|
Name |
Accession |
Description |
Interval |
E-value |
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
119-636 |
4.33e-10 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 63.42 E-value: 4.33e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759145 119 KLQTELE-------------------------EQHKKEKLSLEEDKNQLQLELENLKQ---ALGDKLTSANQEIDRLQDL 170
Cdd:COG1196 217 ELKEELKeleaellllklreleaeleeleaelEELEAELEELEAELAELEAELEELRLeleELELELEEAQAEEYELLAE 296
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759145 171 VRKSEQGLGSAEGLIASLQDSQERLQSELDLTKGRLKETKDALLNVEAELQQERHEHEQTLATMKEEEK--LRVDRMAHD 248
Cdd:COG1196 297 LARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEalLEAEAELAE 376
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759145 249 LEIKWTENLRQECSKLRQELKLQHEEDKKCAMSQLLQLKEREKTAARDSWQKKVEDLLNQRhslgEALHKSINNISLLKQ 328
Cdd:COG1196 377 AEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEE----EEEEEALEEAAEEEA 452
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759145 329 NLELQLCQSQTSLQQLQAQFTQERQRLtQELEELEEQHQQRHKSLKEAHVLAFQTMEEEKEKEQRALETHLQQKHSAELQ 408
Cdd:COG1196 453 ELEEEEEALLELLAELLEEAALLEAAL-AELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIG 531
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759145 409 SLK-------DAHRESMEGFRVEMEQELQTLRFELEDEGKAMLASLRSELNHQHATSIDLLRHSHHQELAAAKMELERSI 481
Cdd:COG1196 532 VEAayeaaleAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREA 611
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759145 482 DISRRQSKEHMCRISDLQDELRHREHHITDLD---KEVQHLHESISTLTKELELKGKEILRIRSESNQQMRLHEQDLNKR 558
Cdd:COG1196 612 DARYYVLGDTLLGRTLVAARLEAALRRAVTLAgrlREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEE 691
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1958759145 559 LEKELDVMTADHLREKNIMRADFNKTNELLKEINAALQVSLEDMEEKYLMRESRPEDLQMIAELKSLLTERDQVIKKL 636
Cdd:COG1196 692 ELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELEREL 769
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
30-537 |
4.41e-07 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 53.79 E-value: 4.41e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759145 30 AQLAGHNMDYSQDMHLKMSKKIAQLTKKVNEVKRTQQ------EYYEMELKNLQTRLEGEVAQLNETHGKTLEELAWKHH 103
Cdd:COG1196 227 AELLLLKLRELEAELEELEAELEELEAELEELEAELAeleaelEELRLELEELELELEEAQAEEYELLAELARLEQDIAR 306
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759145 104 MAIEAvhSNASRDKIKLQTELEE------QHKKEKLSLEEDKNQLQLELENLKQALGDK-------LTSANQEIDRLQDL 170
Cdd:COG1196 307 LEERR--RELEERLEELEEELAEleeeleELEEELEELEEELEEAEEELEEAEAELAEAeealleaEAELAEAEEELEEL 384
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759145 171 VRKSEQGLGSAEGLIASLQDSQERLQSELDLTKGRLKETKDALLNVEAELQQERHEHEQTLATMKEEEKLRVDRMAHDLE 250
Cdd:COG1196 385 AEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLEL 464
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759145 251 IkwtENLRQECSKLRQELKLQHEEDKKCAMSQLLQLKEREKTAARDSWQKKVEDLLNQR--------------------- 309
Cdd:COG1196 465 L---AELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRglagavavligveaayeaale 541
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759145 310 HSLGEALHKSINN--------ISLLKQNLELQLCQSQTSLQQLQAQFTQERQRLTQELEELEEQHQQRHKSLKEAHV--- 378
Cdd:COG1196 542 AALAAALQNIVVEddevaaaaIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLgdt 621
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759145 379 LAFQTMEEE-KEKEQRALETHLQQKHSAELQSLKDAHRESMEGFRVEMEQELQTLRFELEDEGKAMLASLRSELNHQHAT 457
Cdd:COG1196 622 LLGRTLVAArLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLA 701
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759145 458 SIDLLRHSHHQELAAAKMELERSIDISRRQSKEHMCRISDLQDELRHREHHITDLDKEvqhlhESISTLTKELELKGKEI 537
Cdd:COG1196 702 EEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEP-----PDLEELERELERLEREI 776
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
77-604 |
4.44e-07 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 53.77 E-value: 4.44e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759145 77 QTRLEGEVAQLNETHGKTLEELAWKHHMAIEAVHSNASRDKIKLQTELEE------QHKKEKLSLEEDKNQLQLELENLK 150
Cdd:COG4913 250 QIELLEPIRELAERYAAARERLAELEYLRAALRLWFAQRRLELLEAELEElraelaRLEAELERLEARLDALREELDELE 329
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759145 151 QAL----GDKLTSANQEIDRLQDLVRKSEQGLGSAEGLIASLQDSQERLQSELDLTKGRLKETKDALLNVEAELQQERHE 226
Cdd:COG4913 330 AQIrgngGDRLEQLEREIERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAEAAALLEALEEELEALEEALAE 409
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759145 227 HEQTLATMKEEEKlrvdrmAHDLEIKWTE----NLRQECSKLRQELK--LQHEEDKKCAMSQLLQLKEREKtaardSWQK 300
Cdd:COG4913 410 AEAALRDLRRELR------ELEAEIASLErrksNIPARLLALRDALAeaLGLDEAELPFVGELIEVRPEEE-----RWRG 478
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759145 301 KVEDLL-NQRHSL-------GEALHKsINNISlLKQNLELQLCQSQTSLQQLQA-------------------------- 346
Cdd:COG4913 479 AIERVLgGFALTLlvppehyAAALRW-VNRLH-LRGRLVYERVRTGLPDPERPRldpdslagkldfkphpfrawleaelg 556
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759145 347 ------------QFTQERQRLTQELEELEEQHQQRH---KSLKEAHVLAFQTME--EEKEKEQRALETHLQQkHSAELQS 409
Cdd:COG4913 557 rrfdyvcvdspeELRRHPRAITRAGQVKGNGTRHEKddrRRIRSRYVLGFDNRAklAALEAELAELEEELAE-AEERLEA 635
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759145 410 LKDAHRESMEgfRVEMEQELQTLRFELED--EGKAMLASLRSELNHQHATSIDLlrhshhqelaaakMELERSIDISRRQ 487
Cdd:COG4913 636 LEAELDALQE--RREALQRLAEYSWDEIDvaSAEREIAELEAELERLDASSDDL-------------AALEEQLEELEAE 700
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759145 488 SKEHMCRISDLQDELRHREHHITDLDKEVQHLHESISTLTKELELKGKEILRIRSEsNQQMRLHEQDLNKRLEKELDVMT 567
Cdd:COG4913 701 LEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLEERFA-AALGDAVERELRENLEERIDALR 779
|
570 580 590
....*....|....*....|....*....|....*..
