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Conserved domains on  [gi|1958764989|ref|XP_038962161|]
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centriolin isoform X5 [Rattus norvegicus]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PPP1R42 super family cl42388
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 89-261 2.87e-26

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


The actual alignment was detected with superfamily member cd21340:

Pssm-ID: 455733 [Multi-domain]  Cd Length: 220  Bit Score: 109.11  E-value: 2.87e-26
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989   89 KKLTKQDNLALVKSL-------NlslskdggkKFRYIENLEKCVKLEVLNLSYNLIAKIEKVDKLLRLRELNLSYNKISK 161
Cdd:cd21340     12 KNITKIDNLSLCKNLkvlylydN---------KITKIENLEFLTNLTHLYLQNNQIEKIENLENLVNLKKLYLGGNRISV 82

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  162 IEGLENMCN------------------------------LQKLNLAGNEIEHIpgWFSKKLKSLRVLNLKGNKISSLQDV 211
Cdd:cd21340     83 VEGLENLTNleelhienqrlppgekltfdprslaalsnsLRVLNISGNNIDSL--EPLAPLRNLEQLDASNNQISDLEEL 160

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1958764989  212 SK-LKPLQDLTSLTLIDNPVVALPHYLQFIIFHLRSLESLEGQPVTTQDRQ 261
Cdd:cd21340    161 LDlLSSWPSLRELDLTGNPVCKKPKYRDKIILASKSLEVLDGKEITDTERQ 211
Smc super family cl34174
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 452-1047 3.68e-25

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


The actual alignment was detected with superfamily member COG1196:

Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 114.65  E-value: 3.68e-25
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  452 RLSELHHEIEAAEQ-KVLRATQEFKQLEEAIRQKKISEAEKDLLLKQLSGRLRHLNKLRQEALDLEAQLEKQRKEIAEKH 530
Cdd:COG1196    201 QLEPLERQAEKAERyRELKEELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELE 280

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  531 EEINSAQLATDLLdskdpkqshmKAQKRGKEQQLDIMNKQYTQLESRLDEILCRIATETEEIKDLEQQLTDGQIAANEAL 610
Cdd:COG1196    281 LELEEAQAEEYEL----------LAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAE 350

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  611 KKDLEgvisglqeylgtikgQAAQAQNECRKLQDEKETLLQRLTEVKQEKDELEIVAMDAENMRKELAELENALQEQHEV 690
Cdd:COG1196    351 EELEE---------------AEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLER 415

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  691 NASLQQAQGDLSAYETELETQLK-LKDAETSQLKQELENLVRRTQLEQSVLQTELEKERQSLRDALGKAQSSEEKQQENS 769
Cdd:COG1196    416 LERLEEELEELEEALAELEEEEEeEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLL 495

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  770 ELRAQLKQLQDDNSLLKKQLKDFQSHLNHVVDGLIHPEEVAARVDELRkrlkLGAGEMRIHSPSDVLGKSLADLQKQ--- 846
Cdd:COG1196    496 LLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAA----LAAALQNIVVEDDEVAAAAIEYLKAaka 571

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  847 ----FSEILARSQWEKEEAQVRERKLHEEMALQQEKLANGQEEFKQACERALEARIkfDKRQHNARIQQLENEIHYLQEN 922
Cdd:COG1196    572 gratFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTL--VAARLEAALRRAVTLAGRLREV 649

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  923 LKSMEKIQGLTDLQLQEADEEKERILAQLQELEKKKRREDARSQEQFLGLDTELKSLKKAVAASDKLAAAELTIAKEQLK 1002
Cdd:COG1196    650 TLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQ 729

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|....*
gi 1958764989 1003 SLHgTVMRINQERAEELQEAERSSREAMQAAKDLSRAEAEIELLQ 1047
Cdd:COG1196    730 LEA-EREELLEELLEEEELLEEEALEELPEPPDLEELERELERLE 773
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1321-2083 5.42e-22

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 104.37  E-value: 5.42e-22
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1321 RDLENEVSRLED--ITHHLKSKHQEERWLKTSRQHPEKEVEELHRNIDDLVQEKKELELEVEELHRTVERHQQRrdfidg 1398
Cdd:TIGR02168  216 KELKAELRELELalLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKE------ 289

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1399 nvenlmteleiekslkhHEDIVDEIECLEKTLLKRRSELREADRLLAEAESELACTKEKTKSAVEKFTDAKRNLLQTESD 1478
Cdd:TIGR02168  290 -----------------LYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEE 352

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1479 AEALEKRAQETALNLVKAEQQLRLLQADAEDLEQHKIKQEEILKEINKVVAAKDADFQCLNEKKEKLTEELQSLQRDIKA 1558
Cdd:TIGR02168  353 LESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEE 432

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1559 AEVNEDHhlQVLKESESLLQAKRAELETLKSQVTSQQQELAVLDSQLGHRREELLLLQDSLTQAKADLQEALTLGETEVA 1638
Cdd:TIGR02168  433 AELKELQ--AELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKA 510

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1639 EKCSHIR---EVKSLLEELSFQKG---ELNVHISERRTQLTLIKQEIEKE-------EENLEVVLQQLSKHKTELKNVAD 1705
Cdd:TIGR02168  511 LLKNQSGlsgILGVLSELISVDEGyeaAIEAALGGRLQAVVVENLNAAKKaiaflkqNELGRVTFLPLDSIKGTEIQGND 590

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1706 ILQLETNE-LQSLKLQHDQKVVELEKTQVDLLEGKLELESLQQTAQQQRRELERQR------------------------ 1760
Cdd:TIGR02168  591 REILKNIEgFLGVAKDLVKFDPKLRKALSYLLGGVLVVDDLDNALELAKKLRPGYRivtldgdlvrpggvitggsaktns 670

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1761 QLLERdRRETERVRAETQALQSCIECLNKEKEHLQEQCESWEKKSSHAKRVLAATEESNNTEQSKLGQLEVSVRKLQQEL 1840
Cdd:TIGR02168  671 SILER-RREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERI 749

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1841 ELLSQDKLALHSDSAQEQQQLQDKREALNSLQKELENTQDHLNLAKQDLMHTTKCQSALLSEQAQLQKDVSQWTARLESC 1920
Cdd:TIGR02168  750 AQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESL 829

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1921 QKETETKEQQLQELQDEIRESKLQLDQQEMVFQKLQKERESEEQKLvasiVSLEQQQGQLERELMDQKSKLEWLLTDVSA 2000
Cdd:TIGR02168  830 ERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESEL----EALLNERASLEEALALLRSELEELSEELRE 905

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 2001 AEGRLRTLQKE-ERCTESLEKM---LSQAKQQLSEREQQLMEKSGDLLALQKEadgmradfslLRNQFLTERKKAEKQVA 2076
Cdd:TIGR02168  906 LESKRSELRRElEELREKLAQLelrLEGLEVRIDNLQERLSEEYSLTLEEAEA----------LENKIEDDEEEARRRLK 975


                   ....*..
gi 1958764989 2077 GLKEALK 2083
Cdd:TIGR02168  976 RLENKIK 982
Drf_FH1 pfam06346
Formin Homology Region 1; This region is found in some of the Diaphanous related formins (Drfs) ...
 1238-1300 4.77e-06

Formin Homology Region 1; This region is found in some of the Diaphanous related formins (Drfs). It consists of low complexity repeats of around 12 residues.


:

Pssm-ID: 461881 [Multi-domain]  Cd Length: 157  Bit Score: 48.71  E-value: 4.77e-06
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1958764989 1238 PPFVPPPGYIMYTVLPDGSPVPqgvalyaPSPPLPHSSH----PLTPGTVVYGPPPA--GAPIIYGPPP 1300
Cdd:pfam06346    1 PPPPPLPGDSSTIPLPPGACIP-------TPPPLPGGGGppppPPLPGSAAIPPPPPlpGGTSIPPPPP 62
PTZ00108 super family cl36510
DNA topoisomerase 2-like protein; Provisional
 267-535 1.85e-04

DNA topoisomerase 2-like protein; Provisional


The actual alignment was detected with superfamily member PTZ00108:

Pssm-ID: 240271 [Multi-domain]  Cd Length: 1388  Bit Score: 46.96  E-value: 1.85e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  267 FSLEEIERLEKDLEKKTVETEELKNKQT---------KFLEEIKHQDK--LNKSLKEEAM----------LQKQSCEELE 325
Cdd:PTZ00108  1099 LTKEKVEKLNAELEKKEKELEKLKNTTPkdmwledldKFEEALEEQEEveEKEIAKEQRLksktkgkaskLRKPKLKKKE 1178

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  326 SDLNTKKELLKQKTVELTRACQKQYELEQELAFYKIDAKFEPLNYYPSEYAEMDKSPDESPYIGKSRYKRNMFATETYIV 405
Cdd:PTZ00108  1179 KKKKKSSADKSKKASVVGNSKRVDSDEKRKLDDKPDNKKSNSSGSDQEDDEEQKTKPKKSSVKRLKSKKNNSSKSSEDND 1258

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  406 SDAQAVQVRKMVPDGGQLRhEHAPRAQAPPDVQLEDTGKQIVAAQTRlselhhEIEAAEQKVLRATQEFKQLEE-----A 480
Cdd:PTZ00108  1259 EFSSDDLSKEGKPKNAPKR-VSAVQYSPPPPSKRPDGESNGGSKPSS------PTKKKVKKRLEGSLAALKKKKksekkT 1331

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1958764989  481 IRQKKISEAEKDLLLKQLSGRLRHLNKLRQEALDLEAQLEKQRKEIAEKHEEINS 535
Cdd:PTZ00108  1332 ARKKKSKTRVKQASASQSSRLLRRPRKKKSDSSSEDDDDSEVDDSEDEDDEDDED 1386
 
Name Accession Description Interval E-value
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 89-261 2.87e-26

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 109.11  E-value: 2.87e-26
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989   89 KKLTKQDNLALVKSL-------NlslskdggkKFRYIENLEKCVKLEVLNLSYNLIAKIEKVDKLLRLRELNLSYNKISK 161
Cdd:cd21340     12 KNITKIDNLSLCKNLkvlylydN---------KITKIENLEFLTNLTHLYLQNNQIEKIENLENLVNLKKLYLGGNRISV 82

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  162 IEGLENMCN------------------------------LQKLNLAGNEIEHIpgWFSKKLKSLRVLNLKGNKISSLQDV 211
Cdd:cd21340     83 VEGLENLTNleelhienqrlppgekltfdprslaalsnsLRVLNISGNNIDSL--EPLAPLRNLEQLDASNNQISDLEEL 160

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1958764989  212 SK-LKPLQDLTSLTLIDNPVVALPHYLQFIIFHLRSLESLEGQPVTTQDRQ 261
Cdd:cd21340    161 LDlLSSWPSLRELDLTGNPVCKKPKYRDKIILASKSLEVLDGKEITDTERQ 211
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 452-1047 3.68e-25

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 114.65  E-value: 3.68e-25
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  452 RLSELHHEIEAAEQ-KVLRATQEFKQLEEAIRQKKISEAEKDLLLKQLSGRLRHLNKLRQEALDLEAQLEKQRKEIAEKH 530
Cdd:COG1196    201 QLEPLERQAEKAERyRELKEELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELE 280

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  531 EEINSAQLATDLLdskdpkqshmKAQKRGKEQQLDIMNKQYTQLESRLDEILCRIATETEEIKDLEQQLTDGQIAANEAL 610
Cdd:COG1196    281 LELEEAQAEEYEL----------LAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAE 350

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  611 KKDLEgvisglqeylgtikgQAAQAQNECRKLQDEKETLLQRLTEVKQEKDELEIVAMDAENMRKELAELENALQEQHEV 690
Cdd:COG1196    351 EELEE---------------AEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLER 415

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  691 NASLQQAQGDLSAYETELETQLK-LKDAETSQLKQELENLVRRTQLEQSVLQTELEKERQSLRDALGKAQSSEEKQQENS 769
Cdd:COG1196    416 LERLEEELEELEEALAELEEEEEeEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLL 495

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  770 ELRAQLKQLQDDNSLLKKQLKDFQSHLNHVVDGLIHPEEVAARVDELRkrlkLGAGEMRIHSPSDVLGKSLADLQKQ--- 846
Cdd:COG1196    496 LLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAA----LAAALQNIVVEDDEVAAAAIEYLKAaka 571

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  847 ----FSEILARSQWEKEEAQVRERKLHEEMALQQEKLANGQEEFKQACERALEARIkfDKRQHNARIQQLENEIHYLQEN 922
Cdd:COG1196    572 gratFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTL--VAARLEAALRRAVTLAGRLREV 649

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  923 LKSMEKIQGLTDLQLQEADEEKERILAQLQELEKKKRREDARSQEQFLGLDTELKSLKKAVAASDKLAAAELTIAKEQLK 1002
Cdd:COG1196    650 TLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQ 729

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|....*
gi 1958764989 1003 SLHgTVMRINQERAEELQEAERSSREAMQAAKDLSRAEAEIELLQ 1047
Cdd:COG1196    730 LEA-EREELLEELLEEEELLEEEALEELPEPPDLEELERELERLE 773
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1321-2083 5.42e-22

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 104.37  E-value: 5.42e-22
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1321 RDLENEVSRLED--ITHHLKSKHQEERWLKTSRQHPEKEVEELHRNIDDLVQEKKELELEVEELHRTVERHQQRrdfidg 1398
Cdd:TIGR02168  216 KELKAELRELELalLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKE------ 289

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1399 nvenlmteleiekslkhHEDIVDEIECLEKTLLKRRSELREADRLLAEAESELACTKEKTKSAVEKFTDAKRNLLQTESD 1478
Cdd:TIGR02168  290 -----------------LYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEE 352

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1479 AEALEKRAQETALNLVKAEQQLRLLQADAEDLEQHKIKQEEILKEINKVVAAKDADFQCLNEKKEKLTEELQSLQRDIKA 1558
Cdd:TIGR02168  353 LESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEE 432

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1559 AEVNEDHhlQVLKESESLLQAKRAELETLKSQVTSQQQELAVLDSQLGHRREELLLLQDSLTQAKADLQEALTLGETEVA 1638
Cdd:TIGR02168  433 AELKELQ--AELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKA 510

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1639 EKCSHIR---EVKSLLEELSFQKG---ELNVHISERRTQLTLIKQEIEKE-------EENLEVVLQQLSKHKTELKNVAD 1705
Cdd:TIGR02168  511 LLKNQSGlsgILGVLSELISVDEGyeaAIEAALGGRLQAVVVENLNAAKKaiaflkqNELGRVTFLPLDSIKGTEIQGND 590

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1706 ILQLETNE-LQSLKLQHDQKVVELEKTQVDLLEGKLELESLQQTAQQQRRELERQR------------------------ 1760
Cdd:TIGR02168  591 REILKNIEgFLGVAKDLVKFDPKLRKALSYLLGGVLVVDDLDNALELAKKLRPGYRivtldgdlvrpggvitggsaktns 670

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1761 QLLERdRRETERVRAETQALQSCIECLNKEKEHLQEQCESWEKKSSHAKRVLAATEESNNTEQSKLGQLEVSVRKLQQEL 1840
Cdd:TIGR02168  671 SILER-RREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERI 749

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1841 ELLSQDKLALHSDSAQEQQQLQDKREALNSLQKELENTQDHLNLAKQDLMHTTKCQSALLSEQAQLQKDVSQWTARLESC 1920
Cdd:TIGR02168  750 AQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESL 829

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1921 QKETETKEQQLQELQDEIRESKLQLDQQEMVFQKLQKERESEEQKLvasiVSLEQQQGQLERELMDQKSKLEWLLTDVSA 2000
Cdd:TIGR02168  830 ERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESEL----EALLNERASLEEALALLRSELEELSEELRE 905

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 2001 AEGRLRTLQKE-ERCTESLEKM---LSQAKQQLSEREQQLMEKSGDLLALQKEadgmradfslLRNQFLTERKKAEKQVA 2076
Cdd:TIGR02168  906 LESKRSELRRElEELREKLAQLelrLEGLEVRIDNLQERLSEEYSLTLEEAEA----------LENKIEDDEEEARRRLK 975


                   ....*..
gi 1958764989 2077 GLKEALK 2083
Cdd:TIGR02168  976 RLENKIK 982
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
96-250 2.40e-19

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 93.07  E-value: 2.40e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989   96 NLALVKSLNLSlskdgGKKFRYI-ENLEKCVKLEVLNLSYNLIAKI-EKVDKLLRLRELNLSYNKISKI-EGLENMCNLQ 172
Cdd:COG4886    134 NLTNLKELDLS-----NNQLTDLpEPLGNLTNLKSLDLSNNQLTDLpEELGNLTNLKELDLSNNQITDLpEPLGNLTNLE 208

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1958764989  173 KLNLAGNEIEHIPGWFSkKLKSLRVLNLKGNKISSLQDVSKLKplqDLTSLTLIDNPVVALPHYLQfiifhLRSLESL 250
Cdd:COG4886    209 ELDLSGNQLTDLPEPLA-NLTNLETLDLSNNQLTDLPELGNLT---NLEELDLSNNQLTDLPPLAN-----LTNLKTL 277
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 438-1120 3.08e-19

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 95.51  E-value: 3.08e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  438 QLEDTGKQIVAAQTRLSELHHEIEAAEQKVLRATQEFKQLEEAI----RQKKISEAEKDLLLKQLSGRLRHLNKLRQEAL 513
Cdd:TIGR02168  254 ELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEIsrleQQKQILRERLANLERQLEELEAQLEELESKLD 333

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  514 DLEAQLEKQRKEIAEKHEEINSAQlatDLLDSKDPKQSHMKAQKRGKEQQLDIMNKQYTQLESRLDEILCRIATETEEIK 593
Cdd:TIGR02168  334 ELAEELAELEEKLEELKEELESLE---AELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLE 410

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  594 DLEQQLTDGQIAANEALKKDLEGVISGLQEYLGTIKGQAAQAQNECRKLQDEKETLLQRLTEVKQEKDELEIVAMDAENM 673
Cdd:TIGR02168  411 RLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQAR 490

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  674 RKELAELENALQEQHEVNASLQQAQGDLSAYE----TELETQLKLKDAETSQLKQELENLVRRTqLEQSVLQTELEKERQ 749
Cdd:TIGR02168  491 LDSLERLQENLEGFSEGVKALLKNQSGLSGILgvlsELISVDEGYEAAIEAALGGRLQAVVVEN-LNAAKKAIAFLKQNE 569

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  750 SLRDAL--GKAQSSEEKQQENSELRAQLKQLQDDNSLLKKQLKDFQSHLNHVVDGLIhpeeVAARVDELRKRLKLGAGEM 827
Cdd:TIGR02168  570 LGRVTFlpLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVL----VVDDLDNALELAKKLRPGY 645

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  828 RIHSPSDVL---------GKSLADLQKQFSEI-LARSQWEKEEAQVRERKLHEEMALQQEKLANGQEEFKQACERALEAR 897
Cdd:TIGR02168  646 RIVTLDGDLvrpggvitgGSAKTNSSILERRReIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELS 725

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  898 IKF-----DKRQHNARIQQLENEIHYLQENLKSMEKIQGLTDLQLQEADEEKERILAQLQELEKKKrredARSQEQFLGL 972
Cdd:TIGR02168  726 RQIsalrkDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQI----EQLKEELKAL 801

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  973 DTELKSLKKAVAASdKLAAAELTIAKEQLKSLHGTVMRINQERAEELQEAERSSREAMQAAKDLSRAEAEIEL-LQHLLR 1051
Cdd:TIGR02168  802 REALDELRAELTLL-NEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESeLEALLN 880

                          650       660       670       680       690       700       710
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1958764989 1052 EREGQF------RDEMENAHVGSKGANLQLLEIEALKEAMAKQRAEItrlrdVLNLTGTgkKGGIENVVEEIAEL 1120
Cdd:TIGR02168  881 ERASLEealallRSELEELSEELRELESKRSELRRELEELREKLAQL-----ELRLEGL--EVRIDNLQERLSEE 948
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1407-1940 3.66e-19

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 95.00  E-value: 3.66e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1407 LEIEKSLKHHEDIVDEIECLEKTLLKRRSELREADRLLAEAESELACTKEKTKSAVEKFTDAKRNLLQTESDAEALEKRA 1486
Cdd:COG1196    232 LKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERR 311

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1487 QETALNLVKAEQQLRLLQADAEDLEQHKIKQEEILKEINKVVAAKDADFQCLNEKKEKLTEELQSLQRDIKAAEVNEDHH 1566
Cdd:COG1196    312 RELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEA 391

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1567 LQVLKESESLLQAKRAELETLKSQVTSQQQELAVLDSQLGHRREELLLLQDSLTQAKADLQEALTLGETEVAEKCSHIRE 1646
Cdd:COG1196    392 LRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEE 471

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1647 VKSLLEELSFQKGELNVHISERRTQLTLIKQEIEKEE--ENLEVVLQQLSKHKTELKNVADILQLETNELQSLKLQHDQK 1724
Cdd:COG1196    472 AALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEgvKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNI 551

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1725 VVELEKTQVDLLE-------GKLELESLQQTAQQQRRELERQRQLLERDRRETERVRAETQALQSCIECLNKEKEHLQEQ 1797
Cdd:COG1196    552 VVEDDEVAAAAIEylkaakaGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAAR 631

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1798 CESWEKKSSH----AKRVLAATEESNNTEQSKLGQLEVSVRKLQQELELLSQDKLALHSDSAQEQQQLQDKREALNSLQK 1873
Cdd:COG1196    632 LEAALRRAVTlagrLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAE 711

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1958764989 1874 ELENTQDHLNLAKQDLMHTTKCQSALLSEQAQLQKDVSQWTARLESCQKETETKEQQLQELQDEIRE 1940
Cdd:COG1196    712 AEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEA 778
LRR_9 pfam14580
Leucine-rich repeat;
130-279 1.10e-14

Leucine-rich repeat;


Pssm-ID: 405295 [Multi-domain]  Cd Length: 175  Bit Score: 74.03  E-value: 1.10e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  130 LNLSYNLIAKIEKVDKLL-RLRELNLSYNKISKIEGLENMCNLQKLNLAGNEIEHIPGWFSKKLKSLRVLNLKGNKISSL 208
Cdd:pfam14580   24 LDLRGYKIPIIENLGATLdQFDTIDFSDNEIRKLDGFPLLRRLKTLLLNNNRICRIGEGLGEALPNLTELILTNNNLQEL 103

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1958764989  209 QDVSKLKPLQDLTSLTLIDNPVVALPHYLQFIIFHLRSLESLEGQPVTTQDRQEAFERFSLEEIERLEKDL 279
Cdd:pfam14580  104 GDLDPLASLKKLTFLSLLRNPVTNKPHYRLYVIYKVPQLRLLDFRKVKQKERQAAEKMFRSKQGKQLAKEI 174
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 431-1098 2.36e-14

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 79.50  E-value: 2.36e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  431 AQAPPDVQLEDTGKQIVAAQTRLSELHHEIEAAEQKVLRATQEFKQLEEAIRQKKISeaeKDLLLKQLSGRLRHLNKLRQ 510
Cdd:pfam12128  238 KIRPEFTKLQQEFNTLESAELRLSHLHFGYKSDETLIASRQEERQETSAELNQLLRT---LDDQWKEKRDELNGELSAAD 314

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  511 EALdleAQLEKQRKEIAEKH---EEINSAQLATDlLDSKDPKQSHMKAQKRGKEQQLDIMNKQYTQLESRLDEILCRIAT 587
Cdd:pfam12128  315 AAV---AKDRSELEALEDQHgafLDADIETAAAD-QEQLPSWQSELENLEERLKALTGKHQDVTAKYNRRRSKIKEQNNR 390

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  588 ETEEIKDLEQQLTDGQIAANEALKKDLEGVISGLQEylgtikgqaaQAQNECRKLQDEKETLLQRLTEVKQEKDELEIVA 667
Cdd:pfam12128  391 DIAGIKDKLAKIREARDRQLAVAEDDLQALESELRE----------QLEAGKLEFNEEEYRLKSRLGELKLRLNQATATP 460

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  668 MDAENMRKELAELENALQEQHEVNASLQQAQGDLSAYETELETQL-KLKDAE--TSQLKQELENLVRRTQLEQSVLQTEL 744
Cdd:pfam12128  461 ELLLQLENFDERIERAREEQEAANAEVERLQSELRQARKRRDQASeALRQASrrLEERQSALDELELQLFPQAGTLLHFL 540

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  745 EKERQSLRDALGKAQSSEEKQQENSELRAQLKQLQDDNSLLKKQLKdfqshlnhvVDGLIHPEEVAARvDELRKRLklga 824
Cdd:pfam12128  541 RKEAPDWEQSIGKVISPELLHRTDLDPEVWDGSVGGELNLYGVKLD---------LKRIDVPEWAASE-EELRERL---- 606

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  825 gemrihspsDVLGKSL---ADLQKQFSEILARSQWEKEEAQVRE---RKLHEEMALQQEKLANGQEEFKQACERALEARi 898
Cdd:pfam12128  607 ---------DKAEEALqsaREKQAAAEEQLVQANGELEKASREEtfaRTALKNARLDLRRLFDEKQSEKDKKNKALAER- 676

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  899 kfdKRQHNARIQQLENEIHYLQENLKSMEKIQgltDLQLQEADEEKeriLAQLQELEKKKRREDARSQEQFL----GLDT 974
Cdd:pfam12128  677 ---KDSANERLNSLEAQLKQLDKKHQAWLEEQ---KEQKREARTEK---QAYWQVVEGALDAQLALLKAAIAarrsGAKA 747

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  975 ELKSLKKAVAAS-DKLAAAELTIAK--EQLKSLHGTVMRINQERAEELQ----EAERSSREAMQAAKDLSRAEAEIELLQ 1047
Cdd:pfam12128  748 ELKALETWYKRDlASLGVDPDVIAKlkREIRTLERKIERIAVRRQEVLRyfdwYQETWLQRRPRLATQLSNIERAISELQ 827

                          650       660       670       680       690
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1958764989 1048 HLLREREGQFRDEMENAHVGSKGANLQLLEieaLKEAMAKQRAEITRLRDV 1098
Cdd:pfam12128  828 QQLARLIADTKLRRAKLEMERKASEKQQVR---LSENLRGLRCEMSKLATL 875
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1330-2110 5.17e-14

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 78.24  E-value: 5.17e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1330 LEDITHHLKSKhqeERWLKTSRQHPEKEVEELHRNIDDLVQEKKELELEVEELHRTVERHQQRRDFIDGNVENLMTELEI 1409
Cdd:pfam15921   80 LEEYSHQVKDL---QRRLNESNELHEKQKFYLRQSVIDLQTKLQEMQMERDAMADIRRRESQSQEDLRNQLQNTVHELEA 156

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1410 EKSLKHH--EDIVDEIECLEKTLLKRRSELREADRLLAEaeselactkektksavekFTDAKRNLLQTESDAEALEKRAQ 1487
Cdd:pfam15921  157 AKCLKEDmlEDSNTQIEQLRKMMLSHEGVLQEIRSILVD------------------FEEASGKKIYEHDSMSTMHFRSL 218

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1488 ETALNLVkaeqqLRLLQADAEDLEQHKIKQEEILKEINkvvaakdadfqclNEKKEKLTEELQSLQRDIKaaevnedhhl 1567
Cdd:pfam15921  219 GSAISKI-----LRELDTEISYLKGRIFPVEDQLEALK-------------SESQNKIELLLQQHQDRIE---------- 270

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1568 QVLKESESLLQAKRAELETLKSQVTSQQQELAVLDSQLGHRRE----ELLLLQDSLTQAKADLQEALTLGETEVaekcsh 1643
Cdd:pfam15921  271 QLISEHEVEITGLTEKASSARSQANSIQSQLEIIQEQARNQNSmymrQLSDLESTVSQLRSELREAKRMYEDKI------ 344

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1644 irevksllEELSFQKGELNVHISERRTQLTLIKQEIEKEEENLEVVLQQLSKHKTELKnvadiLQLETNEL-------QS 1716
Cdd:pfam15921  345 --------EELEKQLVLANSELTEARTERDQFSQESGNLDDQLQKLLADLHKREKELS-----LEKEQNKRlwdrdtgNS 411

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1717 LKLQHDQKVVELEKTQVDLLEGKleLESLQQTAQQQrreLERQRQLLERDRRETERVRAETQALQSCIECLNKEKEHLQE 1796
Cdd:pfam15921  412 ITIDHLRRELDDRNMEVQRLEAL--LKAMKSECQGQ---MERQMAAIQGKNESLEKVSSLTAQLESTKEMLRKVVEELTA 486

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1797 Q---CESWEKKSSHAKRVLAATEESNNTEQSKLGQLEVSVRKLQQELELLSQDKLALHSDSAQEQQ---QLQDKREALNS 1870
Cdd:pfam15921  487 KkmtLESSERTVSDLTASLQEKERAIEATNAEITKLRSRVDLKLQELQHLKNEGDHLRNVQTECEAlklQMAEKDKVIEI 566

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1871 LQKELENTQdhlnlakQDLMHTTKCQSALLSEQAQLQKDVSQWTARLESCQKETETKEQQLQELqdEIRESKLQLDQQEM 1950
Cdd:pfam15921  567 LRQQIENMT-------QLVGQHGRTAGAMQVEKAQLEKEINDRRLELQEFKILKDKKDAKIREL--EARVSDLELEKVKL 637

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1951 VFQKLQKEReseeqklvaSIVSLEQQQGQLERELMDQKSKLEWLLTDVSAAEGRLRTLQKE-ERCTESLEKMLSQAKQQL 2029
Cdd:pfam15921  638 VNAGSERLR---------AVKDIKQERDQLLNEVKTSRNELNSLSEDYEVLKRNFRNKSEEmETTTNKLKMQLKSAQSEL 708

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 2030 SEREQQLMEKSGDLLALQKEADGMRADFSLLRNQFlterKKAEKQVAGLKEALkiQRSQLEKNLLeqKQENSCMQKEMAT 2109
Cdd:pfam15921  709 EQTRNTLKSMEGSDGHAMKVAMGMQKQITAKRGQI----DALQSKIQFLEEAM--TNANKEKHFL--KEEKNKLSQELST 780


                   .
gi 1958764989 2110 I 2110
Cdd:pfam15921  781 V 781
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 840-1662 8.93e-13

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 74.32  E-value: 8.93e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  840 LADLQKQFSEILARSQWEKEEAQVRERKLHEEMALQQEKLANGQEEFKQACERALEARIKFDkrQHNARIQQLENEIHYL 919
Cdd:TIGR02168  230 LVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELY--ALANEISRLEQQKQIL 307

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  920 QENLKSMEKIQGLTDLQLQEADEEKERILAQLQELEKK-----------------KRREDARSQEQFLGLDTELKSLKKA 982
Cdd:TIGR02168  308 RERLANLERQLEELEAQLEELESKLDELAEELAELEEKleelkeelesleaeleeLEAELEELESRLEELEEQLETLRSK 387

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  983 VAA---SDKLAAAELTIAKEQLKSLHGTVMRINQERAEELQEAERSSREAMQAakDLSRAEAEIELLQHLLREREGQFRD 1059
Cdd:TIGR02168  388 VAQlelQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQA--ELEELEEELEELQEELERLEEALEE 465

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1060 EMEnahvgskganlqllEIEALKEAMAKQRAEITRLRDVLNLTGTGkKGGIENVVEEIAELRHAVSAQNEYISSMADPVQ 1139
Cdd:TIGR02168  466 LRE--------------ELEEAEQALDAAERELAQLQARLDSLERL-QENLEGFSEGVKALLKNQSGLSGILGVLSELIS 530

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1140 RQGCWyfmppppsskvsshssQATKDSGLGLKCTASTPLRSQQAGQ------QEEKGSSGPLPASgywvyspIRSTPHKS 1213
Cdd:TIGR02168  531 VDEGY----------------EAAIEAALGGRLQAVVVENLNAAKKaiaflkQNELGRVTFLPLD-------SIKGTEIQ 587

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1214 FSKREDADNGGDSQEESGLDDQEDPPFVPPPGYIMYTVLpdgsPVPQGVALYAPSPPLPHSSHPLTP-GTVVYgpppAGA 1292
Cdd:TIGR02168  588 GNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVL----VVDDLDNALELAKKLRPGYRIVTLdGDLVR----PGG 659

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1293 PIIYGPPPANfavplisMGVQHCNIpEHRDLENEVSRLEDITHHLKSKHQEerwLKTSRQHPEKEVEELHRNIDDLVQEK 1372
Cdd:TIGR02168  660 VITGGSAKTN-------SSILERRR-EIEELEEKIEELEEKIAELEKALAE---LRKELEELEEELEQLRKELEELSRQI 728

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1373 KELELEVEELHRTVERHQQRRDFIDGNVENLMTELE-----IEKSLKHHEDIVDEIECLEKTLLKRRSELREADRLLAEA 1447
Cdd:TIGR02168  729 SALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEeleerLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDEL 808

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1448 ESELACTKektksavEKFTDAKRNLLQTESDAEALEKRAQETALNLVKAEQQLRLLQADAEDLEQHKIKQEEILKEINKV 1527
Cdd:TIGR02168  809 RAELTLLN-------EEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNE 881

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1528 VAAKDADFQCLNEKKEKLTEELQSLQRDIKAAEVNEDHHLQVLKESESLLQAKRAELETLKSQVTSQQQ-ELAVLDSQLG 1606
Cdd:TIGR02168  882 RASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSlTLEEAEALEN 961

                          810       820       830       840       850
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1958764989 1607 HRREELLLLQDSLTQAKADLQEALTLGETEVAEkcshIREVKSLLEELSFQKGELN 1662
Cdd:TIGR02168  962 KIEDDEEEARRRLKRLENKIKELGPVNLAAIEE----YEELKERYDFLTAQKEDLT 1013
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1323-1804 2.76e-11

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 68.94  E-value: 2.76e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1323 LENEVSRLEDITHHLKSKHQEERWLKTSRQHPEKEVEELHRNIDDLVQEKKELELEVEELHRTVERHQQRRDFIDGNVEN 1402
Cdd:PRK03918   195 IKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEELKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKE 274

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1403 LMTELEIEKSLKHHEDIVDEIECLEKTLLKRRSELREADRLLAEAESELACTKEKTKSAVEK----------FTDAKRNL 1472
Cdd:PRK03918   275 IEELEEKVKELKELKEKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEERIKELEEKeerleelkkkLKELEKRL 354

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1473 LQTESDAEALEK-RAQETALNLVKAEQQLRLLQADAEDLEQHKIKQEEILKEINKVVAAKDADFQCLNEKKEKLtEELQS 1551
Cdd:PRK03918   355 EELEERHELYEEaKAKKEELERLKKRLTGLTPEKLEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAI-EELKK 433

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1552 LQRD--IKAAEVNEDHHLQVLKESESLLQAKRAELETLKSQVTSQQQELAVLDSQLGHRREELLLLQD------------ 1617
Cdd:PRK03918   434 AKGKcpVCGRELTEEHRKELLEEYTAELKRIEKELKEIEEKERKLRKELRELEKVLKKESELIKLKELaeqlkeleeklk 513

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1618 --SLTQAKADLQEALTLGE---------TEVAEKCSHIREVKSLLEELSFQKGELNVHISERRTQLTLIKQEIEKEEENL 1686
Cdd:PRK03918   514 kyNLEELEKKAEEYEKLKEkliklkgeiKSLKKELEKLEELKKKLAELEKKLDELEEELAELLKELEELGFESVEELEER 593

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1687 EVVLQQLSKHKTELKNVADILQLETNELQSLKLQHDQKVVELEKTQVDLLEGKLELESLQQTAQQQrrELERQRQLLERD 1766
Cdd:PRK03918   594 LKELEPFYNEYLELKDAEKELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEELEKKYSEE--EYEELREEYLEL 671

                          490       500       510
                   ....*....|....*....|....*....|....*...
gi 1958764989 1767 RRETERVRAETQALQSCIECLNKEKEHLQEQCESWEKK 1804
Cdd:PRK03918   672 SRELAGLRAELEELEKRREEIKKTLEKLKEELEEREKA 709
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
509-1121 4.37e-10

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 65.06  E-value: 4.37e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  509 RQEAL-DLEAQLEkqRKEIAEKHEEINSAQLAtdlLDSKDPKQSHMKAQKRGKEQQLDimnkqytqlesRLDEILCRIAT 587
Cdd:PRK02224   185 QRGSLdQLKAQIE--EKEEKDLHERLNGLESE---LAELDEEIERYEEQREQARETRD-----------EADEVLEEHEE 248

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  588 ETEEIKDLEQQLTDGQ--IAANEALKKDLEGVISGLQEYLGTIKGQAAQAQNECRKLQDEKETLLQRLTEVKQEKDELei 665
Cdd:PRK02224   249 RREELETLEAEIEDLRetIAETEREREELAEEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEEL-- 326

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  666 vamdaenmRKELAELENALQEQHEVNASLQQAQGDLSAYETELETQLKLKDAETSQLKQELENlvRRTQLEqsvlqtELE 745
Cdd:PRK02224   327 --------RDRLEECRVAAQAHNEEAESLREDADDLEERAEELREEAAELESELEEAREAVED--RREEIE------ELE 390

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  746 KERQSLRDALGKAQSSEEKQQENSELraqlkqLQDDNSLLKKQLKDFQSHLnhvvdglihpEEVAARVDELRKRLKLGag 825
Cdd:PRK02224   391 EEIEELRERFGDAPVDLGNAEDFLEE------LREERDELREREAELEATL----------RTARERVEEAEALLEAG-- 452

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  826 emriHSPSdvLGKSLADlqkqfSEILARSQWEKEEAQVRERKLhEEMALQQEKLANGQEEFKQACERALEARIKFDKRQH 905
Cdd:PRK02224   453 ----KCPE--CGQPVEG-----SPHVETIEEDRERVEELEAEL-EDLEEEVEEVEERLERAEDLVEAEDRIERLEERRED 520

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  906 -NARIQQLENEIHYLQENLKSMEKiqgltDLQLQEADEEKERILAQLQELEKKKRREDARSQEQFLG-LDTELKSLKKAV 983
Cdd:PRK02224   521 lEELIAERRETIEEKRERAEELRE-----RAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLAeLKERIESLERIR 595

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  984 AASDKLAAAEltiakEQLKSLhgtvmrinQERAEELQEAERSSREAMQAakdlsraeaeiellqhlLREREGQFRDEMEN 1063
Cdd:PRK02224   596 TLLAAIADAE-----DEIERL--------REKREALAELNDERRERLAE-----------------KRERKRELEAEFDE 645

                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1064 AHVGSKGANLQLLE--IEALKEAMAKQRAEITRLRDvlnltgtgKKGGIENVVEEIAELR 1121
Cdd:PRK02224   646 ARIEEAREDKERAEeyLEQVEEKLDELREERDDLQA--------EIGAVENELEELEELR 697
Drf_FH1 pfam06346
Formin Homology Region 1; This region is found in some of the Diaphanous related formins (Drfs) ...
 1238-1300 4.77e-06

Formin Homology Region 1; This region is found in some of the Diaphanous related formins (Drfs). It consists of low complexity repeats of around 12 residues.


Pssm-ID: 461881 [Multi-domain]  Cd Length: 157  Bit Score: 48.71  E-value: 4.77e-06
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1958764989 1238 PPFVPPPGYIMYTVLPDGSPVPqgvalyaPSPPLPHSSH----PLTPGTVVYGPPPA--GAPIIYGPPP 1300
Cdd:pfam06346    1 PPPPPLPGDSSTIPLPPGACIP-------TPPPLPGGGGppppPPLPGSAAIPPPPPlpGGTSIPPPPP 62
PTZ00108 PTZ00108
DNA topoisomerase 2-like protein; Provisional
 267-535 1.85e-04

DNA topoisomerase 2-like protein; Provisional


Pssm-ID: 240271 [Multi-domain]  Cd Length: 1388  Bit Score: 46.96  E-value: 1.85e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  267 FSLEEIERLEKDLEKKTVETEELKNKQT---------KFLEEIKHQDK--LNKSLKEEAM----------LQKQSCEELE 325
Cdd:PTZ00108  1099 LTKEKVEKLNAELEKKEKELEKLKNTTPkdmwledldKFEEALEEQEEveEKEIAKEQRLksktkgkaskLRKPKLKKKE 1178

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  326 SDLNTKKELLKQKTVELTRACQKQYELEQELAFYKIDAKFEPLNYYPSEYAEMDKSPDESPYIGKSRYKRNMFATETYIV 405
Cdd:PTZ00108  1179 KKKKKSSADKSKKASVVGNSKRVDSDEKRKLDDKPDNKKSNSSGSDQEDDEEQKTKPKKSSVKRLKSKKNNSSKSSEDND 1258

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  406 SDAQAVQVRKMVPDGGQLRhEHAPRAQAPPDVQLEDTGKQIVAAQTRlselhhEIEAAEQKVLRATQEFKQLEE-----A 480
Cdd:PTZ00108  1259 EFSSDDLSKEGKPKNAPKR-VSAVQYSPPPPSKRPDGESNGGSKPSS------PTKKKVKKRLEGSLAALKKKKksekkT 1331

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1958764989  481 IRQKKISEAEKDLLLKQLSGRLRHLNKLRQEALDLEAQLEKQRKEIAEKHEEINS 535
Cdd:PTZ00108  1332 ARKKKSKTRVKQASASQSSRLLRRPRKKKSDSSSEDDDDSEVDDSEDEDDEDDED 1386
PspC_subgroup_1 NF033838
pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, ...
 606-968 4.65e-03

pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A. The other form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site.


Pssm-ID: 468201 [Multi-domain]  Cd Length: 684  Bit Score: 41.92  E-value: 4.65e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  606 ANEALKKDLEGVISGLQEYLGTI-----KGQAAQAQNECRKLQDEKETLLQRLTEVKqEKDELEIVA-----MDA--ENM 673
Cdd:NF033838    52 GNESQKEHAKEVESHLEKILSEIqksldKRKHTQNVALNKKLSDIKTEYLYELNVLK-EKSEAELTSktkkeLDAafEQF 130

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  674 RKELAELENALQE-QHEVNASLQQAQG----DLSAYET------EL---ETQLKLKDAETSQLKQElenlVRRTQLEQSV 739
Cdd:NF033838   131 KKDTLEPGKKVAEaTKKVEEAEKKAKDqkeeDRRNYPTntyktlELeiaESDVEVKKAELELVKEE----AKEPRDEEKI 206

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  740 LQTELEKE-RQSLRDALGKAQSSEEKQQENSELRA--QLKQLQDDNSLLKKQLKDfQSHLNHVVDGlihpeeVAARVDEL 816
Cdd:NF033838   207 KQAKAKVEsKKAEATRLEKIKTDREKAEEEAKRRAdaKLKEAVEKNVATSEQDKP-KRRAKRGVLG------EPATPDKK 279

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  817 RKRLKLGA---GEMRIHSPSDVLGKSLADLQKQFSEILARSQWEKEE-----AQVRERKLHEEMALQQEKLANGQEEFKQ 888
Cdd:NF033838   280 ENDAKSSDssvGEETLPSPSLKPEKKVAEAEKKVEEAKKKAKDQKEEdrrnyPTNTYKTLELEIAESDVKVKEAELELVK 359

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  889 acERALEARIKFDKRQHNARIQQLENEIHYLqenlksmEKIQglTDlqLQEADEEKERILAqlqelEKKKRREDARSQEQ 968
Cdd:NF033838   360 --EEAKEPRNEEKIKQAKAKVESKKAEATRL-------EKIK--TD--RKKAEEEAKRKAA-----EEDKVKEKPAEQPQ 421
 
Name Accession Description Interval E-value
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 89-261 2.87e-26

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 109.11  E-value: 2.87e-26
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989   89 KKLTKQDNLALVKSL-------NlslskdggkKFRYIENLEKCVKLEVLNLSYNLIAKIEKVDKLLRLRELNLSYNKISK 161
Cdd:cd21340     12 KNITKIDNLSLCKNLkvlylydN---------KITKIENLEFLTNLTHLYLQNNQIEKIENLENLVNLKKLYLGGNRISV 82

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  162 IEGLENMCN------------------------------LQKLNLAGNEIEHIpgWFSKKLKSLRVLNLKGNKISSLQDV 211
Cdd:cd21340     83 VEGLENLTNleelhienqrlppgekltfdprslaalsnsLRVLNISGNNIDSL--EPLAPLRNLEQLDASNNQISDLEEL 160

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1958764989  212 SK-LKPLQDLTSLTLIDNPVVALPHYLQFIIFHLRSLESLEGQPVTTQDRQ 261
Cdd:cd21340    161 LDlLSSWPSLRELDLTGNPVCKKPKYRDKIILASKSLEVLDGKEITDTERQ 211
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 452-1047 3.68e-25

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 114.65  E-value: 3.68e-25
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  452 RLSELHHEIEAAEQ-KVLRATQEFKQLEEAIRQKKISEAEKDLLLKQLSGRLRHLNKLRQEALDLEAQLEKQRKEIAEKH 530
Cdd:COG1196    201 QLEPLERQAEKAERyRELKEELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELE 280

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  531 EEINSAQLATDLLdskdpkqshmKAQKRGKEQQLDIMNKQYTQLESRLDEILCRIATETEEIKDLEQQLTDGQIAANEAL 610
Cdd:COG1196    281 LELEEAQAEEYEL----------LAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAE 350

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  611 KKDLEgvisglqeylgtikgQAAQAQNECRKLQDEKETLLQRLTEVKQEKDELEIVAMDAENMRKELAELENALQEQHEV 690
Cdd:COG1196    351 EELEE---------------AEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLER 415

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  691 NASLQQAQGDLSAYETELETQLK-LKDAETSQLKQELENLVRRTQLEQSVLQTELEKERQSLRDALGKAQSSEEKQQENS 769
Cdd:COG1196    416 LERLEEELEELEEALAELEEEEEeEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLL 495

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  770 ELRAQLKQLQDDNSLLKKQLKDFQSHLNHVVDGLIHPEEVAARVDELRkrlkLGAGEMRIHSPSDVLGKSLADLQKQ--- 846
Cdd:COG1196    496 LLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAA----LAAALQNIVVEDDEVAAAAIEYLKAaka 571

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  847 ----FSEILARSQWEKEEAQVRERKLHEEMALQQEKLANGQEEFKQACERALEARIkfDKRQHNARIQQLENEIHYLQEN 922
Cdd:COG1196    572 gratFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTL--VAARLEAALRRAVTLAGRLREV 649

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  923 LKSMEKIQGLTDLQLQEADEEKERILAQLQELEKKKRREDARSQEQFLGLDTELKSLKKAVAASDKLAAAELTIAKEQLK 1002
Cdd:COG1196    650 TLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQ 729

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|....*
gi 1958764989 1003 SLHgTVMRINQERAEELQEAERSSREAMQAAKDLSRAEAEIELLQ 1047
Cdd:COG1196    730 LEA-EREELLEELLEEEELLEEEALEELPEPPDLEELERELERLE 773
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1321-2083 5.42e-22

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 104.37  E-value: 5.42e-22
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1321 RDLENEVSRLED--ITHHLKSKHQEERWLKTSRQHPEKEVEELHRNIDDLVQEKKELELEVEELHRTVERHQQRrdfidg 1398
Cdd:TIGR02168  216 KELKAELRELELalLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKE------ 289

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1399 nvenlmteleiekslkhHEDIVDEIECLEKTLLKRRSELREADRLLAEAESELACTKEKTKSAVEKFTDAKRNLLQTESD 1478
Cdd:TIGR02168  290 -----------------LYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEE 352

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1479 AEALEKRAQETALNLVKAEQQLRLLQADAEDLEQHKIKQEEILKEINKVVAAKDADFQCLNEKKEKLTEELQSLQRDIKA 1558
Cdd:TIGR02168  353 LESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEE 432

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1559 AEVNEDHhlQVLKESESLLQAKRAELETLKSQVTSQQQELAVLDSQLGHRREELLLLQDSLTQAKADLQEALTLGETEVA 1638
Cdd:TIGR02168  433 AELKELQ--AELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKA 510

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1639 EKCSHIR---EVKSLLEELSFQKG---ELNVHISERRTQLTLIKQEIEKE-------EENLEVVLQQLSKHKTELKNVAD 1705
Cdd:TIGR02168  511 LLKNQSGlsgILGVLSELISVDEGyeaAIEAALGGRLQAVVVENLNAAKKaiaflkqNELGRVTFLPLDSIKGTEIQGND 590

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1706 ILQLETNE-LQSLKLQHDQKVVELEKTQVDLLEGKLELESLQQTAQQQRRELERQR------------------------ 1760
Cdd:TIGR02168  591 REILKNIEgFLGVAKDLVKFDPKLRKALSYLLGGVLVVDDLDNALELAKKLRPGYRivtldgdlvrpggvitggsaktns 670

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1761 QLLERdRRETERVRAETQALQSCIECLNKEKEHLQEQCESWEKKSSHAKRVLAATEESNNTEQSKLGQLEVSVRKLQQEL 1840
Cdd:TIGR02168  671 SILER-RREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERI 749

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1841 ELLSQDKLALHSDSAQEQQQLQDKREALNSLQKELENTQDHLNLAKQDLMHTTKCQSALLSEQAQLQKDVSQWTARLESC 1920
Cdd:TIGR02168  750 AQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESL 829

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1921 QKETETKEQQLQELQDEIRESKLQLDQQEMVFQKLQKERESEEQKLvasiVSLEQQQGQLERELMDQKSKLEWLLTDVSA 2000
Cdd:TIGR02168  830 ERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESEL----EALLNERASLEEALALLRSELEELSEELRE 905

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 2001 AEGRLRTLQKE-ERCTESLEKM---LSQAKQQLSEREQQLMEKSGDLLALQKEadgmradfslLRNQFLTERKKAEKQVA 2076
Cdd:TIGR02168  906 LESKRSELRRElEELREKLAQLelrLEGLEVRIDNLQERLSEEYSLTLEEAEA----------LENKIEDDEEEARRRLK 975


                   ....*..
gi 1958764989 2077 GLKEALK 2083
Cdd:TIGR02168  976 RLENKIK 982
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1396-2139 8.00e-22

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 103.98  E-value: 8.00e-22
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1396 IDGNVENLmtELEIEKSLKHHEdIVDEIECLEKTLLKRRselreadrlLAEAESELACTKEKTKSAVEKFTDAKRNLLQT 1475
Cdd:TIGR02168  198 LERQLKSL--ERQAEKAERYKE-LKAELRELELALLVLR---------LEELREELEELQEELKEAEEELEELTAELQEL 265

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1476 ESDAEALEKRAQETALNLVKAEQQLRLLQADAEDLEQHKIKQEEILKEINKVVAAKDADFQ-------CLNEKKEKLTEE 1548
Cdd:TIGR02168  266 EEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEeleskldELAEELAELEEK 345

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1549 LQSLQRDIKAAEVNEDHHLQVLKESESLLQAKRAELETLKSQVTSQQQELAVLDSQLGHRREELLLLQDSLTQAKADLQE 1628
Cdd:TIGR02168  346 LEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEE 425

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1629 ALT-LGETEVAEKCSHIREVKSLLEELSFQKGELNVHISERRTQLTLIKQEIEKEEENLEVVLQQLSKHKTELKNVADIL 1707
Cdd:TIGR02168  426 LLKkLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFS 505

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1708 QLETNELQSLKLQHDQKVVELEKTQVDL-LEGKLEL---ESLQQ----TAQQQRRELERQRQLLERDRRETERVRAETQA 1779
Cdd:TIGR02168  506 EGVKALLKNQSGLSGILGVLSELISVDEgYEAAIEAalgGRLQAvvveNLNAAKKAIAFLKQNELGRVTFLPLDSIKGTE 585

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1780 LQSCIECLNKEKEHLQEQCESWEKKSSHAKRVLA------ATEESNNTEQSKLGQLEVSVRKLQQELELLSQDKLALHSD 1853
Cdd:TIGR02168  586 IQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSyllggvLVVDDLDNALELAKKLRPGYRIVTLDGDLVRPGGVITGGS 665

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1854 SAQEQQQLQDKREaLNSLQKELENTQDHLNLAKQDLMHTTKCQSALLSEQAQLQKDVSQWTARLESCQKETETKEQQLQE 1933
Cdd:TIGR02168  666 AKTNSSILERRRE-IEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQ 744

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1934 LQDEIRESKLQLDQQEMVFQKLQKERESEEQKLVASIVSLEQQQGQLEReLMDQKSKLEWLLTDVSAAEGRLR-TLQKEE 2012
Cdd:TIGR02168  745 LEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQ-LKEELKALREALDELRAELTLLNeEAANLR 823

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 2013 RCTESLEKMLSQAKQQLSEREQQLMEKSGDLLALQKEadgmRADFSLLRNQFLTERKKAEKQVAGLKEALKIQRSQLEKn 2092
Cdd:TIGR02168  824 ERLESLERRIAATERRLEDLEEQIEELSEDIESLAAE----IEELEELIEELESELEALLNERASLEEALALLRSELEE- 898

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|....*..
gi 1958764989 2093 lleqkqenscMQKEMATIELVAQDNHERARRLMKELRQMQQEYLELK 2139
Cdd:TIGR02168  899 ----------LSEELRELESKRSELRRELEELREKLAQLELRLEGLE 935
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
96-250 2.40e-19

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 93.07  E-value: 2.40e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989   96 NLALVKSLNLSlskdgGKKFRYI-ENLEKCVKLEVLNLSYNLIAKI-EKVDKLLRLRELNLSYNKISKI-EGLENMCNLQ 172
Cdd:COG4886    134 NLTNLKELDLS-----NNQLTDLpEPLGNLTNLKSLDLSNNQLTDLpEELGNLTNLKELDLSNNQITDLpEPLGNLTNLE 208

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1958764989  173 KLNLAGNEIEHIPGWFSkKLKSLRVLNLKGNKISSLQDVSKLKplqDLTSLTLIDNPVVALPHYLQfiifhLRSLESL 250
Cdd:COG4886    209 ELDLSGNQLTDLPEPLA-NLTNLETLDLSNNQLTDLPELGNLT---NLEELDLSNNQLTDLPPLAN-----LTNLKTL 277
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 438-1120 3.08e-19

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 95.51  E-value: 3.08e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  438 QLEDTGKQIVAAQTRLSELHHEIEAAEQKVLRATQEFKQLEEAI----RQKKISEAEKDLLLKQLSGRLRHLNKLRQEAL 513
Cdd:TIGR02168  254 ELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEIsrleQQKQILRERLANLERQLEELEAQLEELESKLD 333

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  514 DLEAQLEKQRKEIAEKHEEINSAQlatDLLDSKDPKQSHMKAQKRGKEQQLDIMNKQYTQLESRLDEILCRIATETEEIK 593
Cdd:TIGR02168  334 ELAEELAELEEKLEELKEELESLE---AELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLE 410

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  594 DLEQQLTDGQIAANEALKKDLEGVISGLQEYLGTIKGQAAQAQNECRKLQDEKETLLQRLTEVKQEKDELEIVAMDAENM 673
Cdd:TIGR02168  411 RLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQAR 490

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  674 RKELAELENALQEQHEVNASLQQAQGDLSAYE----TELETQLKLKDAETSQLKQELENLVRRTqLEQSVLQTELEKERQ 749
Cdd:TIGR02168  491 LDSLERLQENLEGFSEGVKALLKNQSGLSGILgvlsELISVDEGYEAAIEAALGGRLQAVVVEN-LNAAKKAIAFLKQNE 569

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  750 SLRDAL--GKAQSSEEKQQENSELRAQLKQLQDDNSLLKKQLKDFQSHLNHVVDGLIhpeeVAARVDELRKRLKLGAGEM 827
Cdd:TIGR02168  570 LGRVTFlpLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVL----VVDDLDNALELAKKLRPGY 645

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  828 RIHSPSDVL---------GKSLADLQKQFSEI-LARSQWEKEEAQVRERKLHEEMALQQEKLANGQEEFKQACERALEAR 897
Cdd:TIGR02168  646 RIVTLDGDLvrpggvitgGSAKTNSSILERRReIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELS 725

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  898 IKF-----DKRQHNARIQQLENEIHYLQENLKSMEKIQGLTDLQLQEADEEKERILAQLQELEKKKrredARSQEQFLGL 972
Cdd:TIGR02168  726 RQIsalrkDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQI----EQLKEELKAL 801

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  973 DTELKSLKKAVAASdKLAAAELTIAKEQLKSLHGTVMRINQERAEELQEAERSSREAMQAAKDLSRAEAEIEL-LQHLLR 1051
Cdd:TIGR02168  802 REALDELRAELTLL-NEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESeLEALLN 880

                          650       660       670       680       690       700       710
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1958764989 1052 EREGQF------RDEMENAHVGSKGANLQLLEIEALKEAMAKQRAEItrlrdVLNLTGTgkKGGIENVVEEIAEL 1120
Cdd:TIGR02168  881 ERASLEealallRSELEELSEELRELESKRSELRRELEELREKLAQL-----ELRLEGL--EVRIDNLQERLSEE 948
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1407-1940 3.66e-19

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 95.00  E-value: 3.66e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1407 LEIEKSLKHHEDIVDEIECLEKTLLKRRSELREADRLLAEAESELACTKEKTKSAVEKFTDAKRNLLQTESDAEALEKRA 1486
Cdd:COG1196    232 LKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERR 311

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1487 QETALNLVKAEQQLRLLQADAEDLEQHKIKQEEILKEINKVVAAKDADFQCLNEKKEKLTEELQSLQRDIKAAEVNEDHH 1566
Cdd:COG1196    312 RELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEA 391

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1567 LQVLKESESLLQAKRAELETLKSQVTSQQQELAVLDSQLGHRREELLLLQDSLTQAKADLQEALTLGETEVAEKCSHIRE 1646
Cdd:COG1196    392 LRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEE 471

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1647 VKSLLEELSFQKGELNVHISERRTQLTLIKQEIEKEE--ENLEVVLQQLSKHKTELKNVADILQLETNELQSLKLQHDQK 1724
Cdd:COG1196    472 AALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEgvKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNI 551

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1725 VVELEKTQVDLLE-------GKLELESLQQTAQQQRRELERQRQLLERDRRETERVRAETQALQSCIECLNKEKEHLQEQ 1797
Cdd:COG1196    552 VVEDDEVAAAAIEylkaakaGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAAR 631

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1798 CESWEKKSSH----AKRVLAATEESNNTEQSKLGQLEVSVRKLQQELELLSQDKLALHSDSAQEQQQLQDKREALNSLQK 1873
Cdd:COG1196    632 LEAALRRAVTlagrLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAE 711

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1958764989 1874 ELENTQDHLNLAKQDLMHTTKCQSALLSEQAQLQKDVSQWTARLESCQKETETKEQQLQELQDEIRE 1940
Cdd:COG1196    712 AEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEA 778
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
82-250 4.91e-18

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 89.22  E-value: 4.91e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989   82 YITEALIKKLTKQDNLALVKSLNLSLSKDGGKKFRYIENLEKCVKLEVLNLSYNLIAKI-EKVDKLLRLRELNLSYNKIS 160
Cdd:COG4886     70 SLLLLLLLSLLLLSLLLLGLTDLGDLTNLTELDLSGNEELSNLTNLESLDLSGNQLTDLpEELANLTNLKELDLSNNQLT 149

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  161 KI-EGLENMCNLQKLNLAGNEIEHIPGWFSkKLKSLRVLNLKGNKISSLQDVskLKPLQDLTSLTLIDNPVVALPHYLQf 239
Cdd:COG4886    150 DLpEPLGNLTNLKSLDLSNNQLTDLPEELG-NLTNLKELDLSNNQITDLPEP--LGNLTNLEELDLSGNQLTDLPEPLA- 225

                          170
                   ....*....|.
gi 1958764989  240 iifHLRSLESL 250
Cdd:COG4886    226 ---NLTNLETL 233
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 258-985 5.92e-17

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 87.80  E-value: 5.92e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  258 QDRQEAFERFSlEEIERLEKDLEKKTVETEELKNKQTKFLEEI-KHQDKLNKSLKEEAMLQKQScEELESDLNTKKEllk 336
Cdd:TIGR02168  284 EELQKELYALA-NEISRLEQQKQILRERLANLERQLEELEAQLeELESKLDELAEELAELEEKL-EELKEELESLEA--- 358

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  337 qktvELTRACQKQYELEQelafyKIDAKFEPLNYYPSEYAEmdkspdespyIGKSRYKRNmfATETYIVSDAQAVQVRKm 416
Cdd:TIGR02168  359 ----ELEELEAELEELES-----RLEELEEQLETLRSKVAQ----------LELQIASLN--NEIERLEARLERLEDRR- 416

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  417 vpdgGQLRHEHAPRAQAPPDVQLEDTGKQIVAAQTRLSELHHEIEAAEQKVLRATQEFKQLEEAIRQKKISEAEKDLLLK 496
Cdd:TIGR02168  417 ----ERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLD 492

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  497 QLSGRLRHLNKLRQEALDLEAQLEK---------QRKEIAEKHEEINSAQLATDL-------LDSKDPKQSHMKAQKRGK 560
Cdd:TIGR02168  493 SLERLQENLEGFSEGVKALLKNQSGlsgilgvlsELISVDEGYEAAIEAALGGRLqavvvenLNAAKKAIAFLKQNELGR 572

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  561 EQQLDIMNKQYTQLESRLDEILCRIATETEEIKDLEQQ-----------------LTDGQIAANEALKKDLEGVISGLQE 623
Cdd:TIGR02168  573 VTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFdpklrkalsyllggvlvVDDLDNALELAKKLRPGYRIVTLDG 652

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  624 YL----GTIKGQAAQAQNecrklqdekeTLLQRLTEVKQEKDELEIVAMDAENMRKELAELENALQEqhevnasLQQAQG 699
Cdd:TIGR02168  653 DLvrpgGVITGGSAKTNS----------SILERRREIEELEEKIEELEEKIAELEKALAELRKELEE-------LEEELE 715

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  700 DLSAYETELETQLKLKDAETSQLKQELENLVRRTQlEQSVLQTELEKERQSLRDALGKAQSSEEKQQENSE-LRAQLKQL 778
Cdd:TIGR02168  716 QLRKELEELSRQISALRKDLARLEAEVEQLEERIA-QLSKELTELEAEIEELEERLEEAEEELAEAEAEIEeLEAQIEQL 794

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  779 QDDNSLLKKQLKDFQSHLNhvvdglihpeevAARVDELRKRLKLGAGEMRIHSpsdvLGKSLADLQKQF---SEILARSQ 855
Cdd:TIGR02168  795 KEELKALREALDELRAELT------------LLNEEAANLRERLESLERRIAA----TERRLEDLEEQIeelSEDIESLA 858

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  856 WEKEEAQVRERKLHEEMALQQEKLANGQEEFKQACERALEARikfdkrqhnARIQQLENEIHYLQENLKSMEKIQGLTDL 935
Cdd:TIGR02168  859 AEIEELEELIEELESELEALLNERASLEEALALLRSELEELS---------EELRELESKRSELRRELEELREKLAQLEL 929

                          730       740       750       760       770
                   ....*....|....*....|....*....|....*....|....*....|....
gi 1958764989  936 QLQEADEEKERILAQLQELEKKKRREDARSQE----QFLGLDTELKSLKKAVAA 985
Cdd:TIGR02168  930 RLEGLEVRIDNLQERLSEEYSLTLEEAEALENkiedDEEEARRRLKRLENKIKE 983
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 440-1134 6.07e-17

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 87.80  E-value: 6.07e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  440 EDTGKQIVAAQ---TRLSELHHEIEAAEQKVLR---ATQEFKQLEEAIRQKKIS---------EAEKDLLLKQLSGRLRH 504
Cdd:TIGR02168  175 KETERKLERTRenlDRLEDILNELERQLKSLERqaeKAERYKELKAELRELELAllvlrleelREELEELQEELKEAEEE 254

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  505 LNKLRQEALDLEAQLEKQRKEIAEKHEEINSAQLATDLLDSKDPKQSHMKAQKRGKEQQLDIMNKQYT----QLESRLDE 580
Cdd:TIGR02168  255 LEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEaqleELESKLDE 334

