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Conserved domains on  [gi|672078692|ref|XP_008769085|]
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olfactomedin-4 isoform X1 [Rattus norvegicus]

Protein Classification

olfactomedin domain-containing protein( domain architecture ID 10490292)

olfactomedin domain-containing protein adopts a five-bladed beta-propeller structure, similar to gliomedin that interacts with neuronal cell adhesion molecules such as neurofascin

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
OLF pfam02191
Olfactomedin-like domain;
191-445 2.13e-113

Olfactomedin-like domain;


:

Pssm-ID: 460482  Cd Length: 246  Bit Score: 333.35  E-value: 2.13e-113
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672078692  191 VVNISAPFVVQLNfqgfNYKYGAWGRDysPQHPERTLYWVAplntDARVLEYYRLYDSLDNLLLYSHSRQYRILY-GQGG 269
Cdd:pfam02191   1 LVSVSKPVTVKLS----GGKYGAWMKD--PLPPSDKIYVTD----RGTSGNTLREYASLDDFKNGSPSKKYKLPYpWQGT 70

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672078692  270 GTVAFNNSLYVNWYNGRNIAKIDLTTNGVTVNQPLPQAAYNNRFSYANVNWQDIDLAVDEQALWAIYATEASTGNIVISK 349
Cdd:pfam02191  71 GHVVYNGSLYYNKYNSRNIVKYDLTTRTVAARRVLPGAGYNNRFPYSWGGHTDIDLAVDENGLWVIYATEENEGNIVVSK 150

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672078692  350 LNDTTLEVISTWVTKQYKPSVSNAFIVCGVLYATRTLNTRTEEIFYYYDTNTQREGSLAITMRKMQERIQSINYHPYDHK 429
Cdd:pfam02191 151 LDPETLEVEQTWNTSYPKRSAGNAFMVCGVLYAVRSVNTRREEIFYAFDTYTGKEEAVSIPFPNRYGKISMLDYNPRDKK 230

                         250
                  ....*....|....*.
gi 672078692  430 LYVYNDGYLLNYDLVF 445
Cdd:pfam02191 231 LYAWDDGYQVTYPVTF 246
 
Name Accession Description Interval E-value
OLF pfam02191
Olfactomedin-like domain;
191-445 2.13e-113

Olfactomedin-like domain;


Pssm-ID: 460482  Cd Length: 246  Bit Score: 333.35  E-value: 2.13e-113
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672078692  191 VVNISAPFVVQLNfqgfNYKYGAWGRDysPQHPERTLYWVAplntDARVLEYYRLYDSLDNLLLYSHSRQYRILY-GQGG 269
Cdd:pfam02191   1 LVSVSKPVTVKLS----GGKYGAWMKD--PLPPSDKIYVTD----RGTSGNTLREYASLDDFKNGSPSKKYKLPYpWQGT 70

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672078692  270 GTVAFNNSLYVNWYNGRNIAKIDLTTNGVTVNQPLPQAAYNNRFSYANVNWQDIDLAVDEQALWAIYATEASTGNIVISK 349
Cdd:pfam02191  71 GHVVYNGSLYYNKYNSRNIVKYDLTTRTVAARRVLPGAGYNNRFPYSWGGHTDIDLAVDENGLWVIYATEENEGNIVVSK 150

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672078692  350 LNDTTLEVISTWVTKQYKPSVSNAFIVCGVLYATRTLNTRTEEIFYYYDTNTQREGSLAITMRKMQERIQSINYHPYDHK 429
Cdd:pfam02191 151 LDPETLEVEQTWNTSYPKRSAGNAFMVCGVLYAVRSVNTRREEIFYAFDTYTGKEEAVSIPFPNRYGKISMLDYNPRDKK 230

                         250
                  ....*....|....*.
gi 672078692  430 LYVYNDGYLLNYDLVF 445
Cdd:pfam02191 231 LYAWDDGYQVTYPVTF 246
OLF smart00284
Olfactomedin-like domains;
189-445 1.02e-80

Olfactomedin-like domains;


Pssm-ID: 128580  Cd Length: 255  Bit Score: 250.13  E-value: 1.02e-80
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672078692   189 GGVVNISAPFVVQLNFQGfnyKYGAWGRDYSPQHPERTLYWVAPLNTdaRVLEYYRLYDSLDNLLLYSHSRQYRILY-GQ 267
Cdd:smart00284   1 GGLAGISKPVTLQTSWKG---KSGAWMKDPLWNTTKKSLYWYMPLNT--RVLRSVREYSSMSDFQMGKNPTDHPLPHaGQ 75