gi 1958759145 568 ADHLREKNIMRADFNKTNELLKEINAALQVSLEDMEE 604
Cdd:COG4913 780 ARLNRAEEELERAMRAFNREWPAETADLDADLESLPE 816
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
129-529 |
6.12e-07 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 53.14 E-value: 6.12e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759145 129 KKEKLSLEEDKNQLQLELENLKQALGD---KLTSANQEIDRLQDLVRKSEQGLGSAEGLIASLQDSQERLQSELDLTKGR 205
Cdd:TIGR02168 676 RREIEELEEKIEELEEKIAELEKALAElrkELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKE 755
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759145 206 LKETKDALLNVEAELQQERHEHEQTLATMKEEEKlRVDRMAHDLeikwtENLRQECSKLRQELKLQHEEdkkcamSQLLQ 285
Cdd:TIGR02168 756 LTELEAEIEELEERLEEAEEELAEAEAEIEELEA-QIEQLKEEL-----KALREALDELRAELTLLNEE------AANLR 823
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759145 286 LKEREKTAARDSWQKKVEDLLNQRHSL---GEALHKSINNISLLKQNLELQLcqsqtslqqlqAQFTQERQRLTQEleel 362
Cdd:TIGR02168 824 ERLESLERRIAATERRLEDLEEQIEELsedIESLAAEIEELEELIEELESEL-----------EALLNERASLEEA---- 888
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759145 363 eeqhqqrhksLKEAHVLAFQTMEEEKEKEQRALEthLQQKHSaELQSLKDAHRESMEGFRVEMEQELQTLRFELEDEGKA 442
Cdd:TIGR02168 889 ----------LALLRSELEELSEELRELESKRSE--LRRELE-ELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEE 955
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759145 443 MLAslrselnhqHATSIDLLRHSHHQELAAAKMELERSIDISRRQSKEhmcrISDLQDELRHREHHITDLDKEVQHLHES 522
Cdd:TIGR02168 956 AEA---------LENKIEDDEEEARRRLKRLENKIKELGPVNLAAIEE----YEELKERYDFLTAQKEDLTEAKETLEEA 1022
|
....*..
gi 1958759145 523 ISTLTKE 529
Cdd:TIGR02168 1023 IEEIDRE 1029
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
112-403 |
1.20e-06 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 52.37 E-value: 1.20e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759145 112 NASRDKIKLQTELEEQHKKEKLSLEEDKNQLQLELENLKQALGD---KLTSANQEIDRL-QDLVRKSEQglgsaeglIAS 187
Cdd:TIGR02168 242 EELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEElqkELYALANEISRLeQQKQILRER--------LAN 313
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759145 188 LQDSQERLQSELDLTKGRLKETKDALLNVEAELQQERHEHEQTLATMKEEEKLRvdRMAHDLEIKWTENLRQECSKLRqe 267
Cdd:TIGR02168 314 LERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAEL--EELESRLEELEEQLETLRSKVA-- 389
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759145 268 lklQHEEDKKCAMSQLLQLKEREK--TAARDSWQKKVEDLLNQRHSLgeALHKSINNISLLKQNLElqlcQSQTSLQQLQ 345
Cdd:TIGR02168 390 ---QLELQIASLNNEIERLEARLErlEDRRERLQQEIEELLKKLEEA--ELKELQAELEELEEELE----ELQEELERLE 460
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*...
gi 1958759145 346 AQFTQERQRLTQELEELEEQHQQRHKSLKEAHVLafQTMEEEKEKEQRALETHLQQKH 403
Cdd:TIGR02168 461 EALEELREELEEAEQALDAAERELAQLQARLDSL--ERLQENLEGFSEGVKALLKNQS 516
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
121-324 |
1.82e-06 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 50.92 E-value: 1.82e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759145 121 QTELEEQHKKEKLSLEEDKNQLQLELENLKQ---ALGDKLTSANQEIDRLQDLVRKSEQGLGSAEGLIASLQDSQERLQS 197
Cdd:COG4942 18 QADAAAEAEAELEQLQQEIAELEKELAALKKeekALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRA 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759145 198 ELDLTKGRLKETKDA------------LLNVEAELQQERheHEQTLATMKEEEKLRVDRMAHDLEIkwTENLRQECSKLR 265
Cdd:COG4942 98 ELEAQKEELAELLRAlyrlgrqpplalLLSPEDFLDAVR--RLQYLKYLAPARREQAEELRADLAE--LAALRAELEAER 173
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1958759145 266 QELKLQHEEDKKCAMSQLLQLKEREKTAAR-----DSWQKKVEDLLNQRHSLGEALHKSINNIS 324
Cdd:COG4942 174 AELEALLAELEEERAALEALKAERQKLLARlekelAELAAELAELQQEAEELEALIARLEAEAA 237
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
58-564 |
2.72e-06 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 51.27 E-value: 2.72e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759145 58 VNEVKRTQQEYYEMELKNLQT---RLEGEVAQLNETHGKTLEELAWKHHMA-IEAVHSNASRDKI---------KLQTEL 124
Cdd:pfam15921 304 IQEQARNQNSMYMRQLSDLEStvsQLRSELREAKRMYEDKIEELEKQLVLAnSELTEARTERDQFsqesgnlddQLQKLL 383
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759145 125 EEQHKKEK-LSLEEDKNQL--------QLELENLKQALGDKltsaNQEIDRLQDLVR--KSEqGLGSAEGLIASLQDSQE 193
Cdd:pfam15921 384 ADLHKREKeLSLEKEQNKRlwdrdtgnSITIDHLRRELDDR----NMEVQRLEALLKamKSE-CQGQMERQMAAIQGKNE 458
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759145 194 RLQSELDLTkGRLKETKDALLNVEAELQQERHEHEQTLATMKE-----EEKLRVdrmahdleikwTENLRQECSKLRQ-- 266
Cdd:pfam15921 459 SLEKVSSLT-AQLESTKEMLRKVVEELTAKKMTLESSERTVSDltaslQEKERA-----------IEATNAEITKLRSrv 526
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759145 267 ELKLQHEEDKKCAMSQL---------LQLKEREKTAARDSWQKKVED---LLNQRHSLGEALHKSINNISLLKQNLELQL 334
Cdd:pfam15921 527 DLKLQELQHLKNEGDHLrnvqteceaLKLQMAEKDKVIEILRQQIENmtqLVGQHGRTAGAMQVEKAQLEKEINDRRLEL 606
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759145 335 CQSQTSLQQLQAQFTQERQRLTQELEELEEQHQQRHKSLKeahvlAFQTMEEEKEKEQRALETHlqqkhSAELQSLKDAH 414
Cdd:pfam15921 607 QEFKILKDKKDAKIRELEARVSDLELEKVKLVNAGSERLR-----AVKDIKQERDQLLNEVKTS-----RNELNSLSEDY 676
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759145 415 RESMEGFRVEMEqELQTLRFELedegKAMLASLRSELNHQHATSIDLLRHSHHQELAAakMELERSIDISRRQskehmcr 494
Cdd:pfam15921 677 EVLKRNFRNKSE-EMETTTNKL----KMQLKSAQSELEQTRNTLKSMEGSDGHAMKVA--MGMQKQITAKRGQ------- 742
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1958759145 495 ISDLQDELRHREHHITDLDKEVQHLHESISTLTKELELKGKEILRIRSE----SNQQMRLHEQDLNkrLEKELD 564
Cdd:pfam15921 743 IDALQSKIQFLEEAMTNANKEKHFLKEEKNKLSQELSTVATEKNKMAGElevlRSQERRLKEKVAN--MEVALD 814
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
156-506 |
3.98e-06 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 50.32 E-value: 3.98e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759145 156 KLTSANQEIDRLQDLVRKSEQGLGS----AEglIA----SLQDSQERLQSELDLTKGRLKETKDALLNVEAELQQERHEH 227
Cdd:COG1196 180 KLEATEENLERLEDILGELERQLEPlerqAE--KAeryrELKEELKELEAELLLLKLRELEAELEELEAELEELEAELEE 257
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759145 228 EQTLATMKEEEKLRVDRMAHDLEIKWTENLRQECSKLRQELKLQHEEDKKCAMSQLLQLKEREKTAARDSWQKKVEDLLN 307
Cdd:COG1196 258 LEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEE 337
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759145 308 QRHSLGEALHKSINNISLLKQNL----ELQLCQSQTSLQQLQAQFTQERQRLTQELEELEEQHQQRHKSLKEAHVLAFQT 383
Cdd:COG1196 338 ELEELEEELEEAEEELEEAEAELaeaeEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLE 417
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759145 384 MEEEKEKEQRALETHLQQKHSAELQSLKDAHREsmegfRVEMEQELQTLRFELEDEGKAmLASLRSELNHQHATSIDLLR 463
Cdd:COG1196 418 RLEEELEELEEALAELEEEEEEEEEALEEAAEE-----EAELEEEEEALLELLAELLEE-AALLEAALAELLEELAEAAA 491
|
330 340 350 360
....*....|....*....|....*....|....*....|...
