|
Name |
Accession |
Description |
Interval |
E-value |
| FN3 |
COG3401 |
Fibronectin type 3 domain [General function prediction only]; |
936-1168 |
6.11e-20 |
|
Fibronectin type 3 domain [General function prediction only];
:
Pssm-ID: 442628 [Multi-domain] Cd Length: 603 Bit Score: 95.84 E-value: 6.11e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958807392 936 YEVKGLIPATTYFCRVQAVNIVGVGMFGGTAKVTTPGTVPAMVPMLQEVEnkvpakQSSTCIAIRWEEPDCHGsqITGYN 1015
Cdd:COG3401 194 DGGGDIEPGTTYYYRVAATDTGGESAPSNEVSVTTPTTPPSAPTGLTATA------DTPGSVTLSWDPVTESD--ATGYR 265
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958807392 1016 IEYGD------KKIVTVKrVTEYVLKNLQPNTTYRIRIQAINHYGL-SPFSPSIRCKTKPLPPEPPQ-LNCVVYGHQSLR 1087
Cdd:COG3401 266 VYRSNsgdgpfTKVATVT-TTSYTDTGLTNGTTYYYRVTAVDAAGNeSAPSNVVSVTTDLTPPAAPSgLTATAVGSSSIT 344
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958807392 1088 LKWGTVSSkkslANFISYNLL-MEDRSGRFSVIYRG-TDVTHKVQKLTEYTQYKFKIQACNEAG-EGPESDIYTFTTTKS 1164
Cdd:COG3401 345 LSWTASSD----ADVTGYNVYrSTSGGGTYTKIAETvTTTSYTDTGLTPGTTYYYKVTAVDAAGnESAPSEEVSATTASA 420
|
....
gi 1958807392 1165 PPTA 1168
Cdd:COG3401 421 ASGE 424
|
|
| FN3 super family |
cl27307 |
Fibronectin type 3 domain [General function prediction only]; |
617-847 |
1.61e-15 |
|
Fibronectin type 3 domain [General function prediction only];
The actual alignment was detected with superfamily member COG3401:
Pssm-ID: 442628 [Multi-domain] Cd Length: 603 Bit Score: 81.59 E-value: 1.61e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958807392 617 LSPSTKYSFRLAAKNHFGCSNFSETAVFYTSGNTPSAPLPPKLKEAGVYSLSLEWcaptNPNPNDTLT-YVLEMEEAKSG 695
Cdd:COG3401 199 IEPGTTYYYRVAATDTGGESAPSNEVSVTTPTTPPSAPTGLTATADTPGSVTLSW----DPVTESDATgYRVYRSNSGDG 274
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958807392 696 lGFKPKYNGEDLSCTVKNLQRNTTYKFRIFAYNLEG-RSNPSGEVKYTTRPARPGCPnkPHVVGTIHA-RQVTIGWDLPK 773
Cdd:COG3401 275 -PFTKVATVTTTSYTDTGLTNGTTYYYRVTAVDAAGnESAPSNVVSVTTDLTPPAAP--SGLTATAVGsSSITLSWTASS 351
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1958807392 774 DNggmNISSYSLEVCENSDaGNLWKIIYSGTLQEFLYDDLQPGTTYKLRVFCTSPAG-QSRPSDVLTIQTPALPP 847
Cdd:COG3401 352 DA---DVTGYNVYRSTSGG-GTYTKIAETVTTTSYTDTGLTPGTTYYYKVTAVDAAGnESAPSEEVSATTASAAS 422
|
|
| FN3 |
cd00063 |
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ... |
556-646 |
4.94e-14 |
|
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.
:
Pssm-ID: 238020 [Multi-domain] Cd Length: 93 Bit Score: 69.06 E-value: 4.94e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958807392 556 PDPPLAPTLISRTKNSLNLQWKGCNDNGSKISSFLLEWDEGIGEDFKSCYTGPLKQ--HKLFKLSPSTKYSFRLAAKNHF 633
Cdd:cd00063 1 PSPPTNLRVTDVTSTSVTLSWTPPEDDGGPITGYVVEYREKGSGDWKEVEVTPGSEtsYTLTGLKPGTEYEFRVRAVNGG 80
|
90
....*....|...
gi 1958807392 634 GCSNFSETAVFYT 646
Cdd:cd00063 81 GESPPSESVTVTT 93
|
|
| fn3 |
pfam00041 |
Fibronectin type III domain; |
904-962 |
2.09e-05 |
|
Fibronectin type III domain;
:
Pssm-ID: 394996 [Multi-domain] Cd Length: 85 Bit Score: 44.33 E-value: 2.09e-05
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1958807392 904 PKCNGAEIIDYRLQWGQV---EESMHLIYTGPCLRYEVKGLIPATTYFCRVQAVNIVGVGMF 962
Cdd:pfam00041 23 PPDGNGPITGYEVEYRPKnsgEPWNEITVPGTTTSVTLTGLKPGTEYEVRVQAVNGGGEGPP 84
|
|
| Pur_ac_phosph_N |
pfam16656 |
Purple acid Phosphatase, N-terminal domain; This domain is found at the N-terminus of Purple ... |
470-551 |
2.78e-04 |
|
Purple acid Phosphatase, N-terminal domain; This domain is found at the N-terminus of Purple acid phosphatase proteins.
:
Pssm-ID: 465220 [Multi-domain] Cd Length: 93 Bit Score: 41.24 E-value: 2.78e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958807392 470 TRSATVSWALNSAEK-----YDINSpmkFELTLSSSGKNGNYKNIYTGDGV--TVVLHDLQPCTVYFLRVaiiRDGEHRn 542
Cdd:pfam16656 12 STSMTVSWVTPSAVTspvvqYGTSS---SALTSTATATSSTYTTGDGGTGYihRATLTGLEPGTTYYYRV---GDDNGG- 84
|
....*....
gi 1958807392 543 VSEVVSFTT 551
Cdd:pfam16656 85 WSEVYSFTT 93
|
|
| ROM1 super family |
cl34999 |
RhoGEF, Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases [Signal transduction ... |
229-520 |
5.57e-03 |
|
RhoGEF, Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases [Signal transduction mechanisms];
The actual alignment was detected with superfamily member COG5422:
Pssm-ID: 227709 [Multi-domain] Cd Length: 1175 Bit Score: 41.42 E-value: 5.57e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958807392 229 SKKKIRDRQLGeHKISSTFSDTPLLlnkvidisaPSGTLCPYTVDTAPSTNTDTSPLDTYSLNTVlkacttdsTPRNMAD 308
Cdd:COG5422 59 SKESFGKYALG-HQIFSSFSSSPKL---------FQRRNSAGPITHSPSATSSTSSLNSNDGDQF--------SPASDSL 120
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958807392 309 NIPDTNTTDR---NTSSGhSPSNSTSNAFCSDNSNDITSPSINTYDlvTSDETHEPPDAKSIPSYTSEStcnalitenAQ 385
Cdd:COG5422 121 SFNPSSTQSRkdsGPGDG-SPVQKRKNPLLPSSSTHGTHPPIVFTD--NNGSHAGAPNARSRKEIPSLG---------SQ 188
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958807392 386 TCSSNKDDLRPSGAATISNNTRAYTEDNPGETETNMGAGDSKQISDENQRKRHSSNASvrEHNTEYGTQPCCSNIEkpvV 465
Cdd:COG5422 189 SMQLPSPHFRQKFSSSDTSNGFSYPSIRKNSRHSSNSMPSFPHSSTAVLLKRHSGSSG--ASLISSNITPSSSNSE---A 263
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*..
