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Conserved domains on  [gi|1958769205|ref|XP_038963410|]
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small ribosomal subunit protein mS35 isoform X5 [Rattus norvegicus]

Protein Classification

mS35 family ribosomal protein( domain architecture ID 1904147)

mS35 family ribosomal protein such as fungal 37S ribosomal protein S24, a component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain

Gene Ontology:  GO:0003723|GO:0003735|GO:0032543
PubMed:  27023846

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
MRP-S28 super family cl44596
Mitochondrial ribosomal subunit protein; This is a conserved region of approx. 125 residues of ...
 162-208 3.87e-05

Mitochondrial ribosomal subunit protein; This is a conserved region of approx. 125 residues of one of the proteins that makes up the small subunit of the mitochondrial ribosome. In Saccharomyces cerevisiae the protein is MRP-S24 whereas in humans it is MRP-S28. The human mitochondrial ribosome has 29 distinct proteins in the small subunit and these have homologs in, for example, Drosophila melanogaster, Caenorhabditis elegans, and in the genomes of several fungi.


The actual alignment was detected with superfamily member pfam10213:

Pssm-ID: 463002  Cd Length: 126  Bit Score: 41.98  E-value: 3.87e-05
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*..
gi 1958769205 162 NPRARAVTLRVKLSSLNLDNHAKKKLIKLVGERYCKTTDVLTIKTDR 208
Cdd:pfam10213  23 HPASRKVVLEVKPADLGLEEKQLHKLKLLAGPRYNPETDIIKMSSEK 69
 
Name Accession Description Interval E-value
MRP-S28 pfam10213
Mitochondrial ribosomal subunit protein; This is a conserved region of approx. 125 residues of ...
 162-208 3.87e-05

Mitochondrial ribosomal subunit protein; This is a conserved region of approx. 125 residues of one of the proteins that makes up the small subunit of the mitochondrial ribosome. In Saccharomyces cerevisiae the protein is MRP-S24 whereas in humans it is MRP-S28. The human mitochondrial ribosome has 29 distinct proteins in the small subunit and these have homologs in, for example, Drosophila melanogaster, Caenorhabditis elegans, and in the genomes of several fungi.


Pssm-ID: 463002  Cd Length: 126  Bit Score: 41.98  E-value: 3.87e-05
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*..
gi 1958769205 162 NPRARAVTLRVKLSSLNLDNHAKKKLIKLVGERYCKTTDVLTIKTDR 208
Cdd:pfam10213  23 HPASRKVVLEVKPADLGLEEKQLHKLKLLAGPRYNPETDIIKMSSEK 69
 
Name Accession Description Interval E-value
MRP-S28 pfam10213
Mitochondrial ribosomal subunit protein; This is a conserved region of approx. 125 residues of ...
 162-208 3.87e-05

Mitochondrial ribosomal subunit protein; This is a conserved region of approx. 125 residues of one of the proteins that makes up the small subunit of the mitochondrial ribosome. In Saccharomyces cerevisiae the protein is MRP-S24 whereas in humans it is MRP-S28. The human mitochondrial ribosome has 29 distinct proteins in the small subunit and these have homologs in, for example, Drosophila melanogaster, Caenorhabditis elegans, and in the genomes of several fungi.


Pssm-ID: 463002  Cd Length: 126  Bit Score: 41.98  E-value: 3.87e-05
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*..
gi 1958769205 162 NPRARAVTLRVKLSSLNLDNHAKKKLIKLVGERYCKTTDVLTIKTDR 208
Cdd:pfam10213  23 HPASRKVVLEVKPADLGLEEKQLHKLKLLAGPRYNPETDIIKMSSEK 69
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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