gi 1958759145 464 HSHHQELAAAKMELERSiDISRRQSKEHMCRISDLQDELRHRE 506
Cdd:COG1196 492 RLLLLLEAEADYEGFLE-GVKAALLLAGLRGLAGAVAVLIGVE 533
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
30-636 |
6.51e-06 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 49.68 E-value: 6.51e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759145 30 AQLAGHNMDYSQDMHLKMSKKIAQLTKKVNEVKRTQQEYyEMELKNLQTRLEGEVAQLNETHG------KTLEELAwKHH 103
Cdd:TIGR02169 275 EELNKKIKDLGEEEQLRVKEKIGELEAEIASLERSIAEK-ERELEDAEERLAKLEAEIDKLLAeieeleREIEEER-KRR 352
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759145 104 MAIEAVHSNASRDKIKLQTELEEQHKKEKLSLEEDKnQLQLELENLKqalgDKLTSANQEIDRLQDLVRKSEQGLGSAEG 183
Cdd:TIGR02169 353 DKLTEEYAELKEELEDLRAELEEVDKEFAETRDELK-DYREKLEKLK----REINELKRELDRLQEELQRLSEELADLNA 427
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759145 184 LIASLqdsqerlqseldltKGRLKETKDALLNVEAELQQERHEHEQTLATM-KEEEKLRvdrmahdleikwteNLRQECS 262
Cdd:TIGR02169 428 AIAGI--------------EAKINELEEEKEDKALEIKKQEWKLEQLAADLsKYEQELY--------------DLKEEYD 479
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759145 263 KLRQEL-KLQHEEDKKCAMSQLLQLKEREKTAARDSWQKKVEDLLNQRHSLGEALHKSINNISLLKQNLELQLCQSQTSL 341
Cdd:TIGR02169 480 RVEKELsKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQGVHGTVAQLGSVGERYATAIEVAAGNRLNNVVVEDDAV 559
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759145 342 QQLQAQFTQERQ--RLTQELEELEEQHQQRHKSLKEAHVLAFQTMEEEKEKEQRA--------------LETHLQQKHSA 405
Cdd:TIGR02169 560 AKEAIELLKRRKagRATFLPLNKMRDERRDLSILSEDGVIGFAVDLVEFDPKYEPafkyvfgdtlvvedIEAARRLMGKY 639
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759145 406 ELQSLK-------------DAHRESMEGFRVEMEQELQTLRFELEdEGKAMLASLRSELNHQHATSIDLLR-----HSHH 467
Cdd:TIGR02169 640 RMVTLEgelfeksgamtggSRAPRGGILFSRSEPAELQRLRERLE-GLKRELSSLQSELRRIENRLDELSQelsdaSRKI 718
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759145 468 QELAAAKMELERSIDISRRQSKEHMCRISDLQDELRHREHHITDLDKEVQHLHESISTLTKELE-----LKGKEILRIRS 542
Cdd:TIGR02169 719 GEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNdlearLSHSRIPEIQA 798
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759145 543 ESNQQMRLH----------EQDLNKR-LEKELdvmtADHLRE--KNIMRADFNKTNELLKEInAALQVSLEDMEEKylMR 609
Cdd:TIGR02169 799 ELSKLEEEVsriearlreiEQKLNRLtLEKEY----LEKEIQelQEQRIDLKEQIKSIEKEI-ENLNGKKEELEEE--LE 871
|
650 660
....*....|....*....|....*..
gi 1958759145 610 ESRPEDLQMIAELKSLLTERDQVIKKL 636
Cdd:TIGR02169 872 ELEAALRDLESRLGDLKKERDELEAQL 898
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
120-648 |
3.22e-05 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 47.66 E-value: 3.22e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759145 120 LQTELEEQHKKEKLSLEEDKNQLQLELENLKQALGDKLTSANQEIDRLQDLVRKSEQGLGSAEGLIASLQDSQERLQSEL 199
Cdd:TIGR00618 181 LALMEFAKKKSLHGKAELLTLRSQLLTLCTPCMPDTYHERKQVLEKELKHLREALQQTQQSHAYLTQKREAQEEQLKKQQ 260
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759145 200 DLTKGRLKETKDALLNVEAELQQERHEHEQTLATMKEEEK----LRVDRMAHDLEIKWTENLRQECSKLRQELKLQHEED 275
Cdd:TIGR00618 261 LLKQLRARIEELRAQEAVLEETQERINRARKAAPLAAHIKavtqIEQQAQRIHTELQSKMRSRAKLLMKRAAHVKQQSSI 340
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759145 276 KKCAMSQLLQLKEREKTAARDSWQKKVEDLLNQRHSLGEALHKSINNISLLKQNLEL--QLCQSQTSLQQLQAQFTQERQ 353
Cdd:TIGR00618 341 EEQRRLLQTLHSQEIHIRDAHEVATSIREISCQQHTLTQHIHTLQQQKTTLTQKLQSlcKELDILQREQATIDTRTSAFR 420
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759145 354 RLTQELEELEEQHQQRHKSLKEAHVLAFQTMEEEKEKE------QRALETHLQQKHSAELQSLKDAHRESMEGFRVEMEQ 427
Cdd:TIGR00618 421 DLQGQLAHAKKQQELQQRYAELCAAAITCTAQCEKLEKihlqesAQSLKEREQQLQTKEQIHLQETRKKAVVLARLLELQ 500
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759145 428 ELQTLRFELEDE-GKAMLASLRSELN-----------HQHATSIDLLRH------SHHQELAAAKMELERSIDISRRQSK 489
Cdd:TIGR00618 501 EEPCPLCGSCIHpNPARQDIDNPGPLtrrmqrgeqtyAQLETSEEDVYHqltserKQRASLKEQMQEIQQSFSILTQCDN 580
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759145 490 EHMCRISDLQDELRHREHHITDLDKEVQHLHEsistLTKELELKGKEILrirseSNQQMRLHEQDLNKRLEKELDVMTAD 569
Cdd:TIGR00618 581 RSKEDIPNLQNITVRLQDLTEKLSEAEDMLAC----EQHALLRKLQPEQ-----DLQDVRLHLQQCSQELALKLTALHAL 651
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759145 570 HLR-EKNIMRADFNKTNELLKEINAALQVSLEDMEEKYlmrESRPEDLQMIAELKSLLTERDQVIKKLieDNKFYQLELV 648
Cdd:TIGR00618 652 QLTlTQERVREHALSIRVLPKELLASRQLALQKMQSEK---EQLTYWKEMLAQCQTLLRELETHIEEY--DREFNEIENA 726
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
70-274 |
9.45e-05 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 45.53 E-value: 9.45e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759145 70 EMELKNLQTRL---EGEVAQLNETHGKTLEELAwkhhmAIEAVHSNASRDKIKLQTELEEQHKKEKlSLEEDKNQLQLEL 146
Cdd:COG4942 26 EAELEQLQQEIaelEKELAALKKEEKALLKQLA-----ALERRIAALARRIRALEQELAALEAELA-ELEKEIAELRAEL 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759145 147 ENLKQALGDKL------------------TSANQEIDRLQDLVRKSEQGLGSAEGLIASLQDsQERLQSELDLTKGRLKE 208