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  581 ILCRIATETEEIKDLEQQLTD--GQIAANEALKKDLEGVISGLQEYLGT-------IKGQAAQAQNECRKLQDEKETLLQ 651
Cdd:TIGR02168  335 LAEELAELEEKLEELKEELESleAELEELEAELEELESRLEELEEQLETlrskvaqLELQIASLNNEIERLEARLERLED 414

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  652 RLTEVKQEKDEL--EIVAMDAENMRKELAELENALQEQHEVNASLQQAQGDLSAYETELETQLKLKDAETSQLKQELENL 729
Cdd:TIGR02168  415 RRERLQQEIEELlkKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSL 494

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  730 VRRTQ----LEQSVLQTELEKERQS-LRDALGKAQSSEEKQQENSE--LRAQLKQLQDDNslLKKQLKDFQSHLNHVVDG 802
Cdd:TIGR02168  495 ERLQEnlegFSEGVKALLKNQSGLSgILGVLSELISVDEGYEAAIEaaLGGRLQAVVVEN--LNAAKKAIAFLKQNELGR 572

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  803 LIHPEEVAARVDELR-KRLKLGAGEMRIHSPSDVLGKSLADLQKQFSEILARSQW------------------------- 856
Cdd:TIGR02168  573 VTFLPLDSIKGTEIQgNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLVvddldnalelakklrpgyrivtldg 652

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  857 -------------EKEEAQVRERK-----LHEEMALQQEKLANGQEEFKQAceRALEARIKFDKRQHNARIQQLENEIHY 918
Cdd:TIGR02168  653 dlvrpggvitggsAKTNSSILERRreieeLEEKIEELEEKIAELEKALAEL--RKELEELEEELEQLRKELEELSRQISA 730

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  919 LQENLKSMEKIQGLTDLQLQEADEEKERILAQLQELEKKKRREDARSQEqflgLDTELKSLKKAVAAsdklAAAELTIAK 998
Cdd:TIGR02168  731 LRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAE----AEAEIEELEAQIEQ----LKEELKALR 802

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  999 EQLKSLHGTVMRINQERAEELQEAERSSREAMQAAKDLSRAEAEIELLQHLLREREGQFRDEMENAHVGSKGANLQLLEI 1078
Cdd:TIGR02168  803 EALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNER 882

                          730       740       750       760       770
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1958764989 1079 EALKEAMAKQRAEITRLRDvlnltgtgkkgGIENVVEEIAELRHAVSAQNEYISSM 1134
Cdd:TIGR02168  883 ASLEEALALLRSELEELSE-----------ELRELESKRSELRRELEELREKLAQL 927
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1708-2006 8.10e-17

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 87.30  E-value: 8.10e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1708 QLETNELQSLKLQHDQKVVELEKTQVDLLEGKLELESLQQTAQQQRRELERQRQLLERDRRETERVRAETQALQSCIECL 1787
Cdd:COG1196    221 ELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARL 300

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1788 NKEKEHLQEQceswekksshakrvLAATEESNNTEQSKLGQLEVSVRKLQQELELLSQDKLALHSDSAQEQQQLQDKREA 1867
Cdd:COG1196    301 EQDIARLEER--------------RRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEA 366

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1868 LNSLQKELENTQDHLNLAKQDLMHTTKCQSALLSEQAQLQKDVSQWTARLESCQKETETKEQQLQELQDEIRESKLQLDQ 1947
Cdd:COG1196    367 LLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEE 446

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1958764989 1948 QEMVFQKLQKERESEEQKLVA---SIVSLEQQQGQLERELMDQKSKLEWLLTDVSAAEGRLR 2006
Cdd:COG1196    447 AAEEEAELEEEEEALLELLAElleEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLE 508
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1753-2099 8.38e-17

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 87.30  E-value: 8.38e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1753 RRELERQRQLLERDRRETERVRAetqalqsciecLNKEKEHLQEQCESWEKKSSHAKrvLAATEESNNTEQSKLGQLEVS 1832
Cdd:COG1196    195 LGELERQLEPLERQAEKAERYRE-----------LKEELKELEAELLLLKLRELEAE--LEELEAELEELEAELEELEAE 261

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1833 VRKLQQELEllsqdklalhsdsaQEQQQLQDKREALNSLQKELENTQDHLNLAKQDLMHTTKCQSALLSEQAQLQKDVSQ 1912
Cdd:COG1196    262 LAELEAELE--------------ELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAE 327

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1913 WTARLESCQKETETKEQQLQELQDEIRESKLQLDQQEmvfqKLQKERESEEQKLVASIVSLEQQQGQLERELMDQKSKLE 1992
Cdd:COG1196    328 LEEELEELEEELEELEEELEEAEEELEEAEAELAEAE----EALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLE 403

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1993 WLLTDVSAAEGRLRTLQKEErctESLEKMLSQAKQQLSEREQQLMEKSGDLLALQKEADGMRAdfslLRNQFLTERKKAE 2072
Cdd:COG1196    404 ELEEAEEALLERLERLEEEL---EELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLE----LLAELLEEAALLE 476

                          330       340
                   ....*....|....*....|....*..
gi 1958764989 2073 KQVAGLKEALKIQRSQLEKNLLEQKQE 2099
Cdd:COG1196    477 AALAELLEELAEAAARLLLLLEAEADY 503
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1540-2131 1.43e-16

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 86.53  E-value: 1.43e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1540 EKKEKLTEELQSLQRDIKAAEvnedhhlqvLKESESLLQAKRAELETLKSQVTSQQQELAVLDSQLGHRREELLLLQDSL 1619
Cdd:COG1196    213 ERYRELKEELKELEAELLLLK---------LRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELEL 283

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1620 TQAKADLQEAltlgetevaekcshIREVKSLLEELSFQKgELNVHISERRTQLTLIKQEIEKEEENLEVVLQQLSKHKTE 1699
Cdd:COG1196    284 EEAQAEEYEL--------------LAELARLEQDIARLE-ERRRELEERLEELEEELAELEEELEELEEELEELEEELEE 348

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1700 LKNVADILQLETNELQSLKLQHDQKVVELEKTQVDLLEGKLELESLQQTAQQQRRELERQRQ--LLERDRRETERVRAET 1777
Cdd:COG1196    349 AEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEalLERLERLEEELEELEE 428

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1778 QALQSciecLNKEKEHLQEQCESWEKKSSHAKRVLAATEESNNTEQSKLgQLEVSVRKLQQELELLSQDKLALHSDSAQE 1857
Cdd:COG1196    429 ALAEL----EEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAA-LLEAALAELLEELAEAAARLLLLLEAEADY 503

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1858 QQQLQDKREALNSLQKELENTQDHLNLAKQDLMHT---TKCQSALLSEQAQLQKDVSQWTARLESCQKETETKEQQLQEL 1934
Cdd:COG1196    504 EGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAaleAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIR 583

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1935 QDEIRESKLQLDQQEMVFQKLQKERESEEQKLVASIVSLEQQQGQLERELMDQKSKLEwLLTDVSAAEGRLRTLQKEERC 2014
Cdd:COG1196    584 ARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVT-LAGRLREVTLEGEGGSAGGSL 662

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 2015 TESLEKMLSQAKQQLSEREQQLMEKSGDLLALQKEADGMRADFSLLRNQFLTERKKAEKQVAGLKEALKIQRSQLEKNLL 2094
Cdd:COG1196    663 TGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELL 742

                          570       580       590
                   ....*....|....*....|....*....|....*..
gi 1958764989 2095 EQKQENSCMQKEMATIELVAQDNHERARRLMKELRQM 2131
Cdd:COG1196    743 EEEELLEEEALEELPEPPDLEELERELERLEREIEAL 779
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1335-1877 1.52e-16

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 86.53  E-value: 1.52e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1335 HHLKSKHQEERWLKTSRQHPEKEVEELHRNIDDLVQEKKELELEVEELHRTVERHQQRRDFIDGNVENLMTELEIEKSLK 1414
Cdd:COG1196    232 LKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERR 311

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1415 HH-----EDIVDEIECLEKTLLKRRSELREADRLLAEAESELACTKEKTKSAVEKFTDAKRNLLQTESDAEALEKRAQET 1489
Cdd:COG1196    312 REleerlEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEA 391

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1490 ALNLVKAEQQLRLLQADAEDLEQHKIKQEEILKEINKVVAAKDADFQCLNEKKEKLTEELQSLQRDIKAAEVNEDHHLQV 1569
Cdd:COG1196    392 LRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEE 471

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1570 LKESESLLQAKRAELETLKSQVTSQQQELAVLDSQL-GHRREELLLLQDSLTQAKADLQEALTLGETEVAEKCS--HIRE 1646
Cdd:COG1196    472 AALLEAALAELLEELAEAAARLLLLLEAEADYEGFLeGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAaaLQNI 551

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1647 VKSLLEELSFQKGELNVHISERRTQLTL---IKQEIEKEEENLEVVLQQLSKHKTELKNVADILQLETNEL---QSLKLQ 1720
Cdd:COG1196    552 VVEDDEVAAAAIEYLKAAKAGRATFLPLdkiRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLlgrTLVAAR 631

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1721 HDQKVVELEKTQVDLLEGKLELESLQQTAQQQRRELERQRQLLERDRRETERVRAETQALQScieclnKEKEHLQEQCES 1800
Cdd:COG1196    632 LEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEEL------ELEEALLAEEEE 705

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1958764989 1801 WEKKSSHAKRVLAATEESNNTEQSKLGQLEVSVRKLQQELELLSQDKLALHSDSAQEQQQlqdkREALNSLQKELEN 1877
Cdd:COG1196    706 ERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEEL----ERELERLEREIEA 778
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
82-250 1.94e-16

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 84.21  E-value: 1.94e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989   82 YITEALIKKLTKQDNLALVKSLNLSLSKDGGKKFRYIENLEKCVKLEVLNLSYNliakiEKVDKLLRLRELNLSYNKISK 161
Cdd:COG4886     53 LSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSLLLLGLTDLGDLTNLTELDLSGN-----EELSNLTNLESLDLSGNQLTD 127

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  162 I-EGLENMCNLQKLNLAGNEIEHIPGWFSkKLKSLRVLNLKGNKISSLQDVskLKPLQDLTSLTLIDNPVVALPHYLQfi 240
Cdd:COG4886    128 LpEELANLTNLKELDLSNNQLTDLPEPLG-NLTNLKSLDLSNNQLTDLPEE--LGNLTNLKELDLSNNQITDLPEPLG-- 202

                          170
                   ....*....|
gi 1958764989  241 ifHLRSLESL 250
Cdd:COG4886    203 --NLTNLEEL 210
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 436-1022 1.07e-15

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 83.45  E-value: 1.07e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  436 DVQLEDTGKQIVAAQTRLSELHHEIEAAEQKVLRATQEFKQLEEAIRQKKISEAEKDLLLKQLSGRLRHLNKLRQEALDL 515
Cdd:COG1196    280 ELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAE 359

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  516 EAQLEKQRKEIAEKHEEINSAQLATdlldskdpKQSHMKAQKRGKEQQLDImnkqyTQLESRLDEILCRIATETEEIKDL 595
Cdd:COG1196    360 LAEAEEALLEAEAELAEAEEELEEL--------AEELLEALRAAAELAAQL-----EELEEAEEALLERLERLEEELEEL 426

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  596 EQQLTDGQIAANEALKKDLEgvisglqeylgtIKGQAAQAQNECRKLQDEKETLLQRLTEVKQEKDELEIVAMDAENMRK 675
Cdd:COG1196    427 EEALAELEEEEEEEEEALEE------------AAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLL 494

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  676 ELAELENALQEQHEVNASLQQAQGDLSAYETELETQLKLKDAETSQLKQELENLVRRTQLEQSVLQTELEKERQSLRDAL 755
Cdd:COG1196    495 LLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRA 574

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  756 GKAQSSEEKQQENSELRAQLKQLQDDNSLLKKQLKDFQSHLNHVVDGLIHPEEVAARVDELRKRLKLGAGEMRIHSPSDV 835
Cdd:COG1196    575 TFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGE 654

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  836 LGKSLADLQKQFSEILARSQWEKEEAQVRERKLHEEMALQQEKLANGQEEFKQACERALEARIKfDKRQHNARIQQLENE 915
Cdd:COG1196    655 GGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLE-EELEEEALEEQLEAE 733

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  916 IHYLQENLKSMEKIQGLTDLQLQEADEEKERILAQLQELEKKKRR----------EDARSQEQFLGLDTELKSLKKAvaa 985
Cdd:COG1196    734 REELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEAlgpvnllaieEYEELEERYDFLSEQREDLEEA--- 810

                          570       580       590
                   ....*....|....*....|....*....|....*..
gi 1958764989  986 sdklaaaeltiakeqLKSLHGTVMRINQERAEELQEA 1022
Cdd:COG1196    811 ---------------RETLEEAIEEIDRETRERFLET 832
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1390-2111 4.98e-15

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 81.65  E-value: 4.98e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1390 QQRRDFIDGNVENLMTELEIEKSLKHHEDI---VDEIECLEKTLLKRRSELREaDRLLAEAESELACTKEKTKsavekFT 1466
Cdd:TIGR02169  153 VERRKIIDEIAGVAEFDRKKEKALEELEEVeenIERLDLIIDEKRQQLERLRR-EREKAERYQALLKEKREYE-----GY 226

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1467 DAKRNLLQTESDAEALEKRAQEtalnlvkAEQQLRLLQADAEDLEQHKIKQEEILKEINKVVAAKDADFQC-LNEKKEKL 1545
Cdd:TIGR02169  227 ELLKEKEALERQKEAIERQLAS-------LEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLrVKEKIGEL 299

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1546 TEELQSLQRDIKAAEVNEDHHLQVLKESESLLQAKRAELETLKSQVTSQQQELAVLDSQLGHRREELLLLQDSLTQAKAD 1625
Cdd:TIGR02169  300 EAEIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKE 379

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1626 LQEA---LTLGETEVAEKCSHIREVKSLLEELSFQKGELNVHISERRTQLTLIKQEIEKEEENLEVVLQQLSKHKTELKN 1702
Cdd:TIGR02169  380 FAETrdeLKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQ 459

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1703 VADILQLETNELQSLKlqhdQKVVELEKTQVDLLEGKLELESLQQTAQQQRRELERQRQLLERDR-------RETERVRA 1775
Cdd:TIGR02169  460 LAADLSKYEQELYDLK----EEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIqgvhgtvAQLGSVGE 535

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1776 ETQAL--------------------QSCIECLNKEK----------------------------EHLQEQCESWEKKSSH 1807
Cdd:TIGR02169  536 RYATAievaagnrlnnvvveddavaKEAIELLKRRKagratflplnkmrderrdlsilsedgviGFAVDLVEFDPKYEPA 615

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1808 AKRVLAATEESNNTEQSKlgQLEVSVRKLQQELELL---------SQDKLALHSDSAQEQQQLQDKRE-------ALNSL 1871
Cdd:TIGR02169  616 FKYVFGDTLVVEDIEAAR--RLMGKYRMVTLEGELFeksgamtggSRAPRGGILFSRSEPAELQRLRErleglkrELSSL 693

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1872 QKELENTQDHLNLAKQDLMHTTKCQSALLSEQAQLQKDVSQWTARLESCQKETETKEQQLQELQDEIRESKLQLDQQEMV 1951
Cdd:TIGR02169  694 QSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEED 773

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1952 FQKLQKERESEEQKLVASIVsleQQQGQLERELMDQKSKLEWLLTDVSAAEGRL-RTLQKEERCTESLEKMLSQAKQQLS 2030
Cdd:TIGR02169  774 LHKLEEALNDLEARLSHSRI---PEIQAELSKLEEEVSRIEARLREIEQKLNRLtLEKEYLEKEIQELQEQRIDLKEQIK 850

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 2031 EREQQLMEKSGDLLALQKEADGMRADFSLLRNQFL---TERKKAEKQVAGLKEA---LKIQRSQLEKNLLEQKQENSCMQ 2104
Cdd:TIGR02169  851 SIEKEIENLNGKKEELEEELEELEAALRDLESRLGdlkKERDELEAQLRELERKieeLEAQIEKKRKRLSELKAKLEALE 930


                   ....*..
gi 1958764989 2105 KEMATIE 2111
Cdd:TIGR02169  931 EELSEIE 937
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1834-2133 8.55e-15

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 80.75  E-value: 8.55e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1834 RKLQQELELLSQDKLALHSDSAQEQQQLQDKR-----EALNSLQKELENTQDHLNLAKQDLMHTTKCQSALLSEQAQLQK 1908
Cdd:COG1196    216 RELKEELKELEAELLLLKLRELEAELEELEAEleeleAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLA 295

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1909 DVSQWTARLESCQKETETKEQQLQELQDEIRESKLQLDQQEMVFQKLQKERESEEQKLVASIVSLEQQQGQLERELMDQK 1988
Cdd:COG1196    296 ELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELA 375

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1989 SKLEWLLTDVSAAEGRLRTLQKEERCTESLEKMLSQAKQQLSEREQQLMEKSGDLLALQKEADGMRADFSLLRNQFLTER 2068
Cdd:COG1196    376 EAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELE 455

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1958764989 2069 KKAEKQVAGLKEALKIQRSQLEKNLLEQKQENSCMQKEMATIELVAQDNHERARRLMKELRQMQQ 2133
Cdd:COG1196    456 EEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLR 520
LRR_9 pfam14580
Leucine-rich repeat;
130-279 1.10e-14

Leucine-rich repeat;


Pssm-ID: 405295 [Multi-domain]  Cd Length: 175  Bit Score: 74.03  E-value: 1.10e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  130 LNLSYNLIAKIEKVDKLL-RLRELNLSYNKISKIEGLENMCNLQKLNLAGNEIEHIPGWFSKKLKSLRVLNLKGNKISSL 208
Cdd:pfam14580   24 LDLRGYKIPIIENLGATLdQFDTIDFSDNEIRKLDGFPLLRRLKTLLLNNNRICRIGEGLGEALPNLTELILTNNNLQEL 103

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1958764989  209 QDVSKLKPLQDLTSLTLIDNPVVALPHYLQFIIFHLRSLESLEGQPVTTQDRQEAFERFSLEEIERLEKDL 279
Cdd:pfam14580  104 GDLDPLASLKKLTFLSLLRNPVTNKPHYRLYVIYKVPQLRLLDFRKVKQKERQAAEKMFRSKQGKQLAKEI 174
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1356-2037 1.50e-14

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 80.11  E-value: 1.50e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1356 KEVEELHRNIDDLVQEKKELELEVEELHRTVERHQQRRDFIDGNVENLMTELEIEKSLKhhEDIVDEIECLEKTLLKRRS 1435
Cdd:TIGR02169  294 EKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRR--DKLTEEYAELKEELEDLRA 371

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1436 ELREADRLLAEAESELACTKEKTKSAVEKFTDAKRNLLQTESDAEALEKRAQETALNLVKAEQQLRLLQADAEDLEQHKI 1515
Cdd:TIGR02169  372 ELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIK 451

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1516 KQEEILKEINKVVAAKDADFQCLNEKKEKLTEELQSLQRDIKAAEVNEDHHLQVLKESESLLQAKRAELETLKSQVTS-- 1593
Cdd:TIGR02169  452 KQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQGVHGTVAQlg 531

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1594 --QQQELAVLDSQLGHRreelllLQDSLTQAKADLQEALTLGETEVAEKCSHI--REVKSLLEELSFQKGELNVHISERR 1669
Cdd:TIGR02169  532 svGERYATAIEVAAGNR------LNNVVVEDDAVAKEAIELLKRRKAGRATFLplNKMRDERRDLSILSEDGVIGFAVDL 605

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1670 TQLTLIKQEIEKEEENLEVVLQQLSKHKTELKNV------ADILQLE------TNELQSLKLQHDQKVVELEKTQVDLLE 1737
Cdd:TIGR02169  606 VEFDPKYEPAFKYVFGDTLVVEDIEAARRLMGKYrmvtleGELFEKSgamtggSRAPRGGILFSRSEPAELQRLRERLEG 685

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1738 GKLELESLQQtaqqqrrELERQRQLLERDRRETERVRAETQALQSCIECLNKEKEHLQEQCESWEKKSSHAKRVLAATEE 1817
Cdd:TIGR02169  686 LKRELSSLQS-------ELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKS 758

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1818 SNNTEQSKLGQLEVSVRKLQQELELLSQdklalhSDSAQEQQQLQDKREALNSLQKELENTQDHLNlakQDLMHTTKCQS 1897
Cdd:TIGR02169  759 ELKELEARIEELEEDLHKLEEALNDLEA------RLSHSRIPEIQAELSKLEEEVSRIEARLREIE---QKLNRLTLEKE 829

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1898 ALLSEQAQLQKDVSQWTARLESCQKETETKEQQLQELQDEIRESKLQLDQQEMVFQKLQKERESEEQKLVAsivsLEQQQ 1977
Cdd:TIGR02169  830 YLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRE----LERKI 905

                          650       660       670       680       690       700
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1958764989 1978 GQLERELMDQKSKLEWLLTDVSAAEGRLRTLQKEERCTESL---EKMLSQAKQQLSEREQQLM 2037
Cdd:TIGR02169  906 EELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIpeeELSLEDVQAELQRVEEEIR 968
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 431-1098 2.36e-14

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 79.50  E-value: 2.36e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  431 AQAPPDVQLEDTGKQIVAAQTRLSELHHEIEAAEQKVLRATQEFKQLEEAIRQKKISeaeKDLLLKQLSGRLRHLNKLRQ 510
Cdd:pfam12128  238 KIRPEFTKLQQEFNTLESAELRLSHLHFGYKSDETLIASRQEERQETSAELNQLLRT---LDDQWKEKRDELNGELSAAD 314

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  511 EALdleAQLEKQRKEIAEKH---EEINSAQLATDlLDSKDPKQSHMKAQKRGKEQQLDIMNKQYTQLESRLDEILCRIAT 587
Cdd:pfam12128  315 AAV---AKDRSELEALEDQHgafLDADIETAAAD-QEQLPSWQSELENLEERLKALTGKHQDVTAKYNRRRSKIKEQNNR 390

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  588 ETEEIKDLEQQLTDGQIAANEALKKDLEGVISGLQEylgtikgqaaQAQNECRKLQDEKETLLQRLTEVKQEKDELEIVA 667
Cdd:pfam12128  391 DIAGIKDKLAKIREARDRQLAVAEDDLQALESELRE----------QLEAGKLEFNEEEYRLKSRLGELKLRLNQATATP 460

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  668 MDAENMRKELAELENALQEQHEVNASLQQAQGDLSAYETELETQL-KLKDAE--TSQLKQELENLVRRTQLEQSVLQTEL 744
Cdd:pfam12128  461 ELLLQLENFDERIERAREEQEAANAEVERLQSELRQARKRRDQASeALRQASrrLEERQSALDELELQLFPQAGTLLHFL 540

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  745 EKERQSLRDALGKAQSSEEKQQENSELRAQLKQLQDDNSLLKKQLKdfqshlnhvVDGLIHPEEVAARvDELRKRLklga 824
Cdd:pfam12128  541 RKEAPDWEQSIGKVISPELLHRTDLDPEVWDGSVGGELNLYGVKLD---------LKRIDVPEWAASE-EELRERL---- 606

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  825 gemrihspsDVLGKSL---ADLQKQFSEILARSQWEKEEAQVRE---RKLHEEMALQQEKLANGQEEFKQACERALEARi 898
Cdd:pfam12128  607 ---------DKAEEALqsaREKQAAAEEQLVQANGELEKASREEtfaRTALKNARLDLRRLFDEKQSEKDKKNKALAER- 676

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  899 kfdKRQHNARIQQLENEIHYLQENLKSMEKIQgltDLQLQEADEEKeriLAQLQELEKKKRREDARSQEQFL----GLDT 974
Cdd:pfam12128  677 ---KDSANERLNSLEAQLKQLDKKHQAWLEEQ---KEQKREARTEK---QAYWQVVEGALDAQLALLKAAIAarrsGAKA 747

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  975 ELKSLKKAVAAS-DKLAAAELTIAK--EQLKSLHGTVMRINQERAEELQ----EAERSSREAMQAAKDLSRAEAEIELLQ 1047
Cdd:pfam12128  748 ELKALETWYKRDlASLGVDPDVIAKlkREIRTLERKIERIAVRRQEVLRyfdwYQETWLQRRPRLATQLSNIERAISELQ 827

                          650       660       670       680       690
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1958764989 1048 HLLREREGQFRDEMENAHVGSKGANLQLLEieaLKEAMAKQRAEITRLRDV 1098
Cdd:pfam12128  828 QQLARLIADTKLRRAKLEMERKASEKQQVR---LSENLRGLRCEMSKLATL 875
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1330-2110 5.17e-14

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 78.24  E-value: 5.17e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1330 LEDITHHLKSKhqeERWLKTSRQHPEKEVEELHRNIDDLVQEKKELELEVEELHRTVERHQQRRDFIDGNVENLMTELEI 1409
Cdd:pfam15921   80 LEEYSHQVKDL---QRRLNESNELHEKQKFYLRQSVIDLQTKLQEMQMERDAMADIRRRESQSQEDLRNQLQNTVHELEA 156

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1410 EKSLKHH--EDIVDEIECLEKTLLKRRSELREADRLLAEaeselactkektksavekFTDAKRNLLQTESDAEALEKRAQ 1487
Cdd:pfam15921  157 AKCLKEDmlEDSNTQIEQLRKMMLSHEGVLQEIRSILVD------------------FEEASGKKIYEHDSMSTMHFRSL 218

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1488 ETALNLVkaeqqLRLLQADAEDLEQHKIKQEEILKEINkvvaakdadfqclNEKKEKLTEELQSLQRDIKaaevnedhhl 1567
Cdd:pfam15921  219 GSAISKI-----LRELDTEISYLKGRIFPVEDQLEALK-------------SESQNKIELLLQQHQDRIE---------- 270

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1568 QVLKESESLLQAKRAELETLKSQVTSQQQELAVLDSQLGHRRE----ELLLLQDSLTQAKADLQEALTLGETEVaekcsh 1643
Cdd:pfam15921  271 QLISEHEVEITGLTEKASSARSQANSIQSQLEIIQEQARNQNSmymrQLSDLESTVSQLRSELREAKRMYEDKI------ 344

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1644 irevksllEELSFQKGELNVHISERRTQLTLIKQEIEKEEENLEVVLQQLSKHKTELKnvadiLQLETNEL-------QS 1716
Cdd:pfam15921  345 --------EELEKQLVLANSELTEARTERDQFSQESGNLDDQLQKLLADLHKREKELS-----LEKEQNKRlwdrdtgNS 411

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1717 LKLQHDQKVVELEKTQVDLLEGKleLESLQQTAQQQrreLERQRQLLERDRRETERVRAETQALQSCIECLNKEKEHLQE 1796
Cdd:pfam15921  412 ITIDHLRRELDDRNMEVQRLEAL--LKAMKSECQGQ---MERQMAAIQGKNESLEKVSSLTAQLESTKEMLRKVVEELTA 486

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1797 Q---CESWEKKSSHAKRVLAATEESNNTEQSKLGQLEVSVRKLQQELELLSQDKLALHSDSAQEQQ---QLQDKREALNS 1870
Cdd:pfam15921  487 KkmtLESSERTVSDLTASLQEKERAIEATNAEITKLRSRVDLKLQELQHLKNEGDHLRNVQTECEAlklQMAEKDKVIEI 566

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1871 LQKELENTQdhlnlakQDLMHTTKCQSALLSEQAQLQKDVSQWTARLESCQKETETKEQQLQELqdEIRESKLQLDQQEM 1950
Cdd:pfam15921  567 LRQQIENMT-------QLVGQHGRTAGAMQVEKAQLEKEINDRRLELQEFKILKDKKDAKIREL--EARVSDLELEKVKL 637

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1951 VFQKLQKEReseeqklvaSIVSLEQQQGQLERELMDQKSKLEWLLTDVSAAEGRLRTLQKE-ERCTESLEKMLSQAKQQL 2029
Cdd:pfam15921  638 VNAGSERLR---------AVKDIKQERDQLLNEVKTSRNELNSLSEDYEVLKRNFRNKSEEmETTTNKLKMQLKSAQSEL 708

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 2030 SEREQQLMEKSGDLLALQKEADGMRADFSLLRNQFlterKKAEKQVAGLKEALkiQRSQLEKNLLeqKQENSCMQKEMAT 2109
Cdd:pfam15921  709 EQTRNTLKSMEGSDGHAMKVAMGMQKQITAKRGQI----DALQSKIQFLEEAM--TNANKEKHFL--KEEKNKLSQELST 780


                   .
gi 1958764989 2110 I 2110
Cdd:pfam15921  781 V 781
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 451-1131 5.34e-14

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 78.19  E-value: 5.34e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  451 TRLSELHHEIEAAE--QKVLRATQEFKQLEEAiRQKKISEAEKDLLLKQLSGRLRHLNKLRQEALDLEAQLEKQRKEIAE 528
Cdd:TIGR02169  198 QQLERLRREREKAEryQALLKEKREYEGYELL-KEKEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEE 276

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  529 KHEEIN------SAQLATDLLDSKdPKQSHMKAQKRGKEQQLDIMNKQYTQLESRLDEILcriatetEEIKDLEQQLTDG 602
Cdd:TIGR02169  277 LNKKIKdlgeeeQLRVKEKIGELE-AEIASLERSIAEKERELEDAEERLAKLEAEIDKLL-------AEIEELEREIEEE 348

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  603 QIaaneaLKKDLEGVISGLQEYLGTIKGQAAQAQNECRKLQDEKETLLQRLTEVKQEKDELEivamdaENMRKELAELEN 682
Cdd:TIGR02169  349 RK-----RRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELK------RELDRLQEELQR 417

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  683 ALQEQHEVNASLQQAQGDLSAYETELET-QLKLKDAET--SQLKQELENL---VRRTQLEQSVLQTELEKERQSLRDALG 756
Cdd:TIGR02169  418 LSEELADLNAAIAGIEAKINELEEEKEDkALEIKKQEWklEQLAADLSKYeqeLYDLKEEYDRVEKELSKLQRELAEAEA 497

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  757 KAQSSEEKQQENselRAQLKQLQDDNSLLKKQLKDFQS---------------HLNHVVdglIHPEEVAARVDELRKRLK 821
Cdd:TIGR02169  498 QARASEERVRGG---RAVEEVLKASIQGVHGTVAQLGSvgeryataievaagnRLNNVV---VEDDAVAKEAIELLKRRK 571

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  822 LGA------GEMR-IHSPSDVLGKS--------LADLQKQF---------SEILARSQWEKEE--AQVRERKLHEEMALQ 875
Cdd:TIGR02169  572 AGRatflplNKMRdERRDLSILSEDgvigfavdLVEFDPKYepafkyvfgDTLVVEDIEAARRlmGKYRMVTLEGELFEK 651

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  876 QEKLANGQEEFKQACERALEARIKFdkRQHNARIQQLENEIHYLQENLKSMEKIQGLTDLQLQEADEEKERILAQLQELE 955
Cdd:TIGR02169  652 SGAMTGGSRAPRGGILFSRSEPAEL--QRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLE 729

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  956 KKKRREDARSQEqflgLDTELKSLKKAVAASD--------KLAAAELTIAKEQLK------SLHGTVMRINQERAEELQE 1021
Cdd:TIGR02169  730 QEEEKLKERLEE----LEEDLSSLEQEIENVKselkeleaRIEELEEDLHKLEEAlndleaRLSHSRIPEIQAELSKLEE 805

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1022 AERSSREAMQAA-KDLSRAEAEIELLQHLLREREGQFRD-EMENAHVGSKGANLQlLEIEALKEAMAKQRAEITRLRDVL 1099
Cdd:TIGR02169  806 EVSRIEARLREIeQKLNRLTLEKEYLEKEIQELQEQRIDlKEQIKSIEKEIENLN-GKKEELEEELEELEAALRDLESRL 884

                          730       740       750
                   ....*....|....*....|....*....|..
gi 1958764989 1100 nltgTGKKGGIENVVEEIAELRHAVSAQNEYI 1131
Cdd:TIGR02169  885 ----GDLKKERDELEAQLRELERKIEELEAQI 912
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 808-1101 4.93e-13

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 74.97  E-value: 4.93e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  808 EVAARVDELRKRLKLGAGEMRIHSpsdvlgksLADLQKQFSEILArsqwEKEEAQVRERKLHEEMALQQEKLANGQEEFK 887
Cdd:COG1196    210 EKAERYRELKEELKELEAELLLLK--------LRELEAELEELEA----ELEELEAELEELEAELAELEAELEELRLELE 277

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  888 QACERALEARIKFdkRQHNARIQQLENEIHYLQENLKSMEKIQGLTDLQLQEADEEKERILAQLQELEKKKRREDARSQE 967
Cdd:COG1196    278 ELELELEEAQAEE--YELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEE 355

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  968 QFLGLDTELKSLKKAVAASDKLAAAELTIAKEQLKSLHGTVMRINQERAEELQEAERSSREAMQAAKDLSRAEAEIELLQ 1047
Cdd:COG1196    356 AEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEE 435

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....
gi 1958764989 1048 HLLREREGQFRDEMENAHVGSKGANLQLLEIEALKEAMAKQRAEITRLRDVLNL 1101
Cdd:COG1196    436 EEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEA 489
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 436-1102 7.11e-13

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 74.32  E-value: 7.11e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  436 DVQLEDTGKQIVAAQTRLSELHHEIEAAEQKVLRATQEFKQLEEAIRQKKISEAEKDLLLKQLSGRLRHLNKLRQEALDL 515
Cdd:TIGR02168  308 RERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSK 387

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  516 EAQLEKQ----RKEIAEKHEEINSAQLATDLLDS--KDPKQSHMKAQKRGKEQQLDIMNKQYTQLESRLDEILCRIATET 589
Cdd:TIGR02168  388 VAQLELQiaslNNEIERLEARLERLEDRRERLQQeiEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELR 467

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  590 EEIKDLEQQLTDGQIAANEaLKKDLEGVISGLQEYLGTIKGQAAQAQNecrklQDEKETLLQRLTEV--KQEKDELEIVA 667
Cdd:TIGR02168  468 EELEEAEQALDAAERELAQ-LQARLDSLERLQENLEGFSEGVKALLKN-----QSGLSGILGVLSELisVDEGYEAAIEA 541

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  668 MDAENM------RKELAELENALQEQHEVN------------ASLQQAQGDLSAYETELETQLKLKDAETSQLKQELENL 729
Cdd:TIGR02168  542 ALGGRLqavvveNLNAAKKAIAFLKQNELGrvtflpldsikgTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYL 621

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  730 VRRTQLEQSvLQTELEKERQSLRDAL--------------------GKAQSSEEKQQENSELRAQLKQLQDDNSLLKKQL 789
Cdd:TIGR02168  622 LGGVLVVDD-LDNALELAKKLRPGYRivtldgdlvrpggvitggsaKTNSSILERRREIEELEEKIEELEEKIAELEKAL 700

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  790 KD----FQSHLNHVVDGLIHPEEVAARVDELRKRL-KLGAGEMRIHSPSDVLGKSLADLQKQFSEILARSQWEKEEAQVR 864
Cdd:TIGR02168  701 AElrkeLEELEEELEQLRKELEELSRQISALRKDLaRLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEA 780

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  865 ErklhEEMALQQEKLANGQEEFKQACERALEARikfdkrqhnARIQQLENEIHYLQENLKSMEKIQGLTDLQLQEADEEK 944
Cdd:TIGR02168  781 E----AEIEELEAQIEQLKEELKALREALDELR---------AELTLLNEEAANLRERLESLERRIAATERRLEDLEEQI 847

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  945 ERILAQLQELEKkkrrEDARSQEQFLGLDTELKSLKKAVAASDKLAAAeltiAKEQLKSLHGTVMRINQERAEELQEAER 1024
Cdd:TIGR02168  848 EELSEDIESLAA----EIEELEELIEELESELEALLNERASLEEALAL----LRSELEELSEELRELESKRSELRRELEE 919

                          650       660       670       680       690       700       710
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1958764989 1025 SSREAMQAAKDLSRAEAEIELLQHLLREregQFRDEMENAhvgSKGANLQLLEIEALKEAMAKQRAEITRLRDVlNLT 1102
Cdd:TIGR02168  920 LREKLAQLELRLEGLEVRIDNLQERLSE---EYSLTLEEA---EALENKIEDDEEEARRRLKRLENKIKELGPV-NLA 990
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1871-2143 8.63e-13

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 74.20  E-value: 8.63e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1871 LQKELENTQDHLNLAKQDLMHTTkcQSALLSEQAQLQKDVSQWTARLESCQKETETKEQQLQELQDEIRE---------- 1940
Cdd:COG1196    218 LKEELKELEAELLLLKLRELEAE--LEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEaqaeeyella 295

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1941 SKLQLDQQEMVFQKLQKERESEEQKLVASIVSLEQQQGQLERELMDQKSKLEWLLTDVSAAEGRLRTLQKEERCTESLEK 2020
Cdd:COG1196    296 ELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELA 375

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 2021 MLSQAKQQLSEREQQLMEKSGDLLALQKEADGMRADFSLLRNQFLTERKKAEKQVAGLKEALKIQRSQLEKNLLEQKQEn 2100
Cdd:COG1196    376 EAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAEL- 454

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|...
gi 1958764989 2101 scmQKEMATIELVAQDNHERARRLMKELRQMQQEYLELKKQSW 2143
Cdd:COG1196    455 ---EEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLL 494
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 840-1662 8.93e-13

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 74.32  E-value: 8.93e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  840 LADLQKQFSEILARSQWEKEEAQVRERKLHEEMALQQEKLANGQEEFKQACERALEARIKFDkrQHNARIQQLENEIHYL 919
Cdd:TIGR02168  230 LVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELY--ALANEISRLEQQKQIL 307

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  920 QENLKSMEKIQGLTDLQLQEADEEKERILAQLQELEKK-----------------KRREDARSQEQFLGLDTELKSLKKA 982
Cdd:TIGR02168  308 RERLANLERQLEELEAQLEELESKLDELAEELAELEEKleelkeelesleaeleeLEAELEELESRLEELEEQLETLRSK 387

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  983 VAA---SDKLAAAELTIAKEQLKSLHGTVMRINQERAEELQEAERSSREAMQAakDLSRAEAEIELLQHLLREREGQFRD 1059
Cdd:TIGR02168  388 VAQlelQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQA--ELEELEEELEELQEELERLEEALEE 465

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1060 EMEnahvgskganlqllEIEALKEAMAKQRAEITRLRDVLNLTGTGkKGGIENVVEEIAELRHAVSAQNEYISSMADPVQ 1139
Cdd:TIGR02168  466 LRE--------------ELEEAEQALDAAERELAQLQARLDSLERL-QENLEGFSEGVKALLKNQSGLSGILGVLSELIS 530

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1140 RQGCWyfmppppsskvsshssQATKDSGLGLKCTASTPLRSQQAGQ------QEEKGSSGPLPASgywvyspIRSTPHKS 1213
Cdd:TIGR02168  531 VDEGY----------------EAAIEAALGGRLQAVVVENLNAAKKaiaflkQNELGRVTFLPLD-------SIKGTEIQ 587

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1214 FSKREDADNGGDSQEESGLDDQEDPPFVPPPGYIMYTVLpdgsPVPQGVALYAPSPPLPHSSHPLTP-GTVVYgpppAGA 1292
Cdd:TIGR02168  588 GNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVL----VVDDLDNALELAKKLRPGYRIVTLdGDLVR----PGG 659

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1293 PIIYGPPPANfavplisMGVQHCNIpEHRDLENEVSRLEDITHHLKSKHQEerwLKTSRQHPEKEVEELHRNIDDLVQEK 1372
Cdd:TIGR02168  660 VITGGSAKTN-------SSILERRR-EIEELEEKIEELEEKIAELEKALAE---LRKELEELEEELEQLRKELEELSRQI 728

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1373 KELELEVEELHRTVERHQQRRDFIDGNVENLMTELE-----IEKSLKHHEDIVDEIECLEKTLLKRRSELREADRLLAEA 1447
Cdd:TIGR02168  729 SALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEeleerLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDEL 808

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1448 ESELACTKektksavEKFTDAKRNLLQTESDAEALEKRAQETALNLVKAEQQLRLLQADAEDLEQHKIKQEEILKEINKV 1527
Cdd:TIGR02168  809 RAELTLLN-------EEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNE 881

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1528 VAAKDADFQCLNEKKEKLTEELQSLQRDIKAAEVNEDHHLQVLKESESLLQAKRAELETLKSQVTSQQQ-ELAVLDSQLG 1606
Cdd:TIGR02168  882 RASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSlTLEEAEALEN 961

                          810       820       830       840       850
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1958764989 1607 HRREELLLLQDSLTQAKADLQEALTLGETEVAEkcshIREVKSLLEELSFQKGELN 1662
Cdd:TIGR02168  962 KIEDDEEEARRRLKRLENKIKELGPVNLAAIEE----YEELKERYDFLTAQKEDLT 1013
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 723-1654 1.64e-12

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 73.17  E-value: 1.64e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  723 KQELENLVRRTQ--LEQ-SVLQTELEKERQSLrdalgKAQSseEKQQENSELRAQLKQLQddNSLLKKQLKDFQSHLnhv 799
Cdd:TIGR02168  174 RKETERKLERTRenLDRlEDILNELERQLKSL-----ERQA--EKAERYKELKAELRELE--LALLVLRLEELREEL--- 241

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  800 vdglihpEEVAARVDELRKRLKLGAGEMrihspsDVLGKSLADLQKQFSEIlarsqweKEEAQVRERKLHEEMALQQEKl 879
Cdd:TIGR02168  242 -------EELQEELKEAEEELEELTAEL------QELEEKLEELRLEVSEL-------EEEIEELQKELYALANEISRL- 300

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  880 aNGQEEFKQACERALEARIKfdkrQHNARIQQLENEIHYLQENLKSMEKiqgltdlQLQEADEEKERILAQLQELEKKKR 959
Cdd:TIGR02168  301 -EQQKQILRERLANLERQLE----ELEAQLEELESKLDELAEELAELEE-------KLEELKEELESLEAELEELEAELE 368

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  960 REDARSQEqflgLDTELKSLKKAVAA---SDKLAAAELTIAKEQLKSLHGTVMRINQERAEELQEAERSSREAMQAakDL 1036
Cdd:TIGR02168  369 ELESRLEE----LEEQLETLRSKVAQlelQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQA--EL 442

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1037 SRAEAEIELLQHLLREREGQFRDEMEnahvgskganlqllEIEALKEAMAKQRAEITRLRDVLNLTGTGKkGGIENVVEE 1116
Cdd:TIGR02168  443 EELEEELEELQEELERLEEALEELRE--------------ELEEAEQALDAAERELAQLQARLDSLERLQ-ENLEGFSEG 507

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1117 IAELRHAVSAQNEYISSMADPVQRQGCWyfmppppsskvsshssQATKDSGLGLKCTASTPLRSQQAGQ------QEEKG 1190
Cdd:TIGR02168  508 VKALLKNQSGLSGILGVLSELISVDEGY----------------EAAIEAALGGRLQAVVVENLNAAKKaiaflkQNELG 571

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1191 SSGPLPASgywvyspIRSTPHKSFSKREDADNGGDSQEESGLDDQEDPPFVPPPGYIMYTVLPdgspVPQGVALYAPSPP 1270
Cdd:TIGR02168  572 RVTFLPLD-------SIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLV----VDDLDNALELAKK 640

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1271 LPHSSHPLTP-GTVVYgpppAGAPIIYGPPPANfavplisMGVQHCNIpEHRDLENEVSRLEDITHHLKSKHQEerwLKT 1349
Cdd:TIGR02168  641 LRPGYRIVTLdGDLVR----PGGVITGGSAKTN-------SSILERRR-EIEELEEKIEELEEKIAELEKALAE---LRK 705

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1350 SRQHPEKEVEELHRNIDDLVQEKKELELEVEELHRTVERHQQRRDFIDGNVENLMTELEIEkslkhhedivdeieclekt 1429
Cdd:TIGR02168  706 ELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEEL------------------- 766

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1430 llkrRSELREADRLLAEAESELACTKEKTKSAVEKFTDAKRNLLQTESDAEALEKRAQETALNLVKAEQQLRLLQADAED 1509
Cdd:TIGR02168  767 ----EERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLED 842

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1510 LEQHKIKQEEILKEINKVVAAKDADFQCLNEKKEKLTEELQSLQRDIKAAEVNEDHHLQVLKESESLLQAKRAELETLKS 1589
Cdd:TIGR02168  843 LEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELRE 922

                          890       900       910       920       930       940
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1958764989 1590 QVTSQQQELAVLDSQLGHRREELlllqdsLTQAKADLQEALTLGETEVAEKCSHIREVKSLLEEL 1654
Cdd:TIGR02168  923 KLAQLELRLEGLEVRIDNLQERL------SEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKI 981
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1337-1947 2.24e-12

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 72.78  E-value: 2.24e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1337 LKSKHQEERWLKTSRQHPEKEVEELHRNIDDLVQEKKELELEVEELHRTVERHQQRRDFIDGNVENLMTELEIEKSLKHH 1416
Cdd:TIGR02168  360 LEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQ 439

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1417 EDIVDEIECLEKTllkrRSELREADRLLAEAESELACTKEKTKSAVEKFTDAKRNLLQTESDAEALEKRaQETALNLVKA 1496
Cdd:TIGR02168  440 AELEELEEELEEL----QEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGF-SEGVKALLKN 514

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1497 EQQLRLLQADAEDL----EQHKIKQEEILKEI--NKVVAAKDADFQCLNEKKEKLTEELQSLQRDIKAAEVNEDHHLQVL 1570
Cdd:TIGR02168  515 QSGLSGILGVLSELisvdEGYEAAIEAALGGRlqAVVVENLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREIL 594

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1571 KESESLLQAkraeletLKSQVTSQQQELAVLDSQLGHrreelLLLQDSLTQA---------------------------- 1622
Cdd:TIGR02168  595 KNIEGFLGV-------AKDLVKFDPKLRKALSYLLGG-----VLVVDDLDNAlelakklrpgyrivtldgdlvrpggvit 662

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1623 -KADLQEALTLG-ETEVAEKCSHIREVKSLLEELSFQKGELNVHISERRTQLTLIKQEIEKEEENLEVVLQQLSKHKTEL 1700
Cdd:TIGR02168  663 gGSAKTNSSILErRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEV 742

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1701 KNVADILQLETNELQSLKLQHDQKVVELEKTQVDLLEGKLELESLQQTAQQQRRELERQRQLLERDRRETERVRAETQAL 1780
Cdd:TIGR02168  743 EQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANL 822

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1781 QSCIECLNKEKEHLQEQCESWEKKSSHAKRVLAATEESNNTEQSKLGQLEVSVRKLQQELELLSQDKLALHSDSAQEQQQ 1860
Cdd:TIGR02168  823 RERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEE 902

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1861 LQDKREALNSLQKELENTQDHLNLAKQDLmhttkcQSALLSEQAQLQKDVSQWTARLESCQKETETKEQQLQELQDEIRE 1940
Cdd:TIGR02168  903 LRELESKRSELRRELEELREKLAQLELRL------EGLEVRIDNLQERLSEEYSLTLEEAEALENKIEDDEEEARRRLKR 976


                   ....*..
gi 1958764989 1941 SKLQLDQ 1947
Cdd:TIGR02168  977 LENKIKE 983
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
83-250 3.79e-12

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 70.73  E-value: 3.79e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989   83 ITEALIKKLTKQDNLALVKSLNLSLSKDGGKKFRYIENLEKCVKLEVLNLSYNLIAKIEKVDKLLRLRELNLSYNkiski 162
Cdd:COG4886     32 LLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSLLLLGLTDLGDLTNLTELDLSGN----- 106

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  163 EGLENMCNLQKLNLAGNEIEHIPGWFSkKLKSLRVLNLKGNKISSLQDVskLKPLQDLTSLTLIDNPVVALPHylqfIIF 242
Cdd:COG4886    107 EELSNLTNLESLDLSGNQLTDLPEELA-NLTNLKELDLSNNQLTDLPEP--LGNLTNLKSLDLSNNQLTDLPE----ELG 179


                   ....*...
gi 1958764989  243 HLRSLESL 250
Cdd:COG4886    180 NLTNLKEL 187
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 270-824 6.09e-12

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 71.51  E-value: 6.09e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  270 EEIERLEKDLEKKTVETEELKNKQTKFLEEIKHQDKLNKSLKEEAMLQKQSCEELESDLNTKKELLKQKTVELTRACQKQ 349
Cdd:COG1196    246 AELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEEL 325

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  350 YELEQELAfyKIDAKFEplnyypseyAEMDKSPDESPYIGKSRYKRNMFATETYIVSDAQAVQVRKMvpDGGQLRHEHAP 429
Cdd:COG1196    326 AELEEELE--ELEEELE---------ELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEEL--EELAEELLEAL 392

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  430 RAQAPPDVQLEDTGKQIVAAQTRLSELHHEIEAAEQKVLRATQEFKQLEEAIRQKKISEAEKDLLLKQLSGRLRHLNKLR 509
Cdd:COG1196    393 RAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEA 472

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  510 QEALDLEAQLEKQRKEIAEKHEEINSAQlATDLLDSKDPKQSHMKAQKRGKEQQLDIM----NKQYTQLESRLDEILCRI 585
Cdd:COG1196    473 ALLEAALAELLEELAEAAARLLLLLEAE-ADYEGFLEGVKAALLLAGLRGLAGAVAVLigveAAYEAALEAALAAALQNI 551

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  586 ATETEEIkdleqqltdgQIAANEALKKDLEGVISGLQeyLGTIKGQAAQAQNECRKLQDEKETLLQRLTEVKQEKDELEI 665
Cdd:COG1196    552 VVEDDEV----------AAAAIEYLKAAKAGRATFLP--LDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLG 619

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  666 VAMDAENMRKELAELENALQEQHEVNASLQQAQGDLSAYETELETQLKLKDAETSQLKQELENLVRRTQLEQSVLQTELE 745
Cdd:COG1196    620 DTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEAL 699

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  746 KERQSLRDALGKAQSSEEKQQENSELRAQLKQLQDDNsLLKKQLKDFQSHLNHVVDGLIHP---EEVAARVDELRKRLK- 821
Cdd:COG1196    700 LAEEEEERELAEAEEERLEEELEEEALEEQLEAEREE-LLEELLEEEELLEEEALEELPEPpdlEELERELERLEREIEa 778


                   ...
gi 1958764989  822 LGA 824
Cdd:COG1196    779 LGP 781
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1763-2141 1.84e-11

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 69.71  E-value: 1.84e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1763 LERDRRETERVRAETQALQSCIECLNKEKEHLQEQCESWEKksshakrvlaateesnnteqsklgQLEVSVRKLQQELEL 1842
Cdd:TIGR02169  172 KEKALEELEEVEENIERLDLIIDEKRQQLERLRREREKAER------------------------YQALLKEKREYEGYE 227

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1843 LSQDKLALHSDSAQEQQQLQDKREALNSLQKELENTQDHLNLAKQDLMHTTKCQSALLS-EQAQLQKDVSQWTARLESCQ 1921
Cdd:TIGR02169  228 LLKEKEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEeEQLRVKEKIGELEAEIASLE 307

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1922 KETETKEQQLQELQDEIRESKLQLDQQEMVFQKLqkERESEEQKLvasivsleqQQGQLERELMDQKSKLEWLLTDVSAA 2001
Cdd:TIGR02169  308 RSIAEKERELEDAEERLAKLEAEIDKLLAEIEEL--EREIEEERK---------RRDKLTEEYAELKEELEDLRAELEEV 376

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 2002 EGRLRTLQKEercteslekmLSQAKQQLSEREQQLMEKSGDLLALQKEADGMRADFSLLRNQFlterKKAEKQVAGLKEA 2081
Cdd:TIGR02169  377 DKEFAETRDE----------LKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAI----AGIEAKINELEEE 442

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 2082 LKIQRSQLEKnlleQKQENSCMQKEMATIELVAQDNHERARRLMKELRQMQQEYLELKKQ 2141
Cdd:TIGR02169  443 KEDKALEIKK----QEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQ 498
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1323-1804 2.76e-11

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 68.94  E-value: 2.76e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1323 LENEVSRLEDITHHLKSKHQEERWLKTSRQHPEKEVEELHRNIDDLVQEKKELELEVEELHRTVERHQQRRDFIDGNVEN 1402
Cdd:PRK03918   195 IKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEELKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKE 274

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1403 LMTELEIEKSLKHHEDIVDEIECLEKTLLKRRSELREADRLLAEAESELACTKEKTKSAVEK----------FTDAKRNL 1472
Cdd:PRK03918   275 IEELEEKVKELKELKEKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEERIKELEEKeerleelkkkLKELEKRL 354

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1473 LQTESDAEALEK-RAQETALNLVKAEQQLRLLQADAEDLEQHKIKQEEILKEINKVVAAKDADFQCLNEKKEKLtEELQS 1551
Cdd:PRK03918   355 EELEERHELYEEaKAKKEELERLKKRLTGLTPEKLEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAI-EELKK 433

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1552 LQRD--IKAAEVNEDHHLQVLKESESLLQAKRAELETLKSQVTSQQQELAVLDSQLGHRREELLLLQD------------ 1617
Cdd:PRK03918   434 AKGKcpVCGRELTEEHRKELLEEYTAELKRIEKELKEIEEKERKLRKELRELEKVLKKESELIKLKELaeqlkeleeklk 513

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1618 --SLTQAKADLQEALTLGE---------TEVAEKCSHIREVKSLLEELSFQKGELNVHISERRTQLTLIKQEIEKEEENL 1686
Cdd:PRK03918   514 kyNLEELEKKAEEYEKLKEkliklkgeiKSLKKELEKLEELKKKLAELEKKLDELEEELAELLKELEELGFESVEELEER 593

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1687 EVVLQQLSKHKTELKNVADILQLETNELQSLKLQHDQKVVELEKTQVDLLEGKLELESLQQTAQQQrrELERQRQLLERD 1766
Cdd:PRK03918   594 LKELEPFYNEYLELKDAEKELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEELEKKYSEE--EYEELREEYLEL 671

                          490       500       510
                   ....*....|....*....|....*....|....*...
gi 1958764989 1767 RRETERVRAETQALQSCIECLNKEKEHLQEQCESWEKK 1804
Cdd:PRK03918   672 SRELAGLRAELEELEKRREEIKKTLEKLKEELEEREKA 709
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 584-970 7.39e-11

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 67.77  E-value: 7.39e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  584 RIATETEEIKDLEQQLTDGQIAANEALKK--DLEGVISGLQEYLGTIKGQAAQAQNECRKLQDEKETLLQRLTEVKQEKD 661
Cdd:TIGR02168  678 EIEELEEKIEELEEKIAELEKALAELRKEleELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELT 757

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  662 ELEIVAMDAENMRKEL-AELENALQEQHEVNASLQQAQGDLSAYET---ELETQLKLKDAETSQLKQELENLVRRTQLEQ 737
Cdd:TIGR02168  758 ELEAEIEELEERLEEAeEELAEAEAEIEELEAQIEQLKEELKALREaldELRAELTLLNEEAANLRERLESLERRIAATE 837

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  738 SVLqTELEKERQSLRDALGKAQSSEEKQQEN-SELRAQLKQLQDDNSLLKKQLKDFQSHLNHVVDGLihpEEVAARVDEL 816
Cdd:TIGR02168  838 RRL-EDLEEQIEELSEDIESLAAEIEELEELiEELESELEALLNERASLEEALALLRSELEELSEEL---RELESKRSEL 913

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  817 RKRLKLgagemrihspsdvlgksladLQKQFSEILARsqweKEEAQVRERKLHEEMALQQEKLANGQEEfkqaceraLEA 896
Cdd:TIGR02168  914 RRELEE--------------------LREKLAQLELR----LEGLEVRIDNLQERLSEEYSLTLEEAEA--------LEN 961

                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1958764989  897 RIKFDKRQHNARIQQLENEIHYLQE-NLKSMEKIQGLTDlQLQEADEEKERILAQLQELEKKKRREDARSQEQFL 970
Cdd:TIGR02168  962 KIEDDEEEARRRLKRLENKIKELGPvNLAAIEEYEELKE-RYDFLTAQKEDLTEAKETLEEAIEEIDREARERFK 1035
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
497-1060 1.27e-10

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 67.25  E-value: 1.27e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  497 QLSGRLRHLNKLRQEALDLEAQLEkQRKEIAEKHEEINSAQLATDLLDSKDPKQSHMKAQKRgkeqqldimnkqYTQLES 576
Cdd:COG4913    229 ALVEHFDDLERAHEALEDAREQIE-LLEPIRELAERYAAARERLAELEYLRAALRLWFAQRR------------LELLEA 295

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  577 RLDEIlcriateTEEIKDLEQQltdgqIAANEALKKDLEGVISGLQEYLGTIKGQA-AQAQNECRKLQDEKETLLQRLTE 655
Cdd:COG4913    296 ELEEL-------RAELARLEAE-----LERLEARLDALREELDELEAQIRGNGGDRlEQLEREIERLERELEERERRRAR 363

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  656 VKQEkdeLEIVAMDAENMRKELAELENALQEQHEvnaSLQQAQGDLSAYETELETQLKLKDAETSQLKQELENLVRRtql 735
Cdd:COG4913    364 LEAL---LAALGLPLPASAEEFAALRAEAAALLE---ALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERR--- 434

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  736 eQSVLQTELEKERQSLRDALGKAQS------------SEEK--------------------------------------- 764
Cdd:COG4913    435 -KSNIPARLLALRDALAEALGLDEAelpfvgelievrPEEErwrgaiervlggfaltllvppehyaaalrwvnrlhlrgr 513

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  765 ---QQENSELRAQLKQLQDDNSLLKK---QLKDFQSHLNHVvdgLIHPEEVA--ARVDELRK-----------RLKLGAG 825
Cdd:COG4913    514 lvyERVRTGLPDPERPRLDPDSLAGKldfKPHPFRAWLEAE---LGRRFDYVcvDSPEELRRhpraitragqvKGNGTRH 590

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  826 EM--RIHSPSD-VLGKS----LADLQKQfseiLARSQWEKEEAQVRERKLHEEMALQQEKLANgqeefKQACERALEARI 898
Cdd:COG4913    591 EKddRRRIRSRyVLGFDnrakLAALEAE----LAELEEELAEAEERLEALEAELDALQERREA-----LQRLAEYSWDEI 661

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  899 kfDKRQHNARIQQLENEihyLQENLKSMEKIQGLTDlQLQEADEEKERILAQLQELEKKKRRedarsqeqflgLDTELKS 978
Cdd:COG4913    662 --DVASAEREIAELEAE---LERLDASSDDLAALEE-QLEELEAELEELEEELDELKGEIGR-----------LEKELEQ 724

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  979 LKKAV-AASDKLAAAELTIAKEQLKSLhgtvmrinQERAEELQEAERSSREAMQAAKDLSRAEAEIELLQHLLREREGQF 1057
Cdd:COG4913    725 AEEELdELQDRLEAAEDLARLELRALL--------EERFAAALGDAVERELRENLEERIDALRARLNRAEEELERAMRAF 796


                   ...
gi 1958764989 1058 RDE 1060
Cdd:COG4913    797 NRE 799
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 1431-2043 2.59e-10

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 66.15  E-value: 2.59e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1431 LKRRSELREADRLLAEAESELACTKEKTKS-----AVEKFTDAKRNLLQTESDAEALEKRAQETALNLVKAEQQLRLLQA 1505
Cdd:TIGR00618  256 LKKQQLLKQLRARIEELRAQEAVLEETQERinrarKAAPLAAHIKAVTQIEQQAQRIHTELQSKMRSRAKLLMKRAAHVK 335

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1506 DAEDLEQHKIKQEEILKE--INKVVAAKDADFQCLNEKKEKLTEELQSLQRDIKAAEvnedHHLQVLKESESLLQAKRAE 1583
Cdd:TIGR00618  336 QQSSIEEQRRLLQTLHSQeiHIRDAHEVATSIREISCQQHTLTQHIHTLQQQKTTLT----QKLQSLCKELDILQREQAT 411

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1584 LETLKSQVTSQQQELAVLDSQLGHRREELLLLQ-------DSLTQAKADLQEA------LTLGETEVAEKCSHIREVKSL 1650
Cdd:TIGR00618  412 IDTRTSAFRDLQGQLAHAKKQQELQQRYAELCAaaitctaQCEKLEKIHLQESaqslkeREQQLQTKEQIHLQETRKKAV 491

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1651 ----LEELSFQKGELNVHISERRTQLTLIKQEIEKEEENLEVvLQQLSKHKTELKNVADILQLETNELQSLKLQHDQKVV 1726
Cdd:TIGR00618  492 vlarLLELQEEPCPLCGSCIHPNPARQDIDNPGPLTRRMQRG-EQTYAQLETSEEDVYHQLTSERKQRASLKEQMQEIQQ 570

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1727 ELEKTQVDLLEGKLELESLQQTAQQQRRELERQ----RQLLERDRRETERVRAE------TQALQSCIECLNKEKEHLQE 1796
Cdd:TIGR00618  571 SFSILTQCDNRSKEDIPNLQNITVRLQDLTEKLseaeDMLACEQHALLRKLQPEqdlqdvRLHLQQCSQELALKLTALHA 650

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1797 QCES--WEKKSSHAKRVLAATEESNNTEQSKLGQLEVSVRKLQQELELLSQDKLALHSDSAQEQQ---QLQDKREALNSL 1871
Cdd:TIGR00618  651 LQLTltQERVREHALSIRVLPKELLASRQLALQKMQSEKEQLTYWKEMLAQCQTLLRELETHIEEydrEFNEIENASSSL 730

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1872 QKELENTQDHLNLAKQDLMHTTKCQsalLSEQAQLQKDVSQwtarlescqkETETKEQQLQELQDEIRESKLQLDQQEMV 1951
Cdd:TIGR00618  731 GSDLAAREDALNQSLKELMHQARTV---LKARTEAHFNNNE----------EVTAALQTGAELSHLAAEIQFFNRLREED 797

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1952 FQKLQKERESEEQKLVASIVSLEQQQGQLERELMDQKSKLEWLltdvSAAEGRLRTLQKEERCTeslekmlSQAKQQLSE 2031
Cdd:TIGR00618  798 THLLKTLEAEIGQEIPSDEDILNLQCETLVQEEEQFLSRLEEK----SATLGEITHQLLKYEEC-------SKQLAQLTQ 866

                          650
                   ....*....|..
gi 1958764989 2032 REQQLMEKSGDL 2043
Cdd:TIGR00618  867 EQAKIIQLSDKL 878
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
119-244 2.97e-10

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 64.95  E-value: 2.97e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  119 ENLEKCVKLEVLNLSYNLIAKIEKVDKLLRLRELNLSYNKISKIEGLENMCNLQKLNLAGNEIEHIPGWFSKKLKSLRVL 198
Cdd:COG4886    222 EPLANLTNLETLDLSNNQLTDLPELGNLTNLEELDLSNNQLTDLPPLANLTNLKTLDLSNNQLTDLKLKELELLLGLNSL 301

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*.
gi 1958764989  199 NLKGNKISSLQDVSKLKPLQDLTSLTLIDNPVVALPHYLQFIIFHL 244
Cdd:COG4886    302 LLLLLLLNLLELLILLLLLTTLLLLLLLLKGLLVTLTTLALSLSLL 347
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 1355-2127 4.30e-10

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 65.45  E-value: 4.30e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1355 EKEVEELHRNIDDLVQEKKELELEVEELHRTVERHQQRRDFIDGNVENLMTELEIEkSLKHHEDIVDEIECLEKTLLKRR 1434
Cdd:TIGR00606  325 QRELEKLNKERRLLNQEKTELLVEQGRLQLQADRHQEHIRARDSLIQSLATRLELD-GFERGPFSERQIKNFHTLVIERQ 403

