|
Name |
Accession |
Description |
Interval |
E-value |
| Prolidase |
cd01087 |
Prolidase. E.C. 3.4.13.9. Also known as Xaa-Pro dipeptidase, X-Pro dipeptidase, proline ... |
173-410 |
2.78e-118 |
|
Prolidase. E.C. 3.4.13.9. Also known as Xaa-Pro dipeptidase, X-Pro dipeptidase, proline dipeptidase., imidodipeptidase, peptidase D, gamma-peptidase. Catalyses hydrolysis of Xaa-Pro dipeptides; also acts on aminoacyl-hydroxyproline analogs. No action on Pro-Pro.
Pssm-ID: 238520 [Multi-domain] Cd Length: 243 Bit Score: 344.56 E-value: 2.78e-118
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958791399 173 IKRMQIAGKLTSEAFIETMFASKAPVDEAFLYAKFEFECRARGADiLAYPPVVAGGNRSNTLHYVKNNQLIKDGEMVLLD 252
Cdd:cd01087 1 IELMRKACDISAEAHRAAMKASRPGMSEYELEAEFEYEFRSRGAR-LAYSYIVAAGSNAAILHYVHNDQPLKDGDLVLID 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958791399 253 GGCESSCYVSDITRTWPVNGRFTAPQAELYEAVLEIQKACLTLCSPGTSLENIYSMMLTLMGQKLKDLGIIKTSKESAFK 332
Cdd:cd01087 80 AGAEYGGYASDITRTFPVNGKFTDEQRELYEAVLAAQKAAIAACKPGVSYEDIHLLAHRVLAEGLKELGILKGDVDEIVE 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958791399 333 --AARKYCPHHVGHYLGMDVHDTPDMPRSL----PLQPGMVITVEPGIYIPEGDTDAPEKFRGLGVRIEDDVVVTQDSPL 406
Cdd:cd01087 160 sgAYAKFFPHGLGHYLGLDVHDVGGYLRYLrrarPLEPGMVITIEPGIYFIPDLLDVPEYFRGGGIRIEDDVLVTEDGPE 239
|
....
gi 1958791399 407 ILSA 410
Cdd:cd01087 240 NLTR 243
|
|
| PRK10879 |
PRK10879 |
proline aminopeptidase P II; Provisional |
2-420 |
3.57e-87 |
|
proline aminopeptidase P II; Provisional
Pssm-ID: 182804 [Multi-domain] Cd Length: 438 Bit Score: 271.98 E-value: 3.57e-87
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958791399 2 ALVHKEAQGHSGtdhtvVVLSNPIHYMSNDIPYTFHQDNSFLYLCGFQEPDSILVLQSCSGKQlpsHKAMLFVPRRDPGR 81
Cdd:PRK10879 12 ALLAKMQPGSAA-----LIFAAPEATRSADSEYPYRQNSDFWYFTGFNEPEAVLVLIKSDDTH---NHSVLFNRVRDLTA 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958791399 82 ELWDGPRSGTDGAIALTGVDDAYPLEEFQHLLPKLRAETNMVWydwmkpsHAQLHSDYMQPLTEAkATSKNKVRSVQHL- 160
Cdd:PRK10879 84 EIWFGRRLGQDAAPEKLGVDRALPFSEINQQLYQLLNGLDVVY-------HAQGEYAYADEIVFS-ALEKLRKGSRQNLt 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958791399 161 -----------IQHLRLIKSPAEIKRMQIAGKLTSEAFIETMFASKAPVDEAFLYAKFEFECRARGADILAYPPVVAGGN 229
Cdd:PRK10879 156 apatltdwrpwVHEMRLFKSPEEIAVLRRAGEISALAHTRAMEKCRPGMFEYQLEGEIHHEFNRHGARYPSYNTIVGSGE 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958791399 230 RSNTLHYVKNNQLIKDGEMVLLDGGCESSCYVSDITRTWPVNGRFTAPQAELYEAVLEIQKACLTLCSPGTSLENIYSMM 309
Cdd:PRK10879 236 NGCILHYTENESEMRDGDLVLIDAGCEYKGYAGDITRTFPVNGKFTPAQREIYDIVLESLETSLRLYRPGTSIREVTGEV 315
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958791399 310 LTLMGQKLKDLGIIKTSKES--AFKAARKYCPHHVGHYLGMDVHDTPD--MPRSLPLQPGMVITVEPGIYIPEgDTDAPE 385
Cdd:PRK10879 316 VRIMVSGLVKLGILKGDVDQliAENAHRPFFMHGLSHWLGLDVHDVGVygQDRSRILEPGMVLTVEPGLYIAP-DADVPE 394
|
410 420 430
