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Conserved domains on  [gi|1953292609|ref|XP_038542339|]
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leucine-rich repeat and death domain-containing protein 1 isoform X1 [Canis lupus familiaris]

Protein Classification

leucine-rich repeat domain-containing protein( domain architecture ID 11469232)

leucine-rich repeat (LRR) domain-containing protein may participate in protein-protein interactions

Gene Ontology:  GO:0005515
PubMed:  11751054|7583641|14747988
SCOP:  4003523

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
455-854 1.29e-33

Leucine-rich repeat (LRR) protein [Transcription];


:

Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 134.29  E-value: 1.29e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953292609 455 LNNIISLEFSGNIITDIPIEVKNCKKITKVELSYNKIMYFPVGLCALDSLYYLNFNGNYISEIPVDISFSKQLLNLELNK 534
Cdd:COG4886     3 LLLLSLTLKLLLLLLLELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLL 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953292609 535 NKLLIFSEHLCSLTNLEYLDLGKNQirkippSISNMVSLQVLILCCNKFEVFPIEVCTLENLQVLDLSINQIQNVPSDIC 614
Cdd:COG4886    83 SLLLLGLTDLGDLTNLTELDLSGNE------ELSNLTNLESLDLSGNQLTDLPEELANLTNLKELDLSNNQLTDLPEPLG 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953292609 615 NLKRIQKLNISSNQFMYFPIELCRLQSLEELNISqinGRKLTRLPEELSNLTQLKRLDISDNAIREIPRNIGELRSLVSL 694
Cdd:COG4886   157 NLTNLKSLDLSNNQLTDLPEELGNLTNLKELDLS---NNQITDLPEPLGNLTNLEELDLSGNQLTDLPEPLANLTNLETL 233

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953292609 695 NAYNNQISYLpPSFLCLNDLQQLNLSGNNLTALPiGIHNLFSLKEINFDDNPLLRPPMEICKGKQLYTIVHYLQRADQRD 774
Cdd:COG4886   234 DLSNNQLTDL-PELGNLTNLEELDLSNNQLTDLP-PLANLTNLKTLDLSNNQLTDLKLKELELLLGLNSLLLLLLLLNLL 311

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953292609 775 EKILEKIFIIvANNITITNFKYLCQKLNLAISETDMSTKSPVSLSERVLQALHKWKTESINLSLTTAALRDQLTRALTMI 854
Cdd:COG4886   312 ELLILLLLLT-TLLLLLLLLKGLLVTLTTLALSLSLLALLTLLLLLNLLSLLLTLLLTLGLLGLLEATLLTLALLLLTLL 390
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
113-483 2.45e-30

Leucine-rich repeat (LRR) protein [Transcription];


:

Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 124.66  E-value: 2.45e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953292609 113 SSPLSITEMAAEYQPFIGFLSHETLETTSSQLSEENQKGLGLESDNFTVNLKAKGLQEFPKDiLKSKSVKYLYLDGNQIK 192
Cdd:COG4886     7 SLTLKLLLLLLLELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLL-LSLLLLLLLSLLLLSLL 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953292609 193 NFKGADSGDLLGLEILSLQENgllslpPEIQLFHNLRILNVSHNQISHIPKEISQLGNIRQLFLNNNCIENFPSGLKSLG 272
Cdd:COG4886    86 LLGLTDLGDLTNLTELDLSGN------EELSNLTNLESLDLSGNQLTDLPEELANLTNLKELDLSNNQLTDLPEPLGNLT 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953292609 273 NLEILSLAKNKLRHIPDTLSGLKNLKVLNLEYNQLTIFPKVLCFLPKLISLILTGNLISSLPKEIRelknlekllldhnk 352
Cdd:COG4886   160 NLKSLDLSNNQLTDLPEELGNLTNLKELDLSNNQITDLPEPLGNLTNLEELDLSGNQLTDLPEPLA-------------- 225

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953292609 353 ltflaveifQLLKMKELQLTGNKLEVIShKIENFKELRILILDKNLLKEVPEkISHCVMLEYLSLSCNKLMELP-KNIYK 431
Cdd:COG4886   226 ---------NLTNLETLDLSNNQLTDLP-ELGNLTNLEELDLSNNQLTDLPP-LANLTNLKTLDLSNNQLTDLKlKELEL 294

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1953292609 432 LKNLRKLRVNTNNIVRIPEDISHLNNIISLEFSGNIITDIPIEVKNCKKITK 483
Cdd:COG4886   295 LLGLNSLLLLLLLLNLLELLILLLLLTTLLLLLLLLKGLLVTLTTLALSLSL 346
 
Name Accession Description Interval E-value
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
455-854 1.29e-33

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 134.29  E-value: 1.29e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953292609 455 LNNIISLEFSGNIITDIPIEVKNCKKITKVELSYNKIMYFPVGLCALDSLYYLNFNGNYISEIPVDISFSKQLLNLELNK 534
Cdd:COG4886     3 LLLLSLTLKLLLLLLLELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLL 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953292609 535 NKLLIFSEHLCSLTNLEYLDLGKNQirkippSISNMVSLQVLILCCNKFEVFPIEVCTLENLQVLDLSINQIQNVPSDIC 614
Cdd:COG4886    83 SLLLLGLTDLGDLTNLTELDLSGNE------ELSNLTNLESLDLSGNQLTDLPEELANLTNLKELDLSNNQLTDLPEPLG 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953292609 615 NLKRIQKLNISSNQFMYFPIELCRLQSLEELNISqinGRKLTRLPEELSNLTQLKRLDISDNAIREIPRNIGELRSLVSL 694
Cdd:COG4886   157 NLTNLKSLDLSNNQLTDLPEELGNLTNLKELDLS---NNQITDLPEPLGNLTNLEELDLSGNQLTDLPEPLANLTNLETL 233

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953292609 695 NAYNNQISYLpPSFLCLNDLQQLNLSGNNLTALPiGIHNLFSLKEINFDDNPLLRPPMEICKGKQLYTIVHYLQRADQRD 774
Cdd:COG4886   234 DLSNNQLTDL-PELGNLTNLEELDLSNNQLTDLP-PLANLTNLKTLDLSNNQLTDLKLKELELLLGLNSLLLLLLLLNLL 311

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953292609 775 EKILEKIFIIvANNITITNFKYLCQKLNLAISETDMSTKSPVSLSERVLQALHKWKTESINLSLTTAALRDQLTRALTMI 854
Cdd:COG4886   312 ELLILLLLLT-TLLLLLLLLKGLLVTLTTLALSLSLLALLTLLLLLNLLSLLLTLLLTLGLLGLLEATLLTLALLLLTLL 390
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 228-712 5.22e-32

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 134.59  E-value: 5.22e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953292609 228 LRILNVSHNQIS-HIPKEISQLG-NIRQLFL-NNNCIENFPSGlkSLGNLEILSLAKNKLR-HIPDTLSGLKNLKVLNLE 303
Cdd:PLN00113   95 IQTINLSNNQLSgPIPDDIFTTSsSLRYLNLsNNNFTGSIPRG--SIPNLETLDLSNNMLSgEIPNDIGSFSSLKVLDLG 172

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953292609 304 YNQLT-IFPKVLCFLPKLISLILTGN-LISSLPKEIRELKNLEKLLLDHNKLTF-LAVEIFQLLKMKELQLTGNKLE-VI 379
Cdd:PLN00113  173 GNVLVgKIPNSLTNLTSLEFLTLASNqLVGQIPRELGQMKSLKWIYLGYNNLSGeIPYEIGGLTSLNHLDLVYNNLTgPI 252

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953292609 380 SHKIENFKELRILILDKNLLK-EVPEKISHCVMLEYLSLSCNKLM-ELPKNIYKLKNLRKLRVNTNNIV-RIPEDISHLN 456
Cdd:PLN00113  253 PSSLGNLKNLQYLFLYQNKLSgPIPPSIFSLQKLISLDLSDNSLSgEIPELVIQLQNLEILHLFSNNFTgKIPVALTSLP 332

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953292609 457 NIISLE-FSGNIITDIPIEVKNCKKITKVELSYNKIM-YFPVGLCALDSLYYLNFNGNYI-SEIPVDISFSKQLLNLELN 533
Cdd:PLN00113  333 RLQVLQlWSNKFSGEIPKNLGKHNNLTVLDLSTNNLTgEIPEGLCSSGNLFKLILFSNSLeGEIPKSLGACRSLRRVRLQ 412