gi 1958807392 466 SNIQTRSATVSWALNSAekydINSPMKFELTLSSSGKNGN-YKNIYTGD-GVTVVLH 520
Cdd:COG5422 264 MSTSSKRPYIYPALLSR----VAVEFKMRLQLGDHKKDGLlYRDAFTGSeAVDVLML 316
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| FN3 |
COG3401 |
Fibronectin type 3 domain [General function prediction only]; |
936-1168 |
6.11e-20 |
|
Fibronectin type 3 domain [General function prediction only];
Pssm-ID: 442628 [Multi-domain] Cd Length: 603 Bit Score: 95.84 E-value: 6.11e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958807392 936 YEVKGLIPATTYFCRVQAVNIVGVGMFGGTAKVTTPGTVPAMVPMLQEVEnkvpakQSSTCIAIRWEEPDCHGsqITGYN 1015
Cdd:COG3401 194 DGGGDIEPGTTYYYRVAATDTGGESAPSNEVSVTTPTTPPSAPTGLTATA------DTPGSVTLSWDPVTESD--ATGYR 265
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958807392 1016 IEYGD------KKIVTVKrVTEYVLKNLQPNTTYRIRIQAINHYGL-SPFSPSIRCKTKPLPPEPPQ-LNCVVYGHQSLR 1087
Cdd:COG3401 266 VYRSNsgdgpfTKVATVT-TTSYTDTGLTNGTTYYYRVTAVDAAGNeSAPSNVVSVTTDLTPPAAPSgLTATAVGSSSIT 344
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958807392 1088 LKWGTVSSkkslANFISYNLL-MEDRSGRFSVIYRG-TDVTHKVQKLTEYTQYKFKIQACNEAG-EGPESDIYTFTTTKS 1164
Cdd:COG3401 345 LSWTASSD----ADVTGYNVYrSTSGGGTYTKIAETvTTTSYTDTGLTPGTTYYYKVTAVDAAGnESAPSEEVSATTASA 420
|
....
gi 1958807392 1165 PPTA 1168
Cdd:COG3401 421 ASGE 424
|
|
| FN3 |
cd00063 |
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ... |
993-1066 |
1.46e-16 |
|
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.
Pssm-ID: 238020 [Multi-domain] Cd Length: 93 Bit Score: 76.00 E-value: 1.46e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958807392 993 SSTCIAIRWEEPDCHGSQITGYNIEYGDKKIVTVKRV-------TEYVLKNLQPNTTYRIRIQAINHYGLSPFSPSIRCK 1065
Cdd:cd00063 13 TSTSVTLSWTPPEDDGGPITGYVVEYREKGSGDWKEVevtpgseTSYTLTGLKPGTEYEFRVRAVNGGGESPPSESVTVT 92
|
.
gi 1958807392 1066 T 1066
Cdd:cd00063 93 T 93
|
|
| FN3 |
COG3401 |
Fibronectin type 3 domain [General function prediction only]; |
617-847 |
1.61e-15 |
|
Fibronectin type 3 domain [General function prediction only];
Pssm-ID: 442628 [Multi-domain] Cd Length: 603 Bit Score: 81.59 E-value: 1.61e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958807392 617 LSPSTKYSFRLAAKNHFGCSNFSETAVFYTSGNTPSAPLPPKLKEAGVYSLSLEWcaptNPNPNDTLT-YVLEMEEAKSG 695
Cdd:COG3401 199 IEPGTTYYYRVAATDTGGESAPSNEVSVTTPTTPPSAPTGLTATADTPGSVTLSW----DPVTESDATgYRVYRSNSGDG 274
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958807392 696 lGFKPKYNGEDLSCTVKNLQRNTTYKFRIFAYNLEG-RSNPSGEVKYTTRPARPGCPnkPHVVGTIHA-RQVTIGWDLPK 773
Cdd:COG3401 275 -PFTKVATVTTTSYTDTGLTNGTTYYYRVTAVDAAGnESAPSNVVSVTTDLTPPAAP--SGLTATAVGsSSITLSWTASS 351
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1958807392 774 DNggmNISSYSLEVCENSDaGNLWKIIYSGTLQEFLYDDLQPGTTYKLRVFCTSPAG-QSRPSDVLTIQTPALPP 847
Cdd:COG3401 352 DA---DVTGYNVYRSTSGG-GTYTKIAETVTTTSYTDTGLTPGTTYYYKVTAVDAAGnESAPSEEVSATTASAAS 422
|
|
| FN3 |
cd00063 |
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ... |
556-646 |
4.94e-14 |
|
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.
Pssm-ID: 238020 [Multi-domain] Cd Length: 93 Bit Score: 69.06 E-value: 4.94e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958807392 556 PDPPLAPTLISRTKNSLNLQWKGCNDNGSKISSFLLEWDEGIGEDFKSCYTGPLKQ--HKLFKLSPSTKYSFRLAAKNHF 633
Cdd:cd00063 1 PSPPTNLRVTDVTSTSVTLSWTPPEDDGGPITGYVVEYREKGSGDWKEVEVTPGSEtsYTLTGLKPGTEYEFRVRAVNGG 80
|
90
....*....|...
gi 1958807392 634 GCSNFSETAVFYT 646
Cdd:cd00063 81 GESPPSESVTVTT 93
|
|
| FN3 |
cd00063 |
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ... |
651-743 |
4.16e-12 |
|
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.
Pssm-ID: 238020 [Multi-domain] Cd Length: 93 Bit Score: 63.28 E-value: 4.16e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958807392 651 PSAPLPPKLKEAGVYSLSLEWCAPTNPNPNDTlTYVLEMEEAKSGLGFK-PKYNGEDLSCTVKNLQRNTTYKFRIFAYNL 729
Cdd:cd00063 1 PSPPTNLRVTDVTSTSVTLSWTPPEDDGGPIT-GYVVEYREKGSGDWKEvEVTPGSETSYTLTGLKPGTEYEFRVRAVNG 79
|
90
....*....|....
gi 1958807392 730 EGRSNPSGEVKYTT 743
Cdd:cd00063 80 GGESPPSESVTVTT 93
|
|
| fn3 |
pfam00041 |
Fibronectin type III domain; |
992-1059 |
7.69e-12 |
|
Fibronectin type III domain;
Pssm-ID: 394996 [Multi-domain] Cd Length: 85 Bit Score: 62.43 E-value: 7.69e-12
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1958807392 992 QSSTCIAIRWEEPDCHGSQITGYNIEY------GDKKIVTVKRVT-EYVLKNLQPNTTYRIRIQAINHYGLSPFS 1059
Cdd:pfam00041 11 VTSTSLTVSWTPPPDGNGPITGYEVEYrpknsgEPWNEITVPGTTtSVTLTGLKPGTEYEVRVQAVNGGGEGPPS 85
|
|
| FN3 |
smart00060 |
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ... |
993-1056 |
3.11e-11 |
|
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.
