKKAPNSPL--------AHYLKALVDF---QKKNYEDARETLQDALKSAPEYLPALLLAGASEYQ 307

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672055299   93 CGKSAYAVSLLRECMKLQPSNPTVPLMAAKVCIGSLHWLEeaehfAMVVIGLGEEAGEFLPKGYLALGLTYsLQATDATl 172
Cdd:TIGR02917 308 LGNLEQAYQYLNQILKYAPNSHQARRLLASIQLRLGRVDE-----AIATLSPALGLDPDDPAALSLLGEAY-LALGDFE- 380

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672055299  173 kskqdelhrKALQTLERALELAPDDPQiifyVSLQLALVR----QISSAIERLQEALTVcrDDANALHLLALLFSAQKHH 248
Cdd:TIGR02917 381 ---------KAAEYLAKATELDPENAA----ARTQLGISKlsqgDPSEAIADLETAAQL--DPELGRADLLLILSYLRSG 445

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672055299  249 Q--HALDVINMAITEHPEN---FNLMFTKVKLEQVLKGPEEALvtcRQMLRLWQAlyNFSQLGGLEKdgsfegLTVKKQN 323
Cdd:TIGR02917 446 QfdKALAAAKKLEKKQPDNaslHNLLGAIYLGKGDLAKAREAF---EKALSIEPD--FFPAAANLAR------IDIQEGN 514

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672055299  324 gihltLPDAHD-------ADSGSRRA----SSIAASRLEEAMSeltitTSVLKQgPMQLWTTLEQIWLQAAELFMEQRQL 392
Cdd:TIGR02917 515 -----PDDAIQrfekvltIDPKNLRAilalAGLYLRTGNEEEA-----VAWLEK-AAELNPQEIEPALALAQYYLGKGQL 583

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672055299  393 KEAGFCIQEAAGLFPTSHSVLYMRGRLAEVKGSFEEAKQLYKEALTVNPDGVCIMHSLGLILSRLGHKSLAQKVLRDAVE 472
Cdd:TIGR02917 584 KKALAILNEAADAAPDSPEAWLMLGRAQLAAGDLNKAVSSFKKLLALQPDSALALLLLADAYAVMKNYAKAITSLKRALE 663

                         490       500       510       520
                  ....*....|....*....|....*....|....*....|....
gi 672055299  473 RQSTHHEAWQGLGEVLQDQGHNEAAadcFLTALELEASSPVLPF 516
Cdd:TIGR02917 664 LKPDNTEAQIGLAQLLLAAKRTESA---KKIAKSLQKQHPKAAL 704
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
437-508 3.41e-06

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 48.46  E-value: 3.41e-06
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 672055299 437 LTVNPDGVCIMHSLGLILSRLGHKSLAQKVLRDAVERQSTHHEAWQGLGEVLQDQGHNEAAADCFLTALELE 508
Cdd:COG0457    1 LELDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELD 72
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
370-506 9.08e-06

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 46.83  E-value: 9.08e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672055299 370 QLWTTLEQIWLQAAELFMEQRQLKEAGFCIQEAAGLFPTSHSVLYMRGRLAEVKGSFEEAKQLYKEALTVNPDGVCIMHS 449
Cdd:COG4785   67 LALPDLAQLYYERGVAYDSLGDYDLAIADFDQALELDPDLAEAYNNRGLAYLLLGDYDAALEDFDRALELDPDYAYAYLN 146

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 672055299 450 LGLILSRLGHKSLAQKVLRDAVERQSTHHEA--WQGL------------------GEVLQDQGHNEAAADCFLTALE 506
Cdd:COG4785  147 RGIALYYLGRYELAIADLEKALELDPNDPERalWLYLaerkldpekalallledwATAYLLQGDTEEARELFKLALA 223
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 376-508 9.13e-06

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 48.45  E-value: 9.13e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672055299 376 EQIWLQAAELFMEQRQLKEAGFCIQEAAGLFPT---------SHSVLYMRGRLAEVKGSFEEAKQLYKEALTVNPDGVCI 446
Cdd:COG3914    1 AAAAALLALAALAAAALLAAAAAAELALAAELEaaalaaalgLALLLLAALAEAAAAALLALAAGEAAAAAAALLLLAAL 80

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 672055299 447 MHSLGLILSRLGHKSLAQKVLRDAVERQSTHHEAWQGLGEVLQDQGHNEAAADCFLTALELE 508
Cdd:COG3914   81 LELAALLLQALGRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRALALN 142
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 83-295 1.62e-05