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953292609 534 KNKLL-IFSEHLCSLTNLEYLDLGKNQIR-KIPPSISNMVSLQVLILCCNKFEVFPIEVCTLENLQVLDLSINQIQN-VP 610
Cdd:PLN00113  413 DNSFSgELPSEFTKLPLVYFLDISNNNLQgRINSRKWDMPSLQMLSLARNKFFGGLPDSFGSKRLENLDLSRNQFSGaVP 492

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953292609 611 SDICNLKRIQKLNISSNQFM-YFPIELCRLQSLEELNISQingRKLT-RLPEELSNLTQLKRLDISDNAIR-EIPRNIGE 687
Cdd:PLN00113  493 RKLGSLSELMQLKLSENKLSgEIPDELSSCKKLVSLDLSH---NQLSgQIPASFSEMPVLSQLDLSQNQLSgEIPKNLGN 569

                         490       500
                  ....*....|....*....|....*...
gi 1953292609 688 LRSLVSLNAYNNQI-SYLPPS--FLCLN 712
Cdd:PLN00113  570 VESLVQVNISHNHLhGSLPSTgaFLAIN 597
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
113-483 2.45e-30

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 124.66  E-value: 2.45e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953292609 113 SSPLSITEMAAEYQPFIGFLSHETLETTSSQLSEENQKGLGLESDNFTVNLKAKGLQEFPKDiLKSKSVKYLYLDGNQIK 192
Cdd:COG4886     7 SLTLKLLLLLLLELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLL-LSLLLLLLLSLLLLSLL 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953292609 193 NFKGADSGDLLGLEILSLQENgllslpPEIQLFHNLRILNVSHNQISHIPKEISQLGNIRQLFLNNNCIENFPSGLKSLG 272
Cdd:COG4886    86 LLGLTDLGDLTNLTELDLSGN------EELSNLTNLESLDLSGNQLTDLPEELANLTNLKELDLSNNQLTDLPEPLGNLT 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953292609 273 NLEILSLAKNKLRHIPDTLSGLKNLKVLNLEYNQLTIFPKVLCFLPKLISLILTGNLISSLPKEIRelknlekllldhnk 352
Cdd:COG4886   160 NLKSLDLSNNQLTDLPEELGNLTNLKELDLSNNQITDLPEPLGNLTNLEELDLSGNQLTDLPEPLA-------------- 225

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953292609 353 ltflaveifQLLKMKELQLTGNKLEVIShKIENFKELRILILDKNLLKEVPEkISHCVMLEYLSLSCNKLMELP-KNIYK 431
Cdd:COG4886   226 ---------NLTNLETLDLSNNQLTDLP-ELGNLTNLEELDLSNNQLTDLPP-LANLTNLKTLDLSNNQLTDLKlKELEL 294

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1953292609 432 LKNLRKLRVNTNNIVRIPEDISHLNNIISLEFSGNIITDIPIEVKNCKKITK 483
Cdd:COG4886   295 LLGLNSLLLLLLLLNLLELLILLLLLTTLLLLLLLLKGLLVTLTTLALSLSL 346
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 161-335 5.72e-11

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 63.27  E-value: 5.72e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953292609 161 VNLKAKGLQEFPkDILKSKSVKYLYLDGNQIKNFKGADSgdLLGLEILSLQENGLLSLPPeIQLFHNLRILNVSHNQISH 240
Cdd:cd21340     7 LYLNDKNITKID-NLSLCKNLKVLYLYDNKITKIENLEF--LTNLTHLYLQNNQIEKIEN-LENLVNLKKLYLGGNRISV 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953292609 241 IpKEISQLGNIRQLFLNNNCIEN-----F-PSGLKSLGN-LEILSLAKNKLRHIPDtLSGLKNLKVLNLEYNQLTIFPKV 313
Cdd:cd21340    83 V-EGLENLTNLEELHIENQRLPPgekltFdPRSLAALSNsLRVLNISGNNIDSLEP-LAPLRNLEQLDASNNQISDLEEL 160

                         170       180
                  ....*....|....*....|....*
gi 1953292609 314 LCFL---PKLISLILTGNLISSLPK 335
Cdd:cd21340   161 LDLLsswPSLRELDLTGNPVCKKPK 185
PRK15370 PRK15370
type III secretion system effector E3 ubiquitin transferase SlrP;
160-337 6.39e-11

type III secretion system effector E3 ubiquitin transferase SlrP;


Pssm-ID: 185268 [Multi-domain]  Cd Length: 754  Bit Score: 66.26  E-value: 6.39e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953292609 160 TVNLKAKGLQEFPKDIlkSKSVKYLYLDGNQIKNFKGA--DSgdllgLEILSLQENGLLSLPPEIQ-------LFHN--- 227
Cdd:PRK15370  203 TLILDNNELKSLPENL--QGNIKTLYANSNQLTSIPATlpDT-----IQEMELSINRITELPERLPsalqsldLFHNkis 275

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953292609 228 ---------LRILNVSHNQISHIPKEISQlgNIRQLFLNNNCIENFPSGLKSlgNLEILSLAKNKLRHIPDTLSglKNLK 298
Cdd:PRK15370  276 clpenlpeeLRYLSVYDNSIRTLPAHLPS--GITHLNVQSNSLTALPETLPP--GLKTLEAGENALTSLPASLP--PELQ 349

                         170       180       190
                  ....*....|....*....|....*....|....*....
gi 1953292609 299 VLNLEYNQLTIFPKVLCflPKLISLILTGNLISSLPKEI 337
Cdd:PRK15370  350 VLDVSKNQITVLPETLP--PTITTLDVSRNALTNLPENL 386
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 501-751 6.71e-11

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 62.88  E-value: 6.71e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953292609 501 LDSLYYLNFNGNYISEIPvDISFSKQLLNLELNKNKL-LIfsEHLCSLTNLEYLDLGKNQIRKIPPsISNMVSLQVLILC 579
Cdd:cd21340     1 LKRITHLYLNDKNITKID-NLSLCKNLKVLYLYDNKItKI--ENLEFLTNLTHLYLQNNQIEKIEN-LENLVNLKKLYLG 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953292609 580 CNKfevfpieVCTLENLQvldlsinqiqnvpsdicnlkriqklnissnqfmyfpielcRLQSLEELNISQIN---GRKLT 656
Cdd:cd21340    77 GNR-------ISVVEGLE----------------------------------------NLTNLEELHIENQRlppGEKLT 109

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953292609 657 RLPEELSNLTQ-LKRLDISDNAIREIpRNIGELRSLVSLNAYNNQISylppsflCLNDLQQLnlsgnnltalpigIHNLF 735
Cdd:cd21340   110 FDPRSLAALSNsLRVLNISGNNIDSL-EPLAPLRNLEQLDASNNQIS-------DLEELLDL-------------LSSWP 168

                         250
                  ....*....|....*.
gi 1953292609 736 SLKEINFDDNPLLRPP 751
Cdd:cd21340   169 SLRELDLTGNPVCKKP 184
LRR_8 pfam13855
Leucine rich repeat;
273-330 7.62e-08

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 49.83  E-value: 7.62e-08
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953292609 273 NLEILSLAKNKLRHI-PDTLSGLKNLKVLNLEYNQLT-IFPKVLCFLPKLISLILTGNLI 330
Cdd:pfam13855   2 NLRSLDLSNNRLTSLdDGAFKGLSNLKVLDLSNNLLTtLSPGAFSGLPSLRYLDLSGNRL 61
LRR_8 pfam13855
Leucine rich repeat;
666-724 8.31e-05

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 40.97  E-value: 8.31e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1953292609 666 TQLKRLDISDNAIREI-PRNIGELRSLVSLNAYNNQISYLPP-SFLCLNDLQQLNLSGNNL 724
Cdd:pfam13855   1 PNLRSLDLSNNRLTSLdDGAFKGLSNLKVLDLSNNLLTTLSPgAFSGLPSLRYLDLSGNRL 61
DEATH smart00005
DEATH domain, found in proteins involved in cell death (apoptosis); Alpha-helical domain ...
 778-864 7.56e-03

DEATH domain, found in proteins involved in cell death (apoptosis); Alpha-helical domain present in a variety of proteins with apoptotic functions. Some (but not all) of these domains form homotypic and heterotypic dimers.