Pssm-ID: 214495 [Multi-domain] Cd Length: 83 Bit Score: 60.71 E-value: 3.11e-11
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1958807392 993 SSTCIAIRWEEP--DCHGSQITGYNIEYGD-----KKIVTVKRVTEYVLKNLQPNTTYRIRIQAINHYGLS 1056
Cdd:smart00060 13 TSTSVTLSWEPPpdDGITGYIVGYRVEYREegsewKEVNVTPSSTSYTLTGLKPGTEYEFRVRAVNGAGEG 83
|
|
| FN3 |
smart00060 |
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ... |
651-733 |
8.87e-09 |
|
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.
Pssm-ID: 214495 [Multi-domain] Cd Length: 83 Bit Score: 53.77 E-value: 8.87e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958807392 651 PSAPLPPKLKEAGVYSLSLEWCAPTNPNPNDTLTYVLEMEEAKSGLGFKPKYNGEDLSCTVKNLQRNTTYKFRIFAYNLE 730
Cdd:smart00060 1 PSPPSNLRVTDVTSTSVTLSWEPPPDDGITGYIVGYRVEYREEGSEWKEVNVTPSSTSYTLTGLKPGTEYEFRVRAVNGA 80
|
...
gi 1958807392 731 GRS 733
Cdd:smart00060 81 GEG 83
|
|
| FN3 |
smart00060 |
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ... |
556-636 |
5.35e-08 |
|
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.
Pssm-ID: 214495 [Multi-domain] Cd Length: 83 Bit Score: 51.46 E-value: 5.35e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958807392 556 PDPPLAPTLISRTKNSLNLQWKGCNDNG--SKISSFLLEWDEGIGEDFKSCYTGPLKQHKLFKLSPSTKYSFRLAAKNHF 633
Cdd:smart00060 1 PSPPSNLRVTDVTSTSVTLSWEPPPDDGitGYIVGYRVEYREEGSEWKEVNVTPSSTSYTLTGLKPGTEYEFRVRAVNGA 80
|
...
gi 1958807392 634 GCS 636
Cdd:smart00060 81 GEG 83
|
|
| fn3 |
pfam00041 |
Fibronectin type III domain; |
557-639 |
2.86e-07 |
|
Fibronectin type III domain;
Pssm-ID: 394996 [Multi-domain] Cd Length: 85 Bit Score: 49.34 E-value: 2.86e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958807392 557 DPPLAPTLISRTKNSLNLQWKGCNDNGSKISSFLLEWDEGIGEDFKSCYT--GPLKQHKLFKLSPSTKYSFRLAAKNHFG 634
Cdd:pfam00041 1 SAPSNLTVTDVTSTSLTVSWTPPPDGNGPITGYEVEYRPKNSGEPWNEITvpGTTTSVTLTGLKPGTEYEVRVQAVNGGG 80
|
....*
gi 1958807392 635 CSNFS 639
Cdd:pfam00041 81 EGPPS 85
|
|
| fn3 |
pfam00041 |
Fibronectin type III domain; |
652-736 |
1.31e-05 |
|
Fibronectin type III domain;
Pssm-ID: 394996 [Multi-domain] Cd Length: 85 Bit Score: 44.71 E-value: 1.31e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958807392 652 SAPLPPKLKEAGVYSLSLEWCAPTNPNPNDTlTYVLEMEEAKSGLGFKPKYNGEDL-SCTVKNLQRNTTYKFRIFAYNLE 730
Cdd:pfam00041 1 SAPSNLTVTDVTSTSLTVSWTPPPDGNGPIT-GYEVEYRPKNSGEPWNEITVPGTTtSVTLTGLKPGTEYEVRVQAVNGG 79
|
....*.
gi 1958807392 731 GRSNPS 736
Cdd:pfam00041 80 GEGPPS 85
|
|
| fn3 |
pfam00041 |
Fibronectin type III domain; |
904-962 |
2.09e-05 |
|
Fibronectin type III domain;
Pssm-ID: 394996 [Multi-domain] Cd Length: 85 Bit Score: 44.33 E-value: 2.09e-05
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1958807392 904 PKCNGAEIIDYRLQWGQV---EESMHLIYTGPCLRYEVKGLIPATTYFCRVQAVNIVGVGMF 962
Cdd:pfam00041 23 PPDGNGPITGYEVEYRPKnsgEPWNEITVPGTTTSVTLTGLKPGTEYEVRVQAVNGGGEGPP 84
|
|
| Pur_ac_phosph_N |
pfam16656 |
Purple acid Phosphatase, N-terminal domain; This domain is found at the N-terminus of Purple ... |
470-551 |
2.78e-04 |
|
Purple acid Phosphatase, N-terminal domain; This domain is found at the N-terminus of Purple acid phosphatase proteins.
Pssm-ID: 465220 [Multi-domain] Cd Length: 93 Bit Score: 41.24 E-value: 2.78e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958807392 470 TRSATVSWALNSAEK-----YDINSpmkFELTLSSSGKNGNYKNIYTGDGV--TVVLHDLQPCTVYFLRVaiiRDGEHRn 542
Cdd:pfam16656 12 STSMTVSWVTPSAVTspvvqYGTSS---SALTSTATATSSTYTTGDGGTGYihRATLTGLEPGTTYYYRV---GDDNGG- 84
|
....*....
gi 1958807392 543 VSEVVSFTT 551
Cdd:pfam16656 85 WSEVYSFTT 93
|
|
| FN3 |
smart00060 |
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ... |
907-960 |
5.60e-04 |
|
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.