Cdd:COG4942 100 EAQKEELAELLralyrlgrqpplalllspEDFLDAVRRLQYLKYLAPARREQAEELRADLAE-LAALRAELEAERAELEA 178
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1958759145 209 TKDALLNVEAELQQERHEHEQTLATMKEEEKLRVDRMAHdlEIKWTENLRQECSKLRQELKLQHEE 274
Cdd:COG4942 179 LLAELEEERAALEALKAERQKLLARLEKELAELAAELAE--LQQEAEELEALIARLEAEAAAAAER 242
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
48-561 |
1.72e-04 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 45.34 E-value: 1.72e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759145 48 SKKIAQLTKKVNEVKRTQQEYYEMELKNLQTRLEGEVAQLNETHGKTLEE--LAWKHHMAIEAVHSNASRDKIKLQTELE 125
Cdd:TIGR00618 299 IKAVTQIEQQAQRIHTELQSKMRSRAKLLMKRAAHVKQQSSIEEQRRLLQtlHSQEIHIRDAHEVATSIREISCQQHTLT 378
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759145 126 EQHKKEKLSLEEDKNQLQL---ELENLKQALGDKLTSANQEIDRLQDLVRKSEQGLGSAEGLIASLQDSQERLQSE---- 198
Cdd:TIGR00618 379 QHIHTLQQQKTTLTQKLQSlckELDILQREQATIDTRTSAFRDLQGQLAHAKKQQELQQRYAELCAAAITCTAQCEklek 458
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759145 199 --LDLTKGRLKETKDALLNVEAELQQE---RHEHEQTLATMKEEEKLRVDRMAH-DLEIKWTENLRQECSKLRQELK--L 270
Cdd:TIGR00618 459 ihLQESAQSLKEREQQLQTKEQIHLQEtrkKAVVLARLLELQEEPCPLCGSCIHpNPARQDIDNPGPLTRRMQRGEQtyA 538
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759145 271 QHEEDKKCAMSQLLQLKEREK--TAARDSWQKKVEDLLNQRHSLGEALHKSINNISLLKQNLELQLCQSQTSLQQLQAQF 348
Cdd:TIGR00618 539 QLETSEEDVYHQLTSERKQRAslKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITVRLQDLTEKLSEAEDMLACEQHALL 618
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759145 349 TQERQRLTQELEELEEQHQQRHKSLKEAHVLAFQ-TMEEEKEKEQRALETHLQQKHSAELQSLKDA---HRESMEGFRVE 424
Cdd:TIGR00618 619 RKLQPEQDLQDVRLHLQQCSQELALKLTALHALQlTLTQERVREHALSIRVLPKELLASRQLALQKmqsEKEQLTYWKEM 698
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759145 425 MEQELQTLRFELEDEGKamlaslrselNHQHATSIDLLRHSHHQELAAAKMELERSIDISRRQSKEHMCRISDLQDELRH 504
Cdd:TIGR00618 699 LAQCQTLLRELETHIEE----------YDREFNEIENASSSLGSDLAAREDALNQSLKELMHQARTVLKARTEAHFNNNE 768
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|....*..
gi 1958759145 505 REHHITDLDKEVQHLHESISTLTKELELKGKEILRIRSESNQQMRLHEQDLNKRLEK 561
Cdd:TIGR00618 769 EVTAALQTGAELSHLAAEIQFFNRLREEDTHLLKTLEAEIGQEIPSDEDILNLQCET 825
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
218-562 |
1.73e-04 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 45.31 E-value: 1.73e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759145 218 AELQQERHEHEQTLATMKEEEkLRVDRMAHDLEiKWTENLRQECSKLRQELKLQHEEDKKCAMSQLLQLKEREKTAARDs 297
Cdd:COG1196 168 SKYKERKEEAERKLEATEENL-ERLEDILGELE-RQLEPLERQAEKAERYRELKEELKELEAELLLLKLRELEAELEEL- 244
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759145 298 wQKKVEDLLNQRhslgEALHKSINNISLLKQNLELQLcqsqTSLQQLQAQFTQERQRLTQELEELEEQHQQRHKSLKEAH 377
Cdd:COG1196 245 -EAELEELEAEL----EELEAELAELEAELEELRLEL----EELELELEEAQAEEYELLAELARLEQDIARLEERRRELE 315
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759145 378 VLAFQTMEEEKEKEQRALETHLQQKHSAELQSLKDAHRESMEGFRVEMEQELQTLRFELEDEGKAMLASLRSELNHQHAT 457
Cdd:COG1196 316 ERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAA 395
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759145 458 SIDLLRHSHHQELAAAKMELERSIDISRRQSKEhmcRISDLQDELRHREHHITDLDKEVQHLHESISTLTKELELKGKEI 537
Cdd:COG1196 396 AELAAQLEELEEAEEALLERLERLEEELEELEE---ALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEA 472
|
330 340
....*....|....*....|....*
gi 1958759145 538 LRIRSESNQQMRLHEQDLNKRLEKE 562
Cdd:COG1196 473 ALLEAALAELLEELAEAAARLLLLL 497
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
49-442 |
1.91e-04 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 45.13 E-value: 1.91e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759145 49 KKIAQLTKKVNEVKRTQQEYYEMELKNLQTRLEG------EVAQLNETHGKTLEELAWKHHMAIEAVHSNASRDKIKLQT 122
Cdd:PTZ00121 1335 KKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAaekkkeEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAA 1414
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759145 123 ELEEQHKKEKLSLEEDKNQLQLELENLKQALGDKLTSANQEIDRLQDLVRKSEQGLGSAEGLIAS--------LQDSQER 194
Cdd:PTZ00121 1415 AAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAeeakkadeAKKKAEE 1494
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759145 195 LQSELDLTKGRLKETKDALLNVEAELQQERHEHEQTLATMKEEEKLRVDRMAHDLEIKWTENLRQECSKLRQELKLQHEE 274
Cdd:PTZ00121 1495 AKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEE 1574
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759145 275 DKKCAMSQLLQLKEREKTAARDSWQKKVEDLLNQRHSLGEALHKSINNISLLKQNLELQLCQSQTSLQQLQAQFTQERQR 354
Cdd:PTZ00121 1575 DKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKK 1654
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759145 355 LTQELEELEEQHQQRHKSLKEAHVLAFQTMEEEKEKEQRALETHLQQKHSAELQSLKDAHRESMEGFRVEMEQEL----Q 430
Cdd:PTZ00121 1655 AEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKikaeE 1734
|
410
....*....|..