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1435 S-ELREADRLLAEAESELACTKEktksAVEKFTDAKRNLLQT-ESDAEALEKRaQETALNLVKAEQQLRLLQADAEDLEQ 1512
Cdd:TIGR00606  404 EdEAKTAAQLCADLQSKERLKQE----QADEIRDEKKGLGRTiELKKEILEKK-QEELKFVIKELQQLEGSSDRILELDQ 478

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1513 HKIKQEEILKEinkvvAAKDADFQCLNEKKEKLTEELQSLQRDIKA-AEVNE--DHHLQVLKESESLLQAKRAELETLKS 1589
Cdd:TIGR00606  479 ELRKAERELSK-----AEKNSLTETLKKEVKSLQNEKADLDRKLRKlDQEMEqlNHHTTTRTQMEMLTKDKMDKDEQIRK 553

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1590 QVTSQQQELA----------VLDSQLGHRREELLLLQDSLTQAKADLQEALTLgetevaeKCSHIREVKSLLEELSFQKG 1659
Cdd:TIGR00606  554 IKSRHSDELTsllgyfpnkkQLEDWLHSKSKEINQTRDRLAKLNKELASLEQN-------KNHINNELESKEEQLSSYED 626

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1660 ELNVHISERRTQLTLIKQEIEkeeenlevvLQQLSKHKTELKNVADILQLETNELQSLKLQHDQKVVELEKTQVDLLEGK 1739
Cdd:TIGR00606  627 KLFDVCGSQDEESDLERLKEE---------IEKSSKQRAMLAGATAVYSQFITQLTDENQSCCPVCQRVFQTEAELQEFI 697

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1740 LELESLQQTAQQQRRELERQRQLLERdRRETERVRAETQalQSCIECLNKEKEHLQEQCESWEKKSSHAKRVLAATEESN 1819
Cdd:TIGR00606  698 SDLQSKLRLAPDKLKSTESELKKKEK-RRDEMLGLAPGR--QSIIDLKEKEIPELRNKLQKVNRDIQRLKNDIEEQETLL 774

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1820 NTEQSKLGQLEVS------VRKLQQELELLSQ--DKLALHSDSA-------QEQQQLQDKREALNSLQKELENTQDHLNL 1884
Cdd:TIGR00606  775 GTIMPEEESAKVCltdvtiMERFQMELKDVERkiAQQAAKLQGSdldrtvqQVNQEKQEKQHELDTVVSKIELNRKLIQD 854

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1885 AKQDLMHTTKCQSALLSEQAQLQKDVsqwtARLESCQKETETKEQQLQELQDEIRESKLQLDQQEMVFQKLQKERESeeq 1964
Cdd:TIGR00606  855 QQEQIQHLKSKTNELKSEKLQIGTNL----QRRQQFEEQLVELSTEVQSLIREIKDAKEQDSPLETFLEKDQQEKEE--- 927

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1965 klvaSIVSLEQQQGQLERELMDQKSKLEWLLTDVSAAEGRLRtlQKEERCTESLEKMLSQAKQQLSEREQQLMEKSGDLL 2044
Cdd:TIGR00606  928 ----LISSKETSNKKAQDKVNDIKEKVKNIHGYMKDIENKIQ--DGKDDYLKQKETELNTVNAQLEECEKHQEKINEDMR 1001

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 2045 ALQKEADGMRADFSLLRNQFltERKKAEKQVAGLKEALKIQRSQL-EKNLLEQKQENSCMQKEMATIelvaQDNHERARR 2123
Cdd:TIGR00606 1002 LMRQDIDTQKIQERWLQDNL--TLRKRENELKEVEEELKQHLKEMgQMQVLQMKQEHQKLEENIDLI----KRNHVLALG 1075


                   ....
gi 1958764989 2124 LMKE 2127
Cdd:TIGR00606 1076 RQKG 1079
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
509-1121 4.37e-10

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 65.06  E-value: 4.37e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  509 RQEAL-DLEAQLEkqRKEIAEKHEEINSAQLAtdlLDSKDPKQSHMKAQKRGKEQQLDimnkqytqlesRLDEILCRIAT 587
Cdd:PRK02224   185 QRGSLdQLKAQIE--EKEEKDLHERLNGLESE---LAELDEEIERYEEQREQARETRD-----------EADEVLEEHEE 248

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  588 ETEEIKDLEQQLTDGQ--IAANEALKKDLEGVISGLQEYLGTIKGQAAQAQNECRKLQDEKETLLQRLTEVKQEKDELei 665
Cdd:PRK02224   249 RREELETLEAEIEDLRetIAETEREREELAEEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEEL-- 326

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  666 vamdaenmRKELAELENALQEQHEVNASLQQAQGDLSAYETELETQLKLKDAETSQLKQELENlvRRTQLEqsvlqtELE 745
Cdd:PRK02224   327 --------RDRLEECRVAAQAHNEEAESLREDADDLEERAEELREEAAELESELEEAREAVED--RREEIE------ELE 390

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  746 KERQSLRDALGKAQSSEEKQQENSELraqlkqLQDDNSLLKKQLKDFQSHLnhvvdglihpEEVAARVDELRKRLKLGag 825
Cdd:PRK02224   391 EEIEELRERFGDAPVDLGNAEDFLEE------LREERDELREREAELEATL----------RTARERVEEAEALLEAG-- 452

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  826 emriHSPSdvLGKSLADlqkqfSEILARSQWEKEEAQVRERKLhEEMALQQEKLANGQEEFKQACERALEARIKFDKRQH 905
Cdd:PRK02224   453 ----KCPE--CGQPVEG-----SPHVETIEEDRERVEELEAEL-EDLEEEVEEVEERLERAEDLVEAEDRIERLEERRED 520

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  906 -NARIQQLENEIHYLQENLKSMEKiqgltDLQLQEADEEKERILAQLQELEKKKRREDARSQEQFLG-LDTELKSLKKAV 983
Cdd:PRK02224   521 lEELIAERRETIEEKRERAEELRE-----RAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLAeLKERIESLERIR 595

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  984 AASDKLAAAEltiakEQLKSLhgtvmrinQERAEELQEAERSSREAMQAakdlsraeaeiellqhlLREREGQFRDEMEN 1063
Cdd:PRK02224   596 TLLAAIADAE-----DEIERL--------REKREALAELNDERRERLAE-----------------KRERKRELEAEFDE 645

                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1064 AHVGSKGANLQLLE--IEALKEAMAKQRAEITRLRDvlnltgtgKKGGIENVVEEIAELR 1121
Cdd:PRK02224   646 ARIEEAREDKERAEeyLEQVEEKLDELREERDDLQA--------EIGAVENELEELEELR 697
LRR_8 pfam13855
Leucine rich repeat;
148-205 1.21e-09

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 55.99  E-value: 1.21e-09
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1958764989  148 RLRELNLSYNKISKIEG--LENMCNLQKLNLAGNEIEHI-PGWFSKkLKSLRVLNLKGNKI 205
Cdd:pfam13855    2 NLRSLDLSNNRLTSLDDgaFKGLSNLKVLDLSNNLLTTLsPGAFSG-LPSLRYLDLSGNRL 61
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1921-2141 1.30e-09

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 62.47  E-value: 1.30e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1921 QKETETKEQQLQELQDEIRESKLQLDQQEMVFQKLQKERESEEQKlvasIVSLEQQQGQLERELMDQKSKLEWLLTDVSA 2000
Cdd:COG4942     19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERR----IAALARRIRALEQELAALEAELAELEKEIAE 94

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 2001 AEGRLRTLQKEerctesLEKMLSQAKQQLSEREQQLMEKSGDLLALQKEADGMRAdFSLLRNQFLTERKKAEKQVAGLKE 2080
Cdd:COG4942     95 LRAELEAQKEE------LAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKY-LAPARREQAEELRADLAELAALRA 167

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1958764989 2081 ALKIQRSQLEKNLLEQKQENSCMQKEMATIELVAQDNHERARRLMKELRQMQQEYLELKKQ 2141
Cdd:COG4942    168 ELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEAL 228
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 1422-2138 1.62e-09

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 63.27  E-value: 1.62e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1422 EIECLEKTLLKRRSELREadrLLAEAESELACTKEKTKSAVEKFTDAKRNLLQTESDAEALEKRAQETALNLVKAEQQLR 1501
Cdd:pfam01576   58 EAEEMRARLAARKQELEE---ILHELESRLEEEEERSQQLQNEKKKMQQHIQDLEEQLDEEEAARQKLQLEKVTTEAKIK 134

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1502 LLQADAEDLEQHKIKQEEILKEINKVVAAKDADFQCLNEKKEKLTEELQSLQRDIKAAEVNEDHHLQVLKESESLLQAKR 1581
Cdd:pfam01576  135 KLEEDILLLEDQNSKLSKERKLLEERISEFTSNLAEEEEKAKSLSKLKNKHEAMISDLEERLKKEEKGRQELEKAKRKLE 214

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1582 AELETLKSQVTSQQQELAVLDSQLGHRREELLLLQDSLTQAKADLQEALTlgetEVAEKCSHIREVKSLLEELSFQKGEL 1661
Cdd:pfam01576  215 GESTDLQEQIAELQAQIAELRAQLAKKEEELQAALARLEEETAQKNNALK----KIRELEAQISELQEDLESERAARNKA 290

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1662 NVHISERRTQLTLIKQEIEKEEENLEVVLQQLSKHKTELKNVADILQLETN----ELQSLKLQHDQKVVELEKTQVDLLE 1737
Cdd:pfam01576  291 EKQRRDLGEELEALKTELEDTLDTTAAQQELRSKREQEVTELKKALEEETRsheaQLQEMRQKHTQALEELTEQLEQAKR 370

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1738 GKLELESLQQTAQQQRRELERQRQLLERDRRETERVR----AETQALQSCIECLNKEKEHLQEQCESWEKKSSHAKRVLA 1813
Cdd:pfam01576  371 NKANLEKAKQALESENAELQAELRTLQQAKQDSEHKRkkleGQLQELQARLSESERQRAELAEKLSKLQSELESVSSLLN 450

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1814 ATEESNNTEQSKLGQLEVSVRKLQQELELLSQDKLALHS-------DSAQEQQQLQDKREALNSLQKELENTQDHLNLAK 1886
Cdd:pfam01576  451 EAEGKNIKLSKDVSSLESQLQDTQELLQEETRQKLNLSTrlrqledERNSLQEQLEEEEEAKRNVERQLSTLQAQLSDMK 530

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1887 QDLMHTTKCQSALLSEQAQLQKDVSQWTARLESCQKETETKEQQLQELQDEIRESKLQLDQQEMVFQKLQK--------- 1957
Cdd:pfam01576  531 KKLEEDAGTLEALEEGKKRLQRELEALTQQLEEKAAAYDKLEKTKNRLQQELDDLLVDLDHQRQLVSNLEKkqkkfdqml 610

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1958 -----------------ERESEEQKLVASIVSLEQQQGQLERELMDQKSKLEWLLTD--VSAAEGRLRTLQKEERCTESL 2018
Cdd:pfam01576  611 aeekaisaryaeerdraEAEAREKETRALSLARALEEALEAKEELERTNKQLRAEMEdlVSSKDDVGKNVHELERSKRAL 690

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 2019 EKMLSQAKQQLSEREQQLMEKSGDLLALQKEADGMRADFSL---LRNQFLTERKKA-EKQVAGLKEALKIQRSQLEKNLL 2094
Cdd:pfam01576  691 EQQVEEMKTQLEELEDELQATEDAKLRLEVNMQALKAQFERdlqARDEQGEEKRRQlVKQVRELEAELEDERKQRAQAVA 770

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|....
gi 1958764989 2095 EQKQENSCMQKEMATIELVAQDNHERARRLMKELRQMQQEYLEL 2138
Cdd:pfam01576  771 AKKKLELDLKELEAQIDAANKGREEAVKQLKKLQAQMKDLQREL 814
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1417-2038 2.26e-09

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 62.73  E-value: 2.26e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1417 EDIVDEIECLEKTLLKRRSELREADRLLAEAESELACTKEKTKSAVEKFTDAKRNLLQTESDAEALEKRAQETALNLVKA 1496
Cdd:TIGR04523   36 KQLEKKLKTIKNELKNKEKELKNLDKNLNKDEEKINNSNNKIKILEQQIKDLNDKLKKNKDKINKLNSDLSKINSEIKND 115

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1497 EQQLRLLQADAEDLEQHKIKQEEILKEINKVVAAKDADFQCLNEKKEKLTEELQSLQ-----------------RDIKAA 1559
Cdd:TIGR04523  116 KEQKNKLEVELNKLEKQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQKEELEnelnllekeklniqkniDKIKNK 195

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1560 EVNEDHHLQVLKESES---LLQAKRAELE----TLKSQVTSQQQELAVLDSQLGHRREELLLLQDSLTQAKADLQEA--- 1629
Cdd:TIGR04523  196 LLKLELLLSNLKKKIQknkSLESQISELKkqnnQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKqke 275

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1630 LTLGETEVAEKCSHIREVKSLLEELSFQK-----GELNVHISERRTQLTLIKQEIEKEEENLEVVLQQLSKHKTELKNva 1704
Cdd:TIGR04523  276 LEQNNKKIKELEKQLNQLKSEISDLNNQKeqdwnKELKSELKNQEKKLEEIQNQISQNNKIISQLNEQISQLKKELTN-- 353

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1705 dilqlETNELQSLKLQHDQKVVELEKTQVDLLEGKLELESLQQTAQQQRRELERQRQLLERDRRETERVRAETQALQSCI 1784
Cdd:TIGR04523  354 -----SESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEI 428

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1785 ECLNKEKEHLQEQCESWEKKSSHAKRVLAATEESNNTEQSKLGQLEVSVRKLQQELEllsqdklalhsdsaQEQQQLQDK 1864
Cdd:TIGR04523  429 ERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQNLE--------------QKQKELKSK 494

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1865 REALNSL---QKELENTQDHLnlakqdlmhtTKCQSALLSEQAQLQKDVSQwtarlescqketetKEQQLQELQDEIRES 1941
Cdd:TIGR04523  495 EKELKKLneeKKELEEKVKDL----------TKKISSLKEKIEKLESEKKE--------------KESKISDLEDELNKD 550

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1942 KLQLDQQEMVFQKLQKERESEEQK-----LVASIVSLEQQQGQLERELMDQKSKLEWLLTDVSAAEGRLRTLQKEERCTE 2016
Cdd:TIGR04523  551 DFELKKENLEKEIDEKNKEIEELKqtqksLKKKQEEKQELIDQKEKEKKDLIKEIEEKEKKISSLEKELEKAKKENEKLS 630

                          650       660
                   ....*....|....*....|..
gi 1958764989 2017 SLEKMLSQAKQQLSEREQQLME 2038
Cdd:TIGR04523  631 SIIKNIKSKKNKLKQEVKQIKE 652
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 440-794 2.49e-09

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 62.73  E-value: 2.49e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  440 EDTGKQIVAAQTRLSELHHEIEAAEQKVLRATQEFKQLEEAIRQKKISEAEKDLLLKQlsgrlrhLNKLRQEALDLEAQL 519
Cdd:TIGR04523  162 NDLKKQKEELENELNLLEKEKLNIQKNIDKIKNKLLKLELLLSNLKKKIQKNKSLESQ-------ISELKKQNNQLKDNI 234

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  520 EKQRKEIAEKHEEINSAQlaTDLLDSKDpKQSHMKAQKRGKEQQLDIMNKQYTQLESRLDEILCRIATET---------- 589
Cdd:TIGR04523  235 EKKQQEINEKTTEISNTQ--TQLNQLKD-EQNKIKKQLSEKQKELEQNNKKIKELEKQLNQLKSEISDLNnqkeqdwnke 311

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  590 --EEIKDLEQQLTD--GQIAANEALKKDLEGVISGLQEYLG-------TIKGQAAQAQNECRKLQDEKETLLQRLTEVKQ 658
Cdd:TIGR04523  312 lkSELKNQEKKLEEiqNQISQNNKIISQLNEQISQLKKELTnsesensEKQRELEEKQNEIEKLKKENQSYKQEIKNLES 391

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  659 EKDELEIVAMDAENMRKELAELENALQEQHEVnasLQQAQGDLSAYETELETQLKLKDAETSQLKQELENLVRRTQLEQ- 737
Cdd:TIGR04523  392 QINDLESKIQNQEKLNQQKDEQIKKLQQEKEL---LEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLEt 468

                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1958764989  738 --SVLQTELEKERQSLRDalgKAQSSEEKQQENSELRAQLKQLQDDNSLLKKQLKDFQS 794
Cdd:TIGR04523  469 qlKVLSRSINKIKQNLEQ---KQKELKSKEKELKKLNEEKKELEEKVKDLTKKISSLKE 524
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 629-958 2.68e-09

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 62.78  E-value: 2.68e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  629 KGQAAQAQNECRKLQDEKETLLQRLTEVKQEKDELEIVAMDAENMRKEL-AELENALQEQHEVNASLQQAQGDLSAYE-- 705
Cdd:TIGR02169  673 PAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIeKEIEQLEQEEEKLKERLEELEEDLSSLEqe 752

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  706 --------TELETQLKLKDAETSQLKQELENLVRRtqLEQSVLQT------ELEKERQSLRDALGKAQSSEEKQQENSEL 771
Cdd:TIGR02169  753 ienvkselKELEARIEELEEDLHKLEEALNDLEAR--LSHSRIPEiqaelsKLEEEVSRIEARLREIEQKLNRLTLEKEY 830

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  772 RAQLKQ-LQDDNSLLKKQLKDFQSHLnhvvdglihpEEVAARVDELRKRLKLGAGEMRihspsdVLGKSLADLQKQFSEI 850
Cdd:TIGR02169  831 LEKEIQeLQEQRIDLKEQIKSIEKEI----------ENLNGKKEELEEELEELEAALR------DLESRLGDLKKERDEL 894

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  851 ---LARSQWEKEEAQVRERKLHEEMALQQEKLANGQEEFKQaceraLEARIKFDKR--QHNARIQQLENEIHYLQENLKS 925
Cdd:TIGR02169  895 eaqLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSE-----IEDPKGEDEEipEEELSLEDVQAELQRVEEEIRA 969

                          330       340       350
                   ....*....|....*....|....*....|...
gi 1958764989  926 MEKIQGLtdlqlqeADEEKERILAQLQELEKKK 958
Cdd:TIGR02169  970 LEPVNML-------AIQEYEEVLKRLDELKEKR 995
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 1322-2140 2.85e-09

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 62.68  E-value: 2.85e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1322 DLENEVSRLEDITHHLKSKHQEERWLKTSRQHPEKEVEELHRNIDDLvQEKKELELEVEELHRTVERHQQRRDFIDGNVE 1401
Cdd:pfam02463  230 DYLKLNEERIDLLQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKE-EEKEKKLQEEELKLLAKEEEELKSELLKLERR 308

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1402 NLMTELEIEKSLKHHEDIVDEIECLEKTLLKRRSELREADR-LLAEAESELACTKEKTKSAVEKFTDAKRNLLQTESDAE 1480
Cdd:pfam02463  309 KVDDEEKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIkREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSS 388

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1481 ALEKRAQETALNLVK---AEQQLRLLQADAEDLEQHKIKQEEILKEINKVVAAKDADFQCLNEKKEKLTEELQSLQRDIK 1557
Cdd:pfam02463  389 AAKLKEEELELKSEEekeAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELK 468

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1558 AAEVNEDHHLQVLKESESLLQAKRAELETLKSQVTSQQQELAVLDSqLGHRREELLLLQDSLTQAKADLQEALTLGETEV 1637
Cdd:pfam02463  469 KSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLA-LIKDGVGGRIISAHGRLGDLGVAVENYKVAIST 547

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1638 AEKCSHIREVKSLLEELSFQKGELNVHISERRTQLTLIKQeiekeeenlevvlqQLSKHKTELKNVADILQLETNELQSL 1717
Cdd:pfam02463  548 AVIVEVSATADEVEERQKLVRALTELPLGARKLRLLIPKL--------------KLPLKSIAVLEIDPILNLAQLDKATL 613

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1718 KLQHDQKVVELEKTQVDLLEGKLELESLQQTAQQQRRELERQRQLLERDRRETERvraetqalqsciecLNKEKEHLQEQ 1797
Cdd:pfam02463  614 EADEDDKRAKVVEGILKDTELTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASL--------------SELTKELLEIQ 679

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1798 CESWEKKSSHAKRVLAATEESNNTEQSKLGQLEvsvRKLQQELELLSQDKLALHSDSAQEQQQLQDKREALNSlqKELEN 1877
Cdd:pfam02463  680 ELQEKAESELAKEEILRRQLEIKKKEQREKEEL---KKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEE--EEEEK 754

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1878 TQDHLNLAKQDLMHTTKCQSALLSEQAQLQKDVSQWTARLESCQKETETKEQQLQELQDEIRESKLQLDQQemvfQKLQK 1957
Cdd:pfam02463  755 SRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIE----QEEKI 830

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1958 ERESEEQKLVASIVSLEQQQGQLERELMDQKSKLEWLLTDVSAAEGRLRTLQKEERCTESLEKMLSQAKQQLSEREQQLM 2037
Cdd:pfam02463  831 KEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLN 910

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 2038 EksgdLLALQKEADGMRADFSLLRNQFLTERKKAEKQVAGLKEALKIQRSQLEKNLLEQKQENSCMQKEMATIELVAQDN 2117
Cdd:pfam02463  911 L----LEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKEKEENNKEEEEERNKRLLLAKEELGKVNLMAIEEFEEK 986

                          810       820
                   ....*....|....*....|...
gi 1958764989 2118 HERARRLMKELRQMQQEYLELKK 2140
Cdd:pfam02463  987 EERYNKDELEKERLEEEKKKLIR 1009
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 590-959 3.29e-09

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 62.39  E-value: 3.29e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  590 EEIKDLEQQLTDGQIAANEalkkdLEGVISGLQEYLGTIKGQAAQAQNECRKLQDEKETLLQRLTEVKQEKDELEivaMD 669
Cdd:TIGR02169  681 ERLEGLKRELSSLQSELRR-----IENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLE---QE 752

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  670 AENMRKELAELENALQEQHEVNASLQQAQGDLsaYETELETQLKLKDAETSQLKQELENLVRRTQLEQSVLQtELEKERQ 749
Cdd:TIGR02169  753 IENVKSELKELEARIEELEEDLHKLEEALNDL--EARLSHSRIPEIQAELSKLEEEVSRIEARLREIEQKLN-RLTLEKE 829

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  750 SLRDalgkaqSSEEKQQENSELRAQLKQLQDDNSLLKKQLKDFQSHLnhvvdglihpEEVAARVDELRKRLKLGAGEMRi 829
Cdd:TIGR02169  830 YLEK------EIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEEL----------EELEAALRDLESRLGDLKKERD- 892

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  830 hspsdvlgkslaDLQKQFSEIlarsQWEKEEAQVRERKLHEEMALQQEKLANGQEEFKQaceraLEARIKFDK------- 902
Cdd:TIGR02169  893 ------------ELEAQLREL----ERKIEELEAQIEKKRKRLSELKAKLEALEEELSE-----IEDPKGEDEeipeeel 951

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1958764989  903 --RQHNARIQQLENEIHYLQE-NLKSMEK----IQGLTDLQLQEA--DEEKERILAQLQELEKKKR 959
Cdd:TIGR02169  952 slEDVQAELQRVEEEIRALEPvNMLAIQEyeevLKRLDELKEKRAklEEERKAILERIEEYEKKKR 1017
PTZ00121 PTZ00121
MAEBL; Provisional
 452-1092 3.38e-09

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 62.47  E-value: 3.38e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  452 RLSELHHEIEAAEQKVLRATQEFKQLEEAIR---QKKISEAEKDLLLKQLSgRLRHLNKLRQEALDLEAQLEKQRKEIAE 528
Cdd:PTZ00121  1177 KAEAARKAEEVRKAEELRKAEDARKAEAARKaeeERKAEEARKAEDAKKAE-AVKKAEEAKKDAEEAKKAEEERNNEEIR 1255

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  529 KHEEINSAQLATDLLDSKdpKQSHMKAQKRGKEQQLDIMNKQYTQLESRLDEILCRIATETEEIKDLEQQLTDGQIAANE 608
Cdd:PTZ00121  1256 KFEEARMAHFARRQAAIK--AEEARKADELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADA 1333

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  609 ALKKDLEGvisglQEYLGTIKGQAAQAQNECRKLQDEKETLLQRLTEVKQEKDELEIVAMD----------AENMRKELA 678
Cdd:PTZ00121  1334 AKKKAEEA-----KKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEkkkadeakkkAEEDKKKAD 1408

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  679 ELENALQEQHEVNASLQQAQGDLSAYETELETQLKLKDAET---SQLKQELENLVRRTqlEQSVLQTELEKERQSLRDAL 755
Cdd:PTZ00121  1409 ELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAkkkAEEAKKAEEAKKKA--EEAKKADEAKKKAEEAKKAD 1486

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  756 GKAQSSEEKQQENSELRAQLKQLQDDNSLLKKQLKDFQSHLNHV-----VDGLIHPEEVAaRVDELRKRLKL-------G 823
Cdd:PTZ00121  1487 EAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAeeakkADEAKKAEEKK-KADELKKAEELkkaeekkK 1565

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  824 AGEMRIHSPSDVLGKSLADLQKQFSE----ILARSQWEKEEAQVRERKLHEEMALQQEKLANGQEEfKQACERALEARIK 899
Cdd:PTZ00121  1566 AEEAKKAEEDKNMALRKAEEAKKAEEarieEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEE-KKKVEQLKKKEAE 1644

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  900 FDKRQHNARIQQLENEIHYLQENLKSMEKIQGLTDLQLQEADEEKERILAQLQELEKKKRREDARSQEQFLGLDTELK-- 977
Cdd:PTZ00121  1645 EKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKka 1724

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  978 -SLKKAVAASDKLAAAELTIAKEQLKSLHGTVMRINQERAEELQEAERSSREAMQAAKDLSRAEAEIELLqhllrEREGQ 1056
Cdd:PTZ00121  1725 eEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRM-----EVDKK 1799

                          650       660       670
                   ....*....|....*....|....*....|....*.
gi 1958764989 1057 FRDEMENAHVGSKGANLQLLEIEALKEAMAKQRAEI 1092
Cdd:PTZ00121  1800 IKDIFDNFANIIEGGKEGNLVINDSKEMEDSAIKEV 1835
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1581-2141 4.62e-09

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 62.00  E-value: 4.62e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1581 RAELETLKSQVtSQQQELAVLDSQLGHRREELLLLQ-DSLTQAKADLQEALTLGETEVAEKCSHIREVKSLLEELSFQKG 1659
Cdd:TIGR02168  199 ERQLKSLERQA-EKAERYKELKAELRELELALLVLRlEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVS 277

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1660 ELNVHISERRTQLTLIKQEIEKEEENLEVVLQQLSKHKTELKNVADILQLETNELQSLKLQHDQKVVELE--KTQVDLLE 1737
Cdd:TIGR02168  278 ELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEelKEELESLE 357

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1738 GKL-ELESLQQTAQQQRRELERQRQLLERDRRETER----VRAETQALQSCIECLNKEKEHLQEQCESWEKKSSHAKrvL 1812
Cdd:TIGR02168  358 AELeELEAELEELESRLEELEEQLETLRSKVAQLELqiasLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAE--L 435

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1813 AATEESNNTEQSKLGQLEVSVRKLQQELELLSQDKLALHSDSAQEQQQLQDKREALNSLQKELENTQDHLNLAKQDLMHT 1892
Cdd:TIGR02168  436 KELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQ 515

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1893 --------------------TKCQSALLSE--QAQLQKDVSQWTARLEScQKETETKEQQLQELQD----EIRESKLQLD 1946
Cdd:TIGR02168  516 sglsgilgvlselisvdegyEAAIEAALGGrlQAVVVENLNAAKKAIAF-LKQNELGRVTFLPLDSikgtEIQGNDREIL 594

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1947 QQEMVFQKLQKERESEEQKL-------------VASIVSLEQQQGQLERELM-----DQKSKLEWLLT--DVSAAEGRLR 2006
Cdd:TIGR02168  595 KNIEGFLGVAKDLVKFDPKLrkalsyllggvlvVDDLDNALELAKKLRPGYRivtldGDLVRPGGVITggSAKTNSSILE 674

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 2007 TLQKEERCTESLEKMLSQA---KQQLSEREQQLMEKSGDLLALQKEADGMRADFSLLRNQFLTERKKAEkQVAGLKEALK 2083
Cdd:TIGR02168  675 RRREIEELEEKIEELEEKIaelEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVE-QLEERIAQLS 753

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1958764989 2084 IQRSQLEKNLLEQKQENSCMQKEMATIELVAQDNHERARRLMKELRQMQQEYLELKKQ 2141
Cdd:TIGR02168  754 KELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAE 811
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
631-1060 5.25e-09

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 61.32  E-value: 5.25e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  631 QAAQAQNECRKLQDEKETLLQRLTEVKQEKDELEIVAMDAENMRKELAELENALQeQHEVNASLQQAQGDLSAYETELEt 710
Cdd:COG4717     72 ELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQ-LLPLYQELEALEAELAELPERLE- 149

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  711 QLKLKDAETSQLKQELENLVRRTQLEQSVLQTELEKERQSLRDALGKAQSS-EEKQQENSELRAQLKQLQDDNSLLKKQL 789
Cdd:COG4717    150 ELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEElEELQQRLAELEEELEEAQEELEELEEEL 229

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  790 KDFQSHLNHvvdglihpEEVAARVDELRKRLKLGAGEMRIHSPSDVLGKSLADLQK----------QFSEILARSQWEKE 859
Cdd:COG4717    230 EQLENELEA--------AALEERLKEARLLLLIAAALLALLGLGGSLLSLILTIAGvlflvlgllaLLFLLLAREKASLG 301

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  860 EAQVRERKLHEEMALQQEKLANGQEEFKqaCERALEARIKFDKRQHNARIQQLENEIHYLQENLK---SMEKIQGLTDLQ 936
Cdd:COG4717    302 KEAEELQALPALEELEEEELEELLAALG--LPPDLSPEELLELLDRIEELQELLREAEELEEELQleeLEQEIAALLAEA 379

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  937 LQEADEEKERILAQLQEL-EKKKRREDARSQ-EQFLGLDTELKSLKKAVAASDKLA--AAELTIAKEQLKSLHGTVMRIN 1012
Cdd:COG4717    380 GVEDEEELRAALEQAEEYqELKEELEELEEQlEELLGELEELLEALDEEELEEELEelEEELEELEEELEELREELAELE 459

                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1958764989 1013 Q-----ERAEELQEAERSSREAMQAAKDLSRAEAEIELLQHLLREREGQFRDE 1060
Cdd:COG4717    460 AeleqlEEDGELAELLQELEELKAELRELAEEWAALKLALELLEEAREEYREE 512
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1396-1967 6.49e-09

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 61.29  E-value: 6.49e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1396 IDGNVENLMTELEIEKSLKHhedivDEIECLEKTLLKRRSELREA------------------DRLLAE---AESELACT 1454
Cdd:pfam15921  322 LESTVSQLRSELREAKRMYE-----DKIEELEKQLVLANSELTEArterdqfsqesgnlddqlQKLLADlhkREKELSLE 396

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1455 KEKTKSAVEKFTDAKRNL--LQTESDAEALEKRAQETALNLVKAE------QQLRLLQADAEDLEQhkikqeeilkeink 1526
Cdd:pfam15921  397 KEQNKRLWDRDTGNSITIdhLRRELDDRNMEVQRLEALLKAMKSEcqgqmeRQMAAIQGKNESLEK-------------- 462

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1527 vVAAKDADFQCLNEKKEKLTEELQSLQRDIKAAEVNEDHHLQVLKESESLLQAKRAELETLKSQVTSQQQELAVLDSQLG 1606
Cdd:pfam15921  463 -VSSLTAQLESTKEMLRKVVEELTAKKMTLESSERTVSDLTASLQEKERAIEATNAEITKLRSRVDLKLQELQHLKNEGD 541

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1607 HrreelllLQDSLTQAkadlqEALTLGETEVAEKCSHIREVKSLLEELSFQKGELNVHISERRTQLTlikqeiekeeenl 1686
Cdd:pfam15921  542 H-------LRNVQTEC-----EALKLQMAEKDKVIEILRQQIENMTQLVGQHGRTAGAMQVEKAQLE------------- 596

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1687 evvlqqlskhktelKNVADiLQLETNELQSLKLQHDQKVVELEKTQVDLlegKLELESLQQTAQQQRRELERQRQLLERD 1766
Cdd:pfam15921  597 --------------KEIND-RRLELQEFKILKDKKDAKIRELEARVSDL---ELEKVKLVNAGSERLRAVKDIKQERDQL 658

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1767 RRETERVRAETQALQSCIECLnkeKEHLQEQCESWEKKSSHAKRVLaateesnNTEQSKLGQLEVSVRKLQqelellSQD 1846
Cdd:pfam15921  659 LNEVKTSRNELNSLSEDYEVL---KRNFRNKSEEMETTTNKLKMQL-------KSAQSELEQTRNTLKSME------GSD 722

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1847 KLALHSdSAQEQQQLQDKREALNSLQKELENTQDHLNLAKQDlmhttkcQSALLSEQAQLQKDVSQWTARLESCQKETET 1926
Cdd:pfam15921  723 GHAMKV-AMGMQKQITAKRGQIDALQSKIQFLEEAMTNANKE-------KHFLKEEKNKLSQELSTVATEKNKMAGELEV 794

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|.
gi 1958764989 1927 KEQQLQELQDEIRESKLQLDQQEMVFQKLQKERESEEQKLV 1967
Cdd:pfam15921  795 LRSQERRLKEKVANMEVALDKASLQFAECQDIIQRQEQESV 835
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1512-2141 6.95e-09

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 61.19  E-value: 6.95e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1512 QHKIKQEE-ILKEINKVVAAKDADFQCLNEKkeklTEELQSLQRDIKAAEVNEDHHLQVLKESESLLQAkraELETLKSQ 1590
Cdd:TIGR04523   46 KNELKNKEkELKNLDKNLNKDEEKINNSNNK----IKILEQQIKDLNDKLKKNKDKINKLNSDLSKINS---EIKNDKEQ 118

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1591 VTSQQQELAVLDSQLGHRREELLLLQDSLTQAkadlqealtlgETEVAEKCSHIREVKSLLEELSFQKGELNVHISERRT 1670
Cdd:TIGR04523  119 KNKLEVELNKLEKQKKENKKNIDKFLTEIKKK-----------EKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQK 187

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1671 QLTLIKQEIEKEEENLEVVLQQLSKHKTelknvadiLQLETNELQS----LKLQHDQKVVELEKTQVDLLEGKLELESLQ 1746
Cdd:TIGR04523  188 NIDKIKNKLLKLELLLSNLKKKIQKNKS--------LESQISELKKqnnqLKDNIEKKQQEINEKTTEISNTQTQLNQLK 259

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1747 QTAQQQRRELERQRQLLERDRRETERVRAETQALQSCIECLNKEKEhlqeqcESWEKKsshAKRVLAATEESNNTEQSKL 1826
Cdd:TIGR04523  260 DEQNKIKKQLSEKQKELEQNNKKIKELEKQLNQLKSEISDLNNQKE------QDWNKE---LKSELKNQEKKLEEIQNQI 330

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1827 GQLEVSVRKLQQELELLSQDKLALHSDSAQEQQQLQDKREALNSLQKELENTqdhlnlaKQDLMHTTKCQSALLSEQAQL 1906
Cdd:TIGR04523  331 SQNNKIISQLNEQISQLKKELTNSESENSEKQRELEEKQNEIEKLKKENQSY-------KQEIKNLESQINDLESKIQNQ 403

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1907 QKDVSQWTARLESCQKETETKEQQLQEL-------QDEIRESKLQLDQQEMVFQKLQKERESEEQKLVA---SIVSLEQQ 1976
Cdd:TIGR04523  404 EKLNQQKDEQIKKLQQEKELLEKEIERLketiiknNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVlsrSINKIKQN 483

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1977 QGQLERELMDQKSKLEWLLTDVSAAEGRLRTLQKEERCTESLEKMLSQAKqqlSEREQQLMEKSGDLLALQKEADgmrad 2056
Cdd:TIGR04523  484 LEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLESEK---KEKESKISDLEDELNKDDFELK----- 555

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 2057 fsllrnqflterkkaekqvaglKEALKIQRSQLEKNLLEQKQENSCMQKEMATIELVAQDNHERARRLMKELRQMQQEYL 2136
Cdd:TIGR04523  556 ----------------------KENLEKEIDEKNKEIEELKQTQKSLKKKQEEKQELIDQKEKEKKDLIKEIEEKEKKIS 613


                   ....*
gi 1958764989 2137 ELKKQ 2141
Cdd:TIGR04523  614 SLEKE 618
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
577-1096 7.22e-09

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 61.47  E-value: 7.22e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  577 RLDEILCRIATETEEIKDLEQQLTDGQ-IAANEALKKDLEGVISGLQEY-----LGTIKGQAAQAQNECRKLQDEKETLL 650
Cdd:COG4913    236 DLERAHEALEDAREQIELLEPIRELAErYAAARERLAELEYLRAALRLWfaqrrLELLEAELEELRAELARLEAELERLE 315

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  651 QRLTEVKQEKDELEIVAMDAENMRKELAElenalQEQHEVNASLQQAQGDLSAYETELEtQLKLKDAETsqlKQELENLV 730
Cdd:COG4913    316 ARLDALREELDELEAQIRGNGGDRLEQLE-----REIERLERELEERERRRARLEALLA-ALGLPLPAS---AEEFAALR 386

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  731 RRTQLeqsvLQTELEKERQSLRDALGKAQSSEEKQQEN-SELRAQLKQLQDDNSLLKKQLKDFQSHLNHV---------- 799
Cdd:COG4913    387 AEAAA----LLEALEEELEALEEALAEAEAALRDLRRElRELEAEIASLERRKSNIPARLLALRDALAEAlgldeaelpf 462

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  800 -----------------VDGLIHP------------EEVAARVDELRKRLKLGAGEMRIHSPSDVLGKSLAD-------- 842
Cdd:COG4913    463 vgelievrpeeerwrgaIERVLGGfaltllvppehyAAALRWVNRLHLRGRLVYERVRTGLPDPERPRLDPDslagkldf 542

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  843 ------------LQKQFSEILARSQWE--------KEEAQVRERKLHEEMALQQEKLAN---GQE-----EFKQACERAL 894
Cdd:COG4913    543 kphpfrawleaeLGRRFDYVCVDSPEElrrhpraiTRAGQVKGNGTRHEKDDRRRIRSRyvlGFDnraklAALEAELAEL 622

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  895 EARIkfdkRQHNARIQQLENEIHYLQENLKSMEKIQgltdlQLQEADEEKERILAQLQELEKKKRREDARSQeqflgldt 974
Cdd:COG4913    623 EEEL----AEAEERLEALEAELDALQERREALQRLA-----EYSWDEIDVASAEREIAELEAELERLDASSD-------- 685

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  975 ELKSLKKAVAAsdklAAAELTIAKEQLKSLHGTVMRINQERA---EELQEAERSSREAMQAAKDLSRAEAEIELLQHLLR 1051
Cdd:COG4913    686 DLAALEEQLEE----LEAELEELEEELDELKGEIGRLEKELEqaeEELDELQDRLEAAEDLARLELRALLEERFAAALGD 761

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|....*
gi 1958764989 1052 EREGQFRDEMENahvgskganlqllEIEALKEAMAKQRAEITRLR 1096
Cdd:COG4913    762 AVERELRENLEE-------------RIDALRARLNRAEEELERAM 793
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 510-757 7.99e-09

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 60.16  E-value: 7.99e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  510 QEALDLEAQLEKQRKEIAEKHEEINSAQlatdlldskdpkqshmkAQKRGKEQQLDIMNKQYTQLESRLDEILCRIATET 589
Cdd:COG4942     20 DAAAEAEAELEQLQQEIAELEKELAALK-----------------KEEKALLKQLAALERRIAALARRIRALEQELAALE 82

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  590 EEIKDLEQQLTDGQiAANEALKKDLEGVI-----SGLQEYLGTIKGQ--AAQAQNECRKLQDEKETLLQRLTEVKQEKDE 662
Cdd:COG4942     83 AELAELEKEIAELR-AELEAQKEELAELLralyrLGRQPPLALLLSPedFLDAVRRLQYLKYLAPARREQAEELRADLAE 161

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  663 LEIVAMDAENMRKELAELENALQEQHEVNASLQQAQGDLSAyetELETQLKLKDAETSQLKQELENLVRR-TQLEQSVLQ 741
Cdd:COG4942    162 LAALRAELEAERAELEALLAELEEERAALEALKAERQKLLA---RLEKELAELAAELAELQQEAEELEALiARLEAEAAA 238

                          250
                   ....*....|....*.
gi 1958764989  742 TELEKERQSLRDALGK 757
Cdd:COG4942    239 AAERTPAAGFAALKGK 254
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 436-753 9.05e-09

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 60.85  E-value: 9.05e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  436 DVQLEDTGKQIVAAQTRLSELHHEIEAAEQKVLRATQEFKQLEEAIRQKKISEAEKDLLLKQLSgrlRHLNKLRQEALDL 515
Cdd:TIGR02169  687 KRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLE---QEIENVKSELKEL 763

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  516 EAQLEKQRKEIAEKHEEINSaqLATDLLDSKDPKqshMKAQKRGKEQQLDIMNKQYTQLESRLDEILCRIATETEEIKDL 595
Cdd:TIGR02169  764 EARIEELEEDLHKLEEALND--LEARLSHSRIPE---IQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQEL 838

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  596 EQQL--TDGQIAANEALKKDLEGVISGLQEYLGTIKGQAAQAQNECRKLQDEKETLLQRLTEVKQEKDELEIvamDAENM 673
Cdd:TIGR02169  839 QEQRidLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEA---QIEKK 915

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  674 RKELAELENALQEQHEVNASLQQAQGDLSAYETELETQLKLKdAETSQLKQELENL-------------VRRTQLEQSVL 740
Cdd:TIGR02169  916 RKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEELSLEDVQ-AELQRVEEEIRALepvnmlaiqeyeeVLKRLDELKEK 994

                          330
                   ....*....|...
gi 1958764989  741 QTELEKERQSLRD 753
Cdd:TIGR02169  995 RAKLEEERKAILE 1007
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 1538-2106 9.81e-09

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 60.89  E-value: 9.81e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1538 LNEKKEKLTEELQSLQRDIKAAEVNEDHHLQVLKESESLLQAKRAELETLKSQVTSQQQELAVLDSQLGHRREELLLLQD 1617
Cdd:pfam05483  217 LKEDHEKIQHLEEEYKKEINDKEKQVSLLLIQITEKENKMKDLTFLLEESRDKANQLEEKTKLQDENLKELIEKKDHLTK 296

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1618 SLTQAKADLQEALTLGETEVAEKCSHIREVKSLLEELSFQKGELNVHISERRTQLTLIKQEIEKEEENLEVVLQQLSKHK 1697
Cdd:pfam05483  297 ELEDIKMSLQRSMSTQKALEEDLQIATKTICQLTEEKEAQMEELNKAKAAHSFVVTEFEATTCSLEELLRTEQQRLEKNE 376

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1698 TELKNVADILQLETNELQSLKLQHDQKVVELEKTQV------DLLEGKLELESLQQTAQQQRRELErqrQLLERDRRETE 1771
Cdd:pfam05483  377 DQLKIITMELQKKSSELEEMTKFKNNKEVELEELKKilaedeKLLDEKKQFEKIAEELKGKEQELI---FLLQAREKEIH 453

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1772 RVRAETQALQSCIECLNKEKEHLQEQCEswekksshaKRVLAATEESNNTEQSKLGQLEVSVRKLQQELELLSQDKLALH 1851
Cdd:pfam05483  454 DLEIQLTAIKTSEEHYLKEVEDLKTELE---------KEKLKNIELTAHCDKLLLENKELTQEASDMTLELKKHQEDIIN 524

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1852 SDSAQEQ--QQLQDKREALNSLQKELENTQDHL----NLAKQDLMHTTKCQSALLSEQAQLQKDVSQWTARLESCQKETE 1925
Cdd:pfam05483  525 CKKQEERmlKQIENLEEKEMNLRDELESVREEFiqkgDEVKCKLDKSEENARSIEYEVLKKEKQMKILENKCNNLKKQIE 604

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1926 TKEQQLQELQDEIRESK-------LQLDQQEMVFQKLQKERESEEQKlvasivsLEQQQGQLERELMDQKSKLEWLLTDV 1998
Cdd:pfam05483  605 NKNKNIEELHQENKALKkkgsaenKQLNAYEIKVNKLELELASAKQK-------FEEIIDNYQKEIEDKKISEEKLLEEV 677

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1999 SAAEGRLR---TLQKE--ERCTESLEKMLSQAKQQLSEREQQLMEKSGDL-LALQKEADGmradfSLLRNQFLTERKKAE 2072
Cdd:pfam05483  678 EKAKAIADeavKLQKEidKRCQHKIAEMVALMEKHKHQYDKIIEERDSELgLYKNKEQEQ-----SSAKAALEIELSNIK 752

                          570       580       590
                   ....*....|....*....|....*....|....
gi 1958764989 2073 KQVAGLKEALKIQRSQLEKnLLEQKQENSCMQKE 2106
Cdd:pfam05483  753 AELLSLKKQLEIEKEEKEK-LKMEAKENTAILKD 785
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 444-662 1.06e-08

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 59.78  E-value: 1.06e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  444 KQIVAAQTRLSELHHEIEAAEQKVLRATQEFKQLEEAIRQ--KKISEAEKDL--LLKQLSGRLRHLNKLRQEALDLEAQL 519
Cdd:COG4942     20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAAleRRIAALARRIraLEQELAALEAELAELEKEIAELRAEL 99

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  520 EKQRKEIAE------KHEEINSAQLatdLLDSKDPKQSHMKAQKRGkeQQLDIMNKQYTQLESRLDEILCRIATETEEIK 593
Cdd:COG4942    100 EAQKEELAEllralyRLGRQPPLAL---LLSPEDFLDAVRRLQYLK--YLAPARREQAEELRADLAELAALRAELEAERA 174

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1958764989  594 DLEQQLtdgqiAANEALKKDLEGVISGLQEYLGTIKGQAAQAQNECRKLQDEKETLLQRLTEVKQEKDE 662
Cdd:COG4942    175 ELEALL-----AELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAA 238
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 259-1002 1.07e-08

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 60.85  E-value: 1.07e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  259 DRQEAFERFSLEEIERLEKDLEKKtvetEELKNKQTKfLEEIKHQDKLNKSLKEEAMLqkqscEELESDLNTKKELLKQK 338
Cdd:TIGR02169  187 ERLDLIIDEKRQQLERLRREREKA----ERYQALLKE-KREYEGYELLKEKEALERQK-----EAIERQLASLEEELEKL 256

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  339 TVELTRACQKQYELEQELAfyKIDAKFEPLNyypSEYAEMDKSPDESPYIGKSRYKRNMFATETYIVSDAQAVQVRKMVP 418
Cdd:TIGR02169  257 TEEISELEKRLEEIEQLLE--ELNKKIKDLG---EEEQLRVKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEI 331

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  419 DGGQLRHEHAPRAQAPPDVQLEDTGKQIVAAQTRLSELHHEIEAAEQKVLRATQEFKQLEEAIRQKKiseAEKDLLLKQL 498
Cdd:TIGR02169  332 DKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLK---REINELKREL 408

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  499 SGRLRHLNKLRQEALDLEAQLEKQRKEIAEKHEEINSAQL----ATDLLDSKDPKQSHMKAQKRGKEQQLDIMNKQYTQL 574
Cdd:TIGR02169  409 DRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALeikkQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKL 488

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  575 ESRLDEILCRIATETEEIKdleqqltdGQIAANEALKKDLEGVIsGLQEYLGTIKGQ----------------------- 631
Cdd:TIGR02169  489 QRELAEAEAQARASEERVR--------GGRAVEEVLKASIQGVH-GTVAQLGSVGERyataievaagnrlnnvvveddav 559

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  632 AAQAQNECRKLQDEKETLLQrLTEVKQEKDELEIVAMD-----AENMRKELAELENA---------------LQEQHEVN 691
Cdd:TIGR02169  560 AKEAIELLKRRKAGRATFLP-LNKMRDERRDLSILSEDgvigfAVDLVEFDPKYEPAfkyvfgdtlvvedieAARRLMGK 638

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  692 ASLQQAQGDL-------------SAYETELETQLKLKDAETSQLKQELENLVRRTQLEQSVLQTELEKERQSLRDAlgka 758
Cdd:TIGR02169  639 YRMVTLEGELfeksgamtggsraPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDA---- 714

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  759 qsseekQQENSELRAQLKQLQDDNSLLKKQLKDFQSHLNHVVDGLIHPE----EVAARVDELRK-----RLKLGAGEMRI 829
Cdd:TIGR02169  715 ------SRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKselkELEARIEELEEdlhklEEALNDLEARL 788

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  830 -HSPSDVLGKSLADLQKQFSEILARSQwekeEAQVRERKLHEEMALQQEKLANGQE-----EFKQACERALEARIKFDKR 903
Cdd:TIGR02169  789 sHSRIPEIQAELSKLEEEVSRIEARLR----EIEQKLNRLTLEKEYLEKEIQELQEqridlKEQIKSIEKEIENLNGKKE 864

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  904 QHNARIQQLENEIHYLQENLKSMEKIQGLTDLQLQEADEEKERILAQLQELEKKKRREDARSQEQFlgldTELKSLKKAV 983
Cdd:TIGR02169  865 ELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALE----EELSEIEDPK 940

                          810
                   ....*....|....*....
gi 1958764989  984 AASDKLAAAELTIAKEQLK 1002
Cdd:TIGR02169  941 GEDEEIPEEELSLEDVQAE 959
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 535-769 1.50e-08

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 59.01  E-value: 1.50e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  535 SAQLATDLLDSKDPKQSHMKAQKRGKEQQLDIMNKQYTQLESRLDEILCRIATETEEIKDLEQQL--TDGQIAANEALKK 612
Cdd:COG4942     14 AAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELaaLEAELAELEKEIA 93

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  613 DLEGVISGLQEYLgtikgqAAQAQNECRKLQDEKETLLQRLTEVKQEKDELEIVAMDAENMRKELAELENALQEQHEVNA 692
Cdd:COG4942     94 ELRAELEAQKEEL------AELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRA 167

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1958764989  693 SLQQAQGDLSAYETELETQLKLKDAETSQLKQELENLVRRTQLEQSVLQtELEKERQSLRDALGKAQSSEEKQQENS 769
Cdd:COG4942    168 ELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELA-ELQQEAEELEALIARLEAEAAAAAERT 243
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1355-1998 1.68e-08

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 60.05  E-value: 1.68e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1355 EKEVEELHRNIDDLVQEKKELELEVEELHRTVERHQQRRDfidgnvenlmtelEIEKSLKHHEDIVDEIECLEKTLLKRR 1434
Cdd:PRK02224   198 EKEEKDLHERLNGLESELAELDEEIERYEEQREQARETRD-------------EADEVLEEHEERREELETLEAEIEDLR 264

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1435 SELREADRLLAEAESELACTKEKTKSAVEKFTDAKRNLLQTESDAEALEKRAQEtalnLVKAEQQLRllqadaEDLEQHK 1514
Cdd:PRK02224   265 ETIAETEREREELAEEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREE----LEDRDEELR------DRLEECR 334

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1515 IKQEEILKEINKvvAAKDADfqCLNEKKEKLTEELQSLQRDIKAAEVNedhhlqvLKESESLLQAKRAELETLKSQVTSQ 1594
Cdd:PRK02224   335 VAAQAHNEEAES--LREDAD--DLEERAEELREEAAELESELEEAREA-------VEDRREEIEELEEEIEELRERFGDA 403

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1595 QQELAVLDSQLGHRREELLLLQDSLTQAKADLQEALtlgetevaekcSHIREVKSLLEELSFQKGELNVHISERRTQLTL 1674
Cdd:PRK02224   404 PVDLGNAEDFLEELREERDELREREAELEATLRTAR-----------ERVEEAEALLEAGKCPECGQPVEGSPHVETIEE 472

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1675 IKqeiekeeenlevvlQQLSKHKTELKNVadilqletnelqslklqhdqkvveleKTQVDLLEGKLE-LESLQQTAQQQR 1753
Cdd:PRK02224   473 DR--------------ERVEELEAELEDL--------------------------EEEVEEVEERLErAEDLVEAEDRIE 512

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1754 ReLERQRQLLErDRRETERVRAETQALQscIECLNKEKEHLQEQCESWEKKSSHAkrvlaatEESNNTEQSKLGQLEVSV 1833
Cdd:PRK02224   513 R-LEERREDLE-ELIAERRETIEEKRER--AEELRERAAELEAEAEEKREAAAEA-------EEEAEEAREEVAELNSKL 581

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1834 RKLQQELELLS--QDKLALHSDSAQEQQQLQDKREALNSLQKELENTQDHLNLAKQDLmhTTKCQSALLSEqaqLQKDVS 1911
Cdd:PRK02224   582 AELKERIESLEriRTLLAAIADAEDEIERLREKREALAELNDERRERLAEKRERKREL--EAEFDEARIEE---AREDKE 656

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1912 QWTARLESCQKETETKEQQLQELQDEIRESKLQLDQQEmvfqKLQKERESEEQKLVA------SIVSLEQQQGQLERELM 1985
Cdd:PRK02224   657 RAEEYLEQVEEKLDELREERDDLQAEIGAVENELEELE----ELRERREALENRVEAlealydEAEELESMYGDLRAELR 732

                          650
                   ....*....|....
gi 1958764989 1986 DQK-SKLEWLLTDV 1998
Cdd:PRK02224   733 QRNvETLERMLNET 746
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 1338-2141 1.79e-08

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 60.06  E-value: 1.79e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1338 KSKHQEERWLKTSRQHPEKEVEELHRNIDDLVQEKKELELEVEELHRTVERHQQRRDFIDgNVENLMTELEIEKSLKHHE 1417
Cdd:TIGR00606  216 KEKACEIRDQITSKEAQLESSREIVKSYENELDPLKNRLKEIEHNLSKIMKLDNEIKALK-SRKKQMEKDNSELELKMEK 294

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1418 DIVDEIECLEKTLLKRRSELREADRLLAEAESELactkEKTKSAVEKFTDAKRNLLQTESDAEALEKRAQETALNLVKAE 1497
Cdd:TIGR00606  295 VFQGTDEQLNDLYHNHQRTVREKERELVDCQREL----EKLNKERRLLNQEKTELLVEQGRLQLQADRHQEHIRARDSLI 370

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1498 QQLRlLQADAEDLEQHKIKQEEILKEINKVVAAKDADFQCLNEKKEKLTEELQSLQRDIKAAEVNEDHHLQVLKESESLL 1577
Cdd:TIGR00606  371 QSLA-TRLELDGFERGPFSERQIKNFHTLVIERQEDEAKTAAQLCADLQSKERLKQEQADEIRDEKKGLGRTIELKKEIL 449

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1578 QAKRAELETLKS---QVTSQQQELAVLDSQLGHRREELLLLQD------------SLTQAKADLQEALTLGETEVAEKcS 1642
Cdd:TIGR00606  450 EKKQEELKFVIKelqQLEGSSDRILELDQELRKAERELSKAEKnsltetlkkevkSLQNEKADLDRKLRKLDQEMEQL-N 528

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1643 HIREVKSLLEELSFQKGELNVHISERRTQLTLIKQEIEKEEENLEVVLQQLSKHKTELKNVADILQLETNELQSLKLQHD 1722
Cdd:TIGR00606  529 HHTTTRTQMEMLTKDKMDKDEQIRKIKSRHSDELTSLLGYFPNKKQLEDWLHSKSKEINQTRDRLAKLNKELASLEQNKN 608

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1723 QKVVELEKTQVDLLEGKLELESLqQTAQQQRRELERQRQLLERDRRETERVRAETQALQSCIECLNKEKEHLQEQCESWE 1802
Cdd:TIGR00606  609 HINNELESKEEQLSSYEDKLFDV-CGSQDEESDLERLKEEIEKSSKQRAMLAGATAVYSQFITQLTDENQSCCPVCQRVF 687

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1803 KKSSHAKRVLAATEESNNTEQSKLGQLEVSVRKLQQELELLSQDKLALHSDSAQEQQQLQDKREALNSLQKELENTQDhl 1882
Cdd:TIGR00606  688 QTEAELQEFISDLQSKLRLAPDKLKSTESELKKKEKRRDEMLGLAPGRQSIIDLKEKEIPELRNKLQKVNRDIQRLKN-- 765

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1883 NLAKQDLMHTTkcqsalLSEQAQLQKDVSQWTARLESCQKETETKEQQLQELQDEIRESKLQLDQQEMvfQKLQKERESE 1962
Cdd:TIGR00606  766 DIEEQETLLGT------IMPEEESAKVCLTDVTIMERFQMELKDVERKIAQQAAKLQGSDLDRTVQQV--NQEKQEKQHE 837

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1963 EQKLVASIVSLEQQQGQLERELMDQKSKLEWLLTDVSAAEGRLRTLQKEERCTESLEKMLSQAKQQLSEREQQLMEKSGD 2042
Cdd:TIGR00606  838 LDTVVSKIELNRKLIQDQQEQIQHLKSKTNELKSEKLQIGTNLQRRQQFEEQLVELSTEVQSLIREIKDAKEQDSPLETF 917

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 2043 LLALQKEADGmradfslLRNQFLTERKKAEKQVAGLKEALK---IQRSQLEKNLLEQKqENSCMQKEMATIELVAQ--DN 2117
Cdd:TIGR00606  918 LEKDQQEKEE-------LISSKETSNKKAQDKVNDIKEKVKnihGYMKDIENKIQDGK-DDYLKQKETELNTVNAQleEC 989

                          810       820
                   ....*....|....*....|....
gi 1958764989 2118 HERARRLMKELRQMQQEYLELKKQ 2141
Cdd:TIGR00606  990 EKHQEKINEDMRLMRQDIDTQKIQ 1013
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1862-2141 1.88e-08

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 60.07  E-value: 1.88e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1862 QDKREAlnslQKELENTQDhlNLAK-QDLMHTTKCQSALLSEQAQL------------QKDVSQWTARLESCQKETETKE 1928
Cdd:TIGR02168  172 ERRKET----ERKLERTRE--NLDRlEDILNELERQLKSLERQAEKaerykelkaelrELELALLVLRLEELREELEELQ 245

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1929 QQLQELQDEIRESKLQLDQQEMVFQKLQK---ERESEEQKLVASIVSLEQQQGQLERELMDQKSKLEWLLTDVSAAEGRL 2005
Cdd:TIGR02168  246 EELKEAEEELEELTAELQELEEKLEELRLevsELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQL 325

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 2006 RTLQKEERC-----------TESLEKMLSQAKQQLSEREQQLMEKSGDLLALQKEADGMRADFSLLRNQFLTERKK---A 2071
Cdd:TIGR02168  326 EELESKLDElaeelaeleekLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEierL 405

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1958764989 2072 EKQVAGLKEALKIQRSQLEKNLLE------QKQENSCMQKEMATIELVAQDN--HERARRLMKELRQMQQEYLELKKQ 2141
Cdd:TIGR02168  406 EARLERLEDRRERLQQEIEELLKKleeaelKELQAELEELEEELEELQEELErlEEALEELREELEEAEQALDAAERE 483
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
438-1052 1.91e-08

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 59.69  E-value: 1.91e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  438 QLEDTGKQIVAAQTRLSELHHEIEAAEQKVLRATQEFKQLEEaiRQKKISEAEKDLLlkqlsgrlrhlnKLRQEALDLEA 517
Cdd:PRK03918   194 LIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEE--LKEEIEELEKELE------------SLEGSKRKLEE 259

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  518 QLEKQRKEIAEKHEEINSaqlatdlLDSKDPKQSHMKaqkrGKEQQLDIMNKQYTQLESRLDEILCRIATETEEIKDLEQ 597
Cdd:PRK03918   260 KIRELEERIEELKKEIEE-------LEEKVKELKELK----EKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEE 328

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  598 QLTDGQiaANEALKKDLEGVISGLQEYLGTIKGQaAQAQNECRKLQDEKETLLQRLTEVKQEKDELEIvamdaENMRKEL 677
Cdd:PRK03918   329 RIKELE--EKEERLEELKKKLKELEKRLEELEER-HELYEEAKAKKEELERLKKRLTGLTPEKLEKEL-----EELEKAK 400

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  678 AELENALQEQHEVNASLQQAQGDLSAYETELETQLKLKDAETSQLKQE-LENLVRRTQLEQSVLQTELEKERQSLRDALG 756
Cdd:PRK03918   401 EEIEEEISKITARIGELKKEIKELKKAIEELKKAKGKCPVCGRELTEEhRKELLEEYTAELKRIEKELKEIEEKERKLRK 480

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  757 KAQSSEEKQQENSELRAQLKqlqddnslLKKQLKDFQSHLNHvvdglIHPEEVAARVDELRK-RLKLGAGEMRIHSPSDV 835
Cdd:PRK03918   481 ELRELEKVLKKESELIKLKE--------LAEQLKELEEKLKK-----YNLEELEKKAEEYEKlKEKLIKLKGEIKSLKKE 547

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  836 LgKSLADLQKQFSEILARSQWEKEEAQVRERKLHEEMALQQEKLANGQEEFKQACERALEArikfdkRQHNARIQQLENE 915
Cdd:PRK03918   548 L-EKLEELKKKLAELEKKLDELEEELAELLKELEELGFESVEELEERLKELEPFYNEYLEL------KDAEKELEREEKE 620

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  916 IHYLQENLKSMEKiqgltdlQLQEADEEKERILAQLQELEKKKRRED-ARSQEQFLGLDTELKSLKKAVaasdklaaael 994
Cdd:PRK03918   621 LKKLEEELDKAFE-------ELAETEKRLEELRKELEELEKKYSEEEyEELREEYLELSRELAGLRAEL----------- 682

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1958764989  995 tiakEQLKSLHGTVMRINQERAEELQEAERSSREamqaAKDLSRAEAEIELLQHLLRE 1052
Cdd:PRK03918   683 ----EELEKRREEIKKTLEKLKEELEEREKAKKE----LEKLEKALERVEELREKVKK 732
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1759-1984 2.05e-08

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 58.62  E-value: 2.05e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1759 QRQLLERDRRETERVRAETQALQSCIECLNKEKEHLQEQCESWEKKSSHAKRVLAATEESNNTEQSKLGQLEVSVRKLQQ 1838
Cdd:COG4942     18 QADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRA 97

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1839 ELELLsQDKLALHSDSAQeqqqlqdkREALNSLQKELENTQDHLNLAKQDLMHttkcqSALLSEQAQLQKDVSQWTARLE 1918
Cdd:COG4942     98 ELEAQ-KEELAELLRALY--------RLGRQPPLALLLSPEDFLDAVRRLQYL-----KYLAPARREQAEELRADLAELA 163

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1958764989 1919 SCQKETETKEQQLQELQDEIRESKLQLDQQEMVFQKLQKERESEEQKLVASIVSLEQQQGQLEREL 1984
Cdd:COG4942    164 ALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALI 229
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1410-2050 3.02e-08

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 59.31  E-value: 3.02e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1410 EKSLKHHEDIVDEIECLEKTLLKRRSELREADRLLAEAESELACTKEKTKSAVEKftdakrnLLQTESDAEALEKRAQEt 1489
Cdd:PRK03918   161 ENAYKNLGEVIKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSE-------LPELREELEKLEKEVKE- 232

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1490 alnLVKAEQQLRLLQADAEDLEQHKIKQEEILKEINKVvaakdadfqcLNEKKEKLtEELQSLQRDIKAAEVNEDHHLQV 1569
Cdd:PRK03918   233 ---LEELKEEIEELEKELESLEGSKRKLEEKIRELEER----------IEELKKEI-EELEEKVKELKELKEKAEEYIKL 298