Pssm-ID: 214495 [Multi-domain] Cd Length: 83 Bit Score: 39.91 E-value: 5.60e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*
gi 1958807392 907 NGAEIIDYRLQWGQVEES-MHLIYTGPCLRYEVKGLIPATTYFCRVQAVNIVGVG 960
Cdd:smart00060 29 ITGYIVGYRVEYREEGSEwKEVNVTPSSTSYTLTGLKPGTEYEFRVRAVNGAGEG 83
|
|
| ROM1 |
COG5422 |
RhoGEF, Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases [Signal transduction ... |
229-520 |
5.57e-03 |
|
RhoGEF, Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases [Signal transduction mechanisms];
Pssm-ID: 227709 [Multi-domain] Cd Length: 1175 Bit Score: 41.42 E-value: 5.57e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958807392 229 SKKKIRDRQLGeHKISSTFSDTPLLlnkvidisaPSGTLCPYTVDTAPSTNTDTSPLDTYSLNTVlkacttdsTPRNMAD 308
Cdd:COG5422 59 SKESFGKYALG-HQIFSSFSSSPKL---------FQRRNSAGPITHSPSATSSTSSLNSNDGDQF--------SPASDSL 120
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958807392 309 NIPDTNTTDR---NTSSGhSPSNSTSNAFCSDNSNDITSPSINTYDlvTSDETHEPPDAKSIPSYTSEStcnalitenAQ 385
Cdd:COG5422 121 SFNPSSTQSRkdsGPGDG-SPVQKRKNPLLPSSSTHGTHPPIVFTD--NNGSHAGAPNARSRKEIPSLG---------SQ 188
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958807392 386 TCSSNKDDLRPSGAATISNNTRAYTEDNPGETETNMGAGDSKQISDENQRKRHSSNASvrEHNTEYGTQPCCSNIEkpvV 465
Cdd:COG5422 189 SMQLPSPHFRQKFSSSDTSNGFSYPSIRKNSRHSSNSMPSFPHSSTAVLLKRHSGSSG--ASLISSNITPSSSNSE---A 263
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*..
gi 1958807392 466 SNIQTRSATVSWALNSAekydINSPMKFELTLSSSGKNGN-YKNIYTGD-GVTVVLH 520
Cdd:COG5422 264 MSTSSKRPYIYPALLSR----VAVEFKMRLQLGDHKKDGLlYRDAFTGSeAVDVLML 316
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| FN3 |
COG3401 |
Fibronectin type 3 domain [General function prediction only]; |
936-1168 |
6.11e-20 |
|
Fibronectin type 3 domain [General function prediction only];
Pssm-ID: 442628 [Multi-domain] Cd Length: 603 Bit Score: 95.84 E-value: 6.11e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958807392 936 YEVKGLIPATTYFCRVQAVNIVGVGMFGGTAKVTTPGTVPAMVPMLQEVEnkvpakQSSTCIAIRWEEPDCHGsqITGYN 1015
Cdd:COG3401 194 DGGGDIEPGTTYYYRVAATDTGGESAPSNEVSVTTPTTPPSAPTGLTATA------DTPGSVTLSWDPVTESD--ATGYR 265
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958807392 1016 IEYGD------KKIVTVKrVTEYVLKNLQPNTTYRIRIQAINHYGL-SPFSPSIRCKTKPLPPEPPQ-LNCVVYGHQSLR 1087
Cdd:COG3401 266 VYRSNsgdgpfTKVATVT-TTSYTDTGLTNGTTYYYRVTAVDAAGNeSAPSNVVSVTTDLTPPAAPSgLTATAVGSSSIT 344
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958807392 1088 LKWGTVSSkkslANFISYNLL-MEDRSGRFSVIYRG-TDVTHKVQKLTEYTQYKFKIQACNEAG-EGPESDIYTFTTTKS 1164
Cdd:COG3401 345 LSWTASSD----ADVTGYNVYrSTSGGGTYTKIAETvTTTSYTDTGLTPGTTYYYKVTAVDAAGnESAPSEEVSATTASA 420
|
....
gi 1958807392 1165 PPTA 1168
Cdd:COG3401 421 ASGE 424
|
|
| FN3 |
cd00063 |
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ... |
993-1066 |
1.46e-16 |
|
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.
Pssm-ID: 238020 [Multi-domain] Cd Length: 93 Bit Score: 76.00 E-value: 1.46e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958807392 993 SSTCIAIRWEEPDCHGSQITGYNIEYGDKKIVTVKRV-------TEYVLKNLQPNTTYRIRIQAINHYGLSPFSPSIRCK 1065
Cdd:cd00063 13 TSTSVTLSWTPPEDDGGPITGYVVEYREKGSGDWKEVevtpgseTSYTLTGLKPGTEYEFRVRAVNGGGESPPSESVTVT 92
|
.
gi 1958807392 1066 T 1066
Cdd:cd00063 93 T 93
|
|
| FN3 |
COG3401 |
Fibronectin type 3 domain [General function prediction only]; |
617-847 |
1.61e-15 |
|
Fibronectin type 3 domain [General function prediction only];
Pssm-ID: 442628 [Multi-domain] Cd Length: 603 Bit Score: 81.59 E-value: 1.61e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958807392 617 LSPSTKYSFRLAAKNHFGCSNFSETAVFYTSGNTPSAPLPPKLKEAGVYSLSLEWcaptNPNPNDTLT-YVLEMEEAKSG 695
Cdd:COG3401 199 IEPGTTYYYRVAATDTGGESAPSNEVSVTTPTTPPSAPTGLTATADTPGSVTLSW----DPVTESDATgYRVYRSNSGDG 274
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958807392 696 lGFKPKYNGEDLSCTVKNLQRNTTYKFRIFAYNLEG-RSNPSGEVKYTTRPARPGCPnkPHVVGTIHA-RQVTIGWDLPK 773
Cdd:COG3401 275 -PFTKVATVTTTSYTDTGLTNGTTYYYRVTAVDAAGnESAPSNVVSVTTDLTPPAAP--SGLTATAVGsSSITLSWTASS 351
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1958807392 774 DNggmNISSYSLEVCENSDaGNLWKIIYSGTLQEFLYDDLQPGTTYKLRVFCTSPAG-QSRPSDVLTIQTPALPP 847
Cdd:COG3401 352 DA---DVTGYNVYRSTSGG-GTYTKIAETVTTTSYTDTGLTPGTTYYYKVTAVDAAGnESAPSEEVSATTASAAS 422
|
|
| FN3 |
cd00063 |
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ... |
556-646 |
4.94e-14 |
|
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.
Pssm-ID: 238020 [Multi-domain] Cd Length: 93 Bit Score: 69.06 E-value: 4.94e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958807392 556 PDPPLAPTLISRTKNSLNLQWKGCNDNGSKISSFLLEWDEGIGEDFKSCYTGPLKQ--HKLFKLSPSTKYSFRLAAKNHF 633
Cdd:cd00063 1 PSPPTNLRVTDVTSTSVTLSWTPPEDDGGPITGYVVEYREKGSGDWKEVEVTPGSEtsYTLTGLKPGTEYEFRVRAVNGG 80
|
90
....*....|...