gi 1958759145 431 TLRFELEDEGKA 442
Cdd:PTZ00121 1735 AKKEAEEDKKKA 1746
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
346-638 |
3.73e-04 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 44.28 E-value: 3.73e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759145 346 AQFTQERQRLTQELEELEEQHQQRHKSLkEAHVLAFQTMEEEKEKEQRALETHLQQKHSAELQ------SLKDAHR--ES 417
Cdd:TIGR02168 242 EELQEELKEAEEELEELTAELQELEEKL-EELRLEVSELEEEIEELQKELYALANEISRLEQQkqilreRLANLERqlEE 320
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759145 418 MEGFRVEMEQELQTLRFELED--EGKAMLASLRSELNHQHATSIDLLrhshhQELAAAKMELERSIDISRRQSKEHMCRI 495
Cdd:TIGR02168 321 LEAQLEELESKLDELAEELAEleEKLEELKEELESLEAELEELEAEL-----EELESRLEELEEQLETLRSKVAQLELQI 395
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759145 496 SDLQDELRHREHHITDLDKEVQHLHESISTLTKELELKGKEILRIRSESNQQMRLHEQDLNKRLEKELDvmTADHLREKN 575
Cdd:TIGR02168 396 ASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALE--ELREELEEA 473
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1958759145 576 imRADFNKTNELLKEINAALQvSLEDMEEKYlmrESRPEDLQMIAELKSLLTERDQVIKKLIE 638
Cdd:TIGR02168 474 --EQALDAAERELAQLQARLD-SLERLQENL---EGFSEGVKALLKNQSGLSGILGVLSELIS 530
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
156-453 |
4.69e-04 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 43.89 E-value: 4.69e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759145 156 KLTSANQEIDRLQDLVRKSEQGLGS----AEGLIASLQDSQERLQSELDLTKGRLKETK---DALLNVEAELQQERHEHE 228
Cdd:TIGR02168 180 KLERTRENLDRLEDILNELERQLKSlerqAEKAERYKELKAELRELELALLVLRLEELReelEELQEELKEAEEELEELT 259
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759145 229 QTLATMKEE------EKLRVDRMAHDLEIKWtENLRQECSKLRQELKLQHEE------DKKCAMSQLLQLKEREKTAARD 296
Cdd:TIGR02168 260 AELQELEEKleelrlEVSELEEEIEELQKEL-YALANEISRLEQQKQILRERlanlerQLEELEAQLEELESKLDELAEE 338
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759145 297 --SWQKKVEDLLNQRHSL---GEALHKSINNISLLKQNLELQLCQSQTSLQQLQAQFTQERQRLTQELEELEEQHQQRHK 371
Cdd:TIGR02168 339 laELEEKLEELKEELESLeaeLEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRER 418
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759145 372 SLKEAHVLAFQTMEEEKEKEQRALETHLQQKHsaELQSLKDAHR---ESMEGFRVEMEQELQTLRFELEdEGKAMLASLR 448
Cdd:TIGR02168 419 LQQEIEELLKKLEEAELKELQAELEELEEELE--ELQEELERLEealEELREELEEAEQALDAAERELA-QLQARLDSLE 495
|
....*
gi 1958759145 449 SELNH 453
Cdd:TIGR02168 496 RLQEN 500
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
49-649 |
7.58e-04 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 43.18 E-value: 7.58e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759145 49 KKIAQLTKKVNEVKRTQQEYYEMELKNLQTRLE------GEVAQLNETHGKTLEELAWKHHMAIEAVHSNAS--RDKIKL 120
Cdd:pfam15921 88 KDLQRRLNESNELHEKQKFYLRQSVIDLQTKLQemqmerDAMADIRRRESQSQEDLRNQLQNTVHELEAAKClkEDMLED 167
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759145 121 QTELEEQHKKEKLSLEEDKNQLQLELENLKQALGDKLtsanQEIDRLQDLVRKSeqgLGSAEGLIAslqdsqERLQSELD 200
Cdd:pfam15921 168 SNTQIEQLRKMMLSHEGVLQEIRSILVDFEEASGKKI----YEHDSMSTMHFRS---LGSAISKIL------RELDTEIS 234
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759145 201 LTKGRlketkdaLLNVEAELQQERHEHEQTLATMKEEEKLRVDRMAHDLEIKWT------ENLRQECSKLRQELKLQHEE 274
Cdd:pfam15921 235 YLKGR-------IFPVEDQLEALKSESQNKIELLLQQHQDRIEQLISEHEVEITgltekaSSARSQANSIQSQLEIIQEQ 307
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759145 275 DKKCAMSQLLQLKEREKTAARdswqkkvedllnQRHSLGEALHKSINNISLLKQNLELQlCQSQTSLQQLQAQFTQERQR 354
Cdd:pfam15921 308 ARNQNSMYMRQLSDLESTVSQ------------LRSELREAKRMYEDKIEELEKQLVLA-NSELTEARTERDQFSQESGN 374
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759145 355 LTQELEELEEQHQQRHKSLkeahvlafqTMEEEKEKEQRALET-------HLQQK---HSAELQSLKDAHRESMEGFRVE 424
Cdd:pfam15921 375 LDDQLQKLLADLHKREKEL---------SLEKEQNKRLWDRDTgnsitidHLRRElddRNMEVQRLEALLKAMKSECQGQ 445
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759145 425 MEQELQTLrfeledEGKAMLASLRSELNHQHATSIDLLRHShHQELAAAKMELERSIDIsrrqskehmcrISDLQDELRH 504
Cdd:pfam15921 446 MERQMAAI------QGKNESLEKVSSLTAQLESTKEMLRKV-VEELTAKKMTLESSERT-----------VSDLTASLQE 507
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759145 505 REHHITDLDKEvqhlhesISTLTKELELKGKEILRIRSESNqqmrlHEQDLNKRLEKeLDVMTADHLREKNIMRADFNKT 584
Cdd:pfam15921 508 KERAIEATNAE-------ITKLRSRVDLKLQELQHLKNEGD-----HLRNVQTECEA-LKLQMAEKDKVIEILRQQIENM 574
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1958759145 585 NELLKE---INAALQVSLEDMEEKylMRESRPEdlqmIAELKSLLTERDQVIKKL---IEDNKFYQLELVN 649
Cdd:pfam15921 575 TQLVGQhgrTAGAMQVEKAQLEKE--INDRRLE----LQEFKILKDKKDAKIRELearVSDLELEKVKLVN 639
|
|
| DUF3584 |
pfam12128 |
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ... |
47-568 |
8.33e-04 |
|
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.
