NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|1958647550|ref|XP_038938819|]
View 

katanin-interacting protein isoform X6 [Rattus norvegicus]

Protein Classification

KATNIP family protein( domain architecture ID 10384633)

KATNIP family protein is a DUF4457 domain-containing protein; similar to Homo sapiens katanin-interacting protein (KATNIP, also known as KIAA0556), which is a ciliary basal body component, and may influence the stability of microtubules (MT), possibly through interaction with the MT-severing katanin complex

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
DUF4457 pfam14652
Domain of unknown function (DUF4457); This family of proteins is found in eukaryotes. It is ...
 1017-1336 0e+00

Domain of unknown function (DUF4457); This family of proteins is found in eukaryotes. It is found repeated several times in the vertebrate KIAA0556 proteins.


:

Pssm-ID: 464238  Cd Length: 323  Bit Score: 610.43  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958647550 1017 LNFTASWGDLHYIGLTGLEVVGKDGEALPIQPQQLSASPRDLNDLPEYSDDSRTLDKLIDGMNITTEDEHMWLIPFSPGL 1096
Cdd:pfam14652    1 LNFLSTWGDRHYLGLTGLEVLGEDGKAIPIQLSNITASPRDLNDLPGYSGDYRTLDKLIDGTNVTTDDEHMWLIPFSPGK 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958647550 1097 DHVVMIHFDRAQSIAGLRLWNYNKSPEDTYRGVKIAHVSLDGLCVSPAEGFLIRKGPGNCHFDFAQEILFG--DYLQTRL 1174
Cdd:pfam14652   81 EHTLTIDFGKPTSISGLRIWNYNKSLEDTYRGAKKVSVSLDGVVISPPEGFLLRKAPGNCHFDFAQTISFPnvDKVNPPS 160

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958647550 1175 PPAPSR-RLDAKSLERASMDYEAPLMPCGFIFQFQLLSSWGDPYYIGLTGLELYDEHGERIPLSQNNIAAFPDSVNALEG 1253
Cdd:pfam14652  161 KQSESQlRSSSKCSSQASQDYETPLMPCGFIFKFQLLSTWGDPYYIGLNGLELYDENGELIPLTENNIAAFPDSVNVLDG 240

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958647550 1254 VCGDVRTPDKLIDQVNDTSDGRHMWLAPILPGLVNRVYVIFDLPTTVSMIKLWNYTKTPQRGVKEFGLLVDDLLVYNGIL 1333
Cdd:pfam14652  241 VSGDVRTPDKLIDGVNNTNDGRHMWLAPILPGLVNRIYVIFDQPITVSMIKIWNYSKTPSRGVKEFAILVDDLLIYNGIL 320


                   ...
gi 1958647550 1334 AMV 1336
Cdd:pfam14652  321 RKA 323
DUF4457 super family cl20613
Domain of unknown function (DUF4457); This family of proteins is found in eukaryotes. It is ...
 767-911 9.41e-37

Domain of unknown function (DUF4457); This family of proteins is found in eukaryotes. It is found repeated several times in the vertebrate KIAA0556 proteins.


The actual alignment was detected with superfamily member pfam14652:

Pssm-ID: 464238  Cd Length: 323  Bit Score: 142.03  E-value: 9.41e-37
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958647550  767 DFKIPVLPYGQHLVIDIKSTWGDRHYVGLNGIEIFSSSGEPVQI--SSITADPPDINILPAYGKDPRVVSNLIDGVNRTQ 844
Cdd:pfam14652  180 DYETPLMPCGFIFKFQLLSTWGDPYYIGLNGLELYDENGELIPLteNNIAAFPDSVNVLDGVSGDVRTPDKLIDGVNNTN 259

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1958647550  845 DDMHVWLAPFTPGMTHTISIEFTHPCQVALIRIWNYNKSrihSFRGVKDITMLLDTQCIFEGEIAKA 911
Cdd:pfam14652  260 DGRHMWLAPILPGLVNRIYVIFDQPITVSMIKIWNYSKT---PSRGVKEFAILVDDLLIYNGILRKA 323
 
Name Accession Description Interval E-value
DUF4457 pfam14652
Domain of unknown function (DUF4457); This family of proteins is found in eukaryotes. It is ...
 1017-1336 0e+00

Domain of unknown function (DUF4457); This family of proteins is found in eukaryotes. It is found repeated several times in the vertebrate KIAA0556 proteins.


Pssm-ID: 464238  Cd Length: 323  Bit Score: 610.43  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958647550 1017 LNFTASWGDLHYIGLTGLEVVGKDGEALPIQPQQLSASPRDLNDLPEYSDDSRTLDKLIDGMNITTEDEHMWLIPFSPGL 1096
Cdd:pfam14652    1 LNFLSTWGDRHYLGLTGLEVLGEDGKAIPIQLSNITASPRDLNDLPGYSGDYRTLDKLIDGTNVTTDDEHMWLIPFSPGK 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958647550 1097 DHVVMIHFDRAQSIAGLRLWNYNKSPEDTYRGVKIAHVSLDGLCVSPAEGFLIRKGPGNCHFDFAQEILFG--DYLQTRL 1174
Cdd:pfam14652   81 EHTLTIDFGKPTSISGLRIWNYNKSLEDTYRGAKKVSVSLDGVVISPPEGFLLRKAPGNCHFDFAQTISFPnvDKVNPPS 160