gi 1958807392 634 GCSNFSETAVFYT 646
Cdd:cd00063 81 GESPPSESVTVTT 93
|
|
| FN3 |
COG3401 |
Fibronectin type 3 domain [General function prediction only]; |
810-1161 |
9.40e-13 |
|
Fibronectin type 3 domain [General function prediction only];
Pssm-ID: 442628 [Multi-domain] Cd Length: 603 Bit Score: 72.73 E-value: 9.40e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958807392 810 YDDLQPGTTYKLRVFCTSPAGQSRPSDVLTIQTPALPPESCSSqpLHSKSKGRDANLLDNRSVngkSEAPVRGkkakgph 889
Cdd:COG3401 196 GGDIEPGTTYYYRVAATDTGGESAPSNEVSVTTPTTPPSAPTG--LTATADTPGSVTLSWDPV---TESDATG------- 263
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958807392 890 dkkecpssektcaipkcngaeiidYRLQWGQVE-ESMHLIYTGPCLRYEVKGLIPATTYFCRVQAVNIVGV-GMFGGTAK 967
Cdd:COG3401 264 ------------------------YRVYRSNSGdGPFTKVATVTTTSYTDTGLTNGTTYYYRVTAVDAAGNeSAPSNVVS 319
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958807392 968 VTTPGTVPAMVPMLqevenKVPAKQSSTcIAIRWEEPDchGSQITGYNIEYGDK------KIVTVKRVTEYVLKNLQPNT 1041
Cdd:COG3401 320 VTTDLTPPAAPSGL-----TATAVGSSS-ITLSWTASS--DADVTGYNVYRSTSgggtytKIAETVTTTSYTDTGLTPGT 391
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958807392 1042 TYRIRIQAINHYGLSPFSPSIRCKTKPLPPEPPQLNCVVYGHQSLRLKWGTVSSKKSLANFISYNLLMEDRSGRFSVIYR 1121
Cdd:COG3401 392 TYYYKVTAVDAAGNESAPSEEVSATTASAASGESLTASVDAVPLTDVAGATAAASAASNPGVSAAVLADGGDTGNAVPFT 471
|
330 340 350 360
....*....|....*....|....*....|....*....|
gi 1958807392 1122 GTDVTHKVQKLTEYTQYKFKIQACNEAGEGPESDIYTFTT 1161
Cdd:COG3401 472 TTSSTVTATTTDTTTANLSVTTGSLVGGSGASSVTNSVSV 511
|
|
| FN3 |
cd00063 |
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ... |
651-743 |
4.16e-12 |
|
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.
Pssm-ID: 238020 [Multi-domain] Cd Length: 93 Bit Score: 63.28 E-value: 4.16e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958807392 651 PSAPLPPKLKEAGVYSLSLEWCAPTNPNPNDTlTYVLEMEEAKSGLGFK-PKYNGEDLSCTVKNLQRNTTYKFRIFAYNL 729
Cdd:cd00063 1 PSPPTNLRVTDVTSTSVTLSWTPPEDDGGPIT-GYVVEYREKGSGDWKEvEVTPGSETSYTLTGLKPGTEYEFRVRAVNG 79
|
90
....*....|....
gi 1958807392 730 EGRSNPSGEVKYTT 743
Cdd:cd00063 80 GGESPPSESVTVTT 93
|
|
| fn3 |
pfam00041 |
Fibronectin type III domain; |
992-1059 |
7.69e-12 |
|
Fibronectin type III domain;
Pssm-ID: 394996 [Multi-domain] Cd Length: 85 Bit Score: 62.43 E-value: 7.69e-12
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1958807392 992 QSSTCIAIRWEEPDCHGSQITGYNIEY------GDKKIVTVKRVT-EYVLKNLQPNTTYRIRIQAINHYGLSPFS 1059
Cdd:pfam00041 11 VTSTSLTVSWTPPPDGNGPITGYEVEYrpknsgEPWNEITVPGTTtSVTLTGLKPGTEYEVRVQAVNGGGEGPPS 85
|
|
| FN3 |
COG3401 |
Fibronectin type 3 domain [General function prediction only]; |
336-749 |
2.97e-11 |
|
Fibronectin type 3 domain [General function prediction only];
Pssm-ID: 442628 [Multi-domain] Cd Length: 603 Bit Score: 67.72 E-value: 2.97e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958807392 336 SDNSNDITSPSINTYDLVTSDETHEPPDAKSIPSYTSESTCNALITENAQTCSSNKDDLRPSGAATISN-NTRAYTEDNP 414
Cdd:COG3401 27 SKAGGSGKTILVYLAVVLSVTTKESPGTLLVAAGLSSGGGLGTGGRAGTTSGVAAVAVAAAPPTATGLTtLTGSGSVGGA 106
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958807392 415 GETETNMGAGDSKQISDENQRKRhssnasvrehNTEYGTQPCCSNIEKPVVSNIQTRSATVSWALNSAEKYDINSPMkfe 494
Cdd:COG3401 107 TNTGLTSSDEVPSPAVGTATTAT----------AVAGGAATAGTYALGAGLYGVDGANASGTTASSVAGAGVVVSPD--- 173
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958807392 495 ltLSSSGKNGNYKNIYTGDGVTVVLHDLQPCTVYFLRVAIIRDGEHRNVSEVVSFTTPGCEPDPPLAPTLISRTKNSLNL 574
Cdd:COG3401 174 --TSATAAVATTSLTVTSTTLVDGGGDIEPGTTYYYRVAATDTGGESAPSNEVSVTTPTTPPSAPTGLTATADTPGSVTL 251
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958807392 575 QWKGCNDNGskISSFLLEWDEGIGEDFKSCYTGPLKQHKLFKLSPSTKYSFRLAAKNHFGC-SNFSETAVFYTSGNTPSA 653
Cdd:COG3401 252 SWDPVTESD--ATGYRVYRSNSGDGPFTKVATVTTTSYTDTGLTNGTTYYYRVTAVDAAGNeSAPSNVVSVTTDLTPPAA 329
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958807392 654 PLPPKLKEAGVYSLSLEWCAPTNPnpnDTLTYVLEMEEAKSGLGFKPKYNGEDLSCTVKNLQRNTTYKFRIFAYNLEGR- 732
Cdd:COG3401 330 PSGLTATAVGSSSITLSWTASSDA---DVTGYNVYRSTSGGGTYTKIAETVTTTSYTDTGLTPGTTYYYKVTAVDAAGNe 406
|
410
....*....|....*..
gi 1958807392 733 SNPSGEVKYTTRPARPG 749
Cdd:COG3401 407 SAPSEEVSATTASAASG 423
|
|
| FN3 |
smart00060 |
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ... |
993-1056 |
3.11e-11 |
|
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.