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1570 LKESESLLQAKRaELETLKSQVTSQQQELAVLDSQLGHRREELlllqdsltqakadlqEALTLGETEVAEKCSHIREVKS 1649
Cdd:PRK03918   299 SEFYEEYLDELR-EIEKRLSRLEEEINGIEERIKELEEKEERL---------------EELKKKLKELEKRLEELEERHE 362

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1650 LLEELSFQKGELNvHISERRTQLTLIKQEIEkeeenlevvLQQLSKHKTElknvadiLQLETNELQslklqhdQKVVELE 1729
Cdd:PRK03918   363 LYEEAKAKKEELE-RLKKRLTGLTPEKLEKE---------LEELEKAKEE-------IEEEISKIT-------ARIGELK 418

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1730 KTQVDLLEGKLELESLQQTAQQQRREL--ERQRQLLERDRRETERVRAETQALQSCIECLNKEKEHLQ------------ 1795
Cdd:PRK03918   419 KEIKELKKAIEELKKAKGKCPVCGRELteEHRKELLEEYTAELKRIEKELKEIEEKERKLRKELRELEkvlkkeselikl 498

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1796 ----EQCESWEKK-SSHAKRVLAATEESNNTEQSKLGQLEVSVRKLQQELELLSqdklALHSDSAQEQQQLQDKREALNS 1870
Cdd:PRK03918   499 kelaEQLKELEEKlKKYNLEELEKKAEEYEKLKEKLIKLKGEIKSLKKELEKLE----ELKKKLAELEKKLDELEEELAE 574

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1871 LQKELEN----TQDHLNLAKQDLMHTTKCQSALLSEQAQLQKDVSqwtaRLESCQKETETKEQQLQELQDEIRESKLQLD 1946
Cdd:PRK03918   575 LLKELEElgfeSVEELEERLKELEPFYNEYLELKDAEKELEREEK----ELKKLEEELDKAFEELAETEKRLEELRKELE 650

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1947 QQEMVFQKLQKERESEEqklvasIVSLEQQQGQLERELMDQKSKLEWLLTDVSAAEGRLRTLQKEERCTESLEKMLsqak 2026
Cdd:PRK03918   651 ELEKKYSEEEYEELREE------YLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEEREKAKKELEKLEKAL---- 720

                          650       660
                   ....*....|....*....|....
gi 1958764989 2027 qqlsEREQQLMEKSGDLLALQKEA 2050
Cdd:PRK03918   721 ----ERVEELREKVKKYKALLKER 740
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 270-1094 3.87e-08

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 58.83  E-value: 3.87e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  270 EEIERLEKDLEKKTVETEELKNKQTKFLEEIKHQDKLNKSLKEEAMLQKQSCEELESDLNTKKELLKQKTVELTRACQKQ 349
Cdd:pfam02463  166 RLKRKKKEALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQEL 245

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  350 YELEQElafyKIDAKFEPLNYYPSEYAEMDKSpdespyigksrykrnmfatetyIVSDAQAVQVRKMVPDGGQLRHEHAP 429
Cdd:pfam02463  246 LRDEQE----EIESSKQEIEKEEEKLAQVLKE----------------------NKEEEKEKKLQEEELKLLAKEEEELK 299

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  430 RAQAPPDVQLEDTGKQIVAAQTRLSELHHEIEAAEQKVLRATQEFKQLEEAIRQKKISEAEK-DLLLKQLSGRLRHLNKL 508
Cdd:pfam02463  300 SELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELeKLQEKLEQLEEELLAKK 379

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  509 RQEALDLEAQLEKQRKEIAEKHEEINSAQLATDLLDSKDpkqshMKAQKRGKEQQLDIMNKQYTQLESRLDEILCRIATE 588
Cdd:pfam02463  380 KLESERLSSAAKLKEEELELKSEEEKEAQLLLELARQLE-----DLLKEEKKEELEILEEEEESIELKQGKLTEEKEELE 454

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  589 TEEIKDLEQQLTDGQIAANEALKKDLEGVISGLQEYLGTIKGQAAQAQNECRK-------LQDEKETLLQRLTEVKQEKD 661
Cdd:pfam02463  455 KQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSglkvllaLIKDGVGGRIISAHGRLGDL 534

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  662 ELEIVAMDAENMRKELAELENALQEQHEVNASLQQAQGDLSAYETELETQLKLKDAETSQLKQELENLVRRTQLEQSVLQ 741
Cdd:pfam02463  535 GVAVENYKVAISTAVIVEVSATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLE 614

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  742 TELE-------------KERQSLRDALGKAQSSEEKQQENSELRAQLKQLQDDNSLLKKQLKDFQSHLNHVVDGLIHPEE 808
Cdd:pfam02463  615 ADEDdkrakvvegilkdTELTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEI 694

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  809 VAARVDELRKRLKLGA------------GEMRIHSPSDVLGKSLADLQKQFSEI---LARSQWEKEEAQVRERKLHEEMA 873
Cdd:pfam02463  695 LRRQLEIKKKEQREKEelkklkleaeelLADRVQEAQDKINEELKLLKQKIDEEeeeEEKSRLKKEEKEEEKSELSLKEK 774

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  874 LQQEKLANGQEEFKQACERALEARIKFDKR----------QHNARIQQLENEIHYLQENLKSMEKIQGLTDLQLQEADEE 943
Cdd:pfam02463  775 ELAEEREKTEKLKVEEEKEEKLKAQEEELRaleeelkeeaELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEE 854

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  944 KERILAQLQELEKKKRREDARSQEQFLGLDTELKSLKKAVAASDKLAAAELTIAKEQLKSLHGTVMRINQERAEELQEAE 1023
Cdd:pfam02463  855 ELERLEEEITKEELLQELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYE 934

                          810       820       830       840       850       860       870
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1958764989 1024 RSSREAMQAAKDLSRAEAEIELLQHLLREREGQFRDEMENAHVGSKgANLQLLEIEALKEAMAKQRAEITR 1094
Cdd:pfam02463  935 EEPEELLLEEADEKEKEENNKEEEEERNKRLLLAKEELGKVNLMAI-EEFEEKEERYNKDELEKERLEEEK 1004
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
449-1021 4.61e-08

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 58.51  E-value: 4.61e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  449 AQTRLSELHHEIEAAEQKVLRAT-----QEFKQLEEAIRQKKISEAEKDLLLKQLSGRLRHLNKLRQEALDLEAQLEKQR 523
Cdd:PRK02224   185 QRGSLDQLKAQIEEKEEKDLHERlngleSELAELDEEIERYEEQREQARETRDEADEVLEEHEERREELETLEAEIEDLR 264

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  524 KEIAEKHEEinsaqlatdlldskdpkQSHMKAQKRGKEQQLDimnkqytQLESRLDEILCRIATETEEIKDLEQQltdgq 603
Cdd:PRK02224   265 ETIAETERE-----------------REELAEEVRDLRERLE-------ELEEERDDLLAEAGLDDADAEAVEAR----- 315

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  604 iaanealKKDLEGVISGLQEYLGTIKGQAAQAQNECRKLQDEKETLLQRLTEVKQEKDELEivaMDAENMRKELAELENA 683
Cdd:PRK02224   316 -------REELEDRDEELRDRLEECRVAAQAHNEEAESLREDADDLEERAEELREEAAELE---SELEEAREAVEDRREE 385

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  684 LQEQHEVNASLQQAQGDLSAYETELETQLKLKDAETSQLKQELenlvrrtqleqsvlqTELEKERQSLRDALGKAQ---- 759
Cdd:PRK02224   386 IEELEEEIEELRERFGDAPVDLGNAEDFLEELREERDELRERE---------------AELEATLRTARERVEEAEalle 450

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  760 ------------------SSEEKQQENSELRAQLKQLQDDNSLLKKQLkdfqshlnhvvDGLIHPEEVAARVDELRKRLK 821
Cdd:PRK02224   451 agkcpecgqpvegsphveTIEEDRERVEELEAELEDLEEEVEEVEERL-----------ERAEDLVEAEDRIERLEERRE 519

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  822 LGAGEMRIHSPS-DVLGKSLADLQKQFSEILARSQWEKEEAQvrerKLHEEMALQQEKLANGQEEfKQACERALEARIKF 900
Cdd:PRK02224   520 DLEELIAERRETiEEKRERAEELRERAAELEAEAEEKREAAA----EAEEEAEEAREEVAELNSK-LAELKERIESLERI 594

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  901 DKRQhnARIQQLENEIHYLQENLKSMEKIQGLTDLQLQEADEEKERILAQLQELEKKKRREDARSQEQFLG--------L 972
Cdd:PRK02224   595 RTLL--AAIADAEDEIERLREKREALAELNDERRERLAEKRERKRELEAEFDEARIEEAREDKERAEEYLEqveekldeL 672

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1958764989  973 DTELKSLKKAVAASDKlAAAELTIAKEQLKSLHGTVMRINQ--ERAEELQE 1021
Cdd:PRK02224   673 REERDDLQAEIGAVEN-ELEELEELRERREALENRVEALEAlyDEAEELES 722
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
641-1054 4.89e-08

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 58.54  E-value: 4.89e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  641 KLQDEKETLLQRLTEVKQEKDELEIVAMDAENMRKEL----AELENALQEQHEVNASLQQAQGDLSAYETELETQLKLKD 716
Cdd:PRK03918   159 DYENAYKNLGEVIKEIKRRIERLEKFIKRTENIEELIkekeKELEEVLREINEISSELPELREELEKLEKEVKELEELKE 238

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  717 AETSQLKQELENLVRRTQLEQSVLQT-----ELEKERQSLRDALGKAQSSEEKQQENSELRAQLKQLQDDNSLLKKQLKD 791
Cdd:PRK03918   239 EIEELEKELESLEGSKRKLEEKIRELeerieELKKEIEELEEKVKELKELKEKAEEYIKLSEFYEEYLDELREIEKRLSR 318

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  792 FQSHLNHVVDGLIHPEEVAARVDELRKRLKlgagemrihspsdVLGKSLADLqKQFSEILARSQWEKEEAQVRERKLHEe 871
Cdd:PRK03918   319 LEEEINGIEERIKELEEKEERLEELKKKLK-------------ELEKRLEEL-EERHELYEEAKAKKEELERLKKRLTG- 383

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  872 maLQQEKLANGQEEFKQACERALEARIKFdkrqhNARIQQLENEIHYLQENLKSMEKIQGLTDLQLQEADEE-KERILAQ 950
Cdd:PRK03918   384 --LTPEKLEKELEELEKAKEEIEEEISKI-----TARIGELKKEIKELKKAIEELKKAKGKCPVCGRELTEEhRKELLEE 456

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  951 LQELEKKKRREDARSQEQFLGLDTELKSLKKAVAASDKLAAAELTIakEQLKSLHGTVMRINQERAEE-LQEAERSSREA 1029
Cdd:PRK03918   457 YTAELKRIEKELKEIEEKERKLRKELRELEKVLKKESELIKLKELA--EQLKELEEKLKKYNLEELEKkAEEYEKLKEKL 534

                          410       420
                   ....*....|....*....|....*
gi 1958764989 1030 MQAAKDLSRAEAEIELLQHLLRERE 1054
Cdd:PRK03918   535 IKLKGEIKSLKKELEKLEELKKKLA 559
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1408-1770 5.37e-08

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 58.54  E-value: 5.37e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1408 EIEKSLKHHEDIVDEIECLEKTLLKRRSELREADRLLAEAESELACTKEKTKSAVEKFTDAKRNLLQTESDAEALEKRAQ 1487
Cdd:TIGR02169  682 RLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELK 761

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1488 ETALNLVKAEQQLRLLQADAEDLEQH------------KIKQEEILKEINKVVAAKDADFQCLNEKKEKLTEELQSLQRD 1555
Cdd:TIGR02169  762 ELEARIEELEEDLHKLEEALNDLEARlshsripeiqaeLSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQ 841

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1556 IKAAEVNEdhhlqvlKESESLLQAKRAELETLKSQVTSQQQELAVLDSQLGHRREELLLLQDSLTQAKADLQEAltlgET 1635
Cdd:TIGR02169  842 RIDLKEQI-------KSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEEL----EA 910

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1636 EVAEKCSHIREVKSLLEELSFQKGELNVHISErrtqltlikqeiekeeenlevvLQQLSKHKTELKNVADILQLETNELQ 1715
Cdd:TIGR02169  911 QIEKKRKRLSELKAKLEALEEELSEIEDPKGE----------------------DEEIPEEELSLEDVQAELQRVEEEIR 968

                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1958764989 1716 SLKLQHDQKVVELEKTQVDLLEgkleLESLQQTAQQQRRELERQRQLLERDRRET 1770
Cdd:TIGR02169  969 ALEPVNMLAIQEYEEVLKRLDE----LKEKRAKLEEERKAILERIEEYEKKKREV 1019
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
481-960 6.65e-08

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 57.86  E-value: 6.65e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  481 IRQKKISEAEKDLllKQLSGRLRHLNKLRQEALDLEAQLEKQRKEIAEKHEEINSAQLATDLLDskdpkqshMKAQKRGK 560
Cdd:COG4717     68 LNLKELKELEEEL--KEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLP--------LYQELEAL 137

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  561 EQQLDIMNKQYTQLESRLDEILCRIatetEEIKDLEQQLTDGQIAANEALKKDLEGVISGLQeylgtikgqaaQAQNECR 640
Cdd:COG4717    138 EAELAELPERLEELEERLEELRELE----EELEELEAELAELQEELEELLEQLSLATEEELQ-----------DLAEELE 202

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  641 KLQDEKETLLQRLTEVKQEKDELEivamdaenmrKELAELENALQEQHEVNaSLQQAQGDLSAyETELETQLKLKDAETS 720
Cdd:COG4717    203 ELQQRLAELEEELEEAQEELEELE----------EELEQLENELEAAALEE-RLKEARLLLLI-AAALLALLGLGGSLLS 270

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  721 QLKQELENLVRRTQLeQSVLQTELEKERQSLRDALGKAQSSEEKQQ-ENSELRAQLKQLQDDNSLLKKQLKDFQSHLNHV 799
Cdd:COG4717    271 LILTIAGVLFLVLGL-LALLFLLLAREKASLGKEAEELQALPALEElEEEELEELLAALGLPPDLSPEELLELLDRIEEL 349

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  800 VdglihpeEVAARVDELRKRLKlgagemrihspsdvlgksLADLQKQFSEILARSQWEKEEAQVRERKLHEEMALQQEKL 879
Cdd:COG4717    350 Q-------ELLREAEELEEELQ------------------LEELEQEIAALLAEAGVEDEEELRAALEQAEEYQELKEEL 404

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  880 ANGQEEFKQACERALEARIKFDKRQHNARIQQLENEIHYLQENLKSM-EKIQGL--------TDLQLQEADEEKERILAQ 950
Cdd:COG4717    405 EELEEQLEELLGELEELLEALDEEELEEELEELEEELEELEEELEELrEELAELeaeleqleEDGELAELLQELEELKAE 484

                          490
                   ....*....|
gi 1958764989  951 LQELEKKKRR 960
Cdd:COG4717    485 LRELAEEWAA 494
mukB PRK04863
chromosome partition protein MukB;
444-820 7.62e-08

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 58.04  E-value: 7.62e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  444 KQIVAAQTRLSELHHEIEAAEQKVLRATQEFKQL--------EEAIRQKKISEAEKDLLlkQLSGRLRHLNKLRQEALDL 515
Cdd:PRK04863   300 RQLAAEQYRLVEMARELAELNEAESDLEQDYQAAsdhlnlvqTALRQQEKIERYQADLE--ELEERLEEQNEVVEEADEQ 377

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  516 EAQLEkQRKEIAEkhEEINS--AQLAtdlldskDPKQSHMKAQKRgkeqqldimNKQYTQLESRLDEI--LCRIATETEE 591
Cdd:PRK04863   378 QEENE-ARAEAAE--EEVDElkSQLA-------DYQQALDVQQTR---------AIQYQQAVQALERAkqLCGLPDLTAD 438

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  592 -IKDLEQQLTDGQIAANEALKkDLEGVISGLQEylgtIKGQAAQAQNECRKLQDE--KETLLQRLTEVKQEKDELEIVAM 668
Cdd:PRK04863   439 nAEDWLEEFQAKEQEATEELL-SLEQKLSVAQA----AHSQFEQAYQLVRKIAGEvsRSEAWDVARELLRRLREQRHLAE 513

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  669 DAENMRKELAELENALQEQHEVNASLQQAQGDLSA---YETELETQLKLKDAETSQLKQELENLV-RRTQLEQSvlQTEL 744
Cdd:PRK04863   514 QLQQLRMRLSELEQRLRQQQRAERLLAEFCKRLGKnldDEDELEQLQEELEARLESLSESVSEAReRRMALRQQ--LEQL 591

                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1958764989  745 EKERQSLRdalGKAQSSEEKQQENSELRAQLKQLQDDNSLLKKQLkdfQSHLNHVVDGLIHPEEVAARVDELRKRL 820
Cdd:PRK04863   592 QARIQRLA---ARAPAWLAAQDALARLREQSGEEFEDSQDVTEYM---QQLLERERELTVERDELAARKQALDEEI 661
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 460-1060 8.18e-08

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 57.67  E-value: 8.18e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  460 IEAAEQKVLRATQEFKQLEEAIRQKKISEAEKDLLLKQLSGRLRHLNKLRQEaldlEAQLEKQRKEIaekheeinsaqla 539
Cdd:TIGR00618  224 LEKELKHLREALQQTQQSHAYLTQKREAQEEQLKKQQLLKQLRARIEELRAQ----EAVLEETQERI------------- 286

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  540 tDLLDSKDPKQSHMKAQKRGKEQQLDIMNKQYTQLESRLDEILCRIATETEEIKDLEQQLTDGQIAANEALKKDLEGVIS 619
Cdd:TIGR00618  287 -NRARKAAPLAAHIKAVTQIEQQAQRIHTELQSKMRSRAKLLMKRAAHVKQQSSIEEQRRLLQTLHSQEIHIRDAHEVAT 365

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  620 GLQEylgtIKGQAAQAQNECRKLQDEKETLLQRLTEVKQEKDELEIVAMDAENMRKELAELENALQEQHEVNASLQQAQG 699
Cdd:TIGR00618  366 SIRE----ISCQQHTLTQHIHTLQQQKTTLTQKLQSLCKELDILQREQATIDTRTSAFRDLQGQLAHAKKQQELQQRYAE 441

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  700 DLSAYETELETQLKLKDAETSQLKQELENLVRRTQLEQSVLQTELEKERQSLRDALGKAQSSEEKQQENSELRAQLKQLQ 779
Cdd:TIGR00618  442 LCAAAITCTAQCEKLEKIHLQESAQSLKEREQQLQTKEQIHLQETRKKAVVLARLLELQEEPCPLCGSCIHPNPARQDID 521

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  780 DDNSLLKKQLKDFQSHLNHVVDGlihpEEVAARVDELRKRLKLGAGEM---------------RIHSPSDVLGKSLADLQ 844
Cdd:TIGR00618  522 NPGPLTRRMQRGEQTYAQLETSE----EDVYHQLTSERKQRASLKEQMqeiqqsfsiltqcdnRSKEDIPNLQNITVRLQ 597

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  845 KQFSEILARSQWEKEEAQVRERKLHEEMALQQEKLANGQEEFKQACERALEAR-----IKFDKRQHNARIQQLENEihYL 919
Cdd:TIGR00618  598 DLTEKLSEAEDMLACEQHALLRKLQPEQDLQDVRLHLQQCSQELALKLTALHAlqltlTQERVREHALSIRVLPKE--LL 675

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  920 QENLKSMEKIQGLTDlQLQEADEEKERILAQLQELEKKKRREDARSQEQFLGldteLKSLKKAVAASDKLAAAELTIAKE 999
Cdd:TIGR00618  676 ASRQLALQKMQSEKE-QLTYWKEMLAQCQTLLRELETHIEEYDREFNEIENA----SSSLGSDLAAREDALNQSLKELMH 750

                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1958764989 1000 QLKSLHGTVMRINQERAEELQEAERSSREAMQAAKDLSRAEAEIELLQHLLREREGQFRDE 1060
Cdd:TIGR00618  751 QARTVLKARTEAHFNNNEEVTAALQTGAELSHLAAEIQFFNRLREEDTHLLKTLEAEIGQE 811
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 445-729 9.61e-08

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 57.77  E-value: 9.61e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  445 QIVAAQTRLSELHHEIEAAEQKVLRATQEFKQLEEAIR--QKKISEAEKDLLLKQLSGRLRHLNKLRQEALDLEAQLEKQ 522
Cdd:TIGR02169  738 RLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHklEEALNDLEARLSHSRIPEIQAELSKLEEEVSRIEARLREI 817

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  523 RKEIAEKHEEinsAQLATDLLDSKDPKQSHMKAQKRGKEQQLDIMNKQYTQLESRLDEILCRIATETEEIKDLEQQltdg 602
Cdd:TIGR02169  818 EQKLNRLTLE---KEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKE---- 890

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  603 qiaanealKKDLEGVISGLQEYLGTIKGQAAQAQNECRKLQDEKETLLQRLTEVKQEKDELEIVA---MDAENMRKELAE 679
Cdd:TIGR02169  891 --------RDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPeeeLSLEDVQAELQR 962

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|
gi 1958764989  680 LENALQEQHEVNASLQQAQGDLSAYETELETQLKLKDAETSQLKQELENL 729
Cdd:TIGR02169  963 VEEEIRALEPVNMLAIQEYEEVLKRLDELKEKRAKLEEERKAILERIEEY 1012
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 1715-2076 1.05e-07

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 57.44  E-value: 1.05e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1715 QSLKLQHDQKVVElEKTQVDLLEgKLELESLQQTAQQQRRELERQRQLlerdrRETERVRAETQALQSCI----ECLNKE 1790
Cdd:pfam17380  273 QLLHIVQHQKAVS-ERQQQEKFE-KMEQERLRQEKEEKAREVERRRKL-----EEAEKARQAEMDRQAAIyaeqERMAME 345

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1791 KEHLQEQCESWEKKsshakrvlaateesnnteqsklgqlevsvrklqQELELLSQDKLALHSDSAQEQQQLQDKREALNS 1870
Cdd:pfam17380  346 RERELERIRQEERK---------------------------------RELERIRQEEIAMEISRMRELERLQMERQQKNE 392

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1871 -LQKELENTQDHlNLAKQDLMHTTKCQSALLSEQAQLQKDVSQWTARLESCQKETETKEQQLQELQDEIRESKLQLDQQE 1949
Cdd:pfam17380  393 rVRQELEAARKV-KILEEERQRKIQQQKVEMEQIRAEQEEARQREVRRLEEERAREMERVRLEEQERQQQVERLRQQEEE 471

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1950 MVFQKLQKERESEEQKLVASI--VSLEQQQGQLERELMDQKSKLEWLLTDVsaaEGRLRTLQKEERCTESLEKMLSQAKQ 2027
Cdd:pfam17380  472 RKRKKLELEKEKRDRKRAEEQrrKILEKELEERKQAMIEEERKRKLLEKEM---EERQKAIYEEERRREAEEERRKQQEM 548

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|....*....
gi 1958764989 2028 QLSEREQQLMEKSGDllaLQKEADGMRADFSLLRNQFLTERKKAEKQVA 2076
Cdd:pfam17380  549 EERRRIQEQMRKATE---ERSRLEAMEREREMMRQIVESEKARAEYEAT 594
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 1320-1992 1.12e-07

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 57.29  E-value: 1.12e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1320 HRDLENEVSRLEDITHHLKSKHQEERWLkTSRQHPEKEVEELHRNIDDLVQEKKELELEVEELHRTVERHQQRRDFidgn 1399
Cdd:TIGR00618  218 HERKQVLEKELKHLREALQQTQQSHAYL-TQKREAQEEQLKKQQLLKQLRARIEELRAQEAVLEETQERINRARKA---- 292

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1400 venlmteLEIEKSLKHHEDIVDEIECLEKTLLKRRSELREADRLLAEAESELACTKEKTKSAVEKFTDAKRNLLQTESDA 1479
Cdd:TIGR00618  293 -------APLAAHIKAVTQIEQQAQRIHTELQSKMRSRAKLLMKRAAHVKQQSSIEEQRRLLQTLHSQEIHIRDAHEVAT 365

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1480 EALEKRAQETALnlvkaEQQLRLLQAD---AEDLEQHKIKQEEILKEINKVVAAKDADFQCLNEKKEKLTEELQSLQRDI 1556
Cdd:TIGR00618  366 SIREISCQQHTL-----TQHIHTLQQQkttLTQKLQSLCKELDILQREQATIDTRTSAFRDLQGQLAHAKKQQELQQRYA 440

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1557 KAAEVNEDHHLQVLKESESLLQAKRAELETLKSQVTSQQQEL-------AVLDSQLGHRREELLLLQDSLTQAKADLQEA 1629
Cdd:TIGR00618  441 ELCAAAITCTAQCEKLEKIHLQESAQSLKEREQQLQTKEQIHlqetrkkAVVLARLLELQEEPCPLCGSCIHPNPARQDI 520

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1630 LTLGETEvAEKCSHIREVKSLLEELSFQKGELnvhiSERRTQLTLIKQEIEKEEENLEVVLQQLSKHKTELKNVADILQL 1709
Cdd:TIGR00618  521 DNPGPLT-RRMQRGEQTYAQLETSEEDVYHQL----TSERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITVR 595

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1710 ETNELQSLkLQHDQKVVELEKTQVDLLEGKLELESLQQTAQQQRRELERQRQLLERDRRETERVRAETQALQScieclNK 1789
Cdd:TIGR00618  596 LQDLTEKL-SEAEDMLACEQHALLRKLQPEQDLQDVRLHLQQCSQELALKLTALHALQLTLTQERVREHALSI-----RV 669

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1790 EKEHLQEQCESWEKKSSHAKRVLAATEESNNTEQSKLGQLEVSVRKLQQELELLSQDKLALhsdsaqeQQQLQDKREALN 1869
Cdd:TIGR00618  670 LPKELLASRQLALQKMQSEKEQLTYWKEMLAQCQTLLRELETHIEEYDREFNEIENASSSL-------GSDLAAREDALN 742

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1870 SLQKELENTQDHlNLAKQDLMHTTKCQSALLSEqaQLQKDVSQWTARLESCQKETETKEQQLQELQDEIRES-KLQLDQQ 1948
Cdd:TIGR00618  743 QSLKELMHQART-VLKARTEAHFNNNEEVTAAL--QTGAELSHLAAEIQFFNRLREEDTHLLKTLEAEIGQEiPSDEDIL 819

                          650       660       670       680
                   ....*....|....*....|....*....|....*....|....*..
gi 1958764989 1949 EMVFQKLQKERESEEQKLV---ASIVSLEQQQGQLERELMDQKSKLE 1992
Cdd:TIGR00618  820 NLQCETLVQEEEQFLSRLEeksATLGEITHQLLKYEECSKQLAQLTQ 866
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1842-2073 1.49e-07

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 55.93  E-value: 1.49e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1842 LLSQDKLALHSDSAQEQQQLQDKREALNSLQKELENTQDHLNLAKQDLMHTTKCQSALLSEQAQLQKDVSQWTARLESCQ 1921
Cdd:COG4942     10 LLALAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELE 89

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1922 KETETKEQQLQELQDEIR---------------------ESKLQLDQQEMVFQKLQKERESEEQKLVASIVSLEQQQGQL 1980
Cdd:COG4942     90 KEIAELRAELEAQKEELAellralyrlgrqpplalllspEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAEL 169

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1981 ERelmdQKSKLEWLLTDVSAAEGRLRTLQKEErcteslEKMLSQAKQQLSEREQQLMEKSGDLLALQKEADGMRADFSLL 2060
Cdd:COG4942    170 EA----ERAELEALLAELEEERAALEALKAER------QKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAA 239

                          250
                   ....*....|...
gi 1958764989 2061 RNQFLTERKKAEK 2073
Cdd:COG4942    240 AERTPAAGFAALK 252
LRR_8 pfam13855
Leucine rich repeat;
170-227 1.57e-07

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 49.83  E-value: 1.57e-07
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1958764989  170 NLQKLNLAGNEIEHI-PGWFsKKLKSLRVLNLKGNKISSLQDVSklkpLQDLTSLTLID 227
Cdd:pfam13855    2 NLRSLDLSNNRLTSLdDGAF-KGLSNLKVLDLSNNLLTTLSPGA----FSGLPSLRYLD 55
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 1743-1990 1.93e-07

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 56.88  E-value: 1.93e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1743 ESLQQTAQQQRRELERQrqlLERDRRETERVRAETQALQSCIECLNK--------EKEHLQEQCESWEKKSSHAKRVLAA 1814
Cdd:COG3096    835 EAELAALRQRRSELERE---LAQHRAQEQQLRQQLDQLKEQLQLLNKllpqanllADETLADRLEELREELDAAQEAQAF 911

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1815 TEESNNTeqskLGQLEVSVRKLQQELEllSQDKLALHSDSAQEQQQLQDKR-EALNSL------------QKELENTQDH 1881
Cdd:COG3096    912 IQQHGKA----LAQLEPLVAVLQSDPE--QFEQLQADYLQAKEQQRRLKQQiFALSEVvqrrphfsyedaVGLLGENSDL 985

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1882 LNLAKQDLMHTTKCQSALLSEQAQLQKDVSQWTARLESCQKETETKEQQLQELQDEIRESKLQLDqQEMVfQKLQKERES 1961
Cdd:COG3096    986 NEKLRARLEQAEEARREAREQLRQAQAQYSQYNQVLASLKSSRDAKQQTLQELEQELEELGVQAD-AEAE-ERARIRRDE 1063

                          250       260       270
                   ....*....|....*....|....*....|..
gi 1958764989 1962 EEQKLVAS---IVSLEQQQGQLERElMDQKSK 1990
Cdd:COG3096   1064 LHEELSQNrsrRSQLEKQLTRCEAE-MDSLQK 1094
PTZ00121 PTZ00121
MAEBL; Provisional
 1431-2130 1.95e-07

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 56.69  E-value: 1.95e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1431 LKRRSELREADRLLAEAESELACTKEKTKSAVEKFTDAKRNLLQTESDAEALEKRAQETA----LNLVKAEQQLRLLQAD 1506
Cdd:PTZ00121  1283 LKKAEEKKKADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKkaaeAAKAEAEAAADEAEAA 1362

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1507 AEDLEQHKIKQEEILKEINKvvAAKDADFQCLNEKKEKLTEELQSLQRDIKAAEVNEDHHLQVLKESESLLQA----KRA 1582
Cdd:PTZ00121  1363 EEKAEAAEKKKEEAKKKADA--AKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKAdeakKKA 1440

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1583 ElETLKSQVTSQQQELAVLDSQLGHRREEllllqdsltQAKADLQEaltlgetEVAEKCSHIREVKSLLEELSFQKGELN 1662
Cdd:PTZ00121  1441 E-EAKKADEAKKKAEEAKKAEEAKKKAEE---------AKKADEAK-------KKAEEAKKADEAKKKAEEAKKKADEAK 1503

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1663 VHISERRTQLTLIKQEIEKEEENLEvvlqqlskhKTELKNVADILQletnelqslKLQHDQKVVELEKTQvdllegKLEL 1742
Cdd:PTZ00121  1504 KAAEAKKKADEAKKAEEAKKADEAK---------KAEEAKKADEAK---------KAEEKKKADELKKAE------ELKK 1559

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1743 ESLQQTAQQQRRELERQRQLLerdRRETERVRAETQALQSCIECLNKEKEHLQEQCESWEKKSSHAKRVLAATEESNNTE 1822
Cdd:PTZ00121  1560 AEEKKKAEEAKKAEEDKNMAL---RKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVE 1636

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1823 QSKLGQLE-----VSVRKLQQELELLSQDKLALHSDSAQEQQQL----QDKREALNSLQKELENTQDHLNLAKQDLMHTT 1893
Cdd:PTZ00121  1637 QLKKKEAEekkkaEELKKAEEENKIKAAEEAKKAEEDKKKAEEAkkaeEDEKKAAEALKKEAEEAKKAEELKKKEAEEKK 1716

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1894 KCQsallseqaQLQKDVSQWTARLESCQKETETKEQQLQELQDEiRESKLQLDQQEMVFQKLQKERESEEQKLVASIVSL 1973
Cdd:PTZ00121  1717 KAE--------ELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKD-EEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDE 1787

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1974 EQQQGQLERELMDQKSKLEWLLTDVSAAEGRLRTLQKEERCTESLEKMLSQAKQQLSEREqQLMEKSGDLLALQKEADGM 2053
Cdd:PTZ00121  1788 EDEKRRMEVDKKIKDIFDNFANIIEGGKEGNLVINDSKEMEDSAIKEVADSKNMQLEEAD-AFEKHKFNKNNENGEDGNK 1866

                          650       660       670       680       690       700       710
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1958764989 2054 RADFSllrnqflTERKKAEKQVAGLKEALKIQrsQLEKNLLEQKQENSCMQKEMATIELVAQDNHERARRLMKELRQ 2130
Cdd:PTZ00121  1867 EADFN-------KEKDLKEDDEEEIEEADEIE--KIDKDDIEREIPNNNMAGKNNDIIDDKLDKDEYIKRDAEETRE 1934
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1429-2039 3.12e-07

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 56.08  E-value: 3.12e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1429 TLLKRRSELREADRLLAEAESELAcTKEKTKSAVEKFTDAKRNLLQTESDAEALEKRAQETALNLVKAE-----QQLRLL 1503
Cdd:COG4913    229 ALVEHFDDLERAHEALEDAREQIE-LLEPIRELAERYAAARERLAELEYLRAALRLWFAQRRLELLEAEleelrAELARL 307

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1504 QADAEDLEQHKIKQEEILKEINKVVAAKDADfqclnekkeklteELQSLQRDIKAAEvnedhhlQVLKESESLLQAKRAE 1583
Cdd:COG4913    308 EAELERLEARLDALREELDELEAQIRGNGGD-------------RLEQLEREIERLE-------RELEERERRRARLEAL 367

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1584 LETLKSQVTSQQQELAVLdsqlghrREELLLLQDSLTQAKADLQEALTLGETEVAEKCSHIREVKSLLEELSFQKGELNV 1663
Cdd:COG4913    368 LAALGLPLPASAEEFAAL-------RAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKSNIPA 440

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1664 HISERRTQLtlikqeiekeeenlevvLQQLSKHKTELKNVADILQLETNE----------LQSLKL------QHDQKVVE 1727
Cdd:COG4913    441 RLLALRDAL-----------------AEALGLDEAELPFVGELIEVRPEEerwrgaiervLGGFALtllvppEHYAAALR 503

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1728 -LEKTQvdlLEGKLELESLQQTAQQQRRELERQRQLLE---------RD------RRETERVRAET-QALQSC-----IE 1785
Cdd:COG4913    504 wVNRLH---LRGRLVYERVRTGLPDPERPRLDPDSLAGkldfkphpfRAwleaelGRRFDYVCVDSpEELRRHpraitRA 580

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1786 CLNKEKEHLqeqcesWEKKSSHAKRVLAATEESNnteQSKLGQLEVSVRKLQQELELLSQDKLALhsdsAQEQQQLQDKR 1865
Cdd:COG4913    581 GQVKGNGTR------HEKDDRRRIRSRYVLGFDN---RAKLAALEAELAELEEELAEAEERLEAL----EAELDALQERR 647

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1866 EALNSLQKELENTQDHlnlakqdlmhttkcqsallseqAQLQKDVSQWTARLESCQKETetkeQQLQELQDEIRESKLQL 1945
Cdd:COG4913    648 EALQRLAEYSWDEIDV----------------------ASAEREIAELEAELERLDASS----DDLAALEEQLEELEAEL 701

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1946 DQQEMVFQKLQKERESEEQKLVASIVSLEQQQGQLERELMDQKSKLEWLLTDVSAAEGRLRtlqKEERCTESLEKMLSQA 2025
Cdd:COG4913    702 EELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLEERFAAALGDA---VERELRENLEERIDAL 778

                          650
                   ....*....|....
gi 1958764989 2026 KQQLSEREQQLMEK 2039
Cdd:COG4913    779 RARLNRAEEELERA 792
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 1517-2091 3.46e-07

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 56.00  E-value: 3.46e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1517 QEEILKEINKVVAAKDADfqcLNEKKEKLTEELQSLQRDIKAAEvnedHHLQVLKESesLLQAKRAELETLKSQvtsqQQ 1596
Cdd:pfam12128  281 RQETSAELNQLLRTLDDQ---WKEKRDELNGELSAADAAVAKDR----SELEALEDQ--HGAFLDADIETAAAD----QE 347

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1597 ELAVLDSQLGHRREELlllqDSLTQAKADLQEALTLGETEVAEKCShiREVKSLLEELSFQKGELNVHISERRTQLtliK 1676
Cdd:pfam12128  348 QLPSWQSELENLEERL----KALTGKHQDVTAKYNRRRSKIKEQNN--RDIAGIKDKLAKIREARDRQLAVAEDDL---Q 418

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1677 QEIEKEEENLEVVLQQLSKHKTELKNVADILQLETNELQS---LKLQHDQKVVELEKTQVDLLEGKLELESLQQTAQQQR 1753
Cdd:pfam12128  419 ALESELREQLEAGKLEFNEEEYRLKSRLGELKLRLNQATAtpeLLLQLENFDERIERAREEQEAANAEVERLQSELRQAR 498

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1754 ReleRQRQLLERDRRETERVRAETQALQSCIECLNKEK----EHLQEQCESWEKkssHAKRVLAA-----------TEES 1818
Cdd:pfam12128  499 K---RRDQASEALRQASRRLEERQSALDELELQLFPQAgtllHFLRKEAPDWEQ---SIGKVISPellhrtdldpeVWDG 572

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1819 NNTEQSKLGQLEVSVRKLQQELELLSQDKLALHSDSAQEQQQLQDKR-----EALNSLQKELENTQDHLNLAKQDLMHTT 1893
Cdd:pfam12128  573 SVGGELNLYGVKLDLKRIDVPEWAASEEELRERLDKAEEALQSAREKqaaaeEQLVQANGELEKASREETFARTALKNAR 652

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1894 KCQSALLSEQAQLQKDVSQWTA-RLESCQKETETKEQQLQELQDEIRESKLQLDQQ--EMVFQKLQKERESEEQ---KLV 1967
Cdd:pfam12128  653 LDLRRLFDEKQSEKDKKNKALAeRKDSANERLNSLEAQLKQLDKKHQAWLEEQKEQkrEARTEKQAYWQVVEGAldaQLA 732

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1968 ASIVSLEQQQGQLERELmdqKSKLEWLLTDVSAAEGRLRTLQKEERCTESLEKMLSQAKQ-------------------- 2027
Cdd:pfam12128  733 LLKAAIAARRSGAKAEL---KALETWYKRDLASLGVDPDVIAKLKREIRTLERKIERIAVrrqevlryfdwyqetwlqrr 809

                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1958764989 2028 -----QLSEREQQLMEKSGDLLALQkeadgmrADFSLLRNQFLTERKKAEKQVAGLKEALKIQRSQLEK 2091
Cdd:pfam12128  810 prlatQLSNIERAISELQQQLARLI-------ADTKLRRAKLEMERKASEKQQVRLSENLRGLRCEMSK 871
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1563-2093 3.85e-07

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 55.69  E-value: 3.85e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1563 EDHHLQVLKESESL-----LQAKRAELETLKSQVTSQQQELAVLDSQlgHRREELLLLQDSLTQAKADLQEAltlgETEV 1637
Cdd:COG4913    238 ERAHEALEDAREQIellepIRELAERYAAARERLAELEYLRAALRLW--FAQRRLELLEAELEELRAELARL----EAEL 311

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1638 AEKCSHIREVKSLLEELsfqKGELNVHISERRTQLTLIkqeiekeeenlevvLQQLSKHKTELKNVADILQletNELQSL 1717
Cdd:COG4913    312 ERLEARLDALREELDEL---EAQIRGNGGDRLEQLERE--------------IERLERELEERERRRARLE---ALLAAL 371

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1718 KLQHDQKVVELEKTQVDLLEGKLELESLQQTAQQQRRELERQRQLLERDRRETERVRAETQALQSCI------------- 1784
Cdd:COG4913    372 GLPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKSNIparllalrdalae 451

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1785 ECLNKEK------EHLQ--EQCESWEK---------------KSSHAKRVLAATEESNnteqsklgqLEVSVRKLQQELE 1841
Cdd:COG4913    452 ALGLDEAelpfvgELIEvrPEEERWRGaiervlggfaltllvPPEHYAAALRWVNRLH---------LRGRLVYERVRTG 522

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1842 LLSQDKLALHSDSAQEQQQLQDKrEALNSLQKELENTQDHLNLAK-QDLMHTTK--CQSALLSEQAQL-QKDVSQWTARL 1917
Cdd:COG4913    523 LPDPERPRLDPDSLAGKLDFKPH-PFRAWLEAELGRRFDYVCVDSpEELRRHPRaiTRAGQVKGNGTRhEKDDRRRIRSR 601

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1918 ----ESCQKETETKEQQLQELQDEIRESKLQLDQQEMVFQKLQKERESEE--QKLVASIVSLEQQQGQLeRELMDQKSKL 1991
Cdd:COG4913    602 yvlgFDNRAKLAALEAELAELEEELAEAEERLEALEAELDALQERREALQrlAEYSWDEIDVASAEREI-AELEAELERL 680

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1992 EWLLTDVSAAEGRLRTLQKEErctESLEKMLSQAKQQLSEREQQLMEKSGDLLALQKEADGMRADFSLLRNQFLTERKKA 2071
Cdd:COG4913    681 DASSDDLAALEEQLEELEAEL---EELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLEERFAA 757

                          570       580
                   ....*....|....*....|....*
gi 1958764989 2072 ---EKQVAGLKEALKIQRSQLEKNL 2093
Cdd:COG4913    758 algDAVERELRENLEERIDALRARL 782
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 1322-2080 4.07e-07

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 55.75  E-value: 4.07e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1322 DLENEVSRLEDITHHLKSKHQEERWLKTSRQHPEKEVEELHRNIDDLVQEKKELELEVEELHRTVERHQQRRDFIDGNVE 1401
Cdd:pfam02463  294 EEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEE 373

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1402 NLMTELEIEKslkhhEDIVDEIECLEKTLLKRRSELREADRLLAEAESELACTKEKTKSAVEKFTDAKRnlLQTESDAEA 1481
Cdd:pfam02463  374 ELLAKKKLES-----ERLSSAAKLKEEELELKSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEE--SIELKQGKL 446

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1482 LEKRAQETALNLVKAEQQLRLLQADAEDLEQHKIKQEEILKEINKVVAAKDADFQclNEKKEKLTEELQSLQRDIKAAEV 1561
Cdd:pfam02463  447 TEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQK--ESKARSGLKVLLALIKDGVGGRI 524

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1562 NEDHHLQVLKEsESLLQAKRAELETLKSQVTSQQQELAVLDSQLGHRREELLLLQDSLTQAKADLQEALTLGETEVAEKC 1641
Cdd:pfam02463  525 ISAHGRLGDLG-VAVENYKVAISTAVIVEVSATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPIL 603

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1642 SHIREVKSLLEELSFQKGELNVHISERRTQLTLIKQEIEKEEENLEVVlQQLSKHKTELKNVADILQLETNELQSLKLQH 1721
Cdd:pfam02463  604 NLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKAKESGLRKG-VSLEEGLAEKSEVKASLSELTKELLEIQELQ 682

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1722 DQKVVELEKTQVDLLEGKLELESLQQTAQQQRRELERQRQLLERDRRETERVRAETQALQSCIECLNKEKEHLQEQCESW 1801
Cdd:pfam02463  683 EKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEK 762

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1802 EKKSSHAKRVLAATEESNNTEQSKLGQLEVSVRKLQQELELLSQDKLALHSDSAQEQQQLqDKREALNSLQKELENTQDH 1881
Cdd:pfam02463  763 EEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALEEELKEEAELLEEEQL-LIEQEEKIKEEELEELALE 841

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1882 LNLAKQDLMHTTKCQSALLSEQAQLQKDVSQWTARLESCQKETETKEQQLQELQDEIRESKLQLDQQEMvfqkLQKERES 1961
Cdd:pfam02463  842 LKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLN----LLEEKEN 917

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1962 EEQKLVASIVSLEQQQGQLERELMDQKSKLEWLLTDVSAAEGRLRTLQKEERcTESLEKMLSQAKQQLSEREQQLMEKSG 2041
Cdd:pfam02463  918 EIEERIKEEAEILLKYEEEPEELLLEEADEKEKEENNKEEEEERNKRLLLAK-EELGKVNLMAIEEFEEKEERYNKDELE 996

                          730       740       750
                   ....*....|....*....|....*....|....*....
gi 1958764989 2042 DLLALQKEADGMRADFSLLRNQFLTERKKAEKQVAGLKE 2080
Cdd:pfam02463  997 KERLEEEKKKLIRAIIEETCQRLKEFLELFVSINKGWNK 1035
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
1921-2134 4.18e-07

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 55.41  E-value: 4.18e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1921 QKETETKEQQLQELQDEIRESKLQLDQQEMVFQKLQKER-----ESEEQKLVASIVSLEQQQGQLERELMDQKSKLEWLL 1995
Cdd:COG3206    167 ELRREEARKALEFLEEQLPELRKELEEAEAALEEFRQKNglvdlSEEAKLLLQQLSELESQLAEARAELAEAEARLAALR 246

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1996 TDVSAAEGRLRTLQKEERcTESLEKMLSQAKQQLSEREQQLMEKSGDLLALQKEADGmradfslLRNQFLTERKKAEKQV 2075
Cdd:COG3206    247 AQLGSGPDALPELLQSPV-IQQLRAQLAELEAELAELSARYTPNHPDVIALRAQIAA-------LRAQLQQEAQRILASL 318

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1958764989 2076 AGLKEALKIQRSQLEKNLLEQKQENSCMQKEMATIeLVAQDNHERARRLMKELRQMQQE 2134
Cdd:COG3206    319 EAELEALQAREASLQAQLAQLEARLAELPELEAEL-RRLEREVEVARELYESLLQRLEE 376
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
270-778 4.37e-07

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 55.31  E-value: 4.37e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  270 EEIERLEKDLEKKTVETEELKNKQTKF---LEEIKHQDKLN----KSLKEEAMLQKQSCEELESDLNTKKELLKQktvEL 342
Cdd:COG4913    338 DRLEQLEREIERLERELEERERRRARLealLAALGLPLPASaeefAALRAEAAALLEALEEELEALEEALAEAEA---AL 414

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  343 TRACQKQYELEQELAFYKidAKfePLNYyPSEYAEM--------DKSPDESPYIGK---------------SRYKRNmFA 399
Cdd:COG4913    415 RDLRRELRELEAEIASLE--RR--KSNI-PARLLALrdalaealGLDEAELPFVGElievrpeeerwrgaiERVLGG-FA 488

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  400 TeTYIVSDAQAVQVRKMV---PDGGQLRHEHAPRAQAPPDV--------------------------------------- 437
Cdd:COG4913    489 L-TLLVPPEHYAAALRWVnrlHLRGRLVYERVRTGLPDPERprldpdslagkldfkphpfrawleaelgrrfdyvcvdsp 567

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  438 -QLEDTGKQI-VAAQTRLSELHHEIEA-------------AEQKVLRATQEFKQLEEAIRQKKISEAEKDLLLKQLSGRL 502
Cdd:COG4913    568 eELRRHPRAItRAGQVKGNGTRHEKDDrrrirsryvlgfdNRAKLAALEAELAELEEELAEAEERLEALEAELDALQERR 647

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  503 RHLNKLrQEALDLEAQLEKQRKEIAEKHEEINSAQLATDLLdskdpkqshmkaqkRGKEQQLDIMNKQYTQLESRLDEIL 582
Cdd:COG4913    648 EALQRL-AEYSWDEIDVASAEREIAELEAELERLDASSDDL--------------AALEEQLEELEAELEELEEELDELK 712

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  583 CRIATETEEIKDLEQQLTDGQIAANEALKKDLEGVISGLQEYLGTIKGQAAQA------QNECRKLQDEKETLLQRLTEV 656
Cdd:COG4913    713 GEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLEERFAAALGDAVERelrenlEERIDALRARLNRAEEELERA 792

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  657 --------KQEKDELEIVAMDAENMRKELAELEN-ALQEQHE--VNASLQQAQGDLSAYETELETQLKLKDAETSQLKQE 725
Cdd:COG4913    793 mrafnrewPAETADLDADLESLPEYLALLDRLEEdGLPEYEErfKELLNENSIEFVADLLSKLRRAIREIKERIDPLNDS 872

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1958764989  726 LENLV----RRTQLEQSVLQTELEKE-RQSLRDALGKAQSSEEKQQENSelRAQLKQL 778
Cdd:COG4913    873 LKRIPfgpgRYLRLEARPRPDPEVREfRQELRAVTSGASLFDEELSEAR--FAALKRL 928
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 438-800 4.46e-07

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 55.41  E-value: 4.46e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  438 QLEDTGKQIVAAQTRLSELHHEIEAAEQKVLRATQEFKQLEEAIRQKKISEAEKDL---------LLKQLSGRLRHLNKL 508
Cdd:TIGR04523  282 KIKELEKQLNQLKSEISDLNNQKEQDWNKELKSELKNQEKKLEEIQNQISQNNKIIsqlneqisqLKKELTNSESENSEK 361

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  509 RQEALDLEAQLEKQRKEIAEKHEEINSAQLATDLLDSKDPKQshmKAQKRGKEQQLDIMNKQYTQLESRLDEILCRIATE 588
Cdd:TIGR04523  362 QRELEEKQNEIEKLKKENQSYKQEIKNLESQINDLESKIQNQ---EKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKN 438

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  589 TEEIKDLEQqltdgQIAANEALKKDLEGVISGLQEYLGTIKGQAAQAQNECRKLQDEKETLLQRLTEVKQEKDELEIVAM 668
Cdd:TIGR04523  439 NSEIKDLTN-----QDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKELKSKEKELKKLNEEKKELEEKVK 513

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  669 DAENMRKELAELENALQ-EQHEVNASLQQAQGDLSAYETE-----LETQLKLKDAETSQLKQELENLvRRTQLEQSVLQT 742
Cdd:TIGR04523  514 DLTKKISSLKEKIEKLEsEKKEKESKISDLEDELNKDDFElkkenLEKEIDEKNKEIEELKQTQKSL-KKKQEEKQELID 592

                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1958764989  743 ELEKERQSLRDALgkaqssEEKQQENSELRAQLKQLQDDNSLLKKQLKDFQSHLNHVV 800
Cdd:TIGR04523  593 QKEKEKKDLIKEI------EEKEKKISSLEKELEKAKKENEKLSSIIKNIKSKKNKLK 644
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
438-798 4.80e-07

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 55.16  E-value: 4.80e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  438 QLEDTGKQIVAAQTRLSELHHEIEAAEQKVLRATQEFKQLEEAIRQKKISEAEKDL--LLKQLSGRLRHLNKLRQEALDL 515
Cdd:COG4717     82 EAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPLYQELEALeaELAELPERLEELEERLEELREL 161

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  516 EAQLEKQRKEIAEKHEEINSAQLATDLLDSKDPKQ-----SHMKAQKRGKEQQLDIMNKQYTQLESRLDEILCRIATETE 590
Cdd:COG4717    162 EEELEELEAELAELQEELEELLEQLSLATEEELQDlaeelEELQQRLAELEEELEEAQEELEELEEELEQLENELEAAAL 241

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  591 EIKDLEQQLTDGQIAANEALKKDLEGVISGLQEYLGTIKGQAAQAQNECRKLQDEKETLLQRLTEVKQE----------- 659
Cdd:COG4717    242 EERLKEARLLLLIAAALLALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEELQALpaleeleeeel 321

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  660 KDELEIVAMDAENMRKELAELENALQEQHEVNASLQQA--QGDLSAYETELETQLKLKDAET-SQLKQELENLVRRTQLE 736
Cdd:COG4717    322 EELLAALGLPPDLSPEELLELLDRIEELQELLREAEELeeELQLEELEQEIAALLAEAGVEDeEELRAALEQAEEYQELK 401

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1958764989  737 Q--SVLQTELEKERQSLRDALgKAQSSEEKQQENSELRAQLKQLQDDNSLLKKQLKDFQSHLNH 798
Cdd:COG4717    402 EelEELEEQLEELLGELEELL-EALDEEELEEELEELEEELEELEEELEELREELAELEAELEQ 464
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 1484-2134 5.34e-07

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 54.97  E-value: 5.34e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1484 KRAQETALNLVKAEQQLRLLQADAEDLEQHKIKQEEILKEINKVVAAKDADFQCLNEKKEKLTEELQSLQRDIKAAEVNE 1563
Cdd:TIGR00618  163 KEKKELLMNLFPLDQYTQLALMEFAKKKSLHGKAELLTLRSQLLTLCTPCMPDTYHERKQVLEKELKHLREALQQTQQSH 242

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1564 DHHLQVLKESESLLQAKRA--ELETLKSQVTSQQQELAVLDSQLGHRR--EELLLLQDSLTQAK-------ADLQEALTL 1632
Cdd:TIGR00618  243 AYLTQKREAQEEQLKKQQLlkQLRARIEELRAQEAVLEETQERINRARkaAPLAAHIKAVTQIEqqaqrihTELQSKMRS 322

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1633 GETEVAEKCSHIREVKSLLEELSFQKGELNVHISERR-TQLTLIKQEIEKEEENLEVVLQQLSKHKTELKNVADILQLET 1711
Cdd:TIGR00618  323 RAKLLMKRAAHVKQQSSIEEQRRLLQTLHSQEIHIRDaHEVATSIREISCQQHTLTQHIHTLQQQKTTLTQKLQSLCKEL 402

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1712 NELQSLKLQHDQKVVELEKTQVDLLEGKLELESLQQTAQQQRRELERQRQLLERDRRET----ERVRAETQALQSCIECL 1787
Cdd:TIGR00618  403 DILQREQATIDTRTSAFRDLQGQLAHAKKQQELQQRYAELCAAAITCTAQCEKLEKIHLqesaQSLKEREQQLQTKEQIH 482

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1788 NKEKE----------HLQEQCESWEKKSSHAKRVLAATEESNNTeQSKLGQLEVSVRKLQQELE----LLSQDKLALHSD 1853
Cdd:TIGR00618  483 LQETRkkavvlarllELQEEPCPLCGSCIHPNPARQDIDNPGPL-TRRMQRGEQTYAQLETSEEdvyhQLTSERKQRASL 561

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1854 SAQEQ----------QQLQDKREALNSLQKELENTQDHLNlAKQDLMHTTKCQSALLSEQAQLQKDVSQWTARLESCQKE 1923
Cdd:TIGR00618  562 KEQMQeiqqsfsiltQCDNRSKEDIPNLQNITVRLQDLTE-KLSEAEDMLACEQHALLRKLQPEQDLQDVRLHLQQCSQE 640

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1924 TETKE-----QQLQELQDEIRESKLQLDQQEMVF----QKLQKERESEEQKLVASIVSLEQQQ----------------- 1977
Cdd:TIGR00618  641 LALKLtalhaLQLTLTQERVREHALSIRVLPKELlasrQLALQKMQSEKEQLTYWKEMLAQCQtllrelethieeydref 720

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1978 GQLERELMDQKSKLEWLLTDVSAAEGRLRTLQKEERCTESLE-KMLSQAKQQLSEREQQLMEKSGDLLALQKEADGMRAD 2056
Cdd:TIGR00618  721 NEIENASSSLGSDLAAREDALNQSLKELMHQARTVLKARTEAhFNNNEEVTAALQTGAELSHLAAEIQFFNRLREEDTHL 800

                          650       660       670       680       690       700       710
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1958764989 2057 FSLLRNQFLTERKKAEkqvaGLKEALKIQRSQLEKNLLEQKQENSCMQKEMATIELVAQDNHERARRLMKELRQMQQE 2134
Cdd:TIGR00618  801 LKTLEAEIGQEIPSDE----DILNLQCETLVQEEEQFLSRLEEKSATLGEITHQLLKYEECSKQLAQLTQEQAKIIQL 874
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 479-1100 5.85e-07

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 55.07  E-value: 5.85e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  479 EAIRQKKISEAEKDLLLKQLSGRLRHLNKLRQEALDLEA-QLEKQRKEIAEKHEEINSAqlatdlldskDPKQSHMKAQK 557
Cdd:TIGR02169  177 EELEEVEENIERLDLIIDEKRQQLERLRREREKAERYQAlLKEKREYEGYELLKEKEAL----------ERQKEAIERQL 246

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  558 RGKEQQLDIMNKQYTQLESRLDEILCRIATETEEIKDL---EQQLTDGQIAANEALKKDLEGVISGLQEYLGTIKGQAAQ 634
Cdd:TIGR02169  247 ASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLgeeEQLRVKEKIGELEAEIASLERSIAEKERELEDAEERLAK 326

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  635 AQNECRKLQDEKETLLQRLTEVKQEKDEL-EIVAMDAENMRKELAELEnalqeqhEVNASLQQAQGDLSAYETELEtqlK 713
Cdd:TIGR02169  327 LEAEIDKLLAEIEELEREIEEERKRRDKLtEEYAELKEELEDLRAELE-------EVDKEFAETRDELKDYREKLE---K 396

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  714 LKDAetsqlKQELENLVRRTQLEQSVLQTELEKERQSLRDALGK----AQSSEEKQQENSELRAQLKQLQDDNSLLKKQL 789
Cdd:TIGR02169  397 LKRE-----INELKRELDRLQEELQRLSEELADLNAAIAGIEAKinelEEEKEDKALEIKKQEWKLEQLAADLSKYEQEL 471

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  790 KDFQSHLNHVVDGLihpEEVAARVDELRKRLKLGAGEMRIHSP-SDVLGKSLADLQKQFSEILarsqwekeeaqvrerKL 868
Cdd:TIGR02169  472 YDLKEEYDRVEKEL---SKLQRELAEAEAQARASEERVRGGRAvEEVLKASIQGVHGTVAQLG---------------SV 533

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  869 HEEMALQQEKLANGQEEFKQACERALEAR-IKFDKRQHNARIQQLENEIHYLQENLKSMEKIQGLTD--LQLQEADEEKE 945
Cdd:TIGR02169  534 GERYATAIEVAAGNRLNNVVVEDDAVAKEaIELLKRRKAGRATFLPLNKMRDERRDLSILSEDGVIGfaVDLVEFDPKYE 613

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  946 RILAQ-------LQELEKKKRREDarsQEQFLGLDTEL---------KSLKKAVAASDKLA-AAELTIAKEQLKSLHGTV 1008
Cdd:TIGR02169  614 PAFKYvfgdtlvVEDIEAARRLMG---KYRMVTLEGELfeksgamtgGSRAPRGGILFSRSePAELQRLRERLEGLKREL 690

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1009 MRINQERAEELQEAERSSREAMQAAKDLSRAEAEIELLQhllrEREGQFRDEMENahvgsKGANLQLL--EIEALKEAMA 1086
Cdd:TIGR02169  691 SSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLE----QEEEKLKERLEE-----LEEDLSSLeqEIENVKSELK 761

                          650
                   ....*....|....
gi 1958764989 1087 KQRAEITRLRDVLN 1100
Cdd:TIGR02169  762 ELEARIEELEEDLH 775
LRR_8 pfam13855
Leucine rich repeat;
126-181 6.21e-07

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 48.29  E-value: 6.21e-07
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  126 KLEVLNLSYNLIAKIEKV--DKLLRLRELNLSYNKISKIEG--LENMCNLQKLNLAGNEI 181
Cdd:pfam13855    2 NLRSLDLSNNRLTSLDDGafKGLSNLKVLDLSNNLLTTLSPgaFSGLPSLRYLDLSGNRL 61
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
1426-1640 6.39e-07

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 54.64  E-value: 6.39e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1426 LEKTLLKRRSELREADRLLAE--AESELACTKEKTKSAVEKFTDAKRNLLQTESDAEALEKRAQETALNLVKAEQQLRLL 1503
Cdd:COG3206    180 LEEQLPELRKELEEAEAALEEfrQKNGLVDLSEEAKLLLQQLSELESQLAEARAELAEAEARLAALRAQLGSGPDALPEL 259

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1504 QADAE--DLEQHKIKQEEILKEINKVVAAKDADFQCLNEKKEKLTEELQSLQRDIKAAEVNEdhhLQVLKESESLLQAKR 1581
Cdd:COG3206    260 LQSPViqQLRAQLAELEAELAELSARYTPNHPDVIALRAQIAALRAQLQQEAQRILASLEAE---LEALQAREASLQAQL 336

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1958764989 1582 AELETLKSQVTSQQQELAVLDSQLGHRREELLLLQDSLTQAKadLQEALTLGETEVAEK 1640
Cdd:COG3206    337 AQLEARLAELPELEAELRRLEREVEVARELYESLLQRLEEAR--LAEALTVGNVRVIDP 393
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 1424-2141 7.35e-07

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 54.59  E-value: 7.35e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1424 ECLEKTLLKRRSELREADRLLAEAESElactKEKTKSAVEKFTDAKRNLLQTESDAEALEKRAQETALNLVkaEQQLRLL 1503
Cdd:pfam02463  169 RKKKEALKKLIEETENLAELIIDLEEL----KLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLN--EERIDLL 242

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1504 QADAEDLEQHK-------IKQEEILKEINKVVAAKDADFQCLNEKKEKLTEELQSLQRDIKAAEVNEDHHLQVLKESESL 1576
Cdd:pfam02463  243 QELLRDEQEEIesskqeiEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKE 322

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1577 LQAKRAELETLKSQVTSQQQELAVLDSQLGHRREELLLLQDSLTQAKADLQEALTLGETEVAEKCSHIREVKSLLEELSF 1656
Cdd:pfam02463  323 KKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSE 402

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1657 QKGELNVHISERRTQLTLIKQEIEKEEENLEVVLQQLSKHKTELKNVADILQLETNELQSLKLQHDQKVVELEKTQVDLL 1736
Cdd:pfam02463  403 EEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKL 482

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1737 EGKLELES----LQQTAQQQRRELERQRQLLERDRRETERVRAETQALQSCIE-----CLNKEKEHLQEQCESWEKKSSH 1807
Cdd:pfam02463  483 QEQLELLLsrqkLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGvavenYKVAISTAVIVEVSATADEVEE 562

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1808 AKRVLAATEESNNTEQSKLGQLEVSVRKLQQELELLSQDKLALHSDSAQEQQQLQDKREALNSLQKELENTQDHLNLAKQ 1887
Cdd:pfam02463  563 RQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAK 642

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1888 DLMHTTKCQSALLSEQAQLQKD---VSQWTARLESCQKETETKEQQLQEL----QDEIRESKLQLDQQEMVFQKLQKERE 1960
Cdd:pfam02463  643 AKESGLRKGVSLEEGLAEKSEVkasLSELTKELLEIQELQEKAESELAKEeilrRQLEIKKKEQREKEELKKLKLEAEEL 722

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1961 SEEQKLVASIVSLEQQQGQLERELMDQKSKLEWLLTDVSAAEGRLRTLQKEERCTESLEKMLSQAKQQLSEREQQLMEKS 2040
Cdd:pfam02463  723 LADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEE 802

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 2041 gdLLALQKEadgmradfSLLRNQFLTERKKAEKQVAGLKEALKIQRSQLEKNLLEQKQENSCMQKEMATIELVAQDNHER 2120
Cdd:pfam02463  803 --LRALEEE--------LKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQEL 872

                          730       740
                   ....*....|....*....|.
gi 1958764989 2121 ARRLMKELRQMQQEYLELKKQ 2141
Cdd:pfam02463  873 LLKEEELEEQKLKDELESKEE 893
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1540-2135 9.79e-07

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 54.30  E-value: 9.79e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1540 EKKEKLTEELQSLQRDIKAAEVNEDHHLQVLKESESLLQAKRAELETLKSQVTSQQQELAVLDSQLGHRREELLLLqDSL 1619
Cdd:PRK03918   158 DDYENAYKNLGEVIKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKEL-EEL 236