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 46.65  E-value: 1.62e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672055299  83 WYQVALSMVACGKSAYAVSLLRECMKLQPSNPtvplmAAKVCIGSLHW----LEEAEHFAMVVIGLGEEAgeflPKGYLA 158
Cdd:COG2956   11 WYFKGLNYLLNGQPDKAIDLLEEALELDPETV-----EAHLALGNLYRrrgeYDRAIRIHQKLLERDPDR----AEALLE 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672055299 159 LGLTYSLQatdatlkskqdELHRKALQTLERALELAPDDPQIIFYVSLQLALVRQISSAIERLQEALTVCRDDANALHLL 238
Cdd:COG2956   82 LAQDYLKA-----------GLLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCEL 150

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 672055299 239 ALLFSAQKHHQHALDVINMAITEHPENFNLMFTKVKLEQVLKGPEEALVTCRQMLRL 295
Cdd:COG2956  151 AELYLEQGDYDEAIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALEQ 207
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 380-505 2.81e-05

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 47.00  E-value: 2.81e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672055299  380 LQAAELFMEQRQLKEAGFCIQEAAGLFPTSHSVLYMRGRLAEVKGSFEEAKQLYKEALTVNPDGVCIMHSLGLILSRLGH 459
Cdd:TIGR02917 163 LGLAQLALAENRFDEARALIDEVLTADPGNVDALLLKGDLLLSLGNIELALAAYRKAIALRPNNIAVLLALATILIEAGE 242

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*.
gi 672055299  460 KSLAQKVLRDAVERQSTHHEAWQGLGEVLQDQGHNEAAADCFLTAL 505
Cdd:TIGR02917 243 FEEAEKHADALLKKAPNSPLAHYLKALVDFQKKNYEDARETLQDAL 288
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
413-512 3.92e-05

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 44.91  E-value: 3.92e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672055299 413 LYMRGRLAEVKGSFEEAKQLYKEALTVNPDGVCIMHSLGLILSRLGHKSLAQKVLRDAVERQSTHHEAWQGLGEVLQDQG 492
Cdd:COG4785   76 YYERGVAYDSLGDYDLAIADFDQALELDPDLAEAYNNRGLAYLLLGDYDAALEDFDRALELDPDYAYAYLNRGIALYYLG 155

                         90       100
                 ....*....|....*....|
gi 672055299 493 HNEAAADCFLTALELEASSP 512
Cdd:COG4785  156 RYELAIADLEKALELDPNDP 175
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 58-294 4.59e-05

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 45.11  E-value: 4.59e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672055299  58 RRGQYVMLSECLERAMKYAFGEFHLWYQVALSMVACGKSAYAVSLLRECMKLQPSNPTVPLMAAKVCIGSLHWlEEAEHF 137
Cdd:COG2956   54 RRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGLLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDW-EKAIEV 132

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672055299 138 AMVVIGLGEEAGEFlpkgYLALGLTYslqatdatLKSKQDElhrKALQTLERALELAPDDPqiifYVSLQLALV----RQ 213
Cdd:COG2956  133 LERLLKLGPENAHA----YCELAELY--------LEQGDYD---EAIEALEKALKLDPDCA----RALLLLAELyleqGD 193

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672055299 214 ISSAIERLQEALTVCRDDANALHLLALLFSAQKHHQHALDVINMAITEHPENfNLMFTKVKLEQVLKGPEEALVTCRQML 293
Cdd:COG2956  194 YEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEALELLRKALELDPSD-DLLLALADLLERKEGLEAALALLERQL 272


                 .
gi 672055299 294 R 294
Cdd:COG2956  273 R 273
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 181-295 4.93e-05

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 45.11  E-value: 4.93e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672055299 181 RKALQTLERALELAPDDPQIIFYVSLQLALVRQISSAIERLQEALTVCRDDANALHLLALLFSAQKHHQHALDVINMAIT 260
Cdd:COG2956  127 EKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALE 206

                         90       100       110
                 ....*....|....*....|....*....|....*
gi 672055299 261 EHPENFNLMFTKVKLEQVLKGPEEALVTCRQMLRL 295
Cdd:COG2956  207 QDPDYLPALPRLAELYEKLGDPEEALELLRKALEL 241
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
180-291 6.88e-05

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 44.61  E-value: 6.88e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672055299 180 HRKALQTLERALELAPDDPQIIFYVSLQLALVRQISSAIERLQEALTVCRDDANALHLLALLFSAQKHHQHALDVINMAI 259
Cdd:COG0457   58 YEEALADYEQALELDPDDAEALNNLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERAL 137