Pssm-ID: 214495 [Multi-domain] Cd Length: 83 Bit Score: 60.71 E-value: 3.11e-11
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1958807392 993 SSTCIAIRWEEP--DCHGSQITGYNIEYGD-----KKIVTVKRVTEYVLKNLQPNTTYRIRIQAINHYGLS 1056
Cdd:smart00060 13 TSTSVTLSWEPPpdDGITGYIVGYRVEYREegsewKEVNVTPSSTSYTLTGLKPGTEYEFRVRAVNGAGEG 83
|
|
| FN3 |
COG3401 |
Fibronectin type 3 domain [General function prediction only]; |
641-1051 |
5.09e-11 |
|
Fibronectin type 3 domain [General function prediction only];
Pssm-ID: 442628 [Multi-domain] Cd Length: 603 Bit Score: 66.95 E-value: 5.09e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958807392 641 TAVFYTSGNTPSAPLPPKLKEAGVYSLSLEWCAPTNPNPNDTLTYVLEMEEAKSGLGFKPKYNGEDLSCTVKNlqrNTTY 720
Cdd:COG3401 129 TAVAGGAATAGTYALGAGLYGVDGANASGTTASSVAGAGVVVSPDTSATAAVATTSLTVTSTTLVDGGGDIEP---GTTY 205
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958807392 721 KFRIFAYNLEGRSNPSGEVKYTTrPARPgcPNKPH--VVGTIHARQVTIGWDlpkDNGGMNISSYSLEVCENSDAGnlWK 798
Cdd:COG3401 206 YYRVAATDTGGESAPSNEVSVTT-PTTP--PSAPTglTATADTPGSVTLSWD---PVTESDATGYRVYRSNSGDGP--FT 277
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958807392 799 IIYSGTLQEFLYDDLQPGTTYKLRVFCTSPAG-QSRPSDVLTIQTPALPPescssqplhskskgrdanlldnrsvngkse 877
Cdd:COG3401 278 KVATVTTTSYTDTGLTNGTTYYYRVTAVDAAGnESAPSNVVSVTTDLTPP------------------------------ 327
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958807392 878 APVRGKKAKGPHDKK-----ECPSSEKtcaipkcngaeIIDYRLQWGQVEE-SMHLIY-TGPCLRYEVKGLIPATTYFCR 950
Cdd:COG3401 328 AAPSGLTATAVGSSSitlswTASSDAD-----------VTGYNVYRSTSGGgTYTKIAeTVTTTSYTDTGLTPGTTYYYK 396
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958807392 951 VQAVNIVGV-GMFGGTAKVTTPGTVPAMVPMLQEVENKVPAKQSSTcIAIRWEEPDCHGSQITGYNIEYGDKKIVTVKRV 1029
Cdd:COG3401 397 VTAVDAAGNeSAPSEEVSATTASAASGESLTASVDAVPLTDVAGAT-AAASAASNPGVSAAVLADGGDTGNAVPFTTTSS 475
|
410 420
....*....|....*....|..
gi 1958807392 1030 TEYVLKNLQPNTTYRIRIQAIN 1051
Cdd:COG3401 476 TVTATTTDTTTANLSVTTGSLV 497
|
|
| FN3 |
cd00063 |
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ... |
748-842 |
2.94e-10 |
|
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.
Pssm-ID: 238020 [Multi-domain] Cd Length: 93 Bit Score: 58.28 E-value: 2.94e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958807392 748 PGCPNKPHVVgTIHARQVTIGWDLPKDNGGmNISSYSLEVCENSDAGnlWKII--YSGTLQEFLYDDLQPGTTYKLRVFC 825
Cdd:cd00063 1 PSPPTNLRVT-DVTSTSVTLSWTPPEDDGG-PITGYVVEYREKGSGD--WKEVevTPGSETSYTLTGLKPGTEYEFRVRA 76
|
90
....*....|....*..
gi 1958807392 826 TSPAGQSRPSDVLTIQT 842
Cdd:cd00063 77 VNGGGESPPSESVTVTT 93
|
|
| FN3 |
COG3401 |
Fibronectin type 3 domain [General function prediction only]; |
1012-1168 |
4.90e-10 |
|
Fibronectin type 3 domain [General function prediction only];
Pssm-ID: 442628 [Multi-domain] Cd Length: 603 Bit Score: 63.87 E-value: 4.90e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958807392 1012 TGYNIEYGDKKIVTVKRVTEYVLKNLQPNTTYRIRIQAINHYGLSPFSPSIRCKTKPLPPEPPQ-LNCVVYGHQSLRLKW 1090
Cdd:COG3401 174 TSATAAVATTSLTVTSTTLVDGGGDIEPGTTYYYRVAATDTGGESAPSNEVSVTTPTTPPSAPTgLTATADTPGSVTLSW 253
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958807392 1091 GTVSSKkslaNFISYNLL-MEDRSGRFSVIYRGTDVTHKVQKLTEYTQYKFKIQACNEAG-EGPESDIYTFTTTKSPPTA 1168
Cdd:COG3401 254 DPVTES----DATGYRVYrSNSGDGPFTKVATVTTTSYTDTGLTNGTTYYYRVTAVDAAGnESAPSNVVSVTTDLTPPAA 329
|
|
| FN3 |
smart00060 |
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ... |
651-733 |
8.87e-09 |
|
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.
Pssm-ID: 214495 [Multi-domain] Cd Length: 83 Bit Score: 53.77 E-value: 8.87e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958807392 651 PSAPLPPKLKEAGVYSLSLEWCAPTNPNPNDTLTYVLEMEEAKSGLGFKPKYNGEDLSCTVKNLQRNTTYKFRIFAYNLE 730
Cdd:smart00060 1 PSPPSNLRVTDVTSTSVTLSWEPPPDDGITGYIVGYRVEYREEGSEWKEVNVTPSSTSYTLTGLKPGTEYEFRVRAVNGA 80
|
...
gi 1958807392 731 GRS 733
Cdd:smart00060 81 GEG 83
|
|
| FN3 |
cd00063 |
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ... |
1070-1161 |
1.15e-08 |
|
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.
Pssm-ID: 238020 [Multi-domain] Cd Length: 93 Bit Score: 53.65 E-value: 1.15e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958807392 1070 PPEPPQLNCVVYGHQSLRLKWGTVSSKKSlaNFISYNLLMEDRSGRFSVIYRGTDVT---HKVQKLTEYTQYKFKIQACN 1146
Cdd:cd00063 1 PSPPTNLRVTDVTSTSVTLSWTPPEDDGG--PITGYVVEYREKGSGDWKEVEVTPGSetsYTLTGLKPGTEYEFRVRAVN 78
|
90
....*....|....*
gi 1958807392 1147 EAGEGPESDIYTFTT 1161
Cdd:cd00063 79 GGGESPPSESVTVTT 93
|
|
| FN3 |
smart00060 |
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ... |
556-636 |
5.35e-08 |
|
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.