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1620 TQAKADLQEALTLGETEVAEKCSHIREVKSLLEELSFQKGEL--NVHISERRTQLTLIKQEIEKEEENLEVVLQQLSKHK 1697
Cdd:PRK03918   237 KEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELeeKVKELKELKEKAEEYIKLSEFYEEYLDELREIEKRL 316

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1698 TELKNVADILQLETNELQSLKlqhdQKVVELEKTQVDLLEGKLELESLQQTAQQQRRELERQRQLLERDR-RETERVRAE 1776
Cdd:PRK03918   317 SRLEEEINGIEERIKELEEKE----ERLEELKKKLKELEKRLEELEERHELYEEAKAKKEELERLKKRLTgLTPEKLEKE 392

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1777 tqalqscIECLNKEKEHLQEQCESWEKKSSHAKRVLAATEESNNTEQSKLGQLEVSVRKLQQE--LELLSQDKLALhSDS 1854
Cdd:PRK03918   393 -------LEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKAKGKCPVCGRELTEEhrKELLEEYTAEL-KRI 464

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1855 AQEQQQLQDKREALNSLQKELENTqdhlnLAKQDLMHTTKcqsALLSEQAQLQKDVSQWTA-RLESCQKETETKEQQLQE 1933
Cdd:PRK03918   465 EKELKEIEEKERKLRKELRELEKV-----LKKESELIKLK---ELAEQLKELEEKLKKYNLeELEKKAEEYEKLKEKLIK 536

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1934 LQDEIRESKLQLDQQEmvfqKLQKERESEEQKLVASIVSLEQQQGQLERELMDQKSKLEWLLTDVSAAEGRLRTLQKEER 2013
Cdd:PRK03918   537 LKGEIKSLKKELEKLE----ELKKKLAELEKKLDELEEELAELLKELEELGFESVEELEERLKELEPFYNEYLELKDAEK 612

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 2014 CTESLEKMLSQAKQQLSEREQQLMEKSGDLLALQKEADGMRADFSLLRNQFLTERK-KAEKQVAGLK---EALKIQRSQL 2089
Cdd:PRK03918   613 ELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEELEKKYSEEEYEELREEYlELSRELAGLRaelEELEKRREEI 692

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|....*.
gi 1958764989 2090 EKNLLEQKQENSCMQKEMATIELVaqdnhERARRLMKELRQMQQEY 2135
Cdd:PRK03918   693 KKTLEKLKEELEEREKAKKELEKL-----EKALERVEELREKVKKY 733
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
259-703 9.87e-07

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 54.28  E-value: 9.87e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  259 DRQEAFErfslEEIERLEKDLEKKTVETEELKNKQTKFLEEIKHQDKLNKSLKEEAmlqkqscEELESDLNTKKELLKQK 338
Cdd:PRK02224   314 ARREELE----DRDEELRDRLEECRVAAQAHNEEAESLREDADDLEERAEELREEA-------AELESELEEAREAVEDR 382

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  339 TVELTracqkqyELEQEL-----AFYKIDAKFEPLNYYPSEYAEmdkspDESPYIGKSRYKRNMFATETYIVSDAQAVQV 413
Cdd:PRK02224   383 REEIE-------ELEEEIeelreRFGDAPVDLGNAEDFLEELRE-----ERDELREREAELEATLRTARERVEEAEALLE 450

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  414 RKMVPDGGQlrhehaPRAQAPPDVQLEDTGKQIVAAQTRLSELHHEIEAAEQKVLRATQEFKQLEEAIRQKKISEAEKDL 493
Cdd:PRK02224   451 AGKCPECGQ------PVEGSPHVETIEEDRERVEELEAELEDLEEEVEEVEERLERAEDLVEAEDRIERLEERREDLEEL 524

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  494 LLKQLSG---RLRHLNKLRQEALDLEAQLEKQRKEIAEKHEEINSAQLATDLLDSKDP----------KQSHMKAQKRGK 560
Cdd:PRK02224   525 IAERRETieeKRERAEELRERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLAelkeriesleRIRTLLAAIADA 604

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  561 EQQLDIMNKQYTQLESRLDEILCRIATETEEIKDLEQQLTDGQIAANEALKKDLEgvisglqEYLgtikgqaAQAQNECR 640
Cdd:PRK02224   605 EDEIERLREKREALAELNDERRERLAEKRERKRELEAEFDEARIEEAREDKERAE-------EYL-------EQVEEKLD 670

                          410       420       430       440       450       460
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1958764989  641 KLQDEKETLLQRLTEVKQEKDELeivamdaENMRKELAELEN---ALQEQHEVNASLQQAQGDLSA 703
Cdd:PRK02224   671 ELREERDDLQAEIGAVENELEEL-------EELRERREALENrveALEALYDEAEELESMYGDLRA 729
PTZ00121 PTZ00121
MAEBL; Provisional
 1445-2142 1.03e-06

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 54.38  E-value: 1.03e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1445 AEAESELACTKEKTKSAVEKFTDAKRNLLQTESDAEALEKRAQETALNLVKAEQQLRLLQA--DAEDLEQ-HKIKQEEIL 1521
Cdd:PTZ00121  1060 AEAKAHVGQDEGLKPSYKDFDFDAKEDNRADEATEEAFGKAEEAKKTETGKAEEARKAEEAkkKAEDARKaEEARKAEDA 1139

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1522 KEINKVVAAKDADFQCLNEKKE--------KLTEELQSLQRDIKAAEVNEDHHLQVLKESESLLQAKRAELETLKSQVTS 1593
Cdd:PTZ00121  1140 RKAEEARKAEDAKRVEIARKAEdarkaeeaRKAEDAKKAEAARKAEEVRKAEELRKAEDARKAEAARKAEEERKAEEARK 1219

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1594 QQQElavldsqlgHRREELlllqDSLTQAKADLQEAltlgetEVAEKCSHIREVKSLLEELSfqkgelnVHISERRTQLT 1673
Cdd:PTZ00121  1220 AEDA---------KKAEAV----KKAEEAKKDAEEA------KKAEEERNNEEIRKFEEARM-------AHFARRQAAIK 1273

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1674 LIKQEIEKEEENLEVVLQQLSKHKTELKNVADILQLETNELQslKLQHDQKVVELEKTQVDLLEGKLE-----LESLQQT 1748
Cdd:PTZ00121  1274 AEEARKADELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAK--KADEAKKKAEEAKKKADAAKKKAEeakkaAEAAKAE 1351

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1749 AQQQRRELERQRQLLERDRRETERVRAETQALQSCIECLNKEKEhLQEQCESWEKKSSHAKRVLAATEESNNTEQ--SKL 1826
Cdd:PTZ00121  1352 AEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADE-AKKKAEEDKKKADELKKAAAAKKKADEAKKkaEEK 1430

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1827 GQLEVSVRKLQQELELLSQDKLALHSDSAQEQQQLQDKREALNSLQKELENTQDHLNLAKQDLMHTTKCQSALLSEQAQL 1906
Cdd:PTZ00121  1431 KKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKK 1510

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1907 QKDVSQwtaRLESCQKETETKEQQLQELQDEIRESKLQLDQQEMvfqklqkeRESEEQKLVASIVSLEQQQGQLERELMD 1986
Cdd:PTZ00121  1511 KADEAK---KAEEAKKADEAKKAEEAKKADEAKKAEEKKKADEL--------KKAEELKKAEEKKKAEEAKKAEEDKNMA 1579

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1987 QKsklewlltdvSAAEGRlrtlQKEERCTESLEKMLSQAKQQLSEREQQLMEKSGDLLALQKEADgMRADFSLLRNQFLT 2066
Cdd:PTZ00121  1580 LR----------KAEEAK----KAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEE-EKKKVEQLKKKEAE 1644

                          650       660       670       680       690       700       710
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1958764989 2067 ERKKAEkQVAGLKEALKIQRSQLEKNLLEQKQENSCMQKEMATiELVAQDNHERARRLMKELRQMQQEYLELKKQS 2142
Cdd:PTZ00121  1645 EKKKAE-ELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEED-EKKAAEALKKEAEEAKKAEELKKKEAEEKKKA 1718
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 1445-1639 1.07e-06

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 53.30  E-value: 1.07e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1445 AEAESELACTKEKTKSAVEKFTDAKRNLLQTESDAEALEKRAQETALNLVKAEQQLRLLQADAEDLEQHKIKQEEILKE- 1523
Cdd:COG3883     12 AFADPQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGEr 91

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1524 -------------INKVVAAKD-ADF-------QCLNEKKEKLTEELQSLQRDIKAAEVNedhhlqvLKESESLLQAKRA 1582
Cdd:COG3883     92 aralyrsggsvsyLDVLLGSESfSDFldrlsalSKIADADADLLEELKADKAELEAKKAE-------LEAKLAELEALKA 164

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1958764989 1583 ELETLKSQVTSQQQELAVLDSQLGHRREELLLLQDSLTQAKADLQEALTLGETEVAE 1639
Cdd:COG3883    165 ELEAAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAA 221
COG5022 COG5022
Myosin heavy chain [General function prediction only];
1832-2134 1.14e-06

Myosin heavy chain [General function prediction only];


Pssm-ID: 227355 [Multi-domain]  Cd Length: 1463  Bit Score: 54.31  E-value: 1.14e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1832 SVRKLQQELELLSQDKLALHSDSAQEQQQLQDKREALNSLQKELENTQDHLNLAKQDLMHTTKCQSALLSEQAQLQKDVS 1911
Cdd:COG5022    783 LRRLVDYELKWRLFIKLQPLLSLLGSRKEYRSYLACIIKLQKTIKREKKLRETEEVEFSLKAEVLIQKFGRSLKAKKRFS 862

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1912 --QWTARLESCQKETETKEQQLQELQDEIRESK------LQLDQQEMVFQKLQKERESEEQK-LVASIVSLEQ--QQGQL 1980
Cdd:COG5022    863 llKKETIYLQSAQRVELAERQLQELKIDVKSISslklvnLELESEIIELKKSLSSDLIENLEfKTELIARLKKllNNIDL 942

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1981 ERELMDQKSKLEWLLTDVSaAEGRLRTLQKE-ERCTESLEKMLSQAKQQLSERE---QQLMEKSGDLLALQKEADGMRAd 2056
Cdd:COG5022    943 EEGPSIEYVKLPELNKLHE-VESKLKETSEEyEDLLKKSTILVREGNKANSELKnfkKELAELSKQYGALQESTKQLKE- 1020

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1958764989 2057 fsllRNQFLTERKKAEKQVAGLKEALKIQRSqleknllEQKQENSCMQKEMATIELVAQDNHERARRLMKELRQMQQE 2134
Cdd:COG5022   1021 ----LPVEVAELQSASKIISSESTELSILKP-------LQKLKGLLLLENNQLQARYKALKLRRENSLLDDKQLYQLE 1087
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 258-1014 1.40e-06

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 53.82  E-value: 1.40e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  258 QDRQEAFERFSLEEIERLEKDLEKKTVETEELKNKQTKFLEEIKH-QDKLNKSLKEEAMLQKQSCEELESDLNTKKELLK 336
Cdd:pfam02463  267 LAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDdEEKLKESEKEKKKAEKELKKEKEEIEELEKELKE 346

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  337 QKTVELTRACQKQYELEQELAFYKIDAKFeplnyypseyaeMDKSPDESPYIGKSRYKRNMFATETYIVSDAQAVQVRKM 416
Cdd:pfam02463  347 LEIKREAEEEEEEELEKLQEKLEQLEEEL------------LAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLLELA 414

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  417 vpdggQLRHEHAPRAQAPPDVQLEDTGKQIVAAQTRLSELHHEIEAAEQKVLRATQEFKQLEEAIRQKKISEAEKDLLLK 496
Cdd:pfam02463  415 -----RQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELL 489

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  497 QLSGRLRHLNKLRQEALDLEAQLE----------------KQRKEIAEKHEEINSAQLATDLLDSKDPKQSHMKAQKRGK 560
Cdd:pfam02463  490 LSRQKLEERSQKESKARSGLKVLLalikdgvggriisahgRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQKLVRA 569

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  561 EQQLDIMNKQYTQLESRLDEILCRIATETEEIKDLEQQLTDGQIAANEALKKDLE-GVISGLQEYLGTIKGQAAQAQNEC 639
Cdd:pfam02463  570 LTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVvEGILKDTELTKLKESAKAKESGLR 649

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  640 RKLQDEKETLLQRLTEVKQEKDELEIVAMDAENMRKELAELENALQEQHEVNASLQQAQGDLSAYETELETQLKLKDAET 719
Cdd:pfam02463  650 KGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQE 729

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  720 SQLKQELENLVRRTQLEQSVLQTELEKERQSLRDALGKAQSSEEKQQENSELRAQLKQLQDDN-SLLKKQLKDFQSHLNH 798
Cdd:pfam02463  730 AQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKeEKLKAQEEELRALEEE 809

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  799 VVDGLIHPEEVAARVDELRKRLKLGAGEMRIHSPSDVLGKSLADLQKQFSEILARSQWEKEEAQVRERKLHEEMALQ--Q 876
Cdd:pfam02463  810 LKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKLKDelE 889

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  877 EKLANGQEEFKQACERALEARIKFDKRQHNARIQQLENEIHYLQENLKSMEKIQGLTDLQLQEADEEKERILAQLQELEK 956
Cdd:pfam02463  890 SKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKEKEENNKEEEEERNKRLLLAK 969

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1958764989  957 KK--------RREDARSQEQFLGLDTELKSLKkavAASDKLAAAELTIAKEQLKSLHGTVMRINQE 1014
Cdd:pfam02463  970 EElgkvnlmaIEEFEEKEERYNKDELEKERLE---EEKKKLIRAIIEETCQRLKEFLELFVSINKG 1032
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1454-2038 1.40e-06

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 53.77  E-value: 1.40e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1454 TKEKTKSAVEKFTD---AKRNLLQTESDAEALEkRAQETALNLVKAEQQLRLLQADAEDLEQHKIKQEEILKEinKVVAA 1530
Cdd:COG4913    223 TFEAADALVEHFDDlerAHEALEDAREQIELLE-PIRELAERYAAARERLAELEYLRAALRLWFAQRRLELLE--AELEE 299

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1531 KDADFQCLNEKKEKLTEELQSLQRDIKAAEVN-EDHHLQVLKESESLLQAKRAELETLKSQVTSQQQELAVLDSQLGHRR 1609
Cdd:COG4913    300 LRAELARLEAELERLEARLDALREELDELEAQiRGNGGDRLEQLEREIERLERELEERERRRARLEALLAALGLPLPASA 379

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1610 EELLLLQ-------DSLTQAKADLQEALTLGETEVAEKCSHIREVKSLLEELSFQKGELNVHISERRTQLtlikqeieke 1682
Cdd:COG4913    380 EEFAALRaeaaallEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKSNIPARLLALRDAL---------- 449

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1683 eenlevvLQQLSKHKTELKNVADILQLETNE----------------------------------------LQSLKLQHD 1722
Cdd:COG4913    450 -------AEALGLDEAELPFVGELIEVRPEEerwrgaiervlggfaltllvppehyaaalrwvnrlhlrgrLVYERVRTG 522

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1723 QKVVELEKTQVDLLEGKLELES---------------------------------------------------------- 1744
Cdd:COG4913    523 LPDPERPRLDPDSLAGKLDFKPhpfrawleaelgrrfdyvcvdspeelrrhpraitragqvkgngtrhekddrrrirsry 602

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1745 -LQQTAQQQRRELERQRQLLERDRRETERVRAEtqalqsciecLNKEKEHLQEQCESWEKKSSHAkrvlaateesnnTEQ 1823
Cdd:COG4913    603 vLGFDNRAKLAALEAELAELEEELAEAEERLEA----------LEAELDALQERREALQRLAEYS------------WDE 660

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1824 SKLGQLEVSVRKLQQELELLSQDklalHSDSAQEQQQLQDKREALNSLQKELEntqdhlnlakqdlmhttkcqsALLSEQ 1903
Cdd:COG4913    661 IDVASAEREIAELEAELERLDAS----SDDLAALEEQLEELEAELEELEEELD---------------------ELKGEI 715

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1904 AQLQKdvsqwtaRLESCQKETETKEQQLQELQDEIRESkLQLDQQEMVFQKLQKERESEEQK-LVASIVSLEQQQGQLER 1982
Cdd:COG4913    716 GRLEK-------ELEQAEEELDELQDRLEAAEDLARLE-LRALLEERFAAALGDAVERELREnLEERIDALRARLNRAEE 787

                          650       660       670       680       690       700
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1958764989 1983 ELMDQKS--KLEW------LLTDVSAAEG---RLRTLQKEErctesLEKMLSQAKQQLSEREQQLME 2038
Cdd:COG4913    788 ELERAMRafNREWpaetadLDADLESLPEylaLLDRLEEDG-----LPEYEERFKELLNENSIEFVA 849
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1321-1780 1.44e-06

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 53.79  E-value: 1.44e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1321 RDLENEVSRLEDITHHLKSKHQEERWLKTSRQHPEKEVEELHRNIDDLVQEKKELELE-VEELHRTVERHQQRRDFIDGN 1399
Cdd:COG1196    302 QDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAElAEAEEALLEAEAELAEAEEEL 381

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1400 VENLMTELEIEKSLKHHEDIVDEIECLEKTLLKRRSELREADRLLAEAESELACTKEKTKSAVEKFTDAKRNLLQTESDA 1479
Cdd:COG1196    382 EELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEAL 461

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1480 EALEKRAQETALNLVKAEQQLRLLQADAEDLEQHKIKQEEILKEINKVVAAKDadfqcLNEKKEKLTEELQSLQRDIKAA 1559
Cdd:COG1196    462 LELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAAL-----LLAGLRGLAGAVAVLIGVEAAY 536

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1560 EVNEDHHLQVLkesesLLQAKRAELETLKSQVTSQQQELAVLDSQLGHRREELLLLQDSLTQAKADLQEALTLGETEVAE 1639
Cdd:COG1196    537 EAALEAALAAA-----LQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREA 611

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1640 KCSHIREVKSLLEELSFQKGELNVHISERRTQLTLikqeiEKEEENLEVVLQQLSKHKTELKNVADILQLETNELQSLKL 1719
Cdd:COG1196    612 DARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRL-----REVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAE 686

                          410       420       430       440       450       460
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1958764989 1720 QHDQKVVELEKTQVDLLEGKLELESLQQTAQQQRRELERQRQLLERDRRETERVRAETQAL 1780
Cdd:COG1196    687 RLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEEL 747
mukB PRK04863
chromosome partition protein MukB;
445-783 1.49e-06

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 53.81  E-value: 1.49e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  445 QIVAAQTRLSELHHEIEAAEQKVLRATQEFKQLEEAIrqkkiseaekdLLLKQLSGRlrhLNKLRQEALDleaqlekqrK 524
Cdd:PRK04863   838 ELRQLNRRRVELERALADHESQEQQQRSQLEQAKEGL-----------SALNRLLPR---LNLLADETLA---------D 894

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  525 EIAEKHEEINSAQLATDLLDSKDPKQSHMKAQK---RGKEQQLDIMNKQYTQLESRLDEILCRIATETEEIK-------- 593
Cdd:PRK04863   895 RVEEIREQLDEAEEAKRFVQQHGNALAQLEPIVsvlQSDPEQFEQLKQDYQQAQQTQRDAKQQAFALTEVVQrrahfsye 974

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  594 DLEQQLTDGQiAANEALKKDLEgvisGLQEYLGTIKGQAAQAQNECRK-------LQDEKETLLQRLTEVKQEKDELEIV 666
Cdd:PRK04863   975 DAAEMLAKNS-DLNEKLRQRLE----QAEQERTRAREQLRQAQAQLAQynqvlasLKSSYDAKRQMLQELKQELQDLGVP 1049

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  667 AmdAENMRKELA----ELENALQEQHEVNASLQQAQGDLSAYETELETQLKLKDAETSQLKQELEN----------LVRR 732
Cdd:PRK04863  1050 A--DSGAEERARarrdELHARLSANRSRRNQLEKQLTFCEAEMDNLTKKLRKLERDYHEMREQVVNakagwcavlrLVKD 1127

                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|..
gi 1958764989  733 TQLEQSVLQTEL-EKERQSLRDALGKAQSSEEKQQENSELRAQLKQLQDDNS 783
Cdd:PRK04863  1128 NGVERRLHRRELaYLSADELRSMSDKALGALRLAVADNEHLRDVLRLSEDPK 1179
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1440-1654 1.64e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 52.84  E-value: 1.64e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1440 ADRLLAEAESELACTKEKTKSAVEKFTDAKRNLLQTESDAEALEKRAQETALNLVKAEQQLRLLQADAEDLEQHKIKQEE 1519
Cdd:COG4942     18 QADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRA 97

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1520 ILKEINKVVAAK-DADFQCLNEKKEKLTEELQSLQRDIKAAEVNEdHHLQVLKESESLLQAKRAELETLKSQVTSQQQEL 1598
Cdd:COG4942     98 ELEAQKEELAELlRALYRLGRQPPLALLLSPEDFLDAVRRLQYLK-YLAPARREQAEELRADLAELAALRAELEAERAEL 176

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1958764989 1599 AVLDSQLGHRREELLLLQDSLTQAKADLQEALTLGETEVAEKCSHIREVKSLLEEL 1654
Cdd:COG4942    177 EALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARL 232
mukB PRK04863
chromosome partition protein MukB;
1812-2143 1.82e-06

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 53.42  E-value: 1.82e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1812 LAATEESNNTEQSKLGQLEVSVRKLQQELELLSQD-----KLALHSDSAQEQQQLQDKR-EALNSLQKELENTQDHLNLA 1885
Cdd:PRK04863   788 IEQLRAEREELAERYATLSFDVQKLQRLHQAFSRFigshlAVAFEADPEAELRQLNRRRvELERALADHESQEQQQRSQL 867

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1886 KQdlmhtTKCQSALLSE---QAQLQKDvsqwtarlESCQKETETKEQQLQELQDE---IRESKLQLDQQEMVFQKLQKER 1959
Cdd:PRK04863   868 EQ-----AKEGLSALNRllpRLNLLAD--------ETLADRVEEIREQLDEAEEAkrfVQQHGNALAQLEPIVSVLQSDP 934

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1960 ESEEQkLVASIVSLEQQQGQLER------ELMDQKSKLEW-----LLTDVSAAEGRLRTLQKEerctesLEKMLSQAKQQ 2028
Cdd:PRK04863   935 EQFEQ-LKQDYQQAQQTQRDAKQqafaltEVVQRRAHFSYedaaeMLAKNSDLNEKLRQRLEQ------AEQERTRAREQ 1007

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 2029 LSEREQQLMEKSGDLLALQKEADGMRAdfslLRNQFLTERKKAEKQV-AGLKEALKIQRSQLEKNLLEQKQENSCMQKEM 2107
Cdd:PRK04863  1008 LRQAQAQLAQYNQVLASLKSSYDAKRQ----MLQELKQELQDLGVPAdSGAEERARARRDELHARLSANRSRRNQLEKQL 1083

                          330       340       350
                   ....*....|....*....|....*....|....*.
gi 1958764989 2108 ATIELVAQDNHERARRLMKELRQMqQEYLELKKQSW 2143
Cdd:PRK04863  1084 TFCEAEMDNLTKKLRKLERDYHEM-REQVVNAKAGW 1118
PRK11281 PRK11281
mechanosensitive channel MscK;
573-789 2.01e-06

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 53.38  E-value: 2.01e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  573 QLESRLDEILCRIATETEE---IKDLEQQL-----TDGQIAANEALKKDLEGVISGLQEY---LGTIKGQAAQAQNE--- 638
Cdd:PRK11281    40 DVQAQLDALNKQKLLEAEDklvQQDLEQTLalldkIDRQKEETEQLKQQLAQAPAKLRQAqaeLEALKDDNDEETREtls 119

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  639 ---CRKLQDEKETLLQRLTEVKQEKDELEIVAMDAENmRKELA--ELENALQEQHEVNASL---QQAQGDLSAYE-TELE 709
Cdd:PRK11281   120 tlsLRQLESRLAQTLDQLQNAQNDLAEYNSQLVSLQT-QPERAqaALYANSQRLQQIRNLLkggKVGGKALRPSQrVLLQ 198

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  710 TQLKLKDAETSQLKQELENLVRRTQLEQSVL------QTELEKERQSLRDALG--KAQSSEE--KQQENSELRAQLKQlq 779
Cdd:PRK11281   199 AEQALLNAQNDLQRKSLEGNTQLQDLLQKQRdyltarIQRLEHQLQLLQEAINskRLTLSEKtvQEAQSQDEAARIQA-- 276

                          250
                   ....*....|
gi 1958764989  780 ddNSLLKKQL 789
Cdd:PRK11281   277 --NPLVAQEL 284
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 539-770 2.17e-06

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 52.52  E-value: 2.17e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  539 ATDLLDSKDPKQSHMKAQKRGKEQQLDIMNKQYTQLESRLDEILCRIATETEEIKDLEQQLTDGQiAANEALKKDLEGVI 618
Cdd:COG3883     14 ADPQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAE-AEIEERREELGERA 92

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  619 SGLQEYLGTIKGQAA--QAQNecrkLQD--EKETLLQRLTEvkQEKDELEIVAMDAENMRKELAELENALQEQHEVNASL 694
Cdd:COG3883     93 RALYRSGGSVSYLDVllGSES----FSDflDRLSALSKIAD--ADADLLEELKADKAELEAKKAELEAKLAELEALKAEL 166

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1958764989  695 QQAQGDLSAYETELETQLKLKDAETSQLKQELENLVRRTQLEQSVLQTELEKERQSLRDALGKAQSSEEKQQENSE 770
Cdd:COG3883    167 EAAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA 242
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 1805-1990 2.41e-06

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 52.14  E-value: 2.41e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1805 SSHAKRVLAATEESNNTEQSKLGQLEVSVRKLQQELELLSQDKLALHSDSAQEQQQLQDKREALNSLQKELENTQDHL-N 1883
Cdd:COG3883     11 PAFADPQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELgE 90

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1884 LAK---------------------QDLMHTTKCQSALLSEQAQLQKDVSQWTARLESCQKETETKEQQLQELQDEIRESK 1942
Cdd:COG3883     91 RARalyrsggsvsyldvllgsesfSDFLDRLSALSKIADADADLLEELKADKAELEAKKAELEAKLAELEALKAELEAAK 170

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*...
gi 1958764989 1943 LQLDQQEMVFQKLQKERESEEQKLVASIVSLEQQQGQLERELMDQKSK 1990
Cdd:COG3883    171 AELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAA 218
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1405-1756 2.41e-06

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 52.72  E-value: 2.41e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1405 TELEIEKSLKHHEDIVDEIECLEKTLLKRRSELREADRLLAEAESELACTKEKTKSAVEKFTDAKRNLLQTESDAEALEK 1484
Cdd:TIGR04523  326 IQNQISQNNKIISQLNEQISQLKKELTNSESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLESQINDLESKIQNQEK 405

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1485 RAQETALNLVKAEQQLRLLQADAEDLEQHKIKQEEILKEINKVVAAKDADFQCLNEKKEKLTEELQSLQRDIKAAEVNED 1564
Cdd:TIGR04523  406 LNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQNLE 485

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1565 HHLQVLKESESllqakraELETLKSQVTSQQQELAVLDSQlghrreellllQDSLTQAKADLqealtlgETEVAEKCSHI 1644
Cdd:TIGR04523  486 QKQKELKSKEK-------ELKKLNEEKKELEEKVKDLTKK-----------ISSLKEKIEKL-------ESEKKEKESKI 540

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1645 REVKSLLEELSFQKGELNV-----HISERRTQLTLIKQEIEKEEENLEVVLQQLSKHKTELKNvadilQLETNELQSLKL 1719
Cdd:TIGR04523  541 SDLEDELNKDDFELKKENLekeidEKNKEIEELKQTQKSLKKKQEEKQELIDQKEKEKKDLIK-----EIEEKEKKISSL 615

                          330       340       350
                   ....*....|....*....|....*....|....*....
gi 1958764989 1720 QHDQKVVELEKTQVDLLEGKLE--LESLQQTAQQQRREL 1756
Cdd:TIGR04523  616 EKELEKAKKENEKLSSIIKNIKskKNKLKQEVKQIKETI 654
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 261-1105 2.54e-06

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 52.81  E-value: 2.54e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  261 QEAFERFsLEEIERLEKDLEKKTVETEELKNKQTKFLEE--IKHQDKLNK-SLKEEAML-----QKQSCEELESDL-NTK 331
Cdd:pfam15921   73 KEHIERV-LEEYSHQVKDLQRRLNESNELHEKQKFYLRQsvIDLQTKLQEmQMERDAMAdirrrESQSQEDLRNQLqNTV 151

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  332 KELLKQKTVELTRACQKQYELEQelaFYKIDAKFEP-LNYYPSEYAEMDKSPdespyiGKSRYKRNMFATetyivsdaqa 410
Cdd:pfam15921  152 HELEAAKCLKEDMLEDSNTQIEQ---LRKMMLSHEGvLQEIRSILVDFEEAS------GKKIYEHDSMST---------- 212

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  411 VQVRKMVPDGGQLRHEHapraqappDVQLEDTGKQIVAAQTRLSELHHEIEAAEQKVLRATQEfkQLEEAIRQKKIseae 490
Cdd:pfam15921  213 MHFRSLGSAISKILREL--------DTEISYLKGRIFPVEDQLEALKSESQNKIELLLQQHQD--RIEQLISEHEV---- 278

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  491 kdlllkQLSGRLRHLNKLRQEALDLEAQLEKQrKEIAEKHEEINSAQLaTDLLDSKDPKQSHMKAQKRGKEQQLDIMNKQ 570
Cdd:pfam15921  279 ------EITGLTEKASSARSQANSIQSQLEII-QEQARNQNSMYMRQL-SDLESTVSQLRSELREAKRMYEDKIEELEKQ 350

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  571 YTQLESRLDEILCRIATETEEIKDLEQQLTDgQIAANEALKKDLEGVISGLQEYLGTIKGQAAQAQNECRKLQDEK---- 646
Cdd:pfam15921  351 LVLANSELTEARTERDQFSQESGNLDDQLQK-LLADLHKREKELSLEKEQNKRLWDRDTGNSITIDHLRRELDDRNmevq 429

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  647 --ETLLQRLTEVKQEKDELEIVAMDAENMRKE-LAELENALQEQHEVnasLQQAQGDLSAYETELETQLKLKDAETSQLk 723
Cdd:pfam15921  430 rlEALLKAMKSECQGQMERQMAAIQGKNESLEkVSSLTAQLESTKEM---LRKVVEELTAKKMTLESSERTVSDLTASL- 505

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  724 QELENLVRRTQLEQSVLQTELEKERQSLRDALGKAQSSEEKQQENSELRAQLKQLQDDNSLLKKQLKDFQshlnhvvdgl 803
Cdd:pfam15921  506 QEKERAIEATNAEITKLRSRVDLKLQELQHLKNEGDHLRNVQTECEALKLQMAEKDKVIEILRQQIENMT---------- 575

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  804 ihpeevaarvdELRKRLKLGAGEMRIHSPSdvLGKSLADLQKQFSEIlaRSQWEKEEAQVRERKLH-EEMALQQEKLANG 882
Cdd:pfam15921  576 -----------QLVGQHGRTAGAMQVEKAQ--LEKEINDRRLELQEF--KILKDKKDAKIRELEARvSDLELEKVKLVNA 640

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  883 QEEFKQACERALEARIKFDKRQHNAR--IQQLENEIHYLQENLKS----MEKIQGLTDLQLQEADEEKERILAQLQELEK 956
Cdd:pfam15921  641 GSERLRAVKDIKQERDQLLNEVKTSRneLNSLSEDYEVLKRNFRNkseeMETTTNKLKMQLKSAQSELEQTRNTLKSMEG 720

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  957 KkrreDARSQEQFLGLDTELKSLKKAVAAsdklaaaeltiAKEQLKSLHGTVMRINQERAEELQEAERSSREAMQAAKDL 1036
Cdd:pfam15921  721 S----DGHAMKVAMGMQKQITAKRGQIDA-----------LQSKIQFLEEAMTNANKEKHFLKEEKNKLSQELSTVATEK 785

                          810       820       830       840       850       860       870
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1958764989 1037 SRAEAEIELLqhllREREGQFRDEMENAHVGSKGANLQLLEIEalkEAMAKQRAEITRLR-----DVLNLTGTG 1105
Cdd:pfam15921  786 NKMAGELEVL----RSQERRLKEKVANMEVALDKASLQFAECQ---DIIQRQEQESVRLKlqhtlDVKELQGPG 852
mukB PRK04863
chromosome partition protein MukB;
1741-2029 2.60e-06

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 53.04  E-value: 2.60e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1741 ELESLQQTAQQQRRELERQRQLLERDRRETERVRAETQALQSCI--------ECLNKEKEHLQEQCESWEKksshAKRVL 1812
Cdd:PRK04863   838 ELRQLNRRRVELERALADHESQEQQQRSQLEQAKEGLSALNRLLprlnlladETLADRVEEIREQLDEAEE----AKRFV 913

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1813 AAteesnntEQSKLGQLEVSVRKLQ---QELELLSQDklalHSDSAQEQQQLQDKREALnslqKELENTQDHLNLAKQdl 1889
Cdd:PRK04863   914 QQ-------HGNALAQLEPIVSVLQsdpEQFEQLKQD----YQQAQQTQRDAKQQAFAL----TEVVQRRAHFSYEDA-- 976

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1890 mhttkcqSALLSEQAQLqkdVSQWTARLEScqketetKEQQLQELQDEIRESKLQLDQQEMVFQKLQKERESEEQKLVAS 1969
Cdd:PRK04863   977 -------AEMLAKNSDL---NEKLRQRLEQ-------AEQERTRAREQLRQAQAQLAQYNQVLASLKSSYDAKRQMLQEL 1039

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1958764989 1970 IVSLEQ---------------QQGQLERELMDQKSKLEWLLTDVSAAEGRLRTLQKEERcteSLEKMLSQAKQQL 2029
Cdd:PRK04863  1040 KQELQDlgvpadsgaeeraraRRDELHARLSANRSRRNQLEKQLTFCEAEMDNLTKKLR---KLERDYHEMREQV 1111
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1539-1792 2.90e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 52.07  E-value: 2.90e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1539 NEKKEKLTEELQSLQRDIKAAEVNEDHHLQVLKESESLLQAKRAELETLKSQVTSQQQELAVLDSQLGHRREELLLLQDS 1618
Cdd:COG4942     19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAE 98

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1619 LTQAKADLQEALTlgeteVAEKCSHIREVKSLLEELSFQKgelnvhiSERRTQLtlikqeiekeeenlevvLQQLSKhkt 1698
Cdd:COG4942     99 LEAQKEELAELLR-----ALYRLGRQPPLALLLSPEDFLD-------AVRRLQY-----------------LKYLAP--- 146

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1699 ELKNVADILQLETNELQSLKLQHDQKVVELEKTQVDLLEGKLELESLQQTAQQQRRELERQrqlLERDRRETERVRAETQ 1778
Cdd:COG4942    147 ARREQAEELRADLAELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKE---LAELAAELAELQQEAE 223

                          250
                   ....*....|....
gi 1958764989 1779 ALQSCIECLNKEKE 1792
Cdd:COG4942    224 ELEALIARLEAEAA 237
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1421-1640 2.95e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 52.07  E-value: 2.95e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1421 DEIECLEKTLLKRRSELREADRLLAEAESELACTKEKTKSAVEKFTDAKRNLLQTESDAEALEKRAQETALNLVKAEQQL 1500
Cdd:COG4942     20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAEL 99

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1501 RLLQADAEDL--EQHKIKQEEILKEINKVVAAKDA--DFQCLNEKKEKLTEELQSLQRDIKAAEVNEDHHLQVLKESESL 1576
Cdd:COG4942    100 EAQKEELAELlrALYRLGRQPPLALLLSPEDFLDAvrRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEAL 179

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1958764989 1577 LQAKRAELETLKSQVTSQQQELAVLDSQLGHRREELLLLQdsltQAKADLQEALTLGETEVAEK 1640
Cdd:COG4942    180 LAELEEERAALEALKAERQKLLARLEKELAELAAELAELQ----QEAEELEALIARLEAEAAAA 239
46 PHA02562
endonuclease subunit; Provisional
 473-667 3.49e-06

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 52.32  E-value: 3.49e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  473 EFKQLEEAIRQKkISEAEKDL--LLKQLSGRLRHLNKLRQEALDLEAQLEKQRKEIaEKHEEINSAQLATDLLDSKDPKQ 550
Cdd:PHA02562   224 ELVEEAKTIKAE-IEELTDELlnLVMDIEDPSAALNKLNTAAAKIKSKIEQFQKVI-KMYEKGGVCPTCTQQISEGPDRI 301

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  551 SHMKAQKRGKEQQLDIMNKQYTQLESRLDEILCRIATETEEIKDLEQQltDGQIAANEALKKDLEGVISGLQEYLGTIKG 630
Cdd:PHA02562   302 TKIKDKLKELQHSLEKLDTAIDELEEIMDEFNEQSKKLLELKNKISTN--KQSLITLVDKAKKVKAAIEELQAEFVDNAE 379

                          170       180       190
                   ....*....|....*....|....*....|....*..
gi 1958764989  631 qaaqaqnECRKLQDEKETLLQRLTEVKQEKDELEIVA 667
Cdd:PHA02562   380 -------ELAKLQDELDKIVKTKSELVKEKYHRGIVT 409
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 514-964 3.84e-06

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 52.36  E-value: 3.84e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  514 DLEAQLEKQRKEIAEKHEEINSAQLATDLLDSkdpkqshMKAQKRGKEQQLDIMNKQYTQLESRLDEILCRIATETEEIK 593
Cdd:TIGR00606  636 DEESDLERLKEEIEKSSKQRAMLAGATAVYSQ-------FITQLTDENQSCCPVCQRVFQTEAELQEFISDLQSKLRLAP 708

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  594 DlEQQLTDGQIAANEALKKDLEGVISGLQEYLGTIKGQAAQAQNECRKLQDEKETLLQRLTE-------VKQEKDELEIV 666
Cdd:TIGR00606  709 D-KLKSTESELKKKEKRRDEMLGLAPGRQSIIDLKEKEIPELRNKLQKVNRDIQRLKNDIEEqetllgtIMPEEESAKVC 787

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  667 AMDAENMRKELAELENALQEQHEVNASLQQAQGDLSAyeTELETQLKLKDAETSQLKQELENLVRRTQLEQSVLQ----- 741
Cdd:TIGR00606  788 LTDVTIMERFQMELKDVERKIAQQAAKLQGSDLDRTV--QQVNQEKQEKQHELDTVVSKIELNRKLIQDQQEQIQhlksk 865

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  742 -TELEKERQSLRDALGKAQS----SEEKQQENSELRAQLKQLQDDNSLLKKQLKDFQSHLNHVVDGLIHPEEVAA-RVDE 815
Cdd:TIGR00606  866 tNELKSEKLQIGTNLQRRQQfeeqLVELSTEVQSLIREIKDAKEQDSPLETFLEKDQQEKEELISSKETSNKKAQdKVND 945

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  816 LRKRLKLGAGEMRihSPSDVLGKSLADLQKQFSEILARSQWEKEEAQVRERKLHEEMALQQEKLANGQEEFK----QACE 891
Cdd:TIGR00606  946 IKEKVKNIHGYMK--DIENKIQDGKDDYLKQKETELNTVNAQLEECEKHQEKINEDMRLMRQDIDTQKIQERwlqdNLTL 1023

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  892 RALEARIK--------FDKRQHNARIQQLENEIHYLQENLKSMEKIQGLTDLQLQEADEEKERILAQLQELEKKKRREDA 963
Cdd:TIGR00606 1024 RKRENELKeveeelkqHLKEMGQMQVLQMKQEHQKLEENIDLIKRNHVLALGRQKGYEKEIKHFKKELREPQFRDAEEKY 1103


                   .
gi 1958764989  964 R 964
Cdd:TIGR00606 1104 R 1104
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1476-1804 3.87e-06

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 52.38  E-value: 3.87e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1476 ESDAEALEKRAQETALNLVKAEQQLRLLQADAEDLEQHKIKQEEILKEINKVVAAKDADFQCLNEKKEKLTEELQSLQRD 1555
Cdd:TIGR02169  666 ILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEED 745

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1556 IKAAEV---NEDHHLQVL-----------------------KESESLLQAKRAELETLKSQVTSQQQELAVLDSQLGHR- 1608
Cdd:TIGR02169  746 LSSLEQeieNVKSELKELearieeleedlhkleealndleaRLSHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLt 825

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1609 ---------REELLLLQDSLTQAKADLQEALTLGETEVAEKCSHIREVKSLLEELSFQKGELNVHISERRTQltlikqei 1679
Cdd:TIGR02169  826 lekeylekeIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQ-------- 897

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1680 ekeeenlevvLQQLSKHKTELKNVADILQLETNELQSLKLQHDQKVVELEKTQVDLLEGKLELESLQQTaQQQRRELERQ 1759
Cdd:TIGR02169  898 ----------LRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEELSLEDV-QAELQRVEEE 966

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|....*....
gi 1958764989 1760 RQLLE----RDRRETERVRAETQALQSCIECLNKEKEHLQEQCESWEKK 1804
Cdd:TIGR02169  967 IRALEpvnmLAIQEYEEVLKRLDELKEKRAKLEEERKAILERIEEYEKK 1015
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1322-1802 3.92e-06

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 52.35  E-value: 3.92e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1322 DLENEVSRLEDITHHLKSKHQEERWLKTSRQ-----HPEK--EVEELHRNIDDLVQEKKELELEVEELHRTVERHQQRRD 1394
Cdd:PRK02224   210 GLESELAELDEEIERYEEQREQARETRDEADevleeHEERreELETLEAEIEDLRETIAETEREREELAEEVRDLRERLE 289

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1395 FIDGNVENLMTELEIEKSlkHHEDIVDEIECLEktllKRRSELREAdrlLAEAESELACTKEKTKSAVEKFTDAKRNLLQ 1474
Cdd:PRK02224   290 ELEEERDDLLAEAGLDDA--DAEAVEARREELE----DRDEELRDR---LEECRVAAQAHNEEAESLREDADDLEERAEE 360

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1475 TESDAEALEKRAQETALNLVKAEQQLRLLQADAEDLEQHKIKQEEILKEINKVVAAKDADFQCLNEKKEKLTEELQSLQR 1554
Cdd:PRK02224   361 LREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREERDELREREAELEATLRTARE 440

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1555 DIKAAE--------------VNEDHHLQVLKESESLLQAKRAELETLKSQVTSQQQELAvldsqlghRREELLLLQDSLT 1620
Cdd:PRK02224   441 RVEEAEalleagkcpecgqpVEGSPHVETIEEDRERVEELEAELEDLEEEVEEVEERLE--------RAEDLVEAEDRIE 512

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1621 qakaDLQEALTLGETEVAEKCSHIREVKSLLEELSFQKGELNVHISERRTQLTLIKQEIEKEEENLEVVLQQLSKHKTE- 1699
Cdd:PRK02224   513 ----RLEERREDLEELIAERRETIEEKRERAEELRERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLAELKERi 588

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1700 --LKNVADILQLETN---ELQSL--KLQHDQKVVELEKTQV-DLLEGKLELESLQQTA--QQQRRELERQRQLLERDRRE 1769
Cdd:PRK02224   589 esLERIRTLLAAIADaedEIERLreKREALAELNDERRERLaEKRERKRELEAEFDEAriEEAREDKERAEEYLEQVEEK 668

                          490       500       510       520
                   ....*....|....*....|....*....|....*....|...
gi 1958764989 1770 TERVRAETQALQSCI----------ECLNKEKEHLQEQCESWE 1802
Cdd:PRK02224   669 LDELREERDDLQAEIgaveneleelEELRERREALENRVEALE 711
Drf_FH1 pfam06346
Formin Homology Region 1; This region is found in some of the Diaphanous related formins (Drfs) ...
 1238-1300 4.77e-06

Formin Homology Region 1; This region is found in some of the Diaphanous related formins (Drfs). It consists of low complexity repeats of around 12 residues.


Pssm-ID: 461881 [Multi-domain]  Cd Length: 157  Bit Score: 48.71  E-value: 4.77e-06
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1958764989 1238 PPFVPPPGYIMYTVLPDGSPVPqgvalyaPSPPLPHSSH----PLTPGTVVYGPPPA--GAPIIYGPPP 1300
Cdd:pfam06346    1 PPPPPLPGDSSTIPLPPGACIP-------TPPPLPGGGGppppPPLPGSAAIPPPPPlpGGTSIPPPPP 62
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
448-921 4.88e-06

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 51.96  E-value: 4.88e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  448 AAQTRLSELHHEIEAAEQKVLRAT-----------------QEFKQLEEAIR--QKKISEAEKDllLKQLSGRLRhlnKL 508
Cdd:PRK02224   210 GLESELAELDEEIERYEEQREQARetrdeadevleeheerrEELETLEAEIEdlRETIAETERE--REELAEEVR---DL 284

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  509 RQEALDLEAQLEKQRKEIAEKHEEINSAQLATDLLDSKDPKQSHMKAQKRGKEQQLdimNKQYTQLESRLDEILCRIATE 588
Cdd:PRK02224   285 RERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRDRLEECRVAAQAH---NEEAESLREDADDLEERAEEL 361

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  589 TEEIKDLEQQLTDGQIAANEAlkkdlEGVISGLQEYLGTIKGQAAQAQNECRKLQDEKETLLQRLTEVKQEKDELEIVAM 668
Cdd:PRK02224   362 REEAAELESELEEAREAVEDR-----REEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREERDELREREAELEATLR 436

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  669 DAENMRKELAEL----------------------ENALQEQHEVNASLQQAQGDLSAYETELETQLKLKDAET--SQLKQ 724
Cdd:PRK02224   437 TARERVEEAEALleagkcpecgqpvegsphvetiEEDRERVEELEAELEDLEEEVEEVEERLERAEDLVEAEDriERLEE 516

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  725 ELENLV-----RRTQLEQSVLQ-TELEKERQSLR-DALGKAQSSEEKQQENSELRAQLKQLQDDnsllKKQLKDFQSHLN 797
Cdd:PRK02224   517 RREDLEeliaeRRETIEEKRERaEELRERAAELEaEAEEKREAAAEAEEEAEEAREEVAELNSK----LAELKERIESLE 592

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  798 HVVDGLIHPEEVAARVDELRKRLklgagemrihspsdvlgKSLADLQKQFSEILArsqwEKEEaqvRERKLHEE-----M 872
Cdd:PRK02224   593 RIRTLLAAIADAEDEIERLREKR-----------------EALAELNDERRERLA----EKRE---RKRELEAEfdearI 648

                          490       500       510       520
                   ....*....|....*....|....*....|....*....|....*....
gi 1958764989  873 ALQQEKLANGQEEFKQACERALEARIKFDKRQhnARIQQLENEIHYLQE 921
Cdd:PRK02224   649 EEAREDKERAEEYLEQVEEKLDELREERDDLQ--AEIGAVENELEELEE 695
RNA1 COG5238
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ...
 85-235 5.13e-06

Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];


Pssm-ID: 444072 [Multi-domain]  Cd Length: 434  Bit Score: 51.33  E-value: 5.13e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989   85 EALIKKLTKQDNlalVKSLNLSLSKDGGKKFRYI-ENLEKCVKLEVLNLSYNLI------AKIEKVDKLLRLRELNLSYN 157
Cdd:COG5238    254 IALAEALKNNTT---VETLYLSGNQIGAEGAIALaKALQGNTTLTSLDLSVNRIgdegaiALAEGLQGNKTLHTLNLAYN 330

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  158 KISK------IEGLENMCNLQKLNLAGNEI---------EHIPGWfskklKSLRVLNLKGNKISSLQDVSKLKPLQ--DL 220
Cdd:COG5238    331 GIGAqgaialAKALQENTTLHSLDLSDNQIgdegaialaKYLEGN-----TTLRELNLGKNNIGKQGAEALIDALQtnRL 405

                          170
                   ....*....|....*
gi 1958764989  221 TSLTLIDNPVVALPH 235
Cdd:COG5238    406 HTLILDGNLIGAEAQ 420
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1527-1779 5.43e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 50.92  E-value: 5.43e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1527 VVAAKDADFQCLNEKKEKLTEELQSLQRDIKAAEVNEDHHLQVLKESESLLQAKRAELETLKSQVTSQQQELAVLDSQLG 1606
Cdd:COG4942     14 AAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIA 93

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1607 HRREELLLLQDSLTQAKADLQEALTLGETEVAEKCSHIREVKSLLEELsfqkGELNVHISERRTQLTLIKQEIEKeeenl 1686
Cdd:COG4942     94 ELRAELEAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYL----KYLAPARREQAEELRADLAELAA----- 164

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1687 evVLQQLSKHKTELKNVADILQLETNELQSLKLQHDQKVVELEKtqvdllegklELESLQQTAQQQRRELERQRQLLERD 1766
Cdd:COG4942    165 --LRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEK----------ELAELAAELAELQQEAEELEALIARL 232

                          250
                   ....*....|...
gi 1958764989 1767 RRETERVRAETQA 1779
Cdd:COG4942    233 EAEAAAAAERTPA 245
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 645-1044 6.10e-06

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 51.61  E-value: 6.10e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  645 EKETLLQRLTEVKQEKDELEIVAMDAENMRKELAELENALQEQHEVNASLQQAQGDLSAYETE-LETQLKLKDAETSQLK 723
Cdd:TIGR02169  171 KKEKALEELEEVEENIERLDLIIDEKRQQLERLRREREKAERYQALLKEKREYEGYELLKEKEaLERQKEAIERQLASLE 250

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  724 QELENLVRRTQleqsvlqtELEKErqslrdalgkaqsSEEKQQENSELRAQLKQLQDDNSL-LKKQLKDFQSHLNHVVDG 802
Cdd:TIGR02169  251 EELEKLTEEIS--------ELEKR-------------LEEIEQLLEELNKKIKDLGEEEQLrVKEKIGELEAEIASLERS 309

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  803 LihpEEVAARVDELRKRLKlgagemrihspsdvlgKSLADLQKQFSEIlARSQWEKEEAQVRERKLHEEMALQQEKLANG 882
Cdd:TIGR02169  310 I---AEKERELEDAEERLA----------------KLEAEIDKLLAEI-EELEREIEEERKRRDKLTEEYAELKEELEDL 369

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  883 QEEFKQACERALEARIKFDKRQHnaRIQQLENEIHYLQENLKSMEKIQGLTDLQLQEADEEKERILAQLQELEKKKRRED 962
Cdd:TIGR02169  370 RAELEEVDKEFAETRDELKDYRE--KLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKA 447

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  963 ARSQEQflglDTELKSLKKAVAAsdklaaaeltiAKEQLKSLHGTVMRINQER---AEELQEAERSSREAMQAAKDLSRA 1039
Cdd:TIGR02169  448 LEIKKQ----EWKLEQLAADLSK-----------YEQELYDLKEEYDRVEKELsklQRELAEAEAQARASEERVRGGRAV 512


                   ....*
gi 1958764989 1040 EAEIE 1044
Cdd:TIGR02169  513 EEVLK 517
Drf_FH1 pfam06346
Formin Homology Region 1; This region is found in some of the Diaphanous related formins (Drfs) ...
 1238-1306 6.23e-06

Formin Homology Region 1; This region is found in some of the Diaphanous related formins (Drfs). It consists of low complexity repeats of around 12 residues.


Pssm-ID: 461881 [Multi-domain]  Cd Length: 157  Bit Score: 48.33  E-value: 6.23e-06
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1958764989 1238 PPfvPPPGYIMYTVLPDGSPVPQGVALYAPSPPLPHSSH----PLTPGTVVYGPPPAGaPIIYGPPPANFAVP 1306
Cdd:pfam06346   82 PP--PPPLPGGAGIPPPPPPLPGGAGVPPPPPPLPGGPGipppPPFPGGPGIPPPPPG-MGMPPPPPFGFGVP 151
Cast pfam10174
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ...
 1387-1995 6.34e-06

RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.


Pssm-ID: 431111 [Multi-domain]  Cd Length: 766  Bit Score: 51.36  E-value: 6.34e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1387 ERHQQRRDFIDGNVENLMTELEIEKSLKHHEDIVDEIECLEKTLlkRRSELR-EADR--LLAEAES-----ELACTKEKT 1458
Cdd:pfam10174   96 DFTTSPVDGEDKFSTPELTEENFRRLQSEHERQAKELFLLRKTL--EEMELRiETQKqtLGARDESikkllEMLQSKGLP 173

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1459 KSAVEKFTDAKRNLLQTESDAEALEKRAQETALNLVKAEQQLRLLQADAEDLEQHKIKQeeilkeinKVVAAKDADFQCL 1538
Cdd:pfam10174  174 KKSGEEDWERTRRIAEAEMQLGHLEVLLDQKEKENIHLREELHRRNQLQPDPAKTKALQ--------TVIEMKDTKISSL 245

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1539 NEKKEKLTEELQSL-----------QRDIKAAEVNEDHH----------LQVLKESESLLQAKRAELETLKSQVTSQQQE 1597
Cdd:pfam10174  246 ERNIRDLEDEVQMLktngllhtedrEEEIKQMEVYKSHSkfmknkidqlKQELSKKESELLALQTKLETLTNQNSDCKQH 325

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1598 LAVLDSQLGHRREELLLLQDSLTQAKADLQEaltlgetevaeKCSHIREVKSLLEELSFQKGELNVHISERRTQLTLIKQ 1677
Cdd:pfam10174  326 IEVLKESLTAKEQRAAILQTEVDALRLRLEE-----------KESFLNKKTKQLQDLTEEKSTLAGEIRDLKDMLDVKER 394

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1678 EIEKEEENLEVVLQQLSKHKTELKNVADILQletnELQSLKLQHDQKVVELEktqvdllEGKLELESLQQTAQQQRRELE 1757
Cdd:pfam10174  395 KINVLQKKIENLQEQLRDKDKQLAGLKERVK----SLQTDSSNTDTALTTLE-------EALSEKERIIERLKEQRERED 463

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1758 RQRqllerdRRETERVRAETQALQSCIECLNKE-----------KEHLQEQCESWEKKSSHAKRVLAATEESNNTEQSKL 1826
Cdd:pfam10174  464 RER------LEELESLKKENKDLKEKVSALQPEltekesslidlKEHASSLASSGLKKDSKLKSLEIAVEQKKEECSKLE 537

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1827 GQLevsvrKLQQELELLSQDKLALHSDSAQEQQQLQDKREALNSLQKELENTQDHLNLAKQDLMHTTKCQSALLSEQAQL 1906
Cdd:pfam10174  538 NQL-----KKAHNAEEAVRTNPEINDRIRLLEQEVARYKEESGKAQAEVERLLGILREVENEKNDKDKKIAELESLTLRQ 612

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1907 QKDVSQWTARLEScqKETETKEQQLQELQDEIRE--------SKLQLDQQEMVFQKLQKERESEEQKLVASIVSLEQQQG 1978
Cdd:pfam10174  613 MKEQNKKVANIKH--GQQEMKKKGAQLLEEARRRednladnsQQLQLEELMGALEKTRQELDATKARLSSTQQSLAEKDG 690

                          650
                   ....*....|....*..
gi 1958764989 1979 QLERELMDQKSKLEWLL 1995
Cdd:pfam10174  691 HLTNLRAERRKQLEEIL 707
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
436-698 6.34e-06

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 51.56  E-value: 6.34e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  436 DVQLEDTGKQIVAAQTRLSELHHEIEAAEQKVlratQEFKQLEEAIRqkkiSEAEKDLLLKQLSGRLRHLNKLRQEALDL 515
Cdd:COG3206    167 ELRREEARKALEFLEEQLPELRKELEEAEAAL----EEFRQKNGLVD----LSEEAKLLLQQLSELESQLAEARAELAEA 238

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  516 EAQLEKQRKEIAekheeiNSAQLATDLLDSkdpkqshmkaqkrgkeQQLDIMNKQYTQLESRLDEILCRIATETEEIKDL 595
Cdd:COG3206    239 EARLAALRAQLG------SGPDALPELLQS----------------PVIQQLRAQLAELEAELAELSARYTPNHPDVIAL 296

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  596 EQQLtdgqiaanEALKKDLEgviSGLQEYLGTIKGQAAQAQNECRKLQDEKETLLQRLTEVKQEKDELEIVAMDAENMRK 675
Cdd:COG3206    297 RAQI--------AALRAQLQ---QEAQRILASLEAELEALQAREASLQAQLAQLEARLAELPELEAELRRLEREVEVARE 365

                          250       260
                   ....*....|....*....|...
gi 1958764989  676 ELAELENALQEqhevnASLQQAQ 698
Cdd:COG3206    366 LYESLLQRLEE-----ARLAEAL 383
PRK11281 PRK11281
mechanosensitive channel MscK;
479-790 6.51e-06

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 51.45  E-value: 6.51e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  479 EAIRQKKISEAEKDLLLKQLSGRLRHLNKL---RQEALDLEAQLEKQRKEIAEKHEEINSAQlatdlldskdpkqshmKA 555
Cdd:PRK11281    46 DALNKQKLLEAEDKLVQQDLEQTLALLDKIdrqKEETEQLKQQLAQAPAKLRQAQAELEALK----------------DD 109

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  556 QKRGKEQQLDIMNkqYTQLESRLDEILcriateteeikdleQQLTDGQIAANEAlkkdlEGVISGLQEylGTIKGQAAQA 635
Cdd:PRK11281   110 NDEETRETLSTLS--LRQLESRLAQTL--------------DQLQNAQNDLAEY-----NSQLVSLQT--QPERAQAALY 166

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  636 QNECRKLQdeketLLQRLTEVKQEKDELEIVAMDAENMRKELAELENALQEQH-EVNASLQ---QAQGDL-SAYETELET 710
Cdd:PRK11281   167 ANSQRLQQ-----IRNLLKGGKVGGKALRPSQRVLLQAEQALLNAQNDLQRKSlEGNTQLQdllQKQRDYlTARIQRLEH 241

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  711 QLklkdaetsQLKQELENLVRRTQLEQSVlqteleKERQSLRDAlGKAQSSEEKQQEnSELRAQL-----KQLQDDNSLL 785
Cdd:PRK11281   242 QL--------QLLQEAINSKRLTLSEKTV------QEAQSQDEA-ARIQANPLVAQE-LEINLQLsqrllKATEKLNTLT 305


                   ....*
gi 1958764989  786 KKQLK 790
Cdd:PRK11281   306 QQNLR 310
LRR_4 pfam12799
Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a ...
 148-187 6.56e-06

Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a number of proteins with diverse functions and cellular locations. These repeats are usually involved in protein-protein interactions. Each Leucine Rich Repeat is composed of a beta-alpha unit. These units form elongated non-globular structures. Leucine Rich Repeats are often flanked by cysteine rich domains.


Pssm-ID: 463713 [Multi-domain]  Cd Length: 44  Bit Score: 44.93  E-value: 6.56e-06
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|.
gi 1958764989  148 RLRELNLSYNKISKIEGLENMCNLQKLNLAGN-EIEHIPGW 187
Cdd:pfam12799    2 NLEVLDLSNNQITDIPPLAKLPNLETLDLSGNnKITDLSDL 42
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1727-2073 6.97e-06

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 51.58  E-value: 6.97e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1727 ELEKTQVDLLEGKLELESLQQTAQQQRRELERQRQLLERDRRETERVRAETQALQSCIECLNKEKEHLQEQCESwekkss 1806
Cdd:PRK02224   259 EIEDLRETIAETEREREELAEEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRDRLEE------ 332

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1807 haKRVlAATEESNNTEQsklgqLEVSVRKLQQELELLSQDKLALHSDSAQEQQQLQDKREALNSLQKELENTQDHLNLAK 1886
Cdd:PRK02224   333 --CRV-AAQAHNEEAES-----LREDADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAP 404

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1887 QDLMHTTKCQSALLSEQAQLQKDVSQWTARLESCQKETEtKEQQLQElqdeirESKLQLDQQEMvfqklqkeresEEQKL 1966
Cdd:PRK02224   405 VDLGNAEDFLEELREERDELREREAELEATLRTARERVE-EAEALLE------AGKCPECGQPV-----------EGSPH 466

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1967 VASIVSLEQQQGQLERELMDQKSKLEwlltDVSAAEGRLRTLQKEERCTESLEKMLSQAKQQLSEREQQLMEKSGDLLAL 2046
Cdd:PRK02224   467 VETIEEDRERVEELEAELEDLEEEVE----EVEERLERAEDLVEAEDRIERLEERREDLEELIAERRETIEEKRERAEEL 542

                          330       340
                   ....*....|....*....|....*..
gi 1958764989 2047 QKEADGMRADFSLLRNQFLTERKKAEK 2073
Cdd:PRK02224   543 RERAAELEAEAEEKREAAAEAEEEAEE 569
CALCOCO1 pfam07888
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ...
 1732-2056 7.02e-06

Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.


