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Conserved domains on  [gi|1958751377|ref|XP_038958528|]
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ETS-related transcription factor Elf-2 isoform X6 [Rattus norvegicus]

Protein Classification

ETS domain-containing protein; ETS domain-containing protein; erythroblast transformation specific family transcription factor( domain architecture ID 13622038)

ETS (erythroblast transformation specific) domain-containing protein may function as a transcriptional regulator; ETS (erythroblast transformation specific) domain-containing protein may function as a transcriptional regulator; erythroblast transformation specific (ETS) family transcription factor may be involved in the regulation of immunoglobulin heavy-chain gene expression

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Ets pfam00178
Ets-domain;
74-154 5.28e-45

Ets-domain;


:

Pssm-ID: 459700  Cd Length: 80  Bit Score: 151.49  E-value: 5.28e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958751377  74 YLWEFLLDLLQDKnTCPRYIKWTQREKGIFKLVDSKAVSKLWGKHKNKPDMNYETMGRALRYYYQRGILAKVEGQRLVYQ 153
Cdd:pfam00178   1 QLWQFLLDLLTDP-EYSDIIKWTDKEEGEFRLVDPEAVARLWGKRKGNPKMTYEKLSRALRYYYKKGILEKVPGKRLTYR 79


                  .
gi 1958751377 154 F 154
Cdd:pfam00178  80 F 80
Herpes_BLLF1 super family cl37540
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ...
 214-393 1.91e-04

Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.


The actual alignment was detected with superfamily member pfam05109:

Pssm-ID: 282904 [Multi-domain]  Cd Length: 886  Bit Score: 44.14  E-value: 1.91e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958751377 214 SRAEKGVTRVVNITSPAHDASSRCPTTTAPVSAAAAPRTVRVAMQVPVVMTSLGQKISTVAVQ--SVNAGTPLITSTSPA 291
Cdd:pfam05109 501 SKAPDMTSPTSAVTTPTPNATSPTPAVTTPTPNATSPTLGKTSPTSAVTTPTPNATSPTPAVTtpTPNATIPTLGKTSPT 580

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958751377 292 TASSPKVVIQTVPTVMPASAE-NGDRITM---QPAKIITIPATQLAQCQLQTKSNLTGSGSISLVGTPLAV-RALTPVSI 366
Cdd:pfam05109 581 SAVTTPTPNATSPTVGETSPQaNTTNHTLggtSSTPVVTSPPKNATSAVTTGQHNITSSSTSSMSLRPSSIsETLSPSTS 660

                         170       180
                  ....*....|....*....|....*..
gi 1958751377 367 AHGTPVMRLSVPAQQASGQTPPRVISA 393
Cdd:pfam05109 661 DNSTSHMPLLTSAHPTGGENITQVTPA 687
 
Name Accession Description Interval E-value
Ets pfam00178
Ets-domain;
74-154 5.28e-45

Ets-domain;


Pssm-ID: 459700  Cd Length: 80  Bit Score: 151.49  E-value: 5.28e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958751377  74 YLWEFLLDLLQDKnTCPRYIKWTQREKGIFKLVDSKAVSKLWGKHKNKPDMNYETMGRALRYYYQRGILAKVEGQRLVYQ 153
Cdd:pfam00178   1 QLWQFLLDLLTDP-EYSDIIKWTDKEEGEFRLVDPEAVARLWGKRKGNPKMTYEKLSRALRYYYKKGILEKVPGKRLTYR 79


                  .
gi 1958751377 154 F 154
Cdd:pfam00178  80 F 80
ETS smart00413
erythroblast transformation specific domain; variation of the helix-turn-helix motif
 72-154 6.09e-45

erythroblast transformation specific domain; variation of the helix-turn-helix motif


Pssm-ID: 197710  Cd Length: 87  Bit Score: 151.65  E-value: 6.09e-45
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958751377   72 TTYLWEFLLDLLQDKNTcPRYIKWTQREKGIFKLVDSKAVSKLWGKHKNKPDMNYETMGRALRYYYQRGILAKVEGQRLV 151
Cdd:smart00413   1 GIQLWQFLLDLLLDPEN-SDIIKWTDRDEGEFKLVDPEEVARLWGQRKNKPNMNYEKLSRALRYYYKKNILEKVPGKRLV 79


                   ...
gi 1958751377  152 YQF 154
Cdd:smart00413  80 YKF 82
Herpes_BLLF1 pfam05109
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ...
 214-393 1.91e-04

Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.