                         90       100       110
                 ....*....|....*....|....*....|..
gi 672055299 260 TEHPENFNLMFTKVKLEQVLKGPEEALVTCRQ 291
Cdd:COG0457  138 ELDPDDADALYNLGIALEKLGRYEEALELLEK 169
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 180-295 1.11e-04

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 42.49  E-value: 1.11e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672055299 180 HRKALQTLERALELAPDDPQIIFYVSLQLALVRQISSAIERLQEALTVCRDDANALHLLALLFSAQKHHQHALDVINMAI 259
Cdd:COG4783   20 YDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKAGDYDEALALLEKAL 99

                         90       100       110
                 ....*....|....*....|....*....|....*.
gi 672055299 260 TEHPENFNLMFTKVKLEQVLKGPEEALVTCRQMLRL 295
Cdd:COG4783  100 KLDPEHPEAYLRLARAYRALGRPDEAIAALEKALEL 135
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 428-512 2.59e-04

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 41.14  E-value: 2.59e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672055299 428 EAKQLYKEALTVNPDGVCIMHSLGLILSRLGHKSLAQKVLRDAVERQSTHHEAWQGLGEVLQDQGHNEAAADCFLTALEL 507
Cdd:COG4235    1 EAIARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALAL 80


                 ....*
gi 672055299 508 EASSP 512
Cdd:COG4235   81 DPDNP 85
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 180-263 5.08e-04

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 40.71  E-value: 5.08e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672055299 180 HRKALQTLERALELAPDDPQIIFYVSLQLALVRQISSAIERLQEALTVCRDDANALHLLALLFSAQKHHQHALDVINMAI 259
Cdd:COG5010   70 FEESLALLEQALQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAALQRAL 149


                 ....
gi 672055299 260 TEHP 263
Cdd:COG5010  150 GTSP 153
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
180-305 5.67e-04

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 41.53  E-value: 5.67e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672055299 180 HRKALQTLERALELAPDDPQIIFYVSLQLALVRQISSAIERLQEALTVCRDDANALHLLALLFSAQKHHQHALDVINMAI 259
Cdd:COG0457   24 YEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLALQALGRYEEALEDYDKAL 103

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|
gi 672055299 260 TEHPENFNLMFTKVKLEQVLKGPEEALVTCRQMLRL----WQALYNFSQL 305
Cdd:COG0457  104 ELDPDDAEALYNLGLALLELGRYDEAIEAYERALELdpddADALYNLGIA 153
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 386-473 6.58e-04

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 39.59  E-value: 6.58e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672055299 386 FMEQRQLKEAGFCIQEAAGLFPTSH---SVLYMRGRLAEVKGSFEEAKQLYKEALTVNPDGVCI---MHSLGLILSRLGH 459
Cdd:COG1729    3 LLKAGDYDEAIAAFKAFLKRYPNSPlapDALYWLGEAYYALGDYDEAAEAFEKLLKRYPDSPKApdaLLKLGLSYLELGD 82

                         90
                 ....*....|....
gi 672055299 460 KSLAQKVLRDAVER 473
Cdd:COG1729   83 YDKARATLEELIKK 96
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 43-123 8.72e-04

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 39.79  E-value: 8.72e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672055299  43 QNASAiYDLLSITLGRRGQYVMLSECLERAMKYAFGEFHLWYQVALSMVACGKSAYAVSLLRECMKLQPSNPTVPLMAAK 122
Cdd:COG4783   36 DNPEA-FALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKAGDYDEALALLEKALKLDPEHPEAYLRLAR 114


                 .
gi 672055299 123 V 123
Cdd:COG4783  115 A 115
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 172-498 1.03e-03

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 41.99  E-value: 1.03e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672055299  172 LKSKQDElhrKALQTLERALELAPDDPQIIFYVslqlALVR----QISSAIERLQEALTVCRDDANALHLLALLFSAQKH 247
Cdd:TIGR02917 238 IEAGEFE---EAEKHADALLKKAPNSPLAHYLK----ALVDfqkkNYEDARETLQDALKSAPEYLPALLLAGASEYQLGN 310

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672055299  248 HQHALDVINMAITEHPENFNLMFTKVKLEQVLKGPEEALVTCRQMLRLWQALYNFSQLGGLekdgsfegltvkkqngIHL 327
Cdd:TIGR02917 311 LEQAYQYLNQILKYAPNSHQARRLLASIQLRLGRVDEAIATLSPALGLDPDDPAALSLLGE----------------AYL 374