Pssm-ID: 462303 [Multi-domain]  Cd Length: 488  Bit Score: 51.05  E-value: 7.02e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1732 QVDLLEGKLELESLQQTAQQQRRELERQRQLLERDRRETERVRAEtqaLQSCIECLNKEKEHLQEQCESWEKKSSHAKRV 1811
Cdd:pfam07888   33 QNRLEECLQERAELLQAQEAANRQREKEKERYKRDREQWERQRRE---LESRVAELKEELRQSREKHEELEEKYKELSAS 109

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1812 LAATEESNNTEQSKLGQLEVSVRKLQQELELLSQDKLALHSD-------SAQEQQQLQDKREALNSLQKELENTQDHLNL 1884
Cdd:pfam07888  110 SEELSEEKDALLAQRAAHEARIRELEEDIKTLTQRVLERETElermkerAKKAGAQRKEEEAERKQLQAKLQQTEEELRS 189

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1885 AKQDLMHTTKCQSALLSEQAQLQKDVSQWTARLESCQKETETKEQQLQELQ--------DEIRESKLQLDQQEMVFQKLQ 1956
Cdd:pfam07888  190 LSKEFQELRNSLAQRDTQVLQLQDTITTLTQKLTTAHRKEAENEALLEELRslqerlnaSERKVEGLGEELSSMAAQRDR 269

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1957 KERESEEQKLVASIVSLEQQQGQL-----------ERELMDQ-----KSKLEWLLTDVSAAEGRlrtLQKEERCTESLEK 2020
Cdd:pfam07888  270 TQAELHQARLQAAQLTLQLADASLalregrarwaqERETLQQsaeadKDRIEKLSAELQRLEER---LQEERMEREKLEV 346

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|
gi 1958764989 2021 MLSQAKQ----QLSEREQQLMEKSGDLLALQKEADGMRAD 2056
Cdd:pfam07888  347 ELGREKDcnrvQLSESRRELQELKASLRVAQKEKEQLQAE 386
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 444-1067 7.14e-06

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 51.49  E-value: 7.14e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  444 KQIVAAQTRLSELHHEIEAAEQKVLRATQefkQLEEAIRQKKISEAEKDLLLKQLSGRLRHLNKLRQEALdlEAQLEKQR 523
Cdd:COG3096    347 EKIERYQEDLEELTERLEEQEEVVEEAAE---QLAEAEARLEAAEEEVDSLKSQLADYQQALDVQQTRAI--QYQQAVQA 421

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  524 KEIAEKHEEIN--SAQLATDLLDSKDPKQSHMKAQKRGKEQQLDIMNKQYTQLESRLdEILCRIATETEEikdleqqlTD 601
Cdd:COG3096    422 LEKARALCGLPdlTPENAEDYLAAFRAKEQQATEEVLELEQKLSVADAARRQFEKAY-ELVCKIAGEVER--------SQ 492

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  602 GQIAANEALK-----KDLEGVISGLQEYLGTIKgQAAQAQNECRKLQDEketLLQRLTEVKQEKDELEIVAMDAEnmrKE 676
Cdd:COG3096    493 AWQTARELLRryrsqQALAQRLQQLRAQLAELE-QRLRQQQNAERLLEE---FCQRIGQQLDAAEELEELLAELE---AQ 565

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  677 LAELENALQEQHEVNASLQQAQGDLSAYETELETQ----LKLKDAET---SQLKQELENLVRRTQLEQSVLqtELEKERQ 749
Cdd:COG3096    566 LEELEEQAAEAVEQRSELRQQLEQLRARIKELAARapawLAAQDALErlrEQSGEALADSQEVTAAMQQLL--EREREAT 643

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  750 SLRDALGKAQSSEEKQ-----QENSELRAQLKQLQD------------------------------------DNSLLKKQ 788
Cdd:COG3096    644 VERDELAARKQALESQierlsQPGGAEDPRLLALAErlggvllseiyddvtledapyfsalygparhaivvpDLSAVKEQ 723

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  789 LKDFQSHLNHVV----------DGLIHPEEVAARV------------------------------------DELRKRL-K 821
Cdd:COG3096    724 LAGLEDCPEDLYliegdpdsfdDSVFDAEELEDAVvvklsdrqwrysrfpevplfgraarekrleelraerDELAEQYaK 803

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  822 LGAGEMRI----HSPSDVLGKSLA------------DLQKQFSEILAR-SQWEKEEAQVRE-------------RKLHEE 871
Cdd:COG3096    804 ASFDVQKLqrlhQAFSQFVGGHLAvafapdpeaelaALRQRRSELERElAQHRAQEQQLRQqldqlkeqlqllnKLLPQA 883

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  872 MALQQEKLANGQEEFKQACERALEARIKFdkRQHNARIQQLENEIHYLQENLKSMEKIQgltdLQLQEADEEKERILAQL 951
Cdd:COG3096    884 NLLADETLADRLEELREELDAAQEAQAFI--QQHGKALAQLEPLVAVLQSDPEQFEQLQ----ADYLQAKEQQRRLKQQI 957

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  952 QELEKKKRREDARSQEQFLGLDTELKSLKKAVAASDKLAAAELTIAKEQLKSLHGTVMRINQERA----------EELQE 1021
Cdd:COG3096    958 FALSEVVQRRPHFSYEDAVGLLGENSDLNEKLRARLEQAEEARREAREQLRQAQAQYSQYNQVLAslkssrdakqQTLQE 1037

                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1958764989 1022 AER--------SSREAMQAA----------------------KDLSRAEAEIELLQHLLRERE---GQFRDEMENAHVG 1067
Cdd:COG3096   1038 LEQeleelgvqADAEAEERArirrdelheelsqnrsrrsqleKQLTRCEAEMDSLQKRLRKAErdyKQEREQVVQAKAG 1116
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 754-992 8.17e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 50.53  E-value: 8.17e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  754 ALGKAQSSEEKQQENSELRAQLKQLQDDNSLLKKQLKDFQSHLnhvvdglihpEEVAARVDELRKRLKLGAGEMRihsps 833
Cdd:COG4942     15 AAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQL----------AALERRIAALARRIRALEQELA----- 79

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  834 dVLGKSLADLQKQFSEILARSQWEKEEAQVRERKLHEEMALQQEKLANGQEEFKQACERA--LEARIKFDK------RQH 905
Cdd:COG4942     80 -ALEAELAELEKEIAELRAELEAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLqyLKYLAPARReqaeelRAD 158

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  906 NARIQQLENEIHYLQENLKSMEKIQGLTDLQLQEADEEKERILAQLQELEKKKRREDARSQEQFLGLDTELKSLKKAVAA 985
Cdd:COG4942    159 LAELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAA 238


                   ....*..
gi 1958764989  986 SDKLAAA 992
Cdd:COG4942    239 AAERTPA 245
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1811-2035 1.02e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 50.15  E-value: 1.02e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1811 VLAATEESNNTEQSKLGQLEVSVRKLQQELELLSQDKLALHSD-------SAQEQQQLQDKREALNSLQKELENTQDHLN 1883
Cdd:COG4942     14 AAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQlaalerrIAALARRIRALEQELAALEAELAELEKEIA 93

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1884 LAKQDLmhttKCQSALLSEQ---AQLQKDVSQWTARLESCQ-KETETKEQQLQELQDEIRESKLQLDQQEMVFQKLQKER 1959
Cdd:COG4942     94 ELRAEL----EAQKEELAELlraLYRLGRQPPLALLLSPEDfLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAEL 169

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1958764989 1960 ESEEQKLVASIVSLEQQQGQLERELMDQKSKLEWLLTDVSAAEGRLRTLQKEErctESLEKMLSQAKQQLSEREQQ 2035
Cdd:COG4942    170 EAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEA---EELEALIARLEAEAAAAAER 242
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
607-817 1.08e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 51.07  E-value: 1.08e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  607 NEALKKDLEGVISGLQEYLGTIKGQAAQAQNECRKLQDEKEtLLQRLTEVKQEKDELEIVAMDAENMRKELAELEN---- 682
Cdd:COG4913    608 NRAKLAALEAELAELEEELAEAEERLEALEAELDALQERRE-ALQRLAEYSWDEIDVASAEREIAELEAELERLDAssdd 686

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  683 --ALQEQHE-VNASLQQAQGDLSAYETEL-ETQLKLKDAETsQLKQELENLVRRTQLEQSVLQTELEKERQSLRDALGKA 758
Cdd:COG4913    687 laALEEQLEeLEAELEELEEELDELKGEIgRLEKELEQAEE-ELDELQDRLEAAEDLARLELRALLEERFAAALGDAVER 765

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  759 QSSEEKQQENSELRAQLKQLQDD-NSLLKKQLKDFQSHLNHVVDGLIHPEEVAARVDELR 817
Cdd:COG4913    766 ELRENLEERIDALRARLNRAEEElERAMRAFNREWPAETADLDADLESLPEYLALLDRLE 825
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 438-789 1.29e-05

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 50.72  E-value: 1.29e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  438 QLEDTGKQIVAAQTRLSELHHEIE-------AAEQKVLRATQEFKQLEEAIR-QKKISEAEKDLllKQLSGRLRHLNKLR 509
Cdd:COG3096    293 ELFGARRQLAEEQYRLVEMARELEelsaresDLEQDYQAASDHLNLVQTALRqQEKIERYQEDL--EELTERLEEQEEVV 370

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  510 QEALDLEAQLEKQRKEIAEKHEEINSaQLAtDLLDSKDPKQSHM-----------KAQKRGKEQQLDIMN--KQYTQLES 576
Cdd:COG3096    371 EEAAEQLAEAEARLEAAEEEVDSLKS-QLA-DYQQALDVQQTRAiqyqqavqaleKARALCGLPDLTPENaeDYLAAFRA 448

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  577 RLDEIlcriateTEEIKDLEQQLTDGQIAANEaLKKDLEGVISGLQEylgTIKGQAAQAQNECRKLQDEKETLLQRLTEV 656
Cdd:COG3096    449 KEQQA-------TEEVLELEQKLSVADAARRQ-FEKAYELVCKIAGE---VERSQAWQTARELLRRYRSQQALAQRLQQL 517

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  657 KQEKDELEIVAMDAENMRKELAELENALQEQHEVNASLQQAQGDLSAYETELETQLKLKDAETSQLKQELENL-VRRTQL 735
Cdd:COG3096    518 RAQLAELEQRLRQQQNAERLLEEFCQRIGQQLDAAEELEELLAELEAQLEELEEQAAEAVEQRSELRQQLEQLrARIKEL 597

                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1958764989  736 EQS-----VLQTELEKERQSLRDALGKAQSSEEKQQENSELRAQLKQLQDDNSLLKKQL 789
Cdd:COG3096    598 AARapawlAAQDALERLREQSGEALADSQEVTAAMQQLLEREREATVERDELAARKQAL 656
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 438-599 1.35e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 49.76  E-value: 1.35e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  438 QLEDTGKQIVAAQTRLSELHHEIEAAEQKVLRATQEFKQLEEAIRQKK------------ISEAEKDLLL------KQLS 499
Cdd:COG4942     56 QLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKeelaellralyrLGRQPPLALLlspedfLDAV 135

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  500 GRLRHLNKLRQEALDLEAQLEKQRKEIAEKHEEINSAQLATD-LLDSKDPKQSHMKAQKRGKEQQLDIMNKQYTQLESRL 578
Cdd:COG4942    136 RRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEaLLAELEEERAALEALKAERQKLLARLEKELAELAAEL 215

                          170       180
                   ....*....|....*....|.
gi 1958764989  579 DEILCRIATETEEIKDLEQQL 599
Cdd:COG4942    216 AELQQEAEELEALIARLEAEA 236
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1838-2013 1.40e-05

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 50.15  E-value: 1.40e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1838 QELELLSQDKLALhsdsAQEQQQLQDKREALNSLQKELENTQDHLNLAKQDLMHTTKCQSA--LLSEQAQLQKDVSQWTA 1915
Cdd:COG4717     71 KELKELEEELKEA----EEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLlpLYQELEALEAELAELPE 146

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1916 RLESCQ---KETETKEQQLQELQDEIRESKLQLDQQEmvfQKLQKERESEEQKLVASIVSLEQQQGQLERELMDQKSKLE 1992
Cdd:COG4717    147 RLEELEerlEELRELEEELEELEAELAELQEELEELL---EQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELE 223

                          170       180
                   ....*....|....*....|.
gi 1958764989 1993 WLLTDVSAAEGRLRTLQKEER 2013
Cdd:COG4717    224 ELEEELEQLENELEAAALEER 244
LRR_4 pfam12799
Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a ...
 126-167 1.40e-05

Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a number of proteins with diverse functions and cellular locations. These repeats are usually involved in protein-protein interactions. Each Leucine Rich Repeat is composed of a beta-alpha unit. These units form elongated non-globular structures. Leucine Rich Repeats are often flanked by cysteine rich domains.


Pssm-ID: 463713 [Multi-domain]  Cd Length: 44  Bit Score: 43.77  E-value: 1.40e-05
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|...
gi 1958764989  126 KLEVLNLSYNLIAKIEKVDKLLRLRELNLSYN-KISKIEGLEN 167
Cdd:pfam12799    2 NLEVLDLSNNQITDIPPLAKLPNLETLDLSGNnKITDLSDLAN 44
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 450-1005 1.44e-05

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 50.61  E-value: 1.44e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  450 QTRLSELHHEIEAAEQKVLRATQEFKQLEEAIRQKKISEAE--KDLLLKQLSGRLRHL----NKLRQEALDLEAQLEKQR 523
Cdd:pfam12128  353 QSELENLEERLKALTGKHQDVTAKYNRRRSKIKEQNNRDIAgiKDKLAKIREARDRQLavaeDDLQALESELREQLEAGK 432

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  524 KEIAEKHEE-----------INSAQLATDLLDSKDPKQSHMKAQKRGKEQQldimNKQYTQLESRLDEILCRIATETEEI 592
Cdd:pfam12128  433 LEFNEEEYRlksrlgelklrLNQATATPELLLQLENFDERIERAREEQEAA----NAEVERLQSELRQARKRRDQASEAL 508

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  593 KDLEQQLTDGQiAANEALKKDLEGVISGLQEYLGTikgQAAQAQNECRKLQDEK---ETLLQRLTEVKQEKDE------- 662
Cdd:pfam12128  509 RQASRRLEERQ-SALDELELQLFPQAGTLLHFLRK---EAPDWEQSIGKVISPEllhRTDLDPEVWDGSVGGElnlygvk 584

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  663 LEIVAMDA-------ENMRKELAELENALQEQHEVNASLQQAQGDLSAYETELetQLKLKDAETSqLKQELENLVRrtql 735
Cdd:pfam12128  585 LDLKRIDVpewaaseEELRERLDKAEEALQSAREKQAAAEEQLVQANGELEKA--SREETFARTA-LKNARLDLRR---- 657

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  736 eqsvlqteLEKERQSLRDALGKAQSSEEKQQENS--ELRAQLKQLQDDNSLLKKQLKD--------FQSHLNHVVDGL-- 803
Cdd:pfam12128  658 --------LFDEKQSEKDKKNKALAERKDSANERlnSLEAQLKQLDKKHQAWLEEQKEqkrearteKQAYWQVVEGALda 729

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  804 ---IHPEEVAARVDELRKRLKLGAGEM-RIHSPSDVLGKSLADLQKQFSEILAR-SQWEKEEAQVRE--RKLHEEMALQQ 876
Cdd:pfam12128  730 qlaLLKAAIAARRSGAKAELKALETWYkRDLASLGVDPDVIAKLKREIRTLERKiERIAVRRQEVLRyfDWYQETWLQRR 809

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  877 EKLANGQEEFKQACER------ALEARIKFDKRQHNARIQQLENEIHYLQENLKSME-KIQGLTDLQL----QEADEEKE 945
Cdd:pfam12128  810 PRLATQLSNIERAISElqqqlaRLIADTKLRRAKLEMERKASEKQQVRLSENLRGLRcEMSKLATLKEdansEQAQGSIG 889

                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1958764989  946 RILAQLQELEKKKRREDARSQEQFLGLDTELKSLKKAVAAS--DKLAAAELTIAKEQLKSLH 1005
Cdd:pfam12128  890 ERLAQLEDLKLKRDYLSESVKKYVEHFKNVIADHSGSGLAEtwESLREEDHYQNDKGIRLLD 951
RNA1 COG5238
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ...
 49-238 1.47e-05

Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];


Pssm-ID: 444072 [Multi-domain]  Cd Length: 434  Bit Score: 49.79  E-value: 1.47e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989   49 GGQCPAQAELTDENTMPLESQQHKGADPYVGVRYI----TEALIKKLTKQDNLALVKSLNLSLSKDGGKKFryIENLEKC 124
Cdd:COG5238    158 LLGLAARLGLLAAISMAKALQNNSVETVYLGCNQIgdegIEELAEALTQNTTVTTLWLKRNPIGDEGAEIL--AEALKGN 235

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  125 VKLEVLNLSYN------LIAKIEKVDKLLRLRELNLSYNKISK------IEGLENMCNLQKLNLAGNEIEHiPGWFS--- 189
Cdd:COG5238    236 KSLTTLDLSNNqigdegVIALAEALKNNTTVETLYLSGNQIGAegaialAKALQGNTTLTSLDLSVNRIGD-EGAIAlae 314

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1958764989  190 --KKLKSLRVLNLKGNKISSLQDVSKLKPLQD---LTSLTLIDNP-----VVALPHYLQ 238
Cdd:COG5238    315 glQGNKTLHTLNLAYNGIGAQGAIALAKALQEnttLHSLDLSDNQigdegAIALAKYLE 373
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1929-2099 1.92e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 49.91  E-value: 1.92e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1929 QQLQELQDEIRESKLQLDQQEMVFQKLQKERESEEQKLVAS-IVSLEQQQGQLERELMDQKSKLEWLLTDVSAAEGRLRT 2007
Cdd:COG4913    255 EPIRELAERYAAARERLAELEYLRAALRLWFAQRRLELLEAeLEELRAELARLEAELERLEARLDALREELDELEAQIRG 334

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 2008 LQKEERctESLEKMLSQAKQQLSEREQQLMEKSGDLLALQKEADGMRADFSLLRNQFLTERKKAEKQVAGLKEA---LKI 2084
Cdd:COG4913    335 NGGDRL--EQLEREIERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAEAAALLEALEEELEALEEAlaeAEA 412

                          170
                   ....*....|....*
gi 1958764989 2085 QRSQLEKNLLEQKQE 2099
Cdd:COG4913    413 ALRDLRRELRELEAE 427
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1416-1883 2.62e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 49.53  E-value: 2.62e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1416 HEDIVDEIECLEkTLlkrrSELREADRLLAEAESELAcTKEKTKSAVEKFTDAKRnllqtesdAEALEKRAQETALNLVK 1495
Cdd:COG4913    241 HEALEDAREQIE-LL----EPIRELAERYAAARERLA-ELEYLRAALRLWFAQRR--------LELLEAELEELRAELAR 306

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1496 AEQQLRLLQADAEDLEQHKIK-QEEILKEINKVVAAKDADFQCLNEKKEKLTEELQSLQRDIKAAEVNEDHHLQVLKESE 1574
Cdd:COG4913    307 LEAELERLEARLDALREELDElEAQIRGNGGDRLEQLEREIERLERELEERERRRARLEALLAALGLPLPASAEEFAALR 386

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1575 SLLQAKRAELETLKSQVTSQQQELAVLDSQLGHRREELLLLQDSL-----------TQAKADLQEALTLGET-------- 1635
Cdd:COG4913    387 AEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLerrksniparlLALRDALAEALGLDEAelpfvgel 466

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1636 -EVAEKCS----------------------HIREVKSLLEELsfqKGELNVHISERRTQLTLIKQEIEKEEENLEVVLQQ 1692
Cdd:COG4913    467 iEVRPEEErwrgaiervlggfaltllvppeHYAAALRWVNRL---HLRGRLVYERVRTGLPDPERPRLDPDSLAGKLDFK 543

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1693 LSKH----KTELKNVADILQLETneLQSLK------------------LQHD----------------QKVVELEKtQVD 1734
Cdd:COG4913    544 PHPFrawlEAELGRRFDYVCVDS--PEELRrhpraitragqvkgngtrHEKDdrrrirsryvlgfdnrAKLAALEA-ELA 620

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1735 LLEGKL-ELESLQQTAQQQRRELERQRQLLER------DRRETERVRAETQALQSCIECL---NKEKEHLQEQCESWEKK 1804
Cdd:COG4913    621 ELEEELaEAEERLEALEAELDALQERREALQRlaeyswDEIDVASAEREIAELEAELERLdasSDDLAALEEQLEELEAE 700

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1958764989 1805 SSHAKRVLAATEESNNTEQSKLGQLEVSVRKLQQELELLSQDKLALHSDSAQEQQQLQDKREALNSLQKELENTQDHLN 1883
Cdd:COG4913    701 LEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLEERFAAALGDAVERELRENLEERIDALR 779
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 1723-2142 2.63e-05

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 49.33  E-value: 2.63e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1723 QKVVELEKTQVDLLEGKLELESLQQTAQQQRreLERQRQLLERDRRETERVRAETQALQSCIECLNKEKEHLQEQCESWE 1802
Cdd:pfam05483  225 QHLEEEYKKEINDKEKQVSLLLIQITEKENK--MKDLTFLLEESRDKANQLEEKTKLQDENLKELIEKKDHLTKELEDIK 302

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1803 KKSSHAKRVLAATEESNNTEQSKLGQLevsVRKLQQELELLSQDKLALHSDSAQEQQQLQDKREALNSLQKELENTQDHL 1882
Cdd:pfam05483  303 MSLQRSMSTQKALEEDLQIATKTICQL---TEEKEAQMEELNKAKAAHSFVVTEFEATTCSLEELLRTEQQRLEKNEDQL 379

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1883 NLAKQdlmhttkcqsallseqaQLQKDVSQwtarLESCQKETETKEQQLQELQDEIRESKLQLDQQEMvFQKLQKERESE 1962
Cdd:pfam05483  380 KIITM-----------------ELQKKSSE----LEEMTKFKNNKEVELEELKKILAEDEKLLDEKKQ-FEKIAEELKGK 437

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1963 EQKLVASIVSLEQQQGQLERELMDQKSKLEWLLTDVSAAEGRLRTLQ-KEERCTESLEKMLSQAK---QQLSEREQQLME 2038
Cdd:pfam05483  438 EQELIFLLQAREKEIHDLEIQLTAIKTSEEHYLKEVEDLKTELEKEKlKNIELTAHCDKLLLENKeltQEASDMTLELKK 517

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 2039 KSGDLLALQKEADGMRADFSLLRNQFLTERKKAE---KQVAGLKEALKIQRSQLEKNLLEQKQENSCMQKEMATIELVAQ 2115
Cdd:pfam05483  518 HQEDIINCKKQEERMLKQIENLEEKEMNLRDELEsvrEEFIQKGDEVKCKLDKSEENARSIEYEVLKKEKQMKILENKCN 597

                          410       420
                   ....*....|....*....|....*..
gi 1958764989 2116 DNHERARRLMKELRQMQQEYLELKKQS 2142
Cdd:pfam05483  598 NLKKQIENKNKNIEELHQENKALKKKG 624
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1508-2083 3.28e-05

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 49.29  E-value: 3.28e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1508 EDLEQHKIKQEEILKEINKvvaakdadfqcLNEKKEKLTEELQSLQRDIKAAEVNEDHHLQVLKESESLLQAKRAELETL 1587
Cdd:PRK03918   158 DDYENAYKNLGEVIKEIKR-----------RIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEKL 226

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1588 KSQVtsqqQELAVLDSQLGHRREELLLLQDSLTQAKADLQEAltlgETEVAEKCSHIREVKSLLEELSFQKGELNVHISE 1667
Cdd:PRK03918   227 EKEV----KELEELKEEIEELEKELESLEGSKRKLEEKIREL----EERIEELKKEIEELEEKVKELKELKEKAEEYIKL 298

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1668 RRtqltlikqeiekEEENLEVVLQQLSKHKTELKNVADILQLETNELQSLKlqhdQKVVELEKTQVDLLEGKLELESLQQ 1747
Cdd:PRK03918   299 SE------------FYEEYLDELREIEKRLSRLEEEINGIEERIKELEEKE----ERLEELKKKLKELEKRLEELEERHE 362

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1748 TAQQQRRELERQRQLLERDR-RETERVRAETQALQSCIECLNKEKEHLQEQCESWEKKSSHAKRVLAATEESNN------ 1820
Cdd:PRK03918   363 LYEEAKAKKEELERLKKRLTgLTPEKLEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKAKGkcpvcg 442

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1821 ---TEQSKLGQLE---VSVRKLQQELELLSQDKLALHSDSAQEQQQLQDKRE--ALNSLQKELENTQDHLN-LAKQDLMH 1891
Cdd:PRK03918   443 relTEEHRKELLEeytAELKRIEKELKEIEEKERKLRKELRELEKVLKKESEliKLKELAEQLKELEEKLKkYNLEELEK 522

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1892 TTKCQSALLSEQAQLQKDVSQWTARLESCQ---KETETKEQQLQELQDEIRESKLQLDQQEMVFQKLQKERESEEQKLVA 1968
Cdd:PRK03918   523 KAEEYEKLKEKLIKLKGEIKSLKKELEKLEelkKKLAELEKKLDELEEELAELLKELEELGFESVEELEERLKELEPFYN 602

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1969 SIVSLEQQQGQLERELmdqkSKLEWLLTDVSAAEgrlRTLQKEERCTESLEKMLSQAKQQLSEREQQlmEKSGDLLALQK 2048
Cdd:PRK03918   603 EYLELKDAEKELEREE----KELKKLEEELDKAF---EELAETEKRLEELRKELEELEKKYSEEEYE--ELREEYLELSR 673

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|....*...
gi 1958764989 2049 EADGMRADFSLLRNQF-------------LTERKKAEKQVAGLKEALK 2083
Cdd:PRK03918   674 ELAGLRAELEELEKRReeikktleklkeeLEEREKAKKELEKLEKALE 721
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
590-794 3.53e-05

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 48.86  E-value: 3.53e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  590 EEIKDLEQQLTDGQIAANEALKKD-LEGVISGLQEYLGTIKGQAAQAQNECRK---------LQDEKETLLQRLTEVKQE 659
Cdd:COG3206    148 ELAAAVANALAEAYLEQNLELRREeARKALEFLEEQLPELRKELEEAEAALEEfrqknglvdLSEEAKLLLQQLSELESQ 227

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  660 KDELEIVAMDAEN----MRKELAELENALQE--QHEVNASLQQAQGDLSAYETELETQLKLKDAETSQLKQELENLVRRT 733
Cdd:COG3206    228 LAEARAELAEAEArlaaLRAQLGSGPDALPEllQSPVIQQLRAQLAELEAELAELSARYTPNHPDVIALRAQIAALRAQL 307

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1958764989  734 QLEQSVLQTELEKERQSLRDALGKAQSSEEKQQEN----SELRAQLKQLQDDNSLLKKQLKDFQS 794
Cdd:COG3206    308 QQEAQRILASLEAELEALQAREASLQAQLAQLEARlaelPELEAELRRLEREVEVARELYESLLQ 372
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 427-671 3.57e-05

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 48.29  E-value: 3.57e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  427 HAPRAQAPPDVQLEDTGKQIVAAQTRLSELHHEIEAAEQKVLRATQEFKQLEEAIrqkkiseaekdlllkqlsgrlrhlN 506
Cdd:COG3883     13 FADPQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEI------------------------D 68

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  507 KLRQEALDLEAQLEKQRKEIAEK----HEEINSAQLATDLLDSKDPKQ--SHMKAQKRGKEQQLDIMNkQYTQLESRLDE 580
Cdd:COG3883     69 KLQAEIAEAEAEIEERREELGERaralYRSGGSVSYLDVLLGSESFSDflDRLSALSKIADADADLLE-ELKADKAELEA 147

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  581 ILCRIATETEEIKDLEQQLtdgqiaanEALKKDLEGVISGLQEYLGTIKGQAAQAQNECRKLQDEKETLLQRLTEVKQEK 660
Cdd:COG3883    148 KKAELEAKLAELEALKAEL--------EAAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAA 219

                          250
                   ....*....|.
gi 1958764989  661 DELEIVAMDAE 671
Cdd:COG3883    220 AAAAAAAAAAA 230
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 1426-1586 3.88e-05

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 47.23  E-value: 3.88e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1426 LEKTLLKRRSELREADRLLAEAESELACTKEKTKSAVEKFTDAKRNLLQTESDAEALEKRAQ--ETALNLVKAEQQLRLL 1503
Cdd:COG1579     15 LDSELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKkyEEQLGNVRNNKEYEAL 94

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1504 QADAEDLEQHKIKQEEILKEINKVVAAKDADFQCLNEKKEKLTEELQSLQRDIKAAevnedhhLQVLKESESLLQAKRAE 1583
Cdd:COG1579     95 QKEIESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDEE-------LAELEAELEELEAEREE 167


                   ...
gi 1958764989 1584 LET 1586
Cdd:COG1579    168 LAA 170
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 244-913 4.99e-05

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 48.58  E-value: 4.99e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  244 LRSLES----LEGQPVTTQDRQEAFERFSLEEIE--------RLEKDLEKKTVETEELKNKQTKFLEEIKHQDKLNKSLK 311
Cdd:pfam15921  226 LRELDTeisyLKGRIFPVEDQLEALKSESQNKIElllqqhqdRIEQLISEHEVEITGLTEKASSARSQANSIQSQLEIIQ 305

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  312 EEAMLQKQSCEELESDLNTKKELLKQKTVELTRACQ-KQYELEQELAFYKidakfeplnyypSEYAEmdkspdespyigk 390
Cdd:pfam15921  306 EQARNQNSMYMRQLSDLESTVSQLRSELREAKRMYEdKIEELEKQLVLAN------------SELTE------------- 360

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  391 SRYKRNMFATETYIVSDaqavQVRKMVPDGGQLRHEHAPRAQAPPDVQLEDTGKQIVaaqtrLSELHHEIEAAEQKVlra 470
Cdd:pfam15921  361 ARTERDQFSQESGNLDD----QLQKLLADLHKREKELSLEKEQNKRLWDRDTGNSIT-----IDHLRRELDDRNMEV--- 428

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  471 tQEFKQLEEAIRQKKISEAEKDLLLKQlsGRLRHLNKLRQealdLEAQLEKQRKEIAEKHEEINSAQLAtdlLDSKDPKQ 550
Cdd:pfam15921  429 -QRLEALLKAMKSECQGQMERQMAAIQ--GKNESLEKVSS----LTAQLESTKEMLRKVVEELTAKKMT---LESSERTV 498

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  551 SHMKAQKRGKEQQLDIMNKQYTQLESRLDEILcriaTETEEIKDLEQQLTDGQiAANEALKKDLEG---VISGLQEYLGT 627
Cdd:pfam15921  499 SDLTASLQEKERAIEATNAEITKLRSRVDLKL----QELQHLKNEGDHLRNVQ-TECEALKLQMAEkdkVIEILRQQIEN 573

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  628 IKGQAAQAQNECRKLQDEKETLLQRLTEVKQEKDELEIVAMDAENMRKEL----AELEnaLQEQHEVNASLQQAQGdlsa 703
Cdd:pfam15921  574 MTQLVGQHGRTAGAMQVEKAQLEKEINDRRLELQEFKILKDKKDAKIRELearvSDLE--LEKVKLVNAGSERLRA---- 647

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  704 yeteletqlkLKDAEtsQLKQELENLVRRTQLEQSVLQTELEKERQSLRDalgkaqSSEEKQQENSELRAQLKQLQDDNS 783
Cdd:pfam15921  648 ----------VKDIK--QERDQLLNEVKTSRNELNSLSEDYEVLKRNFRN------KSEEMETTTNKLKMQLKSAQSELE 709

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  784 LLKKQLKDFQSHLNHVVD-GLIHPEEVAAR---VDELRKRLKLGAGEM-RIHSPSDVLGKSLADLQKQFSEILARSQWEK 858
Cdd:pfam15921  710 QTRNTLKSMEGSDGHAMKvAMGMQKQITAKrgqIDALQSKIQFLEEAMtNANKEKHFLKEEKNKLSQELSTVATEKNKMA 789

                          650       660       670       680       690       700
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1958764989  859 EEAQV---RERKLHEEMALQQEKLANGQEEFKQA---CERALEARIKFdKRQHNARIQQLE 913
Cdd:pfam15921  790 GELEVlrsQERRLKEKVANMEVALDKASLQFAECqdiIQRQEQESVRL-KLQHTLDVKELQ 849
mukB PRK04863
chromosome partition protein MukB;
502-895 5.34e-05

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 48.80  E-value: 5.34e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  502 LRHLNKLR---QEALDLEAQLEKQRKEIA---EKHEEI---------NSAQLATDLLDSKDPKQSHMKA---QKRGKEQQ 563
Cdd:PRK04863   275 MRHANERRvhlEEALELRRELYTSRRQLAaeqYRLVEMarelaelneAESDLEQDYQAASDHLNLVQTAlrqQEKIERYQ 354

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  564 LDImnkqyTQLESRLDEILCRIATETEEIKDLEQQLTdgqiaANEALKKDLEGVISGLQEYLGTIKGQAAQAQNECRKLQ 643
Cdd:PRK04863   355 ADL-----EELEERLEEQNEVVEEADEQQEENEARAE-----AAEEEVDELKSQLADYQQALDVQQTRAIQYQQAVQALE 424

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  644 DEKETLLQRLTEVKQEKDELEIVAMDAENMRKELAELENALQ------EQHEVNASL-QQAQGDLSAYE-----TELETQ 711
Cdd:PRK04863   425 RAKQLCGLPDLTADNAEDWLEEFQAKEQEATEELLSLEQKLSvaqaahSQFEQAYQLvRKIAGEVSRSEawdvaRELLRR 504

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  712 L---KLKDAETSQLKQELENLVRRTQLEQSVlqtelekeRQSLRDALGKAQSSEEKQQENSELRAQLKQLQDDNSLLKKQ 788
Cdd:PRK04863   505 LreqRHLAEQLQQLRMRLSELEQRLRQQQRA--------ERLLAEFCKRLGKNLDDEDELEQLQEELEARLESLSESVSE 576

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  789 LKDFQSHLNHvvdgliHPEEVAARVDELRKRlklgAGEMRIHSPsdvlgkSLADLQKQFSEILARSQwekEEAQVRERKL 868
Cdd:PRK04863   577 ARERRMALRQ------QLEQLQARIQRLAAR----APAWLAAQD------ALARLREQSGEEFEDSQ---DVTEYMQQLL 637

                          410       420
                   ....*....|....*....|....*..
gi 1958764989  869 HEEMALQQEKlaNGQEEFKQACERALE 895
Cdd:PRK04863   638 ERERELTVER--DELAARKQALDEEIE 662
PRK10929 PRK10929
putative mechanosensitive channel protein; Provisional
 506-916 5.80e-05

putative mechanosensitive channel protein; Provisional


Pssm-ID: 236798 [Multi-domain]  Cd Length: 1109  Bit Score: 48.51  E-value: 5.80e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  506 NKLRQEALDLEAQLEKQRKEIAEkheeinSAQLATDLLDskDPKQShmkaQKRGKEQQLDIMNkqYTQLESRLDEilcRI 585
Cdd:PRK10929    26 KQITQELEQAKAAKTPAQAEIVE------ALQSALNWLE--ERKGS----LERAKQYQQVIDN--FPKLSAELRQ---QL 88

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  586 ATETEEIKDLEQQLTdgqiaaNEALKKDLEGVISGLQEylgtIKGQAAQAQNECRKLQDEKETLLQRLTEVkqekdelei 665
Cdd:PRK10929    89 NNERDEPRSVPPNMS------TDALEQEILQVSSQLLE----KSRQAQQEQDRAREISDSLSQLPQQQTEA--------- 149

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  666 vamdaenmRKELAELENALQEQHEVNASLQQAQgdLSAYETELETQ-LKLKDAETSQL----KQELENLvrRTQLEQSVL 740
Cdd:PRK10929   150 --------RRQLNEIERRLQTLGTPNTPLAQAQ--LTALQAESAALkALVDELELAQLsannRQELARL--RSELAKKRS 217

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  741 QtELEKERQSLRDALG-KAQSSEEKQQENSELRAqlKQLQDDNSLLKKQLK---DFQSHLNHVVD--GLIHPEEVAARVD 814
Cdd:PRK10929   218 Q-QLDAYLQALRNQLNsQRQREAERALESTELLA--EQSGDLPKSIVAQFKinrELSQALNQQAQrmDLIASQQRQAASQ 294

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  815 ELRKRLKLGAgeMRIHSP----SDVLGKSLADLQKQFSEILARSQWEKEEAQVRERKLH-EEMALQQEKLA----NGQEE 885
Cdd:PRK10929   295 TLQVRQALNT--LREQSQwlgvSNALGEALRAQVARLPEMPKPQQLDTEMAQLRVQRLRyEDLLNKQPQLRqirqADGQP 372

                          410       420       430
                   ....*....|....*....|....*....|.
gi 1958764989  886 FKQACERALEARIKFDKRQHNARIQQLENEI 916
Cdd:PRK10929   373 LTAEQNRILDAQLRTQRELLNSLLSGGDTLI 403
PRK10929 PRK10929
putative mechanosensitive channel protein; Provisional
 1871-2100 6.53e-05

putative mechanosensitive channel protein; Provisional


Pssm-ID: 236798 [Multi-domain]  Cd Length: 1109  Bit Score: 48.51  E-value: 6.53e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1871 LQKELENTQDHLNLAKQDLMHTTkcQSAL--LSEQAQLQKDVSQWTARLESCQKETETKEQQLQELQDEIRE-----SKL 1943
Cdd:PRK10929    28 ITQELEQAKAAKTPAQAEIVEAL--QSALnwLEERKGSLERAKQYQQVIDNFPKLSAELRQQLNNERDEPRSvppnmSTD 105

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1944 QLDQQ------EMVFQKLQKERESEEQKLVA-SIVSLEQQQGQLERELMDQKSKLEWLLTDVSA-AEGRLRTLQKEERCT 2015
Cdd:PRK10929   106 ALEQEilqvssQLLEKSRQAQQEQDRAREISdSLSQLPQQQTEARRQLNEIERRLQTLGTPNTPlAQAQLTALQAESAAL 185

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 2016 ESLEKMLSQAkqQLS-EREQQLMEKSGDLLalQKEADGMRADFSLLRNQFLTERKKAEKQVAGLKEALKIQRSQLEKNLL 2094
Cdd:PRK10929   186 KALVDELELA--QLSaNNRQELARLRSELA--KKRSQQLDAYLQALRNQLNSQRQREAERALESTELLAEQSGDLPKSIV 261


                   ....*.
gi 1958764989 2095 EQKQEN 2100
Cdd:PRK10929   262 AQFKIN 267
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 667-1084 7.06e-05

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 48.41  E-value: 7.06e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  667 AMDAENMRKELAELENALQEQHEVNASLQQAQGDLSAyetELEtqlKLKDAEtSQLKQELENLVRRTQLEQSVL--QTEL 744
Cdd:COG3096    277 ANERRELSERALELRRELFGARRQLAEEQYRLVEMAR---ELE---ELSARE-SDLEQDYQAASDHLNLVQTALrqQEKI 349

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  745 EKERQSLRDALGKA----QSSEEKQQENSELRAQLKQLQDDNSLLKKQLKDFQSHLNHVVDGLIHPEEVAARVDELRKRl 820
Cdd:COG3096    350 ERYQEDLEELTERLeeqeEVVEEAAEQLAEAEARLEAAEEEVDSLKSQLADYQQALDVQQTRAIQYQQAVQALEKARAL- 428

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  821 kLGAGEMRIHSPSDVLGKSLADLQKQFSEIL-ARSQWEKEEAQVRErklHEEmALQQEKLANGQEEFKQACERALEARIK 899
Cdd:COG3096    429 -CGLPDLTPENAEDYLAAFRAKEQQATEEVLeLEQKLSVADAARRQ---FEK-AYELVCKIAGEVERSQAWQTARELLRR 503

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  900 FDKRQHNA-RIQQLENEIHYLQENLKSMEKIQGL-TDLQLQ-----EADEEKERILAQLQELEKKKRREDARSQEQFLGL 972
Cdd:COG3096    504 YRSQQALAqRLQQLRAQLAELEQRLRQQQNAERLlEEFCQRigqqlDAAEELEELLAELEAQLEELEEQAAEAVEQRSEL 583

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  973 DTELKSLKKAVAASDKLAAAELTiAKEQLKSLhgtvmrinqerAEELQEAERSSREAMQAAKDLSRAEAEIELLQHLLRE 1052
Cdd:COG3096    584 RQQLEQLRARIKELAARAPAWLA-AQDALERL-----------REQSGEALADSQEVTAAMQQLLEREREATVERDELAA 651

                          410       420       430
                   ....*....|....*....|....*....|..
gi 1958764989 1053 REGQFRDEMENAHVGSKGANLQLLeieALKEA 1084
Cdd:COG3096    652 RKQALESQIERLSQPGGAEDPRLL---ALAER 680
HCR pfam07111
Alpha helical coiled-coil rod protein (HCR); This family consists of several mammalian alpha ...
 638-1129 7.82e-05

Alpha helical coiled-coil rod protein (HCR); This family consists of several mammalian alpha helical coiled-coil rod HCR proteins. The function of HCR is unknown but it has been implicated in psoriasis in humans and is thought to affect keratinocyte proliferation.


Pssm-ID: 284517 [Multi-domain]  Cd Length: 749  Bit Score: 47.82  E-value: 7.82e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  638 ECRKLQDE----KETLLQRLTEVKQEKDELEIVAMDAENMRKELAELENALQEQHEVNASLQQAQgdlsayETELETQLK 713
Cdd:pfam07111   74 ELRRLEEEvrllRETSLQQKMRLEAQAMELDALAVAEKAGQAEAEGLRAALAGAEMVRKNLEEGS------QRELEEIQR 147

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  714 LKDAETSQLKQE----LENLVRRTQ-LEQSVLQTELEKErqslrdalGKAQSSEEKQQENSELRAQLKQLQDDnslLKKQ 788
Cdd:pfam07111  148 LHQEQLSSLTQAheeaLSSLTSKAEgLEKSLNSLETKRA--------GEAKQLAEAQKEAELLRKQLSKTQEE---LEAQ 216

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  789 LKDFQSHLNHVVDGLihPEEVAARVDELRKrlklgagemrihspsdvlgKSLADLQKQFSEILARSQWEKEEAQVRERKL 868
Cdd:pfam07111  217 VTLVESLRKYVGEQV--PPEVHSQTWELER-------------------QELLDTMQHLQEDRADLQATVELLQVRVQSL 275

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  869 HEEMALQQEKLANG-------QEEFKQACER----------ALEARIKFDKRQHNARIQQLENEIHYLQENLKSMEKIQG 931
Cdd:pfam07111  276 THMLALQEEELTRKiqpsdslEPEFPKKCRSllnrwrekvfALMVQLKAQDLEHRDSVKQLRGQVAELQEQVTSQSQEQA 355

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  932 LTDLQLQE--ADEEKERI--------LAQLQELEKKKRREDARSQEQF-----------LGLDTELKSLKKAVAASDKLa 990
Cdd:pfam07111  356 ILQRALQDkaAEVEVERMsakglqmeLSRAQEARRRQQQQTASAEEQLkfvvnamsstqIWLETTMTRVEQAVARIPSL- 434

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  991 AAELTIAKEQLKSLHGTVMR---INQERAEELQEAERS-------SREAMQAAKDLSRAEAEIELLQHLLREREGQFRDE 1060
Cdd:pfam07111  435 SNRLSYAVRKVHTIKGLMARkvaLAQLRQESCPPPPPAppvdadlSLELEQLREERNRLDAELQLSAHLIQQEVGRAREQ 514

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1958764989 1061 MEnahvgskganlqlLEIEALKEAMAKQRAEITRLRDVLNLTGT---GKKGGIENVVEEIAELRHAVSAQNE 1129
Cdd:pfam07111  515 GE-------------AERQQLSEVAQQLEQELQRAQESLASVGQqleVARQGQQESTEEAASLRQELTQQQE 573
COG5022 COG5022
Myosin heavy chain [General function prediction only];
1745-2105 8.32e-05

Myosin heavy chain [General function prediction only];


Pssm-ID: 227355 [Multi-domain]  Cd Length: 1463  Bit Score: 48.15  E-value: 8.32e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1745 LQQTAQQQRRELERQRQLLERDRRETE----------------RVRAETQALQSCIECLNKEKEHLQEQCESWEKKSSHA 1808
Cdd:COG5022    764 YLQALKRIKKIQVIQHGFRLRRLVDYElkwrlfiklqpllsllGSRKEYRSYLACIIKLQKTIKREKKLRETEEVEFSLK 843

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1809 KRVL--AATEESNNTEQSKLGQLEVSVRKLQQELELLSqdklalhsdsaQEQQQLQDKREALNSL-QKELENTQDHLNLA 1885
Cdd:COG5022    844 AEVLiqKFGRSLKAKKRFSLLKKETIYLQSAQRVELAE-----------RQLQELKIDVKSISSLkLVNLELESEIIELK 912

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1886 KQ---DLMHTTKCQSALLSEQAQLQKdvsqwTARLE---SCQKETETKEQQLQE----LQDEIRESKLQLDQQEMVFQKL 1955
Cdd:COG5022    913 KSlssDLIENLEFKTELIARLKKLLN-----NIDLEegpSIEYVKLPELNKLHEveskLKETSEEYEDLLKKSTILVREG 987

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1956 QKEREsEEQKLVASIVSLEQQQGQLERELmDQKSKLEWLLTDVSAAEGRLRTLQKEERC---TESLEKMLSQAKQQLSER 2032
Cdd:COG5022    988 NKANS-ELKNFKKELAELSKQYGALQEST-KQLKELPVEVAELQSASKIISSESTELSIlkpLQKLKGLLLLENNQLQAR 1065

                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1958764989 2033 EQQLMEKSGDLLALQKEADGMRADFSLLRNQFLTERKKAEKQVAGLKEALKIQRSQLEKNLLEQKQENSCMQK 2105
Cdd:COG5022   1066 YKALKLRRENSLLDDKQLYQLESTENLLKTINVKDLEVTNRNLVKPANVLQFIVAQMIKLNLLQEISKFLSQL 1138
Golgin_A5 pfam09787
Golgin subfamily A member 5; Members of this family of proteins are involved in maintaining ...
 653-788 8.45e-05

Golgin subfamily A member 5; Members of this family of proteins are involved in maintaining Golgi structure. They stimulate the formation of Golgi stacks and ribbons, and are involved in intra-Golgi retrograde transport. Two main interactions have been characterized: one with RAB1A that has been activated by GTP-binding and another with isoform CASP of CUTL1.


Pssm-ID: 462900 [Multi-domain]  Cd Length: 305  Bit Score: 47.06  E-value: 8.45e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  653 LTEVKQEKD----ELEIVAMDAENMRKELAELENalQEQHEVNASLQQaqgdLSAYETELETQLKLK---DAETSQLKQE 725
Cdd:pfam09787   49 LEELRQERDllreEIQKLRGQIQQLRTELQELEA--QQQEEAESSREQ----LQELEEQLATERSARreaEAELERLQEE 122

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1958764989  726 LENLVRRTQLEQSVLQT---ELEKERQSLRDALGKAQSSEEKQqenSELRAQLKQLQDdnSLLKKQ 788
Cdd:pfam09787  123 LRYLEEELRRSKATLQSrikDREAEIEKLRNQLTSKSQSSSSQ---SELENRLHQLTE--TLIQKQ 183
PRK12704 PRK12704
phosphodiesterase; Provisional
 438-537 1.26e-04

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 47.08  E-value: 1.26e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  438 QLEDTGKQIV-AAQTRLSELHHEIEA-AEQKVLRATQEFKQlEEAIRQKKISEAEKDLLLK--QLSGRLRHLNKLRQEAL 513
Cdd:PRK12704    35 EAEEEAKRILeEAKKEAEAIKKEALLeAKEEIHKLRNEFEK-ELRERRNELQKLEKRLLQKeeNLDRKLELLEKREEELE 113

                           90       100
                   ....*....|....*....|....
gi 1958764989  514 DLEAQLEKQRKEIAEKHEEINSAQ 537
Cdd:PRK12704   114 KKEKELEQKQQELEKKEEELEELI 137
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 466-757 1.27e-04

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 47.23  E-value: 1.27e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  466 KVLRATQEFK--QLEEAirqKKISEAEKDLLLKQLSGRL-RHLNKLRQEaldleaqLEKQRKEIAEKheeinsaqlatdl 542
Cdd:PRK05771    20 EVLEALHELGvvHIEDL---KEELSNERLRKLRSLLTKLsEALDKLRSY-------LPKLNPLREEK------------- 76

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  543 ldskdpkqshMKAQKRGKEQQLDIMNKQYTQLESRLDEILCRIATETEEIKDLEQQLtdgqiaanEALK--KDLEGVISG 620
Cdd:PRK05771    77 ----------KKVSVKSLEELIKDVEEELEKIEKEIKELEEEISELENEIKELEQEI--------ERLEpwGNFDLDLSL 138

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  621 LQ--EYLGTIKGQAAQAQNECRKLQDEKETLLqrltEVKQEKDELEIVAM----DAENMRKELAELENalqEQHEVNASl 694
Cdd:PRK05771   139 LLgfKYVSVFVGTVPEDKLEELKLESDVENVE----YISTDKGYVYVVVVvlkeLSDEVEEELKKLGF---ERLELEEE- 210

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1958764989  695 qqaqGDLSAYETELETQLKLKDAETSQLKQELENLVRRTQLEQSVLQTEL--EKERQSLRDALGK 757
Cdd:PRK05771   211 ----GTPSELIREIKEELEEIEKERESLLEELKELAKKYLEELLALYEYLeiELERAEALSKFLK 271
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1713-2099 1.40e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 47.07  E-value: 1.40e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1713 ELQSLKLQHDQkVVELEKTQVDLLEGKLELESLQQTAQQQRRELERQRQLLErDRRETERVRAETQALQSCIECLNKEKE 1792
Cdd:COG4717     79 ELKEAEEKEEE-YAELQEELEELEEELEELEAELEELREELEKLEKLLQLLP-LYQELEALEAELAELPERLEELEERLE 156

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1793 HLQEQCESWEKKSSHAKRvlaATEESNNTEQSKLGQLEVSVRKLQQELELLSQDKLALHSDSAQEQQQLQDKREALNSLQ 1872
Cdd:COG4717    157 ELRELEEELEELEAELAE---LQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLE 233

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1873 KELENTQDHLNLAKQDLM----------------------------------------HTTKCQSALLSEQAQLQKDVS- 1911
Cdd:COG4717    234 NELEAAALEERLKEARLLlliaaallallglggsllsliltiagvlflvlgllallflLLAREKASLGKEAEELQALPAl 313

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1912 ------QWTARLESCQKETETKEQQLQELQDEIRESKLQLDQQEMVFQKLQKERESEEQKLV---ASIVSLEQ--QQGQL 1980
Cdd:COG4717    314 eeleeeELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQLEELEQEIAALlaeAGVEDEEElrAALEQ 393

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1981 ERELMDQKSKLEWLLTDVSAAEGRLRTLQkEERCTESLEKMLSQAKQQLSEREQQLMEKSGDLLALQKEADGMRADFSLL 2060
Cdd:COG4717    394 AEEYQELKEELEELEEQLEELLGELEELL-EALDEEELEEELEELEEELEELEEELEELREELAELEAELEQLEEDGELA 472

                          410       420       430
                   ....*....|....*....|....*....|....*....
gi 1958764989 2061 RNQFLTERKKAEKQvaglKEALKIQRSQLEKNLLEQKQE 2099
Cdd:COG4717    473 ELLQELEELKAELR----ELAEEWAALKLALELLEEARE 507
PRK10929 PRK10929
putative mechanosensitive channel protein; Provisional
 1815-2043 1.81e-04

putative mechanosensitive channel protein; Provisional


Pssm-ID: 236798 [Multi-domain]  Cd Length: 1109  Bit Score: 46.97  E-value: 1.81e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1815 TEESNNTEQSK-LGQLEVsVRKLQQELELLSQDKLALhsDSAQEQQQLQDKREALN-SLQKELENTQDH-----LNLAKQ 1887
Cdd:PRK10929    29 TQELEQAKAAKtPAQAEI-VEALQSALNWLEERKGSL--ERAKQYQQVIDNFPKLSaELRQQLNNERDEprsvpPNMSTD 105

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1888 DLMHTTKCQSALLSEQAQLQkdvsqwtarlescqketetkeQQLQELQDEIRESKLQLDQQEMVFQKLQKERESEEQKLV 1967
Cdd:PRK10929   106 ALEQEILQVSSQLLEKSRQA---------------------QQEQDRAREISDSLSQLPQQQTEARRQLNEIERRLQTLG 164

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1968 ASIVSLEQQQ-GQLERELMDQKSKLEWL-LTDVSAAE----GRLRT--LQKEErctESLEKMLSQAKQQLS--------- 2030
Cdd:PRK10929   165 TPNTPLAQAQlTALQAESAALKALVDELeLAQLSANNrqelARLRSelAKKRS---QQLDAYLQALRNQLNsqrqreaer 241

                          250
                   ....*....|....*
gi 1958764989 2031 --EREQQLMEKSGDL 2043
Cdd:PRK10929   242 alESTELLAEQSGDL 256
PTZ00108 PTZ00108
DNA topoisomerase 2-like protein; Provisional
 267-535 1.85e-04

DNA topoisomerase 2-like protein; Provisional


Pssm-ID: 240271 [Multi-domain]  Cd Length: 1388  Bit Score: 46.96  E-value: 1.85e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  267 FSLEEIERLEKDLEKKTVETEELKNKQT---------KFLEEIKHQDK--LNKSLKEEAM----------LQKQSCEELE 325
Cdd:PTZ00108  1099 LTKEKVEKLNAELEKKEKELEKLKNTTPkdmwledldKFEEALEEQEEveEKEIAKEQRLksktkgkaskLRKPKLKKKE 1178

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  326 SDLNTKKELLKQKTVELTRACQKQYELEQELAFYKIDAKFEPLNYYPSEYAEMDKSPDESPYIGKSRYKRNMFATETYIV 405
Cdd:PTZ00108  1179 KKKKKSSADKSKKASVVGNSKRVDSDEKRKLDDKPDNKKSNSSGSDQEDDEEQKTKPKKSSVKRLKSKKNNSSKSSEDND 1258

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  406 SDAQAVQVRKMVPDGGQLRhEHAPRAQAPPDVQLEDTGKQIVAAQTRlselhhEIEAAEQKVLRATQEFKQLEE-----A 480
Cdd:PTZ00108  1259 EFSSDDLSKEGKPKNAPKR-VSAVQYSPPPPSKRPDGESNGGSKPSS------PTKKKVKKRLEGSLAALKKKKksekkT 1331

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1958764989  481 IRQKKISEAEKDLLLKQLSGRLRHLNKLRQEALDLEAQLEKQRKEIAEKHEEINS 535
Cdd:PTZ00108  1332 ARKKKSKTRVKQASASQSSRLLRRPRKKKSDSSSEDDDDSEVDDSEDEDDEDDED 1386
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 1896-2101 2.21e-04

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 45.98  E-value: 2.21e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1896 QSALLSEQAQLQKDVSQWTARLESCQKETETKEQQLQELQDEIRESKLQLDQQEMVFQKLQKERESEEQKLVASIVSLEQ 1975
Cdd:COG3883     18 IQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGERARALYR 97

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1976 QQGQLER--ELMDQKSKLEWL-----LTDVSAAEGRLRTLQKEERctESLEKMLSQAKQQLSEREQQLmeksGDLLALQK 2048
Cdd:COG3883     98 SGGSVSYldVLLGSESFSDFLdrlsaLSKIADADADLLEELKADK--AELEAKKAELEAKLAELEALK----AELEAAKA 171

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1958764989 2049 EADGMRADFSLLRNQFLTERKKAEKQVAGLKEALKIQRSQLEKNLLEQKQENS 2101
Cdd:COG3883    172 ELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAA 224
PRK04778 PRK04778
septation ring formation regulator EzrA; Provisional
 452-797 2.43e-04

septation ring formation regulator EzrA; Provisional


Pssm-ID: 179877 [Multi-domain]  Cd Length: 569  Bit Score: 45.98  E-value: 2.43e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  452 RLSELHHEIEAAEQKVLRATQEFKQLEEAIRQKKISEAEKDLLLKQLSGRLRhlnKLRQEAL-------DLEAQLEKQRK 524
Cdd:PRK04778    99 RFRKAKHEINEIESLLDLIEEDIEQILEELQELLESEEKNREEVEQLKDLYR---ELRKSLLanrfsfgPALDELEKQLE 175

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  525 EIAEKHEEinsaqlATDLLDSKDPKQSHMkaqkrgkeqQLDIMNKQYTQLESRLdeilcriatetEEIKDLEQQLTDgqi 604
Cdd:PRK04778   176 NLEEEFSQ------FVELTESGDYVEARE---------ILDQLEEELAALEQIM-----------EEIPELLKELQT--- 226

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  605 aanealkkdlegvisglqeylgTIKGQAAQAQNECRKLQDEK-----ETLLQRLTEVKQEKDELE--IVAMDAENMRKEL 677
Cdd:PRK04778   227 ----------------------ELPDQLQELKAGYRELVEEGyhldhLDIEKEIQDLKEQIDENLalLEELDLDEAEEKN 284

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  678 AELENALQE-----QHEVNA--SLQQAQGDLSAYETELETQLKlkdaetsQLKQELENLVRRTQLEQSVLQT--ELEKER 748
Cdd:PRK04778   285 EEIQERIDQlydilEREVKArkYVEKNSDTLPDFLEHAKEQNK-------ELKEEIDRVKQSYTLNESELESvrQLEKQL 357

                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|
gi 1958764989  749 QSLRDALGK-AQSSEEKQQENSELRAQLKQLQDDNSLLKKQLKDFQSHLN 797
Cdd:PRK04778   358 ESLEKQYDEiTERIAEQEIAYSELQEELEEILKQLEEIEKEQEKLSEMLQ 407
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 1417-1877 2.47e-04

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 46.37  E-value: 2.47e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1417 EDIVDEIECLEKTLLKRRSELREADRLLAEAESELACTKEKTKSAVEKFTDAKRNLLQTESDAEALEKRAQETALNLvka 1496
Cdd:pfam12128  460 PELLLQLENFDERIERAREEQEAANAEVERLQSELRQARKRRDQASEALRQASRRLEERQSALDELELQLFPQAGTL--- 536

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1497 eqqLRLLQADAEDLEQH--KIKQEEILKEINKVVAakdadfqcLNEKKEKLTEELQSLQRDIKAAEVNEDHHLQvlkese 1574
Cdd:pfam12128  537 ---LHFLRKEAPDWEQSigKVISPELLHRTDLDPE--------VWDGSVGGELNLYGVKLDLKRIDVPEWAASE------ 599

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1575 sllQAKRAELETLKSQVTSQQQELAVLDSQLGHRREELLLLQDSLTQAKADLQEA-LTLGETEVAEKCSHIREVKSLLEE 1653
Cdd:pfam12128  600 ---EELRERLDKAEEALQSAREKQAAAEEQLVQANGELEKASREETFARTALKNArLDLRRLFDEKQSEKDKKNKALAER 676

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1654 LSFQKGELN-VHISERRTQLTLIKQEIEKEEENLEVVLQQLSKHKTELKNVADILQLETNELQSLKLQHDQKVVELEKTQ 1732
Cdd:pfam12128  677 KDSANERLNsLEAQLKQLDKKHQAWLEEQKEQKREARTEKQAYWQVVEGALDAQLALLKAAIAARRSGAKAELKALETWY 756

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1733 VDLLEGKLELESLQQTAQQQRRELERQRQLLERDRRET--------ERVRAETQALQSCIECLNKEKEHLQEQCEsweKK 1804
Cdd:pfam12128  757 KRDLASLGVDPDVIAKLKREIRTLERKIERIAVRRQEVlryfdwyqETWLQRRPRLATQLSNIERAISELQQQLA---RL 833

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1805 SSHAKRVLAATEESNNTEQSKLGQLEVSVRKLQQELELLSQDKLALHSDSAQEQ--------QQLQDKREALN-SLQKEL 1875
Cdd:pfam12128  834 IADTKLRRAKLEMERKASEKQQVRLSENLRGLRCEMSKLATLKEDANSEQAQGSigerlaqlEDLKLKRDYLSeSVKKYV 913


                   ..
gi 1958764989 1876 EN 1877
Cdd:pfam12128  914 EH 915
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
670-909 2.68e-04

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 46.16  E-value: 2.68e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  670 AENMRKELAELENA---LQEQ-HEVNASLQQAQGDLSAYETE-----LETQLKLKDAETSQLKQELENLvrRTQLEqsvl 740
Cdd:COG3206    163 EQNLELRREEARKAlefLEEQlPELRKELEEAEAALEEFRQKnglvdLSEEAKLLLQQLSELESQLAEA--RAELA---- 236

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  741 qtELEKERQSLRDALGKAQSSEEKQQENSELRAQLKQLQDDNSLLKKQLKDFQSHlnhvvdgliHPEEVAAR--VDELRK 818
Cdd:COG3206    237 --EAEARLAALRAQLGSGPDALPELLQSPVIQQLRAQLAELEAELAELSARYTPN---------HPDVIALRaqIAALRA 305

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  819 RLKLGAGEMRIHSPSDV--LGKSLADLQKQFSEILARSQwekeEAQVRERKLHEemaLQQEkLANGQEEFKQACERALEA 896
Cdd:COG3206    306 QLQQEAQRILASLEAELeaLQAREASLQAQLAQLEARLA----ELPELEAELRR---LERE-VEVARELYESLLQRLEEA 377

                          250
                   ....*....|...
gi 1958764989  897 RIKFDKRQHNARI 909
Cdd:COG3206    378 RLAEALTVGNVRV 390
PRK00409 PRK00409
recombination and DNA strand exchange inhibitor protein; Reviewed
 1716-1879 3.10e-04

recombination and DNA strand exchange inhibitor protein; Reviewed


Pssm-ID: 234750 [Multi-domain]  Cd Length: 782  Bit Score: 45.97  E-value: 3.10e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1716 SLKLQHDQKVVELEKTQVDllEGKLELESLQQTAQQQRRELERQRQLLERDRRETERVRAEtqalqsciecLNKEKEHLQ 1795
Cdd:PRK00409   494 AKRLGLPENIIEEAKKLIG--EDKEKLNELIASLEELERELEQKAEEAEALLKEAEKLKEE----------LEEKKEKLQ 561

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1796 EQCEswEKKSSHAKRVLAATEESNNTEQSKLGQLevsvRKLQQElellsqdklalhSDSAQEQQQLQDKREALNSLQKEL 1875
Cdd:PRK00409   562 EEED--KLLEEAEKEAQQAIKEAKKEADEIIKEL----RQLQKG------------GYASVKAHELIEARKRLNKANEKK 623


                   ....
gi 1958764989 1876 ENTQ 1879
Cdd:PRK00409   624 EKKK 627
PRK12704 PRK12704
phosphodiesterase; Provisional
 1921-2039 3.58e-04

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 45.54  E-value: 3.58e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1921 QKETETKEQQLQELQDEIRESKLQLDQQEMVFQKLQKERESEEQKLVASIVSLEQQQGQLERELMDQKSKLEwlltdvsa 2000
Cdd:PRK12704    74 EKELRERRNELQKLEKRLLQKEENLDRKLELLEKREEELEKKEKELEQKQQELEKKEEELEELIEEQLQELE-------- 145

                           90       100       110
                   ....*....|....*....|....*....|....*....
gi 1958764989 2001 aegRLRTLQKEERCTESLEKMLSQAKQQLSEREQQLMEK 2039
Cdd:PRK12704   146 ---RISGLTAEEAKEILLEKVEEEARHEAAVLIKEIEEE 181
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1478-1877 3.75e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 45.53  E-value: 3.75e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1478 DAEALEKRAQETALNLVKAEQQLRLLQADAEDLEQHKIKQEEILKEINKVVAAKDadfqcLNEKKEKLTEELQSLQRDIK 1557
Cdd:COG4717     75 ELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLP-----LYQELEALEAELAELPERLE 149

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1558 AAEVNEDHHLQVLKESESL------LQAKRAELETLKSQVTSQQ-----QELAVLDSQLGHRREELLLLQDSLTQAKADL 1626
Cdd:COG4717    150 ELEERLEELRELEEELEELeaelaeLQEELEELLEQLSLATEEElqdlaEELEELQQRLAELEEELEEAQEELEELEEEL 229

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1627 QEALTlgETEVAEKCSHIREVKSLLEELSFQKGELNVHISERRTQLTLIKQEIEKEEENLEVVLQQLSKHKTELKNVADI 1706
Cdd:COG4717    230 EQLEN--ELEAAALEERLKEARLLLLIAAALLALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEEL 307

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1707 LQLET-NELQSLKLQHDQKVVELEKTQvdLLEGKLELESLQQTAQQQRRELERQRQLLERDRRETERVRAETQALQSCIE 1785
Cdd:COG4717    308 QALPAlEELEEEELEELLAALGLPPDL--SPEELLELLDRIEELQELLREAEELEEELQLEELEQEIAALLAEAGVEDEE 385

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1786 CLNKEKEHLQEQCESWEKKSSHAKRVLAATEESNN-TEQSKLGQLEVSVRKLQQELELLSQDKLALHSDSAQEQQQLQD- 1863
Cdd:COG4717    386 ELRAALEQAEEYQELKEELEELEEQLEELLGELEElLEALDEEELEEELEELEEELEELEEELEELREELAELEAELEQl 465

                          410
                   ....*....|....*
gi 1958764989 1864 -KREALNSLQKELEN 1877
Cdd:COG4717    466 eEDGELAELLQELEE 480
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1319-1839 4.18e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 45.68  E-value: 4.18e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1319 EHRDLENEVSRLEDITHHLKSKHQEERwlktsRQHPEKEVEELHRNIDDLVQEKKELELEVEELHRTVERHQQRRDFIDG 1398
Cdd:COG4913    263 RYAAARERLAELEYLRAALRLWFAQRR-----LELLEAELEELRAELARLEAELERLEARLDALREELDELEAQIRGNGG 337

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1399 NVENlmtelEIEKslkhhedivdEIECLEKTLLKRRSELREADRLLAEAESELACTKEKTKSAVEKftdAKRNLLQTESD 1478
Cdd:COG4913    338 DRLE-----QLER----------EIERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAE---AAALLEALEEE 399

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1479 AEALEKRAQETALNLVKAEQQLRLLQADAEDLEQHK----IKQEEILKEINKVVAAKDADFQCLNEKKEKLTEE------ 1548
Cdd:COG4913    400 LEALEEALAEAEAALRDLRRELRELEAEIASLERRKsnipARLLALRDALAEALGLDEAELPFVGELIEVRPEEerwrga 479

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1549 ----LQSLQRDI--------KAAEVNEDHHL------QVLKESESLLQAKRAELETLKSQVTSQQQELAV-LDSQLGHRR 1609
Cdd:COG4913    480 iervLGGFALTLlvppehyaAALRWVNRLHLrgrlvyERVRTGLPDPERPRLDPDSLAGKLDFKPHPFRAwLEAELGRRF 559