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958647550 1175 PPAPSR-RLDAKSLERASMDYEAPLMPCGFIFQFQLLSSWGDPYYIGLTGLELYDEHGERIPLSQNNIAAFPDSVNALEG 1253
Cdd:pfam14652  161 KQSESQlRSSSKCSSQASQDYETPLMPCGFIFKFQLLSTWGDPYYIGLNGLELYDENGELIPLTENNIAAFPDSVNVLDG 240

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958647550 1254 VCGDVRTPDKLIDQVNDTSDGRHMWLAPILPGLVNRVYVIFDLPTTVSMIKLWNYTKTPQRGVKEFGLLVDDLLVYNGIL 1333
Cdd:pfam14652  241 VSGDVRTPDKLIDGVNNTNDGRHMWLAPILPGLVNRIYVIFDQPITVSMIKIWNYSKTPSRGVKEFAILVDDLLIYNGIL 320


                   ...
gi 1958647550 1334 AMV 1336
Cdd:pfam14652  321 RKA 323
DUF4457 pfam14652
Domain of unknown function (DUF4457); This family of proteins is found in eukaryotes. It is ...
 767-911 9.41e-37

Domain of unknown function (DUF4457); This family of proteins is found in eukaryotes. It is found repeated several times in the vertebrate KIAA0556 proteins.


Pssm-ID: 464238  Cd Length: 323  Bit Score: 142.03  E-value: 9.41e-37
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958647550  767 DFKIPVLPYGQHLVIDIKSTWGDRHYVGLNGIEIFSSSGEPVQI--SSITADPPDINILPAYGKDPRVVSNLIDGVNRTQ 844
Cdd:pfam14652  180 DYETPLMPCGFIFKFQLLSTWGDPYYIGLNGLELYDENGELIPLteNNIAAFPDSVNVLDGVSGDVRTPDKLIDGVNNTN 259

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1958647550  845 DDMHVWLAPFTPGMTHTISIEFTHPCQVALIRIWNYNKSrihSFRGVKDITMLLDTQCIFEGEIAKA 911
Cdd:pfam14652  260 DGRHMWLAPILPGLVNRIYVIFDQPITVSMIKIWNYSKT---PSRGVKEFAILVDDLLIYNGILRKA 323
 
Name Accession Description Interval E-value
DUF4457 pfam14652
Domain of unknown function (DUF4457); This family of proteins is found in eukaryotes. It is ...
 1017-1336 0e+00

Domain of unknown function (DUF4457); This family of proteins is found in eukaryotes. It is found repeated several times in the vertebrate KIAA0556 proteins.


Pssm-ID: 464238  Cd Length: 323  Bit Score: 610.43  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958647550 1017 LNFTASWGDLHYIGLTGLEVVGKDGEALPIQPQQLSASPRDLNDLPEYSDDSRTLDKLIDGMNITTEDEHMWLIPFSPGL 1096
Cdd:pfam14652    1 LNFLSTWGDRHYLGLTGLEVLGEDGKAIPIQLSNITASPRDLNDLPGYSGDYRTLDKLIDGTNVTTDDEHMWLIPFSPGK 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958647550 1097 DHVVMIHFDRAQSIAGLRLWNYNKSPEDTYRGVKIAHVSLDGLCVSPAEGFLIRKGPGNCHFDFAQEILFG--DYLQTRL 1174
Cdd:pfam14652   81 EHTLTIDFGKPTSISGLRIWNYNKSLEDTYRGAKKVSVSLDGVVISPPEGFLLRKAPGNCHFDFAQTISFPnvDKVNPPS 160

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958647550 1175 PPAPSR-RLDAKSLERASMDYEAPLMPCGFIFQFQLLSSWGDPYYIGLTGLELYDEHGERIPLSQNNIAAFPDSVNALEG 1253
Cdd:pfam14652  161 KQSESQlRSSSKCSSQASQDYETPLMPCGFIFKFQLLSTWGDPYYIGLNGLELYDENGELIPLTENNIAAFPDSVNVLDG 240

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958647550 1254 VCGDVRTPDKLIDQVNDTSDGRHMWLAPILPGLVNRVYVIFDLPTTVSMIKLWNYTKTPQRGVKEFGLLVDDLLVYNGIL 1333
Cdd:pfam14652  241 VSGDVRTPDKLIDGVNNTNDGRHMWLAPILPGLVNRIYVIFDQPITVSMIKIWNYSKTPSRGVKEFAILVDDLLIYNGIL 320


                   ...
gi 1958647550 1334 AMV 1336
Cdd:pfam14652  321 RKA 323
DUF4457 pfam14652
Domain of unknown function (DUF4457); This family of proteins is found in eukaryotes. It is ...
 767-911 9.41e-37

Domain of unknown function (DUF4457); This family of proteins is found in eukaryotes. It is found repeated several times in the vertebrate KIAA0556 proteins.


Pssm-ID: 464238  Cd Length: 323  Bit Score: 142.03  E-value: 9.41e-37
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958647550  767 DFKIPVLPYGQHLVIDIKSTWGDRHYVGLNGIEIFSSSGEPVQI--SSITADPPDINILPAYGKDPRVVSNLIDGVNRTQ 844
Cdd:pfam14652  180 DYETPLMPCGFIFKFQLLSTWGDPYYIGLNGLELYDENGELIPLteNNIAAFPDSVNVLDGVSGDVRTPDKLIDGVNNTN 259

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1958647550  845 DDMHVWLAPFTPGMTHTISIEFTHPCQVALIRIWNYNKSrihSFRGVKDITMLLDTQCIFEGEIAKA 911
Cdd:pfam14652  260 DGRHMWLAPILPGLVNRIYVIFDQPITVSMIKIWNYSKT---PSRGVKEFAILVDDLLIYNGILRKA 323
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH