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Conserved domains on  [gi|1958736535|ref|XP_038952388|]
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dnaJ homolog subfamily C member 1 isoform X2 [Rattus norvegicus]

Protein Classification

SANT/Myb-like DNA-binding domain-containing protein( domain architecture ID 10073748)

SANT (SWI3, ADA2, N-CoR and TFIIIB)/Myb-like DNA-binding domain-containing protein binds DNA and may function as a transcription factor

CATH:  1.20.58.1880
Gene Ontology:  GO:0006355|GO:0003677|GO:0003700
PubMed:  8882580|15040448|16877755
SCOP:  4000317

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
SANT cd00167
'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric ...
 269-316 1.47e-07

'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is also found in regulatory transcriptional repressor complexes where it also binds DNA.


:

Pssm-ID: 238096 [Multi-domain]  Cd Length: 45  Bit Score: 47.18  E-value: 1.47e-07
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*...
gi 1958736535 269 AWTQSQQKLLELALQQYPKGasdRWDKIAKCVPSKSKEDCIARYKLLV 316
Cdd:cd00167     1 PWTEEEDELLLEAVKKYGKN---NWEKIAKELPGRTPKQCRERWRNLL 45
SANT cd00167
'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric ...
 100-146 5.36e-03

'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is also found in regulatory transcriptional repressor complexes where it also binds DNA.


:

Pssm-ID: 238096 [Multi-domain]  Cd Length: 45  Bit Score: 34.47  E-value: 5.36e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*...
gi 1958736535 100 EWTEEDLSQLTRSMVKFPggtPGRWEKIAHELG-RSVTDVTTKAKELK 146
Cdd:cd00167     1 PWTEEEDELLLEAVKKYG---KNNWEKIAKELPgRTPKQCRERWRNLL 45
 
Name Accession Description Interval E-value
SANT cd00167
'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric ...
 269-316 1.47e-07

'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is also found in regulatory transcriptional repressor complexes where it also binds DNA.


Pssm-ID: 238096 [Multi-domain]  Cd Length: 45  Bit Score: 47.18  E-value: 1.47e-07
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*...
gi 1958736535 269 AWTQSQQKLLELALQQYPKGasdRWDKIAKCVPSKSKEDCIARYKLLV 316
Cdd:cd00167     1 PWTEEEDELLLEAVKKYGKN---NWEKIAKELPGRTPKQCRERWRNLL 45
SANT smart00717
SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains;
268-317 2.39e-06

SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains;


Pssm-ID: 197842 [Multi-domain]  Cd Length: 49  Bit Score: 43.75  E-value: 2.39e-06
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|
gi 1958736535  268 DAWTQSQQKLLELALQQYPKGasdRWDKIAKCVPSKSKEDCIARYKLLVE 317
Cdd:smart00717   2 GEWTEEEDELLIELVKKYGKN---NWEKIAKELPGRTAEQCRERWRNLLK 48
Myb_DNA-binding pfam00249
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, ...
 269-312 2.44e-05

Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, as well as the SANT domain family.


Pssm-ID: 459731 [Multi-domain]  Cd Length: 46  Bit Score: 40.95  E-value: 2.44e-05
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....
gi 1958736535 269 AWTQSQQKLLELALQQYPKgasdRWDKIAKCVPSKSKEDCIARY 312
Cdd:pfam00249   3 PWTPEEDELLLEAVEKLGN----RWKKIAKLLPGRTDNQCKNRW 42
RSC8 COG5259
RSC chromatin remodeling complex subunit RSC8 [Chromatin structure and dynamics / ...
 248-312 6.37e-04

RSC chromatin remodeling complex subunit RSC8 [Chromatin structure and dynamics / Transcription];


Pssm-ID: 227584 [Multi-domain]  Cd Length: 531  Bit Score: 41.41  E-value: 6.37e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1958736535 248 EQNDSSDEERPRKERSRAAEDAWT-QSQQKLLElALQQYpkgaSDRWDKIAKCVPSKSKEDCIARY 312
Cdd:COG5259   260 PSEFTSSDFKPVTISLLIRDKNWSrQELLLLLE-GIEMY----GDDWDKVARHVGTKTKEQCILHF 320
SANT cd00167
'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric ...
 100-146 5.36e-03

'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is also found in regulatory transcriptional repressor complexes where it also binds DNA.