Pssm-ID: 214467 [Multi-domain]  Cd Length: 88  Bit Score: 36.62  E-value: 7.56e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953292609  778 LEKIFIIVANNITITNFKYLCQKLNLaiSETDM---STKSPVSLSERVLQALHKWKT-ESINLSLttaalrDQLTRALTM 853
Cdd:smart00005   4 TRQKLAKLLDHPLGLDWRELARKLGL--SEADIdqiRTEAPRDLAEQSVQLLRLWEQrEGKNATL------GTLLEALRK 75

                           90
                   ....*....|.
gi 1953292609  854 IGAYEIMDKIT 864
Cdd:smart00005  76 MGRDDAVELLR 86
 
Name Accession Description Interval E-value
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
455-854 1.29e-33

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 134.29  E-value: 1.29e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953292609 455 LNNIISLEFSGNIITDIPIEVKNCKKITKVELSYNKIMYFPVGLCALDSLYYLNFNGNYISEIPVDISFSKQLLNLELNK 534
Cdd:COG4886     3 LLLLSLTLKLLLLLLLELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLL 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953292609 535 NKLLIFSEHLCSLTNLEYLDLGKNQirkippSISNMVSLQVLILCCNKFEVFPIEVCTLENLQVLDLSINQIQNVPSDIC 614
Cdd:COG4886    83 SLLLLGLTDLGDLTNLTELDLSGNE------ELSNLTNLESLDLSGNQLTDLPEELANLTNLKELDLSNNQLTDLPEPLG 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953292609 615 NLKRIQKLNISSNQFMYFPIELCRLQSLEELNISqinGRKLTRLPEELSNLTQLKRLDISDNAIREIPRNIGELRSLVSL 694
Cdd:COG4886   157 NLTNLKSLDLSNNQLTDLPEELGNLTNLKELDLS---NNQITDLPEPLGNLTNLEELDLSGNQLTDLPEPLANLTNLETL 233

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953292609 695 NAYNNQISYLpPSFLCLNDLQQLNLSGNNLTALPiGIHNLFSLKEINFDDNPLLRPPMEICKGKQLYTIVHYLQRADQRD 774
Cdd:COG4886   234 DLSNNQLTDL-PELGNLTNLEELDLSNNQLTDLP-PLANLTNLKTLDLSNNQLTDLKLKELELLLGLNSLLLLLLLLNLL 311

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953292609 775 EKILEKIFIIvANNITITNFKYLCQKLNLAISETDMSTKSPVSLSERVLQALHKWKTESINLSLTTAALRDQLTRALTMI 854
Cdd:COG4886   312 ELLILLLLLT-TLLLLLLLLKGLLVTLTTLALSLSLLALLTLLLLLNLLSLLLTLLLTLGLLGLLEATLLTLALLLLTLL 390
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
385-748 3.90e-32

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 130.05  E-value: 3.90e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953292609 385 NFKELRILILDKNLLKEVPEKISHCVMLEYLSLSCNKLMELPKNIYKLKNLRKLRVNTNNIVRIPEDISHLNNIISLEFS 464
Cdd:COG4886     2 LLLLLSLTLKLLLLLLLELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLL 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953292609 465 GNIITDIPIEVKNCKKITKVELSYNKimyfpvGLCALDSLYYLNFNGNYISEIPVDISFSKQLLNLELNKNKLLIFSEHL 544
Cdd:COG4886    82 LSLLLLGLTDLGDLTNLTELDLSGNE------ELSNLTNLESLDLSGNQLTDLPEELANLTNLKELDLSNNQLTDLPEPL 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953292609 545 CSLTNLEYLDLGKNQIRKIPPSISNMVSLQVLILCCNKFEVFPIEVCTLENLQVLDLSINQIQNVPSDICNLKRIQKLNI 624
Cdd:COG4886   156 GNLTNLKSLDLSNNQLTDLPEELGNLTNLKELDLSNNQITDLPEPLGNLTNLEELDLSGNQLTDLPEPLANLTNLETLDL 235

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953292609 625 SSNQFMYFPiELCRLQSLEELNISqinGRKLTRLPeELSNLTQLKRLDISDNAIREIPRNIGELRSLVSLNAYNNQISYL 704
Cdd:COG4886   236 SNNQLTDLP-ELGNLTNLEELDLS---NNQLTDLP-PLANLTNLKTLDLSNNQLTDLKLKELELLLGLNSLLLLLLLLNL 310

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....
gi 1953292609 705 PPSFLCLNDLQQLNLSGNNLTALPIGIHNLFSLKEINFDDNPLL 748
Cdd:COG4886   311 LELLILLLLLTTLLLLLLLLKGLLVTLTTLALSLSLLALLTLLL 354
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 228-712 5.22e-32

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 134.59  E-value: 5.22e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953292609 228 LRILNVSHNQIS-HIPKEISQLG-NIRQLFL-NNNCIENFPSGlkSLGNLEILSLAKNKLR-HIPDTLSGLKNLKVLNLE 303
Cdd:PLN00113   95 IQTINLSNNQLSgPIPDDIFTTSsSLRYLNLsNNNFTGSIPRG--SIPNLETLDLSNNMLSgEIPNDIGSFSSLKVLDLG 172

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953292609 304 YNQLT-IFPKVLCFLPKLISLILTGN-LISSLPKEIRELKNLEKLLLDHNKLTF-LAVEIFQLLKMKELQLTGNKLE-VI 379
Cdd:PLN00113  173 GNVLVgKIPNSLTNLTSLEFLTLASNqLVGQIPRELGQMKSLKWIYLGYNNLSGeIPYEIGGLTSLNHLDLVYNNLTgPI 252

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953292609 380 SHKIENFKELRILILDKNLLK-EVPEKISHCVMLEYLSLSCNKLM-ELPKNIYKLKNLRKLRVNTNNIV-RIPEDISHLN 456
Cdd:PLN00113  253 PSSLGNLKNLQYLFLYQNKLSgPIPPSIFSLQKLISLDLSDNSLSgEIPELVIQLQNLEILHLFSNNFTgKIPVALTSLP 332

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953292609 457 NIISLE-FSGNIITDIPIEVKNCKKITKVELSYNKIM-YFPVGLCALDSLYYLNFNGNYI-SEIPVDISFSKQLLNLELN 533
Cdd:PLN00113  333 RLQVLQlWSNKFSGEIPKNLGKHNNLTVLDLSTNNLTgEIPEGLCSSGNLFKLILFSNSLeGEIPKSLGACRSLRRVRLQ 412

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953292609 534 KNKLL-IFSEHLCSLTNLEYLDLGKNQIR-KIPPSISNMVSLQVLILCCNKFEVFPIEVCTLENLQVLDLSINQIQN-VP 610
Cdd:PLN00113  413 DNSFSgELPSEFTKLPLVYFLDISNNNLQgRINSRKWDMPSLQMLSLARNKFFGGLPDSFGSKRLENLDLSRNQFSGaVP 492

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953292609 611 SDICNLKRIQKLNISSNQFM-YFPIELCRLQSLEELNISQingRKLT-RLPEELSNLTQLKRLDISDNAIR-EIPRNIGE 687
Cdd:PLN00113  493 RKLGSLSELMQLKLSENKLSgEIPDELSSCKKLVSLDLSH---NQLSgQIPASFSEMPVLSQLDLSQNQLSgEIPKNLGN 569

                         490       500
                  ....*....|....*....|....*...
gi 1953292609 688 LRSLVSLNAYNNQI-SYLPPS--FLCLN 712
Cdd:PLN00113  570 VESLVQVNISHNHLhGSLPSTgaFLAIN 597
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
113-483 2.45e-30