Pssm-ID: 282904 [Multi-domain]  Cd Length: 886  Bit Score: 44.14  E-value: 1.91e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958751377 214 SRAEKGVTRVVNITSPAHDASSRCPTTTAPVSAAAAPRTVRVAMQVPVVMTSLGQKISTVAVQ--SVNAGTPLITSTSPA 291
Cdd:pfam05109 501 SKAPDMTSPTSAVTTPTPNATSPTPAVTTPTPNATSPTLGKTSPTSAVTTPTPNATSPTPAVTtpTPNATIPTLGKTSPT 580

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958751377 292 TASSPKVVIQTVPTVMPASAE-NGDRITM---QPAKIITIPATQLAQCQLQTKSNLTGSGSISLVGTPLAV-RALTPVSI 366
Cdd:pfam05109 581 SAVTTPTPNATSPTVGETSPQaNTTNHTLggtSSTPVVTSPPKNATSAVTTGQHNITSSSTSSMSLRPSSIsETLSPSTS 660

                         170       180
                  ....*....|....*....|....*..
gi 1958751377 367 AHGTPVMRLSVPAQQASGQTPPRVISA 393
Cdd:pfam05109 661 DNSTSHMPLLTSAHPTGGENITQVTPA 687
 
Name Accession Description Interval E-value
Ets pfam00178
Ets-domain;
74-154 5.28e-45

Ets-domain;


Pssm-ID: 459700  Cd Length: 80  Bit Score: 151.49  E-value: 5.28e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958751377  74 YLWEFLLDLLQDKnTCPRYIKWTQREKGIFKLVDSKAVSKLWGKHKNKPDMNYETMGRALRYYYQRGILAKVEGQRLVYQ 153
Cdd:pfam00178   1 QLWQFLLDLLTDP-EYSDIIKWTDKEEGEFRLVDPEAVARLWGKRKGNPKMTYEKLSRALRYYYKKGILEKVPGKRLTYR 79


                  .
gi 1958751377 154 F 154
Cdd:pfam00178  80 F 80
ETS smart00413
erythroblast transformation specific domain; variation of the helix-turn-helix motif
 72-154 6.09e-45

erythroblast transformation specific domain; variation of the helix-turn-helix motif


Pssm-ID: 197710  Cd Length: 87  Bit Score: 151.65  E-value: 6.09e-45
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958751377   72 TTYLWEFLLDLLQDKNTcPRYIKWTQREKGIFKLVDSKAVSKLWGKHKNKPDMNYETMGRALRYYYQRGILAKVEGQRLV 151
Cdd:smart00413   1 GIQLWQFLLDLLLDPEN-SDIIKWTDRDEGEFKLVDPEEVARLWGQRKNKPNMNYEKLSRALRYYYKKNILEKVPGKRLV 79


                   ...
gi 1958751377  152 YQF 154
Cdd:smart00413  80 YKF 82
Herpes_BLLF1 pfam05109
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ...
 214-393 1.91e-04

Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.


Pssm-ID: 282904 [Multi-domain]  Cd Length: 886  Bit Score: 44.14  E-value: 1.91e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958751377 214 SRAEKGVTRVVNITSPAHDASSRCPTTTAPVSAAAAPRTVRVAMQVPVVMTSLGQKISTVAVQ--SVNAGTPLITSTSPA 291
Cdd:pfam05109 501 SKAPDMTSPTSAVTTPTPNATSPTPAVTTPTPNATSPTLGKTSPTSAVTTPTPNATSPTPAVTtpTPNATIPTLGKTSPT 580

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958751377 292 TASSPKVVIQTVPTVMPASAE-NGDRITM---QPAKIITIPATQLAQCQLQTKSNLTGSGSISLVGTPLAV-RALTPVSI 366
Cdd:pfam05109 581 SAVTTPTPNATSPTVGETSPQaNTTNHTLggtSSTPVVTSPPKNATSAVTTGQHNITSSSTSSMSLRPSSIsETLSPSTS 660

                         170       180
                  ....*....|....*....|....*..
gi 1958751377 367 AHGTPVMRLSVPAQQASGQTPPRVISA 393
Cdd:pfam05109 661 DNSTSHMPLLTSAHPTGGENITQVTPA 687
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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