Pssm-ID: 214495 [Multi-domain] Cd Length: 83 Bit Score: 51.46 E-value: 5.35e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958807392 556 PDPPLAPTLISRTKNSLNLQWKGCNDNG--SKISSFLLEWDEGIGEDFKSCYTGPLKQHKLFKLSPSTKYSFRLAAKNHF 633
Cdd:smart00060 1 PSPPSNLRVTDVTSTSVTLSWEPPPDDGitGYIVGYRVEYREEGSEWKEVNVTPSSTSYTLTGLKPGTEYEFRVRAVNGA 80
|
...
gi 1958807392 634 GCS 636
Cdd:smart00060 81 GEG 83
|
|
| fn3 |
pfam00041 |
Fibronectin type III domain; |
557-639 |
2.86e-07 |
|
Fibronectin type III domain;
Pssm-ID: 394996 [Multi-domain] Cd Length: 85 Bit Score: 49.34 E-value: 2.86e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958807392 557 DPPLAPTLISRTKNSLNLQWKGCNDNGSKISSFLLEWDEGIGEDFKSCYT--GPLKQHKLFKLSPSTKYSFRLAAKNHFG 634
Cdd:pfam00041 1 SAPSNLTVTDVTSTSLTVSWTPPPDGNGPITGYEVEYRPKNSGEPWNEITvpGTTTSVTLTGLKPGTEYEVRVQAVNGGG 80
|
....*
gi 1958807392 635 CSNFS 639
Cdd:pfam00041 81 EGPPS 85
|
|
| FN3 |
smart00060 |
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ... |
1070-1151 |
7.43e-07 |
|
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.
Pssm-ID: 214495 [Multi-domain] Cd Length: 83 Bit Score: 48.38 E-value: 7.43e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958807392 1070 PPEPPQLNCVVYGHQSLRLKWGTVSSKKSLANFISYNLLMEDRSGRFSVIYRGTDVT-HKVQKLTEYTQYKFKIQACNEA 1148
Cdd:smart00060 1 PSPPSNLRVTDVTSTSVTLSWEPPPDDGITGYIVGYRVEYREEGSEWKEVNVTPSSTsYTLTGLKPGTEYEFRVRAVNGA 80
|
...
gi 1958807392 1149 GEG 1151
Cdd:smart00060 81 GEG 83
|
|
| FN3 |
COG3401 |
Fibronectin type 3 domain [General function prediction only]; |
266-743 |
1.07e-06 |
|
Fibronectin type 3 domain [General function prediction only];
Pssm-ID: 442628 [Multi-domain] Cd Length: 603 Bit Score: 53.08 E-value: 1.07e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958807392 266 TLCPYTVDTAPSTNTDTSPLDTYSLNTVLKACTTDSTPRNMADNIPD---------TNTTDRNTSSGHSPSNSTSNAFCS 336
Cdd:COG3401 39 YLAVVLSVTTKESPGTLLVAAGLSSGGGLGTGGRAGTTSGVAAVAVAaapptatglTTLTGSGSVGGATNTGLTSSDEVP 118
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958807392 337 DNSNDITSPSINTYDLVTSDETHEPPDAKSIPSYTSESTCNALITENAqtcSSNKDDLRPSGAATISNNTRAYTEDNPGE 416
Cdd:COG3401 119 SPAVGTATTATAVAGGAATAGTYALGAGLYGVDGANASGTTASSVAGA---GVVVSPDTSATAAVATTSLTVTSTTLVDG 195
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958807392 417 TETNMgAGDSKQISDENQRKRHSSNASVREHNTEYGTQPccsniEKP---VVSNIQTRSATVSW---ALNSAEKYDInsp 490
Cdd:COG3401 196 GGDIE-PGTTYYYRVAATDTGGESAPSNEVSVTTPTTPP-----SAPtglTATADTPGSVTLSWdpvTESDATGYRV--- 266
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958807392 491 mkfeltLSSSGKNGNYKNIYTGDGVTVVLHDLQPCTVYFLRV-AIIRDGEHRNVSEVVSFTTPGCEPDPPLAPTLISRTK 569
Cdd:COG3401 267 ------YRSNSGDGPFTKVATVTTTSYTDTGLTNGTTYYYRVtAVDAAGNESAPSNVVSVTTDLTPPAAPSGLTATAVGS 340
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958807392 570 NSLNLQWKGCNDNGskISSFLLEWDEGIGEDFKSCYTGPLK-QHKLFKLSPSTKYSFRLAAKNHFGCSNFSETAVFYTSG 648
Cdd:COG3401 341 SSITLSWTASSDAD--VTGYNVYRSTSGGGTYTKIAETVTTtSYTDTGLTPGTTYYYKVTAVDAAGNESAPSEEVSATTA 418
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958807392 649 NTPSAPLPPKLKEAGVYSLSLEWCAPTNPNPNDTLTYVLEMEEAKSGLGFKPKYNGEDLSCTVKNLQRNTTYKFRIFAYN 728
Cdd:COG3401 419 SAASGESLTASVDAVPLTDVAGATAAASAASNPGVSAAVLADGGDTGNAVPFTTTSSTVTATTTDTTTANLSVTTGSLVG 498
|
490
....*....|....*
gi 1958807392 729 LEGRSNPSGEVKYTT 743
Cdd:COG3401 499 GSGASSVTNSVSVIG 513
|
|
| FN3 |
smart00060 |
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ... |
748-832 |
8.16e-06 |
|
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.
Pssm-ID: 214495 [Multi-domain] Cd Length: 83 Bit Score: 45.30 E-value: 8.16e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958807392 748 PGCPNKPHVVgTIHARQVTIGWDLPKDNGGMN-ISSYSLEvceNSDAGNLWKIIYSGTLQ-EFLYDDLQPGTTYKLRVFC 825
Cdd:smart00060 1 PSPPSNLRVT-DVTSTSVTLSWEPPPDDGITGyIVGYRVE---YREEGSEWKEVNVTPSStSYTLTGLKPGTEYEFRVRA 76
|
....*..
gi 1958807392 826 TSPAGQS 832
Cdd:smart00060 77 VNGAGEG 83
|
|
| fn3 |
pfam00041 |
Fibronectin type III domain; |
652-736 |
1.31e-05 |
|
Fibronectin type III domain;
Pssm-ID: 394996 [Multi-domain] Cd Length: 85 Bit Score: 44.71 E-value: 1.31e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958807392 652 SAPLPPKLKEAGVYSLSLEWCAPTNPNPNDTlTYVLEMEEAKSGLGFKPKYNGEDL-SCTVKNLQRNTTYKFRIFAYNLE 730
Cdd:pfam00041 1 SAPSNLTVTDVTSTSLTVSWTPPPDGNGPIT-GYEVEYRPKNSGEPWNEITVPGTTtSVTLTGLKPGTEYEVRVQAVNGG 79
|
....*.
gi 1958807392 731 GRSNPS 736
Cdd:pfam00041 80 GEGPPS 85
|
|
| FN3 |
cd00063 |
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ... |
904-970 |
1.73e-05 |
|
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.