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1610 --------EELLLLQDSLTQA--------------KADLQEALTLG---ETEVAEKCSHIREVKSLLEELSFQKGELNVH 1664
Cdd:COG4913    560 dyvcvdspEELRRHPRAITRAgqvkgngtrhekddRRRIRSRYVLGfdnRAKLAALEAELAELEEELAEAEERLEALEAE 639

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1665 ISERRTQLTLikqeiekeeenlevvLQQLSKHKTELKNVADILQletnELQSLKLQHDQkvveLEKTQVDLLEGKLELES 1744
Cdd:COG4913    640 LDALQERREA---------------LQRLAEYSWDEIDVASAER----EIAELEAELER----LDASSDDLAALEEQLEE 696

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1745 LQ---QTAQQQRRELERQRQLLERDRRETERVRAETQALQSciECLNKEKEHLQEQCESW---EKKSSHAKRVLAATEES 1818
Cdd:COG4913    697 LEaelEELEEELDELKGEIGRLEKELEQAEEELDELQDRLE--AAEDLARLELRALLEERfaaALGDAVERELRENLEER 774

                          570       580
                   ....*....|....*....|.
gi 1958764989 1819 NNTEQSKLGQLEVSVRKLQQE 1839
Cdd:COG4913    775 IDALRARLNRAEEELERAMRA 795
RecN COG0497
DNA repair ATPase RecN [Replication, recombination and repair];
453-718 5.03e-04

DNA repair ATPase RecN [Replication, recombination and repair];


Pssm-ID: 440263 [Multi-domain]  Cd Length: 555  Bit Score: 45.07  E-value: 5.03e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  453 LSELHHEIEAAEQKVLRATQEFKQLEEAIRQKkisEAEKDLLLKQLsgrlrhlNKLrqEALDL----EAQLEKQRKEIAE 528
Cdd:COG0497    153 LEELLEEYREAYRAWRALKKELEELRADEAER---ARELDLLRFQL-------EEL--EAAALqpgeEEELEEERRRLSN 220

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  529 KHEEINSAQLATDLLDSKDPkqshmkaqkrGKEQQLDimnkqytQLESRLDeilcRIATETEEIKDLEQQLTDGQIAANE 608
Cdd:COG0497    221 AEKLREALQEALEALSGGEG----------GALDLLG-------QALRALE----RLAEYDPSLAELAERLESALIELEE 279

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  609 ALKkDLEGVISGLQ---EYLGTIKGQAAQAQNECRKLQDEKETLLQRLTEVKQEKDELEIVAMDAENMRKELAELENALQ 685
Cdd:COG0497    280 AAS-ELRRYLDSLEfdpERLEEVEERLALLRRLARKYGVTVEELLAYAEELRAELAELENSDERLEELEAELAEAEAELL 358

                          250       260       270
                   ....*....|....*....|....*....|....
gi 1958764989  686 EQ-HEVNASLQQAQGDLSAYETELETQLKLKDAE 718
Cdd:COG0497    359 EAaEKLSAARKKAAKKLEKAVTAELADLGMPNAR 392
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 635-1127 5.96e-04

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 45.35  E-value: 5.96e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  635 AQNECRKLQDEKETLLQRLTEVKQEKDELEIVAMDAENMRKELAELENALQEQHEVNASLQQAQGDLSAYETELETQLKL 714
Cdd:pfam02463  182 TENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEIESSKQEIE 261

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  715 KDAETSQLKQELENLVRRTQLEQSVLQTELEKERQSLRDALGKAQSSEEKQQENSELRAQLKQLQDDNSLLKKQLKDFQS 794
Cdd:pfam02463  262 KEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEELE 341

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  795 HLNHVVDGLIHPEEVAarVDELRKRLKlgagemrihspsdvlgksLADLQKQFSEILARSQWEKEEAQVRERKLHEEMAL 874
Cdd:pfam02463  342 KELKELEIKREAEEEE--EEELEKLQE------------------KLEQLEEELLAKKKLESERLSSAAKLKEEELELKS 401

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  875 QQEKLANGQ-EEFKQACERALEARIKFDKRQHNARIQQLENEIHYLQENLKSMEKIQGLTDLQLQEADEEKERILAQLQE 953
Cdd:pfam02463  402 EEEKEAQLLlELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVK 481

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  954 LEKKKRREDARSQEQFLG-LDTELKSLKKAVAASDKLAAAELTIAKEQLKSLHGTVMrINQERAEELQEAERSSREAMQA 1032
Cdd:pfam02463  482 LQEQLELLLSRQKLEERSqKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAV-ENYKVAISTAVIVEVSATADEV 560

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1033 AKDLSRAEAEIELLQHLLREREGQFRDEMENAHVGSKGANLQLLEIEALKEAMAKQRAEITRLRDVLNLTGTGKKGGIEN 1112
Cdd:pfam02463  561 EERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKES 640

                          490
                   ....*....|....*
gi 1958764989 1113 VVEEIAELRHAVSAQ 1127
Cdd:pfam02463  641 AKAKESGLRKGVSLE 655
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1316-1761 5.98e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 45.14  E-value: 5.98e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1316 NIPEHRDLENEVSRLEDITHHLKSKHQEERWLKTSRQHPEKEVEELHRNIDDLVQEKKeleleveelhrtVERHQQRRDF 1395
Cdd:COG4717     69 NLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQ------------LLPLYQELEA 136

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1396 IDGNVENLMTELE-IEKSLKHHEDIVDEIECLEKTLLKRRSELREA-DRLLAEAESELACTKEKTKSAVEKFTDAKRNLL 1473
Cdd:COG4717    137 LEAELAELPERLEeLEERLEELRELEEELEELEAELAELQEELEELlEQLSLATEEELQDLAEELEELQQRLAELEEELE 216

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1474 QTESDAEALEKRAQETALNLVKAEQQLRLLQADAE--------DLEQHKIKQEEILKEINKVVAAKDADFQCLNEKKEKL 1545
Cdd:COG4717    217 EAQEELEELEEELEQLENELEAAALEERLKEARLLlliaaallALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLARE 296

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1546 TEELQSLQRDIKAAEVNEDHHLQVLKESESLLQAKRAELETLKSQVTSQQQELAVLDSQLGHRREElLLLQDSLTQAKAD 1625
Cdd:COG4717    297 KASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEE-LQLEELEQEIAAL 375

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1626 LQEALTLGETEVAEKCSHIREVKSLLEELSFQKGELNVHISERR--------TQLTLIKQEIEKEEENLEVVLQQLSKHK 1697
Cdd:COG4717    376 LAEAGVEDEEELRAALEQAEEYQELKEELEELEEQLEELLGELEellealdeEELEEELEELEEELEELEEELEELREEL 455

                          410       420       430       440       450       460
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1958764989 1698 TELKnvADILQLET-NELQSLKLQHDQKVVELEktqvDLLEGKLELESLQQTAQQQRRELERQRQ 1761
Cdd:COG4717    456 AELE--AELEQLEEdGELAELLQELEELKAELR----ELAEEWAALKLALELLEEAREEYREERL 514
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 1930-2096 6.00e-04

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 43.76  E-value: 6.00e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1930 QLQELQDEIRESKLQLDQQEMVFQKLQKERESEEQKLVAsivsLEQQQGQLERELMDQKSKLEWLLTDVSAAEGRLRT-- 2007
Cdd:COG1579     11 DLQELDSELDRLEHRLKELPAELAELEDELAALEARLEA----AKTELEDLEKEIKRLELEIEEVEARIKKYEEQLGNvr 86

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 2008 -------LQKEErctESLEKMLSQAKQQLSEREQQLMEKSGDLLALQKEADGMRADFSLLRNQFLTERKKAEKQVAGLKE 2080
Cdd:COG1579     87 nnkeyeaLQKEI---ESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAELEAELEELEA 163

                          170
                   ....*....|....*.
gi 1958764989 2081 ALKIQRSQLEKNLLEQ 2096
Cdd:COG1579    164 EREELAAKIPPELLAL 179
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1541-1966 6.03e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 44.76  E-value: 6.03e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1541 KKEKLTEELQSLQRDIKAAEVNEDHHLQVLKEseslLQAKRAELETLKSQVTSQQQELAVLDSQLGHRReellllqdsLT 1620
Cdd:COG4717     65 KPELNLKELKELEEELKEAEEKEEEYAELQEE----LEELEEELEELEAELEELREELEKLEKLLQLLP---------LY 131

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1621 QAKADLQEALTLGETEVAEKCSHIREVKSLLEELSfqkgELNVHISERRTQLTlikqeiEKEEENLEVVLQQLSKHKTEL 1700
Cdd:COG4717    132 QELEALEAELAELPERLEELEERLEELRELEEELE----ELEAELAELQEELE------ELLEQLSLATEEELQDLAEEL 201

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1701 KNVADILQLETNELQSLKLQHDQKvveleKTQVDLLEGKLELESLQQTAQQQRRELE----------RQRQLLERDRRET 1770
Cdd:COG4717    202 EELQQRLAELEEELEEAQEELEEL-----EEELEQLENELEAAALEERLKEARLLLLiaaallallgLGGSLLSLILTIA 276

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1771 ERVRAETQALQSCIECLNKEKEHLQEQCESWEKKSSHA-------KRVLAATEESNNTEQSKLGQLEVSVRKLQQELELL 1843
Cdd:COG4717    277 GVLFLVLGLLALLFLLLAREKASLGKEAEELQALPALEeleeeelEELLAALGLPPDLSPEELLELLDRIEELQELLREA 356

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1844 SQDKLALHSDSAQEQQQ------LQDKREALNSL---QKELENTQDHLNLAKQDLMhttkcQSALLSEQAQLQKDVSQWT 1914
Cdd:COG4717    357 EELEEELQLEELEQEIAallaeaGVEDEEELRAAleqAEEYQELKEELEELEEQLE-----ELLGELEELLEALDEEELE 431

                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|....
gi 1958764989 1915 ARLESCQKETETKEQQLQELQDEIRESKLQLDQQE--MVFQKLQKERESEEQKL 1966
Cdd:COG4717    432 EELEELEEELEELEEELEELREELAELEAELEQLEedGELAELLQELEELKAEL 485
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
842-1064 6.42e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 44.91  E-value: 6.42e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  842 DLQKQFSEIL-ARSQWEKEEAQV-----------RERKLHEEMALQQEKLANGQEEFKQACERALEARIkfdkRQHNARI 909
Cdd:COG4913    229 ALVEHFDDLErAHEALEDAREQIellepirelaeRYAAARERLAELEYLRAALRLWFAQRRLELLEAEL----EELRAEL 304

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  910 QQLENEIHYLQENLKSM-EKIQGLTDLQLQEADEEKERILAQLQELEKKK-RREDARSQ--EQFLGLDTELKSLKKAVAA 985
Cdd:COG4913    305 ARLEAELERLEARLDALrEELDELEAQIRGNGGDRLEQLEREIERLERELeERERRRARleALLAALGLPLPASAEEFAA 384

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  986 SDKLAAAELTIAKEQLKSLHgtvmrinqeraEELQEAERSSREAMQAAKDLsraEAEIELLQH---LLREREGQFRDEME 1062
Cdd:COG4913    385 LRAEAAALLEALEEELEALE-----------EALAEAEAALRDLRRELREL---EAEIASLERrksNIPARLLALRDALA 450


                   ..
gi 1958764989 1063 NA 1064
Cdd:COG4913    451 EA 452
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
720-1126 6.51e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 44.76  E-value: 6.51e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  720 SQLKQELENLVRRTQLEQSVLQTELEKERQSLRDALGKAQSSEEKQQENSELRAQLKQLQDDNSLLK------KQLKDFQ 793
Cdd:COG4717     49 ERLEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELReeleklEKLLQLL 128

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  794 SHLNHVVDGLIHPEEVAARVDELRKRLK-LGAGEMRIhspsDVLGKSLADLQKQFSEILARSQWEKEEaqvRERKLHEEM 872
Cdd:COG4717    129 PLYQELEALEAELAELPERLEELEERLEeLRELEEEL----EELEAELAELQEELEELLEQLSLATEE---ELQDLAEEL 201

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  873 ALQQEKLANGQEEFKQACERALEARIKFDKRQHNARIQQLENEIHYLQENLKSMEKIQGLTDLQLQEADEEKER------ 946
Cdd:COG4717    202 EELQQRLAELEEELEEAQEELEELEEELEQLENELEAAALEERLKEARLLLLIAAALLALLGLGGSLLSLILTIagvlfl 281

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  947 ------ILAQLQELEKKKRREDARSQEQFLGL----DTELKSLKKAVAASDKLAAAELTIAKEQLKSLHGTVMRINQERA 1016
Cdd:COG4717    282 vlgllaLLFLLLAREKASLGKEAEELQALPALeeleEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEE 361

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1017 EELQEAERSSREAMQAAKDLSRAEAEIELLQHL-----LREREGQFRDEMENaHVGSKGANLQLLEIEALKEAMAKQRAE 1091
Cdd:COG4717    362 ELQLEELEQEIAALLAEAGVEDEEELRAALEQAeeyqeLKEELEELEEQLEE-LLGELEELLEALDEEELEEELEELEEE 440

                          410       420       430
                   ....*....|....*....|....*....|....*
gi 1958764989 1092 ITRLRDvlnltgtgkkgGIENVVEEIAELRHAVSA 1126
Cdd:COG4717    441 LEELEE-----------ELEELREELAELEAELEQ 464
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1319-1556 6.53e-04

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 45.06  E-value: 6.53e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1319 EHRDLENEVSRLEDITHH----LKSKHQEERWLKTSRQHPEKEVEELHRNIDDLVQEKKELELEVEELHRTVERHQQRrd 1394
Cdd:TIGR02169  799 ELSKLEEEVSRIEARLREieqkLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAA-- 876

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1395 fidgnvenlmtELEIEKSLKHhedivdeiecLEKTLLKRRSELREADRLLAEAESELactkEKTKSAVEKFTDAKRNLLQ 1474
Cdd:TIGR02169  877 -----------LRDLESRLGD----------LKKERDELEAQLRELERKIEELEAQI----EKKRKRLSELKAKLEALEE 931

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1475 TESDAEALEKRAQE---TALNLVKAEQQLRLLQADAEDLEQHKIKQEEILKEINKvvaakdaDFQCLNEKKEKLTEELQS 1551
Cdd:TIGR02169  932 ELSEIEDPKGEDEEipeEELSLEDVQAELQRVEEEIRALEPVNMLAIQEYEEVLK-------RLDELKEKRAKLEEERKA 1004


                   ....*
gi 1958764989 1552 LQRDI 1556
Cdd:TIGR02169 1005 ILERI 1009
Cast pfam10174
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ...
 1709-2050 8.87e-04

RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.


Pssm-ID: 431111 [Multi-domain]  Cd Length: 766  Bit Score: 44.43  E-value: 8.87e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1709 LETNELQSLKLQHDQKVVELEKTQVDLLEGKLELESLQQTA----QQQRRELER-------QRQLLERDRRETERVRAET 1777
Cdd:pfam10174  113 LTEENFRRLQSEHERQAKELFLLRKTLEEMELRIETQKQTLgardESIKKLLEMlqskglpKKSGEEDWERTRRIAEAEM 192

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1778 QA--LQSCIECLNKEKEHLQE------QCESWEKKSSHAKRVLAATEesnnteqSKLGQLEVSVRKLQQELELLSQDKLa 1849
Cdd:pfam10174  193 QLghLEVLLDQKEKENIHLREelhrrnQLQPDPAKTKALQTVIEMKD-------TKISSLERNIRDLEDEVQMLKTNGL- 264

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1850 LHSDSAQEQ----------------------QQLQDKREALNSLQKELENTQDHLNLAKQDLMHTTKCQSALLSEQAQLQ 1907
Cdd:pfam10174  265 LHTEDREEEikqmevykshskfmknkidqlkQELSKKESELLALQTKLETLTNQNSDCKQHIEVLKESLTAKEQRAAILQ 344

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1908 KDVSQWTARLESCQKETETKEQQLQELQD-------EIRESKLQLDQQEMVFQKLQKEreseeqklvasIVSLEQQQGQL 1980
Cdd:pfam10174  345 TEVDALRLRLEEKESFLNKKTKQLQDLTEekstlagEIRDLKDMLDVKERKINVLQKK-----------IENLQEQLRDK 413

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1981 ERELMDQKSKLEWLLTDVSAAEGRLRTLQ-------------KEERC---------TESLEKMLSQAKQQLSEREQQLME 2038
Cdd:pfam10174  414 DKQLAGLKERVKSLQTDSSNTDTALTTLEealsekeriierlKEQREredrerleeLESLKKENKDLKEKVSALQPELTE 493

                          410
                   ....*....|..
gi 1958764989 2039 KSGDLLALQKEA 2050
Cdd:pfam10174  494 KESSLIDLKEHA 505
PRK12704 PRK12704
phosphodiesterase; Provisional
 1495-1598 9.72e-04

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 44.00  E-value: 9.72e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1495 KAEQQLRLLQADAED-LEQHKIKQEEILKEinKVVAAKDADF----QCLNEKKEKlTEELQSLQRDIKAAEVNEDHHLQV 1569
Cdd:PRK12704    28 IAEAKIKEAEEEAKRiLEEAKKEAEAIKKE--ALLEAKEEIHklrnEFEKELRER-RNELQKLEKRLLQKEENLDRKLEL 104

                           90       100
                   ....*....|....*....|....*....
gi 1958764989 1570 LKESESLLQAKRAELETLKSQVTSQQQEL 1598
Cdd:PRK12704   105 LEKREEELEKKEKELEQKQQELEKKEEEL 133
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 438-1052 1.05e-03

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 44.27  E-value: 1.05e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  438 QLEDTGKQIVAAQTRLSELHHEIEAAEQKVLRATQEFKQLEEAIRQKKISEAEKDLLlkQLSGRLRHLNKLRQEALDLEA 517
Cdd:TIGR00606  266 KLDNEIKALKSRKKQMEKDNSELELKMEKVFQGTDEQLNDLYHNHQRTVREKERELV--DCQRELEKLNKERRLLNQEKT 343

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  518 QLEKQRKEIAEKHEEINSAQLATDLLDSKDPKQSHMKAQKRGKEQQLDIMNKQYTQLESRLDEilcrIATETEEIKDLEQ 597
Cdd:TIGR00606  344 ELLVEQGRLQLQADRHQEHIRARDSLIQSLATRLELDGFERGPFSERQIKNFHTLVIERQEDE----AKTAAQLCADLQS 419

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  598 QLTDGQIAANEALKKdlegvisglqeylgtIKGQAAQAQNECRKLQDEKETLLQRLTEVKQEKDELEIVAMDAENMRKEL 677
Cdd:TIGR00606  420 KERLKQEQADEIRDE---------------KKGLGRTIELKKEILEKKQEELKFVIKELQQLEGSSDRILELDQELRKAE 484

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  678 AEL----ENALQEQHEVNA-SLQQAQGDLSAYETELETQLKLKDAETSQLKQeLENLVRRTQLEQSVLQTELEKERQSLR 752
Cdd:TIGR00606  485 RELskaeKNSLTETLKKEVkSLQNEKADLDRKLRKLDQEMEQLNHHTTTRTQ-MEMLTKDKMDKDEQIRKIKSRHSDELT 563

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  753 DALGKAQSSEEKQQENSELRAQLKQLQDDNSLLKKQLKDFQSHLNHVVDGLIHPEE-----------------VAARVDE 815
Cdd:TIGR00606  564 SLLGYFPNKKQLEDWLHSKSKEINQTRDRLAKLNKELASLEQNKNHINNELESKEEqlssyedklfdvcgsqdEESDLER 643

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  816 LRKRLKLGAGEMRIHSPSDVLGKS----LADLQKQFSEILARSQWEKEEAQVRERKLHEEMALQQEKLANGQEEFKQACE 891
Cdd:TIGR00606  644 LKEEIEKSSKQRAMLAGATAVYSQfitqLTDENQSCCPVCQRVFQTEAELQEFISDLQSKLRLAPDKLKSTESELKKKEK 723

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  892 RALEARIKFDKRQhnARIQQLENEIHYLQENLKSMEkiqglTDLQLQEAD-EEKERILAQLQELEK--KKRREDARSQEQ 968
Cdd:TIGR00606  724 RRDEMLGLAPGRQ--SIIDLKEKEIPELRNKLQKVN-----RDIQRLKNDiEEQETLLGTIMPEEEsaKVCLTDVTIMER 796

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  969 FlglDTELKSLKKAVAAsdklaaaelTIAKEQLKSLHGTVMRINQERAEELQEAERSSREAMQAAKDLSRAEAEIELLQH 1048
Cdd:TIGR00606  797 F---QMELKDVERKIAQ---------QAAKLQGSDLDRTVQQVNQEKQEKQHELDTVVSKIELNRKLIQDQQEQIQHLKS 864


                   ....
gi 1958764989 1049 LLRE 1052
Cdd:TIGR00606  865 KTNE 868
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 269-969 1.10e-03

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 44.19  E-value: 1.10e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  269 LEEIERLEKDLEKKTVETEELKNKQTKFLEEIKHQDKLNKSLKEEAMLQKQSCEELESDLNTKKELLKQKTVELTRACQK 348
Cdd:TIGR00618  169 LMNLFPLDQYTQLALMEFAKKKSLHGKAELLTLRSQLLTLCTPCMPDTYHERKQVLEKELKHLREALQQTQQSHAYLTQK 248

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  349 QYELEQELAFYK----IDAKFEPLNYYPSEYAEMDKSPDESPYIGK-SRYKRNMFATETYIVSDAQAVQVRKMvpDGGQL 423
Cdd:TIGR00618  249 REAQEEQLKKQQllkqLRARIEELRAQEAVLEETQERINRARKAAPlAAHIKAVTQIEQQAQRIHTELQSKMR--SRAKL 326

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  424 RHEHAPRAQAPPDVQLEDTGKQIVAAQTRLSELHHEIEAAEQKVLRATQEFKQLEEAIRQKKISEAEKDLLLKQLSGRLR 503
Cdd:TIGR00618  327 LMKRAAHVKQQSSIEEQRRLLQTLHSQEIHIRDAHEVATSIREISCQQHTLTQHIHTLQQQKTTLTQKLQSLCKELDILQ 406

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  504 HLNKlRQEALDLEAQLEKQRKEIAEKHEEINSAQLA---------TDLLDSKDPKQSHMKAQKRGKEQQLDIMnKQYTQL 574
Cdd:TIGR00618  407 REQA-TIDTRTSAFRDLQGQLAHAKKQQELQQRYAElcaaaitctAQCEKLEKIHLQESAQSLKEREQQLQTK-EQIHLQ 484

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  575 ESRLDEILCRIATETEE--------IKDLEQQLTD-GQIAANEALKKDLEGVISGLQEYLGTIKGQAAQAQNECRKLQDE 645
Cdd:TIGR00618  485 ETRKKAVVLARLLELQEepcplcgsCIHPNPARQDiDNPGPLTRRMQRGEQTYAQLETSEEDVYHQLTSERKQRASLKEQ 564

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  646 KETLLQRLTEVKQEKDEleiVAMDAENMRKELAELENALQEQHEVNASLQQAQgdlsaYETELETQLKLKDAETSQLKQE 725
Cdd:TIGR00618  565 MQEIQQSFSILTQCDNR---SKEDIPNLQNITVRLQDLTEKLSEAEDMLACEQ-----HALLRKLQPEQDLQDVRLHLQQ 636

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  726 LENLVRRTQLEQSVLQTELEKERQ---SLRDALGKAQSSEEKQQENSELRAQLKQLQDDNSLLKKQLKDFQSHLNHVVDG 802
Cdd:TIGR00618  637 CSQELALKLTALHALQLTLTQERVrehALSIRVLPKELLASRQLALQKMQSEKEQLTYWKEMLAQCQTLLRELETHIEEY 716

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  803 LIHPEEVAarvdelrkrLKLGAGEMRIHSPSDVLGKSLADLQKQFSEILARSqwEKEEAQVRERKLHEEMALQQEKLANG 882
Cdd:TIGR00618  717 DREFNEIE---------NASSSLGSDLAAREDALNQSLKELMHQARTVLKAR--TEAHFNNNEEVTAALQTGAELSHLAA 785

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  883 QEEFKQACERALEARIKFDKRQHNARIQqleneiHYLQENLKSMEKIQG---LTDLQLQEADEEKERILAQLQELEKKKR 959
Cdd:TIGR00618  786 EIQFFNRLREEDTHLLKTLEAEIGQEIP------SDEDILNLQCETLVQeeeQFLSRLEEKSATLGEITHQLLKYEECSK 859

                          730
                   ....*....|
gi 1958764989  960 REDARSQEQF 969
Cdd:TIGR00618  860 QLAQLTQEQA 869
LRR_4 pfam12799
Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a ...
 170-213 1.12e-03

Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a number of proteins with diverse functions and cellular locations. These repeats are usually involved in protein-protein interactions. Each Leucine Rich Repeat is composed of a beta-alpha unit. These units form elongated non-globular structures. Leucine Rich Repeats are often flanked by cysteine rich domains.


Pssm-ID: 463713 [Multi-domain]  Cd Length: 44  Bit Score: 38.38  E-value: 1.12e-03
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*
gi 1958764989  170 NLQKLNLAGNEIEHIPgwFSKKLKSLRVLNLKGN-KISSLQDVSK 213
Cdd:pfam12799    2 NLEVLDLSNNQITDIP--PLAKLPNLETLDLSGNnKITDLSDLAN 44
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
669-908 1.13e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 44.14  E-value: 1.13e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  669 DAENMRKELAELENA------LQEQHEVnasLQQAQGDLSAYEtELETQLKLKDAETSQLKQElenlvrRTQLEQSVLQT 742
Cdd:COG4913    226 AADALVEHFDDLERAhealedAREQIEL---LEPIRELAERYA-AARERLAELEYLRAALRLW------FAQRRLELLEA 295

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  743 ELEKERQSLRDALGKAQSSEEKQQENSELRAQLKQLQDDNSL-----LKKQLKDFQSHLnhvvdglihpEEVAARVDELR 817
Cdd:COG4913    296 ELEELRAELARLEAELERLEARLDALREELDELEAQIRGNGGdrleqLEREIERLEREL----------EERERRRARLE 365

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  818 KRLKlgagemrihspsdVLGKSLADLQKQFSEILARSQWEKEEAQVRERKLHEEMALQQEKLANGQEEFKQACE--RALE 895
Cdd:COG4913    366 ALLA-------------ALGLPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAeiASLE 432

                          250
                   ....*....|....
gi 1958764989  896 ARIK-FDKRQHNAR 908
Cdd:COG4913    433 RRKSnIPARLLALR 446
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 507-1106 1.14e-03

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 44.40  E-value: 1.14e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  507 KLRQEALDLEAQLEkqrkeiaEKHEEINSAQLATDLLDSKDPKqshMKAQKRGKEQQLDIMNKQYTQLESRLDEILCRIA 586
Cdd:pfam01576  100 KMQQHIQDLEEQLD-------EEEAARQKLQLEKVTTEAKIKK---LEEDILLLEDQNSKLSKERKLLEERISEFTSNLA 169

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  587 TETEEIKDL-------EQQLTDGQIAAN---------EALKKDLEGVISGLQEYLGTIKGQAAQAQNECRKLQDEKETLL 650
Cdd:pfam01576  170 EEEEKAKSLsklknkhEAMISDLEERLKkeekgrqelEKAKRKLEGESTDLQEQIAELQAQIAELRAQLAKKEEELQAAL 249

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  651 QRLTEVKQEKDELEIVAMDAENMRKELAE-LENALQEQHEVNASLQQAQGDLSAYETELETQLKLKDAET---SQLKQEL 726
Cdd:pfam01576  250 ARLEEETAQKNNALKKIRELEAQISELQEdLESERAARNKAEKQRRDLGEELEALKTELEDTLDTTAAQQelrSKREQEV 329

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  727 ENLVRRTQLEQSVLQTELEKERQSLRDAL----------GKAQSSEEK-----QQENSELRAQLKQLQDDNS-------L 784
Cdd:pfam01576  330 TELKKALEEETRSHEAQLQEMRQKHTQALeelteqleqaKRNKANLEKakqalESENAELQAELRTLQQAKQdsehkrkK 409

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  785 LKKQLKDFQSHLNhvvDGLIHPEEVAARVDELRKRLKLGAGEM-RIHSPSDVLGKSLADLQKQF---SEILARSQWEKEE 860
Cdd:pfam01576  410 LEGQLQELQARLS---ESERQRAELAEKLSKLQSELESVSSLLnEAEGKNIKLSKDVSSLESQLqdtQELLQEETRQKLN 486

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  861 AQVRERKLHEEMALQQEKLANgQEEFKQACERALEArikfdkrqHNARIQQLENEIHYLQENLKSMEKIQGLTDLQLQEA 940
Cdd:pfam01576  487 LSTRLRQLEDERNSLQEQLEE-EEEAKRNVERQLST--------LQAQLSDMKKKLEEDAGTLEALEEGKKRLQRELEAL 557

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  941 DEEKERILAQLQELEKKKRREDARSQEQFLGLDTE---LKSLKKAVAASDKLAAAELTIAkeqlkslhgtvmrinQERAE 1017
Cdd:pfam01576  558 TQQLEEKAAAYDKLEKTKNRLQQELDDLLVDLDHQrqlVSNLEKKQKKFDQMLAEEKAIS---------------ARYAE 622

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1018 ELQEAERSSREAMQAAKDLSRAEAEIELLQHLLREREGQFRDEMENAhVGSK---GANLQLLE--IEALKEAMAKQRAEI 1092
Cdd:pfam01576  623 ERDRAEAEAREKETRALSLARALEEALEAKEELERTNKQLRAEMEDL-VSSKddvGKNVHELErsKRALEQQVEEMKTQL 701

                          650
                   ....*....|....
gi 1958764989 1093 TRLRDVLNLTGTGK 1106
Cdd:pfam01576  702 EELEDELQATEDAK 715
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 438-790 1.24e-03

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 43.86  E-value: 1.24e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  438 QLEDTGKQIVAAQTRLSELHHEIEAAEQKVLRATQEFKQLEEAIRQKkisEAEKDLLLKQLSgrlrhlnklrqealDLEA 517
Cdd:TIGR04523  371 EIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKL---QQEKELLEKEIE--------------RLKE 433

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  518 QLEKQRKEIAEKHEEINSAQLATDLLDSKDPKQshmkaqkrgkEQQLDIMNKQYTQLESRLDEILCRIATETEEIKDLEQ 597
Cdd:TIGR04523  434 TIIKNNSEIKDLTNQDSVKELIIKNLDNTRESL----------ETQLKVLSRSINKIKQNLEQKQKELKSKEKELKKLNE 503

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  598 QltdgqiaanealKKDLEGVISGLqeylgtiKGQAAQAQNECRKLQDEKETLLQRLTEVKQEKDELEIVaMDAENMRKEL 677
Cdd:TIGR04523  504 E------------KKELEEKVKDL-------TKKISSLKEKIEKLESEKKEKESKISDLEDELNKDDFE-LKKENLEKEI 563

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  678 AELENALQEQHEVNASLQQAQgdlsayeTELETQLKLKDAETSQLKQELEnlvrrtqlEQSVLQTELEKErqslrdalgk 757
Cdd:TIGR04523  564 DEKNKEIEELKQTQKSLKKKQ-------EEKQELIDQKEKEKKDLIKEIE--------EKEKKISSLEKE---------- 618

                          330       340       350
                   ....*....|....*....|....*....|...
gi 1958764989  758 aqsSEEKQQENSELRAQLKQLQDDNSLLKKQLK 790
Cdd:TIGR04523  619 ---LEKAKKENEKLSSIIKNIKSKKNKLKQEVK 648
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
437-786 1.25e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 43.99  E-value: 1.25e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  437 VQLEDTGKQIVAAQTRLSELHHEIEAAEQKVLRATQEFKQLEEAIRQKKISEAEKDLLLKQLS-GRLRHLNKLRQEALDL 515
Cdd:COG4717    125 LQLLPLYQELEALEAELAELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSlATEEELQDLAEELEEL 204

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  516 EAQLEKQRKEIAEKHEEINSAQLATDLLDSKDPKQSHMKAQKRGKEQQLDI---------MNKQYTQLESRLDEILCRIA 586
Cdd:COG4717    205 QQRLAELEEELEEAQEELEELEEELEQLENELEAAALEERLKEARLLLLIAaallallglGGSLLSLILTIAGVLFLVLG 284

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  587 TETEEIKDLEQQLTDGQIAANEALKKDLEGVIS--GLQEYLGTIKGQAAQAQNECRKLQDEKETLLQRLTEVKQEKDELE 664
Cdd:COG4717    285 LLALLFLLLAREKASLGKEAEELQALPALEELEeeELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQ 364

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  665 IVAMDAEN----------MRKELAELENALQEQHEVNASLQQAQGDLSAYETELETQLKLKDAEtsQLKQELENLVRRTQ 734
Cdd:COG4717    365 LEELEQEIaallaeagveDEEELRAALEQAEEYQELKEELEELEEQLEELLGELEELLEALDEE--ELEEELEELEEELE 442

                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1958764989  735 LEQSVLQtELEKERQSLRDALGKAQSS---EEKQQENSELRAQLKQLQDDNSLLK 786
Cdd:COG4717    443 ELEEELE-ELREELAELEAELEQLEEDgelAELLQELEELKAELRELAEEWAALK 496
PRK12704 PRK12704
phosphodiesterase; Provisional
 857-1031 1.28e-03

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 43.61  E-value: 1.28e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  857 EKEEAQVRERKLHEEMALQQEKLANGQEEFKQaceraLEARIKFDKRQHNARIQQLENEIHYLQENLKsmEKIQGLTDLQ 936
Cdd:PRK12704    37 EEEAKRILEEAKKEAEAIKKEALLEAKEEIHK-----LRNEFEKELRERRNELQKLEKRLLQKEENLD--RKLELLEKRE 109

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  937 lQEADEEKERILAQLQELEKKKRREDARSQEQflglDTELKSLkkavaasdklaaAELTI--AKEQL------KSLHGTV 1008
Cdd:PRK12704   110 -EELEKKEKELEQKQQELEKKEEELEELIEEQ----LQELERI------------SGLTAeeAKEILlekveeEARHEAA 172

                          170       180
                   ....*....|....*....|....*..
gi 1958764989 1009 MRINQERAEELQEAERSSRE----AMQ 1031
Cdd:PRK12704   173 VLIKEIEEEAKEEADKKAKEilaqAIQ 199
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
1712-1993 1.28e-03

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 43.35  E-value: 1.28e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1712 NELQSLKLQHDQKVVELEKTQVDLLEGKLELESLQQTAQQQRRELERQRQLLERDRRETERVRAETQALQSCIECLNKEK 1791
Cdd:COG4372     45 EELEQLREELEQAREELEQLEEELEQARSELEQLEEELEELNEQLQAAQAELAQAQEELESLQEEAEELQEELEELQKER 124

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1792 EHLQEQCESWEKKSSHAKRVLAATEESNNTEQSKLGQLEVSVRKLQQELELLSQDKL--------------ALHSDSAQE 1857
Cdd:COG4372    125 QDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEELAALEQELQALSEAEAeqaldellkeanrnAEKEEELAE 204

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1858 QQQLQDKREALNSLQKELENTQDHLNLAKQDLMHTTKCQSALLSEQAQLQKDVSQWTARLESCQKETETKEQQLQELQDE 1937
Cdd:COG4372    205 AEKLIESLPRELAEELLEAKDSLEAKLGLALSALLDALELEEDKEELLEEVILKEIEELELAILVEKDTEEEELEIAALE 284

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1958764989 1938 IRESKLQLDQQEMVFQKLQKERESEEQKLVASIVSLEQQQGQLERELMDQKSKLEW 1993
Cdd:COG4372    285 LEALEEAALELKLLALLLNLAALSLIGALEDALLAALLELAKKLELALAILLAELA 340
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1573-1814 1.29e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 43.60  E-value: 1.29e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1573 SESLLQAKRAELETLKSQVTSQQQELAVLDSQLGHRREELLLLQDSLTQAKADLQEAltlgETEvaekcshIREVKSLLE 1652
Cdd:COG4942     18 QADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRAL----EQE-------LAALEAELA 86

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1653 ELSFQKGELNVHISERRTQLTLIKQEIEKEEENLEVVLQQLSKHKTELKNVADILQLETNELQSLKLQHDQKVVELEKTQ 1732
Cdd:COG4942     87 ELEKEIAELRAELEAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALR 166

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1733 VDLLEgklELESLQQTAQQQRRELERQRQLLERDRRETERVRAETQALQSCIECLNKEKEHLQEQCESWEKKSSHAKRVL 1812
Cdd:COG4942    167 AELEA---ERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERT 243


                   ..
gi 1958764989 1813 AA 1814
Cdd:COG4942    244 PA 245
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 1824-1984 1.29e-03

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 42.60  E-value: 1.29e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1824 SKLGQLEVSVRKLQQELELLSQDKLALHSDSAQEQQQLQDKREALNSLQKELENTQDHLNLAKQDLMHTTKcqsalLSEQ 1903
Cdd:COG1579     17 SELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLGNVRN-----NKEY 91

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1904 AQLQKDVSQWTARLESCQKETETKEQQLQELQDEIRESKLQLDQQEMVFQKLQKERESEEQKLVASIVSLEQQQGQLERE 1983
Cdd:COG1579     92 EALQKEIESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAELEAELEELEAEREELAAK 171


                   .
gi 1958764989 1984 L 1984
Cdd:COG1579    172 I 172
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 1848-2081 1.30e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 43.67  E-value: 1.30e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1848 LALHSDSAQEQQQLQDKREALNSLQKELENTQDHLNLAKQDLmhttkcqSALLSEQAQLQKDVSQWTARLESCQKETETK 1927
Cdd:COG3883      5 ALAAPTPAFADPQIQAKQKELSELQAELEAAQAELDALQAEL-------EELNEEYNELQAELEALQAEIDKLQAEIAEA 77

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1928 EQQLQELQDEIRESKLQLDQQEMVFQKLQKERESEE-QKLVASIVSLEQ---QQGQLERELMDQKSKLEWLLTDVSAAEG 2003
Cdd:COG3883     78 EAEIEERREELGERARALYRSGGSVSYLDVLLGSESfSDFLDRLSALSKiadADADLLEELKADKAELEAKKAELEAKLA 157

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1958764989 2004 RLRTLQKEerctesLEKMLSQAKQQLSEREQQLMEKSGDLLALQKEADGMRADFSLLRNQFLTERKKAEKQVAGLKEA 2081
Cdd:COG3883    158 ELEALKAE------LEAAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAA 229
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 1426-1984 1.31e-03

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 44.27  E-value: 1.31e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1426 LEKTLLKRRSELREADRLLAEAESELAcTKEKTKSAVEKFTDAKRNLLQTESD-------AEALEKRAQETALNLVKAEQ 1498
Cdd:TIGR00606  575 LEDWLHSKSKEINQTRDRLAKLNKELA-SLEQNKNHINNELESKEEQLSSYEDklfdvcgSQDEESDLERLKEEIEKSSK 653

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1499 QLRLLQADAEDLEQHKikqEEILKEINKVVAAKDADFQclneKKEKLTEELQSLQRDIKAAEVNedhhlqvLKESESLLQ 1578
Cdd:TIGR00606  654 QRAMLAGATAVYSQFI---TQLTDENQSCCPVCQRVFQ----TEAELQEFISDLQSKLRLAPDK-------LKSTESELK 719

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1579 AKRAELETLKSQVTSQQQELAVLDSQLGHRREELLLLQDSLTQAKADLQEALTLGETEVAEKCShireVKSLLEELS-FQ 1657
Cdd:TIGR00606  720 KKEKRRDEMLGLAPGRQSIIDLKEKEIPELRNKLQKVNRDIQRLKNDIEEQETLLGTIMPEEES----AKVCLTDVTiME 795

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1658 KGELNVHISERRtqltLIKQEIEKEEENLEVVLQQLSKHKTELKNVADILQLETNELQSLKLQHDQKVVELEKTQVDLLE 1737
Cdd:TIGR00606  796 RFQMELKDVERK----IAQQAAKLQGSDLDRTVQQVNQEKQEKQHELDTVVSKIELNRKLIQDQQEQIQHLKSKTNELKS 871

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1738 GKLELeslqQTAQQQRRELERQRQLLERDrretervraetqaLQSCIECLNKEKEHLQEQCESWEKKSSHAKRVLAATEE 1817
Cdd:TIGR00606  872 EKLQI----GTNLQRRQQFEEQLVELSTE-------------VQSLIREIKDAKEQDSPLETFLEKDQQEKEELISSKET 934

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1818 SNNTEQSKLGQLEVSVRKL---QQELELLSQDKlalhsdsaqEQQQLQDKREALNSLQKELENTQDHLNLAKQDL----- 1889
Cdd:TIGR00606  935 SNKKAQDKVNDIKEKVKNIhgyMKDIENKIQDG---------KDDYLKQKETELNTVNAQLEECEKHQEKINEDMrlmrq 1005

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1890 -MHTTKCQSALLSEQAQLQKdvsqwtarlescqKETETKEQQLQELQDEIRESKLQLDQQEMVFQKLQKERES---EEQK 1965
Cdd:TIGR00606 1006 dIDTQKIQERWLQDNLTLRK-------------RENELKEVEEELKQHLKEMGQMQVLQMKQEHQKLEENIDLikrNHVL 1072

                          570
                   ....*....|....*....
gi 1958764989 1966 LVASIVSLEQQQGQLEREL 1984
Cdd:TIGR00606 1073 ALGRQKGYEKEIKHFKKEL 1091
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 438-725 1.31e-03

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 43.90  E-value: 1.31e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  438 QLEDTGKQIVAAQTRLSELHHEIEAAEQKVLRA-----TQEFKQLEEAIRQKKISEAEKDLLLKQLSGRLRHLNKLRQEA 512
Cdd:TIGR02169  759 ELKELEARIEELEEDLHKLEEALNDLEARLSHSripeiQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQEL 838

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  513 LDLEAQLEKQRKEIAEKHEEINsaqlatdlldskdpkqshmkAQKRGKEQQLDIMNKQYTQLESRLDEIlcriateTEEI 592
Cdd:TIGR02169  839 QEQRIDLKEQIKSIEKEIENLN--------------------GKKEELEEELEELEAALRDLESRLGDL-------KKER 891

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  593 KDLEQQLTDGQIAANEALKK--DLEGVISGLQEYLGTIKGQAAQAQNECRKLQDEKETLLQrLTEVKQEKDELE--IVAM 668
Cdd:TIGR02169  892 DELEAQLRELERKIEELEAQieKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEELS-LEDVQAELQRVEeeIRAL 970

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1958764989  669 DAENMRkelaelenALQEQHEVNASLQQAQGDLSAYETElETQLKLKDAETSQLKQE 725
Cdd:TIGR02169  971 EPVNML--------AIQEYEEVLKRLDELKEKRAKLEEE-RKAILERIEEYEKKKRE 1018
PTZ00121 PTZ00121
MAEBL; Provisional
 273-770 1.57e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 43.98  E-value: 1.57e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  273 ERLEKDLEKKTVETEELKNKQTKFLEEIKHQDKLNKSLKEEAmlqKQSCEELESDLNTKKELLKQKTVELTRACQKQYEL 352
Cdd:PTZ00121  1293 DEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAA---KKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAA 1369

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  353 EQELAFYKIDAKFEPLNYYPSEYAEMDKSPDESPYIGKSRYKRNMFATETYIVSDAQAVQVRKmvPDGGQLRHEHAPRAQ 432
Cdd:PTZ00121  1370 EKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKK--ADEAKKKAEEAKKAD 1447

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  433 APPDVQLEDTGKQIVAAQTRLSELHHEIEAAEQKVLRATQEFKQLEEAirQKKISEAEKDLLLKQLSGRLRHLNKLRQeA 512
Cdd:PTZ00121  1448 EAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEA--KKKADEAKKAAEAKKKADEAKKAEEAKK-A 1524

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  513 LDLEAQLEKQRKEIAEKHEEINSAQLATDLLDSKDPKQSHMKAQKRGKEQQldimnkqyTQLESRLDEILCRIatETEEI 592
Cdd:PTZ00121  1525 DEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEED--------KNMALRKAEEAKKA--EEARI 1594

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  593 KDLEQQLTDGQIAANEALKKDLEGVISGlqeylgtikgqaaqaqNECRKLQDEKETLLQRLTEVKQEKDELEIVAMDAEN 672
Cdd:PTZ00121  1595 EEVMKLYEEEKKMKAEEAKKAEEAKIKA----------------EELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEE 1658

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  673 MRKELAELENALQEQHEVNASLQQAQGDlsayETELETQLKLKDAETSQLKQelenlVRRTQLEQSVLQTELEKERQSLR 752
Cdd:PTZ00121  1659 NKIKAAEEAKKAEEDKKKAEEAKKAEED----EKKAAEALKKEAEEAKKAEE-----LKKKEAEEKKKAEELKKAEEENK 1729

                          490
                   ....*....|....*...
gi 1958764989  753 DALGKAQSSEEKQQENSE 770
Cdd:PTZ00121  1730 IKAEEAKKEAEEDKKKAE 1747
46 PHA02562
endonuclease subunit; Provisional
 1833-2051 1.61e-03

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 43.46  E-value: 1.61e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1833 VRKLQQELELLS------QDKLALHSD--------SAQEQQQLQDKREALNSLQKELENTQDHLNLAKQDLMHTTKCQSA 1898
Cdd:PHA02562   176 IRELNQQIQTLDmkidhiQQQIKTYNKnieeqrkkNGENIARKQNKYDELVEEAKTIKAEIEELTDELLNLVMDIEDPSA 255

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1899 LLSEQAQLQKDVSqwtARLESCQKETE---------TKEQQLQELQDEIRESKLQLDQQEMVFQKLQKERESEEQKLVas 1969
Cdd:PHA02562   256 ALNKLNTAAAKIK---SKIEQFQKVIKmyekggvcpTCTQQISEGPDRITKIKDKLKELQHSLEKLDTAIDELEEIMD-- 330

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1970 ivsleqQQGQLERELMDQKSKLEWLLTDVSAAEGRLRTLQKEercTESLEKMLSQAKQQLSEREQQLMEKSGDLLALQKE 2049
Cdd:PHA02562   331 ------EFNEQSKKLLELKNKISTNKQSLITLVDKAKKVKAA---IEELQAEFVDNAEELAKLQDELDKIVKTKSELVKE 401


                   ..
gi 1958764989 2050 AD 2051
Cdd:PHA02562   402 KY 403
Crescentin pfam19220
Crescentin protein; This entry represents a bacterial equivalent to Intermediate Filament ...
 451-770 1.61e-03

Crescentin protein; This entry represents a bacterial equivalent to Intermediate Filament proteins, named crescentin, whose cytoskeletal function is required for the vibrioid and helical shapes of Caulobacter crescentus. Without crescentin, the cells adopt a straight-rod morphology. Crescentin has characteriztic features of IF proteins including the ability to assemble into filaments in vitro without energy or cofactor requirements. In vivo, crescentin forms a helical structure that colocalizes with the inner cell curvatures beneath the cytoplasmic membrane.


Pssm-ID: 437057 [Multi-domain]  Cd Length: 401  Bit Score: 43.13  E-value: 1.61e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  451 TRLSELHHEIEAAEQKVLRATQEFKQLEEAIRQKKISEAEKDLLLKQLSGRL----RHLNKLRQEALDLEAQLEKQRKEI 526
Cdd:pfam19220   76 RRLSAAEGELEELVARLAKLEAALREAEAAKEELRIELRDKTAQAEALERQLaaetEQNRALEEENKALREEAQAAEKAL 155

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  527 AEKHEEINSAQLATDLLDskdpkqshmkAQKRGKEQQLDIMNKQYTQLESRLDEILCRIATETEEIKDLEQQLTDGQIA- 605
Cdd:pfam19220  156 QRAEGELATARERLALLE----------QENRRLQALSEEQAAELAELTRRLAELETQLDATRARLRALEGQLAAEQAEr 225

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  606 ---------ANEALKKDLEGV---ISGLQEYLGTIKGQAAQAQNECRKLQDEKETLLQRLTEVKQEKDELEivamdaenm 673
Cdd:pfam19220  226 eraeaqleeAVEAHRAERASLrmkLEALTARAAATEQLLAEARNQLRDRDEAIRAAERRLKEASIERDTLE--------- 296

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  674 rKELAELENALQEQHEVNASLQQAQGDLSAYETELETQLKLKDAETSQLKQELENLvrRTQLEQsvLQTELEKERQSLRD 753
Cdd:pfam19220  297 -RRLAGLEADLERRTQQFQEMQRARAELEERAEMLTKALAAKDAALERAEERIASL--SDRIAE--LTKRFEVERAALEQ 371

                          330
                   ....*....|....*..
gi 1958764989  754 AlgKAQSSEEKQQENSE 770
Cdd:pfam19220  372 A--NRRLKEELQRERAE 386
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 260-682 1.69e-03

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 43.52  E-value: 1.69e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  260 RQEAFERFSLEEIERLEKDLEKKTVETEELKNKQTKFLEEIKH-QDKLNKSLKEEAMLQKQScEELESDLNTKKELLKQK 338
Cdd:TIGR02169  664 GGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDElSQELSDASRKIGEIEKEI-EQLEQEEEKLKERLEEL 742

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  339 TVELTRACQKQYELEQELAFY--KIDAKFEPLNYYPSEYAEMDKSPDESpyigksrykrnmfatetyivsdaqavQVRKM 416
Cdd:TIGR02169  743 EEDLSSLEQEIENVKSELKELeaRIEELEEDLHKLEEALNDLEARLSHS--------------------------RIPEI 796

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  417 VPDGGQLRHEHApraqappdvqleDTGKQIVAAQTRLSELHHEIEAAEQKVLRATQEFKQLEEairQKKISEAEKDLLLK 496
Cdd:TIGR02169  797 QAELSKLEEEVS------------RIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKE---QIKSIEKEIENLNG 861

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  497 QLSGRLRHLNKLRQEALDLEAQLEKQRKEIAEkheeinsaqlatdlldskdpkqshMKAQKRGKEQQLDIMNKQYTQLES 576
Cdd:TIGR02169  862 KKEELEEELEELEAALRDLESRLGDLKKERDE------------------------LEAQLRELERKIEELEAQIEKKRK 917

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  577 RLDEILCRIATETEEIKDLEQQLTDGQ-IAANEALKKDLEGVISGLQE---YLGTIKGQAAQ-------AQNECR----K 641
Cdd:TIGR02169  918 RLSELKAKLEALEEELSEIEDPKGEDEeIPEEELSLEDVQAELQRVEEeirALEPVNMLAIQeyeevlkRLDELKekraK 997

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|...
gi 1958764989  642 LQDEKETLLQRLTEVKQEKDELEIVAMDA--ENMRKELAELEN 682
Cdd:TIGR02169  998 LEEERKAILERIEEYEKKKREVFMEAFEAinENFNEIFAELSG 1040
46 PHA02562
endonuclease subunit; Provisional
 556-803 1.71e-03

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 43.46  E-value: 1.71e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  556 QKRGKEQQLDIMNKQYTQLESRLDEILCR-------IATETEEIKDLEQQLTDgQIAANEALKKDLEGVISGLQEYLGTI 628
Cdd:PHA02562   189 KIDHIQQQIKTYNKNIEEQRKKNGENIARkqnkydeLVEEAKTIKAEIEELTD-ELLNLVMDIEDPSAALNKLNTAAAKI 267

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  629 KGQAAQAQNECRKLQDEKE--TLLQ-------RLTEVKQEKDELEIVAMDAENMRKELAELENALQEQ----HEVNASLQ 695
Cdd:PHA02562   268 KSKIEQFQKVIKMYEKGGVcpTCTQqisegpdRITKIKDKLKELQHSLEKLDTAIDELEEIMDEFNEQskklLELKNKIS 347

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  696 QAQGDLSAYeteletqlklkDAETSQLKQELENLvrrtQLEQSVLQTELEKERQSLRDALGKAQSSEEKQQENSELRAQL 775
Cdd:PHA02562   348 TNKQSLITL-----------VDKAKKVKAAIEEL----QAEFVDNAEELAKLQDELDKIVKTKSELVKEKYHRGIVTDLL 412

                          250       260
                   ....*....|....*....|....*...
gi 1958764989  776 KQLQDDNSLLKKQLKDFQSHLNHVVDGL 803
Cdd:PHA02562   413 KDSGIKASIIKKYIPYFNKQINHYLQIM 440
mukB PRK04863
chromosome partition protein MukB;
1485-1992 1.79e-03

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 43.79  E-value: 1.79e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1485 RAQETALNLVK-AEQQLRLLQADAEDLEQHKIKQEEILKEINKVVAAKDADFQCLNEKKEKLTEELQSLQRdIKAAEVNE 1563
Cdd:PRK04863   530 RQQQRAERLLAeFCKRLGKNLDDEDELEQLQEELEARLESLSESVSEARERRMALRQQLEQLQARIQRLAA-RAPAWLAA 608

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1564 DHHLQVLKESESLLQAKRAELETLKSQVTSQQQELAVLDSQLGHRREELLLLQDSLTQAK-ADLQEALTLGETEVAEKCS 1642
Cdd:PRK04863   609 QDALARLREQSGEEFEDSQDVTEYMQQLLERERELTVERDELAARKQALDEEIERLSQPGgSEDPRLNALAERFGGVLLS 688

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1643 HIREVKSLLE--ELSFQKGELNVHI-----SERRTQL------------------TLIKQEIEKEEENLEVVLQ------ 1691
Cdd:PRK04863   689 EIYDDVSLEDapYFSALYGPARHAIvvpdlSDAAEQLagledcpedlyliegdpdSFDDSVFSVEELEKAVVVKiadrqw 768

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1692 QLSKHKTE-------LKNVADILQLETNELQSlklQHDQKVVELEKTQ------VDLLEGKLEL------ESLQQTAQQQ 1752
Cdd:PRK04863   769 RYSRFPEVplfgraaREKRIEQLRAEREELAE---RYATLSFDVQKLQrlhqafSRFIGSHLAVafeadpEAELRQLNRR 845

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1753 RRELERQrqlLERDRRETERVRAETQALQSCIECLNKEKEHLQEQCEswekkSSHAKRVLAATEESNNTEQSK------- 1825
Cdd:PRK04863   846 RVELERA---LADHESQEQQQRSQLEQAKEGLSALNRLLPRLNLLAD-----ETLADRVEEIREQLDEAEEAKrfvqqhg 917

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1826 --LGQLEVSVRKLQ---QELELLSQDklalHSDSAQEQQQLQDKREALNSL------------QKELENTQDHLNLAKQD 1888
Cdd:PRK04863   918 naLAQLEPIVSVLQsdpEQFEQLKQD----YQQAQQTQRDAKQQAFALTEVvqrrahfsyedaAEMLAKNSDLNEKLRQR 993

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1889 LMHTTKCQSALLSEQAQLQKDVSQWTARLESCQKETETKEQQLQELQDEIRESKLQLDQQEMvfQKLQKERESEEQKLVA 1968
Cdd:PRK04863   994 LEQAEQERTRAREQLRQAQAQLAQYNQVLASLKSSYDAKRQMLQELKQELQDLGVPADSGAE--ERARARRDELHARLSA 1071

                          570       580
                   ....*....|....*....|....*..
gi 1958764989 1969 S---IVSLEQQQGQLERELMDQKSKLE 1992
Cdd:PRK04863  1072 NrsrRNQLEKQLTFCEAEMDNLTKKLR 1098
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1327-1729 1.88e-03

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 43.57  E-value: 1.88e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1327 VSRLEDITHHLKSKHQEERWLKTSRQHPEKEVEELHRNIDDLVQEKKELELEVEELHRTVERHQQRRDFIDGNVENLMTE 1406
Cdd:pfam15921  460 LEKVSSLTAQLESTKEMLRKVVEELTAKKMTLESSERTVSDLTASLQEKERAIEATNAEITKLRSRVDLKLQELQHLKNE 539

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1407 LEiekslkHHEDIVDEIECLeKTLLKRRSELREADRLLAEAESELACTKEKTKSAVEkftdAKRNLLQTESDAEALEkrA 1486
Cdd:pfam15921  540 GD------HLRNVQTECEAL-KLQMAEKDKVIEILRQQIENMTQLVGQHGRTAGAMQ----VEKAQLEKEINDRRLE--L 606

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1487 QETALNLVKAEQQLRLLQADAEDLEQHKIK----QEEILKEINKVVAAKDadfQCLNEKK------EKLTEELQSLQRDI 1556
Cdd:pfam15921  607 QEFKILKDKKDAKIRELEARVSDLELEKVKlvnaGSERLRAVKDIKQERD---QLLNEVKtsrnelNSLSEDYEVLKRNF 683

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1557 K----AAEVNEDHHLQVLKESESLLQAKRAELETLKSQVTSQQQELAVLDSQLGHRREELlllqDSLTQAKADLQEALTL 1632
Cdd:pfam15921  684 RnkseEMETTTNKLKMQLKSAQSELEQTRNTLKSMEGSDGHAMKVAMGMQKQITAKRGQI----DALQSKIQFLEEAMTN 759

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1633 GETEV----AEKCSHIREVKSLLEELSFQKGELNVHISERRtqltlikqEIEKEEENLEVVLQQLSKHKTELKnvaDILQ 1708
Cdd:pfam15921  760 ANKEKhflkEEKNKLSQELSTVATEKNKMAGELEVLRSQER--------RLKEKVANMEVALDKASLQFAECQ---DIIQ 828

                          410       420
                   ....*....|....*....|.
gi 1958764989 1709 LETNELQSLKLQHDQKVVELE 1729
Cdd:pfam15921  829 RQEQESVRLKLQHTLDVKELQ 849
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1355-1886 1.89e-03

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 43.47  E-value: 1.89e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1355 EKEVEELHRNIDDLVQEKKELELEVEELHRTVERHQQRRDFIDGNVENLMTEL-EIEKSLKHHEDIVDEIECLEKTLLKR 1433
Cdd:TIGR04523  151 EKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNIDKIKNKLLKLELLLsNLKKKIQKNKSLESQISELKKQNNQL 230

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1434 RSELREADRLLAEAESELACTKEKTKSAVEKFTDAKRNLLQTESDAEALEKRAQETalnlvkaEQQLRLLQADAEDLEQH 1513
Cdd:TIGR04523  231 KDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKELEQNNKKIKEL-------EKQLNQLKSEISDLNNQ 303

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1514 kiKQEEILKEINKVVAAKDADFQCLNEKKEKLTEELQSLQRDIKAAEVNEDHHLQVLKESESLLQAKRAELETLKSQVTS 1593
Cdd:TIGR04523  304 --KEQDWNKELKSELKNQEKKLEEIQNQISQNNKIISQLNEQISQLKKELTNSESENSEKQRELEEKQNEIEKLKKENQS 381

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1594 QQQELAVLDSQLGHRREELlllqDSLTQAKADLQEALTLGETEVAEKCSHIREVKSLLEELSFQKGELNVHISERRTQLT 1673
Cdd:TIGR04523  382 YKQEIKNLESQINDLESKI----QNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIK 457

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1674 LIKQEIEKEEENLEVVLQQLSKHKTELKNVADILQLETNELQSLKLQH---DQKVVELEKTQVDLLEGKLELESLQQTAQ 1750
Cdd:TIGR04523  458 NLDNTRESLETQLKVLSRSINKIKQNLEQKQKELKSKEKELKKLNEEKkelEEKVKDLTKKISSLKEKIEKLESEKKEKE 537

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1751 QQRRELERQrqlLERDRRETERVRAETQalqscIECLNKEKEHLQEQCESWEKKSSHAKRVLAATEESNNTEQSKLGQLE 1830
Cdd:TIGR04523  538 SKISDLEDE---LNKDDFELKKENLEKE-----IDEKNKEIEELKQTQKSLKKKQEEKQELIDQKEKEKKDLIKEIEEKE 609

                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1958764989 1831 VSVRKLQQELELLSQDKLALHSdsaqeqqQLQDKREALNSLQKELENTQDHLNLAK 1886
Cdd:TIGR04523  610 KKISSLEKELEKAKKENEKLSS-------IIKNIKSKKNKLKQEVKQIKETIKEIR 658
DUF3450 pfam11932
Protein of unknown function (DUF3450); This family of proteins are functionally ...
 631-761 2.05e-03

Protein of unknown function (DUF3450); This family of proteins are functionally uncharacterized. This protein is found in bacteria and eukaryotes. Proteins in this family are about 260 amino acids in length.