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672055299  328 TLPDAHDA----DSGSRRASSIAASRLEEAMSEL-----TITTSVLKQGpMQLWTTLEQIWLQAAELFMEQRQLKEAGFC 398
Cdd:TIGR02917 375 ALGDFEKAaeylAKATELDPENAAARTQLGISKLsqgdpSEAIADLETA-AQLDPELGRADLLLILSYLRSGQFDKALAA 453

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672055299  399 IQEAAGLFPTSHSVLYMRGRLAEVKGSFEEAKQLYKEALTVNPDGVCIMHSLGLILSRLGHKSLAQKVLRDAVERQSTHH 478
Cdd:TIGR02917 454 AKKLEKKQPDNASLHNLLGAIYLGKGDLAKAREAFEKALSIEPDFFPAAANLARIDIQEGNPDDAIQRFEKVLTIDPKNL 533

                         330       340
                  ....*....|....*....|
gi 672055299  479 EAWQGLGEVLQDQGHNEAAA 498
Cdd:TIGR02917 534 RAILALAGLYLRTGNEEEAV 553
YPP1 cd23270
cargo-transport protein YPP1; This family includes YGR198w (named YPP1, also called ...
 150-219 1.62e-03

cargo-transport protein YPP1; This family includes YGR198w (named YPP1, also called alpha-synuclein protective protein 1), which is essential in Saccharomyces cerevisiae. It has also been shown to perform fundamental functions in human and mouse. YPP1 is a cargo-transport protein involved in endocytosis. It interacts with genes involved in protein sorting and secretion, and plays a role in the assembly and recruitment of multiple copies of the kinase into phosphoinositide kinase (PIK) patches at the plasma membrane. It has been found to suppress the toxicity of alpha-synuclein (alpha-syn) mutant (A30P) that is associated with early onset of Parkinson's disease (PD) in humans, but not wild-type or the A53T mutant (also associated with early onset PD).


Pssm-ID: 438014 [Multi-domain]  Cd Length: 740  Bit Score: 41.11  E-value: 1.62e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 672055299 150 EFLPKGYLALGLTYSLQATDATLKSKQDELHRKALQTLERALELAPD-DPQIIFYVSLQLALVRQISSAIE 219
Cdd:cd23270  391 KILSKAWYALYEYYSYLLIYTSNESELELNSNDLLSYLKNSLIVNPTgNSDLLFQYAYTLAQQREIEPAIK 461
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
49-225 1.87e-03

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 39.99  E-value: 1.87e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672055299  49 YDLLSITLGRRGQYVMLSECLERAMKYAFGEFHLWYQVALSMVACGKSAYAVSLLRECMKLQPSNPTVPLMAAKVCIgSL 128
Cdd:COG0457   11 YNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLALQ-AL 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672055299 129 HWLEEAEHFAMVVIGLGEEagefLPKGYLALGLTYSLQatdatlkskqdELHRKALQTLERALELAPDDPQIIFYVSLQL 208
Cdd:COG0457   90 GRYEEALEDYDKALELDPD----DAEALYNLGLALLEL-----------GRYDEAIEAYERALELDPDDADALYNLGIAL 154

                        170
                 ....*....|....*..
gi 672055299 209 ALVRQISSAIERLQEAL 225
Cdd:COG0457  155 EKLGRYEEALELLEKLE 171
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 153-304 2.24e-03

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 40.75  E-value: 2.24e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672055299 153 PKGYLALGLTYSLQatdatlkskqdELHRKALQTLERALELAPDDPQIIFYVSLQLALVRQISSAIERLQEALTVCRDDA 232
Cdd:COG3914  112 AEALFNLGNLLLAL-----------GRLEEALAALRRALALNPDFAEAYLNLGEALRRLGRLEEAIAALRRALELDPDNA 180

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 672055299 233 NALHLLALLFSAQKHHQHALDVINMAITEHPENF----NLMFTKVKLE--QVLKGPEEALVTCRQMLRLWQALYNFSQ 304
Cdd:COG3914  181 EALNNLGNALQDLGRLEEAIAAYRRALELDPDNAdahsNLLFALRQACdwEVYDRFEELLAALARGPSELSPFALLYL 258
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 44-231 2.90e-03

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 40.36  E-value: 2.90e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672055299  44 NASAIYDLLSITLGRRGQYVMLSECLERAMKYAFGEFHLWYQVALSMVACGKSAYAVSLLRECMKLQPSNPTVplmaakv 123
Cdd:COG3914  110 DNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLGRLEEAIAALRRALELDPDNAEA------- 182

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672055299 124 cigslhwleeaehfamvviglgeeageflpkgYLALGLTYSLQAtdatlkskqdeLHRKALQTLERALELAPDDPQIIFY 203
Cdd:COG3914  183 --------------------------------LNNLGNALQDLG-----------RLEEAIAAYRRALELDPDNADAHSN 219

                        170       180
                 ....*....|....*....|....*...
gi 672055299 204 VsLQLALVRQISSAIERLQEALTVCRDD 231
Cdd:COG3914  220 L-LFALRQACDWEVYDRFEELLAALARG 246
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 182-513 3.44e-03

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 40.07  E-value: 3.44e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672055299  182 KALQTLERALELAPDDPQIIFYVSLQLALVRQISSAIERLQEALTVCRDDANALHLLALLFSAQKHHQHALDVINMAITE 261
Cdd:TIGR02917 449 KALAAAKKLEKKQPDNASLHNLLGAIYLGKGDLAKAREAFEKALSIEPDFFPAAANLARIDIQEGNPDDAIQRFEKVLTI 528

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672055299  262 HPENFNLMFTKVKLEQVLKGPEEALVTCRQMLRL-WQALYNFSQLGG-LEKDGSF---EGLTVKKQNG------------ 324
Cdd:TIGR02917 529 DPKNLRAILALAGLYLRTGNEEEAVAWLEKAAELnPQEIEPALALAQyYLGKGQLkkaLAILNEAADAapdspeawlmlg 608

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672055299  325 -IHLTLPDAHDADSGSRRASSIA---------ASRLEEAMSELTITTSVLKQGpMQLWTTLEQIWLQAAELFMEQRQLKE 394
Cdd:TIGR02917 609 rAQLAAGDLNKAVSSFKKLLALQpdsalalllLADAYAVMKNYAKAITSLKRA-LELKPDNTEAQIGLAQLLLAAKRTES 687

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672055299  395 AGFCIQEAAGLFPTSHSVLYMRGRLAEVKGSFEEAKQLYKEALTVNPDGVCIMHsLGLILSRLGHKSLAQKVLRDAVERQ 474
Cdd:TIGR02917 688 AKKIAKSLQKQHPKAALGFELEGDLYLRQKDYPAAIQAYRKALKRAPSSQNAIK-LHRALLASGNTAEAVKTLEAWLKTH 766

                         330       340       350
                  ....*....|....*....|....*....|....*....
gi 672055299  475 STHHEAWQGLGEVLQDQGHNEAAADCFLTALELEASSPV 513
Cdd:TIGR02917 767 PNDAVLRTALAELYLAQKDYDKAIKHYQTVVKKAPDNAV 805
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 153-277 3.58e-03

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 37.68  E-value: 3.58e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672055299 153 PKGYLALGLTYSLQatdatlkskqdELHRKALQTLERALELAPDDPQIIFYVSLQLALVRQISSAIERLQEALTVCRDDA 232
Cdd:COG4235   17 AEGWLLLGRAYLRL-----------GRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALALDPDNP 85

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*
gi 672055299 233 NALHLLALLFSAQKHHQHALDVINMAITEHPENFNLMFTKVKLEQ 277
Cdd:COG4235   86 EALYLLGLAAFQQGDYAEAIAAWQKLLALLPADAPARLLEASIAE 130
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 452-513 3.92e-03

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 38.02  E-value: 3.92e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 672055299 452 LILSRLGHKSLAQKVLRDAVERQSTHHEAWQGLGEVLQDQGHNEAAADCFLTALELEASSPV 513
Cdd:COG5010   62 NLYNKLGDFEESLALLEQALQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPN 123
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 412-507 4.12e-03

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 40.07  E-value: 4.12e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672055299  412 VLYMRGRLAEVKGSFEEAKQLYKEALTVNPDGVCIMHSLGLILSRLGHKSLAQKVLRDAVERQSTHHEAWQGLGEVLQDQ 491
Cdd:TIGR02917 127 LLALRGLAYLGLGQLELAQKSYEQALAIDPRSLYAKLGLAQLALAENRFDEARALIDEVLTADPGNVDALLLKGDLLLSL 206

                          90
                  ....*....|....*.
gi 672055299  492 GHNEAAADCFLTALEL 507
Cdd:TIGR02917 207 GNIELALAAYRKAIAL 222
TPR_11 pfam13414
TPR repeat;
423-458 4.55e-03