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 124.66  E-value: 2.45e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953292609 113 SSPLSITEMAAEYQPFIGFLSHETLETTSSQLSEENQKGLGLESDNFTVNLKAKGLQEFPKDiLKSKSVKYLYLDGNQIK 192
Cdd:COG4886     7 SLTLKLLLLLLLELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLL-LSLLLLLLLSLLLLSLL 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953292609 193 NFKGADSGDLLGLEILSLQENgllslpPEIQLFHNLRILNVSHNQISHIPKEISQLGNIRQLFLNNNCIENFPSGLKSLG 272
Cdd:COG4886    86 LLGLTDLGDLTNLTELDLSGN------EELSNLTNLESLDLSGNQLTDLPEELANLTNLKELDLSNNQLTDLPEPLGNLT 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953292609 273 NLEILSLAKNKLRHIPDTLSGLKNLKVLNLEYNQLTIFPKVLCFLPKLISLILTGNLISSLPKEIRelknlekllldhnk 352
Cdd:COG4886   160 NLKSLDLSNNQLTDLPEELGNLTNLKELDLSNNQITDLPEPLGNLTNLEELDLSGNQLTDLPEPLA-------------- 225

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953292609 353 ltflaveifQLLKMKELQLTGNKLEVIShKIENFKELRILILDKNLLKEVPEkISHCVMLEYLSLSCNKLMELP-KNIYK 431
Cdd:COG4886   226 ---------NLTNLETLDLSNNQLTDLP-ELGNLTNLEELDLSNNQLTDLPP-LANLTNLKTLDLSNNQLTDLKlKELEL 294

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1953292609 432 LKNLRKLRVNTNNIVRIPEDISHLNNIISLEFSGNIITDIPIEVKNCKKITK 483
Cdd:COG4886   295 LLGLNSLLLLLLLLNLLELLILLLLLTTLLLLLLLLKGLLVTLTTLALSLSL 346
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
353-737 4.24e-30

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 123.89  E-value: 4.24e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953292609 353 LTFLAVEIFQLLKMKELQLTGNKLEVISHKIENFKELRILILDKNLLKEVPEKISHCVMLEYLSLSCNKLMELPKNIYKL 432
Cdd:COG4886    16 LLLELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSLLLLGLTDLGDL 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953292609 433 KNLRKLRVNTNNivripeDISHLNNIISLEFSGNIITDIPIEVKNCKKITKVELSYNKIMYFPVGLCALDSLYYLNFNGN 512
Cdd:COG4886    96 TNLTELDLSGNE------ELSNLTNLESLDLSGNQLTDLPEELANLTNLKELDLSNNQLTDLPEPLGNLTNLKSLDLSNN 169

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953292609 513 YISEIPVDISFSKQLLNLELNKNKLLIFSEHLCSLTNLEYLDLGKNQIRKIPPSISNMVSLQVLILCCNKFEVFPiEVCT 592
Cdd:COG4886   170 QLTDLPEELGNLTNLKELDLSNNQITDLPEPLGNLTNLEELDLSGNQLTDLPEPLANLTNLETLDLSNNQLTDLP-ELGN 248

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953292609 593 LENLQVLDLSINQIQNVPsDICNLKRIQKLNISSNQfmyfpIELCRLQSLEELNISQINGRKLTRLPEELSNLTQLKRLD 672
Cdd:COG4886   249 LTNLEELDLSNNQLTDLP-PLANLTNLKTLDLSNNQ-----LTDLKLKELELLLGLNSLLLLLLLLNLLELLILLLLLTT 322

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1953292609 673 ISDNAIREIPRNIGELRSLVSLNAYNNQISYLPPSFLCLNDLQQLNLSGNNLTALPIGIHNLFSL 737
Cdd:COG4886   323 LLLLLLLLKGLLVTLTTLALSLSLLALLTLLLLLNLLSLLLTLLLTLGLLGLLEATLLTLALLLL 387
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
154-598 3.09e-28

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 118.50  E-value: 3.09e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953292609 154 LESDNFTVNLKAKGLQEFPKDILKSKSVKYLYLDGNQIKNFKGADSGDLLGLEILSLQENGLLSLPPEIQLFHNLRILNV 233
Cdd:COG4886     1 LLLLLLSLTLKLLLLLLLELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953292609 234 SHNQISHIPKEISQLGNIRQLFLNNNcienfpSGLKSLGNLEILSLAKNKLRHIPDTLSGLKNLKVLNLEYNQLTIFPKV 313
Cdd:COG4886    81 LLSLLLLGLTDLGDLTNLTELDLSGN------EELSNLTNLESLDLSGNQLTDLPEELANLTNLKELDLSNNQLTDLPEP 154

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953292609 314 LCFLPKLISLILTGNLISSLPKEIrelknlekllldhnkltflaveiFQLLKMKELQLTGNKLEVISHKIENFKELRILI 393
Cdd:COG4886   155 LGNLTNLKSLDLSNNQLTDLPEEL-----------------------GNLTNLKELDLSNNQITDLPEPLGNLTNLEELD 211

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953292609 394 LDKNLLKEVPEKISHCVMLEYLSLSCNKLMELPkNIYKLKNLRKLRVNTNNIVRIPEdISHLNNIISLEFSGNIITDIPI 473
Cdd:COG4886   212 LSGNQLTDLPEPLANLTNLETLDLSNNQLTDLP-ELGNLTNLEELDLSNNQLTDLPP-LANLTNLKTLDLSNNQLTDLKL 289

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953292609 474 EVKNCKKITKVELSYNKIMYFPVGLCALDSLYYLNFNGNYISEIPVDISFSKQLLNLELNKNKLLIFSEHLCSLTNLEYL 553
Cdd:COG4886   290 KELELLLGLNSLLLLLLLLNLLELLILLLLLTTLLLLLLLLKGLLVTLTTLALSLSLLALLTLLLLLNLLSLLLTLLLTL 369

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|....*
gi 1953292609 554 DLGKNQIRKIPPSISNMVSLQVLILCCNKFEVFPIEVCTLENLQV 598
Cdd:COG4886   370 GLLGLLEATLLTLALLLLTLLLLLLTTTAGVLLLTLALLDAVNTE 414
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
307-728 5.80e-28

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 117.73  E-value: 5.80e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953292609 307 LTIFPKVLCFLPKLISLILTGNLISSLPKEIRELKNLEKLLLDHNKLTFLAVEIFQLLKMKELQLTGNKLEVISHKIENF 386
Cdd:COG4886    16 LLLELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSLLLLGLTDLGDL 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953292609 387 KELRILILDKNllkevpEKISHCVMLEYLSLSCNKLMELPKNIYKLKNLRKLRVNTNNIVRIPEDISHLNNIISLEFSGN 466
Cdd:COG4886    96 TNLTELDLSGN------EELSNLTNLESLDLSGNQLTDLPEELANLTNLKELDLSNNQLTDLPEPLGNLTNLKSLDLSNN 169

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953292609 467 IITDIPIEVKNCKKITKVELSYNKIMYFPVGLCALDSLYYLNFNGNYISEIPVDISfskqllnlelnknkllifsehlcS 546
Cdd:COG4886   170 QLTDLPEELGNLTNLKELDLSNNQITDLPEPLGNLTNLEELDLSGNQLTDLPEPLA-----------------------N 226

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953292609 547 LTNLEYLDLGKNQIRKIpPSISNMVSLQVLILCCNKFEVFPiEVCTLENLQVLDLSINQIQNVPSDICNLKRIQKLNISS 626
Cdd:COG4886   227 LTNLETLDLSNNQLTDL-PELGNLTNLEELDLSNNQLTDLP-PLANLTNLKTLDLSNNQLTDLKLKELELLLGLNSLLLL 304

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953292609 627 NQFMYFPIELCRLQSLEELNISQINGRKLTRLPEELSNLTQLKRLDISDNAIREIPRNIGELRSLVSLNAYNNQISYLPP 706
Cdd:COG4886   305 LLLLNLLELLILLLLLTTLLLLLLLLKGLLVTLTTLALSLSLLALLTLLLLLNLLSLLLTLLLTLGLLGLLEATLLTLAL 384

                         410       420
                  ....*....|....*....|..
gi 1953292609 707 SFLCLNDLQQLNLSGNNLTALP 728
Cdd:COG4886   385 LLLTLLLLLLTTTAGVLLLTLA 406
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
256-667 4.57e-27