Pssm-ID: 432198 [Multi-domain]  Cd Length: 238  Bit Score: 42.22  E-value: 2.05e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  631 QAAQAQNECRKLQDEKETLLQRLTEVKQEKdeleivamdaENMRKELAELENALQEQHEVNASLQQAQGDLSAYETELET 710
Cdd:pfam11932   28 AAAQSQKKIDKWDDEKQELLAEYRALKAEL----------ESLEVYNRQLERLVASQEQEIASLERQIEEIERTERELVP 97

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1958764989  711 QLklkDAETSQLKQELENLVrrtqleqSVLQTELEKERQSLRDALGKAQSS 761
Cdd:pfam11932   98 LM---LKMLDRLEQFVALDL-------PFLLEERQARLARLRELMDDADVS 138
mukB PRK04863
chromosome partition protein MukB;
1434-1838 2.13e-03

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 43.41  E-value: 2.13e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1434 RSELREADRLLAEAESELACTKEKTKSAVEKFTDAKRNLLQTESDAEALEKRAQETA--LNLVKA----EQQLRLLQADA 1507
Cdd:PRK04863   278 ANERRVHLEEALELRRELYTSRRQLAAEQYRLVEMARELAELNEAESDLEQDYQAASdhLNLVQTalrqQEKIERYQADL 357

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1508 EDLEQHKIKQEEILKEINKVVAAKDADFQCLNEKKEKLTEELQSLQRDIKAAE---VNEDHHLQVLKESESLLQAKRAEL 1584
Cdd:PRK04863   358 EELEERLEEQNEVVEEADEQQEENEARAEAAEEEVDELKSQLADYQQALDVQQtraIQYQQAVQALERAKQLCGLPDLTA 437

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1585 ETLKSQVTSQQQELAVLDSQLGHRREELLLLQDSLTQAKADLQEALTLGEtEVAEKCSHiREVKSLLEELSFQKgelnvH 1664
Cdd:PRK04863   438 DNAEDWLEEFQAKEQEATEELLSLEQKLSVAQAAHSQFEQAYQLVRKIAG-EVSRSEAW-DVARELLRRLREQR-----H 510

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1665 ISERRTQLTlikqeiekeeenlevvlQQLSKHKTELKNVADILQLETNELQSLKLQHDQkVVELEKTQVDLLEGKLELES 1744
Cdd:PRK04863   511 LAEQLQQLR-----------------MRLSELEQRLRQQQRAERLLAEFCKRLGKNLDD-EDELEQLQEELEARLESLSE 572

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1745 LQQTAQQQRRELERQRQLLERDRRETERVRAETQALQSCIeclnkekEHLQEQCESWEKKS--------SHAKRVLAATE 1816
Cdd:PRK04863   573 SVSEARERRMALRQQLEQLQARIQRLAARAPAWLAAQDAL-------ARLREQSGEEFEDSqdvteymqQLLERERELTV 645

                          410       420
                   ....*....|....*....|..
gi 1958764989 1817 ESNNTEQSKlGQLEVSVRKLQQ 1838
Cdd:PRK04863   646 ERDELAARK-QALDEEIERLSQ 666
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 1964-2111 2.19e-03

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 41.83  E-value: 2.19e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1964 QKLVASIVSLEQQQGQLERELMDQKSKLEWLLTDVSAAEGRLRTLQKEERcteSLEKMLSQAKQQLSEREQQLMEKSG-- 2041
Cdd:COG1579     13 QELDSELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIK---RLELEIEEVEARIKKYEEQLGNVRNnk 89

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1958764989 2042 DLLALQKEADGMRADFSLLRNQ---FLTERKKAEKQVAGLKEALKIQRSQLEKNLLEQKQENSCMQKEMATIE 2111
Cdd:COG1579     90 EYEALQKEIESLKRRISDLEDEileLMERIEELEEELAELEAELAELEAELEEKKAELDEELAELEAELEELE 162
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 651-1056 2.31e-03

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 43.24  E-value: 2.31e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  651 QRLTEVKQEKDELEIVAMDAENMRKELAELENALQEQhevnaslQQAQGDLSAYETELETQLKLKDAETSQLKQELENLV 730
Cdd:pfam01576   12 EELQKVKERQQKAESELKELEKKHQQLCEEKNALQEQ-------LQAETELCAEAEEMRARLAARKQELEEILHELESRL 84

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  731 RRTQLEQSVLQTELEKERQSLRDALGKAQSSEEKQQ----ENSELRAQLKQLQDD-------NSLLKKQLKDFQSHLNHV 799
Cdd:pfam01576   85 EEEEERSQQLQNEKKKMQQHIQDLEEQLDEEEAARQklqlEKVTTEAKIKKLEEDillledqNSKLSKERKLLEERISEF 164

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  800 VDGLIHPEEVAARVDELRK-------------------RLKLGAGEMRIHSPSDVLGKSLADLQKQFSEILARSQWEKEE 860
Cdd:pfam01576  165 TSNLAEEEEKAKSLSKLKNkheamisdleerlkkeekgRQELEKAKRKLEGESTDLQEQIAELQAQIAELRAQLAKKEEE 244

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  861 AQVRERKLHEEMALQQEKLANGQE------EFKQACERALEARIKFDKRQHNARiQQLENEIHYLQENLKSMEKIQGLTD 934
Cdd:pfam01576  245 LQAALARLEEETAQKNNALKKIREleaqisELQEDLESERAARNKAEKQRRDLG-EELEALKTELEDTLDTTAAQQELRS 323

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  935 LQLQEA-------DEEKERILAQLQELEKKKRREDARSQEQFLGLDTELKSLKKAVAASDKlaaaELTIAKEQLKSLHGT 1007
Cdd:pfam01576  324 KREQEVtelkkalEEETRSHEAQLQEMRQKHTQALEELTEQLEQAKRNKANLEKAKQALES----ENAELQAELRTLQQA 399

                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1958764989 1008 VMRINQERAE---ELQE----AERSSREAMQAAKDLSRAEAEIELLQHLLREREGQ 1056
Cdd:pfam01576  400 KQDSEHKRKKlegQLQElqarLSESERQRAELAEKLSKLQSELESVSSLLNEAEGK 455
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 735-1141 2.36e-03

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 43.18  E-value: 2.36e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  735 LEQSV--LQTELEkERQSLRDALGKAQSSEEKQQEN--SELRAQLKQLQDDNSLLKKQLKDFQSHLNHVVDGLIHPEEVA 810
Cdd:pfam15921  108 LRQSVidLQTKLQ-EMQMERDAMADIRRRESQSQEDlrNQLQNTVHELEAAKCLKEDMLEDSNTQIEQLRKMMLSHEGVL 186

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  811 ARVDELRKRLKLGAGEmRIHSPSDVLGKSLADLQKQFSEILarsqwekeeaqvreRKLHEEMALQQEKLANGQEEFkQAC 890
Cdd:pfam15921  187 QEIRSILVDFEEASGK-KIYEHDSMSTMHFRSLGSAISKIL--------------RELDTEISYLKGRIFPVEDQL-EAL 250

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  891 ERALEARIKFDKRQHNARIQQLENEiHYLQenlksmekIQGLTDlQLQEADEEKERILAQLQELEKKKRREDARSQEQFL 970
Cdd:pfam15921  251 KSESQNKIELLLQQHQDRIEQLISE-HEVE--------ITGLTE-KASSARSQANSIQSQLEIIQEQARNQNSMYMRQLS 320

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  971 GLDTELKSLKKAVAASDKLAAAELTIAKEQLKSLHGTVMRINQERAEELQEAERSSREAMQAAKDLSRAEAEIELLQHL- 1049
Cdd:pfam15921  321 DLESTVSQLRSELREAKRMYEDKIEELEKQLVLANSELTEARTERDQFSQESGNLDDQLQKLLADLHKREKELSLEKEQn 400

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1050 --LREREGQFRDEMENAHVGSKGANLQLLEIEALKEA--------MAKQRAEIT----RLRDVLNLTGT--GKKGGIENV 1113
Cdd:pfam15921  401 krLWDRDTGNSITIDHLRRELDDRNMEVQRLEALLKAmksecqgqMERQMAAIQgkneSLEKVSSLTAQleSTKEMLRKV 480

                          410       420
                   ....*....|....*....|....*...
gi 1958764989 1114 VEEIAELRHAVSAQNEYISSMADPVQRQ 1141
Cdd:pfam15921  481 VEELTAKKMTLESSERTVSDLTASLQEK 508
PRK01156 PRK01156
chromosome segregation protein; Provisional
 266-821 2.41e-03

chromosome segregation protein; Provisional


Pssm-ID: 100796 [Multi-domain]  Cd Length: 895  Bit Score: 42.97  E-value: 2.41e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  266 RFSLEEIERLEKDLEKKTVETEELKNKQTKflEEIKHQDKLNKslKEEAMLQKQSCEElesDLNTKKELLKQKTVELTRA 345
Cdd:PRK01156   179 RAEISNIDYLEEKLKSSNLELENIKKQIAD--DEKSHSITLKE--IERLSIEYNNAMD---DYNNLKSALNELSSLEDMK 251

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  346 cqKQYELEQELAFYKIDAKFEPLNYYPSEYAEMDKSPDESPYIGKSRYKrnmfateTYIVSDAQAVQVRKMVPD-GGQLR 424
Cdd:PRK01156   252 --NRYESEIKTAESDLSMELEKNNYYKELEERHMKIINDPVYKNRNYIN-------DYFKYKNDIENKKQILSNiDAEIN 322

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  425 HEHAPRAQAPpdvQLEDTGKQIVAAQTRLSELHHEIEAAEQKVLRATQEFKQLEEaiRQKKISEAEKDLllKQLSGRL-R 503
Cdd:PRK01156   323 KYHAIIKKLS---VLQKDYNDYIKKKSRYDDLNNQILELEGYEMDYNSYLKSIES--LKKKIEEYSKNI--ERMSAFIsE 395

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  504 HLNKLRQEALDLEAQLEKQRKEIAEKHEEINSAQLATDLLDSKDPKQSHMKAQKRGK-----------EQQLDIMNKQYT 572
Cdd:PRK01156   396 ILKIQEIDPDAIKKELNEINVKLQDISSKVSSLNQRIRALRENLDELSRNMEMLNGQsvcpvcgttlgEEKSNHIINHYN 475

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  573 QLESRLDEilcRIATETEEIKDLEQQLTDgqiaaneaLKKDLEGVISGLQEYLGTIKGQAAQAQNECRKLQDEKETLLQR 652
Cdd:PRK01156   476 EKKSRLEE---KIREIEIEVKDIDEKIVD--------LKKRKEYLESEEINKSINEYNKIESARADLEDIKIKINELKDK 544

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  653 ltEVKQEKDELEIVAMDAENMRKELAELENAL------------QEQHEVNASLQQAQGDLSAYETELETQLKLKDAETS 720
Cdd:PRK01156   545 --HDKYEEIKNRYKSLKLEDLDSKRTSWLNALavislidietnrSRSNEIKKQLNDLESRLQEIEIGFPDDKSYIDKSIR 622

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  721 QLKQELENLVRRTQLEQSvLQTELEKERQSLRDALGKAQSSEEKQQENSELRAQLKQLQDDNSLLKKQLKDFQSHLNH-- 798
Cdd:PRK01156   623 EIENEANNLNNKYNEIQE-NKILIEKLRGKIDNYKKQIAEIDSIIPDLKEITSRINDIEDNLKKSRKALDDAKANRARle 701

                          570       580
                   ....*....|....*....|....*
gi 1958764989  799 --VVDGLIHPEEVAARVDELRKRLK 821
Cdd:PRK01156   702 stIEILRTRINELSDRINDINETLE 726
PRK11637 PRK11637
AmiB activator; Provisional
 505-785 2.43e-03

AmiB activator; Provisional


Pssm-ID: 236942 [Multi-domain]  Cd Length: 428  Bit Score: 42.76  E-value: 2.43e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  505 LNKLRQEALDLEAQLEKQRKEIAEKHEEINSAQlatdlldskdPKQSHMKAQKRGKEQQLDIMNKQYTQLESRLDEILCR 584
Cdd:PRK11637    35 LCAFSAHASDNRDQLKSIQQDIAAKEKSVRQQQ----------QQRASLLAQLKKQEEAISQASRKLRETQNTLNQLNKQ 104

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  585 IATETEEIKDLEQQltdgQIAANEALKKDL-----EGVISGLQEYLGTIKGQAAQA-------QNECRklQDEKETLLQR 652
Cdd:PRK11637   105 IDELNASIAKLEQQ----QAAQERLLAAQLdaafrQGEHTGLQLILSGEESQRGERilayfgyLNQAR--QETIAELKQT 178

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  653 LTEVKQEKDELEivamDAENMRKELaelenaLQEQHEVNASLQQAQGDLSAYETELETQLKLKDAETSQLKQElenlvrR 732
Cdd:PRK11637   179 REELAAQKAELE----EKQSQQKTL------LYEQQAQQQKLEQARNERKKTLTGLESSLQKDQQQLSELRAN------E 242

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1958764989  733 TQLEQSVLQTELEKERQSLRDALgKAQSSEEKQQENSELRAQLKQLQDDNSLL 785
Cdd:PRK11637   243 SRLRDSIARAEREAKARAEREAR-EAARVRDKQKQAKRKGSTYKPTESERSLM 294
mukB PRK04863
chromosome partition protein MukB;
1752-2091 2.70e-03

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 43.02  E-value: 2.70e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1752 QRRELERQRQLLERDRRETERVRAETQ----ALQSCIECLNKEKEHLQEQCESwekKSSHAKRVLAATEEsnnteQSKLG 1827
Cdd:PRK04863   280 ERRVHLEEALELRRELYTSRRQLAAEQyrlvEMARELAELNEAESDLEQDYQA---ASDHLNLVQTALRQ-----QEKIE 351

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1828 QLEVSVRKLQQELELLSQDKLALHSDSAQEQQQLQDKREALNSLQKELENTQDHLNLAKQDLMHTTKCQSALLSEQAQLQ 1907
Cdd:PRK04863   352 RYQADLEELEERLEEQNEVVEEADEQQEENEARAEAAEEEVDELKSQLADYQQALDVQQTRAIQYQQAVQALERAKQLCG 431

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1908 KD---VSQWTARLESCQKETETKEQQLQELQDEIRESKLQLDQQEMVFQKLQKereseeqkLVASIVSLEQQQgqLEREL 1984
Cdd:PRK04863   432 LPdltADNAEDWLEEFQAKEQEATEELLSLEQKLSVAQAAHSQFEQAYQLVRK--------IAGEVSRSEAWD--VAREL 501

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1985 MDQKSKLEWLLTDVSAAEGRLRTLQKEERCTESLEKMLSQAKQQLSereqQLMEKSGDLLALQKEADGMRADFSLLRNQf 2064
Cdd:PRK04863   502 LRRLREQRHLAEQLQQLRMRLSELEQRLRQQQRAERLLAEFCKRLG----KNLDDEDELEQLQEELEARLESLSESVSE- 576

                          330       340
                   ....*....|....*....|....*..
gi 1958764989 2065 LTERKKAEKQVaglKEALKIQRSQLEK 2091
Cdd:PRK04863   577 ARERRMALRQQ---LEQLQARIQRLAA 600
COG5022 COG5022
Myosin heavy chain [General function prediction only];
1384-1984 2.88e-03

Myosin heavy chain [General function prediction only];


Pssm-ID: 227355 [Multi-domain]  Cd Length: 1463  Bit Score: 43.14  E-value: 2.88e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1384 RTVERHQQRRDFIDGNV--ENLMTELEIEKSLKHHEDIVDEIECLEKTLLKRRSELREADRLLAEAESElactkeKTKSA 1461
Cdd:COG5022    853 RSLKAKKRFSLLKKETIylQSAQRVELAERQLQELKIDVKSISSLKLVNLELESEIIELKKSLSSDLIE------NLEFK 926

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1462 VEKFTDAKRNLLQTESDAEAL-EKRAQETALNLVKAEQQLRLLQADAED-LEQHKIKQEEILKEINKVVAAKD--ADFQC 1537
Cdd:COG5022    927 TELIARLKKLLNNIDLEEGPSiEYVKLPELNKLHEVESKLKETSEEYEDlLKKSTILVREGNKANSELKNFKKelAELSK 1006

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1538 LNEKKEKLTEELQSLQRdikaaEVNEDHHLQVLKESESLLQAKRAELETLKSQVTSQQQELAVLDSQLGHRREELLLLQD 1617
Cdd:COG5022   1007 QYGALQESTKQLKELPV-----EVAELQSASKIISSESTELSILKPLQKLKGLLLLENNQLQARYKALKLRRENSLLDDK 1081

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1618 SLTQAKAdlqealtlgeTEVAEKCSHIREVKSLLEELSFQKGELNVHISErrtQLTLIKQEIEKEEENLEVVLQQLSKHK 1697
Cdd:COG5022   1082 QLYQLES----------TENLLKTINVKDLEVTNRNLVKPANVLQFIVAQ---MIKLNLLQEISKFLSQLVNTLEPVFQK 1148

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1698 TELKN-VADILQLETNELQSLKLQHDQKVVELEKTQVDLLEGKLELESLQQTaqqqrrELERQRQLLERDRRETERVRAE 1776
Cdd:COG5022   1149 LSVLQlELDGLFWEANLEALPSPPPFAALSEKRLYQSALYDEKSKLSSSEVN------DLKNELIALFSKIFSGWPRGDK 1222

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1777 TQALQSCIECLNKEKEHLQEQCESWEKKSSHAKR----VLAATEESNNTEQSKLGQLEVSVRKLQQEL--------ELLS 1844
Cdd:COG5022   1223 LKKLISEGWVPTEYSTSLKGFNNLNKKFDTPASMsnekLLSLLNSIDNLLSSYKLEEEVLPATINSLLqyinvglfNALR 1302

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1845 QDKLALHSDSAQEQQQLQD------KREALNSLQKELEN---TQDHLNLAKQDLMHTTKCQSALlseQAQLQKDVSQWTA 1915
Cdd:COG5022   1303 TKASSLRWKSATEVNYNSEelddwcREFEISDVDEELEEliqAVKVLQLLKDDLNKLDELLDAC---YSLNPAEIQNLKS 1379

                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1958764989 1916 RLESCQKETETKEQQLQELQDEIRESKLQLdqQEMVFQKLQKEReSEEQKLVASIVSLEQQQGQLEREL 1984
Cdd:COG5022   1380 RYDPADKENNLPKEILKKIEALLIKQELQL--SLEGKDETEVHL-SEIFSEEKSLISLDRNSIYKEEVL 1445
mukB PRK04863
chromosome partition protein MukB;
631-987 2.91e-03

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 43.02  E-value: 2.91e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  631 QAAQAQNECRKLQDEKETLLQRLTEVKQEKDELE----IVAMDAENMRKELAELENALQEQHEvnasLQQAQGDLSAYET 706
Cdd:PRK04863   287 EALELRRELYTSRRQLAAEQYRLVEMARELAELNeaesDLEQDYQAASDHLNLVQTALRQQEK----IERYQADLEELEE 362

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  707 ELETQLKLKdAETSQLKQELENLVRRTQLEQSVLQTELEKERQslrdALGKAQSSEEKQQENSELRAQLKQLQDDNSLLK 786
Cdd:PRK04863   363 RLEEQNEVV-EEADEQQEENEARAEAAEEEVDELKSQLADYQQ----ALDVQQTRAIQYQQAVQALERAKQLCGLPDLTA 437

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  787 KQLKDFQSHLNHvvdgliHPEEVAARVDELRKRLKLGAGEMRIHSPSDVLGKSLA------DLQKQFSEILARSQWEKEE 860
Cdd:PRK04863   438 DNAEDWLEEFQA------KEQEATEELLSLEQKLSVAQAAHSQFEQAYQLVRKIAgevsrsEAWDVARELLRRLREQRHL 511

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  861 A---QVRERKLHE-EMALQQEKLANGQ-EEFKQACERALEARIKFDK--RQHNARIQQLE----------NEIHYLQENL 923
Cdd:PRK04863   512 AeqlQQLRMRLSElEQRLRQQQRAERLlAEFCKRLGKNLDDEDELEQlqEELEARLESLSesvsearerrMALRQQLEQL 591

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  924 KSmeKIQGLTDL------------QLQE----ADEEKERI---LAQLQELEKKKRREDARSQEQFLGLDTELKSLKKAVA 984
Cdd:PRK04863   592 QA--RIQRLAARapawlaaqdalaRLREqsgeEFEDSQDVteyMQQLLERERELTVERDELAARKQALDEEIERLSQPGG 669


                   ...
gi 1958764989  985 ASD 987
Cdd:PRK04863   670 SED 672
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 560-988 2.97e-03

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 42.85  E-value: 2.97e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  560 KEQQLDIMNKQYTQLESRLDEILCRIATETEEIKDLEQQLTDGQIAANEA---------LKKDLEGVISGLQEYLGTIKG 630
Cdd:pfam01576   10 KEEELQKVKERQQKAESELKELEKKHQQLCEEKNALQEQLQAETELCAEAeemrarlaaRKQELEEILHELESRLEEEEE 89

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  631 QAAQAQNECRKLQ----------DEKETLLQRL------TEVKQEKDELEIVAMDAEN---------MRKELAELENALQ 685
Cdd:pfam01576   90 RSQQLQNEKKKMQqhiqdleeqlDEEEAARQKLqlekvtTEAKIKKLEEDILLLEDQNsklskerklLEERISEFTSNLA 169

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  686 EQHEVNASLQQAQGDLSAYETELETQLKlkdaETSQLKQELENLVRRTQLEQSVLQTELEKERQSLRDALGKAQSSEEKQ 765
Cdd:pfam01576  170 EEEEKAKSLSKLKNKHEAMISDLEERLK----KEEKGRQELEKAKRKLEGESTDLQEQIAELQAQIAELRAQLAKKEEEL 245

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  766 QensELRAQLKQLQDDNSLLKKQLKDFQSHLNHVVDGLihPEEVAARVDELRKRLKLGagemrihSPSDVLGKSLAD-LQ 844
Cdd:pfam01576  246 Q---AALARLEEETAQKNNALKKIRELEAQISELQEDL--ESERAARNKAEKQRRDLG-------EELEALKTELEDtLD 313

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  845 KQFSEILARSQWEKEEAQVR-----ERKLHE-EMALQQEKLANGQEEFKQACERALEARIKFDKRQhnariQQLENEIHY 918
Cdd:pfam01576  314 TTAAQQELRSKREQEVTELKkaleeETRSHEaQLQEMRQKHTQALEELTEQLEQAKRNKANLEKAK-----QALESENAE 388

                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1958764989  919 LQENLKSMEKIQgltdlqlQEADEEKERILAQLQELEKK---KRREDARSQEQFLGLDTELKSLKKAVAASDK 988
Cdd:pfam01576  389 LQAELRTLQQAK-------QDSEHKRKKLEGQLQELQARlseSERQRAELAEKLSKLQSELESVSSLLNEAEG 454
PRK11281 PRK11281
mechanosensitive channel MscK;
1751-2029 2.98e-03

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 42.98  E-value: 2.98e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1751 QQRRELERQRQLLERDRRETERVRAETQALQSCIECLNKEKEHLQEQCESWEKKSSHAKRVLAATEESNNTEQSK----- 1825
Cdd:PRK11281    42 QAQLDALNKQKLLEAEDKLVQQDLEQTLALLDKIDRQKEETEQLKQQLAQAPAKLRQAQAELEALKDDNDEETREtlstl 121

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1826 -LGQLEVSVRKLQQELELLSQDKLALHSD--SAQEQ------------QQLQDKREALNSL---QKELENTQDHLNLAKQ 1887
Cdd:PRK11281   122 sLRQLESRLAQTLDQLQNAQNDLAEYNSQlvSLQTQperaqaalyansQRLQQIRNLLKGGkvgGKALRPSQRVLLQAEQ 201

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1888 DLMhttkcqSALLSEQAQLQKDVSQWTARLESCQKETETK----EQQLQELQDEIRESKLQLDQQEMV-FQKLQKERESE 1962
Cdd:PRK11281   202 ALL------NAQNDLQRKSLEGNTQLQDLLQKQRDYLTARiqrlEHQLQLLQEAINSKRLTLSEKTVQeAQSQDEAARIQ 275

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1958764989 1963 EQKLVASIVSLEQqqgQLERELMDQKSKLEWLLTDVSAAEGRLRTLQKEERCTES----------LEKMLSQAKQQL 2029
Cdd:PRK11281   276 ANPLVAQELEINL---QLSQRLLKATEKLNTLTQQNLRVKNWLDRLTQSERNIKEqisvlkgsllLSRILYQQQQAL 349
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 1573-1948 3.02e-03

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 43.02  E-value: 3.02e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1573 SESLLQAkRAELETLKSQVTSQQQELAVLDSQLghrrEELLLLQDSLTQakaDLQEA---LTLGETEV--AEKCSHIRE- 1646
Cdd:COG3096    284 SERALEL-RRELFGARRQLAEEQYRLVEMAREL----EELSARESDLEQ---DYQAAsdhLNLVQTALrqQEKIERYQEd 355

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1647 VKSL---LEELSFQKGELNVHISERRTQLTLIKqeiekeeenlevvlQQLSKHKTELknvADiLQLETNELQSLKLQHDQ 1723
Cdd:COG3096    356 LEELterLEEQEEVVEEAAEQLAEAEARLEAAE--------------EEVDSLKSQL---AD-YQQALDVQQTRAIQYQQ 417

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1724 KVVELEKTQVDLLEGKLELESL----------QQTAQQQRRELERQRQLLERDRRETERVraeTQALQSCIECLNKEKEH 1793
Cdd:COG3096    418 AVQALEKARALCGLPDLTPENAedylaafrakEQQATEEVLELEQKLSVADAARRQFEKA---YELVCKIAGEVERSQAW 494

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1794 --LQEQCESWEKKSSHAKRVLAATEESNNTEQsKLGQLEvSVRKLQQELELLSQDKLALHSDSAQEQQQLQDKREAL--- 1868
Cdd:COG3096    495 qtARELLRRYRSQQALAQRLQQLRAQLAELEQ-RLRQQQ-NAERLLEEFCQRIGQQLDAAEELEELLAELEAQLEELeeq 572

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1869 -NSLQKELENTQDHLNLAKQDLMHTTKCQSALLSEQAQLQKDVSQWTARLESCQKETETKEQQLQEL------QDEIRES 1941
Cdd:COG3096    573 aAEAVEQRSELRQQLEQLRARIKELAARAPAWLAAQDALERLREQSGEALADSQEVTAAMQQLLEREreatveRDELAAR 652


                   ....*..
gi 1958764989 1942 KLQLDQQ 1948
Cdd:COG3096    653 KQALESQ 659
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1791-2130 3.59e-03

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 42.80  E-value: 3.59e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1791 KEHLQEQCESWEKKSSHAKRVLaatEESNNTEQSKLGQLEVSVRKLQQELELLSQDKLALHSDSAQEQQQLQDKREALNS 1870
Cdd:pfam15921   73 KEHIERVLEEYSHQVKDLQRRL---NESNELHEKQKFYLRQSVIDLQTKLQEMQMERDAMADIRRRESQSQEDLRNQLQN 149

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1871 LQKELENTQdhlnLAKQDLMHTTKCQ-----SALLSEQAQLQKDVSQWTARLESCQKETETKE---------------QQ 1930
Cdd:pfam15921  150 TVHELEAAK----CLKEDMLEDSNTQieqlrKMMLSHEGVLQEIRSILVDFEEASGKKIYEHDsmstmhfrslgsaisKI 225

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1931 LQELQDEIRESKLQLDQQEMVFQKLQKERESEEQKLvasivsLEQQQGQLERELMDQKSKLEWLLTDVSAAEGRLRTLQK 2010
Cdd:pfam15921  226 LRELDTEISYLKGRIFPVEDQLEALKSESQNKIELL------LQQHQDRIEQLISEHEVEITGLTEKASSARSQANSIQS 299

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 2011 EerctesLEKMLSQAKQQLSEREQQLMEksgdllalqkeadgMRADFSLLRNQFLTERKKAEKQVAGLKEALKIQRSQLE 2090
Cdd:pfam15921  300 Q------LEIIQEQARNQNSMYMRQLSD--------------LESTVSQLRSELREAKRMYEDKIEELEKQLVLANSELT 359

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|
gi 1958764989 2091 KNLLEQKQENSCMQKEMATIELVAQDNHERARRLMKELRQ 2130
Cdd:pfam15921  360 EARTERDQFSQESGNLDDQLQKLLADLHKREKELSLEKEQ 399
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1350-1560 3.86e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 42.06  E-value: 3.86e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1350 SRQHPEKEVEELHRNIDDLVQEKKELELEVEELHRTVERHQQRRDFIDGNVENLMTEL-EIEKSLKhheDIVDEIECLEK 1428
Cdd:COG4942     21 AAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELaALEAELA---ELEKEIAELRA 97

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1429 TLLKRRSELREadrLLAEAESELACTKEKTKSAVEKFTDAKRNLLQTESDAEALEKRAQETALNLVKAEQQLRLLQADAE 1508
Cdd:COG4942     98 ELEAQKEELAE---LLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERA 174

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|..
gi 1958764989 1509 DLEQHKIKQEEILKEINKVVAAKDADFQCLNEKKEKLTEELQSLQRDIKAAE 1560
Cdd:COG4942    175 ELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELE 226
mukB PRK04863
chromosome partition protein MukB;
1581-1948 3.87e-03

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 42.64  E-value: 3.87e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1581 RAELETLKSQVTSQQQELAVLDSQLGHRREELLLLQDSLTQAKADLQEALT-LGETEVAEKCShirevkSLLEELSFQKG 1659
Cdd:PRK04863   292 RRELYTSRRQLAAEQYRLVEMARELAELNEAESDLEQDYQAASDHLNLVQTaLRQQEKIERYQ------ADLEELEERLE 365

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1660 ELNVHISERRTQLTLIKQEIEKEEENLEVVLQQLSKHKTELknvadilqletNELQSLKLQHDQKVVELEKTQVDLLEGK 1739
Cdd:PRK04863   366 EQNEVVEEADEQQEENEARAEAAEEEVDELKSQLADYQQAL-----------DVQQTRAIQYQQAVQALERAKQLCGLPD 434

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1740 LELESL----------QQTAQQQRRELERQRQLLERDRRETERVRAETQALQSCIEcLNKEKEHLQEQCESWEKKSSHAK 1809
Cdd:PRK04863   435 LTADNAedwleefqakEQEATEELLSLEQKLSVAQAAHSQFEQAYQLVRKIAGEVS-RSEAWDVARELLRRLREQRHLAE 513

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1810 RVLAAteesnnteQSKLGQLEVSVRKLQQELELLSQ--DKLALHSDSAQEQQQLQDKREA-LNSLQKELEN-------TQ 1879
Cdd:PRK04863   514 QLQQL--------RMRLSELEQRLRQQQRAERLLAEfcKRLGKNLDDEDELEQLQEELEArLESLSESVSEarerrmaLR 585

                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1958764989 1880 DHLNLAKQDLMHTTKCQSALLSEQAQLQKDVSQWTARLESCQ------KETETKEQQLQELQDEIRESKLQLDQQ 1948
Cdd:PRK04863   586 QQLEQLQARIQRLAARAPAWLAAQDALARLREQSGEEFEDSQdvteymQQLLERERELTVERDELAARKQALDEE 660
HMMR_N pfam15905
Hyaluronan mediated motility receptor N-terminal; HMMR_N is the N-terminal region of ...
 609-767 3.90e-03

Hyaluronan mediated motility receptor N-terminal; HMMR_N is the N-terminal region of eukaryotic hyaluronan-mediated motility receptor proteins. The protein is functionally associated with BRCA1 and thus predicted to be a common, low-penetrance breast cancer candidate.


Pssm-ID: 464932 [Multi-domain]  Cd Length: 329  Bit Score: 41.72  E-value: 3.90e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  609 ALKKDLEGVISGLQEYLGTIKGQAAQAQNECRKLQDEKETLLQRLTEVKQEKDELEIVAMDAENMRKELAELENALQEQH 688
Cdd:pfam15905  177 AKQEGMEGKLQVTQKNLEHSKGKVAQLEEKLVSTEKEKIEEKSETEKLLEYITELSCVSEQVEKYKLDIAQLEELLKEKN 256

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1958764989  689 EVNASLQQaqgDLSAYETELETQLKLKDAETSQLKQELENLVRRTQLEQSVLQTELEKERQSLRDalgKAQSSEEKQQE 767
Cdd:pfam15905  257 DEIESLKQ---SLEEKEQELSKQIKDLNEKCKLLESEKEELLREYEEKEQTLNAELEELKEKLTL---EEQEHQKLQQK 329
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 1608-2138 4.31e-03

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 42.47  E-value: 4.31e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1608 RREELLLLQDSLTQAKADLQEALTLGETEVAEKCSHIREVKSLLEELSFQKGELNVHISERRTQLTLIKQEIEKEEENLE 1687
Cdd:pfam01576    2 RQEEEMQAKEEELQKVKERQQKAESELKELEKKHQQLCEEKNALQEQLQAETELCAEAEEMRARLAARKQELEEILHELE 81

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1688 VVL-------QQLSKHKTELK-NVADI-LQLETNELQSLKLQHDQKVVE--LEKTQVDLL-----------EGKLELESL 1745
Cdd:pfam01576   82 SRLeeeeersQQLQNEKKKMQqHIQDLeEQLDEEEAARQKLQLEKVTTEakIKKLEEDILlledqnsklskERKLLEERI 161

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1746 QQTAQQQRRELERQRQL-------------LERDRRETERVRAETQALQSCIEclnKEKEHLQEQCESWEKKSSHAKRVL 1812
Cdd:pfam01576  162 SEFTSNLAEEEEKAKSLsklknkheamisdLEERLKKEEKGRQELEKAKRKLE---GESTDLQEQIAELQAQIAELRAQL 238

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1813 AATEESNNTEQSKL-------GQLEVSVRKLQQELELLSQDKLALHSDSAQEQQQLQDKREALNSLQKELENTQDHLNlA 1885
Cdd:pfam01576  239 AKKEEELQAALARLeeetaqkNNALKKIRELEAQISELQEDLESERAARNKAEKQRRDLGEELEALKTELEDTLDTTA-A 317

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1886 KQDLMHTTKCQSALL---------SEQAQLQKDVSQWTARLESCQKETE--------------TKEQQLQELQDEIResk 1942
Cdd:pfam01576  318 QQELRSKREQEVTELkkaleeetrSHEAQLQEMRQKHTQALEELTEQLEqakrnkanlekakqALESENAELQAELR--- 394

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1943 lQLDQQEMVFQKLQKERESEEQKLVASIVSLEQQQGQLERELMDQKSKLEWLLTDVSAAEGRLRTLQKEercTESLEKML 2022
Cdd:pfam01576  395 -TLQQAKQDSEHKRKKLEGQLQELQARLSESERQRAELAEKLSKLQSELESVSSLLNEAEGKNIKLSKD---VSSLESQL 470

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 2023 SQAKQQLSEREQQLMEKSGDLLALQKEADGMRADFsllrNQFLTERKKAEKQVAGLKEALKIQRSQLEKNLLEQKQENSC 2102
Cdd:pfam01576  471 QDTQELLQEETRQKLNLSTRLRQLEDERNSLQEQL----EEEEEAKRNVERQLSTLQAQLSDMKKKLEEDAGTLEALEEG 546

                          570       580       590
                   ....*....|....*....|....*....|....*....
gi 1958764989 2103 MQKEMATIELVAQDNHERAR---RLMKELRQMQQEYLEL 2138
Cdd:pfam01576  547 KKRLQRELEALTQQLEEKAAaydKLEKTKNRLQQELDDL 585
ClpA COG0542
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein ...
 578-686 4.38e-03

ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440308 [Multi-domain]  Cd Length: 836  Bit Score: 42.38  E-value: 4.38e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  578 LDEILCRIATET----EEIKDLEQQLTDGQIAAnEALKKDLEgviSGLQEYLGTIKGQAAQAQNECRKLQDEKETLLQRL 653
Cdd:COG0542    395 IDEAAARVRMEIdskpEELDELERRLEQLEIEK-EALKKEQD---EASFERLAELRDELAELEEELEALKARWEAEKELI 470

                           90       100       110
                   ....*....|....*....|....*....|...
gi 1958764989  654 TEVKQEKDELEIVAMDAENMRKELAELENALQE 686
Cdd:COG0542    471 EEIQELKEELEQRYGKIPELEKELAELEEELAE 503
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1515-1982 4.56e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 42.06  E-value: 4.56e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1515 IKQEEILKEINKVVAAKDADFQCLNEKKEKLTEELQSLQRDIKAA--EVNEDHHLQVLKESESLLQAKRAELETLKSQVT 1592
Cdd:COG4717     70 LKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELreELEKLEKLLQLLPLYQELEALEAELAELPERLE 149

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1593 SQQQELAvldsQLGHRREELLLLQDSLTQAKADLQEALTLGETEVAEKCS-HIREVKSLLEELSFQKGELNVhiSERRTQ 1671
Cdd:COG4717    150 ELEERLE----ELRELEEELEELEAELAELQEELEELLEQLSLATEEELQdLAEELEELQQRLAELEEELEE--AQEELE 223

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1672 LTLIKQEIEKEEENLEVVLQQLSKHKTELKNVADILQLETNELQSLKLQHDQKVVELEKTQVdLLEGKLELESLQQTAQQ 1751
Cdd:COG4717    224 ELEEELEQLENELEAAALEERLKEARLLLLIAAALLALLGLGGSLLSLILTIAGVLFLVLGL-LALLFLLLAREKASLGK 302

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1752 QRRELERQRQLLERDRRETERVRAETQALQSC-IECLNKEKEHLQEQCESWEKKSSHAKRVlaateesnnteqsklgQLE 1830
Cdd:COG4717    303 EAEELQALPALEELEEEELEELLAALGLPPDLsPEELLELLDRIEELQELLREAEELEEEL----------------QLE 366

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1831 VSVRKLQQELELLSQDKLALHSDSAQEQQQLQDKREALNSLQKELENtqdHLNLAKQDLMHTTKcqSALLSEQAQLQKDV 1910
Cdd:COG4717    367 ELEQEIAALLAEAGVEDEEELRAALEQAEEYQELKEELEELEEQLEE---LLGELEELLEALDE--EELEEELEELEEEL 441

                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1958764989 1911 SQWTARLESCQKETETKEQQLQELQDEIRESKLQLDQQEMVFQKLQKERESEEQKLVASIVSLEQQQGQLER 1982
Cdd:COG4717    442 EELEEELEELREELAELEAELEQLEEDGELAELLQELEELKAELRELAEEWAALKLALELLEEAREEYREER 513
DUF3450 pfam11932
Protein of unknown function (DUF3450); This family of proteins are functionally ...
 1897-2051 4.60e-03

Protein of unknown function (DUF3450); This family of proteins are functionally uncharacterized. This protein is found in bacteria and eukaryotes. Proteins in this family are about 260 amino acids in length.


Pssm-ID: 432198 [Multi-domain]  Cd Length: 238  Bit Score: 41.06  E-value: 4.60e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1897 SALLSEQAQLQKDVSQWTARLESCQKETETKEQQLQELQDEIRESKLQLDQQEmvFQKLQKERESEEQKlvASIVSLEQQ 1976
Cdd:pfam11932    9 GALAATLDQALDLAEKAVAAAAQSQKKIDKWDDEKQELLAEYRALKAELESLE--VYNRQLERLVASQE--QEIASLERQ 84

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1977 QGQLERelmdQKSKLEWLLTDVSAaegRLRTL-------QKEERCT--ESLEKMLSQAKQQLSEREQQLMEksgdllALQ 2047
Cdd:pfam11932   85 IEEIER----TERELVPLMLKMLD---RLEQFvaldlpfLLEERQArlARLRELMDDADVSLAEKYRRILE------AYQ 151


                   ....
gi 1958764989 2048 KEAD 2051
Cdd:pfam11932  152 VEAE 155
PspC_subgroup_1 NF033838
pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, ...
 606-968 4.65e-03

pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A. The other form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site.


Pssm-ID: 468201 [Multi-domain]  Cd Length: 684  Bit Score: 41.92  E-value: 4.65e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  606 ANEALKKDLEGVISGLQEYLGTI-----KGQAAQAQNECRKLQDEKETLLQRLTEVKqEKDELEIVA-----MDA--ENM 673
Cdd:NF033838    52 GNESQKEHAKEVESHLEKILSEIqksldKRKHTQNVALNKKLSDIKTEYLYELNVLK-EKSEAELTSktkkeLDAafEQF 130

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  674 RKELAELENALQE-QHEVNASLQQAQG----DLSAYET------EL---ETQLKLKDAETSQLKQElenlVRRTQLEQSV 739
Cdd:NF033838   131 KKDTLEPGKKVAEaTKKVEEAEKKAKDqkeeDRRNYPTntyktlELeiaESDVEVKKAELELVKEE----AKEPRDEEKI 206

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  740 LQTELEKE-RQSLRDALGKAQSSEEKQQENSELRA--QLKQLQDDNSLLKKQLKDfQSHLNHVVDGlihpeeVAARVDEL 816
Cdd:NF033838   207 KQAKAKVEsKKAEATRLEKIKTDREKAEEEAKRRAdaKLKEAVEKNVATSEQDKP-KRRAKRGVLG------EPATPDKK 279

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  817 RKRLKLGA---GEMRIHSPSDVLGKSLADLQKQFSEILARSQWEKEE-----AQVRERKLHEEMALQQEKLANGQEEFKQ 888
Cdd:NF033838   280 ENDAKSSDssvGEETLPSPSLKPEKKVAEAEKKVEEAKKKAKDQKEEdrrnyPTNTYKTLELEIAESDVKVKEAELELVK 359

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  889 acERALEARIKFDKRQHNARIQQLENEIHYLqenlksmEKIQglTDlqLQEADEEKERILAqlqelEKKKRREDARSQEQ 968
Cdd:NF033838   360 --EEAKEPRNEEKIKQAKAKVESKKAEATRL-------EKIK--TD--RKKAEEEAKRKAA-----EEDKVKEKPAEQPQ 421
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 838-1070 4.75e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 41.67  E-value: 4.75e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  838 KSLADLQKQFSEI---LARSQWEKEEAQVRERKLHEEMALQQEKLANGQEEFKQACER--ALEARIKFDKRQHNARIQQL 912
Cdd:COG4942     20 DAAAEAEAELEQLqqeIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQElaALEAELAELEKEIAELRAEL 99

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  913 ENEIHYLQENLKSMEKIQGLTDLQL---QEADEEKERILAQLQELeKKKRREDARSQEQFLGLDTELKSLKKAVAASDKL 989
Cdd:COG4942    100 EAQKEELAELLRALYRLGRQPPLALllsPEDFLDAVRRLQYLKYL-APARREQAEELRADLAELAALRAELEAERAELEA 178

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  990 AAAELTIAKEQLKSLHgtvmrinQERAEELQEAERSSREAMQAAKDLSRAEAEIE-LLQHLLREREGQFRDEMENAHVGS 1068
Cdd:COG4942    179 LLAELEEERAALEALK-------AERQKLLARLEKELAELAAELAELQQEAEELEaLIARLEAEAAAAAERTPAAGFAAL 251


                   ..
gi 1958764989 1069 KG 1070
Cdd:COG4942    252 KG 253
PRK11637 PRK11637
AmiB activator; Provisional
 1837-2043 4.97e-03

AmiB activator; Provisional


Pssm-ID: 236942 [Multi-domain]  Cd Length: 428  Bit Score: 41.60  E-value: 4.97e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1837 QQELELLSQDkLALHSDSAQEQQ--------QLQDKREALNSLQKELENTQDHLNLAKQDLMHTTKCQSALLSEQAQLQK 1908
Cdd:PRK11637    46 RDQLKSIQQD-IAAKEKSVRQQQqqrasllaQLKKQEEAISQASRKLRETQNTLNQLNKQIDELNASIAKLEQQQAAQER 124

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1909 DVSQW------------------------------------TARLESCQKETETKE---QQLQELQDEIRESKLQLDQQE 1949
Cdd:PRK11637   125 LLAAQldaafrqgehtglqlilsgeesqrgerilayfgylnQARQETIAELKQTREelaAQKAELEEKQSQQKTLLYEQQ 204

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1950 MVFQKLQKERESEEQKLVASIVSLEQQQGQL------ERELMDQKSKLEwlltdvsaAEGRLRTlQKEERCTESLEKMLS 2023
Cdd:PRK11637   205 AQQQKLEQARNERKKTLTGLESSLQKDQQQLselranESRLRDSIARAE--------REAKARA-EREAREAARVRDKQK 275

                          250       260
                   ....*....|....*....|....*
gi 1958764989 2024 QAKQ-----QLSEREQQLMEKSGDL 2043
Cdd:PRK11637   276 QAKRkgstyKPTESERSLMSRTGGL 300
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 1431-1838 5.13e-03

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 42.25  E-value: 5.13e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1431 LKRRSELREADRLLAEAESELACTKEKTKSAVEKFTDAKRNLLQTESDAEALEKRAQETA--LNLV----KAEQQLRLLQ 1504
Cdd:COG3096    274 MRHANERRELSERALELRRELFGARRQLAEEQYRLVEMARELEELSARESDLEQDYQAASdhLNLVqtalRQQEKIERYQ 353

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1505 ADAEDLEQHKIKQEEILKEINKVVAAKDADFQCLNEKKEKLTEELQSLQRDIKAAE---VNEDHHLQVLKESESLLQAKR 1581
Cdd:COG3096    354 EDLEELTERLEEQEEVVEEAAEQLAEAEARLEAAEEEVDSLKSQLADYQQALDVQQtraIQYQQAVQALEKARALCGLPD 433

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1582 AELETLKSQVTSQQQELAVLDSQLGHRREELLLLQDSLTQAKADLQEALTL-GETEVAEKCSHIREvksLLEELSFQKge 1660
Cdd:COG3096    434 LTPENAEDYLAAFRAKEQQATEEVLELEQKLSVADAARRQFEKAYELVCKIaGEVERSQAWQTARE---LLRRYRSQQ-- 508

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1661 lnvHISERRTQLTLIkqeiekeeenlevvLQQLSKHKTELKNVADILQlETNELQSLKLQHDQKVVELEKTQVDLLEgkl 1740
Cdd:COG3096    509 ---ALAQRLQQLRAQ--------------LAELEQRLRQQQNAERLLE-EFCQRIGQQLDAAEELEELLAELEAQLE--- 567

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1741 ELESLQQTAQQQRRELERQRQLLERDRRETERVRAETQALQsciECLNKEKEHLQEQCESWEKKSSHAKRVL----AATE 1816
Cdd:COG3096    568 ELEEQAAEAVEQRSELRQQLEQLRARIKELAARAPAWLAAQ---DALERLREQSGEALADSQEVTAAMQQLLererEATV 644

                          410       420
                   ....*....|....*....|..
gi 1958764989 1817 ESNNTEQSKlGQLEVSVRKLQQ 1838
Cdd:COG3096    645 ERDELAARK-QALESQIERLSQ 665
COG4995 COG4995
Uncharacterized conserved protein, contains CHAT domain [Function unknown];
620-1051 6.03e-03

Uncharacterized conserved protein, contains CHAT domain [Function unknown];


Pssm-ID: 444019 [Multi-domain]  Cd Length: 711  Bit Score: 41.88  E-value: 6.03e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  620 GLQEYLGTIKGQAAQAQNECRKLQDEKETLLQRLTEVKQEKDELEIVAMDAENMRKELAELENALQEQHEVNASLQQAQG 699
Cdd:COG4995     14 LAALALALLALALLLLLAALAAAALLLLALLALLLALAAAAAAALAAAALALALLAAAALALLLLALALAALALALLAAA 93

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  700 DLSAYETELETQLKLKDAETSQLKQELENLVRRTQLEQSVLQTELEKERQSLRDALGKAQSSEEKQQENSELRAQLKQLQ 779
Cdd:COG4995     94 LALALAAAALAALALLAALLALAAAAALLALLAALALLALLAALAAALAAAAAAALAAALAAAAAAAAAAALLALALALA 173

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  780 DDN-SLLKKQLKDFQSHLNHVVDGLIHPEEVAARVDELRKRLKLGAGEMRIHSPSDVLGKSLADLQKQFSEILARSQWEK 858
Cdd:COG4995    174 AAAlALLALLLAALAAALAAAAAALALLLALLLLAALAAALAAALAALLLALLALAAALLALLLLALLALAAAAAALAAA 253

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  859 EEAQVRERKLHEEMALQQEKLANGQEEFKQACERALEARIKFDKRQHNARIQQLENEIHYLQENLKSMEKIQGLTDLQLQ 938
Cdd:COG4995    254 AAALLALAAALLLLAALAALAAAAAAAALAALALAAALALAAAALALALLLAAAAAAALAALALLLLAALLLLLAALALL 333

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  939 EADEEKERILAQLQELEKKKRREDARSQEQFLGLDTELKSLKKAVAASDKLAAAELTIAKEQLKSLHGTVMRINQERAEE 1018
Cdd:COG4995    334 ALLLLLAAAALLAAALAAALALAAALALALLAALLLLLAALLALLLEALLLLLLALLAALLLLAAALLALAAAQLLRLLL 413

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|....
gi 1958764989 1019 LQEAERSSREAMQAAKDLS-----------RAEAEIELLQHLLR 1051
Cdd:COG4995    414 AALALLLALAAYAAARLALlalieyiilpdRLYAFVQLYQLLIA 457
CusB_dom_1 pfam00529
Cation efflux system protein CusB domain 1; The cation efflux system protein CusB from E. coli ...
 601-761 6.25e-03

Cation efflux system protein CusB domain 1; The cation efflux system protein CusB from E. coli can be divided into four different domains, the first three domains of the protein are mostly beta-strands and the fourth forms an all alpha-helical domain. This entry represents the first beta-domain (domain 1) of CusB and it is formed by the N and C-terminal ends of the polypeptide (residues 89-102 and 324-385). CusB is part of the copper-transporting efflux system CusCFBA. This domain can also be found in other membrane-fusion proteins, such as HlyD, MdtN, MdtE and AaeA. HlyD is a component of the prototypical alpha-haemolysin (HlyA) bacterial type I secretion system, along with the other components HlyB and TolC. HlyD is anchored in the cytoplasmic membrane by a single transmembrane domain and has a large periplasmic domain within the carboxy-terminal 100 amino acids, HlyB and HlyD form a stable complex that binds the recombinant protein bearing a C-terminal HlyA signal sequence and ATP in the cytoplasm. HlyD, HlyB and TolC combine to form the three-component ABC transporter complex that forms a trans-membrane channel or pore through which HlyA can be transferred directly to the extracellular medium. Cutinase has been shown to be transported effectively through this pore.


Pssm-ID: 425733 [Multi-domain]  Cd Length: 322  Bit Score: 41.25  E-value: 6.25e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  601 DGQIAANEALKKDLEGVISGLQEYLGTIKGQAAQAQNECRKLQDEKETLLQRLTEVKQEKDELEivamDAENMRKELAEL 680
Cdd:pfam00529   64 EAQLAKAQAQVARLQAELDRLQALESELAISRQDYDGATAQLRAAQAAVKAAQAQLAQAQIDLA----RRRVLAPIGGIS 139

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  681 ENALQEQhevNASLQQAQGDLSAYETELETQLKLKDAETSQLKQELENLVRRTQLEQSVLQTELEKERQSLRDALGKAQS 760
Cdd:pfam00529  140 RESLVTA---GALVAQAQANLLATVAQLDQIYVQITQSAAENQAEVRSELSGAQLQIAEAEAELKLAKLDLERTEIRAPV 216


                   .
gi 1958764989  761 S 761
Cdd:pfam00529  217 D 217
COG5022 COG5022
Myosin heavy chain [General function prediction only];
435-1019 6.30e-03

Myosin heavy chain [General function prediction only];


Pssm-ID: 227355 [Multi-domain]  Cd Length: 1463  Bit Score: 41.99  E-value: 6.30e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  435 PDVQLEDTGKQIVAAQTRLSELHHEIEAAEQKVLRATQEFKQLEEAIRQKKISEAEKDLLLKQLSGRLRHLNKLRQEALD 514
Cdd:COG5022    866 KETIYLQSAQRVELAERQLQELKIDVKSISSLKLVNLELESEIIELKKSLSSDLIENLEFKTELIARLKKLLNNIDLEEG 945

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  515 LEAQLEKQrKEIAEKHEEINSAQLATDLLDSKDPKQSHMKAQKRGKEQQLDIMNKQYTQLESRLDeilcRIATETEEIKD 594
Cdd:COG5022    946 PSIEYVKL-PELNKLHEVESKLKETSEEYEDLLKKSTILVREGNKANSELKNFKKELAELSKQYG----ALQESTKQLKE 1020

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  595 LEQQLT--------DGQIAANEALKKDLEGVISGLqeylgTIKGQAAQAQNECRKLQDEKETLLQRLTEV--KQEKDELE 664
Cdd:COG5022   1021 LPVEVAelqsaskiISSESTELSILKPLQKLKGLL-----LLENNQLQARYKALKLRRENSLLDDKQLYQleSTENLLKT 1095

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  665 IVAMDAENMRKELAELENALQ----------EQHEVNASLQQAQGDLSAYETELETQLKLKDAETSQLkqeleNLVRRTQ 734
Cdd:COG5022   1096 INVKDLEVTNRNLVKPANVLQfivaqmiklnLLQEISKFLSQLVNTLEPVFQKLSVLQLELDGLFWEA-----NLEALPS 1170

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  735 LEQSVLQTELEKERQSLRDALGKAQSSEEKQQENsELRAQLKQLQDdNSLLKKQLKDFQSHLnhvvdglIHPEEVAARVD 814
Cdd:COG5022   1171 PPPFAALSEKRLYQSALYDEKSKLSSSEVNDLKN-ELIALFSKIFS-GWPRGDKLKKLISEG-------WVPTEYSTSLK 1241

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  815 ELRKRLKlgagemrihSPSDVLGKSLADLQKQFSEILARSQWEKEEAQVRERKLHEEMalQQEKLANGQEEFKQACERAL 894
Cdd:COG5022   1242 GFNNLNK---------KFDTPASMSNEKLLSLLNSIDNLLSSYKLEEEVLPATINSLL--QYINVGLFNALRTKASSLRW 1310

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  895 EARIKFDKRQHNARIQQLENEIHYLQENLKSMEKIQGLtdLQLQEADEEKERILAQLQELEKKKRREDARSQEQFLGLDT 974
Cdd:COG5022   1311 KSATEVNYNSEELDDWCREFEISDVDEELEELIQAVKV--LQLLKDDLNKLDELLDACYSLNPAEIQNLKSRYDPADKEN 1388

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|....*.
gi 1958764989  975 EL-KSLKKAVAAsdKLAAAELTIAKEQLKSLHGTVMRINQERAEEL 1019
Cdd:COG5022   1389 NLpKEILKKIEA--LLIKQELQLSLEGKDETEVHLSEIFSEEKSLI 1432
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 631-881 7.00e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 41.29  E-value: 7.00e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  631 QAAQAQNECRKLQDEKETLLQRLTEVKQEKDELEIvamDAENMRKELAELENALQEQHEVNASLQQAQGDLSAYETELET 710
Cdd:COG4942     21 AAAEAEAELEQLQQEIAELEKELAALKKEEKALLK---QLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRA 97

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  711 QLKlkdaetsQLKQELENLVRRTQLEQSVLQTELEKERQSLRDALGKAQSSEEKQQENSELRAQLKQLQDDNSLLKKQLK 790
Cdd:COG4942     98 ELE-------AQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELE 170

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  791 DFQSHLnhvvdglihpEEVAARVDELRKRLKLGAGEMRihspsdvlgKSLADLQKQFSEILARSQwEKEEAQVRERKLHE 870
Cdd:COG4942    171 AERAEL----------EALLAELEEERAALEALKAERQ---------KLLARLEKELAELAAELA-ELQQEAEELEALIA 230

                          250
                   ....*....|.
gi 1958764989  871 EMALQQEKLAN 881
Cdd:COG4942    231 RLEAEAAAAAE 241
COG1340 COG1340
Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown];
1856-2123 7.39e-03

Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown];


Pssm-ID: 440951 [Multi-domain]  Cd Length: 297  Bit Score: 40.66  E-value: 7.39e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1856 QEQQQLQDKREALNSLQKELENTQDHLNLAKQDLmhttkcqSALLSEQAQLQKDVSQWTARLESCQKETETKEQQLQELQ 1935
Cdd:COG1340     22 EEIEELKEKRDELNEELKELAEKRDELNAQVKEL-------REEAQELREKRDELNEKVKELKEERDELNEKLNELREEL 94

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1936 DEIRESKLQLDQQEMVFQKLQKERESEEQKLVASIVSLEQqqgqlERELMDQKSKLEWLLTDVSAAEGRLRTLQKEERCT 2015
Cdd:COG1340     95 DELRKELAELNKAGGSIDKLRKEIERLEWRQQTEVLSPEE-----EKELVEKIKELEKELEKAKKALEKNEKLKELRAEL 169

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 2016 ESLEKMLSQAKQQLSEREQQLMEKSGDLLALQKEADGMRADFSLLRNQFLTERKKAEKQVAGLKEAL-KIQRSQLEKNLL 2094
Cdd:COG1340    170 KELRKEAEEIHKKIKELAEEAQELHEEMIELYKEADELRKEADELHKEIVEAQEKADELHEEIIELQkELRELRKELKKL 249

                          250       260
                   ....*....|....*....|....*....
gi 1958764989 2095 EQKQENSCMQKEMATIELVAQDNHERARR 2123
Cdd:COG1340    250 RKKQRALKREKEKEELEEKAEEIFEKLKK 278
LRR_RI cd00116
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ...
 86-225 7.47e-03

Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).


Pssm-ID: 238064 [Multi-domain]  Cd Length: 319  Bit Score: 40.80  E-value: 7.47e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989   86 ALIKKLTKQDNLALVKSLNLSLSKDGGKKFryIENLEKCV-KLEVLNLSYNLI--AKIEKVDKLLR----LRELNLSYNK 158
Cdd:cd00116     99 GVLESLLRSSSLQELKLNNNGLGDRGLRLL--AKGLKDLPpALEKLVLGRNRLegASCEALAKALRanrdLKELNLANNG 176

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1958764989  159 ISK------IEGLENMCNLQKLNLAGNEIEHIPGWF----SKKLKSLRVLNLKGNKISSLqDVSKLKPLQDLTSLTL 225
Cdd:cd00116    177 IGDagiralAEGLKANCNLEVLDLNNNGLTDEGASAlaetLASLKSLEVLNLGDNNLTDA-GAAALASALLSPNISL 252
mukB PRK04863
chromosome partition protein MukB;
569-897 7.86e-03

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 41.48  E-value: 7.86e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  569 KQYTQLESRLDEILCRIATETEEIKDLEQQLTDGQ--IAANEAL--KKDLEGVISGLQEYLGTIKGQAAQAQNECRKLQD 644
Cdd:PRK04863   786 KRIEQLRAEREELAERYATLSFDVQKLQRLHQAFSrfIGSHLAVafEADPEAELRQLNRRRVELERALADHESQEQQQRS 865

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  645 EKETLLQRLTEVKQEKDELEIvaMDAENMRKELAELENALQEQHEVNASLQQAQGDLSAYETELETqLKLKDAETSQLKQ 724
Cdd:PRK04863   866 QLEQAKEGLSALNRLLPRLNL--LADETLADRVEEIREQLDEAEEAKRFVQQHGNALAQLEPIVSV-LQSDPEQFEQLKQ 942

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  725 ELENLvrRTQLEQSVLQTELEKERQSLRDALGKAQSSE---EKQQENSELRAQLKQLQDDNSLLKKQLKDFQSHL---NH 798
Cdd:PRK04863   943 DYQQA--QQTQRDAKQQAFALTEVVQRRAHFSYEDAAEmlaKNSDLNEKLRQRLEQAEQERTRAREQLRQAQAQLaqyNQ 1020

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  799 VVDGLIHPEEVAAR-VDELRKRLKlgagEMRIHSPSDVLGKSLADlQKQFSEILARSQWEKEEAQVRERKLHEEMALQQE 877
Cdd:PRK04863  1021 VLASLKSSYDAKRQmLQELKQELQ----DLGVPADSGAEERARAR-RDELHARLSANRSRRNQLEKQLTFCEAEMDNLTK 1095

                          330       340
                   ....*....|....*....|
gi 1958764989  878 KLANGQEEFKQACERALEAR 897
Cdd:PRK04863  1096 KLRKLERDYHEMREQVVNAK 1115
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 1573-1832 8.48e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 40.97  E-value: 8.48e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1573 SESLLQAKRAELETLKSQVTSQQQELAVLDSQLGHRREELLLLQDSLTQAKADLQEAltlgETEVAEKCSHIREVKSLLE 1652
Cdd:COG3883     14 ADPQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKL----QAEIAEAEAEIEERREELG 89

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1653 EL---SFQKGELNVHISerrtqlTLIKQEIEKEEENLEVVLQQLSKHKTELknvadilqleTNELQSLKLQHDQKVVELE 1729
Cdd:COG3883     90 ERaraLYRSGGSVSYLD------VLLGSESFSDFLDRLSALSKIADADADL----------LEELKADKAELEAKKAELE 153

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1730 KTQVDLLEGKLELESLQQTAQQQRRELERQRQLLERDRRETERVRAETQALQSCIECLNKEKEHLQEQCESWEKKSSHAK 1809
Cdd:COG3883    154 AKLAELEALKAELEAAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAAA 233

                          250       260
                   ....*....|....*....|...
gi 1958764989 1810 RVLAATEESNNTEQSKLGQLEVS 1832
Cdd:COG3883    234 AAAAAAAAAAASAAGAGAAGAAG 256
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 1823-1970 8.67e-03

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 40.29  E-value: 8.67e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1823 QSKLGQLEVSVRKLQQELELLSQDKLALHSDSAQEQQQLQDKREALNSLQKELENTQDHLNLAKqdlmhTTKCQSALLSE 1902
Cdd:COG1579     23 EHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLGNVR-----NNKEYEALQKE 97

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1958764989 1903 QAQLQKDVSQ-------WTARLESCQKETETKEQQLQELQDEIRESKLQLDQQEMVFQKLQKERESEEQKLVASI 1970
Cdd:COG1579     98 IESLKRRISDledeileLMERIEELEEELAELEAELAELEAELEEKKAELDEELAELEAELEELEAEREELAAKI 172
TMPIT pfam07851
TMPIT-like protein; A number of members of this family are annotated as being transmembrane ...
 1865-1949 9.10e-03

TMPIT-like protein; A number of members of this family are annotated as being transmembrane proteins induced by tumour necrosis factor alpha, but no literature was found to support this.


Pssm-ID: 462288  Cd Length: 324  Bit Score: 40.65  E-value: 9.10e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1865 REALNSLQKELENTQDHLNLAKQDLMHTTKCQSALLSEQAQLQKDVSQWTARLESCQKETETKEQQL-QELQDEIRESKL 1943
Cdd:pfam07851    1 LEEWEELEKEFQQLQETHKEYKQKLEELSSLQTRCKKSIKHQKKRLKELKSSLKRLQRSSIEEDQSLiKELQEEIKERKA 80


                   ....*.
gi 1958764989 1944 QLDQQE 1949
Cdd:pfam07851   81 QLFEME 86
46 PHA02562
endonuclease subunit; Provisional
 612-818 9.30e-03

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 41.15  E-value: 9.30e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  612 KDLEGVISGLQEYLGT----IKGQAAQAQNECRKLQDEKETLLQRLTEVKQEKDELEIvamDAENMRKELAELENAL--- 684
Cdd:PHA02562   184 QTLDMKIDHIQQQIKTynknIEEQRKKNGENIARKQNKYDELVEEAKTIKAEIEELTD---ELLNLVMDIEDPSAALnkl 260

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  685 -QEQHEVNASLQQAQGDLSAYETELETQlklkdAETSQLKQElENLVRRTQLEQSVLQTELEKerqsLRDALGKAQSSEE 763
Cdd:PHA02562   261 nTAAAKIKSKIEQFQKVIKMYEKGGVCP-----TCTQQISEG-PDRITKIKDKLKELQHSLEK----LDTAIDELEEIMD 330

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  764 KQQENS----ELRAQLKQLQDDNSLLKKQLKDFQSHL-NHVVDGLIHPEEVAARVDELRK 818
Cdd:PHA02562   331 EFNEQSkkllELKNKISTNKQSLITLVDKAKKVKAAIeELQAEFVDNAEELAKLQDELDK 390
MAD pfam05557
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint ...
 1769-2055 9.33e-03

Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint (Mitotic arrest deficient or MAD) proteins. The mitotic spindle checkpoint monitors proper attachment of the bipolar spindle to the kinetochores of aligned sister chromatids and causes a cell cycle arrest in prometaphase when failures occur. Multiple components of the mitotic spindle checkpoint have been identified in yeast and higher eukaryotes. In S.cerevisiae, the existence of a Mad1-dependent complex containing Mad2, Mad3, Bub3 and Cdc20 has been demonstrated.


Pssm-ID: 461677 [Multi-domain]  Cd Length: 660  Bit Score: 41.26  E-value: 9.33e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1769 ETERVRAETQALQSCIECLNKEKEHLQEQCESwEKKSSHAKRVLAATEESNNTEQSKLGQLEvsvrklqqELELLSQDKL 1848
Cdd:pfam05557    1 RAELIESKARLSQLQNEKKQMELEHKRARIEL-EKKASALKRQLDRESDRNQELQKRIRLLE--------KREAEAEEAL 71

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1849 alhSDSAQEQQQLQDKREALNSLQKElentqdhlnlakqdlmhttkcQSALLSEQAQLQKDVSQWTARLescQKETETKE 1928
Cdd:pfam05557   72 ---REQAELNRLKKKYLEALNKKLNE---------------------KESQLADAREVISCLKNELSEL---RRQIQRAE 124

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989 1929 QQLQELQDEIRESKLQLDQQEMVFQKLQKERESEEQKLVASIVSlEQQQGQLERELMDQKSKLEwLLTDVSAAEGRLRTL 2008
Cdd:pfam05557  125 LELQSTNSELEELQERLDLLKAKASEAEQLRQNLEKQQSSLAEA-EQRIKELEFEIQSQEQDSE-IVKNSKSELARIPEL 202

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*..
gi 1958764989 2009 QKEercteslekmlsqaKQQLSEREQQLMEKSGDLLALQKEADGMRA 2055
Cdd:pfam05557  203 EKE--------------LERLREHNKHLNENIENKLLLKEEVEDLKR 235
hsdR PRK11448
type I restriction enzyme EcoKI subunit R; Provisional
 636-754 9.61e-03

type I restriction enzyme EcoKI subunit R; Provisional


Pssm-ID: 236912 [Multi-domain]  Cd Length: 1123  Bit Score: 41.09  E-value: 9.61e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958764989  636 QNECRKLQDEKETLLQRLTEVKQEKDELEIvamDAENMRKELAELEnALQEQHEvnaslqqaqGDLSAYETELEtQLKLK 715
Cdd:PRK11448   141 ENLLHALQQEVLTLKQQLELQAREKAQSQA---LAEAQQQELVALE-GLAAELE---------EKQQELEAQLE-QLQEK 206

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|...
gi 1958764989  716 DAETSQlkQELENLVRRT-QLEQSVLQTELEKER---QSLRDA 754
Cdd:PRK11448   207 AAETSQ--ERKQKRKEITdQAAKRLELSEEETRIlidQQLRKA 247
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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