....*....|....*....|....*....|....*
gi 1958791399 386 KFRGLGVRIEDDVVVTQDSPLILSADCPKEVNDIE 420
Cdd:PRK10879 395 QYRGIGIRIEDDIVITETGNENLTASVVKKPDEIE 429
|
|
| PepP |
COG0006 |
Xaa-Pro aminopeptidase [Amino acid transport and metabolism]; |
152-419 |
3.55e-76 |
|
Xaa-Pro aminopeptidase [Amino acid transport and metabolism];
Pssm-ID: 439777 [Multi-domain] Cd Length: 299 Bit Score: 238.95 E-value: 3.55e-76
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958791399 152 NKVRSVQHLIQHLRLIKSPAEIKRMQIAGKLTSEAFIETMFASKAPVDEAFLYAKFEFECRARGADILAYPPVVAGGNRS 231
Cdd:COG0006 58 RELVDASDLLEELRAIKSPEEIELMRKAARIADAAHEAALAALRPGVTEREVAAELEAAMRRRGAEGPSFDTIVASGENA 137
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958791399 232 NTLHYVKNNQLIKDGEMVLLDGGCESSCYVSDITRTWPVnGRFTAPQAELYEAVLEIQKACLTLCSPGTSLENIYsmmlT 311
Cdd:COG0006 138 AIPHYTPTDRPLKPGDLVLIDAGAEYDGYTSDITRTVAV-GEPSDEQREIYEAVLEAQEAAIAALKPGVTGGEVD----A 212
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958791399 312 LMGQKLKDLGIiktskesafkaaRKYCPHHVGHYLGMDVHDTPDM--PRSLPLQPGMVITVEPGIYIPEgdtdapekfrG 389
Cdd:COG0006 213 AARDVLAEAGY------------GEYFPHGTGHGVGLDVHEGPQIspGNDRPLEPGMVFTIEPGIYIPG----------I 270
|
250 260 270
....*....|....*....|....*....|
gi 1958791399 390 LGVRIEDDVVVTQDSPLILSaDCPKEVNDI 419
Cdd:COG0006 271 GGVRIEDTVLVTEDGAEVLT-RLPRELLEL 299
|
|
| Peptidase_M24 |
pfam00557 |
Metallopeptidase family M24; This family contains metallopeptidases. It also contains ... |
174-401 |
1.31e-62 |
|
Metallopeptidase family M24; This family contains metallopeptidases. It also contains non-peptidase homologs such as the N terminal domain of Spt16 which is a histone H3-H4 binding module.
Pssm-ID: 459852 [Multi-domain] Cd Length: 208 Bit Score: 200.93 E-value: 1.31e-62
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958791399 174 KRMQIAGKLTSEAFIETMFASKAPVDEAFLYAKFE-FECRARGADILAYPPVVAGGNRSNTLHYVKNNQLIKDGEMVLLD 252
Cdd:pfam00557 1 ELMRKAARIAAAALEAALAAIRPGVTERELAAELEaARLRRGGARGPAFPPIVASGPNAAIPHYIPNDRVLKPGDLVLID 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958791399 253 GGCE-SSCYVSDITRTWpVNGRFTAPQAELYEAVLEIQKACLTLCSPGTSLENIYSMMLTLMgqklKDLGIIktskesaf 331
Cdd:pfam00557 81 VGAEyDGGYCSDITRTF-VVGKPSPEQRELYEAVLEAQEAAIAAVKPGVTGGDVDAAAREVL----EEAGLG-------- 147
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1958791399 332 kaarKYCPHHVGHYLGMDVHDTPDMPRS---LPLQPGMVITVEPGIYIPEGDTdapekfrglGVRIEDDVVVT 401
Cdd:pfam00557 148 ----EYFPHGLGHGIGLEVHEGPYISRGgddRVLEPGMVFTIEPGIYFIPGWG---------GVRIEDTVLVT 207
|
|
| APP-like |
cd01092 |
Similar to Prolidase and Aminopeptidase P. The members of this subfamily presumably catalyse ... |
173-405 |
6.85e-48 |
|
Similar to Prolidase and Aminopeptidase P. The members of this subfamily presumably catalyse hydrolysis of Xaa-Pro dipeptides and/or release of any N-terminal amino acid, including proline, that is linked with proline.