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 115.03  E-value: 4.57e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953292609 256 LNNNCIENFPSGLKSLGNLEILSLAKNKLRHIPDTLSGLKNLKVLNLEYNQLTIFPKVLCFLPKLISLILTGNLISSLPK 335
Cdd:COG4886     1 LLLLLLSLTLKLLLLLLLELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953292609 336 EIRELKNLEKLLLDHNKLTFLAV----EIFQLLKMKELQLTGNKLEVISHKIENFKELRILILDKNLLKEVPEKISHCVM 411
Cdd:COG4886    81 LLSLLLLGLTDLGDLTNLTELDLsgneELSNLTNLESLDLSGNQLTDLPEELANLTNLKELDLSNNQLTDLPEPLGNLTN 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953292609 412 LEYLSLSCNKLMELPKNIYKLKNLRKLRVNTNNIVRIPEDISHLNNIISLEFSGNIITDIPIEVKNCKKITKVELSYNKI 491
Cdd:COG4886   161 LKSLDLSNNQLTDLPEELGNLTNLKELDLSNNQITDLPEPLGNLTNLEELDLSGNQLTDLPEPLANLTNLETLDLSNNQL 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953292609 492 MYFPvGLCALDSLYYLNFNGNYISEIPVDISFsKQLLNLELNKNKLLIFSEHLCSLTNLEYLDLGKNQIRKIPPSISNMV 571
Cdd:COG4886   241 TDLP-ELGNLTNLEELDLSNNQLTDLPPLANL-TNLKTLDLSNNQLTDLKLKELELLLGLNSLLLLLLLLNLLELLILLL 318

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953292609 572 SLQVLILCCNKFEVFPIEVCTLENLQVLDLSINQIQNVPSDICNLKRIQKLNISSNQFMYFPIELCRLQSLEELNISQIN 651
Cdd:COG4886   319 LLTTLLLLLLLLKGLLVTLTTLALSLSLLALLTLLLLLNLLSLLLTLLLTLGLLGLLEATLLTLALLLLTLLLLLLTTTA 398

                         410
                  ....*....|....*.
gi 1953292609 652 GRKLTRLPEELSNLTQ 667
Cdd:COG4886   399 GVLLLTLALLDAVNTE 414
PRK15370 PRK15370
type III secretion system effector E3 ubiquitin transferase SlrP;
384-697 1.83e-16

type III secretion system effector E3 ubiquitin transferase SlrP;


Pssm-ID: 185268 [Multi-domain]  Cd Length: 754  Bit Score: 83.98  E-value: 1.83e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953292609 384 ENFKELRILILDKNLLKE-VPEKIShcvmleYLSLSCNKLMELPKNIYKlkNLRKLRVNTNNIVRIPEDIShlNNIISLE 462
Cdd:PRK15370  178 NNKTELRLKILGLTTIPAcIPEQIT------TLILDNNELKSLPENLQG--NIKTLYANSNQLTSIPATLP--DTIQEME 247

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953292609 463 FSGNIITDIPIEVKNCkkITKVELSYNKIMYFPVGLCalDSLYYLNFNGNYISEIPVDISFSkqLLNLELNKNKLLIFSE 542
Cdd:PRK15370  248 LSINRITELPERLPSA--LQSLDLFHNKISCLPENLP--EELRYLSVYDNSIRTLPAHLPSG--ITHLNVQSNSLTALPE 321

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953292609 543 HLCslTNLEYLDLGKNQIRKIPPSIsnmvslqvlilccnkfevfPIEvctlenLQVLDLSINQIQNVPSDICnlKRIQKL 622
Cdd:PRK15370  322 TLP--PGLKTLEAGENALTSLPASL-------------------PPE------LQVLDVSKNQITVLPETLP--PTITTL 372

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1953292609 623 NISSNQFMYFPIELCrlqslEELNISQINGRKLTRLPEELSNL----TQLKRLDISDNAIREipRNIGELRSLVSLNAY 697
Cdd:PRK15370  373 DVSRNALTNLPENLP-----AALQIMQASRNNLVRLPESLPHFrgegPQPTRIIVEYNPFSE--RTIQNMQRLMSSVGY 444
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 458-764 2.11e-14

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 77.58  E-value: 2.11e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953292609 458 IISLEFSG-NIITDIPIEVKNCKKITKVELSYNKIMY-FPVGLCAL-DSLYYLNF-NGNYISEIPVDISFSKQLLNLELN 533
Cdd:PLN00113   71 VVSIDLSGkNISGKISSAIFRLPYIQTINLSNNQLSGpIPDDIFTTsSSLRYLNLsNNNFTGSIPRGSIPNLETLDLSNN 150

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953292609 534 KNKLLIFSEhLCSLTNLEYLDLGKNQIR-KIPPSISNMVSLQVLILCCNKFE-VFPIEVCTLENLQVLDLSINQIQ-NVP 610
Cdd:PLN00113  151 MLSGEIPND-IGSFSSLKVLDLGGNVLVgKIPNSLTNLTSLEFLTLASNQLVgQIPRELGQMKSLKWIYLGYNNLSgEIP 229

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953292609 611 SDICNLKRIQKLNISSNQFM-YFPIELCRLQSLEELNISQingRKLT-RLPEELSNLTQLKRLDISDNAIR-EIPRNIGE 687
Cdd:PLN00113  230 YEIGGLTSLNHLDLVYNNLTgPIPSSLGNLKNLQYLFLYQ---NKLSgPIPPSIFSLQKLISLDLSDNSLSgEIPELVIQ 306

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953292609 688 LRSLVSLNAYNNQISYLPPSFLC-LNDLQQLNLSGNNLTA-LP--IGIHNlfSLKEINFDDNPLL-RPPMEICKGKQLYT 762
Cdd:PLN00113  307 LQNLEILHLFSNNFTGKIPVALTsLPRLQVLQLWSNKFSGeIPknLGKHN--NLTVLDLSTNNLTgEIPEGLCSSGNLFK 384


                  ..
gi 1953292609 763 IV 764
Cdd:PLN00113  385 LI 386
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 161-335 5.72e-11

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 63.27  E-value: 5.72e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953292609 161 VNLKAKGLQEFPkDILKSKSVKYLYLDGNQIKNFKGADSgdLLGLEILSLQENGLLSLPPeIQLFHNLRILNVSHNQISH 240
Cdd:cd21340     7 LYLNDKNITKID-NLSLCKNLKVLYLYDNKITKIENLEF--LTNLTHLYLQNNQIEKIEN-LENLVNLKKLYLGGNRISV 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953292609 241 IpKEISQLGNIRQLFLNNNCIEN-----F-PSGLKSLGN-LEILSLAKNKLRHIPDtLSGLKNLKVLNLEYNQLTIFPKV 313
Cdd:cd21340    83 V-EGLENLTNLEELHIENQRLPPgekltFdPRSLAALSNsLRVLNISGNNIDSLEP-LAPLRNLEQLDASNNQISDLEEL 160

                         170       180
                  ....*....|....*....|....*
gi 1953292609 314 LCFL---PKLISLILTGNLISSLPK 335
Cdd:cd21340   161 LDLLsswPSLRELDLTGNPVCKKPK 185
PRK15370 PRK15370
type III secretion system effector E3 ubiquitin transferase SlrP;
160-337 6.39e-11

type III secretion system effector E3 ubiquitin transferase SlrP;


Pssm-ID: 185268 [Multi-domain]  Cd Length: 754  Bit Score: 66.26  E-value: 6.39e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953292609 160 TVNLKAKGLQEFPKDIlkSKSVKYLYLDGNQIKNFKGA--DSgdllgLEILSLQENGLLSLPPEIQ-------LFHN--- 227
Cdd:PRK15370  203 TLILDNNELKSLPENL--QGNIKTLYANSNQLTSIPATlpDT-----IQEMELSINRITELPERLPsalqsldLFHNkis 275

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953292609 228 ---------LRILNVSHNQISHIPKEISQlgNIRQLFLNNNCIENFPSGLKSlgNLEILSLAKNKLRHIPDTLSglKNLK 298
Cdd:PRK15370  276 clpenlpeeLRYLSVYDNSIRTLPAHLPS--GITHLNVQSNSLTALPETLPP--GLKTLEAGENALTSLPASLP--PELQ 349

