2 ' -5 ' oligoadenylate synthetase 1F isoform X1 [Rattus norvegicus]
Protein Classification
OAS1_C domain-containing protein( domain architecture ID 10564343)
OAS1_C domain-containing protein
List of domain hits
| Name | Accession | Description | Interval | E-value | ||||
| OAS1_C | pfam10421 | 2'-5'-oligoadenylate synthetase 1, domain 2, C-terminus; This is the largely alpha-helical, ... |
31-220 | 9.04e-131 | ||||
2'-5'-oligoadenylate synthetase 1, domain 2, C-terminus; This is the largely alpha-helical, C-terminal half of 2'-5'-oligoadenylate synthetase 1, being described as domain 2 of the enzyme and homologous to a tandem ubiquitin repeat. It carries the region of enzymic activity between 320 and 344 at the extreme C-terminal end. Oligoadenylate synthetases are antiviral enzymes that counteract vial attack by degrading viral RNA. The enzyme uses ATP in 2'-specific nucleotidyl transfer reactions to synthesize 2'.5'-oligoadenylates, which activate latent ribonuclease, resulting in degradation of viral RNA and inhibition of virus replication. This domain is often associated with NTP_transf_2 pfam01909. : Pssm-ID: 463087 Cd Length: 188 Bit Score: 366.04 E-value: 9.04e-131
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| Name | Accession | Description | Interval | E-value | ||||
| OAS1_C | pfam10421 | 2'-5'-oligoadenylate synthetase 1, domain 2, C-terminus; This is the largely alpha-helical, ... |
31-220 | 9.04e-131 | ||||
2'-5'-oligoadenylate synthetase 1, domain 2, C-terminus; This is the largely alpha-helical, C-terminal half of 2'-5'-oligoadenylate synthetase 1, being described as domain 2 of the enzyme and homologous to a tandem ubiquitin repeat. It carries the region of enzymic activity between 320 and 344 at the extreme C-terminal end. Oligoadenylate synthetases are antiviral enzymes that counteract vial attack by degrading viral RNA. The enzyme uses ATP in 2'-specific nucleotidyl transfer reactions to synthesize 2'.5'-oligoadenylates, which activate latent ribonuclease, resulting in degradation of viral RNA and inhibition of virus replication. This domain is often associated with NTP_transf_2 pfam01909. Pssm-ID: 463087 Cd Length: 188 Bit Score: 366.04 E-value: 9.04e-131
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| Name | Accession | Description | Interval | E-value | ||||
| OAS1_C | pfam10421 | 2'-5'-oligoadenylate synthetase 1, domain 2, C-terminus; This is the largely alpha-helical, ... |
31-220 | 9.04e-131 | ||||
2'-5'-oligoadenylate synthetase 1, domain 2, C-terminus; This is the largely alpha-helical, C-terminal half of 2'-5'-oligoadenylate synthetase 1, being described as domain 2 of the enzyme and homologous to a tandem ubiquitin repeat. It carries the region of enzymic activity between 320 and 344 at the extreme C-terminal end. Oligoadenylate synthetases are antiviral enzymes that counteract vial attack by degrading viral RNA. The enzyme uses ATP in 2'-specific nucleotidyl transfer reactions to synthesize 2'.5'-oligoadenylates, which activate latent ribonuclease, resulting in degradation of viral RNA and inhibition of virus replication. This domain is often associated with NTP_transf_2 pfam01909. Pssm-ID: 463087 Cd Length: 188 Bit Score: 366.04 E-value: 9.04e-131
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| Blast search parameters | ||||
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