Pssm-ID: 238525 [Multi-domain] Cd Length: 208 Bit Score: 162.68 E-value: 6.85e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958791399 173 IKRMQIAGKLTSEAFIETMFASKAPVDEAFLYAKFEFECRARGADILAYPPVVAGGNRSNTLHYVKNNQLIKDGEMVLLD 252
Cdd:cd01092 1 IELLRKAARIADKAFEELLEFIKPGMTEREVAAELEYFMRKLGAEGPSFDTIVASGPNSALPHGVPSDRKIEEGDLVLID 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958791399 253 GGCESSCYVSDITRTWPVnGRFTAPQAELYEAVLEIQKACLTLCSPGTSLENIysmmltlmgqklkDlgiiktskesafK 332
Cdd:cd01092 81 FGAIYDGYCSDITRTVAV-GEPSDELKEIYEIVLEAQQAAIKAVKPGVTAKEV-------------D------------K 134
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958791399 333 AAR---------KYCPHHVGHYLGMDVHDTPD-MPRS-LPLQPGMVITVEPGIYIPEgdtdapekfRGlGVRIEDDVVVT 401
Cdd:cd01092 135 AARdvieeagygEYFIHRTGHGVGLEVHEAPYiSPGSdDVLEEGMVFTIEPGIYIPG---------KG-GVRIEDDVLVT 204
|
....
gi 1958791399 402 QDSP 405
Cdd:cd01092 205 EDGC 208
|
|
| AMP_N |
smart01011 |
Aminopeptidase P, N-terminal domain; This domain is structurally very similar to the ... |
15-127 |
5.93e-43 |
|
Aminopeptidase P, N-terminal domain; This domain is structurally very similar to the creatinase N-terminal domain. However, little or no sequence similarity exists between the two families.
Pssm-ID: 198079 Cd Length: 135 Bit Score: 147.39 E-value: 5.93e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958791399 15 DHTVVVLSNPIHYMSNDIPYTFHQDNSFLYLCGFQEPDSILVLQscsgKQLPSHKAMLFVPRRDPGRELWDGPRSGTDGA 94
Cdd:smart01011 20 GSVAVLPAGPEKVRSNDTDYPFRQDSDFYYLTGFDEPDAVLVLD----PSGGGGKSTLFVPPRDPEDELWDGPRLGLEEA 95
|
90 100 110
....*....|....*....|....*....|...
gi 1958791399 95 IALTGVDDAYPLEEFQHLLPKLRAETNMVWYDW 127
Cdd:smart01011 96 KEKFGVDEVYPIDELDAVLPGLLAGAGTVYYLL 128
|
|
| AMP_N |
pfam05195 |
Aminopeptidase P, N-terminal domain; This domain is structurally very similar to the ... |
13-124 |
1.02e-41 |
|
Aminopeptidase P, N-terminal domain; This domain is structurally very similar to the creatinase N-terminal domain (pfam01321). However, little or no sequence similarity exists between the two families.
Pssm-ID: 461581 [Multi-domain] Cd Length: 121 Bit Score: 143.42 E-value: 1.02e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958791399 13 GTDHTVVVLSNPIHYMSNDIPYTFHQDNSFLYLCGFQEPDSILVLQscsGKQLPSHKAMLFVPRRDPGRELWDGPRSGTD 92
Cdd:pfam05195 13 PPNSVAILPGAPEKYRNGDVFYPFRQDSDFYYLTGFNEPDAVLVLE---GGDIDSGKETLFVPPKDPEDEIWDGPRLGPE 89
|
90 100 110
....*....|....*....|....*....|..
gi 1958791399 93 GAIALTGVDDAYPLEEFQHLLPKLRAETNMVW 124
Cdd:pfam05195 90 EAKELFGVDEVYPIDELDEVLPKLLKGRDTVY 121
|
|
| APP_MetAP |
cd01066 |
A family including aminopeptidase P, aminopeptidase M, and prolidase. Also known as ... |
173-401 |
1.75e-36 |
|
A family including aminopeptidase P, aminopeptidase M, and prolidase. Also known as metallopeptidase family M24. This family of enzymes is able to cleave amido-, imido- and amidino-containing bonds. Members exibit relatively narrow substrate specificity compared to other metallo-aminopeptidases, suggesting they play roles in regulation of biological processes rather than general protein degradation.
Pssm-ID: 238514 [Multi-domain] Cd Length: 207 Bit Score: 132.58 E-value: 1.75e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958791399 173 IKRMQIAGKLTSEAFIETMFASKAPVDEAFLYAKFEFECRARGAdILAYPPVVAGGNRSNTLHYVKNNQLIKDGEMVLLD 252
Cdd:cd01066 1 IARLRKAAEIAEAAMAAAAEAIRPGVTEAEVAAAIEQALRAAGG-YPAGPTIVGSGARTALPHYRPDDRRLQEGDLVLVD 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958791399 253 GGCESSCYVSDITRTWPVnGRFTAPQAELYEAVLEIQKACLTLCSPGTSLENIYSMMLtlmgQKLKDLGiiktskesafk 332
Cdd:cd01066 80 LGGVYDGYHADLTRTFVI-GEPSDEQRELYEAVREAQEAALAALRPGVTAEEVDAAAR----EVLEEHG----------- 143
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1958791399 333 aARKYCPHHVGHYLGMDVHDTPDMPR--SLPLQPGMVITVEPGIYIPEGDtdapekfrglGVRIEDDVVVT 401
Cdd:cd01066 144 -LGPNFGHRTGHGIGLEIHEPPVLKAgdDTVLEPGMVFAVEPGLYLPGGG----------GVRIEDTVLVT 203
|
|
| PRK09795 |
PRK09795 |
aminopeptidase; Provisional |
164-416 |
2.98e-30 |
|
aminopeptidase; Provisional
Pssm-ID: 182080 [Multi-domain] Cd Length: 361 Bit Score: 120.04 E-value: 2.98e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958791399 164 LRLIKSPAEIKRMQIAGKL--TSEAFIETMFAskAPVDEAFLYAKFEFECRARGADILAYPPVVAGGNRSNTLHYVKNNQ 241
Cdd:PRK09795 124 LRQIKTPEEVEKIRLACGIadRGAEHIRRFIQ--AGMSEREIAAELEWFMRQQGAEKASFDTIVASGWRGALPHGKASDK 201
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958791399 242 LIKDGEMVLLDGGCESSCYVSDITRTWPVNGRfTAPQAE-----LYEAVLEIQKACLTLCSPGTSLENIysmmltlmgqk 316
Cdd:PRK09795 202 IVAAGEFVTLDFGALYQGYCSDMTRTLLVNGE-GVSAEShplfnVYQIVLQAQLAAISAIRPGVRCQQV----------- 269
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958791399 317 lkDLGIIKTSKESAFKaarKYCPHHVGHYLGMDVHDTPDM-PR-SLPLQPGMVITVEPGIYIPEgdtdapekfRGlGVRI 394
Cdd:PRK09795 270 --DDAARRVITEAGYG---DYFGHNTGHAIGIEVHEDPRFsPRdTTTLQPGMLLTVEPGIYLPG---------QG-GVRI 334
|
250 260
....*....|....*....|..
gi 1958791399 395 EDDVVVTQDSPLILSAdCPKEV 416
Cdd:PRK09795 335 EDVVLVTPQGAEVLYA-MPKTV 355
|
|
| PRK13607 |
PRK13607 |
proline dipeptidase; Provisional |
165-412 |
1.53e-23 |
|
proline dipeptidase; Provisional
Pssm-ID: 237444 [Multi-domain] Cd Length: 443 Bit Score: 101.89 E-value: 1.53e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958791399 165 RLIKSPAEIKRMQIAGKLTSEAFIetmfASKapvdEAFLYAKFEFECRAR-------GADILAYPPVVAGGNRSNTLHYV 237
Cdd:PRK13607 159 RAYKTDYELACMREAQKIAVAGHR----AAK----EAFRAGMSEFDINLAyltatgqRDNDVPYGNIVALNEHAAVLHYT 230
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958791399 238 KNNQLiKDGEM--VLLDGGCESSCYVSDITRTW--PVNGRFtapqAELYEAVLEIQKACLTLCSPGTSLENIYSMMLTLM 313
Cdd:PRK13607 231 KLDHQ-APAEMrsFLIDAGAEYNGYAADITRTYaaKEDNDF----AALIKDVNKEQLALIATMKPGVSYVDLHIQMHQRI 305
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958791399 314 GQKLKDLGIIKT-SKESAFKA--ARKYCPHHVGHYLGMDVHDT--------------PDMPRSL----PLQPGMVITVEP 372
Cdd:PRK13607 306 AKLLRKFQIVTGlSEEAMVEQgiTSPFFPHGLGHPLGLQVHDVagfmqddrgthlaaPEKHPYLrctrVLEPGMVLTIEP 385
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*.
gi 1958791399 373 GIYIPEG--------------DTDAPEKFR--GlGVRIEDDVVVTQDSPLILSADC 412
Cdd:PRK13607 386 GLYFIDSllaplregpfskhfNWQKIDALKpfG-GIRIEDNVVVHENGVENMTRDL 440
|
|
| APP |
cd01085 |
X-Prolyl Aminopeptidase 2. E.C. 3.4.11.9. Also known as X-Pro aminopeptidase, proline ... |
186-402 |
9.43e-15 |
|
X-Prolyl Aminopeptidase 2. E.C. 3.4.11.9. Also known as X-Pro aminopeptidase, proline aminopeptidase, aminopeptidase P, and aminoacylproline aminopeptidase. Catalyses release of any N-terminal amino acid, including proline, that is linked with proline, even from a dipeptide or tripeptide.