Pssm-ID: 432349 [Multi-domain] Cd Length: 1191 Bit Score: 42.90 E-value: 8.33e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759145 47 MSKKIAQLTKKVNEVkrtqQEYYEMELKNLQTRLEGEVAQLNETHGKTLEELAwKHHMAIEAVHSnasrdkiKLQTELEE 126
Cdd:pfam12128 359 LEERLKALTGKHQDV----TAKYNRRRSKIKEQNNRDIAGIKDKLAKIREARD-RQLAVAEDDLQ-------ALESELRE 426
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759145 127 QHKKEKLSLEEDKNQLQLELENLKQALGDKLTSANQ--EIDRLQDLVRKSEQGLGSAEGliaslqdSQERLQSELDLTKG 204
Cdd:pfam12128 427 QLEAGKLEFNEEEYRLKSRLGELKLRLNQATATPELllQLENFDERIERAREEQEAANA-------EVERLQSELRQARK 499
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759145 205 RLKETKDALLNVEAELQQERHEHEQ---------------------------------------------TLATMKEEE- 238
Cdd:pfam12128 500 RRDQASEALRQASRRLEERQSALDElelqlfpqagtllhflrkeapdweqsigkvispellhrtdldpevWDGSVGGELn 579
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759145 239 ----KLRVDRMAHDLEIKWTENLRQECSKLRQELKLQHEEDKKcAMSQLLQLK------EREKTAARDSWQKKVEDLL-- 306
Cdd:pfam12128 580 lygvKLDLKRIDVPEWAASEEELRERLDKAEEALQSAREKQAA-AEEQLVQANgelekaSREETFARTALKNARLDLRrl 658
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759145 307 -NQRHSLGEALHKSINNISLLKQNLELQLCQSQTSLQQLQAQFTQERQRltqELEELEEQHQQRHKSLKEAHVLAFQTME 385
Cdd:pfam12128 659 fDEKQSEKDKKNKALAERKDSANERLNSLEAQLKQLDKKHQAWLEEQKE---QKREARTEKQAYWQVVEGALDAQLALLK 735
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759145 386 EEKEKEQRALETHLQQKHSAELQSLKDahRESMEGFRVEMEQELQTLRFELEDEGKAMLASLRSELNHQHATSIdllrhs 465
Cdd:pfam12128 736 AAIAARRSGAKAELKALETWYKRDLAS--LGVDPDVIAKLKREIRTLERKIERIAVRRQEVLRYFDWYQETWLQ------ 807
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759145 466 HHQELAAAKMELERSIDISR----RQSKEHMCRISDLQDEL---RHREHHITDLDKEVQHLHESISTL-----TKELELK 533
Cdd:pfam12128 808 RRPRLATQLSNIERAISELQqqlaRLIADTKLRRAKLEMERkasEKQQVRLSENLRGLRCEMSKLATLkedanSEQAQGS 887
|
570 580 590
....*....|....*....|....*....|....*
gi 1958759145 534 GKEILRIRSESNQQMRLHEQDLNKRLEKELDVMTA 568
Cdd:pfam12128 888 IGERLAQLEDLKLKRDYLSESVKKYVEHFKNVIAD 922
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
115-641 |
1.43e-03 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 42.27 E-value: 1.43e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759145 115 RDKIKLQTELEEQHKKEKL----SLEEDKNQLQLELENLKQALGDKLTSANQEIDRLQDLVRKSEQGLGSAEGLIASLQD 190
Cdd:pfam02463 186 AELIIDLEELKLQELKLKEqakkALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEIESSKQEIEKEEE 265
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759145 191 SQERLQSELDLTKGRLKETKDALLNVEAELQQERHEHEQTLATM------KEEEKLRVDRMAHDLEIKWTENLRQECSKL 264
Cdd:pfam02463 266 KLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKvddeekLKESEKEKKKAEKELKKEKEEIEELEKELK 345
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759145 265 RQELKLQHEEDKKCAMSQLLQLKEREKTAARDSWQKKVEDLLNQRHSLGEAL---HKSINNISLLKQNLELQLcQSQTSL 341
Cdd:pfam02463 346 ELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELelkSEEEKEAQLLLELARQLE-DLLKEE 424
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759145 342 QQLQAQFTQERQRLTQELEELEEQHQQRHKSLKEAHVLAFQTMEEEKEKEQRALETHLQQKHSAELQSLKDAHRESMEGF 421
Cdd:pfam02463 425 KKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESK 504
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759145 422 RVEME-------QELQTLRFELEDEGKAMLASLRSELNHQHATSIDLLRHSHHQELAAAKMEL--ERSIDISRRQSKEHM 492
Cdd:pfam02463 505 ARSGLkvllaliKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQKLVraLTELPLGARKLRLLI 584
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759145 493 CRISDLQDELRHREHHIT-------------DLDKEVQHLHESISTLTKELELKGKEILRIRSESNQQMRLHEQDLNKRL 559
Cdd:pfam02463 585 PKLKLPLKSIAVLEIDPIlnlaqldkatleaDEDDKRAKVVEGILKDTELTKLKESAKAKESGLRKGVSLEEGLAEKSEV 664
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759145 560 EKELDVMTaDHLREKNIMRADFNKTNELLKEINAALQVSLEDMEEKYLMRESRPEDLQMIAELKSLLTERDQVIKKLIED 639
Cdd:pfam02463 665 KASLSELT-KELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQ 743
|
..
gi 1958759145 640 NK 641
Cdd:pfam02463 744 KI 745
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
116-636 |
1.88e-03 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 41.59 E-value: 1.88e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759145 116 DKIKLQTELEEQHKKEKLSLEEDKNQLQLELENLKQALgDKLTSANQEIDRLQDLVRKSEQGLGSAEGLIASLQDSQERL 195
Cdd:PRK03918 193 ELIKEKEKELEEVLREINEISSELPELREELEKLEKEV-KELEELKEEIEELEKELESLEGSKRKLEEKIRELEERIEEL 271
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759145 196 QSELDLTKGRLKETKD---------ALLNVEAELQQERHEHEQTLATMKEE----EKLRVDRMAHDLEIKWTENLRQECS 262
Cdd:PRK03918 272 KKEIEELEEKVKELKElkekaeeyiKLSEFYEEYLDELREIEKRLSRLEEEingiEERIKELEEKEERLEELKKKLKELE 351
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759145 263 KLRQELKLQHE--EDKKCAMSQLLQLKEREKTAARDSWQKKVEDLLNQRHSLGEALHKSINNISLLKQNLElQLCQSQTS 340
Cdd:PRK03918 352 KRLEELEERHElyEEAKAKKEELERLKKRLTGLTPEKLEKELEELEKAKEEIEEEISKITARIGELKKEIK-ELKKAIEE 430
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759145 341 LQQLQAQFTQERQRLTQELEELEEQHQQRHKSLKEAHVLAFQTMEEEKEKEQRALETHLqqKHSAELQSLKD------AH 414
Cdd:PRK03918 431 LKKAKGKCPVCGRELTEEHRKELLEEYTAELKRIEKELKEIEEKERKLRKELRELEKVL--KKESELIKLKElaeqlkEL 508
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759145 415 RESMEGFRVE----MEQELQTLRFELeDEGKAMLASLRSELNHQHA-----TSIDLLRHSHHQELAAAKMELERSIDISR 485
Cdd:PRK03918 509 EEKLKKYNLEelekKAEEYEKLKEKL-IKLKGEIKSLKKELEKLEElkkklAELEKKLDELEEELAELLKELEELGFESV 587
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759145 486 RQSKEHMCRISDLQD---ELRHREHHITDLDKEVQHLHESISTLTKELELKGKEILRIRSESNQQMRLHEQDLNKRLEKE 562
Cdd:PRK03918 588 EELEERLKELEPFYNeylELKDAEKELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEELEKKYSEEEYEELREE 667
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1958759145 563 LDVMTADHLRekniMRADFNKTNELLKEINAalqvSLEDMEEKYLMRESRPEDLQMIAELKSLLTERDQVIKKL 636
Cdd:PRK03918 668 YLELSRELAG----LRAELEELEKRREEIKK----TLEKLKEELEEREKAKKELEKLEKALERVEELREKVKKY 733
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
73-249 |
2.64e-03 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 40.29 E-value: 2.64e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759145 73 LKNLQtRLEGEVAQLNETHGKTLEELAwkhhmAIEAVHSNASRDKIKLQTELEEqHKKEKLSLEEDKNQLQLELENLKQA 152
Cdd:COG1579 9 LLDLQ-ELDSELDRLEHRLKELPAELA-----ELEDELAALEARLEAAKTELED-LEKEIKRLELEIEEVEARIKKYEEQ 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759145 153 LGDklTSANQEIDRLQDLVRKSEQGLGSAEGLIASLQDSQERLQSELDLTKGRLKETKDALLNVEAELQQERHEHEQTLA 232
Cdd:COG1579 82 LGN--VRNNKEYEALQKEIESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAELEAELE 159
|
170
....*....|....*..
gi 1958759145 233 TMKEEEKLRVDRMAHDL 249
Cdd:COG1579 160 ELEAEREELAAKIPPEL 176
|
|
| DUF3584 |
pfam12128 |
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ... |
64-561 |
4.92e-03 |
|
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.
Pssm-ID: 432349 [Multi-domain] Cd Length: 1191 Bit Score: 40.59 E-value: 4.92e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759145 64 TQQEYYEMELKNLQTRLEGEVAQLNETHGKTLEELawkhhmaieavhSNASRDKIKLQTELEEQHKKEKLSLEEDKNQLQ 143
Cdd:pfam12128 276 SRQEERQETSAELNQLLRTLDDQWKEKRDELNGEL------------SAADAAVAKDRSELEALEDQHGAFLDADIETAA 343
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759145 144 LELENLKQALGDkLTSANQEIDRLQDLVRKSEQGLGSAEGLIAS-LQDSQERLQSELDltkgRLKETKDALLNV-EAELQ 221
Cdd:pfam12128 344 ADQEQLPSWQSE-LENLEERLKALTGKHQDVTAKYNRRRSKIKEqNNRDIAGIKDKLA----KIREARDRQLAVaEDDLQ 418
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759145 222 QE----RHEHEQTLATMKEEEKLRVDRMAHdleikwtENLRQECSKLRQELKLQ-----------HEEDKKCAMSQL-LQ 285
Cdd:pfam12128 419 ALeselREQLEAGKLEFNEEEYRLKSRLGE-------LKLRLNQATATPELLLQlenfderieraREEQEAANAEVErLQ 491
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759145 286 LKEREKTAARDSWQKKVEDL---LNQRHSLGEALH--------------------------KSINNISLLKQNLELQLCQ 336
Cdd:pfam12128 492 SELRQARKRRDQASEALRQAsrrLEERQSALDELElqlfpqagtllhflrkeapdweqsigKVISPELLHRTDLDPEVWD 571
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759145 337 SQTSLQQ---------------LQAQFTQERQRLTQELEELEEQHQQRHKSLKEAHVLAFQTMEEEKEKEQRALETHLQ- 400
Cdd:pfam12128 572 GSVGGELnlygvkldlkridvpEWAASEEELRERLDKAEEALQSAREKQAAAEEQLVQANGELEKASREETFARTALKNa 651
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759145 401 ----QKHSAELQSLKDAHRESMEGFRVEMEQELQTLRFE---LEDEGKAMLASLRSELNhQHATSIDLLRHSHHQELAAA 473
Cdd:pfam12128 652 rldlRRLFDEKQSEKDKKNKALAERKDSANERLNSLEAQlkqLDKKHQAWLEEQKEQKR-EARTEKQAYWQVVEGALDAQ 730
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759145 474 KMELERSIDISRRQSKEHMCRI-SDLQDELRHR---EHHITDLDKEVQHLHESIStltkELELKGKEILRIRSESNQQMR 549
Cdd:pfam12128 731 LALLKAAIAARRSGAKAELKALeTWYKRDLASLgvdPDVIAKLKREIRTLERKIE----RIAVRRQEVLRYFDWYQETWL 806
|
570
....*....|..
gi 1958759145 550 LHEQDLNKRLEK 561
Cdd:pfam12128 807 QRRPRLATQLSN 818
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
468-647 |
5.89e-03 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 39.75 E-value: 5.89e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759145 468 QELAAAKMELERSIDISRRQSKEHMCRISDLQDELRHREHHITDLDKEVQHLHESISTLTKELELKGKEILRIRSESNQQ 547
Cdd:COG4942 23 AEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQ 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759145 548 M-----RLHEQDLNKRLEKELDVMTADHLREKNIMRADFNKTNELLKEINAALQVSLEDMEEKYLMRESRPEDLQMI--- 619
Cdd:COG4942 103 KeelaeLLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALlae 182
|
170 180 190
....*....|....*....|....*....|...