Pssm-ID: 238020 [Multi-domain] Cd Length: 93 Bit Score: 44.79 E-value: 1.73e-05
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958807392 904 PKCNGAEIIDYRLQWGQVEESMHLIYTGPC---LRYEVKGLIPATTYFCRVQAVNIVGVGMFGGTAKVTT 970
Cdd:cd00063 24 PEDDGGPITGYVVEYREKGSGDWKEVEVTPgseTSYTLTGLKPGTEYEFRVRAVNGGGESPPSESVTVTT 93
|
|
| fn3 |
pfam00041 |
Fibronectin type III domain; |
904-962 |
2.09e-05 |
|
Fibronectin type III domain;
Pssm-ID: 394996 [Multi-domain] Cd Length: 85 Bit Score: 44.33 E-value: 2.09e-05
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1958807392 904 PKCNGAEIIDYRLQWGQV---EESMHLIYTGPCLRYEVKGLIPATTYFCRVQAVNIVGVGMF 962
Cdd:pfam00041 23 PPDGNGPITGYEVEYRPKnsgEPWNEITVPGTTTSVTLTGLKPGTEYEVRVQAVNGGGEGPP 84
|
|
| fn3 |
pfam00041 |
Fibronectin type III domain; |
762-835 |
2.23e-04 |
|
Fibronectin type III domain;
Pssm-ID: 394996 [Multi-domain] Cd Length: 85 Bit Score: 41.25 E-value: 2.23e-04
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1958807392 762 ARQVTIGWDLPKDNGGmNISSYSLEvCENSDAGNLWK-IIYSGTLQEFLYDDLQPGTTYKLRVFCTSPAGQSRPS 835
Cdd:pfam00041 13 STSLTVSWTPPPDGNG-PITGYEVE-YRPKNSGEPWNeITVPGTTTSVTLTGLKPGTEYEVRVQAVNGGGEGPPS 85
|
|
| Pur_ac_phosph_N |
pfam16656 |
Purple acid Phosphatase, N-terminal domain; This domain is found at the N-terminus of Purple ... |
470-551 |
2.78e-04 |
|
Purple acid Phosphatase, N-terminal domain; This domain is found at the N-terminus of Purple acid phosphatase proteins.
Pssm-ID: 465220 [Multi-domain] Cd Length: 93 Bit Score: 41.24 E-value: 2.78e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958807392 470 TRSATVSWALNSAEK-----YDINSpmkFELTLSSSGKNGNYKNIYTGDGV--TVVLHDLQPCTVYFLRVaiiRDGEHRn 542
Cdd:pfam16656 12 STSMTVSWVTPSAVTspvvqYGTSS---SALTSTATATSSTYTTGDGGTGYihRATLTGLEPGTTYYYRV---GDDNGG- 84
|
....*....
gi 1958807392 543 VSEVVSFTT 551
Cdd:pfam16656 85 WSEVYSFTT 93
|
|
| FN3 |
smart00060 |
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ... |
907-960 |
5.60e-04 |
|
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.
Pssm-ID: 214495 [Multi-domain] Cd Length: 83 Bit Score: 39.91 E-value: 5.60e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*
gi 1958807392 907 NGAEIIDYRLQWGQVEES-MHLIYTGPCLRYEVKGLIPATTYFCRVQAVNIVGVG 960
Cdd:smart00060 29 ITGYIVGYRVEYREEGSEwKEVNVTPSSTSYTLTGLKPGTEYEFRVRAVNGAGEG 83
|
|
| fn3 |
pfam00041 |
Fibronectin type III domain; |
1071-1154 |
6.75e-04 |
|
Fibronectin type III domain;
Pssm-ID: 394996 [Multi-domain] Cd Length: 85 Bit Score: 39.71 E-value: 6.75e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958807392 1071 PEPPQLNCVVYGHQSLRLKWGTVSSKKSlaNFISYNLLMEDRSG-----RFSViyRGTDVTHKVQKLTEYTQYKFKIQAC 1145
Cdd:pfam00041 1 SAPSNLTVTDVTSTSLTVSWTPPPDGNG--PITGYEVEYRPKNSgepwnEITV--PGTTTSVTLTGLKPGTEYEVRVQAV 76
|
....*....
gi 1958807392 1146 NEAGEGPES 1154
Cdd:pfam00041 77 NGGGEGPPS 85
|
|
| COG4733 |
COG4733 |
Phage-related protein, tail protein J [Mobilome: prophages, transposons]; |
912-1054 |
8.49e-04 |
|
Phage-related protein, tail protein J [Mobilome: prophages, transposons];
Pssm-ID: 443767 [Multi-domain] Cd Length: 978 Bit Score: 43.78 E-value: 8.49e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958807392 912 IDYRLQWGQVEESMHLIYTGPCLRYEVKGlIPATTYFCRVQAVNIVGV-GMFGGTAKVTTPG--TVPAMVPMLQevenkv 988
Cdd:COG4733 565 VAYEVEWRRDDGNWVSVPRTSGTSFEVPG-IYAGDYEVRVRAINALGVsSAWAASSETTVTGktAPPPAPTGLT------ 637
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1958807392 989 pAKQSSTCIAIRWEEPDchGSQITGYNIEYGD-------KKIVTVKRVTEYVLKNLQPNTTYRIRIQAINHYG 1054
Cdd:COG4733 638 -ATGGLGGITLSWSFPV--DADTLRTEIRYSTtgdwasaTVAQALYPGNTYTLAGLKAGQTYYYRARAVDRSG 707
|
|
| ROM1 |
COG5422 |
RhoGEF, Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases [Signal transduction ... |
229-520 |
5.57e-03 |
|
RhoGEF, Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases [Signal transduction mechanisms];
Pssm-ID: 227709 [Multi-domain] Cd Length: 1175 Bit Score: 41.42 E-value: 5.57e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958807392 229 SKKKIRDRQLGeHKISSTFSDTPLLlnkvidisaPSGTLCPYTVDTAPSTNTDTSPLDTYSLNTVlkacttdsTPRNMAD 308
Cdd:COG5422 59 SKESFGKYALG-HQIFSSFSSSPKL---------FQRRNSAGPITHSPSATSSTSSLNSNDGDQF--------SPASDSL 120
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958807392 309 NIPDTNTTDR---NTSSGhSPSNSTSNAFCSDNSNDITSPSINTYDlvTSDETHEPPDAKSIPSYTSEStcnalitenAQ 385
Cdd:COG5422 121 SFNPSSTQSRkdsGPGDG-SPVQKRKNPLLPSSSTHGTHPPIVFTD--NNGSHAGAPNARSRKEIPSLG---------SQ 188
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958807392 386 TCSSNKDDLRPSGAATISNNTRAYTEDNPGETETNMGAGDSKQISDENQRKRHSSNASvrEHNTEYGTQPCCSNIEkpvV 465
Cdd:COG5422 189 SMQLPSPHFRQKFSSSDTSNGFSYPSIRKNSRHSSNSMPSFPHSSTAVLLKRHSGSSG--ASLISSNITPSSSNSE---A 263
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*..
gi 1958807392 466 SNIQTRSATVSWALNSAekydINSPMKFELTLSSSGKNGN-YKNIYTGD-GVTVVLH 520
Cdd:COG5422 264 MSTSSKRPYIYPALLSR----VAVEFKMRLQLGDHKKDGLlYRDAFTGSeAVDVLML 316
|
|
| |