Pssm-ID: 238518 [Multi-domain] Cd Length: 224 Bit Score: 72.98 E-value: 9.43e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958791399 186 AFIETMFASKAPVDEAFLYAKFEfECRARGADI--LAYPPVVAGGNRSNTLHY---VKNNQLIKDGEMVLLDGGcesSCY 260
Cdd:cd01085 18 AWLEQEVPKGETITELSAADKLE-EFRRQQKGYvgLSFDTISGFGPNGAIVHYsptEESNRKISPDGLYLIDSG---GQY 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958791399 261 V---SDITRTWPVnGRFTAPQAELYEAVLEIQKACLTLCSP----GTSLENIYSMMLtlmgqklkdlgiiktskesaFKA 333
Cdd:cd01085 94 LdgtTDITRTVHL-GEPTAEQKRDYTLVLKGHIALARAKFPkgttGSQLDALARQPL--------------------WKA 152
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1958791399 334 ARKYcPH---H-VGHYLGmdVHDTP----DMPRSLPLQPGMVITVEPGIYIpegdtdaPEKFrglGVRIEDDVVVTQ 402
Cdd:cd01085 153 GLDY-GHgtgHgVGSFLN--VHEGPqsisPAPNNVPLKAGMILSNEPGYYK-------EGKY---GIRIENLVLVVE 216
|
|
| PRK05716 |
PRK05716 |
methionine aminopeptidase; Validated |
167-409 |
2.61e-09 |
|
methionine aminopeptidase; Validated
Pssm-ID: 235576 [Multi-domain] Cd Length: 252 Bit Score: 57.45 E-value: 2.61e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958791399 167 IKSPAEIKRMQIAGKLTSEAFIETMFASKAPV------DEAFLYAkfefecRARGAdI---LAYPP-----------VVA 226
Cdd:PRK05716 5 IKTPEEIEKMRVAGRLAAEVLDEIEPHVKPGVttkeldRIAEEYI------RDQGA-IpapLGYHGfpksictsvneVVC 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958791399 227 ggnrsntlHYVKNNQLIKDGEMVLLDGGCESSCYVSDITRTWPVngrftAPQAELYEAVLEIQKACLTLcspgtSLENIY 306
Cdd:PRK05716 78 --------HGIPSDKVLKEGDIVNIDVTVIKDGYHGDTSRTFGV-----GEISPEDKRLCEVTKEALYL-----GIAAVK 139
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958791399 307 SmmltlmGQKLKDLG--IIKTSKESAFKAARKYCphhvGHYLGMDVHDTPDMP------RSLPLQPGMVITVEPgiYIPE 378
Cdd:PRK05716 140 P------GARLGDIGhaIQKYAEAEGFSVVREYC----GHGIGRKFHEEPQIPhygapgDGPVLKEGMVFTIEP--MINA 207
|
250 260 270 280
....*....|....*....|....*....|....*....|
gi 1958791399 379 GDTDAPE---------KFRGLGVRIEDDVVVTQDSPLILS 409
Cdd:PRK05716 208 GKREVKTlkdgwtvvtKDGSLSAQYEHTVAVTEDGPEILT 247
|
|
| Map |
COG0024 |
Methionine aminopeptidase [Translation, ribosomal structure and biogenesis]; |
167-410 |
2.02e-08 |
|
Methionine aminopeptidase [Translation, ribosomal structure and biogenesis];
Pssm-ID: 439795 [Multi-domain] Cd Length: 250 Bit Score: 54.63 E-value: 2.02e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958791399 167 IKSPAEIKRMQIAGKLTSEAFIETMFASKAPVDEAFLYAKFEFECRARGAdilayppvvaggnRSNTLHY---------- 236
Cdd:COG0024 3 IKTPEEIEKMREAGRIVAEVLDELAEAVKPGVTTLELDRIAEEFIRDHGA-------------IPAFLGYygfpksicts 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958791399 237 --------VKNNQLIKDGEMVLLDGGCESSCYVSDITRTWPVnGRfTAPQAElyeAVLEIQKACLTL----CSPGTslen 304
Cdd:COG0024 70 vnevvvhgIPSDRVLKDGDIVNIDVGAILDGYHGDSARTFVV-GE-VSPEAR---RLVEVTEEALYAgiaaAKPGN---- 140
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958791399 305 iysmmltlmgqKLKDLG-IIKTSKESA-FKAARKYCphhvGHYLGMDVHDTPDMP------RSLPLQPGMVITVEPGIYi 376
Cdd:COG0024 141 -----------RLGDIGhAIQSYAESNgYSVVREFV----GHGIGREMHEEPQVPnygrpgRGPRLKPGMVLAIEPMIN- 204
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|..
gi 1958791399 377 pEGDTDapekfrglgVRIEDD------------------VVVTQDSPLILSA 410
Cdd:COG0024 205 -AGTPE---------VKVLDDgwtvvtkdgslsaqfehtVAVTEDGPEILTL 246
|
|
| CDC68-like |
cd01091 |
Related to aminopeptidase P and aminopeptidase M, a member of this domain family is present in ... |
221-408 |
1.11e-07 |
|
Related to aminopeptidase P and aminopeptidase M, a member of this domain family is present in cell division control protein 68, a transcription factor.