Pssm-ID: 238096 [Multi-domain]  Cd Length: 45  Bit Score: 34.47  E-value: 5.36e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*...
gi 1958736535 100 EWTEEDLSQLTRSMVKFPggtPGRWEKIAHELG-RSVTDVTTKAKELK 146
Cdd:cd00167     1 PWTEEEDELLLEAVKKYG---KNNWEKIAKELPgRTPKQCRERWRNLL 45
 
Name Accession Description Interval E-value
SANT cd00167
'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric ...
 269-316 1.47e-07

'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is also found in regulatory transcriptional repressor complexes where it also binds DNA.


Pssm-ID: 238096 [Multi-domain]  Cd Length: 45  Bit Score: 47.18  E-value: 1.47e-07
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*...
gi 1958736535 269 AWTQSQQKLLELALQQYPKGasdRWDKIAKCVPSKSKEDCIARYKLLV 316
Cdd:cd00167     1 PWTEEEDELLLEAVKKYGKN---NWEKIAKELPGRTPKQCRERWRNLL 45
SANT smart00717
SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains;
268-317 2.39e-06

SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains;


Pssm-ID: 197842 [Multi-domain]  Cd Length: 49  Bit Score: 43.75  E-value: 2.39e-06
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|
gi 1958736535  268 DAWTQSQQKLLELALQQYPKGasdRWDKIAKCVPSKSKEDCIARYKLLVE 317
Cdd:smart00717   2 GEWTEEEDELLIELVKKYGKN---NWEKIAKELPGRTAEQCRERWRNLLK 48
Myb_DNA-binding pfam00249
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, ...
 269-312 2.44e-05

Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, as well as the SANT domain family.


Pssm-ID: 459731 [Multi-domain]  Cd Length: 46  Bit Score: 40.95  E-value: 2.44e-05
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....
gi 1958736535 269 AWTQSQQKLLELALQQYPKgasdRWDKIAKCVPSKSKEDCIARY 312
Cdd:pfam00249   3 PWTPEEDELLLEAVEKLGN----RWKKIAKLLPGRTDNQCKNRW 42
RSC8 COG5259
RSC chromatin remodeling complex subunit RSC8 [Chromatin structure and dynamics / ...
 248-312 6.37e-04

RSC chromatin remodeling complex subunit RSC8 [Chromatin structure and dynamics / Transcription];


Pssm-ID: 227584 [Multi-domain]  Cd Length: 531  Bit Score: 41.41  E-value: 6.37e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1958736535 248 EQNDSSDEERPRKERSRAAEDAWT-QSQQKLLElALQQYpkgaSDRWDKIAKCVPSKSKEDCIARY 312
Cdd:COG5259   260 PSEFTSSDFKPVTISLLIRDKNWSrQELLLLLE-GIEMY----GDDWDKVARHVGTKTKEQCILHF 320
SANT cd00167
'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric ...
 100-146 5.36e-03

'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is also found in regulatory transcriptional repressor complexes where it also binds DNA.


Pssm-ID: 238096 [Multi-domain]  Cd Length: 45  Bit Score: 34.47  E-value: 5.36e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*...
gi 1958736535 100 EWTEEDLSQLTRSMVKFPggtPGRWEKIAHELG-RSVTDVTTKAKELK 146
Cdd:cd00167     1 PWTEEEDELLLEAVKKYG---KNNWEKIAKELPgRTPKQCRERWRNLL 45
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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