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672078692   268 GGGTVAFNNSLYVNWYNGRNIAKIDLTTNGVTVNQPLPQAAYNNRFSYANVNWQDIDLAVDEQALWAIYATEASTGNIVI 347
Cdd:smart00284  76 GTGVVVYNGSLYFNKFNSHDICRFDLTTETYQKEPLLNGAGYNNRFPYAWGGFSDIDLAVDENGLWVIYATEQNAGKIVI 155

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672078692   348 SKLNDTTLEVISTWVTKQYKPSVSNAFIVCGVLYATRTLNTRTEEIFYYYDTNTQREGSLAITMRKMQERIQSINYHPYD 427
Cdd:smart00284 156 SKLNPATLTIENTWITTYNKRSASNAFMICGILYVTRSLGSKGEKVFYAYDTNTGKEGHLDIPFENMYEYISMLDYNPND 235

                          250
                   ....*....|....*...
gi 672078692   428 HKLYVYNDGYLLNYDLVF 445
Cdd:smart00284 236 RKLYAWNNGHLVHYDIAL 253
 
Name Accession Description Interval E-value
OLF pfam02191
Olfactomedin-like domain;
191-445 2.13e-113

Olfactomedin-like domain;


Pssm-ID: 460482  Cd Length: 246  Bit Score: 333.35  E-value: 2.13e-113
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672078692  191 VVNISAPFVVQLNfqgfNYKYGAWGRDysPQHPERTLYWVAplntDARVLEYYRLYDSLDNLLLYSHSRQYRILY-GQGG 269
Cdd:pfam02191   1 LVSVSKPVTVKLS----GGKYGAWMKD--PLPPSDKIYVTD----RGTSGNTLREYASLDDFKNGSPSKKYKLPYpWQGT 70

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672078692  270 GTVAFNNSLYVNWYNGRNIAKIDLTTNGVTVNQPLPQAAYNNRFSYANVNWQDIDLAVDEQALWAIYATEASTGNIVISK 349
Cdd:pfam02191  71 GHVVYNGSLYYNKYNSRNIVKYDLTTRTVAARRVLPGAGYNNRFPYSWGGHTDIDLAVDENGLWVIYATEENEGNIVVSK 150

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672078692  350 LNDTTLEVISTWVTKQYKPSVSNAFIVCGVLYATRTLNTRTEEIFYYYDTNTQREGSLAITMRKMQERIQSINYHPYDHK 429
Cdd:pfam02191 151 LDPETLEVEQTWNTSYPKRSAGNAFMVCGVLYAVRSVNTRREEIFYAFDTYTGKEEAVSIPFPNRYGKISMLDYNPRDKK 230

                         250
                  ....*....|....*.
gi 672078692  430 LYVYNDGYLLNYDLVF 445
Cdd:pfam02191 231 LYAWDDGYQVTYPVTF 246
OLF smart00284
Olfactomedin-like domains;
189-445 1.02e-80

Olfactomedin-like domains;


Pssm-ID: 128580  Cd Length: 255  Bit Score: 250.13  E-value: 1.02e-80
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672078692   189 GGVVNISAPFVVQLNFQGfnyKYGAWGRDYSPQHPERTLYWVAPLNTdaRVLEYYRLYDSLDNLLLYSHSRQYRILY-GQ 267
Cdd:smart00284   1 GGLAGISKPVTLQTSWKG---KSGAWMKDPLWNTTKKSLYWYMPLNT--RVLRSVREYSSMSDFQMGKNPTDHPLPHaGQ 75

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672078692   268 GGGTVAFNNSLYVNWYNGRNIAKIDLTTNGVTVNQPLPQAAYNNRFSYANVNWQDIDLAVDEQALWAIYATEASTGNIVI 347
Cdd:smart00284  76 GTGVVVYNGSLYFNKFNSHDICRFDLTTETYQKEPLLNGAGYNNRFPYAWGGFSDIDLAVDENGLWVIYATEQNAGKIVI 155

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672078692   348 SKLNDTTLEVISTWVTKQYKPSVSNAFIVCGVLYATRTLNTRTEEIFYYYDTNTQREGSLAITMRKMQERIQSINYHPYD 427
Cdd:smart00284 156 SKLNPATLTIENTWITTYNKRSASNAFMICGILYVTRSLGSKGEKVFYAYDTNTGKEGHLDIPFENMYEYISMLDYNPND 235

                          250
                   ....*....|....*...
gi 672078692   428 HKLYVYNDGYLLNYDLVF 445
Cdd:smart00284 236 RKLYAWNNGHLVHYDIAL 253
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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