gi 1958759145 620 -----AELKSLLTERDQVIKKLIEDNKFYQLEL 647
Cdd:COG4942 183 leeerAALEALKAERQKLLARLEKELAELAAEL 215
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
119-531 |
6.23e-03 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 40.14 E-value: 6.23e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759145 119 KLQTELEEQHKKEKLSLEEDKNQLQlELENLKQALGDKLTSANQEIDRLQDLvrksEQGLGSAEGLIASLQDSQERLQSE 198
Cdd:COG4717 50 RLEKEADELFKPQGRKPELNLKELK-ELEEELKEAEEKEEEYAELQEELEEL----EEELEELEAELEELREELEKLEKL 124
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759145 199 LDL--TKGRLKETKDALLNVEAELQQERHEHEQTLATMKEEEKLRVDRmahdleikwtENLRQECSKLRQELKLQHEEDK 276
Cdd:COG4717 125 LQLlpLYQELEALEAELAELPERLEELEERLEELRELEEELEELEAEL----------AELQEELEELLEQLSLATEEEL 194
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759145 277 KCAMSQLLQLKEREKTA--ARDSWQKKVEDLLNQRHSLGEALHKSINNISLLKQNLELQLCQSQTSLQQLQAQFTQERQR 354
Cdd:COG4717 195 QDLAEELEELQQRLAELeeELEEAQEELEELEEELEQLENELEAAALEERLKEARLLLLIAAALLALLGLGGSLLSLILT 274
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759145 355 LTQELEELE-EQHQQRHKSLKEAHVLAFQTMEEEKEKEQRALETHLQQKHSAELQSLKDAHRESMEGFrVEMEQELQTLR 433
Cdd:COG4717 275 IAGVLFLVLgLLALLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLEL-LDRIEELQELL 353
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759145 434 FELEDEGKAM-----LASLRSELNHQHATSIDLLR-----HSHHQELAAAKMELERSIDISRRQSKEHMCRIS--DLQDE 501
Cdd:COG4717 354 REAEELEEELqleelEQEIAALLAEAGVEDEEELRaaleqAEEYQELKEELEELEEQLEELLGELEELLEALDeeELEEE 433
|
410 420 430
....*....|....*....|....*....|
gi 1958759145 502 LRHREHHITDLDKEVQHLHESISTLTKELE 531
Cdd:COG4717 434 LEELEEELEELEEELEELREELAELEAELE 463
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
127-553 |
6.74e-03 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 39.95 E-value: 6.74e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759145 127 QHKKEKLSLEEDKNQLQLELENLKQALGDKLtsanQEIDRLQDLVRKSEQGLGSAEGLIASLQDSQERLQSELDltkgRL 206
Cdd:TIGR00618 466 QSLKEREQQLQTKEQIHLQETRKKAVVLARL----LELQEEPCPLCGSCIHPNPARQDIDNPGPLTRRMQRGEQ----TY 537
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759145 207 KETKDALLNVEAELQQERhEHEQTLatmkEEEKLRVDRMAHDLEIKWT------ENLRQECSKLRQELKLQHEEDKKCAM 280
Cdd:TIGR00618 538 AQLETSEEDVYHQLTSER-KQRASL----KEQMQEIQQSFSILTQCDNrskediPNLQNITVRLQDLTEKLSEAEDMLAC 612
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759145 281 sqLLQLKEREKTAARDSWQKKVEDLLNQRHSLGEALHKSINNISLLKQNLELQLcqsqTSLQQLQAQFTQERQRLTQELE 360
Cdd:TIGR00618 613 --EQHALLRKLQPEQDLQDVRLHLQQCSQELALKLTALHALQLTLTQERVREHA----LSIRVLPKELLASRQLALQKMQ 686
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759145 361 ELEEQHQQRHKSLkeAHVLAFQTMEEEKEKEQRALETHLQQKHSA---ELQSLKDAHRESMEGFRVEMEQELQTLRFELE 437
Cdd:TIGR00618 687 SEKEQLTYWKEML--AQCQTLLRELETHIEEYDREFNEIENASSSlgsDLAAREDALNQSLKELMHQARTVLKARTEAHF 764
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759145 438 DEGKAMLASLRSELNHQHATSIDLLRHSHHQELAAAKMELERSIdisrRQSKEHMCRISDLQDELRHREHHitDLDKEVQ 517
Cdd:TIGR00618 765 NNNEEVTAALQTGAELSHLAAEIQFFNRLREEDTHLLKTLEAEI----GQEIPSDEDILNLQCETLVQEEE--QFLSRLE 838
|
410 420 430
....*....|....*....|....*....|....*.
gi 1958759145 518 HLHESISTLTKELELKGKEILRIRSESNQQMRLHEQ 553
Cdd:TIGR00618 839 EKSATLGEITHQLLKYEECSKQLAQLTQEQAKIIQL 874
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
48-297 |
8.35e-03 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 39.67 E-value: 8.35e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759145 48 SKKIAQLTKKVNEVKRtQQEYYEMELKNLQTRLEGEVAQLNETHGKTLEELAWKHHmaIEAVHSNASRDKIKLQTELEEq 127
Cdd:TIGR02169 708 SQELSDASRKIGEIEK-EIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKE--LEARIEELEEDLHKLEEALND- 783
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759145 128 hkkeklsLEEDKNQLQLelenlkQALGDKLTSANQEIDRLQDLVRKSEQGLGSAEGLIASLQDSQERLQSELDLTKGRLK 207
Cdd:TIGR02169 784 -------LEARLSHSRI------PEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIK 850
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759145 208 ETKDALLNVEA---ELQQERHEHEQTLATMKEE-EKLRVDRMAHDLEIKWTENLRQECSKLRQELKLQHEEDKKCAMSQL 283
Cdd:TIGR02169 851 SIEKEIENLNGkkeELEEELEELEAALRDLESRlGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALE 930
|
250
....*....|....
gi 1958759145 284 LQLKEREKTAARDS 297
Cdd:TIGR02169 931 EELSEIEDPKGEDE 944
|
|
| SCP-1 |
pfam05483 |
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ... |
119-564 |
9.27e-03 |
|
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.
Pssm-ID: 114219 [Multi-domain] Cd Length: 787 Bit Score: 39.32 E-value: 9.27e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759145 119 KLQTELEEQHKKEKLSLEEDKNQLQLELENLKQALGDKltsaNQEIDRLQDLVRKSEQGLGSAEGLIASLQDSQERLQSE 198
Cdd:pfam05483 201 ELRVQAENARLEMHFKLKEDHEKIQHLEEEYKKEINDK----EKQVSLLLIQITEKENKMKDLTFLLEESRDKANQLEEK 276
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759145 199 LDLTKGRLKETKDALLNVEAELQQERHEHEQTLATMK---EEEKLRVDRMAHDLEIKWTENLRQECSKLRQELKLQHEED 275
Cdd:pfam05483 277 TKLQDENLKELIEKKDHLTKELEDIKMSLQRSMSTQKaleEDLQIATKTICQLTEEKEAQMEELNKAKAAHSFVVTEFEA 356
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759145 276 KKCAMSQLLQlKEREKTAARDSWQKKVEDLLNQRHSLGEALHKSINNISLLKQNLElQLCQSQTSLQQLQAQFTQERQRL 355
Cdd:pfam05483 357 TTCSLEELLR-TEQQRLEKNEDQLKIITMELQKKSSELEEMTKFKNNKEVELEELK-KILAEDEKLLDEKKQFEKIAEEL 434
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759145 356 TQELEELEEQHQQRHKSLK--EAHVLAFQTMEEEKEKEQRALETHLQQKHSAELQSLKDAHRESMEGfrVEMEQELQTLR 433
Cdd:pfam05483 435 KGKEQELIFLLQAREKEIHdlEIQLTAIKTSEEHYLKEVEDLKTELEKEKLKNIELTAHCDKLLLEN--KELTQEASDMT 512
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759145 434 FELEDEGKAMLASLRSElnHQHATSIDLLRHSHHQelaaAKMELERSIDISRRQSKEHMCRISDLQDELRHREHHITDLD 513
Cdd:pfam05483 513 LELKKHQEDIINCKKQE--ERMLKQIENLEEKEMN----LRDELESVREEFIQKGDEVKCKLDKSEENARSIEYEVLKKE 586
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1958759145 514 KEVQHLHESISTLTKELELKGKEILRIRSES----------NQQMRLHEQDLNKrLEKELD 564
Cdd:pfam05483 587 KQMKILENKCNNLKKQIENKNKNIEELHQENkalkkkgsaeNKQLNAYEIKVNK-LELELA 646
|
|
| |