Pssm-ID: 238524 [Multi-domain] Cd Length: 243 Bit Score: 52.35 E-value: 1.11e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958791399 221 YPPVV-AGGNRSNTLHYVKNNQLIKDGEMVLLDGGCESSCYVSDITRTWPVNGrfTAPQAELYEAVLEIQKACLTLCSPG 299
Cdd:cd01091 65 YPPIIqSGGNYDLLKSSSSSDKLLYHFGVIICSLGARYKSYCSNIARTFLIDP--TSEQQKNYNFLLALQEEILKELKPG 142
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958791399 300 TSLENIYSMMLTLMGQKLKDLgiiktskesafkaaRKYCPHHVGHYLGMDVHDT-----PDMPRSlpLQPGMVITVEPGI 374
Cdd:cd01091 143 AKLSDVYQKTLDYIKKKKPEL--------------EPNFTKNLGFGIGLEFRESsliinAKNDRK--LKKGMVFNLSIGF 206
|
170 180 190
....*....|....*....|....*....|....
gi 1958791399 375 YIPEGDTDAPEKFRGLGVRIEDDVVVTQDSPLIL 408
Cdd:cd01091 207 SNLQNPEPKDKESKTYALLLSDTILVTEDEPAIV 240
|
|
| PRK15173 |
PRK15173 |
peptidase; Provisional |
160-375 |
3.71e-06 |
|
peptidase; Provisional
Pssm-ID: 185095 [Multi-domain] Cd Length: 323 Bit Score: 48.56 E-value: 3.71e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958791399 160 LIQHLRLIKSPAEIKRMQIAGKLTSEAFIETMFASKAPVDEAFLYAKFEFECRARGADILA-YPPVVAGGNRSNTLhyVK 238
Cdd:PRK15173 88 IFNELRVIKSPWEIKRLRKSAEITEYGITEASKLIRVGCTSAELTAAYKAAVMSKSETHFSrFHLISVGADFSPKL--IP 165
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958791399 239 NNQLIKDGEMVLLDGGCESSCYVSDITRTWPVnGRFTAPQAELYEAVLEIQKACLTLCSPGTSLENIYSMMLTlmgqklk 318
Cdd:PRK15173 166 SNTKACSGDLIKFDCGVDVDGYGADIARTFVV-GEPPEITRKIYQTIRTGHEHMLSMVAPGVKMKDVFDSTME------- 237
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 1958791399 319 dlgIIKTSKESAFKaaRKYCPHHVGHYLGMDVHDTPDMPRSLPLQPGMVITVEPGIY 375
Cdd:PRK15173 238 ---VIKKSGLPNYN--RGHLGHGNGVFLGLEESPFVSTHATESFTSGMVLSLETPYY 289
|
|
| PRK14575 |
PRK14575 |
putative peptidase; Provisional |
160-375 |
6.25e-06 |
|
putative peptidase; Provisional
Pssm-ID: 173039 [Multi-domain] Cd Length: 406 Bit Score: 48.16 E-value: 6.25e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958791399 160 LIQHLRLIKSPAEIKRMQIAGKLTSEAFIETMFASKAPVDEAFLYAKFEFECRARGADILA-YPPVVAGGNRSNTLhyVK 238
Cdd:PRK14575 171 IFNELRVIKSPWEIKRLRKSAEITEYGITEASKLIRVGCTSAELTAAYKAAVMSKSETHFSrFHLISVGADFSPKL--IP 248
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958791399 239 NNQLIKDGEMVLLDGGCESSCYVSDITRTWPVnGRFTAPQAELYEAVLEIQKACLTLCSPGTSLENIYSMMLTlmgqklk 318
Cdd:PRK14575 249 SNTKACSGDLIKFDCGVDVDGYGADIARTFVV-GEPPEITRKIYQTIRTGHEHMLSMVAPGVKMKDVFDSTME------- 320
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 1958791399 319 dlgIIKTSKESAFKaaRKYCPHHVGHYLGMDVHDTPDMPRSLPLQPGMVITVEPGIY 375
Cdd:PRK14575 321 ---VIKKSGLPNYN--RGHLGHGNGVFLGLEESPFVSTHATESFTSGMVLSLETPYY 372
|
|
| MetAP1 |
cd01086 |
Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and ... |
235-409 |
1.03e-05 |
|
Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and Peptidase M. Catalyzes release of N-terminal amino acids, preferentially methionine, from peptides and arylamides.