                         170       180       190
                  ....*....|....*....|....*....|....*....
gi 1953292609 299 VLNLEYNQLTIFPKVLCflPKLISLILTGNLISSLPKEI 337
Cdd:PRK15370  350 VLDVSKNQITVLPETLP--PTITTLDVSRNALTNLPENL 386
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 501-751 6.71e-11

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 62.88  E-value: 6.71e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953292609 501 LDSLYYLNFNGNYISEIPvDISFSKQLLNLELNKNKL-LIfsEHLCSLTNLEYLDLGKNQIRKIPPsISNMVSLQVLILC 579
Cdd:cd21340     1 LKRITHLYLNDKNITKID-NLSLCKNLKVLYLYDNKItKI--ENLEFLTNLTHLYLQNNQIEKIEN-LENLVNLKKLYLG 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953292609 580 CNKfevfpieVCTLENLQvldlsinqiqnvpsdicnlkriqklnissnqfmyfpielcRLQSLEELNISQIN---GRKLT 656
Cdd:cd21340    77 GNR-------ISVVEGLE----------------------------------------NLTNLEELHIENQRlppGEKLT 109

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953292609 657 RLPEELSNLTQ-LKRLDISDNAIREIpRNIGELRSLVSLNAYNNQISylppsflCLNDLQQLnlsgnnltalpigIHNLF 735
Cdd:cd21340   110 FDPRSLAALSNsLRVLNISGNNIDSL-EPLAPLRNLEQLDASNNQIS-------DLEELLDL-------------LSSWP 168

                         250
                  ....*....|....*.
gi 1953292609 736 SLKEINFDDNPLLRPP 751
Cdd:cd21340   169 SLRELDLTGNPVCKKP 184
PRK15370 PRK15370
type III secretion system effector E3 ubiquitin transferase SlrP;
514-751 3.27e-10

type III secretion system effector E3 ubiquitin transferase SlrP;


Pssm-ID: 185268 [Multi-domain]  Cd Length: 754  Bit Score: 63.95  E-value: 3.27e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953292609 514 ISEIPVDISfsKQLLNLELNKNKLLIFSEHLCSltNLEYLDLGKNQIRKIPpsisnmvslqvlilccnkfEVFPievctl 593
Cdd:PRK15370  190 LTTIPACIP--EQITTLILDNNELKSLPENLQG--NIKTLYANSNQLTSIP-------------------ATLP------ 240

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953292609 594 ENLQVLDLSINQIQNVPSDICNlkRIQKLNISSNqfmyfpielcrlqsleelnisqingrKLTRLPEELSNltQLKRLDI 673
Cdd:PRK15370  241 DTIQEMELSINRITELPERLPS--ALQSLDLFHN--------------------------KISCLPENLPE--ELRYLSV 290

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953292609 674 SDNAIREIPRNIGElrSLVSLNAYNNQISYLPPS--------------FLCL-----NDLQQLNLSGNNLTALPIGIHNl 734
Cdd:PRK15370  291 YDNSIRTLPAHLPS--GITHLNVQSNSLTALPETlppglktleagenaLTSLpaslpPELQVLDVSKNQITVLPETLPP- 367

                         250
                  ....*....|....*..
gi 1953292609 735 fSLKEINFDDNPLLRPP 751
Cdd:PRK15370  368 -TITTLDVSRNALTNLP 383
PRK15387 PRK15387
type III secretion system effector E3 ubiquitin transferase SspH2;
504-740 9.46e-10

type III secretion system effector E3 ubiquitin transferase SspH2;


Pssm-ID: 185285 [Multi-domain]  Cd Length: 788  Bit Score: 62.49  E-value: 9.46e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953292609 504 LYYLNFNGNYISEIPVdisFSKQLLNLELNKN-------------KLLIFSEHLCSLT----NLEYLDLGKNQIRKIPPS 566
Cdd:PRK15387  244 LRTLEVSGNQLTSLPV---LPPGLLELSIFSNplthlpalpsglcKLWIFGNQLTSLPvlppGLQELSVSDNQLASLPAL 320

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953292609 567 ISNMVSLQVLilcCNKFEVFPIEVCTLENLQVLDLSINQIQNVPSDIcnlkriQKLNISSNQFMYFPielCRLQSLEELN 646
Cdd:PRK15387  321 PSELCKLWAY---NNQLTSLPTLPSGLQELSVSDNQLASLPTLPSEL------YKLWAYNNRLTSLP---ALPSGLKELI 388

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953292609 647 ISqinGRKLTRLPEELSnltQLKRLDISDNAIREIPRnigeLRS-LVSLNAYNNQISYLPPSFLCLNDLQQLNLSGNnlt 725
Cdd:PRK15387  389 VS---GNRLTSLPVLPS---ELKELMVSGNRLTSLPM----LPSgLLSLSVYRNQLTRLPESLIHLSSETTVNLEGN--- 455

                         250
                  ....*....|....*
gi 1953292609 726 alPIGIHNLFSLKEI 740
Cdd:PRK15387  456 --PLSERTLQALREI 468
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 141-334 2.99e-09

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 61.02  E-value: 2.99e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953292609 141 SSQLSEENQKGLGLESDNFTVNLKAKGLQ-EFPKDILKSKSVKYLYLDGNQIKNFKGADSGDLLGLEILSLQENGLLSLP 219
Cdd:PLN00113  389 SNSLEGEIPKSLGACRSLRRVRLQDNSFSgELPSEFTKLPLVYFLDISNNNLQGRINSRKWDMPSLQMLSLARNKFFGGL 468

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953292609 220 PEIQLFHNLRILNVSHNQISH-IPKEISQLGNIRQLFLNNNCIEN-FPSGLKSLGNLEILSLAKNKLR-HIPDTLSGLKN 296
Cdd:PLN00113  469 PDSFGSKRLENLDLSRNQFSGaVPRKLGSLSELMQLKLSENKLSGeIPDELSSCKKLVSLDLSHNQLSgQIPASFSEMPV 548

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|
gi 1953292609 297 LKVLNLEYNQLT-IFPKVLCFLPKLISLILTGNLI-SSLP 334
Cdd:PLN00113  549 LSQLDLSQNQLSgEIPKNLGNVESLVQVNISHNHLhGSLP 588
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 511-683 1.35e-08

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 55.95  E-value: 1.35e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953292609 511 GNYISEIPvDISFSKQLLNLELNKNKLLIFsEHLCSLTNLEYLDLGKNQIRKIpPSISNMVSLQVLILCC------NKFE 584
Cdd:cd21340    33 DNKITKIE-NLEFLTNLTHLYLQNNQIEKI-ENLENLVNLKKLYLGGNRISVV-EGLENLTNLEELHIENqrlppgEKLT 109

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953292609 585 VFPIEVCTL-ENLQVLDLSINQIQNVpSDICNLKRIQKLNISSNQfmyfpielcrLQSLEELNisqingrkltrlpEELS 663
Cdd:cd21340   110 FDPRSLAALsNSLRVLNISGNNIDSL-EPLAPLRNLEQLDASNNQ----------ISDLEELL-------------DLLS 165

                         170       180
                  ....*....|....*....|
gi 1953292609 664 NLTQLKRLDISDNAIREIPR 683
Cdd:cd21340   166 SWPSLRELDLTGNPVCKKPK 185
PRK15387 PRK15387
type III secretion system effector E3 ubiquitin transferase SspH2;
204-470 6.88e-08

type III secretion system effector E3 ubiquitin transferase SspH2;


Pssm-ID: 185285 [Multi-domain]  Cd Length: 788  Bit Score: 56.32  E-value: 6.88e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953292609 204 GLEILSLQENGLLSLPPeiQLFHNLRILNVSHNQISHIPKEISQLgniRQLFLNNNCIENFPSGLKSLGNLEILSlakNK 283
Cdd:PRK15387  202 GNAVLNVGESGLTTLPD--CLPAHITTLVIPDNNLTSLPALPPEL---RTLEVSGNQLTSLPVLPPGLLELSIFS---NP 273

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953292609 284 LRHIPDTLSGLKNLKVLNleyNQLTIFPkvlCFLPKLISLILTGNLISSLPKeirELKNLEKLLLDHNKLTFL------- 356
Cdd:PRK15387  274 LTHLPALPSGLCKLWIFG---NQLTSLP---VLPPGLQELSVSDNQLASLPA---LPSELCKLWAYNNQLTSLptlpsgl 344

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953292609 357 ---AVEIFQLLKMKELQLTGNKLEVISHKIENFKEL----RILILDKNLLKEVPEKISHcvmLEYLSLSCNKLMELPkni 429
Cdd:PRK15387  345 qelSVSDNQLASLPTLPSELYKLWAYNNRLTSLPALpsglKELIVSGNRLTSLPVLPSE---LKELMVSGNRLTSLP--- 418

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|.
gi 1953292609 430 YKLKNLRKLRVNTNNIVRIPEDISHLNNIISLEFSGNIITD 470
Cdd:PRK15387  419 MLPSGLLSLSVYRNQLTRLPESLIHLSSETTVNLEGNPLSE 459
LRR_8 pfam13855
Leucine rich repeat;
273-330 7.62e-08

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 49.83  E-value: 7.62e-08
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953292609 273 NLEILSLAKNKLRHI-PDTLSGLKNLKVLNLEYNQLT-IFPKVLCFLPKLISLILTGNLI 330
Cdd:pfam13855   2 NLRSLDLSNNRLTSLdDGAFKGLSNLKVLDLSNNLLTtLSPGAFSGLPSLRYLDLSGNRL 61
PLN03210 PLN03210
Resistant to P. syringae 6; Provisional
 368-719 9.13e-08

Resistant to P. syringae 6; Provisional


Pssm-ID: 215633 [Multi-domain]  Cd Length: 1153  Bit Score: 56.04  E-value: 9.13e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953292609  368 ELQLTGNKLEVISHKIENFKELRILIL--DKNLlKEVPEkISHCVMLEYLSLS-CNKLMELPKNIYKLKNLRKLRVN-TN 443
Cdd:PLN03210   615 KLQMQGSKLEKLWDGVHSLTGLRNIDLrgSKNL-KEIPD-LSMATNLETLKLSdCSSLVELPSSIQYLNKLEDLDMSrCE 692

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953292609  444 NIVRIPEDIShLNNIISLEFSG----NIITDIPievkncKKITKVELSYNKIMYFPVGLcALDSLYYLNfngnyISEIPv 519
Cdd:PLN03210   693 NLEILPTGIN-LKSLYRLNLSGcsrlKSFPDIS------TNISWLDLDETAIEEFPSNL-RLENLDELI-----LCEMK- 758

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953292609  520 disfSKQLLNLELNKNKLLIFSEHlcSLTNLEYLDLgkNQIRKIPPSISNMVSLQVL-ILCCNKFEVFPIEVcTLENLQV 598
Cdd:PLN03210   759 ----SEKLWERVQPLTPLMTMLSP--SLTRLFLSDI--PSLVELPSSIQNLHKLEHLeIENCINLETLPTGI-NLESLES 829

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953292609  599 LDLS-INQIQNVPSDICNlkrIQKLNISSNQFMYFPIELCRLQSLEELNISQINgrKLTRLPEELSNLTQLKRLDISDNA 677
Cdd:PLN03210   830 LDLSgCSRLRTFPDISTN---ISDLNLSRTGIEEVPWWIEKFSNLSFLDMNGCN--NLQRVSLNISKLKHLETVDFSDCG 904

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|..
gi 1953292609  678 irEIPRNIGELRSLVSLNAYNNQISYLPPSFlCLNDLQQLNL 719
Cdd:PLN03210   905 --ALTEASWNGSPSEVAMATDNIHSKLPSTV-CINFINCFNL 943
PLN03150 PLN03150
hypothetical protein; Provisional
 658-748 1.74e-06

hypothetical protein; Provisional


Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 51.74  E-value: 1.74e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953292609 658 LPEELSNLTQLKRLDISDNAIR-EIPRNIGELRSLVSLN-AYNNQISYLPPSFLCLNDLQQLNLSGNNLTA-LPIGIHN- 733
Cdd:PLN03150  434 IPNDISKLRHLQSINLSGNSIRgNIPPSLGSITSLEVLDlSYNSFNGSIPESLGQLTSLRILNLNGNSLSGrVPAALGGr 513

                          90
                  ....*....|....*
gi 1953292609 734 LFSLKEINFDDNPLL 748
Cdd:PLN03150  514 LLHRASFNFTDNAGL 528
LRR_8 pfam13855
Leucine rich repeat;
227-307 2.65e-06

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 45.21  E-value: 2.65e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953292609 227 NLRILNVSHNQISHIPkeisqlgnirqlflnnncienfPSGLKSLGNLEILSLAKNKLRHI-PDTLSGLKNLKVLNLEYN 305
Cdd:pfam13855   2 NLRSLDLSNNRLTSLD----------------------DGAFKGLSNLKVLDLSNNLLTTLsPGAFSGLPSLRYLDLSGN 59


                  ..
gi 1953292609 306 QL 307
Cdd:pfam13855  60 RL 61
PRK15387 PRK15387
type III secretion system effector E3 ubiquitin transferase SspH2;
553-741 2.70e-06

type III secretion system effector E3 ubiquitin transferase SspH2;


Pssm-ID: 185285 [Multi-domain]  Cd Length: 788  Bit Score: 51.32  E-value: 2.70e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953292609 553 LDLGKNQIRKIPPSISNMVSlqVLILCCNKFEVFPievCTLENLQVLDLSINQIQNVPSDICNLkriQKLNISSNQFMYF 632
Cdd:PRK15387  206 LNVGESGLTTLPDCLPAHIT--TLVIPDNNLTSLP---ALPPELRTLEVSGNQLTSLPVLPPGL---LELSIFSNPLTHL 277

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953292609 633 PI---ELCRLQsleelnisqINGRKLTRLPEELSNLTQLKrldISDNAIREIPRNIGELrslVSLNAYNNQISYLP--PS 707
Cdd:PRK15387  278 PAlpsGLCKLW---------IFGNQLTSLPVLPPGLQELS---VSDNQLASLPALPSEL---CKLWAYNNQLTSLPtlPS 342

                         170       180       190
                  ....*....|....*....|....*....|....
gi 1953292609 708 flclnDLQQLNLSGNNLTALPIGIHNLFSLKEIN 741
Cdd:PRK15387  343 -----GLQELSVSDNQLASLPTLPSELYKLWAYN 371
PLN03210 PLN03210
Resistant to P. syringae 6; Provisional
 527-738 5.52e-06

Resistant to P. syringae 6; Provisional


Pssm-ID: 215633 [Multi-domain]  Cd Length: 1153  Bit Score: 50.26  E-value: 5.52e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953292609  527 LLNLELNKNKLLIFSEHLCSLTNLEYLDLGKNQIRKIPPSISNMVSLQVLILC-CNKFEVFPIEVCTLENLQVLDLS-IN 604
Cdd:PLN03210   613 LVKLQMQGSKLEKLWDGVHSLTGLRNIDLRGSKNLKEIPDLSMATNLETLKLSdCSSLVELPSSIQYLNKLEDLDMSrCE 692

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953292609  605 QIQNVPSDIcNLKRIQKLN------------ISSN---------QFMYFPIELcRLQSLEELNISQINGRKLTRLPEELS 663
Cdd:PLN03210   693 NLEILPTGI-NLKSLYRLNlsgcsrlksfpdISTNiswldldetAIEEFPSNL-RLENLDELILCEMKSEKLWERVQPLT 770

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953292609  664 NLTQ-----LKRLDISDN-AIREIPRNIGELRSLVSLNAYNNQISYLPPSFLCLNDLQQLNLSG-NNLTALPIGIHNLFS 736
Cdd:PLN03210   771 PLMTmlspsLTRLFLSDIpSLVELPSSIQNLHKLEHLEIENCINLETLPTGINLESLESLDLSGcSRLRTFPDISTNISD 850


                   ..
gi 1953292609  737 LK 738
Cdd:PLN03210   851 LN 852
PLN03150 PLN03150
hypothetical protein; Provisional
 241-308 9.43e-06

hypothetical protein; Provisional


Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 49.43  E-value: 9.43e-06
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953292609 241 IPKEISQLGNIRQLFLNNNCIE-NFPSGLKSLGNLEILSLAKNKLR-HIPDTLSGLKNLKVLNLEYNQLT 308
Cdd:PLN03150  434 IPNDISKLRHLQSINLSGNSIRgNIPPSLGSITSLEVLDLSYNSFNgSIPESLGQLTSLRILNLNGNSLS 503
PLN03150 PLN03150
hypothetical protein; Provisional
 448-518 2.30e-05

hypothetical protein; Provisional


Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 47.89  E-value: 2.30e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1953292609 448 IPEDISHLNNIISLEFSGNIIT-DIPIEVKNCKKITKVELSYNKIM-YFPVGLCALDSLYYLNFNGNYIS-EIP 518
Cdd:PLN03150  434 IPNDISKLRHLQSINLSGNSIRgNIPPSLGSITSLEVLDLSYNSFNgSIPESLGQLTSLRILNLNGNSLSgRVP 507
LRR_8 pfam13855
Leucine rich repeat;
666-724 8.31e-05

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 40.97  E-value: 8.31e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1953292609 666 TQLKRLDISDNAIREI-PRNIGELRSLVSLNAYNNQISYLPP-SFLCLNDLQQLNLSGNNL 724
Cdd:pfam13855   1 PNLRSLDLSNNRLTSLdDGAFKGLSNLKVLDLSNNLLTTLSPgAFSGLPSLRYLDLSGNRL 61
PLN03150 PLN03150
hypothetical protein; Provisional
 609-686 1.03e-04

hypothetical protein; Provisional


Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 45.96  E-value: 1.03e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953292609 609 VPSDICNLKRIQKLNISSNQFM-YFPIELCRLQSLEELNIS--QINGrkltRLPEELSNLTQLKRLDISDNAIR-EIPRN 684
Cdd:PLN03150  434 IPNDISKLRHLQSINLSGNSIRgNIPPSLGSITSLEVLDLSynSFNG----SIPESLGQLTSLRILNLNGNSLSgRVPAA 509


                  ..
gi 1953292609 685 IG 686
Cdd:PLN03150  510 LG 511
LRR_8 pfam13855
Leucine rich repeat;
204-259 1.21e-04

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 40.59  E-value: 1.21e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1953292609 204 GLEILSLQENGLLSLPPEI-QLFHNLRILNVSHNQISHI-PKEISQLGNIRQLFLNNN 259
Cdd:pfam13855   2 NLRSLDLSNNRLTSLDDGAfKGLSNLKVLDLSNNLLTTLsPGAFSGLPSLRYLDLSGN 59
RNA1 COG5238
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ...
 162-336 3.74e-04

Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];


Pssm-ID: 444072 [Multi-domain]  Cd Length: 434  Bit Score: 44.01  E-value: 3.74e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953292609 162 NLKAKGLQEFPKDILKSKSVKYLYLDGNQI---------KNFKGADSGDLLGLEILSLQENGLLSLPPEIQLFHNLRILN 232
Cdd:COG5238   191 QIGDEGIEELAEALTQNTTVTTLWLKRNPIgdegaeilaEALKGNKSLTTLDLSNNQIGDEGVIALAEALKNNTTVETLY 270

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953292609 233 VSHNQISH-----IPKEISQLGNIRQLFLNNNCI-----ENFPSGLKSLGNLEILSLAKNKLRH-----IPDTLSGLKNL 297
Cdd:COG5238   271 LSGNQIGAegaiaLAKALQGNTTLTSLDLSVNRIgdegaIALAEGLQGNKTLHTLNLAYNGIGAqgaiaLAKALQENTTL 350

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....
gi 1953292609 298 KVLNLEYNQLT-----IFPKVLCFLPKLISLILTGNLISSLPKE 336
Cdd:COG5238   351 HSLDLSDNQIGdegaiALAKYLEGNTTLRELNLGKNNIGKQGAE 394
PLN03150 PLN03150
hypothetical protein; Provisional
 161-239 1.55e-03

hypothetical protein; Provisional


Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 42.11  E-value: 1.55e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953292609 161 VNLKAKGLQEF-PKDILKSKSVKYLYLDGNQIKNFKGADSGDLLGLEILSLQENGLL-SLPPEIQLFHNLRILNVSHNQI 238
Cdd:PLN03150  423 LGLDNQGLRGFiPNDISKLRHLQSINLSGNSIRGNIPPSLGSITSLEVLDLSYNSFNgSIPESLGQLTSLRILNLNGNSL 502


                  .
gi 1953292609 239 S 239
Cdd:PLN03150  503 S 503
LRR_8 pfam13855
Leucine rich repeat;
572-629 2.03e-03

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 37.12  E-value: 2.03e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953292609 572 SLQVLILCCNKFEVFPIEVCT-LENLQVLDLSINQIQNV-PSDICNLKRIQKLNISSNQF 629
Cdd:pfam13855   2 NLRSLDLSNNRLTSLDDGAFKgLSNLKVLDLSNNLLTTLsPGAFSGLPSLRYLDLSGNRL 61
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 277-472 2.42e-03

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 40.15  E-value: 2.42e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953292609 277 LSLAKNKLRHIPDtLSGLKNLKVLNLEYNQLTIFPKvLCFLPKLISLILTGNLISSLPkEIRELKNLEKLLLDHNKLTFl 356
Cdd:cd21340     7 LYLNDKNITKIDN-LSLCKNLKVLYLYDNKITKIEN-LEFLTNLTHLYLQNNQIEKIE-NLENLVNLKKLYLGGNRISV- 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953292609 357 aVEIFQLLK-MKELQLTGNKLEvishkiENFKelriLILDKNLLKEvpekISHCvmLEYLSLSCNKLMELpKNIYKLKNL 435
Cdd:cd21340    83 -VEGLENLTnLEELHIENQRLP------PGEK----LTFDPRSLAA----LSNS--LRVLNISGNNIDSL-EPLAPLRNL 144

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|
gi 1953292609 436 RKLRVNTNNIVRIPE---DISHLNNIISLEFSGNIITDIP 472
Cdd:cd21340   145 EQLDASNNQISDLEElldLLSSWPSLRELDLTGNPVCKKP 184
LRR_RI cd00116
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ...
 641-729 4.59e-03

Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).


Pssm-ID: 238064 [Multi-domain]  Cd Length: 319  Bit Score: 40.03  E-value: 4.59e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953292609 641 SLEELNISQ--INGRKLTRLPEELSNLTQLKRLDISDNAIRE--IPRNIGELRS---LVSLNAYNNQISYLPPSFLC--- 710
Cdd:cd00116   138 ALEKLVLGRnrLEGASCEALAKALRANRDLKELNLANNGIGDagIRALAEGLKAncnLEVLDLNNNGLTDEGASALAetl 217

                          90       100
                  ....*....|....*....|.
gi 1953292609 711 --LNDLQQLNLSGNNLTALPI 729
Cdd:cd00116   218 asLKSLEVLNLGDNNLTDAGA 238
LRR_8 pfam13855
Leucine rich repeat;
548-606 5.72e-03

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 35.96  E-value: 5.72e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1953292609 548 TNLEYLDLGKNQIRKIPPSI-SNMVSLQVLILCCNKFEVFPIEVCT-LENLQVLDLSINQI 606
Cdd:pfam13855   1 PNLRSLDLSNNRLTSLDDGAfKGLSNLKVLDLSNNLLTTLSPGAFSgLPSLRYLDLSGNRL 61
DEATH smart00005
DEATH domain, found in proteins involved in cell death (apoptosis); Alpha-helical domain ...
 778-864 7.56e-03

DEATH domain, found in proteins involved in cell death (apoptosis); Alpha-helical domain present in a variety of proteins with apoptotic functions. Some (but not all) of these domains form homotypic and heterotypic dimers.


Pssm-ID: 214467 [Multi-domain]  Cd Length: 88  Bit Score: 36.62  E-value: 7.56e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953292609  778 LEKIFIIVANNITITNFKYLCQKLNLaiSETDM---STKSPVSLSERVLQALHKWKT-ESINLSLttaalrDQLTRALTM 853
Cdd:smart00005   4 TRQKLAKLLDHPLGLDWRELARKLGL--SEADIdqiRTEAPRDLAEQSVQLLRLWEQrEGKNATL------GTLLEALRK 75

                           90
                   ....*....|.
gi 1953292609  854 IGAYEIMDKIT 864
Cdd:smart00005  76 MGRDDAVELLR 86
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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