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Conserved domains on  [gi|1958680797|ref|XP_038949516|]
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tubulin polymerization-promoting protein family member 2 isoform X4 [Rattus norvegicus]

Protein Classification

tubulin polymerization-promoting family protein( domain architecture ID 10527554)

tubulin polymerization-promoting family protein similar to human tubulin polymerization-promoting protein (TPPP), a regulator of microtubule dynamics that plays a key role in myelination by promoting elongation of the myelin sheath

CATH:  1.10.238.10
EC:  3.6.5.-
Gene Ontology:  GO:0015631|GO:0046785|GO:0001578|GO:0000226
PubMed:  17105200
SCOP:  4001297

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
p25-alpha pfam05517
p25-alpha; This family encodes a 25 kDa protein that is phosphorylated by a Ser/Thr-Pro kinase. ...
 7-105 1.70e-46

p25-alpha; This family encodes a 25 kDa protein that is phosphorylated by a Ser/Thr-Pro kinase. It has been described as a brain specific protein, but it is found in Tetrahymena thermophila.


:

Pssm-ID: 461670  Cd Length: 155  Bit Score: 148.57  E-value: 1.70e-46
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958680797   7 VKAKNARTINFQQFQEAMKELGQKRFKGKNPDEALEDVFKLMEGKDPATTGATKATTVGGVDRLTDTSKYTGTHKERFDE 86
Cdd:pfam05517  51 VKAKSARTITFEQFKEALEELAEKRFKKKVKEEELELIEKLIEGKGPATTGVTKATKAGAVDRLTDTSKYTGSHKERFDE 130

                          90
                  ....*....|....*....
gi 1958680797  87 SGKGKGIEGREETTDNSGY 105
Cdd:pfam05517 131 SGKGKGIAGREDRVDNSGY 149
 
Name Accession Description Interval E-value
p25-alpha pfam05517
p25-alpha; This family encodes a 25 kDa protein that is phosphorylated by a Ser/Thr-Pro kinase. ...
 7-105 1.70e-46

p25-alpha; This family encodes a 25 kDa protein that is phosphorylated by a Ser/Thr-Pro kinase. It has been described as a brain specific protein, but it is found in Tetrahymena thermophila.


Pssm-ID: 461670  Cd Length: 155  Bit Score: 148.57  E-value: 1.70e-46
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958680797   7 VKAKNARTINFQQFQEAMKELGQKRFKGKNPDEALEDVFKLMEGKDPATTGATKATTVGGVDRLTDTSKYTGTHKERFDE 86
Cdd:pfam05517  51 VKAKSARTITFEQFKEALEELAEKRFKKKVKEEELELIEKLIEGKGPATTGVTKATKAGAVDRLTDTSKYTGSHKERFDE 130

                          90
                  ....*....|....*....
gi 1958680797  87 SGKGKGIEGREETTDNSGY 105
Cdd:pfam05517 131 SGKGKGIAGREDRVDNSGY 149
 
Name Accession Description Interval E-value
p25-alpha pfam05517
p25-alpha; This family encodes a 25 kDa protein that is phosphorylated by a Ser/Thr-Pro kinase. ...
 7-105 1.70e-46

p25-alpha; This family encodes a 25 kDa protein that is phosphorylated by a Ser/Thr-Pro kinase. It has been described as a brain specific protein, but it is found in Tetrahymena thermophila.


Pssm-ID: 461670  Cd Length: 155  Bit Score: 148.57  E-value: 1.70e-46
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958680797   7 VKAKNARTINFQQFQEAMKELGQKRFKGKNPDEALEDVFKLMEGKDPATTGATKATTVGGVDRLTDTSKYTGTHKERFDE 86
Cdd:pfam05517  51 VKAKSARTITFEQFKEALEELAEKRFKKKVKEEELELIEKLIEGKGPATTGVTKATKAGAVDRLTDTSKYTGSHKERFDE 130

                          90
                  ....*....|....*....
gi 1958680797  87 SGKGKGIEGREETTDNSGY 105
Cdd:pfam05517 131 SGKGKGIAGREDRVDNSGY 149
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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