Pssm-ID: 238519 [Multi-domain] Cd Length: 238 Bit Score: 46.72 E-value: 1.03e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958791399 235 HYVKNNQLIKDGEMVLLDGGCESSCYVSDITRTWPVNGrfTAPQAElyeAVLEIQKACLTLcspgtSLENIysmmltLMG 314
Cdd:cd01086 68 HGIPDDRVLKDGDIVNIDVGVELDGYHGDSARTFIVGE--VSEEAK---KLVEVTEEALYK-----GIEAV------KPG 131
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958791399 315 QKLKDLG--IIKTSKESAFKAARKYCphhvGHYLGMDVHDTPDMP------RSLPLQPGMVITVEPgiYIPEGDTDapek 386
Cdd:cd01086 132 NRIGDIGhaIEKYAEKNGYSVVREFG----GHGIGRKFHEEPQIPnygrpgTGPKLKPGMVFTIEP--MINLGTYE---- 201
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 1958791399 387 frglgVRIEDD------------------VVVTQDSPLILS 409
Cdd:cd01086 202 -----VVTLPDgwtvvtkdgslsaqfehtVLITEDGPEILT 237
|
|
| PRK07281 |
PRK07281 |
methionyl aminopeptidase; |
342-410 |
4.28e-05 |
|
methionyl aminopeptidase;
Pssm-ID: 180918 Cd Length: 286 Bit Score: 45.22 E-value: 4.28e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958791399 342 VGHYLGMDVHDTPDMP------RSLPLQPGMVITVEPGIYIP--EGDTDAPEKFR------GLGVRIEDDVVVTQDSPLI 407
Cdd:PRK07281 197 VGHGVGPTMHEEPMVPnygtagRGLRLREGMVLTIEPMINTGtwEIDTDMKTGWAhktldgGLSCQYEHQFVITKDGPVI 276
|
...
gi 1958791399 408 LSA 410
Cdd:PRK07281 277 LTS 279
|
|
| PRK12896 |
PRK12896 |
methionine aminopeptidase; Reviewed |
167-408 |
8.82e-05 |
|
methionine aminopeptidase; Reviewed
Pssm-ID: 237252 [Multi-domain] Cd Length: 255 Bit Score: 43.67 E-value: 8.82e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958791399 167 IKSPAEIKRMQIAGKLTSEAfIETMFASKAP---VDEAFLYAKfEFECR--ARGADILAYP----------PVVAggnrs 231
Cdd:PRK12896 10 IKSPRELEKMRKIGRIVATA-LKEMGKAVEPgmtTKELDRIAE-KRLEEhgAIPSPEGYYGfpgstcisvnEEVA----- 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958791399 232 ntlHYVKNNQLIKDGEMVLLDGGCESSCYVSDITRTWPVngrftAPQAElyeavlEIQKacltLCSPGTSleniySMMLT 311
Cdd:PRK12896 83 ---HGIPGPRVIKDGDLVNIDVSAYLDGYHGDTGITFAV-----GPVSE------EAEK----LCRVAEE-----ALWAG 139
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958791399 312 LM----GQKLKDLG--IIKTSKESAFKAARKYCPHHVGHYL--GMDV--HDTPDMPRSLpLQPGMVITVEPgiYIPEGDT 381
Cdd:PRK12896 140 IKqvkaGRPLNDIGraIEDFAKKNGYSVVRDLTGHGVGRSLheEPSVilTYTDPLPNRL-LRPGMTLAVEP--FLNLGAK 216
|
250 260 270
....*....|....*....|....*....|....*.
gi 1958791399 382 DAPE---------KFRGLGVRIEDDVVVTQDSPLIL 408
Cdd:PRK12896 217 DAETlddgwtvvtPDKSLSAQFEHTVVVTRDGPEIL 252
|
|
| PRK14576 |
PRK14576 |
putative endopeptidase; Provisional |
160-409 |
1.41e-04 |
|
putative endopeptidase; Provisional
Pssm-ID: 173040 [Multi-domain] Cd Length: 405 Bit Score: 43.85 E-value: 1.41e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958791399 160 LIQHLRLIKSPAEIKRMQIAGKLTSEAFIETMFASKAPVDEAFLYAKFEfecrargADILAYPP--------VVAGGNRS 231
Cdd:PRK14576 170 LFNEIRMIKSPWEIEHLRKSAEITEYGIASAAKKIRVGCTAAELTAAFK-------AAVMSFPEtnfsrfnlISVGDNFS 242
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958791399 232 NTLhyVKNNQLIKDGEMVLLDGGCESSCYVSDITRTWpVNGRFTAPQAELYEAVLEIQKACLTLCSPGTSLENIYSmmlt 311
Cdd:PRK14576 243 PKI--IADTTPAKVGDLIKFDCGIDVAGYGADLARTF-VLGEPDKLTQQIYDTIRTGHEHMLSMVAPGVKLKAVFD---- 315
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958791399 312 lmgqklKDLGIIKTSKESAFKaaRKYCPHHVGHYLGMDVHDTPDMPRSLPLQPGMVITVEPGIYipegdtdapekfrGLG 391
Cdd:PRK14576 316 ------STMAVIKTSGLPHYN--RGHLGHGDGVFLGLEEVPFVSTQATETFCPGMVLSLETPYY-------------GIG 374
|
250 260
....*....|....*....|.
gi 1958791399 392 V---RIEDDVVVTQDSPLILS 409
Cdd:PRK14576 375 VgsiMLEDMILITDSGFEFLS 395
|
|
| PRK12318 |
PRK12318 |
methionyl aminopeptidase; |
162-374 |
1.63e-04 |
|
methionyl aminopeptidase;
Pssm-ID: 183434 [Multi-domain] Cd Length: 291 Bit Score: 43.27 E-value: 1.63e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958791399 162 QHLRLIKSPAEIKRMQIAGKLTSEAFIETMFASKAPV-----DEafLYAKFEFECRARGADI----LAYPPVVAGGNRSN 232
Cdd:PRK12318 38 QYDIIIKTPEQIEKIRKACQVTARILDALCEAAKEGVttnelDE--LSRELHKEYNAIPAPLnygsPPFPKTICTSLNEV 115
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958791399 233 TLHYVKNNQLIKDGEMVLLDGGCESSCYVSDITRTWPVnGRFTAPQAELYEAVLEIQKACLTLCSPGTSLENIysmmltl 312
Cdd:PRK12318 116 ICHGIPNDIPLKNGDIMNIDVSCIVDGYYGDCSRMVMI-GEVSEIKKKVCQASLECLNAAIAILKPGIPLYEI------- 187
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958791399 313 mGQKLKDLgiiktskesafkAARKYCP---HHVGHYLGMDVHDTPDMPR-----SLPLQPGMVITVEPGI 374
Cdd:PRK12318 188 -GEVIENC------------ADKYGFSvvdQFVGHGVGIKFHENPYVPHhrnssKIPLAPGMIFTIEPMI 244
|
|
| COG5406 |
COG5406 |
Nucleosome binding factor SPN, SPT16 subunit [Transcription, Replication, recombination and ... |
246-419 |
1.21e-03 |
|
Nucleosome binding factor SPN, SPT16 subunit [Transcription, Replication, recombination and repair, Chromatin structure and dynamics];
Pssm-ID: 227693 [Multi-domain] Cd Length: 1001 Bit Score: 41.15 E-value: 1.21e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958791399 246 GEMVLLDGGCESSCYVSDITRTWPVNGrfTAPQAELYEAVLEIQKACLTLCSPGTSLENIYSMMLTLMGQKLKDLG--II 323
Cdd:COG5406 270 GDVVLLSIGIRYNGYCSNMSRTILTDP--DSEQQKNYEFLYMLQKYILGLVRPGTDSGIIYSEAEKYISSNGPELGpnFI 347
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958791399 324 KTskesafkaarkycphhVGHYLGMDVHD-----TPDMPRSlpLQPGMVITvepgIYIPEGDTDAPEKFRGLGVRIEDDV 398
Cdd:COG5406 348 YN----------------VGLMIGIEFRSsqkpfNVKNGRV--LQAGCIFN----ISLGFGNLINPHPKNNYALLLIDTE 405
|
170 180
....*....|....*....|.
gi 1958791399 399 VVTQDSPLILSaDCPKEVNDI 419
Cdd:COG5406 406 QISLSNPIVFT-DSPKAQGDI 425
|
|
| PRK12897 |
PRK12897 |
type I methionyl aminopeptidase; |
312-409 |
2.05e-03 |
|
type I methionyl aminopeptidase;
Pssm-ID: 171806 Cd Length: 248 Bit Score: 39.63 E-value: 2.05e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958791399 312 LMGQKLKDLGIIKTS--KESAFKAARKYcphhVGHYLGMDVHDTPDM------PRSLPLQPGMVITVEP----GIYIPEG 379
Cdd:PRK12897 138 VIGNRVGDIGYAIESyvANEGFSVARDF----TGHGIGKEIHEEPAIfhfgkqGQGPELQEGMVITIEPivnvGMRYSKV 213
|
90 100 110
....*....|....*....|....*....|...
gi 1958791399 380 DTD--APEKFRG-LGVRIEDDVVVTQDSPLILS 409
Cdd:PRK12897 214 DLNgwTARTMDGkLSAQYEHTIAITKDGPIILT 246
|
|
|