TPR repeat;


Pssm-ID: 315977 [Multi-domain]  Cd Length: 42  Bit Score: 35.14  E-value: 4.55e-03
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 672055299  423 KGSFEEAKQLYKEALTVNPDGVCIMHSLGLILSRLG 458
Cdd:pfam13414   7 QGKYEEAIEAYKKALKLDPDNPEAYYNLGLAYYKLG 42
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 182-265 4.81e-03

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 37.48  E-value: 4.81e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672055299 182 KALQTLERALELAPDDPQIIFYVSLQLALVRQISSAIERLQEALTVCRDDANALHLLALLFSAQKHHQHALDVINMAITE 261
Cdd:COG4783   56 EAIVLLHEALELDPDEPEARLNLGLALLKAGDYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALEL 135


                 ....
gi 672055299 262 HPEN 265
Cdd:COG4783  136 DPDD 139
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 377-442 6.78e-03

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 37.09  E-value: 6.78e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 672055299 377 QIWLQAAELFMEQRQLKEAGFCIQEAAGLFPTSHSVLYMRGRLAEVKGSFEEAKQLYKEALTVNPD 442
Cdd:COG4783   73 EARLNLGLALLKAGDYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALELDPD 138
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 423-512 6.97e-03

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 36.51  E-value: 6.97e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672055299 423 KGSFEEAKQLYKEALTVNPDGVCI---MHSLGLILSRLGHKSLAQKVLRDAVERQSTHH---EAWQGLGEVLQDQGHNEA 496
Cdd:COG1729    6 AGDYDEAIAAFKAFLKRYPNSPLApdaLYWLGEAYYALGDYDEAAEAFEKLLKRYPDSPkapDALLKLGLSYLELGDYDK 85

                         90
                 ....*....|....*.
gi 672055299 497 AADCFLTALELEASSP 512
Cdd:COG1729   86 ARATLEELIKKYPDSE 101
TPR_20 pfam14561
Tetratricopeptide repeat;
184-221 7.66e-03

Tetratricopeptide repeat;


Pssm-ID: 434039 [Multi-domain]  Cd Length: 90  Bit Score: 35.95  E-value: 7.66e-03
                          10        20        30
                  ....*....|....*....|....*....|....*...
gi 672055299  184 LQTLERALELAPDDPQIIFYVSLQLALVRQISSAIERL 221
Cdd:pfam14561   8 LAALEARLAADPDDLDARLDLALALHAAGRNEEALELL 45
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 182-498 7.78e-03

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 38.91  E-value: 7.78e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672055299  182 KALQTLERALELAPDDPQIIFYV-SLQLALvRQISSAIERLQEALTVCRDDANALHLLALLFSAQKHHQHALDVINMAIT 260
Cdd:TIGR02917 585 KALAILNEAADAAPDSPEAWLMLgRAQLAA-GDLNKAVSSFKKLLALQPDSALALLLLADAYAVMKNYAKAITSLKRALE 663

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672055299  261 EHPENFNLMFTKVKLEQVLKGPEEALVTCRQMlrlwQALYNFSQLGglekdGSFEGLTVKKQNGIHLTLPDAHDADsgSR 340
Cdd:TIGR02917 664 LKPDNTEAQIGLAQLLLAAKRTESAKKIAKSL----QKQHPKAALG-----FELEGDLYLRQKDYPAAIQAYRKAL--KR 732

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672055299  341 RASSIAASRLEEAMSELTIT-------TSVLKQGPMQLWTTLEQiwlqaAELFMEQRQLKEAGFCIQEAAGLFPTSHSVL 413
Cdd:TIGR02917 733 APSSQNAIKLHRALLASGNTaeavktlEAWLKTHPNDAVLRTAL-----AELYLAQKDYDKAIKHYQTVVKKAPDNAVVL 807

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672055299  414 ymrGRLAEV--KGSFEEAKQLYKEALTVNPDGVCIMHSLGLILSRLGHKSLAQKVLRDAVERQSTHHEAWQGLGEVLQDQ 491
Cdd:TIGR02917 808 ---NNLAWLylELKDPRALEYAERALKLAPNIPAILDTLGWLLVEKGEADRALPLLRKAVNIAPEAAAIRYHLALALLAT 884


                  ....*...
gi 672055299  492 G-HNEAAA 498
Cdd:TIGR02917 885 GrKAEARK 892
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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